Index by author
May 01, 2016; Volume 44,Issue 5
B
Bairlein, Michaela
- You have accessCurrent Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White PaperEugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. MooreDrug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
Ballent, Mariana
- You have accessThe ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy CowsHanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra HalwachsDrug Metabolism and Disposition May 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
Barfield, Matthew
- You have accessCurrent Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White PaperEugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. MooreDrug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
Baumann, Sven
- You have accessThe ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy CowsHanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra HalwachsDrug Metabolism and Disposition May 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
Bi, Huichang
- You have accessSchisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in MiceXi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang BiDrug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
Boerner, Julie
- You have accessEpidermal Growth Factor Receptor Kinase Inhibitors Synergize with TCDD to Induce CYP1A1/1A2 in Human Breast Epithelial MCF10A CellsAby Joiakim, Patricia A. Mathieu, Catherine Shelp, Julie Boerner and John J. ReinersDrug Metabolism and Disposition May 2016, 44 (5) 665-671; DOI: https://doi.org/10.1124/dmd.115.066274
Bostick, Chris D.
- You have accessImmobilized Cytochrome P450 for Monitoring of P450-P450 Interactions and MetabolismChris D. Bostick, Katherine M. Hickey, Lance A. Wollenberg, Darcy R. Flora, Timothy S. Tracy and Peter M. GannettDrug Metabolism and Disposition May 2016, 44 (5) 741-749; DOI: https://doi.org/10.1124/dmd.115.067637
Brocker, Chad N.
- You have accessGlycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated ApoptosisTingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping HaoDrug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
Brodney, Michael A.
- You have accessBiosynthesis of Fluorinated Analogs of Drugs Using Human Cytochrome P450 Enzymes Followed by Deoxyfluorination and Quantitative Nuclear Magnetic Resonance Spectroscopy to Improve Metabolic StabilityR. Scott Obach, Gregory S. Walker and Michael A. BrodneyDrug Metabolism and Disposition May 2016, 44 (5) 634-646; DOI: https://doi.org/10.1124/dmd.116.069310
C
Callahan, Shellie M.
- You have accessIntegrin Receptors Play a Key Role in the Regulation of Hepatic CYP3AKristina Jonsson-Schmunk, Piynauch Wonganan, Jin Huk Choi, Shellie M. Callahan and Maria A. CroyleDrug Metabolism and Disposition May 2016, 44 (5) 758-770; DOI: https://doi.org/10.1124/dmd.115.068874
Callegari, Ernesto
- You have accessMechanistic Modeling to Predict Midazolam Metabolite Exposure from In Vitro DataHoa Q. Nguyen, Emi Kimoto, Ernesto Callegari and R. Scott ObachDrug Metabolism and Disposition May 2016, 44 (5) 781-791; DOI: https://doi.org/10.1124/dmd.115.068601
Chai, Yingying
- You have accessGlycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated ApoptosisTingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping HaoDrug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
Che, Yuan
- You have accessGlycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated ApoptosisTingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping HaoDrug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
Chemuturi, Nagendra V.
- You have accessCurrent Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White PaperEugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. MooreDrug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
Chen, Yixin
- You have accessSchisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in MiceXi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang BiDrug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
Cheng, Xuefang
- You have accessGlycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated ApoptosisTingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping HaoDrug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
Choi, Jin Huk
- You have accessIntegrin Receptors Play a Key Role in the Regulation of Hepatic CYP3AKristina Jonsson-Schmunk, Piynauch Wonganan, Jin Huk Choi, Shellie M. Callahan and Maria A. CroyleDrug Metabolism and Disposition May 2016, 44 (5) 758-770; DOI: https://doi.org/10.1124/dmd.115.068874
Cremers, Thomas I.F.H.
- You have accessDevelopment of a Rat Plasma and Brain Extracellular Fluid Pharmacokinetic Model for Bupropion and Hydroxybupropion Based on Microdialysis Sampling, and Application to Predict Human Brain ConcentrationsThomas I.F.H. Cremers, Gunnar Flik, Joost H.A. Folgering, Hans Rollema and Robert E. StratfordDrug Metabolism and Disposition May 2016, 44 (5) 624-633; DOI: https://doi.org/10.1124/dmd.115.068932
Croyle, Maria A.
