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Drug Metabolism & Disposition

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    • Current Issue
    • Fast Forward
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Index by author

July 01, 2016; Volume 44,Issue 7
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Abduljalil, Khaled

    1. You have access
      Considering Age Variation When Coining Drugs as High versus Low Hepatic Extraction Ratio
      Farzaneh Salem, Khaled Abduljalil, Yoshiteru Kamiyama and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition July 2016, 44 (7) 1099-1102; DOI: https://doi.org/10.1124/dmd.115.067595
  2. Akai, Sho

    1. You have access
      Zomepirac Acyl Glucuronide Is Responsible for Zomepirac-Induced Acute Kidney Injury in Mice
      Atsushi Iwamura, Katsuhito Watanabe, Sho Akai, Tsubasa Nishinosono, Koichi Tsuneyama, Shingo Oda, Toshiyuki Kume and Tsuyoshi Yokoi
      Drug Metabolism and Disposition July 2016, 44 (7) 888-896; DOI: https://doi.org/10.1124/dmd.116.069575
  3. Aleksunes, Lauren M.

    1. You have access
      Correlation between Conjugated Bisphenol A Concentrations and Efflux Transporter Expression in Human Fetal Livers
      Jamie E. Moscovitz, Muna S. Nahar, Stuart L. Shalat, Angela L. Slitt, Dana C. Dolinoy and Lauren M. Aleksunes
      Drug Metabolism and Disposition July 2016, 44 (7) 1061-1065; DOI: https://doi.org/10.1124/dmd.115.068668
  4. Anderson, Lindsey N.

    1. Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development
      You have access
      Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development
      Natalie C. Sadler, Premchendar Nandhikonda, Bobbie-Jo Webb-Robertson, Charles Ansong, Lindsey N. Anderson, Jordan N. Smith, Richard A. Corley and Aaron T. Wright
      Drug Metabolism and Disposition July 2016, 44 (7) 984-991; DOI: https://doi.org/10.1124/dmd.115.068593
  5. Annaert, Pieter

    1. You have access
      Effect of Age on The Hepatocellularity Number for Wistar rats
      Sarinj Fattah, Patrick Augustijns and Pieter Annaert
      Drug Metabolism and Disposition July 2016, 44 (7) 944-947; DOI: https://doi.org/10.1124/dmd.115.066381
  6. Ansong, Charles

    1. Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development
      You have access
      Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development
      Natalie C. Sadler, Premchendar Nandhikonda, Bobbie-Jo Webb-Robertson, Charles Ansong, Lindsey N. Anderson, Jordan N. Smith, Richard A. Corley and Aaron T. Wright
      Drug Metabolism and Disposition July 2016, 44 (7) 984-991; DOI: https://doi.org/10.1124/dmd.115.068593
  7. Augustijns, Patrick

    1. You have access
      Effect of Age on The Hepatocellularity Number for Wistar rats
      Sarinj Fattah, Patrick Augustijns and Pieter Annaert
      Drug Metabolism and Disposition July 2016, 44 (7) 944-947; DOI: https://doi.org/10.1124/dmd.115.066381

B

  1. Barber, Jill

    1. You have access
      Ontogeny of Hepatic Drug Transporters and Relevance to Drugs Used in Pediatrics
      Yasmine Elmorsi, Jill Barber and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition July 2016, 44 (7) 992-998; DOI: https://doi.org/10.1124/dmd.115.067801
  2. Berman, Jacob M.

    1. You have access
      The Ontogeny and Population Variability of Human Hepatic NADPH Dehydrogenase Quinone Oxido-Reductase 1 (NQO1)
      Luc R.A. Rougée, Zoe Riches, Jacob M. Berman and Abby C. Collier
      Drug Metabolism and Disposition July 2016, 44 (7) 967-974; DOI: https://doi.org/10.1124/dmd.115.068650
  3. Bhattaram, Atul

    1. You have access
      Role of Quantitative Clinical Pharmacology in Pediatric Approval and Labeling
      Nitin Mehrotra, Atul Bhattaram, Justin C. Earp, Jeffry Florian, Kevin Krudys, Jee Eun Lee, Joo Yeon Lee, Jiang Liu, Yeruk Mulugeta, Jingyu Yu, Ping Zhao and Vikram Sinha
      Drug Metabolism and Disposition July 2016, 44 (7) 924-933; DOI: https://doi.org/10.1124/dmd.116.069559
  4. Bi, Chengpeng

    1. You have access
      Dynamics of Cytosine Methylation in the Proximal Promoters of CYP3A4 and CYP3A7 in Pediatric and Prenatal Livers
      Carrie A. Vyhlidal, Chengpeng Bi, Shui Qing Ye and J. Steven Leeder
      Drug Metabolism and Disposition July 2016, 44 (7) 1020-1026; DOI: https://doi.org/10.1124/dmd.115.068726
  5. Bilic, Sanela

    1. You have access
      New Insights in Tissue Distribution, Metabolism, and Excretion of [3H]-Labeled Antibody Maytansinoid Conjugates in Female Tumor-Bearing Nude Rats
      Markus Walles, Bettina Rudolph, Thierry Wolf, Julien Bourgailh, Martina Suetterlin, Thomas Moenius, Gisela Peraus, Olivier Heudi, Walid Elbast, Christian Lanshoeft and Sanela Bilic
      Drug Metabolism and Disposition July 2016, 44 (7) 897-910; DOI: https://doi.org/10.1124/dmd.115.069021
  6. Birg, Anna V.

    1. You have access
      Population Pharmacokinetics of Oral Topotecan in Infants and Very Young Children with Brain Tumors Demonstrates a Role of ABCG2 rs4148157 on the Absorption Rate Constant
      Jessica K. Roberts, Anna V. Birg, Tong Lin, Vinay M. Daryani, John C. Panetta, Alberto Broniscer, Giles W. Robinson, Amar J. Gajjar and Clinton F. Stewart
      Drug Metabolism and Disposition July 2016, 44 (7) 1116-1122; DOI: https://doi.org/10.1124/dmd.115.068676
  7. Bourgailh, Julien

    1. You have access
      New Insights in Tissue Distribution, Metabolism, and Excretion of [3H]-Labeled Antibody Maytansinoid Conjugates in Female Tumor-Bearing Nude Rats
      Markus Walles, Bettina Rudolph, Thierry Wolf, Julien Bourgailh, Martina Suetterlin, Thomas Moenius, Gisela Peraus, Olivier Heudi, Walid Elbast, Christian Lanshoeft and Sanela Bilic
      Drug Metabolism and Disposition July 2016, 44 (7) 897-910; DOI: https://doi.org/10.1124/dmd.115.069021
  8. Broniscer, Alberto

    1. You have access
      Population Pharmacokinetics of Oral Topotecan in Infants and Very Young Children with Brain Tumors Demonstrates a Role of ABCG2 rs4148157 on the Absorption Rate Constant
      Jessica K. Roberts, Anna V. Birg, Tong Lin, Vinay M. Daryani, John C. Panetta, Alberto Broniscer, Giles W. Robinson, Amar J. Gajjar and Clinton F. Stewart
      Drug Metabolism and Disposition July 2016, 44 (7) 1116-1122; DOI: https://doi.org/10.1124/dmd.115.068676
  9. Bush, Kevin T.

    1. You have access
      Kidney versus Liver Specification of SLC and ABC Drug Transporters, Tight Junction Molecules, and Biomarkers
      Gleb Martovetsky, Kevin T. Bush and Sanjay K. Nigam
      Drug Metabolism and Disposition July 2016, 44 (7) 1050-1060; DOI: https://doi.org/10.1124/dmd.115.068254

C

  1. Chen, Shu

    1. You have access
      Metabolite Kinetics: The Segregated Flow Model for Intestinal and Whole Body Physiologically Based Pharmacokinetic Modeling to Describe Intestinal and Hepatic Glucuronidation of Morphine in Rats In Vivo
      Qi Joy Yang, Jianghong Fan, Shu Chen, Lutan Liu, Huadong Sun and K. Sandy Pang
      Drug Metabolism and Disposition July 2016, 44 (7) 1123-1138; DOI: https://doi.org/10.1124/dmd.116.069542
  2. Chen, Yao

    1. You have access
      Quantification of Flavin-containing Monooxygenases 1, 3, and 5 in Human Liver Microsomes by UPLC-MRM-Based Targeted Quantitative Proteomics and Its Application to the Study of Ontogeny
      Yao Chen, Nicole R. Zane, Dhiren R. Thakker and Michael Zhuo Wang
      Drug Metabolism and Disposition July 2016, 44 (7) 975-983; DOI: https://doi.org/10.1124/dmd.115.067538
  3. Collier, Abby C.

    1. You have access
      The Ontogeny and Population Variability of Human Hepatic NADPH Dehydrogenase Quinone Oxido-Reductase 1 (NQO1)
      Luc R.A. Rougée, Zoe Riches, Jacob M. Berman and Abby C. Collier
      Drug Metabolism and Disposition July 2016, 44 (7) 967-974; DOI: https://doi.org/10.1124/dmd.115.068650
  4. Corley, Richard A.

    1. Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development
      You have access
      Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development
      Natalie C. Sadler, Premchendar Nandhikonda, Bobbie-Jo Webb-Robertson, Charles Ansong, Lindsey N. Anderson, Jordan N. Smith, Richard A. Corley and Aaron T. Wright
      Drug Metabolism and Disposition July 2016, 44 (7) 984-991; DOI: https://doi.org/10.1124/dmd.115.068593
  5. Cui, Julia Yue

    1. You have access
      Age-Specific Regulation of Drug-Processing Genes in Mouse Liver by Ligands of Xenobiotic-Sensing Transcription Factors
      Cindy Yanfei Li, Helen J. Renaud, Curtis D. Klaassen and Julia Yue Cui
      Drug Metabolism and Disposition July 2016, 44 (7) 1038-1049; DOI: https://doi.org/10.1124/dmd.115.066639

D

  1. Dai, Hongying

    1. You have access
      Developmental Expression of CYP2B6: A Comprehensive Analysis of mRNA Expression, Protein Content and Bupropion Hydroxylase Activity and the Impact of Genetic Variation
      Robin E. Pearce, Roger Gaedigk, Greyson P. Twist, Hongying Dai, Amanda K. Riffel, J. Steven Leeder and Andrea Gaedigk
      Drug Metabolism and Disposition July 2016, 44 (7) 948-958; DOI: https://doi.org/10.1124/dmd.115.067546
  2. Daniel, James

    1. Open Access
      Decreased Pregnane X Receptor Expression in Children with Active Crohn’s Disease
      Valentina Shakhnovich, Carrie Vyhlidal, Craig Friesen, Amber Hildreth, Vivekanand Singh, James Daniel, Gregory L. Kearns and J. Steven Leeder
      Drug Metabolism and Disposition July 2016, 44 (7) 1066-1069; DOI: https://doi.org/10.1124/dmd.115.068742
  3. Daryani, Vinay M.

