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Index by author

September 01, 2016; Volume 44,Issue 9

A

  1. Andersson, Tommy B.

    1. CYP3A Specifically Catalyzes 1<em>β</em>-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity
      CYP3A Specifically Catalyzes 1β-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity
      Martin A. Hayes, Xue-Qing Li, Gunnar Grönberg, Ulf Diczfalusy and Tommy B. Andersson
      Drug Metabolism and Disposition September 2016, 44 (9) 1480-1489; DOI: https://doi.org/10.1124/dmd.116.070805

B

  1. Barth, Vanessa

    1. Occupancy of Nociceptin/Orphanin FQ Peptide Receptors by the Antagonist LY2940094 in Rats and Healthy Human Subjects
      Eyas Raddad, Amy Chappell, Jeffery Meyer, Alan Wilson, Charles E. Ruegg, Johannes Tauscher, Michael A. Statnick, Vanessa Barth, Xin Zhang and Steven J. Verfaille
      Drug Metabolism and Disposition September 2016, 44 (9) 1536-1542; DOI: https://doi.org/10.1124/dmd.116.070359

  2. Bleasby, Kelly

    1. The Complexities of Interpreting Reversible Elevated Serum Creatinine Levels in Drug Development: Does a Correlation with Inhibition of Renal Transporters Exist?
      Xiaoyan Chu, Kelly Bleasby, Grace Hoyee Chan, Irene Nunes and Raymond Evers
      Drug Metabolism and Disposition September 2016, 44 (9) 1498-1509; DOI: https://doi.org/10.1124/dmd.115.067694

C

  1. Chamberlain, Erica D.

    1. Contextualizing Hepatocyte Functionality of Cryopreserved HepaRG Cell Cultures
      Jonathan P. Jackson, Linhou Li, Erica D. Chamberlain, Hongbing Wang and Stephen S. Ferguson
      Drug Metabolism and Disposition September 2016, 44 (9) 1463-1479; DOI: https://doi.org/10.1124/dmd.116.069831

  2. Chan, Grace Hoyee

    1. The Complexities of Interpreting Reversible Elevated Serum Creatinine Levels in Drug Development: Does a Correlation with Inhibition of Renal Transporters Exist?
      Xiaoyan Chu, Kelly Bleasby, Grace Hoyee Chan, Irene Nunes and Raymond Evers
      Drug Metabolism and Disposition September 2016, 44 (9) 1498-1509; DOI: https://doi.org/10.1124/dmd.115.067694

  3. Chappell, Amy

    1. Occupancy of Nociceptin/Orphanin FQ Peptide Receptors by the Antagonist LY2940094 in Rats and Healthy Human Subjects
      Eyas Raddad, Amy Chappell, Jeffery Meyer, Alan Wilson, Charles E. Ruegg, Johannes Tauscher, Michael A. Statnick, Vanessa Barth, Xin Zhang and Steven J. Verfaille
      Drug Metabolism and Disposition September 2016, 44 (9) 1536-1542; DOI: https://doi.org/10.1124/dmd.116.070359

  4. Chen, Chao

    1. Identification of Genetic Polymorphisms of CYP2W1 in the Three Main Chinese Ethnicities: Han, Tibetan, and Uighur
      Yanwei Li, Xing Kang, Ge Yang, Penggao Dai, Chao Chen and Huijuan Wang
      Drug Metabolism and Disposition September 2016, 44 (9) 1510-1515; DOI: https://doi.org/10.1124/dmd.115.069153

  5. Chow, Edwin C. Y.

    1. Functional Integrity of the Chimeric (Humanized) Mouse Liver: Enzyme Zonation, Physiologic Spaces, and Hepatic Enzymes and Transporters
      Edwin C. Y. Chow, Jason Z. Y. Wang, Holly P. Quach, Hui Tang, David C. Evans, Albert P. Li, Jose Silva and K. Sandy Pang
      Drug Metabolism and Disposition September 2016, 44 (9) 1524-1535; DOI: https://doi.org/10.1124/dmd.116.070060

