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Drug Metabolism & Disposition

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    • Current Issue
    • Fast Forward
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Index by author

May 01, 2016; Volume 44,Issue 5
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

B

  1. Bairlein, Michaela

    1. You have access
      Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
      Eugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. Moore
      Drug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
  2. Ballent, Mariana

    1. You have access
      The ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy Cows
      Hanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra Halwachs
      Drug Metabolism and Disposition May 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
  3. Barfield, Matthew

    1. You have access
      Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
      Eugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. Moore
      Drug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
  4. Baumann, Sven

    1. You have access
      The ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy Cows
      Hanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra Halwachs
      Drug Metabolism and Disposition May 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
  5. Bi, Huichang

    1. You have access
      Schisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in Mice
      Xi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang Bi
      Drug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
  6. Boerner, Julie

    1. You have access
      Epidermal Growth Factor Receptor Kinase Inhibitors Synergize with TCDD to Induce CYP1A1/1A2 in Human Breast Epithelial MCF10A Cells
      Aby Joiakim, Patricia A. Mathieu, Catherine Shelp, Julie Boerner and John J. Reiners
      Drug Metabolism and Disposition May 2016, 44 (5) 665-671; DOI: https://doi.org/10.1124/dmd.115.066274
  7. Bostick, Chris D.

    1. You have access
      Immobilized Cytochrome P450 for Monitoring of P450-P450 Interactions and Metabolism
      Chris D. Bostick, Katherine M. Hickey, Lance A. Wollenberg, Darcy R. Flora, Timothy S. Tracy and Peter M. Gannett
      Drug Metabolism and Disposition May 2016, 44 (5) 741-749; DOI: https://doi.org/10.1124/dmd.115.067637
  8. Brocker, Chad N.

    1. You have access
      Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated Apoptosis
      Tingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping Hao
      Drug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
  9. Brodney, Michael A.

    1. You have access
      Biosynthesis of Fluorinated Analogs of Drugs Using Human Cytochrome P450 Enzymes Followed by Deoxyfluorination and Quantitative Nuclear Magnetic Resonance Spectroscopy to Improve Metabolic Stability
      R. Scott Obach, Gregory S. Walker and Michael A. Brodney
      Drug Metabolism and Disposition May 2016, 44 (5) 634-646; DOI: https://doi.org/10.1124/dmd.116.069310

C

  1. Callahan, Shellie M.

    1. You have access
      Integrin Receptors Play a Key Role in the Regulation of Hepatic CYP3A
      Kristina Jonsson-Schmunk, Piynauch Wonganan, Jin Huk Choi, Shellie M. Callahan and Maria A. Croyle
      Drug Metabolism and Disposition May 2016, 44 (5) 758-770; DOI: https://doi.org/10.1124/dmd.115.068874
  2. Callegari, Ernesto

    1. You have access
      Mechanistic Modeling to Predict Midazolam Metabolite Exposure from In Vitro Data
      Hoa Q. Nguyen, Emi Kimoto, Ernesto Callegari and R. Scott Obach
      Drug Metabolism and Disposition May 2016, 44 (5) 781-791; DOI: https://doi.org/10.1124/dmd.115.068601
  3. Chai, Yingying

    1. You have access
      Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated Apoptosis
      Tingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping Hao
      Drug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
  4. Che, Yuan

    1. You have access
      Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated Apoptosis
      Tingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping Hao
      Drug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
  5. Chemuturi, Nagendra V.

    1. You have access
      Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
      Eugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. Moore
      Drug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
  6. Chen, Yixin

    1. You have access
      Schisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in Mice
      Xi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang Bi
      Drug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
  7. Cheng, Xuefang

    1. You have access
      Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated Apoptosis
      Tingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping Hao
      Drug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
  8. Choi, Jin Huk

    1. You have access
      Integrin Receptors Play a Key Role in the Regulation of Hepatic CYP3A
      Kristina Jonsson-Schmunk, Piynauch Wonganan, Jin Huk Choi, Shellie M. Callahan and Maria A. Croyle
      Drug Metabolism and Disposition May 2016, 44 (5) 758-770; DOI: https://doi.org/10.1124/dmd.115.068874
  9. Cremers, Thomas I.F.H.

    1. You have access
      Development of a Rat Plasma and Brain Extracellular Fluid Pharmacokinetic Model for Bupropion and Hydroxybupropion Based on Microdialysis Sampling, and Application to Predict Human Brain Concentrations
      Thomas I.F.H. Cremers, Gunnar Flik, Joost H.A. Folgering, Hans Rollema and Robert E. Stratford
      Drug Metabolism and Disposition May 2016, 44 (5) 624-633; DOI: https://doi.org/10.1124/dmd.115.068932
  10. Croyle, Maria A.