    1. You have access
      Population Pharmacokinetics of Oral Topotecan in Infants and Very Young Children with Brain Tumors Demonstrates a Role of ABCG2 rs4148157 on the Absorption Rate Constant
      Jessica K. Roberts, Anna V. Birg, Tong Lin, Vinay M. Daryani, John C. Panetta, Alberto Broniscer, Giles W. Robinson, Amar J. Gajjar and Clinton F. Stewart
      Drug Metabolism and Disposition July 2016, 44 (7) 1116-1122; DOI: https://doi.org/10.1124/dmd.115.068676
  4. de Koning, Barbara A.E.

    1. You have access
      Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life
      Miriam G. Mooij, Evita van de Steeg, Joost van Rosmalen, Jonathan D. Windster, Barbara A.E. de Koning, Wouter H. J. Vaes, Bianca D. van Groen, Dick Tibboel, Heleen M. Wortelboer and Saskia N. de Wildt
      Drug Metabolism and Disposition July 2016, 44 (7) 1005-1013; DOI: https://doi.org/10.1124/dmd.115.068577
  5. de Koning, Barbara E. A.

    1. You have access
      Human Intestinal PEPT1 Transporter Expression and Localization in Preterm and Term Infants
      Miriam G. Mooij, Barbara E. A. de Koning, Dicky J. Lindenbergh-Kortleve, Ytje Simons-Oosterhuis, Bianca D. van Groen, Dick Tibboel, Janneke N. Samsom and Saskia N. de Wildt
      Drug Metabolism and Disposition July 2016, 44 (7) 1014-1019; DOI: https://doi.org/10.1124/dmd.115.068809
  6. de Wildt, Saskia N.

    1. You have access
      Human Intestinal PEPT1 Transporter Expression and Localization in Preterm and Term Infants
      Miriam G. Mooij, Barbara E. A. de Koning, Dicky J. Lindenbergh-Kortleve, Ytje Simons-Oosterhuis, Bianca D. van Groen, Dick Tibboel, Janneke N. Samsom and Saskia N. de Wildt
      Drug Metabolism and Disposition July 2016, 44 (7) 1014-1019; DOI: https://doi.org/10.1124/dmd.115.068809
    2. You have access
      Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life
      Miriam G. Mooij, Evita van de Steeg, Joost van Rosmalen, Jonathan D. Windster, Barbara A.E. de Koning, Wouter H. J. Vaes, Bianca D. van Groen, Dick Tibboel, Heleen M. Wortelboer and Saskia N. de Wildt
      Drug Metabolism and Disposition July 2016, 44 (7) 1005-1013; DOI: https://doi.org/10.1124/dmd.115.068577
  7. Dinh, Jean C.

    1. You have access
      Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children
      Jean C. Dinh, Robin E. Pearce, Leon Van Haandel, Andrea Gaedigk and J. Steven Leeder
      Drug Metabolism and Disposition July 2016, 44 (7) 1070-1079; DOI: https://doi.org/10.1124/dmd.116.069518
  8. Dolinoy, Dana C.

    1. You have access
      Correlation between Conjugated Bisphenol A Concentrations and Efflux Transporter Expression in Human Fetal Livers
      Jamie E. Moscovitz, Muna S. Nahar, Stuart L. Shalat, Angela L. Slitt, Dana C. Dolinoy and Lauren M. Aleksunes
      Drug Metabolism and Disposition July 2016, 44 (7) 1061-1065; DOI: https://doi.org/10.1124/dmd.115.068668
  9. Dorko, Kenneth

    1. You have access
      Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny
      Nicholas L. Giebel, Jeffrey D. Shadley, D. Gail McCarver, Kenneth Dorko, Roberto Gramignoli, Stephen C. Strom, Ke Yan, Pippa M. Simpson and Ronald N. Hines
      Drug Metabolism and Disposition July 2016, 44 (7) 1027-1037; DOI: https://doi.org/10.1124/dmd.116.069344

E

  1. Earp, Justin C.

    1. You have access
      Role of Quantitative Clinical Pharmacology in Pediatric Approval and Labeling
      Nitin Mehrotra, Atul Bhattaram, Justin C. Earp, Jeffry Florian, Kevin Krudys, Jee Eun Lee, Joo Yeon Lee, Jiang Liu, Yeruk Mulugeta, Jingyu Yu, Ping Zhao and Vikram Sinha
      Drug Metabolism and Disposition July 2016, 44 (7) 924-933; DOI: https://doi.org/10.1124/dmd.116.069559
  2. Edginton, Andrea N.

    1. You have access
      Examining Small Intestinal Transit Time as a Function of Age: Is There Evidence to Support Age-Dependent Differences among Children?
      Anil R. Maharaj and Andrea N. Edginton
      Drug Metabolism and Disposition July 2016, 44 (7) 1080-1089; DOI: https://doi.org/10.1124/dmd.115.068700
  3. Elbast, Walid

    1. You have access
      New Insights in Tissue Distribution, Metabolism, and Excretion of [3H]-Labeled Antibody Maytansinoid Conjugates in Female Tumor-Bearing Nude Rats
      Markus Walles, Bettina Rudolph, Thierry Wolf, Julien Bourgailh, Martina Suetterlin, Thomas Moenius, Gisela Peraus, Olivier Heudi, Walid Elbast, Christian Lanshoeft and Sanela Bilic
      Drug Metabolism and Disposition July 2016, 44 (7) 897-910; DOI: https://doi.org/10.1124/dmd.115.069021
  4. Elmorsi, Yasmine

    1. You have access
      Ontogeny of Hepatic Drug Transporters and Relevance to Drugs Used in Pediatrics
      Yasmine Elmorsi, Jill Barber and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition July 2016, 44 (7) 992-998; DOI: https://doi.org/10.1124/dmd.115.067801

F

  1. Fan, Jianghong

    1. You have access
      Metabolite Kinetics: The Segregated Flow Model for Intestinal and Whole Body Physiologically Based Pharmacokinetic Modeling to Describe Intestinal and Hepatic Glucuronidation of Morphine in Rats In Vivo
      Qi Joy Yang, Jianghong Fan, Shu Chen, Lutan Liu, Huadong Sun and K. Sandy Pang
      Drug Metabolism and Disposition July 2016, 44 (7) 1123-1138; DOI: https://doi.org/10.1124/dmd.116.069542
  2. Fattah, Sarinj

    1. You have access
      Effect of Age on The Hepatocellularity Number for Wistar rats
      Sarinj Fattah, Patrick Augustijns and Pieter Annaert
      Drug Metabolism and Disposition July 2016, 44 (7) 944-947; DOI: https://doi.org/10.1124/dmd.115.066381
  3. Florian, Jeffry

    1. You have access
      Role of Quantitative Clinical Pharmacology in Pediatric Approval and Labeling
      Nitin Mehrotra, Atul Bhattaram, Justin C. Earp, Jeffry Florian, Kevin Krudys, Jee Eun Lee, Joo Yeon Lee, Jiang Liu, Yeruk Mulugeta, Jingyu Yu, Ping Zhao and Vikram Sinha
      Drug Metabolism and Disposition July 2016, 44 (7) 924-933; DOI: https://doi.org/10.1124/dmd.116.069559
  4. Friesen, Craig

    1. Open Access
      Decreased Pregnane X Receptor Expression in Children with Active Crohn’s Disease
      Valentina Shakhnovich, Carrie Vyhlidal, Craig Friesen, Amber Hildreth, Vivekanand Singh, James Daniel, Gregory L. Kearns and J. Steven Leeder
      Drug Metabolism and Disposition July 2016, 44 (7) 1066-1069; DOI: https://doi.org/10.1124/dmd.115.068742

G

  1. Gaedigk, Andrea

    1. You have access
      Developmental Expression of CYP2B6: A Comprehensive Analysis of mRNA Expression, Protein Content and Bupropion Hydroxylase Activity and the Impact of Genetic Variation
      Robin E. Pearce, Roger Gaedigk, Greyson P. Twist, Hongying Dai, Amanda K. Riffel, J. Steven Leeder and Andrea Gaedigk
      Drug Metabolism and Disposition July 2016, 44 (7) 948-958; DOI: https://doi.org/10.1124/dmd.115.067546
    2. You have access
      Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children
      Jean C. Dinh, Robin E. Pearce, Leon Van Haandel, Andrea Gaedigk and J. Steven Leeder
      Drug Metabolism and Disposition July 2016, 44 (7) 1070-1079; DOI: https://doi.org/10.1124/dmd.116.069518
  2. Gaedigk, Roger

    1. You have access
      Developmental Expression of CYP2B6: A Comprehensive Analysis of mRNA Expression, Protein Content and Bupropion Hydroxylase Activity and the Impact of Genetic Variation
      Robin E. Pearce, Roger Gaedigk, Greyson P. Twist, Hongying Dai, Amanda K. Riffel, J. Steven Leeder and Andrea Gaedigk
      Drug Metabolism and Disposition July 2016, 44 (7) 948-958; DOI: https://doi.org/10.1124/dmd.115.067546
  3. Gajjar, Amar J.

    1. You have access
      Population Pharmacokinetics of Oral Topotecan in Infants and Very Young Children with Brain Tumors Demonstrates a Role of ABCG2 rs4148157 on the Absorption Rate Constant
      Jessica K. Roberts, Anna V. Birg, Tong Lin, Vinay M. Daryani, John C. Panetta, Alberto Broniscer, Giles W. Robinson, Amar J. Gajjar and Clinton F. Stewart
      Drug Metabolism and Disposition July 2016, 44 (7) 1116-1122; DOI: https://doi.org/10.1124/dmd.115.068676
  4. Giebel, Nicholas L.