  6. Chu, Xiaoyan

    1. The Complexities of Interpreting Reversible Elevated Serum Creatinine Levels in Drug Development: Does a Correlation with Inhibition of Renal Transporters Exist?
      Xiaoyan Chu, Kelly Bleasby, Grace Hoyee Chan, Irene Nunes and Raymond Evers
      Drug Metabolism and Disposition September 2016, 44 (9) 1498-1509; DOI: https://doi.org/10.1124/dmd.115.067694

D

  1. Dai, Penggao

    1. Identification of Genetic Polymorphisms of CYP2W1 in the Three Main Chinese Ethnicities: Han, Tibetan, and Uighur
      Yanwei Li, Xing Kang, Ge Yang, Penggao Dai, Chao Chen and Huijuan Wang
      Drug Metabolism and Disposition September 2016, 44 (9) 1510-1515; DOI: https://doi.org/10.1124/dmd.115.069153

  2. Del Rosario, Geoffrey

    1. Open Access
      Chemical Structure and Concentration of Intratumor Catabolites Determine Efficacy of Antibody Drug Conjugates
      Donglu Zhang, Shang-Fan Yu, Yong Ma, Keyang Xu, Peter S. Dragovich, Thomas H. Pillow, Luna Liu, Geoffrey Del Rosario, Jintang He, Zhonghua Pei, Jack D. Sadowsky, Hans K. Erickson, Cornelis E. C. A. Hop and S. Cyrus Khojasteh
      Drug Metabolism and Disposition September 2016, 44 (9) 1517-1523; DOI: https://doi.org/10.1124/dmd.116.070631

  3. Diczfalusy, Ulf

    1. CYP3A Specifically Catalyzes 1<em>β</em>-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity
      CYP3A Specifically Catalyzes 1β-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity
      Martin A. Hayes, Xue-Qing Li, Gunnar Grönberg, Ulf Diczfalusy and Tommy B. Andersson
      Drug Metabolism and Disposition September 2016, 44 (9) 1480-1489; DOI: https://doi.org/10.1124/dmd.116.070805

  4. Dong, Dong

    1. Arylsulfatase B Mediates the Sulfonation-Transport Interplay in Human Embryonic Kidney 293 Cells Overexpressing Sulfotransferase 1A3
      Mengjing Zhao, Shuai Wang, Feng Li, Dong Dong and Baojian Wu
      Drug Metabolism and Disposition September 2016, 44 (9) 1441-1449; DOI: https://doi.org/10.1124/dmd.116.070938

  5. Dragovich, Peter S.

    1. Open Access
      Chemical Structure and Concentration of Intratumor Catabolites Determine Efficacy of Antibody Drug Conjugates
      Donglu Zhang, Shang-Fan Yu, Yong Ma, Keyang Xu, Peter S. Dragovich, Thomas H. Pillow, Luna Liu, Geoffrey Del Rosario, Jintang He, Zhonghua Pei, Jack D. Sadowsky, Hans K. Erickson, Cornelis E. C. A. Hop and S. Cyrus Khojasteh
      Drug Metabolism and Disposition September 2016, 44 (9) 1517-1523; DOI: https://doi.org/10.1124/dmd.116.070631

E

  1. Erickson, Hans K.

    1. Open Access
      Chemical Structure and Concentration of Intratumor Catabolites Determine Efficacy of Antibody Drug Conjugates
      Donglu Zhang, Shang-Fan Yu, Yong Ma, Keyang Xu, Peter S. Dragovich, Thomas H. Pillow, Luna Liu, Geoffrey Del Rosario, Jintang He, Zhonghua Pei, Jack D. Sadowsky, Hans K. Erickson, Cornelis E. C. A. Hop and S. Cyrus Khojasteh
      Drug Metabolism and Disposition September 2016, 44 (9) 1517-1523; DOI: https://doi.org/10.1124/dmd.116.070631

  2. Evans, David C.

    1. Functional Integrity of the Chimeric (Humanized) Mouse Liver: Enzyme Zonation, Physiologic Spaces, and Hepatic Enzymes and Transporters
      Edwin C. Y. Chow, Jason Z. Y. Wang, Holly P. Quach, Hui Tang, David C. Evans, Albert P. Li, Jose Silva and K. Sandy Pang
      Drug Metabolism and Disposition September 2016, 44 (9) 1524-1535; DOI: https://doi.org/10.1124/dmd.116.070060