    1. You have access
      Integrin Receptors Play a Key Role in the Regulation of Hepatic CYP3A
      Kristina Jonsson-Schmunk, Piynauch Wonganan, Jin Huk Choi, Shellie M. Callahan and Maria A. Croyle
      Drug Metabolism and Disposition May 2016, 44 (5) 758-770; DOI: https://doi.org/10.1124/dmd.115.068874

D

  1. Datta-Mannan, Amita

    1. You have access
      Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
      Eugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. Moore
      Drug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
  2. de Graaf, Inge A. M.

    1. You have access
      The Consequence of Drug–Drug Interactions Influencing the Interplay between P-Glycoprotein and Cytochrome P450 3a: An Ex Vivo Study with Rat Precision-Cut Intestinal Slices
      Ming Li, Inge A. M. de Graaf, Sanna Siissalo, Marina H. de Jager, Annie van Dam and Geny M. M. Groothuis
      Drug Metabolism and Disposition May 2016, 44 (5) 683-691; DOI: https://doi.org/10.1124/dmd.115.068684
  3. de Jager, Marina H.

    1. You have access
      The Consequence of Drug–Drug Interactions Influencing the Interplay between P-Glycoprotein and Cytochrome P450 3a: An Ex Vivo Study with Rat Precision-Cut Intestinal Slices
      Ming Li, Inge A. M. de Graaf, Sanna Siissalo, Marina H. de Jager, Annie van Dam and Geny M. M. Groothuis
      Drug Metabolism and Disposition May 2016, 44 (5) 683-691; DOI: https://doi.org/10.1124/dmd.115.068684
  4. Deslandes, Antoine

    1. You have access
      Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
      Eugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. Moore
      Drug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
  5. Di, Li

    1. You have access
      The Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced Myopathy
      Heather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447

E

  1. Eggimann, Fabian K.

    1. You have access
      Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans
      Su-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. Mangold
      Drug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
  2. Einolf, Heidi J.

    1. You have access
      Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans
      Su-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. Mangold
      Drug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
  3. Eng, Heather

    1. You have access
      The Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced Myopathy
      Heather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447
  4. Escandon, Enrique

    1. You have access
      Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
      Eugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. Moore
      Drug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049

F

  1. Fan, Xiaomei

    1. You have access
      Schisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in Mice
      Xi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang Bi
      Drug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
  2. Farooq, Muhammad

    1. You have access
      RETRACTION: CYP2D6 Is Inducible by Endogenous and Exogenous Corticosteroids
      Muhammad Farooq, Edward J. Kelly and Jashvant D. Unadkat
      Drug Metabolism and Disposition May 2016, 44 (5) 750-757; DOI: https://doi.org/10.1124/dmd.115.069229
  3. Favara, Sarah

    1. You have access
      Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans
      Su-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. Mangold
      Drug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
  4. Feng, Bo

    1. You have access
      The Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced Myopathy
      Heather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447
  5. Flik, Gunnar

    1. You have access
      Development of a Rat Plasma and Brain Extracellular Fluid Pharmacokinetic Model for Bupropion and Hydroxybupropion Based on Microdialysis Sampling, and Application to Predict Human Brain Concentrations
      Thomas I.F.H. Cremers, Gunnar Flik, Joost H.A. Folgering, Hans Rollema and Robert E. Stratford
      Drug Metabolism and Disposition May 2016, 44 (5) 624-633; DOI: https://doi.org/10.1124/dmd.115.068932
  6. Flora, Darcy R.

    1. You have access
      Immobilized Cytochrome P450 for Monitoring of P450-P450 Interactions and Metabolism
      Chris D. Bostick, Katherine M. Hickey, Lance A. Wollenberg, Darcy R. Flora, Timothy S. Tracy and Peter M. Gannett
      Drug Metabolism and Disposition May 2016, 44 (5) 741-749; DOI: https://doi.org/10.1124/dmd.115.067637
  7. Folgering, Joost H.A.

    1. You have access
      Development of a Rat Plasma and Brain Extracellular Fluid Pharmacokinetic Model for Bupropion and Hydroxybupropion Based on Microdialysis Sampling, and Application to Predict Human Brain Concentrations
      Thomas I.F.H. Cremers, Gunnar Flik, Joost H.A. Folgering, Hans Rollema and Robert E. Stratford
      Drug Metabolism and Disposition May 2016, 44 (5) 624-633; DOI: https://doi.org/10.1124/dmd.115.068932
  8. Forseth, Ry R.