- You have accessIntegrin Receptors Play a Key Role in the Regulation of Hepatic CYP3AKristina Jonsson-Schmunk, Piynauch Wonganan, Jin Huk Choi, Shellie M. Callahan and Maria A. CroyleDrug Metabolism and Disposition May 2016, 44 (5) 758-770; DOI: https://doi.org/10.1124/dmd.115.068874
D
Datta-Mannan, Amita
- You have accessCurrent Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White PaperEugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. MooreDrug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
de Graaf, Inge A. M.
- You have accessThe Consequence of Drug–Drug Interactions Influencing the Interplay between P-Glycoprotein and Cytochrome P450 3a: An Ex Vivo Study with Rat Precision-Cut Intestinal SlicesMing Li, Inge A. M. de Graaf, Sanna Siissalo, Marina H. de Jager, Annie van Dam and Geny M. M. GroothuisDrug Metabolism and Disposition May 2016, 44 (5) 683-691; DOI: https://doi.org/10.1124/dmd.115.068684
de Jager, Marina H.
- You have accessThe Consequence of Drug–Drug Interactions Influencing the Interplay between P-Glycoprotein and Cytochrome P450 3a: An Ex Vivo Study with Rat Precision-Cut Intestinal SlicesMing Li, Inge A. M. de Graaf, Sanna Siissalo, Marina H. de Jager, Annie van Dam and Geny M. M. GroothuisDrug Metabolism and Disposition May 2016, 44 (5) 683-691; DOI: https://doi.org/10.1124/dmd.115.068684
Deslandes, Antoine
- You have accessCurrent Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White PaperEugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. MooreDrug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
Di, Li
- You have accessThe Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced MyopathyHeather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. KalgutkarDrug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447
E
Eggimann, Fabian K.
- You have accessIdentification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and HumansSu-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. MangoldDrug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
Einolf, Heidi J.
- You have accessIdentification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and HumansSu-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. MangoldDrug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
Eng, Heather
- You have accessThe Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced MyopathyHeather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. KalgutkarDrug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447
Escandon, Enrique
- You have accessCurrent Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White PaperEugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. MooreDrug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
F
Fan, Xiaomei
- You have accessSchisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in MiceXi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang BiDrug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
Farooq, Muhammad
- You have accessRETRACTION: CYP2D6 Is Inducible by Endogenous and Exogenous CorticosteroidsMuhammad Farooq, Edward J. Kelly and Jashvant D. UnadkatDrug Metabolism and Disposition May 2016, 44 (5) 750-757; DOI: https://doi.org/10.1124/dmd.115.069229
Favara, Sarah
- You have accessIdentification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and HumansSu-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. MangoldDrug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
Feng, Bo
- You have accessThe Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced MyopathyHeather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. KalgutkarDrug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447
Flik, Gunnar
- You have accessDevelopment of a Rat Plasma and Brain Extracellular Fluid Pharmacokinetic Model for Bupropion and Hydroxybupropion Based on Microdialysis Sampling, and Application to Predict Human Brain ConcentrationsThomas I.F.H. Cremers, Gunnar Flik, Joost H.A. Folgering, Hans Rollema and Robert E. StratfordDrug Metabolism and Disposition May 2016, 44 (5) 624-633; DOI: https://doi.org/10.1124/dmd.115.068932
Flora, Darcy R.
- You have accessImmobilized Cytochrome P450 for Monitoring of P450-P450 Interactions and MetabolismChris D. Bostick, Katherine M. Hickey, Lance A. Wollenberg, Darcy R. Flora, Timothy S. Tracy and Peter M. GannettDrug Metabolism and Disposition May 2016, 44 (5) 741-749; DOI: https://doi.org/10.1124/dmd.115.067637
Folgering, Joost H.A.
- You have accessDevelopment of a Rat Plasma and Brain Extracellular Fluid Pharmacokinetic Model for Bupropion and Hydroxybupropion Based on Microdialysis Sampling, and Application to Predict Human Brain ConcentrationsThomas I.F.H. Cremers, Gunnar Flik, Joost H.A. Folgering, Hans Rollema and Robert E. StratfordDrug Metabolism and Disposition May 2016, 44 (5) 624-633; DOI: https://doi.org/10.1124/dmd.115.068932
Forseth, Ry R.
- You have accessIdentification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and HumansSu-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. MangoldDrug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
Fredenhagen, Andreas
- You have accessKAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male SubjectsSu-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. SteinDrug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
G
Gannett, Peter M.
