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Index by author

June 01, 2016; Volume 44,Issue 6

A

  1. Almond, Lisa M.

    1. Open Access
      Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model
      Lisa M. Almond, Sophie Mukadam, Iain Gardner, Krystle Okialda, Susan Wong, Oliver Hatley, Suzanne Tay, Karen Rowland-Yeo, Masoud Jamei, Amin Rostami-Hodjegan and Jane R. Kenny
      Drug Metabolism and Disposition June 2016, 44 (6) 821-832; DOI: https://doi.org/10.1124/dmd.115.066845

B

  1. Belema, Makonen

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

  2. Brock, William J.

    1. Hepatocellular Disposition and Transporter Interactions with Tolvaptan and Metabolites in Sandwich-Cultured Human Hepatocytes
      Yang Lu, Jason R. Slizgi, Kenneth R. Brouwer, Robert L. St. Claire, Kimberly M. Freeman, Maxwell Pan, William J. Brock and Kim L. R. Brouwer
      Drug Metabolism and Disposition June 2016, 44 (6) 867-870; DOI: https://doi.org/10.1124/dmd.115.067629

  3. Brouwer, Kenneth R.

    1. Hepatocellular Disposition and Transporter Interactions with Tolvaptan and Metabolites in Sandwich-Cultured Human Hepatocytes
      Yang Lu, Jason R. Slizgi, Kenneth R. Brouwer, Robert L. St. Claire, Kimberly M. Freeman, Maxwell Pan, William J. Brock and Kim L. R. Brouwer
      Drug Metabolism and Disposition June 2016, 44 (6) 867-870; DOI: https://doi.org/10.1124/dmd.115.067629

  4. Brouwer, Kim L. R.

    1. Hepatocellular Disposition and Transporter Interactions with Tolvaptan and Metabolites in Sandwich-Cultured Human Hepatocytes
      Yang Lu, Jason R. Slizgi, Kenneth R. Brouwer, Robert L. St. Claire, Kimberly M. Freeman, Maxwell Pan, William J. Brock and Kim L. R. Brouwer
      Drug Metabolism and Disposition June 2016, 44 (6) 867-870; DOI: https://doi.org/10.1124/dmd.115.067629

C

  1. Caceres-Cortes, Janet

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

  2. Chang, Shu Y.

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

  3. Chanteux, Hugues

    1. Effect of Rifampin on the Disposition of Brivaracetam in Human Subjects: Further Insights into Brivaracetam Hydrolysis
      Armel Stockis, Shikiko Watanabe, André J. Scheen, Dominique Tytgat, Brigitte Gerin, Maria Rosa, Hugues Chanteux and Jean-Marie Nicolas
      Drug Metabolism and Disposition June 2016, 44 (6) 792-799; DOI: https://doi.org/10.1124/dmd.115.069161

  4. Cole, Susan P. C.

    1. Cysteinyl Leukotriene Receptor 1/2 Antagonists Nonselectively Modulate Organic Anion Transport by Multidrug Resistance Proteins (MRP1-4)
      Mark A. Csandl, Gwenaëlle Conseil and Susan P. C. Cole
      Drug Metabolism and Disposition June 2016, 44 (6) 857-866; DOI: https://doi.org/10.1124/dmd.116.069468

  5. Conseil, Gwenaëlle

    1. Cysteinyl Leukotriene Receptor 1/2 Antagonists Nonselectively Modulate Organic Anion Transport by Multidrug Resistance Proteins (MRP1-4)
      Mark A. Csandl, Gwenaëlle Conseil and Susan P. C. Cole
      Drug Metabolism and Disposition June 2016, 44 (6) 857-866; DOI: https://doi.org/10.1124/dmd.116.069468

  6. Csandl, Mark A.

    1. Cysteinyl Leukotriene Receptor 1/2 Antagonists Nonselectively Modulate Organic Anion Transport by Multidrug Resistance Proteins (MRP1-4)
      Mark A. Csandl, Gwenaëlle Conseil and Susan P. C. Cole
      Drug Metabolism and Disposition June 2016, 44 (6) 857-866; DOI: https://doi.org/10.1124/dmd.116.069468

