Table of Contents

Articles

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  Arylsulfatase B Mediates the Sulfonation-Transport Interplay in Human Embryonic Kidney 293 Cells Overexpressing Sulfotransferase 1A3

  Mengjing Zhao, Shuai Wang, Feng Li, Dong Dong and Baojian Wu

  Drug Metabolism and Disposition September 2016, 44 (9) 1441-1449; DOI: https://doi.org/10.1124/dmd.116.070938
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  The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women

  Stefan Zajic, Stefaan Rossenu, David Hreniuk, Filippos Kesisoglou, Jacqueline McCrea, Fang Liu, Li Sun, Rose Witter, Don Gauthier, Roy Helmy, Darrick Joss, Tong Ni, Randall Stoltz, Julie Stone and S. Aubrey Stoch

  Drug Metabolism and Disposition September 2016, 44 (9) 1450-1458; DOI: https://doi.org/10.1124/dmd.116.069906
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  Contextualizing Hepatocyte Functionality of Cryopreserved HepaRG Cell Cultures

  Jonathan P. Jackson, Linhou Li, Erica D. Chamberlain, Hongbing Wang and Stephen S. Ferguson

  Drug Metabolism and Disposition September 2016, 44 (9) 1463-1479; DOI: https://doi.org/10.1124/dmd.116.069831
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  CYP3A Specifically Catalyzes 1β-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity

  Martin A. Hayes, Xue-Qing Li, Gunnar Grönberg, Ulf Diczfalusy and Tommy B. Andersson

  Drug Metabolism and Disposition September 2016, 44 (9) 1480-1489; DOI: https://doi.org/10.1124/dmd.116.070805
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  Evaluation of Clopidogrel Conjugation Metabolism: PK Studies in Man and Mice of Clopidogrel Acyl Glucuronide

  Simona Nicoleta Savu, Luigi Silvestro, Mariana Surmeian, Lina Remis, Yuksel Rasit, Simona Rizea Savu and Constantin Mircioiu

  Drug Metabolism and Disposition September 2016, 44 (9) 1490-1497; DOI: https://doi.org/10.1124/dmd.116.071092
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  Identification of Genetic Polymorphisms of CYP2W1 in the Three Main Chinese Ethnicities: Han, Tibetan, and Uighur

  Yanwei Li, Xing Kang, Ge Yang, Penggao Dai, Chao Chen and Huijuan Wang

  Drug Metabolism and Disposition September 2016, 44 (9) 1510-1515; DOI: https://doi.org/10.1124/dmd.115.069153
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  Chemical Structure and Concentration of Intratumor Catabolites Determine Efficacy of Antibody Drug Conjugates

  Donglu Zhang, Shang-Fan Yu, Yong Ma, Keyang Xu, Peter S. Dragovich, Thomas H. Pillow, Luna Liu, Geoffrey Del Rosario, Jintang He, Zhonghua Pei, Jack D. Sadowsky, Hans K. Erickson, Cornelis E. C. A. Hop and S. Cyrus Khojasteh

  Drug Metabolism and Disposition September 2016, 44 (9) 1517-1523; DOI: https://doi.org/10.1124/dmd.116.070631
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  Functional Integrity of the Chimeric (Humanized) Mouse Liver: Enzyme Zonation, Physiologic Spaces, and Hepatic Enzymes and Transporters

  Edwin C. Y. Chow, Jason Z. Y. Wang, Holly P. Quach, Hui Tang, David C. Evans, Albert P. Li, Jose Silva and K. Sandy Pang

  Drug Metabolism and Disposition September 2016, 44 (9) 1524-1535; DOI: https://doi.org/10.1124/dmd.116.070060
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  Occupancy of Nociceptin/Orphanin FQ Peptide Receptors by the Antagonist LY2940094 in Rats and Healthy Human Subjects

  Eyas Raddad, Amy Chappell, Jeffery Meyer, Alan Wilson, Charles E. Ruegg, Johannes Tauscher, Michael A. Statnick, Vanessa Barth, Xin Zhang and Steven J. Verfaille

  Drug Metabolism and Disposition September 2016, 44 (9) 1536-1542; DOI: https://doi.org/10.1124/dmd.116.070359