- You have accessImmobilized Cytochrome P450 for Monitoring of P450-P450 Interactions and MetabolismChris D. Bostick, Katherine M. Hickey, Lance A. Wollenberg, Darcy R. Flora, Timothy S. Tracy and Peter M. GannettDrug Metabolism and Disposition May 2016, 44 (5) 741-749; DOI: https://doi.org/10.1124/dmd.115.067637
Ghoneim, Ragia H.
- You have accessEndotoxin-Mediated Downregulation of Hepatic Drug Transporters in HIV-1 Transgenic RatsRagia H. Ghoneim and Micheline Piquette-MillerDrug Metabolism and Disposition May 2016, 44 (5) 709-719; DOI: https://doi.org/10.1124/dmd.115.067827
Gonzalez, Frank J.
- You have accessGlycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated ApoptosisTingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping HaoDrug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
Groothuis, Geny M. M.
- You have accessThe Consequence of Drug–Drug Interactions Influencing the Interplay between P-Glycoprotein and Cytochrome P450 3a: An Ex Vivo Study with Rat Precision-Cut Intestinal SlicesMing Li, Inge A. M. de Graaf, Sanna Siissalo, Marina H. de Jager, Annie van Dam and Geny M. M. GroothuisDrug Metabolism and Disposition May 2016, 44 (5) 683-691; DOI: https://doi.org/10.1124/dmd.115.068684
Gu, Helen
- You have accessIdentification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and HumansSu-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. MangoldDrug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
H
Halwachs, Sandra
- You have accessThe ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy CowsHanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra HalwachsDrug Metabolism and Disposition May 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
Hammock, Bruce D.
- You have accessCatalytic Activities of Tumor-Specific Human Cytochrome P450 CYP2W1 Toward Endogenous SubstratesYan Zhao, Debin Wan, Jun Yang, Bruce D. Hammock and Paul R. Ortiz de MontellanoDrug Metabolism and Disposition May 2016, 44 (5) 771-780; DOI: https://doi.org/10.1124/dmd.116.069633
Hao, Haiping
- You have accessGlycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated ApoptosisTingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping HaoDrug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
Hayes, Martin A.
- You have accessDatabase Extraction of Metabolite Information of Drug Candidates: Analysis of 27 AstraZeneca Compounds with Human Absorption, Distribution, Metabolism, and Excretion DataJessica Iegre, Martin A. Hayes, Richard A. Thompson, Lars Weidolf and Emre M. IsinDrug Metabolism and Disposition May 2016, 44 (5) 732-740; DOI: https://doi.org/10.1124/dmd.115.067850
He, Handan
- You have accessIdentification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and HumansSu-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. MangoldDrug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
Hickey, Katherine M.
- You have accessImmobilized Cytochrome P450 for Monitoring of P450-P450 Interactions and MetabolismChris D. Bostick, Katherine M. Hickey, Lance A. Wollenberg, Darcy R. Flora, Timothy S. Tracy and Peter M. GannettDrug Metabolism and Disposition May 2016, 44 (5) 741-749; DOI: https://doi.org/10.1124/dmd.115.067637
Honscha, Walther
- You have accessThe ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy CowsHanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra HalwachsDrug Metabolism and Disposition May 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
Huang, Min
- You have accessSchisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in MiceXi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang BiDrug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
Huskey, Su-Er W.
- You have accessKAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male SubjectsSu-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. SteinDrug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
- You have accessIdentification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and HumansSu-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. MangoldDrug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
I
Iegre, Jessica
- You have accessDatabase Extraction of Metabolite Information of Drug Candidates: Analysis of 27 AstraZeneca Compounds with Human Absorption, Distribution, Metabolism, and Excretion DataJessica Iegre, Martin A. Hayes, Richard A. Thompson, Lars Weidolf and Emre M. IsinDrug Metabolism and Disposition May 2016, 44 (5) 732-740; DOI: https://doi.org/10.1124/dmd.115.067850
Imperiale, Fernanda
- You have accessThe ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy CowsHanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra HalwachsDrug Metabolism and Disposition May 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
Isin, Emre M.
- You have accessDatabase Extraction of Metabolite Information of Drug Candidates: Analysis of 27 AstraZeneca Compounds with Human Absorption, Distribution, Metabolism, and Excretion DataJessica Iegre, Martin A. Hayes, Richard A. Thompson, Lars Weidolf and Emre M. IsinDrug Metabolism and Disposition May 2016, 44 (5) 732-740; DOI: https://doi.org/10.1124/dmd.115.067850
Iyer, Ramaswamy A.