  3. Evers, Raymond

    1. The Complexities of Interpreting Reversible Elevated Serum Creatinine Levels in Drug Development: Does a Correlation with Inhibition of Renal Transporters Exist?
      Xiaoyan Chu, Kelly Bleasby, Grace Hoyee Chan, Irene Nunes and Raymond Evers
      Drug Metabolism and Disposition September 2016, 44 (9) 1498-1509; DOI: https://doi.org/10.1124/dmd.115.067694

F

  1. Ferguson, Stephen S.

    1. Contextualizing Hepatocyte Functionality of Cryopreserved HepaRG Cell Cultures
      Jonathan P. Jackson, Linhou Li, Erica D. Chamberlain, Hongbing Wang and Stephen S. Ferguson
      Drug Metabolism and Disposition September 2016, 44 (9) 1463-1479; DOI: https://doi.org/10.1124/dmd.116.069831

G

  1. Gauthier, Don

    1. The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women
      Stefan Zajic, Stefaan Rossenu, David Hreniuk, Filippos Kesisoglou, Jacqueline McCrea, Fang Liu, Li Sun, Rose Witter, Don Gauthier, Roy Helmy, Darrick Joss, Tong Ni, Randall Stoltz, Julie Stone and S. Aubrey Stoch
      Drug Metabolism and Disposition September 2016, 44 (9) 1450-1458; DOI: https://doi.org/10.1124/dmd.116.069906

  2. Grönberg, Gunnar

    1. CYP3A Specifically Catalyzes 1<em>β</em>-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity
      CYP3A Specifically Catalyzes 1β-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity
      Martin A. Hayes, Xue-Qing Li, Gunnar Grönberg, Ulf Diczfalusy and Tommy B. Andersson
      Drug Metabolism and Disposition September 2016, 44 (9) 1480-1489; DOI: https://doi.org/10.1124/dmd.116.070805

H

  1. Hayes, Martin A.

    1. CYP3A Specifically Catalyzes 1<em>β</em>-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity
      CYP3A Specifically Catalyzes 1β-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity
      Martin A. Hayes, Xue-Qing Li, Gunnar Grönberg, Ulf Diczfalusy and Tommy B. Andersson
      Drug Metabolism and Disposition September 2016, 44 (9) 1480-1489; DOI: https://doi.org/10.1124/dmd.116.070805

  2. He, Jintang

    1. Open Access
      Chemical Structure and Concentration of Intratumor Catabolites Determine Efficacy of Antibody Drug Conjugates
      Donglu Zhang, Shang-Fan Yu, Yong Ma, Keyang Xu, Peter S. Dragovich, Thomas H. Pillow, Luna Liu, Geoffrey Del Rosario, Jintang He, Zhonghua Pei, Jack D. Sadowsky, Hans K. Erickson, Cornelis E. C. A. Hop and S. Cyrus Khojasteh
      Drug Metabolism and Disposition September 2016, 44 (9) 1517-1523; DOI: https://doi.org/10.1124/dmd.116.070631

  3. Helmy, Roy

    1. The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women
      Stefan Zajic, Stefaan Rossenu, David Hreniuk, Filippos Kesisoglou, Jacqueline McCrea, Fang Liu, Li Sun, Rose Witter, Don Gauthier, Roy Helmy, Darrick Joss, Tong Ni, Randall Stoltz, Julie Stone and S. Aubrey Stoch
      Drug Metabolism and Disposition September 2016, 44 (9) 1450-1458; DOI: https://doi.org/10.1124/dmd.116.069906

  4. Hop, Cornelis E. C. A.

    1. Open Access
      Chemical Structure and Concentration of Intratumor Catabolites Determine Efficacy of Antibody Drug Conjugates
      Donglu Zhang, Shang-Fan Yu, Yong Ma, Keyang Xu, Peter S. Dragovich, Thomas H. Pillow, Luna Liu, Geoffrey Del Rosario, Jintang He, Zhonghua Pei, Jack D. Sadowsky, Hans K. Erickson, Cornelis E. C. A. Hop and S. Cyrus Khojasteh
      Drug Metabolism and Disposition September 2016, 44 (9) 1517-1523; DOI: https://doi.org/10.1124/dmd.116.070631