    1. You have access
      Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny
      Nicholas L. Giebel, Jeffrey D. Shadley, D. Gail McCarver, Kenneth Dorko, Roberto Gramignoli, Stephen C. Strom, Ke Yan, Pippa M. Simpson and Ronald N. Hines
      Drug Metabolism and Disposition July 2016, 44 (7) 1027-1037; DOI: https://doi.org/10.1124/dmd.116.069344
  5. Gramignoli, Roberto

    1. You have access
      Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny
      Nicholas L. Giebel, Jeffrey D. Shadley, D. Gail McCarver, Kenneth Dorko, Roberto Gramignoli, Stephen C. Strom, Ke Yan, Pippa M. Simpson and Ronald N. Hines
      Drug Metabolism and Disposition July 2016, 44 (7) 1027-1037; DOI: https://doi.org/10.1124/dmd.116.069344

H

  1. Hao, Haiping

    1. Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      You have access
      Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      Meijuan Xu, Haiping Hao, Lifeng Jiang, Yidan Wei, Fang Zhou, Jianguo Sun, Jingwei Zhang, Hui Ji, Guangji Wang, Wenzheng Ju and Ping Li
      Drug Metabolism and Disposition July 2016, 44 (7) 878-887; DOI: https://doi.org/10.1124/dmd.116.069914
  2. Heudi, Olivier

    1. You have access
      New Insights in Tissue Distribution, Metabolism, and Excretion of [3H]-Labeled Antibody Maytansinoid Conjugates in Female Tumor-Bearing Nude Rats
      Markus Walles, Bettina Rudolph, Thierry Wolf, Julien Bourgailh, Martina Suetterlin, Thomas Moenius, Gisela Peraus, Olivier Heudi, Walid Elbast, Christian Lanshoeft and Sanela Bilic
      Drug Metabolism and Disposition July 2016, 44 (7) 897-910; DOI: https://doi.org/10.1124/dmd.115.069021
  3. Hildreth, Amber

    1. Open Access
      Decreased Pregnane X Receptor Expression in Children with Active Crohn’s Disease
      Valentina Shakhnovich, Carrie Vyhlidal, Craig Friesen, Amber Hildreth, Vivekanand Singh, James Daniel, Gregory L. Kearns and J. Steven Leeder
      Drug Metabolism and Disposition July 2016, 44 (7) 1066-1069; DOI: https://doi.org/10.1124/dmd.115.068742
  4. Hines, Ronald N.

    1. You have access
      Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny
      Ronald N. Hines, Pippa M. Simpson and D. Gail McCarver
      Drug Metabolism and Disposition July 2016, 44 (7) 959-966; DOI: https://doi.org/10.1124/dmd.115.068957
    2. You have access
      Expression Patterns of Organic Anion Transporting Polypeptides 1B1 and 1B3 Protein in Human Pediatric Liver
      Margaret M. S. Thomson, Ronald N. Hines, Erin G. Schuetz and Bernd Meibohm
      Drug Metabolism and Disposition July 2016, 44 (7) 999-1004; DOI: https://doi.org/10.1124/dmd.115.069252
    3. You have access
      Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny
      Nicholas L. Giebel, Jeffrey D. Shadley, D. Gail McCarver, Kenneth Dorko, Roberto Gramignoli, Stephen C. Strom, Ke Yan, Pippa M. Simpson and Ronald N. Hines
      Drug Metabolism and Disposition July 2016, 44 (7) 1027-1037; DOI: https://doi.org/10.1124/dmd.116.069344

I

  1. Inoue, Takashi

    1. Individual Differences in Metabolic Clearance of <em>S</em>-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers
      You have access
      Individual Differences in Metabolic Clearance of S-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Mirai Kawano, Makiko Shimizu, Akiko Toda, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2016, 44 (7) 911-915; DOI: https://doi.org/10.1124/dmd.116.070383
  2. Iwamura, Atsushi

    1. You have access
      Zomepirac Acyl Glucuronide Is Responsible for Zomepirac-Induced Acute Kidney Injury in Mice
      Atsushi Iwamura, Katsuhito Watanabe, Sho Akai, Tsubasa Nishinosono, Koichi Tsuneyama, Shingo Oda, Toshiyuki Kume and Tsuyoshi Yokoi
      Drug Metabolism and Disposition July 2016, 44 (7) 888-896; DOI: https://doi.org/10.1124/dmd.116.069575

J

  1. Jamei, Masoud

    1. You have access
      How Does In Vivo Biliary Elimination of Drugs Change with Age? Evidence from In Vitro and Clinical Data Using a Systems Pharmacology Approach
      Trevor N. Johnson, Masoud Jamei and Karen Rowland-Yeo
      Drug Metabolism and Disposition July 2016, 44 (7) 1090-1098; DOI: https://doi.org/10.1124/dmd.115.068643
  2. Ji, Hui

    1. Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      You have access
      Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      Meijuan Xu, Haiping Hao, Lifeng Jiang, Yidan Wei, Fang Zhou, Jianguo Sun, Jingwei Zhang, Hui Ji, Guangji Wang, Wenzheng Ju and Ping Li
      Drug Metabolism and Disposition July 2016, 44 (7) 878-887; DOI: https://doi.org/10.1124/dmd.116.069914
  3. Jiang, Lifeng

    1. Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      You have access
      Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      Meijuan Xu, Haiping Hao, Lifeng Jiang, Yidan Wei, Fang Zhou, Jianguo Sun, Jingwei Zhang, Hui Ji, Guangji Wang, Wenzheng Ju and Ping Li
      Drug Metabolism and Disposition July 2016, 44 (7) 878-887; DOI: https://doi.org/10.1124/dmd.116.069914
  4. Johnson, Trevor N.

    1. You have access
      How Does In Vivo Biliary Elimination of Drugs Change with Age? Evidence from In Vitro and Clinical Data Using a Systems Pharmacology Approach
      Trevor N. Johnson, Masoud Jamei and Karen Rowland-Yeo
      Drug Metabolism and Disposition July 2016, 44 (7) 1090-1098; DOI: https://doi.org/10.1124/dmd.115.068643
  5. Ju, Wenzheng

    1. Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      You have access
      Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      Meijuan Xu, Haiping Hao, Lifeng Jiang, Yidan Wei, Fang Zhou, Jianguo Sun, Jingwei Zhang, Hui Ji, Guangji Wang, Wenzheng Ju and Ping Li
      Drug Metabolism and Disposition July 2016, 44 (7) 878-887; DOI: https://doi.org/10.1124/dmd.116.069914

K

  1. Kamiyama, Yoshiteru

    1. You have access
      Considering Age Variation When Coining Drugs as High versus Low Hepatic Extraction Ratio
      Farzaneh Salem, Khaled Abduljalil, Yoshiteru Kamiyama and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition July 2016, 44 (7) 1099-1102; DOI: https://doi.org/10.1124/dmd.115.067595
  2. Kawano, Mirai

    1. Individual Differences in Metabolic Clearance of <em>S</em>-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers
      You have access
      Individual Differences in Metabolic Clearance of S-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Mirai Kawano, Makiko Shimizu, Akiko Toda, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2016, 44 (7) 911-915; DOI: https://doi.org/10.1124/dmd.116.070383
  3. Kearns, Gregory L.

    1. Open Access
      Decreased Pregnane X Receptor Expression in Children with Active Crohn’s Disease
      Valentina Shakhnovich, Carrie Vyhlidal, Craig Friesen, Amber Hildreth, Vivekanand Singh, James Daniel, Gregory L. Kearns and J. Steven Leeder
      Drug Metabolism and Disposition July 2016, 44 (7) 1066-1069; DOI: https://doi.org/10.1124/dmd.115.068742
  4. Khalil, Feras

    1. You have access
      Predicting Stereoselective Disposition of Carvedilol in Adult and Pediatric Chronic Heart Failure Patients by Incorporating Pathophysiological Changes in Organ Blood Flows–A Physiologically Based Pharmacokinetic Approach
      Muhammad Fawad Rasool, Feras Khalil and Stephanie Läer
      Drug Metabolism and Disposition July 2016, 44 (7) 1103-1115; DOI: https://doi.org/10.1124/dmd.115.068858
  5. Klaassen, Curtis D.

    1. You have access
      Age-Specific Regulation of Drug-Processing Genes in Mouse Liver by Ligands of Xenobiotic-Sensing Transcription Factors
      Cindy Yanfei Li, Helen J. Renaud, Curtis D. Klaassen and Julia Yue Cui
      Drug Metabolism and Disposition July 2016, 44 (7) 1038-1049; DOI: https://doi.org/10.1124/dmd.115.066639
  6. Krudys, Kevin

    1. You have access
      Role of Quantitative Clinical Pharmacology in Pediatric Approval and Labeling
      Nitin Mehrotra, Atul Bhattaram, Justin C. Earp, Jeffry Florian, Kevin Krudys, Jee Eun Lee, Joo Yeon Lee, Jiang Liu, Yeruk Mulugeta, Jingyu Yu, Ping Zhao and Vikram Sinha
      Drug Metabolism and Disposition July 2016, 44 (7) 924-933; DOI: https://doi.org/10.1124/dmd.116.069559
  7. Kume, Toshiyuki

    1. You have access
      Zomepirac Acyl Glucuronide Is Responsible for Zomepirac-Induced Acute Kidney Injury in Mice
      Atsushi Iwamura, Katsuhito Watanabe, Sho Akai, Tsubasa Nishinosono, Koichi Tsuneyama, Shingo Oda, Toshiyuki Kume and Tsuyoshi Yokoi
      Drug Metabolism and Disposition July 2016, 44 (7) 888-896; DOI: https://doi.org/10.1124/dmd.116.069575

L

  1. Läer, Stephanie

    1. You have access
      Predicting Stereoselective Disposition of Carvedilol in Adult and Pediatric Chronic Heart Failure Patients by Incorporating Pathophysiological Changes in Organ Blood Flows–A Physiologically Based Pharmacokinetic Approach
      Muhammad Fawad Rasool, Feras Khalil and Stephanie Läer
      Drug Metabolism and Disposition July 2016, 44 (7) 1103-1115; DOI: https://doi.org/10.1124/dmd.115.068858
  2. Lanshoeft, Christian