    1. You have access
      Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans
      Su-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. Mangold
      Drug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
  9. Fredenhagen, Andreas

    1. You have access
      KAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male Subjects
      Su-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. Stein
      Drug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187

G

  1. Gannett, Peter M.

    1. You have access
      Immobilized Cytochrome P450 for Monitoring of P450-P450 Interactions and Metabolism
      Chris D. Bostick, Katherine M. Hickey, Lance A. Wollenberg, Darcy R. Flora, Timothy S. Tracy and Peter M. Gannett
      Drug Metabolism and Disposition May 2016, 44 (5) 741-749; DOI: https://doi.org/10.1124/dmd.115.067637
  2. Ghoneim, Ragia H.

    1. You have access
      Endotoxin-Mediated Downregulation of Hepatic Drug Transporters in HIV-1 Transgenic Rats
      Ragia H. Ghoneim and Micheline Piquette-Miller
      Drug Metabolism and Disposition May 2016, 44 (5) 709-719; DOI: https://doi.org/10.1124/dmd.115.067827
  3. Gonzalez, Frank J.

    1. You have access
      Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated Apoptosis
      Tingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping Hao
      Drug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
  4. Groothuis, Geny M. M.

    1. You have access
      The Consequence of Drug–Drug Interactions Influencing the Interplay between P-Glycoprotein and Cytochrome P450 3a: An Ex Vivo Study with Rat Precision-Cut Intestinal Slices
      Ming Li, Inge A. M. de Graaf, Sanna Siissalo, Marina H. de Jager, Annie van Dam and Geny M. M. Groothuis
      Drug Metabolism and Disposition May 2016, 44 (5) 683-691; DOI: https://doi.org/10.1124/dmd.115.068684
  5. Gu, Helen

    1. You have access
      Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans
      Su-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. Mangold
      Drug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112

H

  1. Halwachs, Sandra

    1. You have access
      The ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy Cows
      Hanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra Halwachs
      Drug Metabolism and Disposition May 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
  2. Hammock, Bruce D.

    1. You have access
      Catalytic Activities of Tumor-Specific Human Cytochrome P450 CYP2W1 Toward Endogenous Substrates
      Yan Zhao, Debin Wan, Jun Yang, Bruce D. Hammock and Paul R. Ortiz de Montellano
      Drug Metabolism and Disposition May 2016, 44 (5) 771-780; DOI: https://doi.org/10.1124/dmd.116.069633
  3. Hao, Haiping

    1. You have access
      Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated Apoptosis
      Tingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping Hao
      Drug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
  4. Hayes, Martin A.

    1. Database Extraction of Metabolite Information of Drug Candidates: Analysis of 27 AstraZeneca Compounds with Human Absorption, Distribution, Metabolism, and Excretion Data
      You have access
      Database Extraction of Metabolite Information of Drug Candidates: Analysis of 27 AstraZeneca Compounds with Human Absorption, Distribution, Metabolism, and Excretion Data
      Jessica Iegre, Martin A. Hayes, Richard A. Thompson, Lars Weidolf and Emre M. Isin
      Drug Metabolism and Disposition May 2016, 44 (5) 732-740; DOI: https://doi.org/10.1124/dmd.115.067850
  5. He, Handan

    1. You have access
      Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans
      Su-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. Mangold
      Drug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
  6. Hickey, Katherine M.

    1. You have access
      Immobilized Cytochrome P450 for Monitoring of P450-P450 Interactions and Metabolism
      Chris D. Bostick, Katherine M. Hickey, Lance A. Wollenberg, Darcy R. Flora, Timothy S. Tracy and Peter M. Gannett
      Drug Metabolism and Disposition May 2016, 44 (5) 741-749; DOI: https://doi.org/10.1124/dmd.115.067637
  7. Honscha, Walther

    1. You have access
      The ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy Cows
      Hanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra Halwachs
      Drug Metabolism and Disposition May 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
  8. Huang, Min

    1. You have access
      Schisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in Mice
      Xi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang Bi
      Drug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
  9. Huskey, Su-Er W.

    1. You have access
      KAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male Subjects
      Su-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. Stein
      Drug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
    2. You have access
      Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans
      Su-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. Mangold
      Drug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112

I

  1. Iegre, Jessica

    1. Database Extraction of Metabolite Information of Drug Candidates: Analysis of 27 AstraZeneca Compounds with Human Absorption, Distribution, Metabolism, and Excretion Data
      You have access
      Database Extraction of Metabolite Information of Drug Candidates: Analysis of 27 AstraZeneca Compounds with Human Absorption, Distribution, Metabolism, and Excretion Data
      Jessica Iegre, Martin A. Hayes, Richard A. Thompson, Lars Weidolf and Emre M. Isin
      Drug Metabolism and Disposition May 2016, 44 (5) 732-740; DOI: https://doi.org/10.1124/dmd.115.067850
  2. Imperiale, Fernanda

    1. You have access
      The ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy Cows
      Hanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra Halwachs
      Drug Metabolism and Disposition May 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
  3. Isin, Emre M.