  5. Hreniuk, David

    1. The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women
      Stefan Zajic, Stefaan Rossenu, David Hreniuk, Filippos Kesisoglou, Jacqueline McCrea, Fang Liu, Li Sun, Rose Witter, Don Gauthier, Roy Helmy, Darrick Joss, Tong Ni, Randall Stoltz, Julie Stone and S. Aubrey Stoch
      Drug Metabolism and Disposition September 2016, 44 (9) 1450-1458; DOI: https://doi.org/10.1124/dmd.116.069906

J

  1. Jackson, Jonathan P.

    1. Contextualizing Hepatocyte Functionality of Cryopreserved HepaRG Cell Cultures
      Jonathan P. Jackson, Linhou Li, Erica D. Chamberlain, Hongbing Wang and Stephen S. Ferguson
      Drug Metabolism and Disposition September 2016, 44 (9) 1463-1479; DOI: https://doi.org/10.1124/dmd.116.069831

  2. Joss, Darrick

    1. The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women
      Stefan Zajic, Stefaan Rossenu, David Hreniuk, Filippos Kesisoglou, Jacqueline McCrea, Fang Liu, Li Sun, Rose Witter, Don Gauthier, Roy Helmy, Darrick Joss, Tong Ni, Randall Stoltz, Julie Stone and S. Aubrey Stoch
      Drug Metabolism and Disposition September 2016, 44 (9) 1450-1458; DOI: https://doi.org/10.1124/dmd.116.069906

K

  1. Kang, Xing

    1. Identification of Genetic Polymorphisms of CYP2W1 in the Three Main Chinese Ethnicities: Han, Tibetan, and Uighur
      Yanwei Li, Xing Kang, Ge Yang, Penggao Dai, Chao Chen and Huijuan Wang
      Drug Metabolism and Disposition September 2016, 44 (9) 1510-1515; DOI: https://doi.org/10.1124/dmd.115.069153

  2. Kesisoglou, Filippos

    1. The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women
      Stefan Zajic, Stefaan Rossenu, David Hreniuk, Filippos Kesisoglou, Jacqueline McCrea, Fang Liu, Li Sun, Rose Witter, Don Gauthier, Roy Helmy, Darrick Joss, Tong Ni, Randall Stoltz, Julie Stone and S. Aubrey Stoch
      Drug Metabolism and Disposition September 2016, 44 (9) 1450-1458; DOI: https://doi.org/10.1124/dmd.116.069906

  3. Khojasteh, S. Cyrus

    1. Open Access
      Chemical Structure and Concentration of Intratumor Catabolites Determine Efficacy of Antibody Drug Conjugates
      Donglu Zhang, Shang-Fan Yu, Yong Ma, Keyang Xu, Peter S. Dragovich, Thomas H. Pillow, Luna Liu, Geoffrey Del Rosario, Jintang He, Zhonghua Pei, Jack D. Sadowsky, Hans K. Erickson, Cornelis E. C. A. Hop and S. Cyrus Khojasteh
      Drug Metabolism and Disposition September 2016, 44 (9) 1517-1523; DOI: https://doi.org/10.1124/dmd.116.070631

L

  1. Li, Albert P.

    1. Functional Integrity of the Chimeric (Humanized) Mouse Liver: Enzyme Zonation, Physiologic Spaces, and Hepatic Enzymes and Transporters
      Edwin C. Y. Chow, Jason Z. Y. Wang, Holly P. Quach, Hui Tang, David C. Evans, Albert P. Li, Jose Silva and K. Sandy Pang
      Drug Metabolism and Disposition September 2016, 44 (9) 1524-1535; DOI: https://doi.org/10.1124/dmd.116.070060

  2. Li, Feng

    1. Arylsulfatase B Mediates the Sulfonation-Transport Interplay in Human Embryonic Kidney 293 Cells Overexpressing Sulfotransferase 1A3
      Mengjing Zhao, Shuai Wang, Feng Li, Dong Dong and Baojian Wu
      Drug Metabolism and Disposition September 2016, 44 (9) 1441-1449; DOI: https://doi.org/10.1124/dmd.116.070938