- You have accessCurrent Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White PaperEugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. MooreDrug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
J
Jain, Jay P.
- You have accessKAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male SubjectsSu-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. SteinDrug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
Jian, Zhigang
- You have accessKAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male SubjectsSu-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. SteinDrug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
Joiakim, Aby
- You have accessEpidermal Growth Factor Receptor Kinase Inhibitors Synergize with TCDD to Induce CYP1A1/1A2 in Human Breast Epithelial MCF10A CellsAby Joiakim, Patricia A. Mathieu, Catherine Shelp, Julie Boerner and John J. ReinersDrug Metabolism and Disposition May 2016, 44 (5) 665-671; DOI: https://doi.org/10.1124/dmd.115.066274
Jonsson-Schmunk, Kristina
- You have accessIntegrin Receptors Play a Key Role in the Regulation of Hepatic CYP3AKristina Jonsson-Schmunk, Piynauch Wonganan, Jin Huk Choi, Shellie M. Callahan and Maria A. CroyleDrug Metabolism and Disposition May 2016, 44 (5) 758-770; DOI: https://doi.org/10.1124/dmd.115.068874
K
Kalgutkar, Amit S.
- You have accessThe Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced MyopathyHeather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. KalgutkarDrug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447
Kamath, Amrita V.
- You have accessCurrent Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White PaperEugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. MooreDrug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
Kelly, Edward J.
- You have accessRETRACTION: CYP2D6 Is Inducible by Endogenous and Exogenous CorticosteroidsMuhammad Farooq, Edward J. Kelly and Jashvant D. UnadkatDrug Metabolism and Disposition May 2016, 44 (5) 750-757; DOI: https://doi.org/10.1124/dmd.115.069229
Kimoto, Emi
- You have accessMechanistic Modeling to Predict Midazolam Metabolite Exposure from In Vitro DataHoa Q. Nguyen, Emi Kimoto, Ernesto Callegari and R. Scott ObachDrug Metabolism and Disposition May 2016, 44 (5) 781-791; DOI: https://doi.org/10.1124/dmd.115.068601
Kittelmann, Matthias
- You have accessIdentification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and HumansSu-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. MangoldDrug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
Krausz, Kristopher W.
- You have accessGlycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated ApoptosisTingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping HaoDrug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
Kraynov, Eugenia
- You have accessCurrent Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White PaperEugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. MooreDrug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
Kühnöl, Jürgen
- You have accessKAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male SubjectsSu-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. SteinDrug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
L
Lanusse, Carlos
- You have accessThe ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy CowsHanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra HalwachsDrug Metabolism and Disposition May 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
Lazzaro, Sarah
- You have accessThe Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced MyopathyHeather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. KalgutkarDrug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447
Li, Dongshun
- You have accessSchisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in MiceXi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang BiDrug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
Li, Feiyan
- You have accessGlycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated ApoptosisTingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping HaoDrug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
Li, Hongmei
- You have accessIdentification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and HumansSu-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. MangoldDrug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
Li, Ming
- You have accessThe Consequence of Drug–Drug Interactions Influencing the Interplay between P-Glycoprotein and Cytochrome P450 3a: An Ex Vivo Study with Rat Precision-Cut Intestinal SlicesMing Li, Inge A. M. de Graaf, Sanna Siissalo, Marina H. de Jager, Annie van Dam and Geny M. M. GroothuisDrug Metabolism and Disposition May 2016, 44 (5) 683-691; DOI: https://doi.org/10.1124/dmd.115.068684
Li, Xi
- You have accessSchisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in MiceXi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang BiDrug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
Lifschitz, Adrian L.
- You have accessThe ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy CowsHanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra HalwachsDrug Metabolism and Disposition May 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
Lin, Jian
- You have accessThe Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced MyopathyHeather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. KalgutkarDrug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447
Lin, Melissa M.
- You have accessIdentification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and HumansSu-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. MangoldDrug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
Luneau, Alexandre
- You have accessKAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male SubjectsSu-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. SteinDrug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
- You have accessIdentification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and HumansSu-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. MangoldDrug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
M
Mahnke, Hanna
- You have accessThe ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy CowsHanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra HalwachsDrug Metabolism and Disposition May 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
Mangold, James B.
- You have accessKAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male SubjectsSu-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. SteinDrug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
- You have accessIdentification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and HumansSu-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. MangoldDrug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
Mathieu, Patricia A.