  7. Cui, Julia Yue

    1. RNA Sequencing Quantification of Xenobiotic-Processing Genes in Various Sections of the Intestine in Comparison to the Liver of Male Mice
      Zidong Donna Fu, Felcy Pavithra Selwyn, Julia Yue Cui and Curtis D. Klaassen
      Drug Metabolism and Disposition June 2016, 44 (6) 842-856; DOI: https://doi.org/10.1124/dmd.115.068270

E

  1. Easter, John

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

F

  1. Fancher, R. Marcus

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

  2. Freeman, Kimberly M.

    1. Hepatocellular Disposition and Transporter Interactions with Tolvaptan and Metabolites in Sandwich-Cultured Human Hepatocytes
      Yang Lu, Jason R. Slizgi, Kenneth R. Brouwer, Robert L. St. Claire, Kimberly M. Freeman, Maxwell Pan, William J. Brock and Kim L. R. Brouwer
      Drug Metabolism and Disposition June 2016, 44 (6) 867-870; DOI: https://doi.org/10.1124/dmd.115.067629

  3. Fu, Zidong Donna

    1. RNA Sequencing Quantification of Xenobiotic-Processing Genes in Various Sections of the Intestine in Comparison to the Liver of Male Mice
      Zidong Donna Fu, Felcy Pavithra Selwyn, Julia Yue Cui and Curtis D. Klaassen
      Drug Metabolism and Disposition June 2016, 44 (6) 842-856; DOI: https://doi.org/10.1124/dmd.115.068270

G

  1. Gao, Min

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

  2. Gardner, Iain

    1. Open Access
      Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model
      Lisa M. Almond, Sophie Mukadam, Iain Gardner, Krystle Okialda, Susan Wong, Oliver Hatley, Suzanne Tay, Karen Rowland-Yeo, Masoud Jamei, Amin Rostami-Hodjegan and Jane R. Kenny
      Drug Metabolism and Disposition June 2016, 44 (6) 821-832; DOI: https://doi.org/10.1124/dmd.115.066845

  3. Gerin, Brigitte

    1. Effect of Rifampin on the Disposition of Brivaracetam in Human Subjects: Further Insights into Brivaracetam Hydrolysis
      Armel Stockis, Shikiko Watanabe, André J. Scheen, Dominique Tytgat, Brigitte Gerin, Maria Rosa, Hugues Chanteux and Jean-Marie Nicolas
      Drug Metabolism and Disposition June 2016, 44 (6) 792-799; DOI: https://doi.org/10.1124/dmd.115.069161

  4. Goodrich, Jason

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

H

  1. Hamann, Lawrence G.

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

  2. Hatley, Oliver

    1. Open Access
      Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model
      Lisa M. Almond, Sophie Mukadam, Iain Gardner, Krystle Okialda, Susan Wong, Oliver Hatley, Suzanne Tay, Karen Rowland-Yeo, Masoud Jamei, Amin Rostami-Hodjegan and Jane R. Kenny
      Drug Metabolism and Disposition June 2016, 44 (6) 821-832; DOI: https://doi.org/10.1124/dmd.115.066845

  3. Hong, Yang

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

  4. Hori, Takeshi

    1. p38 MAP Kinase Links CAR Activation and Inactivation in the Nucleus via Phosphorylation at Threonine 38
      p38 MAP Kinase Links CAR Activation and Inactivation in the Nucleus via Phosphorylation at Threonine 38
      Takeshi Hori, Rick Moore and Masahiko Negishi
      Drug Metabolism and Disposition June 2016, 44 (6) 871-876; DOI: https://doi.org/10.1124/dmd.116.070235

  5. Huang, Xiaohua

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

  6. Humphreys, W. Griffith

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

I

  1. Inoue, Takashi

    1. A New Marmoset P450 4F12 Enzyme Expressed in Small Intestines and Livers Efficiently Metabolizes Antihistaminic Drug Ebastine
      A New Marmoset P450 4F12 Enzyme Expressed in Small Intestines and Livers Efficiently Metabolizes Antihistaminic Drug Ebastine
      Shotaro Uehara, Yasuhiro Uno, Yukako Yuki, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition June 2016, 44 (6) 833-841; DOI: https://doi.org/10.1124/dmd.116.070367

J

  1. Jamei, Masoud

    1. Open Access
      Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model
      Lisa M. Almond, Sophie Mukadam, Iain Gardner, Krystle Okialda, Susan Wong, Oliver Hatley, Suzanne Tay, Karen Rowland-Yeo, Masoud Jamei, Amin Rostami-Hodjegan and Jane R. Kenny
      Drug Metabolism and Disposition June 2016, 44 (6) 821-832; DOI: https://doi.org/10.1124/dmd.115.066845

