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Research ArticleSpecial Section on Pediatric Drug Disposition and Pharmacokinetics

How Does In Vivo Biliary Elimination of Drugs Change with Age? Evidence from In Vitro and Clinical Data Using a Systems Pharmacology Approach

Trevor N. Johnson, Masoud Jamei and Karen Rowland-Yeo
Drug Metabolism and Disposition July 2016, 44 (7) 1090-1098; DOI: https://doi.org/10.1124/dmd.115.068643

Article Information

vol. 44 no. 7 1090-1098
DOI 
https://doi.org/10.1124/dmd.115.068643
PubMed 
26862026
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received November 30, 2015
  • Accepted February 8, 2016
  • Published online June 14, 2016.

Article Versions

Copyright & Usage 
Copyright © 2016 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Trevor N. Johnson,
  2. Masoud Jamei, and
  3. Karen Rowland-Yeo
  1. Simcyp Limited (a Certara company), Sheffield, United Kingdom
  1. Address correspondence to:
    Dr. Trevor N. Johnson, Simcyp Limited (a Certara Company), Blades Enterprise Centre, John Street, Sheffield, S2 4SU, UK. E-mail: trevor.johnson{at}certara.com
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Research ArticleSpecial Section on Pediatric Drug Disposition and Pharmacokinetics

In Vivo Ontogeny of Biliary Elimination

Trevor N. Johnson, Masoud Jamei and Karen Rowland-Yeo
Drug Metabolism and Disposition July 1, 2016, 44 (7) 1090-1098; DOI: https://doi.org/10.1124/dmd.115.068643
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