- You have accessEpidermal Growth Factor Receptor Kinase Inhibitors Synergize with TCDD to Induce CYP1A1/1A2 in Human Breast Epithelial MCF10A CellsAby Joiakim, Patricia A. Mathieu, Catherine Shelp, Julie Boerner and John J. ReinersDrug Metabolism and Disposition May 2016, 44 (5) 665-671; DOI: https://doi.org/10.1124/dmd.115.066274
Miao, Zhuang
- You have accessKAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male SubjectsSu-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. SteinDrug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
Moore, David J.
- You have accessCurrent Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White PaperEugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. MooreDrug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
N
Nguyen, Hoa Q.
- You have accessMechanistic Modeling to Predict Midazolam Metabolite Exposure from In Vitro DataHoa Q. Nguyen, Emi Kimoto, Ernesto Callegari and R. Scott ObachDrug Metabolism and Disposition May 2016, 44 (5) 781-791; DOI: https://doi.org/10.1124/dmd.115.068601
O
Obach, R. Scott
- You have accessBiosynthesis of Fluorinated Analogs of Drugs Using Human Cytochrome P450 Enzymes Followed by Deoxyfluorination and Quantitative Nuclear Magnetic Resonance Spectroscopy to Improve Metabolic StabilityR. Scott Obach, Gregory S. Walker and Michael A. BrodneyDrug Metabolism and Disposition May 2016, 44 (5) 634-646; DOI: https://doi.org/10.1124/dmd.116.069310
- You have accessMechanistic Modeling to Predict Midazolam Metabolite Exposure from In Vitro DataHoa Q. Nguyen, Emi Kimoto, Ernesto Callegari and R. Scott ObachDrug Metabolism and Disposition May 2016, 44 (5) 781-791; DOI: https://doi.org/10.1124/dmd.115.068601
Ortiz de Montellano, Paul R.
- You have accessCatalytic Activities of Tumor-Specific Human Cytochrome P450 CYP2W1 Toward Endogenous SubstratesYan Zhao, Debin Wan, Jun Yang, Bruce D. Hammock and Paul R. Ortiz de MontellanoDrug Metabolism and Disposition May 2016, 44 (5) 771-780; DOI: https://doi.org/10.1124/dmd.116.069633
P
Piquette-Miller, Micheline
- You have accessEndotoxin-Mediated Downregulation of Hepatic Drug Transporters in HIV-1 Transgenic RatsRagia H. Ghoneim and Micheline Piquette-MillerDrug Metabolism and Disposition May 2016, 44 (5) 709-719; DOI: https://doi.org/10.1124/dmd.115.067827
R
Reiners, John J.
- You have accessEpidermal Growth Factor Receptor Kinase Inhibitors Synergize with TCDD to Induce CYP1A1/1A2 in Human Breast Epithelial MCF10A CellsAby Joiakim, Patricia A. Mathieu, Catherine Shelp, Julie Boerner and John J. ReinersDrug Metabolism and Disposition May 2016, 44 (5) 665-671; DOI: https://doi.org/10.1124/dmd.115.066274
Rock, Dan A.
- You have accessCurrent Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White PaperEugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. MooreDrug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
Rollema, Hans
- You have accessDevelopment of a Rat Plasma and Brain Extracellular Fluid Pharmacokinetic Model for Bupropion and Hydroxybupropion Based on Microdialysis Sampling, and Application to Predict Human Brain ConcentrationsThomas I.F.H. Cremers, Gunnar Flik, Joost H.A. Folgering, Hans Rollema and Robert E. StratfordDrug Metabolism and Disposition May 2016, 44 (5) 624-633; DOI: https://doi.org/10.1124/dmd.115.068932
Rotter, Charles J.
- You have accessThe Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced MyopathyHeather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. KalgutkarDrug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447
S
Scialis, Renato J.