  2. Johnson, Benjamin M.

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

K

  1. Kenny, Jane R.

    1. Open Access
      Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model
      Lisa M. Almond, Sophie Mukadam, Iain Gardner, Krystle Okialda, Susan Wong, Oliver Hatley, Suzanne Tay, Karen Rowland-Yeo, Masoud Jamei, Amin Rostami-Hodjegan and Jane R. Kenny
      Drug Metabolism and Disposition June 2016, 44 (6) 821-832; DOI: https://doi.org/10.1124/dmd.115.066845

  2. Klaassen, Curtis D.

    1. RNA Sequencing Quantification of Xenobiotic-Processing Genes in Various Sections of the Intestine in Comparison to the Liver of Male Mice
      Zidong Donna Fu, Felcy Pavithra Selwyn, Julia Yue Cui and Curtis D. Klaassen
      Drug Metabolism and Disposition June 2016, 44 (6) 842-856; DOI: https://doi.org/10.1124/dmd.115.068270

L

  1. Leet, John E.

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

  2. Li, Wenying

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

  3. Liu, Xiaohong

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

  4. Lopez, Omar D.

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

  5. Lu, Yang

    1. Hepatocellular Disposition and Transporter Interactions with Tolvaptan and Metabolites in Sandwich-Cultured Human Hepatocytes
      Yang Lu, Jason R. Slizgi, Kenneth R. Brouwer, Robert L. St. Claire, Kimberly M. Freeman, Maxwell Pan, William J. Brock and Kim L. R. Brouwer
      Drug Metabolism and Disposition June 2016, 44 (6) 867-870; DOI: https://doi.org/10.1124/dmd.115.067629

M

  1. Ma, Li

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

  2. Moore, Rick

    1. p38 MAP Kinase Links CAR Activation and Inactivation in the Nucleus via Phosphorylation at Threonine 38
      p38 MAP Kinase Links CAR Activation and Inactivation in the Nucleus via Phosphorylation at Threonine 38
      Takeshi Hori, Rick Moore and Masahiko Negishi
      Drug Metabolism and Disposition June 2016, 44 (6) 871-876; DOI: https://doi.org/10.1124/dmd.116.070235

  3. Mukadam, Sophie

    1. Open Access
      Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model
      Lisa M. Almond, Sophie Mukadam, Iain Gardner, Krystle Okialda, Susan Wong, Oliver Hatley, Suzanne Tay, Karen Rowland-Yeo, Masoud Jamei, Amin Rostami-Hodjegan and Jane R. Kenny
      Drug Metabolism and Disposition June 2016, 44 (6) 821-832; DOI: https://doi.org/10.1124/dmd.115.066845

N

  1. Negishi, Masahiko

    1. p38 MAP Kinase Links CAR Activation and Inactivation in the Nucleus via Phosphorylation at Threonine 38
      p38 MAP Kinase Links CAR Activation and Inactivation in the Nucleus via Phosphorylation at Threonine 38
      Takeshi Hori, Rick Moore and Masahiko Negishi
      Drug Metabolism and Disposition June 2016, 44 (6) 871-876; DOI: https://doi.org/10.1124/dmd.116.070235

  2. Nguyen, Van

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

  3. Nicolas, Jean-Marie

    1. Effect of Rifampin on the Disposition of Brivaracetam in Human Subjects: Further Insights into Brivaracetam Hydrolysis
      Armel Stockis, Shikiko Watanabe, André J. Scheen, Dominique Tytgat, Brigitte Gerin, Maria Rosa, Hugues Chanteux and Jean-Marie Nicolas
      Drug Metabolism and Disposition June 2016, 44 (6) 792-799; DOI: https://doi.org/10.1124/dmd.115.069161

O

  1. Okialda, Krystle

    1. Open Access
      Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model
      Lisa M. Almond, Sophie Mukadam, Iain Gardner, Krystle Okialda, Susan Wong, Oliver Hatley, Suzanne Tay, Karen Rowland-Yeo, Masoud Jamei, Amin Rostami-Hodjegan and Jane R. Kenny
      Drug Metabolism and Disposition June 2016, 44 (6) 821-832; DOI: https://doi.org/10.1124/dmd.115.066845