  3. Li, Linhou

    1. Contextualizing Hepatocyte Functionality of Cryopreserved HepaRG Cell Cultures
      Jonathan P. Jackson, Linhou Li, Erica D. Chamberlain, Hongbing Wang and Stephen S. Ferguson
      Drug Metabolism and Disposition September 2016, 44 (9) 1463-1479; DOI: https://doi.org/10.1124/dmd.116.069831

  4. Li, Xue-Qing

    1. CYP3A Specifically Catalyzes 1<em>β</em>-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity
      CYP3A Specifically Catalyzes 1β-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity
      Martin A. Hayes, Xue-Qing Li, Gunnar Grönberg, Ulf Diczfalusy and Tommy B. Andersson
      Drug Metabolism and Disposition September 2016, 44 (9) 1480-1489; DOI: https://doi.org/10.1124/dmd.116.070805

  5. Li, Yanwei

    1. Identification of Genetic Polymorphisms of CYP2W1 in the Three Main Chinese Ethnicities: Han, Tibetan, and Uighur
      Yanwei Li, Xing Kang, Ge Yang, Penggao Dai, Chao Chen and Huijuan Wang
      Drug Metabolism and Disposition September 2016, 44 (9) 1510-1515; DOI: https://doi.org/10.1124/dmd.115.069153

  6. Liu, Fang

    1. The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women
      Stefan Zajic, Stefaan Rossenu, David Hreniuk, Filippos Kesisoglou, Jacqueline McCrea, Fang Liu, Li Sun, Rose Witter, Don Gauthier, Roy Helmy, Darrick Joss, Tong Ni, Randall Stoltz, Julie Stone and S. Aubrey Stoch
      Drug Metabolism and Disposition September 2016, 44 (9) 1450-1458; DOI: https://doi.org/10.1124/dmd.116.069906

  7. Liu, Luna

    1. Open Access
      Chemical Structure and Concentration of Intratumor Catabolites Determine Efficacy of Antibody Drug Conjugates
      Donglu Zhang, Shang-Fan Yu, Yong Ma, Keyang Xu, Peter S. Dragovich, Thomas H. Pillow, Luna Liu, Geoffrey Del Rosario, Jintang He, Zhonghua Pei, Jack D. Sadowsky, Hans K. Erickson, Cornelis E. C. A. Hop and S. Cyrus Khojasteh
      Drug Metabolism and Disposition September 2016, 44 (9) 1517-1523; DOI: https://doi.org/10.1124/dmd.116.070631

M

  1. Ma, Yong

    1. Open Access
      Chemical Structure and Concentration of Intratumor Catabolites Determine Efficacy of Antibody Drug Conjugates
      Donglu Zhang, Shang-Fan Yu, Yong Ma, Keyang Xu, Peter S. Dragovich, Thomas H. Pillow, Luna Liu, Geoffrey Del Rosario, Jintang He, Zhonghua Pei, Jack D. Sadowsky, Hans K. Erickson, Cornelis E. C. A. Hop and S. Cyrus Khojasteh
      Drug Metabolism and Disposition September 2016, 44 (9) 1517-1523; DOI: https://doi.org/10.1124/dmd.116.070631

  2. McCrea, Jacqueline

    1. The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women
      Stefan Zajic, Stefaan Rossenu, David Hreniuk, Filippos Kesisoglou, Jacqueline McCrea, Fang Liu, Li Sun, Rose Witter, Don Gauthier, Roy Helmy, Darrick Joss, Tong Ni, Randall Stoltz, Julie Stone and S. Aubrey Stoch
      Drug Metabolism and Disposition September 2016, 44 (9) 1450-1458; DOI: https://doi.org/10.1124/dmd.116.069906

  3. Meyer, Jeffery

    1. Occupancy of Nociceptin/Orphanin FQ Peptide Receptors by the Antagonist LY2940094 in Rats and Healthy Human Subjects
      Eyas Raddad, Amy Chappell, Jeffery Meyer, Alan Wilson, Charles E. Ruegg, Johannes Tauscher, Michael A. Statnick, Vanessa Barth, Xin Zhang and Steven J. Verfaille
      Drug Metabolism and Disposition September 2016, 44 (9) 1536-1542; DOI: https://doi.org/10.1124/dmd.116.070359