    1. You have access
      New Insights in Tissue Distribution, Metabolism, and Excretion of [3H]-Labeled Antibody Maytansinoid Conjugates in Female Tumor-Bearing Nude Rats
      Markus Walles, Bettina Rudolph, Thierry Wolf, Julien Bourgailh, Martina Suetterlin, Thomas Moenius, Gisela Peraus, Olivier Heudi, Walid Elbast, Christian Lanshoeft and Sanela Bilic
      Drug Metabolism and Disposition July 2016, 44 (7) 897-910; DOI: https://doi.org/10.1124/dmd.115.069021
  3. Lee, Jee Eun

    1. You have access
      Role of Quantitative Clinical Pharmacology in Pediatric Approval and Labeling
      Nitin Mehrotra, Atul Bhattaram, Justin C. Earp, Jeffry Florian, Kevin Krudys, Jee Eun Lee, Joo Yeon Lee, Jiang Liu, Yeruk Mulugeta, Jingyu Yu, Ping Zhao and Vikram Sinha
      Drug Metabolism and Disposition July 2016, 44 (7) 924-933; DOI: https://doi.org/10.1124/dmd.116.069559
  4. Lee, Joo Yeon

    1. You have access
      Role of Quantitative Clinical Pharmacology in Pediatric Approval and Labeling
      Nitin Mehrotra, Atul Bhattaram, Justin C. Earp, Jeffry Florian, Kevin Krudys, Jee Eun Lee, Joo Yeon Lee, Jiang Liu, Yeruk Mulugeta, Jingyu Yu, Ping Zhao and Vikram Sinha
      Drug Metabolism and Disposition July 2016, 44 (7) 924-933; DOI: https://doi.org/10.1124/dmd.116.069559
  5. Leeder, J. Steven

    1. You have access
      Developmental Expression of CYP2B6: A Comprehensive Analysis of mRNA Expression, Protein Content and Bupropion Hydroxylase Activity and the Impact of Genetic Variation
      Robin E. Pearce, Roger Gaedigk, Greyson P. Twist, Hongying Dai, Amanda K. Riffel, J. Steven Leeder and Andrea Gaedigk
      Drug Metabolism and Disposition July 2016, 44 (7) 948-958; DOI: https://doi.org/10.1124/dmd.115.067546
    2. You have access
      Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children
      Jean C. Dinh, Robin E. Pearce, Leon Van Haandel, Andrea Gaedigk and J. Steven Leeder
      Drug Metabolism and Disposition July 2016, 44 (7) 1070-1079; DOI: https://doi.org/10.1124/dmd.116.069518
    3. You have access
      Dynamics of Cytosine Methylation in the Proximal Promoters of CYP3A4 and CYP3A7 in Pediatric and Prenatal Livers
      Carrie A. Vyhlidal, Chengpeng Bi, Shui Qing Ye and J. Steven Leeder
      Drug Metabolism and Disposition July 2016, 44 (7) 1020-1026; DOI: https://doi.org/10.1124/dmd.115.068726
    4. You have access
      Challenges and Opportunities for Increasing the Knowledge Base Related to Drug Biotransformation and Pharmacokinetics during Growth and Development
      J. Steven Leeder and Bernd Meibohm
      Drug Metabolism and Disposition July 2016, 44 (7) 916-923; DOI: https://doi.org/10.1124/dmd.116.071159
    5. Open Access
      Decreased Pregnane X Receptor Expression in Children with Active Crohn’s Disease
      Valentina Shakhnovich, Carrie Vyhlidal, Craig Friesen, Amber Hildreth, Vivekanand Singh, James Daniel, Gregory L. Kearns and J. Steven Leeder
      Drug Metabolism and Disposition July 2016, 44 (7) 1066-1069; DOI: https://doi.org/10.1124/dmd.115.068742
  6. Li, Cindy Yanfei

    1. You have access
      Age-Specific Regulation of Drug-Processing Genes in Mouse Liver by Ligands of Xenobiotic-Sensing Transcription Factors
      Cindy Yanfei Li, Helen J. Renaud, Curtis D. Klaassen and Julia Yue Cui
      Drug Metabolism and Disposition July 2016, 44 (7) 1038-1049; DOI: https://doi.org/10.1124/dmd.115.066639
  7. Li, Ping

    1. Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      You have access
      Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      Meijuan Xu, Haiping Hao, Lifeng Jiang, Yidan Wei, Fang Zhou, Jianguo Sun, Jingwei Zhang, Hui Ji, Guangji Wang, Wenzheng Ju and Ping Li
      Drug Metabolism and Disposition July 2016, 44 (7) 878-887; DOI: https://doi.org/10.1124/dmd.116.069914
  8. Lin, Tong

    1. You have access
      Population Pharmacokinetics of Oral Topotecan in Infants and Very Young Children with Brain Tumors Demonstrates a Role of ABCG2 rs4148157 on the Absorption Rate Constant
      Jessica K. Roberts, Anna V. Birg, Tong Lin, Vinay M. Daryani, John C. Panetta, Alberto Broniscer, Giles W. Robinson, Amar J. Gajjar and Clinton F. Stewart
      Drug Metabolism and Disposition July 2016, 44 (7) 1116-1122; DOI: https://doi.org/10.1124/dmd.115.068676
  9. Lindenbergh-Kortleve, Dicky J.

    1. You have access
      Human Intestinal PEPT1 Transporter Expression and Localization in Preterm and Term Infants
      Miriam G. Mooij, Barbara E. A. de Koning, Dicky J. Lindenbergh-Kortleve, Ytje Simons-Oosterhuis, Bianca D. van Groen, Dick Tibboel, Janneke N. Samsom and Saskia N. de Wildt
      Drug Metabolism and Disposition July 2016, 44 (7) 1014-1019; DOI: https://doi.org/10.1124/dmd.115.068809
  10. Liu, Jiang

    1. You have access
      Role of Quantitative Clinical Pharmacology in Pediatric Approval and Labeling
      Nitin Mehrotra, Atul Bhattaram, Justin C. Earp, Jeffry Florian, Kevin Krudys, Jee Eun Lee, Joo Yeon Lee, Jiang Liu, Yeruk Mulugeta, Jingyu Yu, Ping Zhao and Vikram Sinha
      Drug Metabolism and Disposition July 2016, 44 (7) 924-933; DOI: https://doi.org/10.1124/dmd.116.069559
  11. Liu, Lutan

    1. You have access
      Metabolite Kinetics: The Segregated Flow Model for Intestinal and Whole Body Physiologically Based Pharmacokinetic Modeling to Describe Intestinal and Hepatic Glucuronidation of Morphine in Rats In Vivo
      Qi Joy Yang, Jianghong Fan, Shu Chen, Lutan Liu, Huadong Sun and K. Sandy Pang
      Drug Metabolism and Disposition July 2016, 44 (7) 1123-1138; DOI: https://doi.org/10.1124/dmd.116.069542

M

  1. Maharaj, Anil R.

    1. You have access
      Examining Small Intestinal Transit Time as a Function of Age: Is There Evidence to Support Age-Dependent Differences among Children?
      Anil R. Maharaj and Andrea N. Edginton
      Drug Metabolism and Disposition July 2016, 44 (7) 1080-1089; DOI: https://doi.org/10.1124/dmd.115.068700
  2. Martovetsky, Gleb

    1. You have access
      Kidney versus Liver Specification of SLC and ABC Drug Transporters, Tight Junction Molecules, and Biomarkers
      Gleb Martovetsky, Kevin T. Bush and Sanjay K. Nigam
      Drug Metabolism and Disposition July 2016, 44 (7) 1050-1060; DOI: https://doi.org/10.1124/dmd.115.068254
  3. McCarver, D. Gail

    1. You have access
      Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny
      Ronald N. Hines, Pippa M. Simpson and D. Gail McCarver
      Drug Metabolism and Disposition July 2016, 44 (7) 959-966; DOI: https://doi.org/10.1124/dmd.115.068957
    2. You have access
      Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny
      Nicholas L. Giebel, Jeffrey D. Shadley, D. Gail McCarver, Kenneth Dorko, Roberto Gramignoli, Stephen C. Strom, Ke Yan, Pippa M. Simpson and Ronald N. Hines
      Drug Metabolism and Disposition July 2016, 44 (7) 1027-1037; DOI: https://doi.org/10.1124/dmd.116.069344
  4. Mehrotra, Nitin

    1. You have access
      Role of Quantitative Clinical Pharmacology in Pediatric Approval and Labeling
      Nitin Mehrotra, Atul Bhattaram, Justin C. Earp, Jeffry Florian, Kevin Krudys, Jee Eun Lee, Joo Yeon Lee, Jiang Liu, Yeruk Mulugeta, Jingyu Yu, Ping Zhao and Vikram Sinha
      Drug Metabolism and Disposition July 2016, 44 (7) 924-933; DOI: https://doi.org/10.1124/dmd.116.069559
  5. Meibohm, Bernd

    1. You have access
      Expression Patterns of Organic Anion Transporting Polypeptides 1B1 and 1B3 Protein in Human Pediatric Liver
      Margaret M. S. Thomson, Ronald N. Hines, Erin G. Schuetz and Bernd Meibohm
      Drug Metabolism and Disposition July 2016, 44 (7) 999-1004; DOI: https://doi.org/10.1124/dmd.115.069252
    2. You have access
      Challenges and Opportunities for Increasing the Knowledge Base Related to Drug Biotransformation and Pharmacokinetics during Growth and Development
      J. Steven Leeder and Bernd Meibohm
      Drug Metabolism and Disposition July 2016, 44 (7) 916-923; DOI: https://doi.org/10.1124/dmd.116.071159
  6. Moenius, Thomas

    1. You have access
      New Insights in Tissue Distribution, Metabolism, and Excretion of [3H]-Labeled Antibody Maytansinoid Conjugates in Female Tumor-Bearing Nude Rats
      Markus Walles, Bettina Rudolph, Thierry Wolf, Julien Bourgailh, Martina Suetterlin, Thomas Moenius, Gisela Peraus, Olivier Heudi, Walid Elbast, Christian Lanshoeft and Sanela Bilic
      Drug Metabolism and Disposition July 2016, 44 (7) 897-910; DOI: https://doi.org/10.1124/dmd.115.069021
  7. Mooij, Miriam G.