    1. Database Extraction of Metabolite Information of Drug Candidates: Analysis of 27 AstraZeneca Compounds with Human Absorption, Distribution, Metabolism, and Excretion Data
      You have access
      Database Extraction of Metabolite Information of Drug Candidates: Analysis of 27 AstraZeneca Compounds with Human Absorption, Distribution, Metabolism, and Excretion Data
      Jessica Iegre, Martin A. Hayes, Richard A. Thompson, Lars Weidolf and Emre M. Isin
      Drug Metabolism and Disposition May 2016, 44 (5) 732-740; DOI: https://doi.org/10.1124/dmd.115.067850
  4. Iyer, Ramaswamy A.

    1. You have access
      Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
      Eugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. Moore
      Drug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049

J

  1. Jain, Jay P.

    1. You have access
      KAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male Subjects
      Su-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. Stein
      Drug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
  2. Jian, Zhigang

    1. You have access
      KAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male Subjects
      Su-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. Stein
      Drug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
  3. Joiakim, Aby

    1. You have access
      Epidermal Growth Factor Receptor Kinase Inhibitors Synergize with TCDD to Induce CYP1A1/1A2 in Human Breast Epithelial MCF10A Cells
      Aby Joiakim, Patricia A. Mathieu, Catherine Shelp, Julie Boerner and John J. Reiners
      Drug Metabolism and Disposition May 2016, 44 (5) 665-671; DOI: https://doi.org/10.1124/dmd.115.066274
  4. Jonsson-Schmunk, Kristina

    1. You have access
      Integrin Receptors Play a Key Role in the Regulation of Hepatic CYP3A
      Kristina Jonsson-Schmunk, Piynauch Wonganan, Jin Huk Choi, Shellie M. Callahan and Maria A. Croyle
      Drug Metabolism and Disposition May 2016, 44 (5) 758-770; DOI: https://doi.org/10.1124/dmd.115.068874

K

  1. Kalgutkar, Amit S.

    1. You have access
      The Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced Myopathy
      Heather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447
  2. Kamath, Amrita V.

    1. You have access
      Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
      Eugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. Moore
      Drug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
  3. Kelly, Edward J.

    1. You have access
      RETRACTION: CYP2D6 Is Inducible by Endogenous and Exogenous Corticosteroids
      Muhammad Farooq, Edward J. Kelly and Jashvant D. Unadkat
      Drug Metabolism and Disposition May 2016, 44 (5) 750-757; DOI: https://doi.org/10.1124/dmd.115.069229
  4. Kimoto, Emi

    1. You have access
      Mechanistic Modeling to Predict Midazolam Metabolite Exposure from In Vitro Data
      Hoa Q. Nguyen, Emi Kimoto, Ernesto Callegari and R. Scott Obach
      Drug Metabolism and Disposition May 2016, 44 (5) 781-791; DOI: https://doi.org/10.1124/dmd.115.068601
  5. Kittelmann, Matthias

    1. You have access
      Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans
      Su-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. Mangold
      Drug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
  6. Krausz, Kristopher W.

    1. You have access
      Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated Apoptosis
      Tingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping Hao
      Drug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
  7. Kraynov, Eugenia

    1. You have access
      Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
      Eugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. Moore
      Drug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
  8. Kühnöl, Jürgen

    1. You have access
      KAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male Subjects
      Su-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. Stein
      Drug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187

L

  1. Lanusse, Carlos

    1. You have access
      The ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy Cows
      Hanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra Halwachs
      Drug Metabolism and Disposition May 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
  2. Lazzaro, Sarah

    1. You have access
      The Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced Myopathy
      Heather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447
  3. Li, Dongshun

    1. You have access
      Schisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in Mice
      Xi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang Bi
      Drug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
  4. Li, Feiyan

    1. You have access
      Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated Apoptosis
      Tingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping Hao
      Drug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
  5. Li, Hongmei

    1. You have access
      Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans
      Su-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. Mangold
      Drug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
  6. Li, Ming

    1. You have access
      The Consequence of Drug–Drug Interactions Influencing the Interplay between P-Glycoprotein and Cytochrome P450 3a: An Ex Vivo Study with Rat Precision-Cut Intestinal Slices
      Ming Li, Inge A. M. de Graaf, Sanna Siissalo, Marina H. de Jager, Annie van Dam and Geny M. M. Groothuis
      Drug Metabolism and Disposition May 2016, 44 (5) 683-691; DOI: https://doi.org/10.1124/dmd.115.068684
  7. Li, Xi

    1. You have access
      Schisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in Mice
      Xi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang Bi
      Drug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
  8. Lifschitz, Adrian L.