  4. Mircioiu, Constantin

    1. Evaluation of Clopidogrel Conjugation Metabolism: PK Studies in Man and Mice of Clopidogrel Acyl Glucuronide
      Simona Nicoleta Savu, Luigi Silvestro, Mariana Surmeian, Lina Remis, Yuksel Rasit, Simona Rizea Savu and Constantin Mircioiu
      Drug Metabolism and Disposition September 2016, 44 (9) 1490-1497; DOI: https://doi.org/10.1124/dmd.116.071092

N

  1. Ni, Tong

    1. The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women
      Stefan Zajic, Stefaan Rossenu, David Hreniuk, Filippos Kesisoglou, Jacqueline McCrea, Fang Liu, Li Sun, Rose Witter, Don Gauthier, Roy Helmy, Darrick Joss, Tong Ni, Randall Stoltz, Julie Stone and S. Aubrey Stoch
      Drug Metabolism and Disposition September 2016, 44 (9) 1450-1458; DOI: https://doi.org/10.1124/dmd.116.069906

  2. Nunes, Irene

    1. The Complexities of Interpreting Reversible Elevated Serum Creatinine Levels in Drug Development: Does a Correlation with Inhibition of Renal Transporters Exist?
      Xiaoyan Chu, Kelly Bleasby, Grace Hoyee Chan, Irene Nunes and Raymond Evers
      Drug Metabolism and Disposition September 2016, 44 (9) 1498-1509; DOI: https://doi.org/10.1124/dmd.115.067694

P

  1. Pang, K. Sandy

    1. Functional Integrity of the Chimeric (Humanized) Mouse Liver: Enzyme Zonation, Physiologic Spaces, and Hepatic Enzymes and Transporters
      Edwin C. Y. Chow, Jason Z. Y. Wang, Holly P. Quach, Hui Tang, David C. Evans, Albert P. Li, Jose Silva and K. Sandy Pang
      Drug Metabolism and Disposition September 2016, 44 (9) 1524-1535; DOI: https://doi.org/10.1124/dmd.116.070060

  2. Pei, Zhonghua

    1. Open Access
      Chemical Structure and Concentration of Intratumor Catabolites Determine Efficacy of Antibody Drug Conjugates
      Donglu Zhang, Shang-Fan Yu, Yong Ma, Keyang Xu, Peter S. Dragovich, Thomas H. Pillow, Luna Liu, Geoffrey Del Rosario, Jintang He, Zhonghua Pei, Jack D. Sadowsky, Hans K. Erickson, Cornelis E. C. A. Hop and S. Cyrus Khojasteh
      Drug Metabolism and Disposition September 2016, 44 (9) 1517-1523; DOI: https://doi.org/10.1124/dmd.116.070631

  3. Pillow, Thomas H.

    1. Open Access
      Chemical Structure and Concentration of Intratumor Catabolites Determine Efficacy of Antibody Drug Conjugates
      Donglu Zhang, Shang-Fan Yu, Yong Ma, Keyang Xu, Peter S. Dragovich, Thomas H. Pillow, Luna Liu, Geoffrey Del Rosario, Jintang He, Zhonghua Pei, Jack D. Sadowsky, Hans K. Erickson, Cornelis E. C. A. Hop and S. Cyrus Khojasteh
      Drug Metabolism and Disposition September 2016, 44 (9) 1517-1523; DOI: https://doi.org/10.1124/dmd.116.070631

Q

  1. Quach, Holly P.

    1. Functional Integrity of the Chimeric (Humanized) Mouse Liver: Enzyme Zonation, Physiologic Spaces, and Hepatic Enzymes and Transporters
      Edwin C. Y. Chow, Jason Z. Y. Wang, Holly P. Quach, Hui Tang, David C. Evans, Albert P. Li, Jose Silva and K. Sandy Pang
      Drug Metabolism and Disposition September 2016, 44 (9) 1524-1535; DOI: https://doi.org/10.1124/dmd.116.070060