P

  1. Pan, Maxwell

    1. Hepatocellular Disposition and Transporter Interactions with Tolvaptan and Metabolites in Sandwich-Cultured Human Hepatocytes
      Yang Lu, Jason R. Slizgi, Kenneth R. Brouwer, Robert L. St. Claire, Kimberly M. Freeman, Maxwell Pan, William J. Brock and Kim L. R. Brouwer
      Drug Metabolism and Disposition June 2016, 44 (6) 867-870; DOI: https://doi.org/10.1124/dmd.115.067629

Q

  1. Qin, Hailin

    1. An Integrated Approach for Studying Exposure, Metabolism, and Disposition of Multiple Component Herbal Medicines Using High-Resolution Mass Spectrometry and Multiple Data Processing Tools
      Caisheng Wu, Haiying Zhang, Caihong Wang, Hailin Qin, Mingshe Zhu and Jinlan Zhang
      Drug Metabolism and Disposition June 2016, 44 (6) 800-808; DOI: https://doi.org/10.1124/dmd.115.068189

R

  1. Rosa, Maria

    1. Effect of Rifampin on the Disposition of Brivaracetam in Human Subjects: Further Insights into Brivaracetam Hydrolysis
      Armel Stockis, Shikiko Watanabe, André J. Scheen, Dominique Tytgat, Brigitte Gerin, Maria Rosa, Hugues Chanteux and Jean-Marie Nicolas
      Drug Metabolism and Disposition June 2016, 44 (6) 792-799; DOI: https://doi.org/10.1124/dmd.115.069161

  2. Rostami-Hodjegan, Amin

    1. Open Access
      Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model
      Lisa M. Almond, Sophie Mukadam, Iain Gardner, Krystle Okialda, Susan Wong, Oliver Hatley, Suzanne Tay, Karen Rowland-Yeo, Masoud Jamei, Amin Rostami-Hodjegan and Jane R. Kenny
      Drug Metabolism and Disposition June 2016, 44 (6) 821-832; DOI: https://doi.org/10.1124/dmd.115.066845

  3. Rowland-Yeo, Karen

    1. Open Access
      Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model
      Lisa M. Almond, Sophie Mukadam, Iain Gardner, Krystle Okialda, Susan Wong, Oliver Hatley, Suzanne Tay, Karen Rowland-Yeo, Masoud Jamei, Amin Rostami-Hodjegan and Jane R. Kenny
      Drug Metabolism and Disposition June 2016, 44 (6) 821-832; DOI: https://doi.org/10.1124/dmd.115.066845

S

  1. Sasaki, Erika

    1. A New Marmoset P450 4F12 Enzyme Expressed in Small Intestines and Livers Efficiently Metabolizes Antihistaminic Drug Ebastine
      A New Marmoset P450 4F12 Enzyme Expressed in Small Intestines and Livers Efficiently Metabolizes Antihistaminic Drug Ebastine
      Shotaro Uehara, Yasuhiro Uno, Yukako Yuki, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition June 2016, 44 (6) 833-841; DOI: https://doi.org/10.1124/dmd.116.070367

  2. Scheen, André J.

    1. Effect of Rifampin on the Disposition of Brivaracetam in Human Subjects: Further Insights into Brivaracetam Hydrolysis
      Armel Stockis, Shikiko Watanabe, André J. Scheen, Dominique Tytgat, Brigitte Gerin, Maria Rosa, Hugues Chanteux and Jean-Marie Nicolas
      Drug Metabolism and Disposition June 2016, 44 (6) 792-799; DOI: https://doi.org/10.1124/dmd.115.069161

  3. Selwyn, Felcy Pavithra

    1. RNA Sequencing Quantification of Xenobiotic-Processing Genes in Various Sections of the Intestine in Comparison to the Liver of Male Mice
      Zidong Donna Fu, Felcy Pavithra Selwyn, Julia Yue Cui and Curtis D. Klaassen
      Drug Metabolism and Disposition June 2016, 44 (6) 842-856; DOI: https://doi.org/10.1124/dmd.115.068270