    1. You have access
      Human Intestinal PEPT1 Transporter Expression and Localization in Preterm and Term Infants
      Miriam G. Mooij, Barbara E. A. de Koning, Dicky J. Lindenbergh-Kortleve, Ytje Simons-Oosterhuis, Bianca D. van Groen, Dick Tibboel, Janneke N. Samsom and Saskia N. de Wildt
      Drug Metabolism and Disposition July 2016, 44 (7) 1014-1019; DOI: https://doi.org/10.1124/dmd.115.068809
    2. You have access
      Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life
      Miriam G. Mooij, Evita van de Steeg, Joost van Rosmalen, Jonathan D. Windster, Barbara A.E. de Koning, Wouter H. J. Vaes, Bianca D. van Groen, Dick Tibboel, Heleen M. Wortelboer and Saskia N. de Wildt
      Drug Metabolism and Disposition July 2016, 44 (7) 1005-1013; DOI: https://doi.org/10.1124/dmd.115.068577
  8. Moscovitz, Jamie E.

    1. You have access
      Correlation between Conjugated Bisphenol A Concentrations and Efflux Transporter Expression in Human Fetal Livers
      Jamie E. Moscovitz, Muna S. Nahar, Stuart L. Shalat, Angela L. Slitt, Dana C. Dolinoy and Lauren M. Aleksunes
      Drug Metabolism and Disposition July 2016, 44 (7) 1061-1065; DOI: https://doi.org/10.1124/dmd.115.068668
  9. Mulugeta, Yeruk

    1. You have access
      Role of Quantitative Clinical Pharmacology in Pediatric Approval and Labeling
      Nitin Mehrotra, Atul Bhattaram, Justin C. Earp, Jeffry Florian, Kevin Krudys, Jee Eun Lee, Joo Yeon Lee, Jiang Liu, Yeruk Mulugeta, Jingyu Yu, Ping Zhao and Vikram Sinha
      Drug Metabolism and Disposition July 2016, 44 (7) 924-933; DOI: https://doi.org/10.1124/dmd.116.069559

N

  1. Nahar, Muna S.

    1. You have access
      Correlation between Conjugated Bisphenol A Concentrations and Efflux Transporter Expression in Human Fetal Livers
      Jamie E. Moscovitz, Muna S. Nahar, Stuart L. Shalat, Angela L. Slitt, Dana C. Dolinoy and Lauren M. Aleksunes
      Drug Metabolism and Disposition July 2016, 44 (7) 1061-1065; DOI: https://doi.org/10.1124/dmd.115.068668
  2. Nandhikonda, Premchendar

    1. Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development
      You have access
      Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development
      Natalie C. Sadler, Premchendar Nandhikonda, Bobbie-Jo Webb-Robertson, Charles Ansong, Lindsey N. Anderson, Jordan N. Smith, Richard A. Corley and Aaron T. Wright
      Drug Metabolism and Disposition July 2016, 44 (7) 984-991; DOI: https://doi.org/10.1124/dmd.115.068593
  3. Nigam, Sanjay K.

    1. You have access
      Kidney versus Liver Specification of SLC and ABC Drug Transporters, Tight Junction Molecules, and Biomarkers
      Gleb Martovetsky, Kevin T. Bush and Sanjay K. Nigam
      Drug Metabolism and Disposition July 2016, 44 (7) 1050-1060; DOI: https://doi.org/10.1124/dmd.115.068254
  4. Nishinosono, Tsubasa

    1. You have access
      Zomepirac Acyl Glucuronide Is Responsible for Zomepirac-Induced Acute Kidney Injury in Mice
      Atsushi Iwamura, Katsuhito Watanabe, Sho Akai, Tsubasa Nishinosono, Koichi Tsuneyama, Shingo Oda, Toshiyuki Kume and Tsuyoshi Yokoi
      Drug Metabolism and Disposition July 2016, 44 (7) 888-896; DOI: https://doi.org/10.1124/dmd.116.069575

O

  1. Oda, Shingo

    1. You have access
      Zomepirac Acyl Glucuronide Is Responsible for Zomepirac-Induced Acute Kidney Injury in Mice
      Atsushi Iwamura, Katsuhito Watanabe, Sho Akai, Tsubasa Nishinosono, Koichi Tsuneyama, Shingo Oda, Toshiyuki Kume and Tsuyoshi Yokoi
      Drug Metabolism and Disposition July 2016, 44 (7) 888-896; DOI: https://doi.org/10.1124/dmd.116.069575

P

  1. Panetta, John C.

    1. You have access
      Population Pharmacokinetics of Oral Topotecan in Infants and Very Young Children with Brain Tumors Demonstrates a Role of ABCG2 rs4148157 on the Absorption Rate Constant
      Jessica K. Roberts, Anna V. Birg, Tong Lin, Vinay M. Daryani, John C. Panetta, Alberto Broniscer, Giles W. Robinson, Amar J. Gajjar and Clinton F. Stewart
      Drug Metabolism and Disposition July 2016, 44 (7) 1116-1122; DOI: https://doi.org/10.1124/dmd.115.068676
  2. Pang, K. Sandy

    1. You have access
      Metabolite Kinetics: The Segregated Flow Model for Intestinal and Whole Body Physiologically Based Pharmacokinetic Modeling to Describe Intestinal and Hepatic Glucuronidation of Morphine in Rats In Vivo
      Qi Joy Yang, Jianghong Fan, Shu Chen, Lutan Liu, Huadong Sun and K. Sandy Pang
      Drug Metabolism and Disposition July 2016, 44 (7) 1123-1138; DOI: https://doi.org/10.1124/dmd.116.069542
  3. Pearce, Robin E.

    1. You have access
      Developmental Expression of CYP2B6: A Comprehensive Analysis of mRNA Expression, Protein Content and Bupropion Hydroxylase Activity and the Impact of Genetic Variation
      Robin E. Pearce, Roger Gaedigk, Greyson P. Twist, Hongying Dai, Amanda K. Riffel, J. Steven Leeder and Andrea Gaedigk
      Drug Metabolism and Disposition July 2016, 44 (7) 948-958; DOI: https://doi.org/10.1124/dmd.115.067546
    2. You have access
      Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children
      Jean C. Dinh, Robin E. Pearce, Leon Van Haandel, Andrea Gaedigk and J. Steven Leeder
      Drug Metabolism and Disposition July 2016, 44 (7) 1070-1079; DOI: https://doi.org/10.1124/dmd.116.069518
  4. Peraus, Gisela

    1. You have access
      New Insights in Tissue Distribution, Metabolism, and Excretion of [3H]-Labeled Antibody Maytansinoid Conjugates in Female Tumor-Bearing Nude Rats
      Markus Walles, Bettina Rudolph, Thierry Wolf, Julien Bourgailh, Martina Suetterlin, Thomas Moenius, Gisela Peraus, Olivier Heudi, Walid Elbast, Christian Lanshoeft and Sanela Bilic
      Drug Metabolism and Disposition July 2016, 44 (7) 897-910; DOI: https://doi.org/10.1124/dmd.115.069021

R

  1. Rasool, Muhammad Fawad

    1. You have access
      Predicting Stereoselective Disposition of Carvedilol in Adult and Pediatric Chronic Heart Failure Patients by Incorporating Pathophysiological Changes in Organ Blood Flows–A Physiologically Based Pharmacokinetic Approach
      Muhammad Fawad Rasool, Feras Khalil and Stephanie Läer
      Drug Metabolism and Disposition July 2016, 44 (7) 1103-1115; DOI: https://doi.org/10.1124/dmd.115.068858
  2. Renaud, Helen J.

    1. You have access
      Age-Specific Regulation of Drug-Processing Genes in Mouse Liver by Ligands of Xenobiotic-Sensing Transcription Factors
      Cindy Yanfei Li, Helen J. Renaud, Curtis D. Klaassen and Julia Yue Cui
      Drug Metabolism and Disposition July 2016, 44 (7) 1038-1049; DOI: https://doi.org/10.1124/dmd.115.066639
  3. Riches, Zoe

    1. You have access
      The Ontogeny and Population Variability of Human Hepatic NADPH Dehydrogenase Quinone Oxido-Reductase 1 (NQO1)
      Luc R.A. Rougée, Zoe Riches, Jacob M. Berman and Abby C. Collier
      Drug Metabolism and Disposition July 2016, 44 (7) 967-974; DOI: https://doi.org/10.1124/dmd.115.068650
  4. Riffel, Amanda K.

    1. You have access
      Developmental Expression of CYP2B6: A Comprehensive Analysis of mRNA Expression, Protein Content and Bupropion Hydroxylase Activity and the Impact of Genetic Variation
      Robin E. Pearce, Roger Gaedigk, Greyson P. Twist, Hongying Dai, Amanda K. Riffel, J. Steven Leeder and Andrea Gaedigk
      Drug Metabolism and Disposition July 2016, 44 (7) 948-958; DOI: https://doi.org/10.1124/dmd.115.067546
  5. Rioux, Nathalie

    1. You have access
      Physiologically Based Pharmacokinetic Modeling in Pediatric Oncology Drug Development
      Nathalie Rioux and Nigel J. Waters
      Drug Metabolism and Disposition July 2016, 44 (7) 934-943; DOI: https://doi.org/10.1124/dmd.115.068031
  6. Roberts, Jessica K.

    1. You have access
      Population Pharmacokinetics of Oral Topotecan in Infants and Very Young Children with Brain Tumors Demonstrates a Role of ABCG2 rs4148157 on the Absorption Rate Constant
      Jessica K. Roberts, Anna V. Birg, Tong Lin, Vinay M. Daryani, John C. Panetta, Alberto Broniscer, Giles W. Robinson, Amar J. Gajjar and Clinton F. Stewart
      Drug Metabolism and Disposition July 2016, 44 (7) 1116-1122; DOI: https://doi.org/10.1124/dmd.115.068676
  7. Robinson, Giles W.