    1. You have access
      The ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy Cows
      Hanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra Halwachs
      Drug Metabolism and Disposition May 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
  9. Lin, Jian

    1. You have access
      The Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced Myopathy
      Heather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447
  10. Lin, Melissa M.

    1. You have access
      Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans
      Su-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. Mangold
      Drug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
  11. Luneau, Alexandre

    1. You have access
      KAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male Subjects
      Su-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. Stein
      Drug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
    2. You have access
      Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans
      Su-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. Mangold
      Drug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112

M

  1. Mahnke, Hanna

    1. You have access
      The ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy Cows
      Hanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra Halwachs
      Drug Metabolism and Disposition May 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940
  2. Mangold, James B.

    1. You have access
      KAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male Subjects
      Su-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. Stein
      Drug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
    2. You have access
      Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans
      Su-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. Mangold
      Drug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
  3. Mathieu, Patricia A.

    1. You have access
      Epidermal Growth Factor Receptor Kinase Inhibitors Synergize with TCDD to Induce CYP1A1/1A2 in Human Breast Epithelial MCF10A Cells
      Aby Joiakim, Patricia A. Mathieu, Catherine Shelp, Julie Boerner and John J. Reiners
      Drug Metabolism and Disposition May 2016, 44 (5) 665-671; DOI: https://doi.org/10.1124/dmd.115.066274
  4. Miao, Zhuang

    1. You have access
      KAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male Subjects
      Su-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. Stein
      Drug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
  5. Moore, David J.

    1. You have access
      Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
      Eugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. Moore
      Drug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049

N

  1. Nguyen, Hoa Q.

    1. You have access
      Mechanistic Modeling to Predict Midazolam Metabolite Exposure from In Vitro Data
      Hoa Q. Nguyen, Emi Kimoto, Ernesto Callegari and R. Scott Obach
      Drug Metabolism and Disposition May 2016, 44 (5) 781-791; DOI: https://doi.org/10.1124/dmd.115.068601

O

  1. Obach, R. Scott

    1. You have access
      Biosynthesis of Fluorinated Analogs of Drugs Using Human Cytochrome P450 Enzymes Followed by Deoxyfluorination and Quantitative Nuclear Magnetic Resonance Spectroscopy to Improve Metabolic Stability
      R. Scott Obach, Gregory S. Walker and Michael A. Brodney
      Drug Metabolism and Disposition May 2016, 44 (5) 634-646; DOI: https://doi.org/10.1124/dmd.116.069310
    2. You have access
      Mechanistic Modeling to Predict Midazolam Metabolite Exposure from In Vitro Data
      Hoa Q. Nguyen, Emi Kimoto, Ernesto Callegari and R. Scott Obach
      Drug Metabolism and Disposition May 2016, 44 (5) 781-791; DOI: https://doi.org/10.1124/dmd.115.068601
  2. Ortiz de Montellano, Paul R.

    1. You have access
      Catalytic Activities of Tumor-Specific Human Cytochrome P450 CYP2W1 Toward Endogenous Substrates
      Yan Zhao, Debin Wan, Jun Yang, Bruce D. Hammock and Paul R. Ortiz de Montellano
      Drug Metabolism and Disposition May 2016, 44 (5) 771-780; DOI: https://doi.org/10.1124/dmd.116.069633

P

  1. Piquette-Miller, Micheline

    1. You have access
      Endotoxin-Mediated Downregulation of Hepatic Drug Transporters in HIV-1 Transgenic Rats
      Ragia H. Ghoneim and Micheline Piquette-Miller
      Drug Metabolism and Disposition May 2016, 44 (5) 709-719; DOI: https://doi.org/10.1124/dmd.115.067827

R

  1. Reiners, John J.

    1. You have access
      Epidermal Growth Factor Receptor Kinase Inhibitors Synergize with TCDD to Induce CYP1A1/1A2 in Human Breast Epithelial MCF10A Cells
      Aby Joiakim, Patricia A. Mathieu, Catherine Shelp, Julie Boerner and John J. Reiners
      Drug Metabolism and Disposition May 2016, 44 (5) 665-671; DOI: https://doi.org/10.1124/dmd.115.066274
  2. Rock, Dan A.