  4. Shu, Yue-Zhong

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

  5. Slizgi, Jason R.

    1. Hepatocellular Disposition and Transporter Interactions with Tolvaptan and Metabolites in Sandwich-Cultured Human Hepatocytes
      Yang Lu, Jason R. Slizgi, Kenneth R. Brouwer, Robert L. St. Claire, Kimberly M. Freeman, Maxwell Pan, William J. Brock and Kim L. R. Brouwer
      Drug Metabolism and Disposition June 2016, 44 (6) 867-870; DOI: https://doi.org/10.1124/dmd.115.067629

  6. St. Claire, Robert L.

    1. Hepatocellular Disposition and Transporter Interactions with Tolvaptan and Metabolites in Sandwich-Cultured Human Hepatocytes
      Yang Lu, Jason R. Slizgi, Kenneth R. Brouwer, Robert L. St. Claire, Kimberly M. Freeman, Maxwell Pan, William J. Brock and Kim L. R. Brouwer
      Drug Metabolism and Disposition June 2016, 44 (6) 867-870; DOI: https://doi.org/10.1124/dmd.115.067629

  7. Stockis, Armel

    1. Effect of Rifampin on the Disposition of Brivaracetam in Human Subjects: Further Insights into Brivaracetam Hydrolysis
      Armel Stockis, Shikiko Watanabe, André J. Scheen, Dominique Tytgat, Brigitte Gerin, Maria Rosa, Hugues Chanteux and Jean-Marie Nicolas
      Drug Metabolism and Disposition June 2016, 44 (6) 792-799; DOI: https://doi.org/10.1124/dmd.115.069161

T

  1. Tay, Suzanne

    1. Open Access
      Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model
      Lisa M. Almond, Sophie Mukadam, Iain Gardner, Krystle Okialda, Susan Wong, Oliver Hatley, Suzanne Tay, Karen Rowland-Yeo, Masoud Jamei, Amin Rostami-Hodjegan and Jane R. Kenny
      Drug Metabolism and Disposition June 2016, 44 (6) 821-832; DOI: https://doi.org/10.1124/dmd.115.066845

  2. Tytgat, Dominique

    1. Effect of Rifampin on the Disposition of Brivaracetam in Human Subjects: Further Insights into Brivaracetam Hydrolysis
      Armel Stockis, Shikiko Watanabe, André J. Scheen, Dominique Tytgat, Brigitte Gerin, Maria Rosa, Hugues Chanteux and Jean-Marie Nicolas
      Drug Metabolism and Disposition June 2016, 44 (6) 792-799; DOI: https://doi.org/10.1124/dmd.115.069161

U

  1. Uehara, Shotaro

    1. A New Marmoset P450 4F12 Enzyme Expressed in Small Intestines and Livers Efficiently Metabolizes Antihistaminic Drug Ebastine
      A New Marmoset P450 4F12 Enzyme Expressed in Small Intestines and Livers Efficiently Metabolizes Antihistaminic Drug Ebastine
      Shotaro Uehara, Yasuhiro Uno, Yukako Yuki, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition June 2016, 44 (6) 833-841; DOI: https://doi.org/10.1124/dmd.116.070367

  2. Uno, Yasuhiro

    1. A New Marmoset P450 4F12 Enzyme Expressed in Small Intestines and Livers Efficiently Metabolizes Antihistaminic Drug Ebastine
      A New Marmoset P450 4F12 Enzyme Expressed in Small Intestines and Livers Efficiently Metabolizes Antihistaminic Drug Ebastine
      Shotaro Uehara, Yasuhiro Uno, Yukako Yuki, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition June 2016, 44 (6) 833-841; DOI: https://doi.org/10.1124/dmd.116.070367

W

  1. Wang, Caihong

    1. An Integrated Approach for Studying Exposure, Metabolism, and Disposition of Multiple Component Herbal Medicines Using High-Resolution Mass Spectrometry and Multiple Data Processing Tools
      Caisheng Wu, Haiying Zhang, Caihong Wang, Hailin Qin, Mingshe Zhu and Jinlan Zhang
      Drug Metabolism and Disposition June 2016, 44 (6) 800-808; DOI: https://doi.org/10.1124/dmd.115.068189

  2. Watanabe, Shikiko

    1. Effect of Rifampin on the Disposition of Brivaracetam in Human Subjects: Further Insights into Brivaracetam Hydrolysis
      Armel Stockis, Shikiko Watanabe, André J. Scheen, Dominique Tytgat, Brigitte Gerin, Maria Rosa, Hugues Chanteux and Jean-Marie Nicolas
      Drug Metabolism and Disposition June 2016, 44 (6) 792-799; DOI: https://doi.org/10.1124/dmd.115.069161

