Research ArticleArticle
An Integrated Approach for Studying Exposure, Metabolism, and Disposition of Multiple Component Herbal Medicines Using High-Resolution Mass Spectrometry and Multiple Data Processing Tools
Caisheng Wu, Haiying Zhang, Caihong Wang, Hailin Qin, Mingshe Zhu and Jinlan Zhang
Drug Metabolism and Disposition June 2016, 44 (6) 800-808; DOI: https://doi.org/10.1124/dmd.115.068189
Caisheng Wu
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (C.Wu., C.Wa., H.Q., J.Z.); Department of Biotransformation, Bristol-Myers Squibb Company, Princeton, New Jersey (H.Z., M.Z.)
Haiying Zhang
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (C.Wu., C.Wa., H.Q., J.Z.); Department of Biotransformation, Bristol-Myers Squibb Company, Princeton, New Jersey (H.Z., M.Z.)
Caihong Wang
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (C.Wu., C.Wa., H.Q., J.Z.); Department of Biotransformation, Bristol-Myers Squibb Company, Princeton, New Jersey (H.Z., M.Z.)
Hailin Qin
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (C.Wu., C.Wa., H.Q., J.Z.); Department of Biotransformation, Bristol-Myers Squibb Company, Princeton, New Jersey (H.Z., M.Z.)
Mingshe Zhu
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (C.Wu., C.Wa., H.Q., J.Z.); Department of Biotransformation, Bristol-Myers Squibb Company, Princeton, New Jersey (H.Z., M.Z.)
Jinlan Zhang
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (C.Wu., C.Wa., H.Q., J.Z.); Department of Biotransformation, Bristol-Myers Squibb Company, Princeton, New Jersey (H.Z., M.Z.)
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ADME of TCM Components by HRMS and Data Processing
Caisheng Wu, Haiying Zhang, Caihong Wang, Hailin Qin, Mingshe Zhu and Jinlan Zhang
Drug Metabolism and Disposition June 1, 2016, 44 (6) 800-808; DOI: https://doi.org/10.1124/dmd.115.068189
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