    1. You have access
      Population Pharmacokinetics of Oral Topotecan in Infants and Very Young Children with Brain Tumors Demonstrates a Role of ABCG2 rs4148157 on the Absorption Rate Constant
      Jessica K. Roberts, Anna V. Birg, Tong Lin, Vinay M. Daryani, John C. Panetta, Alberto Broniscer, Giles W. Robinson, Amar J. Gajjar and Clinton F. Stewart
      Drug Metabolism and Disposition July 2016, 44 (7) 1116-1122; DOI: https://doi.org/10.1124/dmd.115.068676
  8. Rostami-Hodjegan, Amin

    1. You have access
      Ontogeny of Hepatic Drug Transporters and Relevance to Drugs Used in Pediatrics
      Yasmine Elmorsi, Jill Barber and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition July 2016, 44 (7) 992-998; DOI: https://doi.org/10.1124/dmd.115.067801
    2. You have access
      Considering Age Variation When Coining Drugs as High versus Low Hepatic Extraction Ratio
      Farzaneh Salem, Khaled Abduljalil, Yoshiteru Kamiyama and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition July 2016, 44 (7) 1099-1102; DOI: https://doi.org/10.1124/dmd.115.067595
  9. Rougée, Luc R.A.

    1. You have access
      The Ontogeny and Population Variability of Human Hepatic NADPH Dehydrogenase Quinone Oxido-Reductase 1 (NQO1)
      Luc R.A. Rougée, Zoe Riches, Jacob M. Berman and Abby C. Collier
      Drug Metabolism and Disposition July 2016, 44 (7) 967-974; DOI: https://doi.org/10.1124/dmd.115.068650
  10. Rowland-Yeo, Karen

    1. You have access
      How Does In Vivo Biliary Elimination of Drugs Change with Age? Evidence from In Vitro and Clinical Data Using a Systems Pharmacology Approach
      Trevor N. Johnson, Masoud Jamei and Karen Rowland-Yeo
      Drug Metabolism and Disposition July 2016, 44 (7) 1090-1098; DOI: https://doi.org/10.1124/dmd.115.068643
  11. Rudolph, Bettina

    1. You have access
      New Insights in Tissue Distribution, Metabolism, and Excretion of [3H]-Labeled Antibody Maytansinoid Conjugates in Female Tumor-Bearing Nude Rats
      Markus Walles, Bettina Rudolph, Thierry Wolf, Julien Bourgailh, Martina Suetterlin, Thomas Moenius, Gisela Peraus, Olivier Heudi, Walid Elbast, Christian Lanshoeft and Sanela Bilic
      Drug Metabolism and Disposition July 2016, 44 (7) 897-910; DOI: https://doi.org/10.1124/dmd.115.069021

S

  1. Sadler, Natalie C.

    1. Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development
      You have access
      Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development
      Natalie C. Sadler, Premchendar Nandhikonda, Bobbie-Jo Webb-Robertson, Charles Ansong, Lindsey N. Anderson, Jordan N. Smith, Richard A. Corley and Aaron T. Wright
      Drug Metabolism and Disposition July 2016, 44 (7) 984-991; DOI: https://doi.org/10.1124/dmd.115.068593
  2. Salem, Farzaneh

    1. You have access
      Considering Age Variation When Coining Drugs as High versus Low Hepatic Extraction Ratio
      Farzaneh Salem, Khaled Abduljalil, Yoshiteru Kamiyama and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition July 2016, 44 (7) 1099-1102; DOI: https://doi.org/10.1124/dmd.115.067595
  3. Samsom, Janneke N.

    1. You have access
      Human Intestinal PEPT1 Transporter Expression and Localization in Preterm and Term Infants
      Miriam G. Mooij, Barbara E. A. de Koning, Dicky J. Lindenbergh-Kortleve, Ytje Simons-Oosterhuis, Bianca D. van Groen, Dick Tibboel, Janneke N. Samsom and Saskia N. de Wildt
      Drug Metabolism and Disposition July 2016, 44 (7) 1014-1019; DOI: https://doi.org/10.1124/dmd.115.068809
  4. Sasaki, Erika

    1. Individual Differences in Metabolic Clearance of <em>S</em>-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers
      You have access
      Individual Differences in Metabolic Clearance of S-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Mirai Kawano, Makiko Shimizu, Akiko Toda, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2016, 44 (7) 911-915; DOI: https://doi.org/10.1124/dmd.116.070383
  5. Schuetz, Erin G.

    1. You have access
      Expression Patterns of Organic Anion Transporting Polypeptides 1B1 and 1B3 Protein in Human Pediatric Liver
      Margaret M. S. Thomson, Ronald N. Hines, Erin G. Schuetz and Bernd Meibohm
      Drug Metabolism and Disposition July 2016, 44 (7) 999-1004; DOI: https://doi.org/10.1124/dmd.115.069252
  6. Shadley, Jeffrey D.

    1. You have access
      Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny
      Nicholas L. Giebel, Jeffrey D. Shadley, D. Gail McCarver, Kenneth Dorko, Roberto Gramignoli, Stephen C. Strom, Ke Yan, Pippa M. Simpson and Ronald N. Hines
      Drug Metabolism and Disposition July 2016, 44 (7) 1027-1037; DOI: https://doi.org/10.1124/dmd.116.069344
  7. Shakhnovich, Valentina

    1. Open Access
      Decreased Pregnane X Receptor Expression in Children with Active Crohn’s Disease
      Valentina Shakhnovich, Carrie Vyhlidal, Craig Friesen, Amber Hildreth, Vivekanand Singh, James Daniel, Gregory L. Kearns and J. Steven Leeder
      Drug Metabolism and Disposition July 2016, 44 (7) 1066-1069; DOI: https://doi.org/10.1124/dmd.115.068742
  8. Shalat, Stuart L.

    1. You have access
      Correlation between Conjugated Bisphenol A Concentrations and Efflux Transporter Expression in Human Fetal Livers
      Jamie E. Moscovitz, Muna S. Nahar, Stuart L. Shalat, Angela L. Slitt, Dana C. Dolinoy and Lauren M. Aleksunes
      Drug Metabolism and Disposition July 2016, 44 (7) 1061-1065; DOI: https://doi.org/10.1124/dmd.115.068668
  9. Shimizu, Makiko

    1. Individual Differences in Metabolic Clearance of <em>S</em>-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers
      You have access
      Individual Differences in Metabolic Clearance of S-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Mirai Kawano, Makiko Shimizu, Akiko Toda, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2016, 44 (7) 911-915; DOI: https://doi.org/10.1124/dmd.116.070383
  10. Simons-Oosterhuis, Ytje

    1. You have access
      Human Intestinal PEPT1 Transporter Expression and Localization in Preterm and Term Infants
      Miriam G. Mooij, Barbara E. A. de Koning, Dicky J. Lindenbergh-Kortleve, Ytje Simons-Oosterhuis, Bianca D. van Groen, Dick Tibboel, Janneke N. Samsom and Saskia N. de Wildt
      Drug Metabolism and Disposition July 2016, 44 (7) 1014-1019; DOI: https://doi.org/10.1124/dmd.115.068809
  11. Simpson, Pippa M.

    1. You have access
      Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny
      Ronald N. Hines, Pippa M. Simpson and D. Gail McCarver
      Drug Metabolism and Disposition July 2016, 44 (7) 959-966; DOI: https://doi.org/10.1124/dmd.115.068957
    2. You have access
      Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny
      Nicholas L. Giebel, Jeffrey D. Shadley, D. Gail McCarver, Kenneth Dorko, Roberto Gramignoli, Stephen C. Strom, Ke Yan, Pippa M. Simpson and Ronald N. Hines
      Drug Metabolism and Disposition July 2016, 44 (7) 1027-1037; DOI: https://doi.org/10.1124/dmd.116.069344
  12. Singh, Vivekanand

    1. Open Access
      Decreased Pregnane X Receptor Expression in Children with Active Crohn’s Disease
      Valentina Shakhnovich, Carrie Vyhlidal, Craig Friesen, Amber Hildreth, Vivekanand Singh, James Daniel, Gregory L. Kearns and J. Steven Leeder
      Drug Metabolism and Disposition July 2016, 44 (7) 1066-1069; DOI: https://doi.org/10.1124/dmd.115.068742
  13. Sinha, Vikram

    1. You have access
      Role of Quantitative Clinical Pharmacology in Pediatric Approval and Labeling
      Nitin Mehrotra, Atul Bhattaram, Justin C. Earp, Jeffry Florian, Kevin Krudys, Jee Eun Lee, Joo Yeon Lee, Jiang Liu, Yeruk Mulugeta, Jingyu Yu, Ping Zhao and Vikram Sinha
      Drug Metabolism and Disposition July 2016, 44 (7) 924-933; DOI: https://doi.org/10.1124/dmd.116.069559
  14. Slitt, Angela L.

    1. You have access
      Correlation between Conjugated Bisphenol A Concentrations and Efflux Transporter Expression in Human Fetal Livers
      Jamie E. Moscovitz, Muna S. Nahar, Stuart L. Shalat, Angela L. Slitt, Dana C. Dolinoy and Lauren M. Aleksunes
      Drug Metabolism and Disposition July 2016, 44 (7) 1061-1065; DOI: https://doi.org/10.1124/dmd.115.068668
  15. Smith, Jordan N.

    1. Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development
      You have access
      Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development
      Natalie C. Sadler, Premchendar Nandhikonda, Bobbie-Jo Webb-Robertson, Charles Ansong, Lindsey N. Anderson, Jordan N. Smith, Richard A. Corley and Aaron T. Wright
      Drug Metabolism and Disposition July 2016, 44 (7) 984-991; DOI: https://doi.org/10.1124/dmd.115.068593
  16. Stewart, Clinton F.

    1. You have access
      Population Pharmacokinetics of Oral Topotecan in Infants and Very Young Children with Brain Tumors Demonstrates a Role of ABCG2 rs4148157 on the Absorption Rate Constant
      Jessica K. Roberts, Anna V. Birg, Tong Lin, Vinay M. Daryani, John C. Panetta, Alberto Broniscer, Giles W. Robinson, Amar J. Gajjar and Clinton F. Stewart
      Drug Metabolism and Disposition July 2016, 44 (7) 1116-1122; DOI: https://doi.org/10.1124/dmd.115.068676
  17. Strom, Stephen C.

