Table of Contents

Articles

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  Effect of Rifampin on the Disposition of Brivaracetam in Human Subjects: Further Insights into Brivaracetam Hydrolysis

  Armel Stockis, Shikiko Watanabe, André J. Scheen, Dominique Tytgat, Brigitte Gerin, Maria Rosa, Hugues Chanteux and Jean-Marie Nicolas

  Drug Metabolism and Disposition June 2016, 44 (6) 792-799; DOI: https://doi.org/10.1124/dmd.115.069161
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  An Integrated Approach for Studying Exposure, Metabolism, and Disposition of Multiple Component Herbal Medicines Using High-Resolution Mass Spectrometry and Multiple Data Processing Tools

  Caisheng Wu, Haiying Zhang, Caihong Wang, Hailin Qin, Mingshe Zhu and Jinlan Zhang

  Drug Metabolism and Disposition June 2016, 44 (6) 800-808; DOI: https://doi.org/10.1124/dmd.115.068189
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  Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement

  Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson

  Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866
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  Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model

  Lisa M. Almond, Sophie Mukadam, Iain Gardner, Krystle Okialda, Susan Wong, Oliver Hatley, Suzanne Tay, Karen Rowland-Yeo, Masoud Jamei, Amin Rostami-Hodjegan and Jane R. Kenny

  Drug Metabolism and Disposition June 2016, 44 (6) 821-832; DOI: https://doi.org/10.1124/dmd.115.066845
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  A New Marmoset P450 4F12 Enzyme Expressed in Small Intestines and Livers Efficiently Metabolizes Antihistaminic Drug Ebastine

  Shotaro Uehara, Yasuhiro Uno, Yukako Yuki, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki

  Drug Metabolism and Disposition June 2016, 44 (6) 833-841; DOI: https://doi.org/10.1124/dmd.116.070367
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  RNA Sequencing Quantification of Xenobiotic-Processing Genes in Various Sections of the Intestine in Comparison to the Liver of Male Mice

  Zidong Donna Fu, Felcy Pavithra Selwyn, Julia Yue Cui and Curtis D. Klaassen

  Drug Metabolism and Disposition June 2016, 44 (6) 842-856; DOI: https://doi.org/10.1124/dmd.115.068270
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  Cysteinyl Leukotriene Receptor 1/2 Antagonists Nonselectively Modulate Organic Anion Transport by Multidrug Resistance Proteins (MRP1-4)

  Mark A. Csandl, Gwenaëlle Conseil and Susan P. C. Cole

  Drug Metabolism and Disposition June 2016, 44 (6) 857-866; DOI: https://doi.org/10.1124/dmd.116.069468
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  p38 MAP Kinase Links CAR Activation and Inactivation in the Nucleus via Phosphorylation at Threonine 38

  Takeshi Hori, Rick Moore and Masahiko Negishi

  Drug Metabolism and Disposition June 2016, 44 (6) 871-876; DOI: https://doi.org/10.1124/dmd.116.070235