    1. You have access
      Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
      Eugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. Moore
      Drug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
  3. Rollema, Hans

    1. You have access
      Development of a Rat Plasma and Brain Extracellular Fluid Pharmacokinetic Model for Bupropion and Hydroxybupropion Based on Microdialysis Sampling, and Application to Predict Human Brain Concentrations
      Thomas I.F.H. Cremers, Gunnar Flik, Joost H.A. Folgering, Hans Rollema and Robert E. Stratford
      Drug Metabolism and Disposition May 2016, 44 (5) 624-633; DOI: https://doi.org/10.1124/dmd.115.068932
  4. Rotter, Charles J.

    1. You have access
      The Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced Myopathy
      Heather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447

S

  1. Scialis, Renato J.

    1. You have access
      The Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced Myopathy
      Heather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447
  2. Shelp, Catherine

    1. You have access
      Epidermal Growth Factor Receptor Kinase Inhibitors Synergize with TCDD to Induce CYP1A1/1A2 in Human Breast Epithelial MCF10A Cells
      Aby Joiakim, Patricia A. Mathieu, Catherine Shelp, Julie Boerner and John J. Reiners
      Drug Metabolism and Disposition May 2016, 44 (5) 665-671; DOI: https://doi.org/10.1124/dmd.115.066274
  3. Siissalo, Sanna

    1. You have access
      The Consequence of Drug–Drug Interactions Influencing the Interplay between P-Glycoprotein and Cytochrome P450 3a: An Ex Vivo Study with Rat Precision-Cut Intestinal Slices
      Ming Li, Inge A. M. de Graaf, Sanna Siissalo, Marina H. de Jager, Annie van Dam and Geny M. M. Groothuis
      Drug Metabolism and Disposition May 2016, 44 (5) 683-691; DOI: https://doi.org/10.1124/dmd.115.068684
  4. Simon, Oliver

    1. You have access
      Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans
      Su-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. Mangold
      Drug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
  5. Sriraman, Priya

    1. You have access
      Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
      Eugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. Moore
      Drug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
  6. Stein, Daniel S.

    1. You have access
      KAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male Subjects
      Su-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. Stein
      Drug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
  7. Stratford, Robert E.

    1. You have access
      Development of a Rat Plasma and Brain Extracellular Fluid Pharmacokinetic Model for Bupropion and Hydroxybupropion Based on Microdialysis Sampling, and Application to Predict Human Brain Concentrations
      Thomas I.F.H. Cremers, Gunnar Flik, Joost H.A. Folgering, Hans Rollema and Robert E. Stratford
      Drug Metabolism and Disposition May 2016, 44 (5) 624-633; DOI: https://doi.org/10.1124/dmd.115.068932
  8. Sunkara, Gangadhar

    1. You have access
      KAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male Subjects
      Su-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. Stein
      Drug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187

T

  1. Tarcsa, Edit

    1. You have access
      Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
      Eugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. Moore
      Drug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
  2. Thompson, Richard A.

    1. Database Extraction of Metabolite Information of Drug Candidates: Analysis of 27 AstraZeneca Compounds with Human Absorption, Distribution, Metabolism, and Excretion Data
      You have access
      Database Extraction of Metabolite Information of Drug Candidates: Analysis of 27 AstraZeneca Compounds with Human Absorption, Distribution, Metabolism, and Excretion Data
      Jessica Iegre, Martin A. Hayes, Richard A. Thompson, Lars Weidolf and Emre M. Isin
      Drug Metabolism and Disposition May 2016, 44 (5) 732-740; DOI: https://doi.org/10.1124/dmd.115.067850
  3. Tracy, Timothy S.

    1. You have access
      Immobilized Cytochrome P450 for Monitoring of P450-P450 Interactions and Metabolism
      Chris D. Bostick, Katherine M. Hickey, Lance A. Wollenberg, Darcy R. Flora, Timothy S. Tracy and Peter M. Gannett
      Drug Metabolism and Disposition May 2016, 44 (5) 741-749; DOI: https://doi.org/10.1124/dmd.115.067637

U

  1. Unadkat, Jashvant D.

    1. You have access
      RETRACTION: CYP2D6 Is Inducible by Endogenous and Exogenous Corticosteroids
      Muhammad Farooq, Edward J. Kelly and Jashvant D. Unadkat
      Drug Metabolism and Disposition May 2016, 44 (5) 750-757; DOI: https://doi.org/10.1124/dmd.115.069229

V

  1. van Dam, Annie

    1. You have access
      The Consequence of Drug–Drug Interactions Influencing the Interplay between P-Glycoprotein and Cytochrome P450 3a: An Ex Vivo Study with Rat Precision-Cut Intestinal Slices
      Ming Li, Inge A. M. de Graaf, Sanna Siissalo, Marina H. de Jager, Annie van Dam and Geny M. M. Groothuis
      Drug Metabolism and Disposition May 2016, 44 (5) 683-691; DOI: https://doi.org/10.1124/dmd.115.068684
  2. Vargas, Alexandra

    1. You have access
      Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans
      Su-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. Mangold
      Drug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
  3. Varma, Manthena V.