    1. You have access
      Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny
      Nicholas L. Giebel, Jeffrey D. Shadley, D. Gail McCarver, Kenneth Dorko, Roberto Gramignoli, Stephen C. Strom, Ke Yan, Pippa M. Simpson and Ronald N. Hines
      Drug Metabolism and Disposition July 2016, 44 (7) 1027-1037; DOI: https://doi.org/10.1124/dmd.116.069344
  18. Suetterlin, Martina

    1. You have access
      New Insights in Tissue Distribution, Metabolism, and Excretion of [3H]-Labeled Antibody Maytansinoid Conjugates in Female Tumor-Bearing Nude Rats
      Markus Walles, Bettina Rudolph, Thierry Wolf, Julien Bourgailh, Martina Suetterlin, Thomas Moenius, Gisela Peraus, Olivier Heudi, Walid Elbast, Christian Lanshoeft and Sanela Bilic
      Drug Metabolism and Disposition July 2016, 44 (7) 897-910; DOI: https://doi.org/10.1124/dmd.115.069021
  19. Sun, Huadong

    1. You have access
      Metabolite Kinetics: The Segregated Flow Model for Intestinal and Whole Body Physiologically Based Pharmacokinetic Modeling to Describe Intestinal and Hepatic Glucuronidation of Morphine in Rats In Vivo
      Qi Joy Yang, Jianghong Fan, Shu Chen, Lutan Liu, Huadong Sun and K. Sandy Pang
      Drug Metabolism and Disposition July 2016, 44 (7) 1123-1138; DOI: https://doi.org/10.1124/dmd.116.069542
  20. Sun, Jianguo

    1. Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      You have access
      Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      Meijuan Xu, Haiping Hao, Lifeng Jiang, Yidan Wei, Fang Zhou, Jianguo Sun, Jingwei Zhang, Hui Ji, Guangji Wang, Wenzheng Ju and Ping Li
      Drug Metabolism and Disposition July 2016, 44 (7) 878-887; DOI: https://doi.org/10.1124/dmd.116.069914

T

  1. Thakker, Dhiren R.

    1. You have access
      Quantification of Flavin-containing Monooxygenases 1, 3, and 5 in Human Liver Microsomes by UPLC-MRM-Based Targeted Quantitative Proteomics and Its Application to the Study of Ontogeny
      Yao Chen, Nicole R. Zane, Dhiren R. Thakker and Michael Zhuo Wang
      Drug Metabolism and Disposition July 2016, 44 (7) 975-983; DOI: https://doi.org/10.1124/dmd.115.067538
  2. Thomson, Margaret M. S.

    1. You have access
      Expression Patterns of Organic Anion Transporting Polypeptides 1B1 and 1B3 Protein in Human Pediatric Liver
      Margaret M. S. Thomson, Ronald N. Hines, Erin G. Schuetz and Bernd Meibohm
      Drug Metabolism and Disposition July 2016, 44 (7) 999-1004; DOI: https://doi.org/10.1124/dmd.115.069252
  3. Tibboel, Dick

    1. You have access
      Human Intestinal PEPT1 Transporter Expression and Localization in Preterm and Term Infants
      Miriam G. Mooij, Barbara E. A. de Koning, Dicky J. Lindenbergh-Kortleve, Ytje Simons-Oosterhuis, Bianca D. van Groen, Dick Tibboel, Janneke N. Samsom and Saskia N. de Wildt
      Drug Metabolism and Disposition July 2016, 44 (7) 1014-1019; DOI: https://doi.org/10.1124/dmd.115.068809
    2. You have access
      Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life
      Miriam G. Mooij, Evita van de Steeg, Joost van Rosmalen, Jonathan D. Windster, Barbara A.E. de Koning, Wouter H. J. Vaes, Bianca D. van Groen, Dick Tibboel, Heleen M. Wortelboer and Saskia N. de Wildt
      Drug Metabolism and Disposition July 2016, 44 (7) 1005-1013; DOI: https://doi.org/10.1124/dmd.115.068577
  4. Toda, Akiko

    1. Individual Differences in Metabolic Clearance of <em>S</em>-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers
      You have access
      Individual Differences in Metabolic Clearance of S-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Mirai Kawano, Makiko Shimizu, Akiko Toda, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2016, 44 (7) 911-915; DOI: https://doi.org/10.1124/dmd.116.070383
  5. Tsuneyama, Koichi

    1. You have access
      Zomepirac Acyl Glucuronide Is Responsible for Zomepirac-Induced Acute Kidney Injury in Mice
      Atsushi Iwamura, Katsuhito Watanabe, Sho Akai, Tsubasa Nishinosono, Koichi Tsuneyama, Shingo Oda, Toshiyuki Kume and Tsuyoshi Yokoi
      Drug Metabolism and Disposition July 2016, 44 (7) 888-896; DOI: https://doi.org/10.1124/dmd.116.069575
  6. Twist, Greyson P.

    1. You have access
      Developmental Expression of CYP2B6: A Comprehensive Analysis of mRNA Expression, Protein Content and Bupropion Hydroxylase Activity and the Impact of Genetic Variation
      Robin E. Pearce, Roger Gaedigk, Greyson P. Twist, Hongying Dai, Amanda K. Riffel, J. Steven Leeder and Andrea Gaedigk
      Drug Metabolism and Disposition July 2016, 44 (7) 948-958; DOI: https://doi.org/10.1124/dmd.115.067546

U

  1. Uehara, Shotaro

    1. Individual Differences in Metabolic Clearance of <em>S</em>-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers
      You have access
      Individual Differences in Metabolic Clearance of S-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Mirai Kawano, Makiko Shimizu, Akiko Toda, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2016, 44 (7) 911-915; DOI: https://doi.org/10.1124/dmd.116.070383
  2. Uno, Yasuhiro

    1. Individual Differences in Metabolic Clearance of <em>S</em>-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers
      You have access
      Individual Differences in Metabolic Clearance of S-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Mirai Kawano, Makiko Shimizu, Akiko Toda, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2016, 44 (7) 911-915; DOI: https://doi.org/10.1124/dmd.116.070383
  3. Utoh, Masahiro

    1. Individual Differences in Metabolic Clearance of <em>S</em>-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers
      You have access
      Individual Differences in Metabolic Clearance of S-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Mirai Kawano, Makiko Shimizu, Akiko Toda, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2016, 44 (7) 911-915; DOI: https://doi.org/10.1124/dmd.116.070383

V

  1. Vaes, Wouter H. J.

    1. You have access
      Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life
      Miriam G. Mooij, Evita van de Steeg, Joost van Rosmalen, Jonathan D. Windster, Barbara A.E. de Koning, Wouter H. J. Vaes, Bianca D. van Groen, Dick Tibboel, Heleen M. Wortelboer and Saskia N. de Wildt
      Drug Metabolism and Disposition July 2016, 44 (7) 1005-1013; DOI: https://doi.org/10.1124/dmd.115.068577
  2. van de Steeg, Evita

    1. You have access
      Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life
      Miriam G. Mooij, Evita van de Steeg, Joost van Rosmalen, Jonathan D. Windster, Barbara A.E. de Koning, Wouter H. J. Vaes, Bianca D. van Groen, Dick Tibboel, Heleen M. Wortelboer and Saskia N. de Wildt
      Drug Metabolism and Disposition July 2016, 44 (7) 1005-1013; DOI: https://doi.org/10.1124/dmd.115.068577
  3. van Groen, Bianca D.

    1. You have access
      Human Intestinal PEPT1 Transporter Expression and Localization in Preterm and Term Infants
      Miriam G. Mooij, Barbara E. A. de Koning, Dicky J. Lindenbergh-Kortleve, Ytje Simons-Oosterhuis, Bianca D. van Groen, Dick Tibboel, Janneke N. Samsom and Saskia N. de Wildt
      Drug Metabolism and Disposition July 2016, 44 (7) 1014-1019; DOI: https://doi.org/10.1124/dmd.115.068809
    2. You have access
      Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life
      Miriam G. Mooij, Evita van de Steeg, Joost van Rosmalen, Jonathan D. Windster, Barbara A.E. de Koning, Wouter H. J. Vaes, Bianca D. van Groen, Dick Tibboel, Heleen M. Wortelboer and Saskia N. de Wildt
      Drug Metabolism and Disposition July 2016, 44 (7) 1005-1013; DOI: https://doi.org/10.1124/dmd.115.068577
  4. Van Haandel, Leon

    1. You have access
      Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children
      Jean C. Dinh, Robin E. Pearce, Leon Van Haandel, Andrea Gaedigk and J. Steven Leeder
      Drug Metabolism and Disposition July 2016, 44 (7) 1070-1079; DOI: https://doi.org/10.1124/dmd.116.069518
  5. van Rosmalen, Joost

    1. You have access
      Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life
      Miriam G. Mooij, Evita van de Steeg, Joost van Rosmalen, Jonathan D. Windster, Barbara A.E. de Koning, Wouter H. J. Vaes, Bianca D. van Groen, Dick Tibboel, Heleen M. Wortelboer and Saskia N. de Wildt
      Drug Metabolism and Disposition July 2016, 44 (7) 1005-1013; DOI: https://doi.org/10.1124/dmd.115.068577
  6. Vyhlidal, Carrie

    1. Open Access
      Decreased Pregnane X Receptor Expression in Children with Active Crohn’s Disease
      Valentina Shakhnovich, Carrie Vyhlidal, Craig Friesen, Amber Hildreth, Vivekanand Singh, James Daniel, Gregory L. Kearns and J. Steven Leeder
      Drug Metabolism and Disposition July 2016, 44 (7) 1066-1069; DOI: https://doi.org/10.1124/dmd.115.068742
  7. Vyhlidal, Carrie A.