- You have accessThe Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced MyopathyHeather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. KalgutkarDrug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447
Shelp, Catherine
- You have accessEpidermal Growth Factor Receptor Kinase Inhibitors Synergize with TCDD to Induce CYP1A1/1A2 in Human Breast Epithelial MCF10A CellsAby Joiakim, Patricia A. Mathieu, Catherine Shelp, Julie Boerner and John J. ReinersDrug Metabolism and Disposition May 2016, 44 (5) 665-671; DOI: https://doi.org/10.1124/dmd.115.066274
Siissalo, Sanna
- You have accessThe Consequence of Drug–Drug Interactions Influencing the Interplay between P-Glycoprotein and Cytochrome P450 3a: An Ex Vivo Study with Rat Precision-Cut Intestinal SlicesMing Li, Inge A. M. de Graaf, Sanna Siissalo, Marina H. de Jager, Annie van Dam and Geny M. M. GroothuisDrug Metabolism and Disposition May 2016, 44 (5) 683-691; DOI: https://doi.org/10.1124/dmd.115.068684
Simon, Oliver
- You have accessIdentification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and HumansSu-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. MangoldDrug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
Sriraman, Priya
- You have accessCurrent Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White PaperEugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. MooreDrug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
Stein, Daniel S.
- You have accessKAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male SubjectsSu-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. SteinDrug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
Stratford, Robert E.
- You have accessDevelopment of a Rat Plasma and Brain Extracellular Fluid Pharmacokinetic Model for Bupropion and Hydroxybupropion Based on Microdialysis Sampling, and Application to Predict Human Brain ConcentrationsThomas I.F.H. Cremers, Gunnar Flik, Joost H.A. Folgering, Hans Rollema and Robert E. StratfordDrug Metabolism and Disposition May 2016, 44 (5) 624-633; DOI: https://doi.org/10.1124/dmd.115.068932
Sunkara, Gangadhar
- You have accessKAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male SubjectsSu-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. SteinDrug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
T
Tarcsa, Edit
- You have accessCurrent Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White PaperEugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. MooreDrug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
Thompson, Richard A.
- You have accessDatabase Extraction of Metabolite Information of Drug Candidates: Analysis of 27 AstraZeneca Compounds with Human Absorption, Distribution, Metabolism, and Excretion DataJessica Iegre, Martin A. Hayes, Richard A. Thompson, Lars Weidolf and Emre M. IsinDrug Metabolism and Disposition May 2016, 44 (5) 732-740; DOI: https://doi.org/10.1124/dmd.115.067850
Tracy, Timothy S.
- You have accessImmobilized Cytochrome P450 for Monitoring of P450-P450 Interactions and MetabolismChris D. Bostick, Katherine M. Hickey, Lance A. Wollenberg, Darcy R. Flora, Timothy S. Tracy and Peter M. GannettDrug Metabolism and Disposition May 2016, 44 (5) 741-749; DOI: https://doi.org/10.1124/dmd.115.067637
U
Unadkat, Jashvant D.
- You have accessRETRACTION: CYP2D6 Is Inducible by Endogenous and Exogenous CorticosteroidsMuhammad Farooq, Edward J. Kelly and Jashvant D. UnadkatDrug Metabolism and Disposition May 2016, 44 (5) 750-757; DOI: https://doi.org/10.1124/dmd.115.069229
V
van Dam, Annie
- You have accessThe Consequence of Drug–Drug Interactions Influencing the Interplay between P-Glycoprotein and Cytochrome P450 3a: An Ex Vivo Study with Rat Precision-Cut Intestinal SlicesMing Li, Inge A. M. de Graaf, Sanna Siissalo, Marina H. de Jager, Annie van Dam and Geny M. M. GroothuisDrug Metabolism and Disposition May 2016, 44 (5) 683-691; DOI: https://doi.org/10.1124/dmd.115.068684
Vargas, Alexandra
- You have accessIdentification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and HumansSu-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. MangoldDrug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
Varma, Manthena V.
- You have accessThe Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced MyopathyHeather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. KalgutkarDrug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447
von Bergen, Martin
- You have accessThe ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy CowsHanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra HalwachsDrug Metabolism and Disposition May 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
W
Walker, Gregory S.