    1. You have access
      The Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced Myopathy
      Heather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447
  4. von Bergen, Martin

    1. You have access
      The ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy Cows
      Hanna Mahnke, Mariana Ballent, Sven Baumann, Fernanda Imperiale, Martin von Bergen, Carlos Lanusse, Adrian L. Lifschitz, Walther Honscha and Sandra Halwachs
      Drug Metabolism and Disposition May 2016, 44 (5) 700-708; DOI: https://doi.org/10.1124/dmd.115.068940

W

  1. Walker, Gregory S.

    1. You have access
      Biosynthesis of Fluorinated Analogs of Drugs Using Human Cytochrome P450 Enzymes Followed by Deoxyfluorination and Quantitative Nuclear Magnetic Resonance Spectroscopy to Improve Metabolic Stability
      R. Scott Obach, Gregory S. Walker and Michael A. Brodney
      Drug Metabolism and Disposition May 2016, 44 (5) 634-646; DOI: https://doi.org/10.1124/dmd.116.069310
  2. Walles, Markus

    1. You have access
      Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
      Eugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. Moore
      Drug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
  3. Wan, Debin

    1. You have access
      Catalytic Activities of Tumor-Specific Human Cytochrome P450 CYP2W1 Toward Endogenous Substrates
      Yan Zhao, Debin Wan, Jun Yang, Bruce D. Hammock and Paul R. Ortiz de Montellano
      Drug Metabolism and Disposition May 2016, 44 (5) 771-780; DOI: https://doi.org/10.1124/dmd.116.069633
  4. Wang, Guangji

    1. You have access
      Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated Apoptosis
      Tingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping Hao
      Drug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
  5. Wang, Hong

    1. You have access
      Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated Apoptosis
      Tingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping Hao
      Drug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
  6. Wang, Lai

    1. You have access
      Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans
      Su-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. Mangold
      Drug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
  7. Wang, Weirong

    1. You have access
      Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
      Eugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. Moore
      Drug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
  8. Wang, Yongtao

    1. You have access
      Schisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in Mice
      Xi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang Bi
      Drug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
  9. Weidolf, Lars

    1. Database Extraction of Metabolite Information of Drug Candidates: Analysis of 27 AstraZeneca Compounds with Human Absorption, Distribution, Metabolism, and Excretion Data
      You have access
      Database Extraction of Metabolite Information of Drug Candidates: Analysis of 27 AstraZeneca Compounds with Human Absorption, Distribution, Metabolism, and Excretion Data
      Jessica Iegre, Martin A. Hayes, Richard A. Thompson, Lars Weidolf and Emre M. Isin
      Drug Metabolism and Disposition May 2016, 44 (5) 732-740; DOI: https://doi.org/10.1124/dmd.115.067850
  10. West, Michael

    1. You have access
      The Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide–Mediated Hepatic Clearance and May Potentiate Statin-Induced Myopathy
      Heather Eng, Renato J. Scialis, Charles J. Rotter, Jian Lin, Sarah Lazzaro, Manthena V. Varma, Li Di, Bo Feng, Michael West and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2016, 44 (5) 692-699; DOI: https://doi.org/10.1124/dmd.115.067447
  11. Wollenberg, Lance A.

    1. You have access
      Immobilized Cytochrome P450 for Monitoring of P450-P450 Interactions and Metabolism
      Chris D. Bostick, Katherine M. Hickey, Lance A. Wollenberg, Darcy R. Flora, Timothy S. Tracy and Peter M. Gannett
      Drug Metabolism and Disposition May 2016, 44 (5) 741-749; DOI: https://doi.org/10.1124/dmd.115.067637
  12. Wonganan, Piynauch

    1. You have access
      Integrin Receptors Play a Key Role in the Regulation of Hepatic CYP3A
      Kristina Jonsson-Schmunk, Piynauch Wonganan, Jin Huk Choi, Shellie M. Callahan and Maria A. Croyle
      Drug Metabolism and Disposition May 2016, 44 (5) 758-770; DOI: https://doi.org/10.1124/dmd.115.068874
  13. Wu, Yuzheng

    1. You have access
      Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated Apoptosis
      Tingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping Hao
      Drug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419

X

  1. Xiao, Guangqing

    1. You have access
      Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
      Eugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. Moore
      Drug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
  2. Xie, Cen

    1. You have access
      Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated Apoptosis
      Tingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping Hao
      Drug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419

Y

  1. Yagai, Tomoki

    1. You have access
      Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated Apoptosis
      Tingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping Hao
      Drug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
  2. Yan, Tingting

    1. You have access
      Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated Apoptosis
      Tingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping Hao
      Drug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
  3. Yang, Fan

    1. You have access
      KAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male Subjects
      Su-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. Stein
      Drug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
  4. Yang, Johnny J.