R

  1. Raddad, Eyas

    1. Occupancy of Nociceptin/Orphanin FQ Peptide Receptors by the Antagonist LY2940094 in Rats and Healthy Human Subjects
      Eyas Raddad, Amy Chappell, Jeffery Meyer, Alan Wilson, Charles E. Ruegg, Johannes Tauscher, Michael A. Statnick, Vanessa Barth, Xin Zhang and Steven J. Verfaille
      Drug Metabolism and Disposition September 2016, 44 (9) 1536-1542; DOI: https://doi.org/10.1124/dmd.116.070359

  2. Rasit, Yuksel

    1. Evaluation of Clopidogrel Conjugation Metabolism: PK Studies in Man and Mice of Clopidogrel Acyl Glucuronide
      Simona Nicoleta Savu, Luigi Silvestro, Mariana Surmeian, Lina Remis, Yuksel Rasit, Simona Rizea Savu and Constantin Mircioiu
      Drug Metabolism and Disposition September 2016, 44 (9) 1490-1497; DOI: https://doi.org/10.1124/dmd.116.071092

  3. Remis, Lina

    1. Evaluation of Clopidogrel Conjugation Metabolism: PK Studies in Man and Mice of Clopidogrel Acyl Glucuronide
      Simona Nicoleta Savu, Luigi Silvestro, Mariana Surmeian, Lina Remis, Yuksel Rasit, Simona Rizea Savu and Constantin Mircioiu
      Drug Metabolism and Disposition September 2016, 44 (9) 1490-1497; DOI: https://doi.org/10.1124/dmd.116.071092

  4. Rossenu, Stefaan

    1. The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women
      Stefan Zajic, Stefaan Rossenu, David Hreniuk, Filippos Kesisoglou, Jacqueline McCrea, Fang Liu, Li Sun, Rose Witter, Don Gauthier, Roy Helmy, Darrick Joss, Tong Ni, Randall Stoltz, Julie Stone and S. Aubrey Stoch
      Drug Metabolism and Disposition September 2016, 44 (9) 1450-1458; DOI: https://doi.org/10.1124/dmd.116.069906

  5. Ruegg, Charles E.

    1. Occupancy of Nociceptin/Orphanin FQ Peptide Receptors by the Antagonist LY2940094 in Rats and Healthy Human Subjects
      Eyas Raddad, Amy Chappell, Jeffery Meyer, Alan Wilson, Charles E. Ruegg, Johannes Tauscher, Michael A. Statnick, Vanessa Barth, Xin Zhang and Steven J. Verfaille
      Drug Metabolism and Disposition September 2016, 44 (9) 1536-1542; DOI: https://doi.org/10.1124/dmd.116.070359

S

  1. Sadowsky, Jack D.

    1. Open Access
      Chemical Structure and Concentration of Intratumor Catabolites Determine Efficacy of Antibody Drug Conjugates
      Donglu Zhang, Shang-Fan Yu, Yong Ma, Keyang Xu, Peter S. Dragovich, Thomas H. Pillow, Luna Liu, Geoffrey Del Rosario, Jintang He, Zhonghua Pei, Jack D. Sadowsky, Hans K. Erickson, Cornelis E. C. A. Hop and S. Cyrus Khojasteh
      Drug Metabolism and Disposition September 2016, 44 (9) 1517-1523; DOI: https://doi.org/10.1124/dmd.116.070631

  2. Savu, Simona Nicoleta

    1. Evaluation of Clopidogrel Conjugation Metabolism: PK Studies in Man and Mice of Clopidogrel Acyl Glucuronide
      Simona Nicoleta Savu, Luigi Silvestro, Mariana Surmeian, Lina Remis, Yuksel Rasit, Simona Rizea Savu and Constantin Mircioiu
      Drug Metabolism and Disposition September 2016, 44 (9) 1490-1497; DOI: https://doi.org/10.1124/dmd.116.071092

  3. Savu, Simona Rizea

    1. Evaluation of Clopidogrel Conjugation Metabolism: PK Studies in Man and Mice of Clopidogrel Acyl Glucuronide
      Simona Nicoleta Savu, Luigi Silvestro, Mariana Surmeian, Lina Remis, Yuksel Rasit, Simona Rizea Savu and Constantin Mircioiu
      Drug Metabolism and Disposition September 2016, 44 (9) 1490-1497; DOI: https://doi.org/10.1124/dmd.116.071092