- You have accessBiosynthesis of Fluorinated Analogs of Drugs Using Human Cytochrome P450 Enzymes Followed by Deoxyfluorination and Quantitative Nuclear Magnetic Resonance Spectroscopy to Improve Metabolic StabilityR. Scott Obach, Gregory S. Walker and Michael A. BrodneyDrug Metabolism and Disposition May 2016, 44 (5) 634-646; DOI: https://doi.org/10.1124/dmd.116.069310
Walles, Markus
- You have accessCurrent Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White PaperEugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. MooreDrug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
Wan, Debin
- You have accessCatalytic Activities of Tumor-Specific Human Cytochrome P450 CYP2W1 Toward Endogenous SubstratesYan Zhao, Debin Wan, Jun Yang, Bruce D. Hammock and Paul R. Ortiz de MontellanoDrug Metabolism and Disposition May 2016, 44 (5) 771-780; DOI: https://doi.org/10.1124/dmd.116.069633
Wang, Guangji
- You have accessGlycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated ApoptosisTingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping HaoDrug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
Wang, Hong
- You have accessGlycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated ApoptosisTingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping HaoDrug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
Wang, Lai
- You have accessIdentification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and HumansSu-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. MangoldDrug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
Wang, Weirong
- You have accessCurrent Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White PaperEugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. MooreDrug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
Wang, Yongtao
- You have accessSchisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in MiceXi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang BiDrug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
Weidolf, Lars
- You have accessDatabase Extraction of Metabolite Information of Drug Candidates: Analysis of 27 AstraZeneca Compounds with Human Absorption, Distribution, Metabolism, and Excretion DataJessica Iegre, Martin A. Hayes, Richard A. Thompson, Lars Weidolf and Emre M. IsinDrug Metabolism and Disposition May 2016, 44 (5) 732-740; DOI: https://doi.org/10.1124/dmd.115.067850
West, Michael
- You have accessThe Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced MyopathyHeather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. KalgutkarDrug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447
Wollenberg, Lance A.
- You have accessImmobilized Cytochrome P450 for Monitoring of P450-P450 Interactions and MetabolismChris D. Bostick, Katherine M. Hickey, Lance A. Wollenberg, Darcy R. Flora, Timothy S. Tracy and Peter M. GannettDrug Metabolism and Disposition May 2016, 44 (5) 741-749; DOI: https://doi.org/10.1124/dmd.115.067637
Wonganan, Piynauch
- You have accessIntegrin Receptors Play a Key Role in the Regulation of Hepatic CYP3AKristina Jonsson-Schmunk, Piynauch Wonganan, Jin Huk Choi, Shellie M. Callahan and Maria A. CroyleDrug Metabolism and Disposition May 2016, 44 (5) 758-770; DOI: https://doi.org/10.1124/dmd.115.068874
Wu, Yuzheng
- You have accessGlycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated ApoptosisTingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping HaoDrug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
X
Xiao, Guangqing
- You have accessCurrent Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White PaperEugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. MooreDrug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
Xie, Cen
- You have accessGlycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated ApoptosisTingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping HaoDrug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
Y
Yagai, Tomoki
- You have accessGlycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated ApoptosisTingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping HaoDrug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
Yan, Tingting
- You have accessGlycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated ApoptosisTingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping HaoDrug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
Yang, Fan
- You have accessKAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male SubjectsSu-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. SteinDrug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
Yang, Johnny J.
- You have accessCurrent Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White PaperEugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. MooreDrug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
Yang, Jun
- You have accessCatalytic Activities of Tumor-Specific Human Cytochrome P450 CYP2W1 Toward Endogenous SubstratesYan Zhao, Debin Wan, Jun Yang, Bruce D. Hammock and Paul R. Ortiz de MontellanoDrug Metabolism and Disposition May 2016, 44 (5) 771-780; DOI: https://doi.org/10.1124/dmd.116.069633
Yang, Ziping
- You have accessKAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male SubjectsSu-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. SteinDrug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
Z
Zeng, Hang
- You have accessSchisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in MiceXi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang BiDrug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
Zeng, Xuezhen
- You have accessSchisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in MiceXi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang BiDrug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
Zhang, Jin
- You have accessIdentification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and HumansSu-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. MangoldDrug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
Zhang, Jun
- You have accessGlycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated ApoptosisTingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping HaoDrug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
Zhao, Min
- You have accessGlycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated ApoptosisTingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping HaoDrug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
Zhao, Yan
- You have accessCatalytic Activities of Tumor-Specific Human Cytochrome P450 CYP2W1 Toward Endogenous SubstratesYan Zhao, Debin Wan, Jun Yang, Bruce D. Hammock and Paul R. Ortiz de MontellanoDrug Metabolism and Disposition May 2016, 44 (5) 771-780; DOI: https://doi.org/10.1124/dmd.116.069633
Zhou, Yawen
- You have accessSchisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in MiceXi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang BiDrug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
Zhu, Chun-qi
- You have accessKAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male SubjectsSu-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. SteinDrug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
- You have accessIdentification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and HumansSu-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. MangoldDrug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
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