    1. You have access
      Dynamics of Cytosine Methylation in the Proximal Promoters of CYP3A4 and CYP3A7 in Pediatric and Prenatal Livers
      Carrie A. Vyhlidal, Chengpeng Bi, Shui Qing Ye and J. Steven Leeder
      Drug Metabolism and Disposition July 2016, 44 (7) 1020-1026; DOI: https://doi.org/10.1124/dmd.115.068726

W

  1. Walles, Markus

    1. You have access
      New Insights in Tissue Distribution, Metabolism, and Excretion of [3H]-Labeled Antibody Maytansinoid Conjugates in Female Tumor-Bearing Nude Rats
      Markus Walles, Bettina Rudolph, Thierry Wolf, Julien Bourgailh, Martina Suetterlin, Thomas Moenius, Gisela Peraus, Olivier Heudi, Walid Elbast, Christian Lanshoeft and Sanela Bilic
      Drug Metabolism and Disposition July 2016, 44 (7) 897-910; DOI: https://doi.org/10.1124/dmd.115.069021
  2. Wang, Guangji

    1. Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      You have access
      Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      Meijuan Xu, Haiping Hao, Lifeng Jiang, Yidan Wei, Fang Zhou, Jianguo Sun, Jingwei Zhang, Hui Ji, Guangji Wang, Wenzheng Ju and Ping Li
      Drug Metabolism and Disposition July 2016, 44 (7) 878-887; DOI: https://doi.org/10.1124/dmd.116.069914
  3. Wang, Michael Zhuo

    1. You have access
      Quantification of Flavin-containing Monooxygenases 1, 3, and 5 in Human Liver Microsomes by UPLC-MRM-Based Targeted Quantitative Proteomics and Its Application to the Study of Ontogeny
      Yao Chen, Nicole R. Zane, Dhiren R. Thakker and Michael Zhuo Wang
      Drug Metabolism and Disposition July 2016, 44 (7) 975-983; DOI: https://doi.org/10.1124/dmd.115.067538
  4. Watanabe, Katsuhito

    1. You have access
      Zomepirac Acyl Glucuronide Is Responsible for Zomepirac-Induced Acute Kidney Injury in Mice
      Atsushi Iwamura, Katsuhito Watanabe, Sho Akai, Tsubasa Nishinosono, Koichi Tsuneyama, Shingo Oda, Toshiyuki Kume and Tsuyoshi Yokoi
      Drug Metabolism and Disposition July 2016, 44 (7) 888-896; DOI: https://doi.org/10.1124/dmd.116.069575
  5. Waters, Nigel J.

    1. You have access
      Physiologically Based Pharmacokinetic Modeling in Pediatric Oncology Drug Development
      Nathalie Rioux and Nigel J. Waters
      Drug Metabolism and Disposition July 2016, 44 (7) 934-943; DOI: https://doi.org/10.1124/dmd.115.068031
  6. Webb-Robertson, Bobbie-Jo

    1. Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development
      You have access
      Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development
      Natalie C. Sadler, Premchendar Nandhikonda, Bobbie-Jo Webb-Robertson, Charles Ansong, Lindsey N. Anderson, Jordan N. Smith, Richard A. Corley and Aaron T. Wright
      Drug Metabolism and Disposition July 2016, 44 (7) 984-991; DOI: https://doi.org/10.1124/dmd.115.068593
  7. Wei, Yidan

    1. Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      You have access
      Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      Meijuan Xu, Haiping Hao, Lifeng Jiang, Yidan Wei, Fang Zhou, Jianguo Sun, Jingwei Zhang, Hui Ji, Guangji Wang, Wenzheng Ju and Ping Li
      Drug Metabolism and Disposition July 2016, 44 (7) 878-887; DOI: https://doi.org/10.1124/dmd.116.069914
  8. Windster, Jonathan D.

    1. You have access
      Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life
      Miriam G. Mooij, Evita van de Steeg, Joost van Rosmalen, Jonathan D. Windster, Barbara A.E. de Koning, Wouter H. J. Vaes, Bianca D. van Groen, Dick Tibboel, Heleen M. Wortelboer and Saskia N. de Wildt
      Drug Metabolism and Disposition July 2016, 44 (7) 1005-1013; DOI: https://doi.org/10.1124/dmd.115.068577
  9. Wolf, Thierry

    1. You have access
      New Insights in Tissue Distribution, Metabolism, and Excretion of [3H]-Labeled Antibody Maytansinoid Conjugates in Female Tumor-Bearing Nude Rats
      Markus Walles, Bettina Rudolph, Thierry Wolf, Julien Bourgailh, Martina Suetterlin, Thomas Moenius, Gisela Peraus, Olivier Heudi, Walid Elbast, Christian Lanshoeft and Sanela Bilic
      Drug Metabolism and Disposition July 2016, 44 (7) 897-910; DOI: https://doi.org/10.1124/dmd.115.069021
  10. Wortelboer, Heleen M.

    1. You have access
      Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life
      Miriam G. Mooij, Evita van de Steeg, Joost van Rosmalen, Jonathan D. Windster, Barbara A.E. de Koning, Wouter H. J. Vaes, Bianca D. van Groen, Dick Tibboel, Heleen M. Wortelboer and Saskia N. de Wildt
      Drug Metabolism and Disposition July 2016, 44 (7) 1005-1013; DOI: https://doi.org/10.1124/dmd.115.068577
  11. Wright, Aaron T.

    1. Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development
      You have access
      Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development
      Natalie C. Sadler, Premchendar Nandhikonda, Bobbie-Jo Webb-Robertson, Charles Ansong, Lindsey N. Anderson, Jordan N. Smith, Richard A. Corley and Aaron T. Wright
      Drug Metabolism and Disposition July 2016, 44 (7) 984-991; DOI: https://doi.org/10.1124/dmd.115.068593

X

  1. Xu, Meijuan

    1. Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      You have access
      Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      Meijuan Xu, Haiping Hao, Lifeng Jiang, Yidan Wei, Fang Zhou, Jianguo Sun, Jingwei Zhang, Hui Ji, Guangji Wang, Wenzheng Ju and Ping Li
      Drug Metabolism and Disposition July 2016, 44 (7) 878-887; DOI: https://doi.org/10.1124/dmd.116.069914

Y

  1. Yamazaki, Hiroshi

    1. Individual Differences in Metabolic Clearance of <em>S</em>-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers
      You have access
      Individual Differences in Metabolic Clearance of S-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Mirai Kawano, Makiko Shimizu, Akiko Toda, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2016, 44 (7) 911-915; DOI: https://doi.org/10.1124/dmd.116.070383
  2. Yan, Ke

    1. You have access
      Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny
      Nicholas L. Giebel, Jeffrey D. Shadley, D. Gail McCarver, Kenneth Dorko, Roberto Gramignoli, Stephen C. Strom, Ke Yan, Pippa M. Simpson and Ronald N. Hines
      Drug Metabolism and Disposition July 2016, 44 (7) 1027-1037; DOI: https://doi.org/10.1124/dmd.116.069344
  3. Yang, Qi Joy

    1. You have access
      Metabolite Kinetics: The Segregated Flow Model for Intestinal and Whole Body Physiologically Based Pharmacokinetic Modeling to Describe Intestinal and Hepatic Glucuronidation of Morphine in Rats In Vivo
      Qi Joy Yang, Jianghong Fan, Shu Chen, Lutan Liu, Huadong Sun and K. Sandy Pang
      Drug Metabolism and Disposition July 2016, 44 (7) 1123-1138; DOI: https://doi.org/10.1124/dmd.116.069542
  4. Ye, Shui Qing

    1. You have access
      Dynamics of Cytosine Methylation in the Proximal Promoters of CYP3A4 and CYP3A7 in Pediatric and Prenatal Livers
      Carrie A. Vyhlidal, Chengpeng Bi, Shui Qing Ye and J. Steven Leeder
      Drug Metabolism and Disposition July 2016, 44 (7) 1020-1026; DOI: https://doi.org/10.1124/dmd.115.068726
  5. Yokoi, Tsuyoshi

    1. You have access
      Zomepirac Acyl Glucuronide Is Responsible for Zomepirac-Induced Acute Kidney Injury in Mice
      Atsushi Iwamura, Katsuhito Watanabe, Sho Akai, Tsubasa Nishinosono, Koichi Tsuneyama, Shingo Oda, Toshiyuki Kume and Tsuyoshi Yokoi
      Drug Metabolism and Disposition July 2016, 44 (7) 888-896; DOI: https://doi.org/10.1124/dmd.116.069575
  6. Yu, Jingyu

    1. You have access
      Role of Quantitative Clinical Pharmacology in Pediatric Approval and Labeling
      Nitin Mehrotra, Atul Bhattaram, Justin C. Earp, Jeffry Florian, Kevin Krudys, Jee Eun Lee, Joo Yeon Lee, Jiang Liu, Yeruk Mulugeta, Jingyu Yu, Ping Zhao and Vikram Sinha
      Drug Metabolism and Disposition July 2016, 44 (7) 924-933; DOI: https://doi.org/10.1124/dmd.116.069559

Z

  1. Zane, Nicole R.

    1. You have access
      Quantification of Flavin-containing Monooxygenases 1, 3, and 5 in Human Liver Microsomes by UPLC-MRM-Based Targeted Quantitative Proteomics and Its Application to the Study of Ontogeny
      Yao Chen, Nicole R. Zane, Dhiren R. Thakker and Michael Zhuo Wang
      Drug Metabolism and Disposition July 2016, 44 (7) 975-983; DOI: https://doi.org/10.1124/dmd.115.067538
  2. Zhang, Jingwei

    1. Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
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      Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      Meijuan Xu, Haiping Hao, Lifeng Jiang, Yidan Wei, Fang Zhou, Jianguo Sun, Jingwei Zhang, Hui Ji, Guangji Wang, Wenzheng Ju and Ping Li
      Drug Metabolism and Disposition July 2016, 44 (7) 878-887; DOI: https://doi.org/10.1124/dmd.116.069914
  3. Zhao, Ping

    1. You have access
      Role of Quantitative Clinical Pharmacology in Pediatric Approval and Labeling
      Nitin Mehrotra, Atul Bhattaram, Justin C. Earp, Jeffry Florian, Kevin Krudys, Jee Eun Lee, Joo Yeon Lee, Jiang Liu, Yeruk Mulugeta, Jingyu Yu, Ping Zhao and Vikram Sinha
      Drug Metabolism and Disposition July 2016, 44 (7) 924-933; DOI: https://doi.org/10.1124/dmd.116.069559
  4. Zhou, Fang

    1. Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      You have access
      Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats
      Meijuan Xu, Haiping Hao, Lifeng Jiang, Yidan Wei, Fang Zhou, Jianguo Sun, Jingwei Zhang, Hui Ji, Guangji Wang, Wenzheng Ju and Ping Li
      Drug Metabolism and Disposition July 2016, 44 (7) 878-887; DOI: https://doi.org/10.1124/dmd.116.069914
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Drug Metabolism and Disposition: 44 (7)
Drug Metabolism and Disposition
Vol. 44, Issue 7
1 Jul 2016
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
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