    1. You have access
      Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
      Eugenia Kraynov, Amrita V. Kamath, Markus Walles, Edit Tarcsa, Antoine Deslandes, Ramaswamy A. Iyer, Amita Datta-Mannan, Priya Sriraman, Michaela Bairlein, Johnny J. Yang, Matthew Barfield, Guangqing Xiao, Enrique Escandon, Weirong Wang, Dan A. Rock, Nagendra V. Chemuturi and David J. Moore
      Drug Metabolism and Disposition May 2016, 44 (5) 617-623; DOI: https://doi.org/10.1124/dmd.115.068049
  5. Yang, Jun

    1. You have access
      Catalytic Activities of Tumor-Specific Human Cytochrome P450 CYP2W1 Toward Endogenous Substrates
      Yan Zhao, Debin Wan, Jun Yang, Bruce D. Hammock and Paul R. Ortiz de Montellano
      Drug Metabolism and Disposition May 2016, 44 (5) 771-780; DOI: https://doi.org/10.1124/dmd.116.069633
  6. Yang, Ziping

    1. You have access
      KAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male Subjects
      Su-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. Stein
      Drug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187

Z

  1. Zeng, Hang

    1. You have access
      Schisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in Mice
      Xi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang Bi
      Drug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
  2. Zeng, Xuezhen

    1. You have access
      Schisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in Mice
      Xi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang Bi
      Drug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
  3. Zhang, Jin

    1. You have access
      Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans
      Su-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. Mangold
      Drug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
  4. Zhang, Jun

    1. You have access
      Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated Apoptosis
      Tingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping Hao
      Drug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
  5. Zhao, Min

    1. You have access
      Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated Apoptosis
      Tingting Yan, Hong Wang, Min Zhao, Tomoki Yagai, Yingying Chai, Kristopher W. Krausz, Cen Xie, Xuefang Cheng, Jun Zhang, Yuan Che, Feiyan Li, Yuzheng Wu, Chad N. Brocker, Frank J. Gonzalez, Guangji Wang and Haiping Hao
      Drug Metabolism and Disposition May 2016, 44 (5) 720-731; DOI: https://doi.org/10.1124/dmd.116.069419
  6. Zhao, Yan

    1. You have access
      Catalytic Activities of Tumor-Specific Human Cytochrome P450 CYP2W1 Toward Endogenous Substrates
      Yan Zhao, Debin Wan, Jun Yang, Bruce D. Hammock and Paul R. Ortiz de Montellano
      Drug Metabolism and Disposition May 2016, 44 (5) 771-780; DOI: https://doi.org/10.1124/dmd.116.069633
  7. Zhou, Yawen

    1. You have access
      Schisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in Mice
      Xi Li, Xiaomei Fan, Dongshun Li, Xuezhen Zeng, Hang Zeng, Yongtao Wang, Yawen Zhou, Yixin Chen, Min Huang and Huichang Bi
      Drug Metabolism and Disposition May 2016, 44 (5) 647-652; DOI: https://doi.org/10.1124/dmd.115.068288
  8. Zhu, Chun-qi

    1. You have access
      KAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male Subjects
      Su-Er W. Huskey, Chun-qi Zhu, Andreas Fredenhagen, Jürgen Kühnöl, Alexandre Luneau, Zhigang Jian, Ziping Yang, Zhuang Miao, Fan Yang, Jay P. Jain, Gangadhar Sunkara, James B. Mangold and Daniel S. Stein
      Drug Metabolism and Disposition May 2016, 44 (5) 672-682; DOI: https://doi.org/10.1124/dmd.115.069187
    2. You have access
      Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans
      Su-Er W. Huskey, Chun-qi Zhu, Melissa M. Lin, Ry R. Forseth, Helen Gu, Oliver Simon, Fabian K. Eggimann, Matthias Kittelmann, Alexandre Luneau, Alexandra Vargas, Hongmei Li, Lai Wang, Heidi J. Einolf, Jin Zhang, Sarah Favara, Handan He and James B. Mangold
      Drug Metabolism and Disposition May 2016, 44 (5) 653-664; DOI: https://doi.org/10.1124/dmd.115.069112
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Drug Metabolism and Disposition: 44 (5)
Drug Metabolism and Disposition
Vol. 44, Issue 5
1 May 2016
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