  3. Wong, Susan

    1. Open Access
      Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model
      Lisa M. Almond, Sophie Mukadam, Iain Gardner, Krystle Okialda, Susan Wong, Oliver Hatley, Suzanne Tay, Karen Rowland-Yeo, Masoud Jamei, Amin Rostami-Hodjegan and Jane R. Kenny
      Drug Metabolism and Disposition June 2016, 44 (6) 821-832; DOI: https://doi.org/10.1124/dmd.115.066845

  4. Wu, Caisheng

    1. An Integrated Approach for Studying Exposure, Metabolism, and Disposition of Multiple Component Herbal Medicines Using High-Resolution Mass Spectrometry and Multiple Data Processing Tools
      Caisheng Wu, Haiying Zhang, Caihong Wang, Hailin Qin, Mingshe Zhu and Jinlan Zhang
      Drug Metabolism and Disposition June 2016, 44 (6) 800-808; DOI: https://doi.org/10.1124/dmd.115.068189

Y

  1. Yamazaki, Hiroshi

    1. A New Marmoset P450 4F12 Enzyme Expressed in Small Intestines and Livers Efficiently Metabolizes Antihistaminic Drug Ebastine
      A New Marmoset P450 4F12 Enzyme Expressed in Small Intestines and Livers Efficiently Metabolizes Antihistaminic Drug Ebastine
      Shotaro Uehara, Yasuhiro Uno, Yukako Yuki, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition June 2016, 44 (6) 833-841; DOI: https://doi.org/10.1124/dmd.116.070367

  2. Yuki, Yukako

    1. A New Marmoset P450 4F12 Enzyme Expressed in Small Intestines and Livers Efficiently Metabolizes Antihistaminic Drug Ebastine
      A New Marmoset P450 4F12 Enzyme Expressed in Small Intestines and Livers Efficiently Metabolizes Antihistaminic Drug Ebastine
      Shotaro Uehara, Yasuhiro Uno, Yukako Yuki, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition June 2016, 44 (6) 833-841; DOI: https://doi.org/10.1124/dmd.116.070367

Z

  1. Zhang, Haiying

    1. An Integrated Approach for Studying Exposure, Metabolism, and Disposition of Multiple Component Herbal Medicines Using High-Resolution Mass Spectrometry and Multiple Data Processing Tools
      Caisheng Wu, Haiying Zhang, Caihong Wang, Hailin Qin, Mingshe Zhu and Jinlan Zhang
      Drug Metabolism and Disposition June 2016, 44 (6) 800-808; DOI: https://doi.org/10.1124/dmd.115.068189

  2. Zhang, Jinlan

    1. An Integrated Approach for Studying Exposure, Metabolism, and Disposition of Multiple Component Herbal Medicines Using High-Resolution Mass Spectrometry and Multiple Data Processing Tools
      Caisheng Wu, Haiying Zhang, Caihong Wang, Hailin Qin, Mingshe Zhu and Jinlan Zhang
      Drug Metabolism and Disposition June 2016, 44 (6) 800-808; DOI: https://doi.org/10.1124/dmd.115.068189

  3. Zhao, Weiping

    1. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866

  4. Zhu, Mingshe

    1. An Integrated Approach for Studying Exposure, Metabolism, and Disposition of Multiple Component Herbal Medicines Using High-Resolution Mass Spectrometry and Multiple Data Processing Tools
      Caisheng Wu, Haiying Zhang, Caihong Wang, Hailin Qin, Mingshe Zhu and Jinlan Zhang
      Drug Metabolism and Disposition June 2016, 44 (6) 800-808; DOI: https://doi.org/10.1124/dmd.115.068189
    2. Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine <em>δ</em>-Oxidation and Rearrangement
      Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
      Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D. Lopez, John E. Leet, R. Marcus Fancher, Van Nguyen, Jason Goodrich, John Easter, Yang Hong, Janet Caceres-Cortes, Shu Y. Chang, Li Ma, Makonen Belema, Lawrence G. Hamann, Min Gao, Mingshe Zhu, Yue-Zhong Shu, W. Griffith Humphreys and Benjamin M. Johnson
      Drug Metabolism and Disposition June 2016, 44 (6) 809-820; DOI: https://doi.org/10.1124/dmd.115.068866
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