  4. Silva, Jose

    1. Functional Integrity of the Chimeric (Humanized) Mouse Liver: Enzyme Zonation, Physiologic Spaces, and Hepatic Enzymes and Transporters
      Edwin C. Y. Chow, Jason Z. Y. Wang, Holly P. Quach, Hui Tang, David C. Evans, Albert P. Li, Jose Silva and K. Sandy Pang
      Drug Metabolism and Disposition September 2016, 44 (9) 1524-1535; DOI: https://doi.org/10.1124/dmd.116.070060

  5. Silvestro, Luigi

    1. Evaluation of Clopidogrel Conjugation Metabolism: PK Studies in Man and Mice of Clopidogrel Acyl Glucuronide
      Simona Nicoleta Savu, Luigi Silvestro, Mariana Surmeian, Lina Remis, Yuksel Rasit, Simona Rizea Savu and Constantin Mircioiu
      Drug Metabolism and Disposition September 2016, 44 (9) 1490-1497; DOI: https://doi.org/10.1124/dmd.116.071092

  6. Statnick, Michael A.

    1. Occupancy of Nociceptin/Orphanin FQ Peptide Receptors by the Antagonist LY2940094 in Rats and Healthy Human Subjects
      Eyas Raddad, Amy Chappell, Jeffery Meyer, Alan Wilson, Charles E. Ruegg, Johannes Tauscher, Michael A. Statnick, Vanessa Barth, Xin Zhang and Steven J. Verfaille
      Drug Metabolism and Disposition September 2016, 44 (9) 1536-1542; DOI: https://doi.org/10.1124/dmd.116.070359

  7. Stoch, S. Aubrey

    1. The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women
      Stefan Zajic, Stefaan Rossenu, David Hreniuk, Filippos Kesisoglou, Jacqueline McCrea, Fang Liu, Li Sun, Rose Witter, Don Gauthier, Roy Helmy, Darrick Joss, Tong Ni, Randall Stoltz, Julie Stone and S. Aubrey Stoch
      Drug Metabolism and Disposition September 2016, 44 (9) 1450-1458; DOI: https://doi.org/10.1124/dmd.116.069906

  8. Stoltz, Randall

    1. The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women
      Stefan Zajic, Stefaan Rossenu, David Hreniuk, Filippos Kesisoglou, Jacqueline McCrea, Fang Liu, Li Sun, Rose Witter, Don Gauthier, Roy Helmy, Darrick Joss, Tong Ni, Randall Stoltz, Julie Stone and S. Aubrey Stoch
      Drug Metabolism and Disposition September 2016, 44 (9) 1450-1458; DOI: https://doi.org/10.1124/dmd.116.069906

  9. Stone, Julie

    1. The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women
      Stefan Zajic, Stefaan Rossenu, David Hreniuk, Filippos Kesisoglou, Jacqueline McCrea, Fang Liu, Li Sun, Rose Witter, Don Gauthier, Roy Helmy, Darrick Joss, Tong Ni, Randall Stoltz, Julie Stone and S. Aubrey Stoch
      Drug Metabolism and Disposition September 2016, 44 (9) 1450-1458; DOI: https://doi.org/10.1124/dmd.116.069906

  10. Sun, Li

    1. The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women
      Stefan Zajic, Stefaan Rossenu, David Hreniuk, Filippos Kesisoglou, Jacqueline McCrea, Fang Liu, Li Sun, Rose Witter, Don Gauthier, Roy Helmy, Darrick Joss, Tong Ni, Randall Stoltz, Julie Stone and S. Aubrey Stoch
      Drug Metabolism and Disposition September 2016, 44 (9) 1450-1458; DOI: https://doi.org/10.1124/dmd.116.069906

  11. Surmeian, Mariana

    1. Evaluation of Clopidogrel Conjugation Metabolism: PK Studies in Man and Mice of Clopidogrel Acyl Glucuronide
      Simona Nicoleta Savu, Luigi Silvestro, Mariana Surmeian, Lina Remis, Yuksel Rasit, Simona Rizea Savu and Constantin Mircioiu
      Drug Metabolism and Disposition September 2016, 44 (9) 1490-1497; DOI: https://doi.org/10.1124/dmd.116.071092

T

  1. Tang, Hui

    1. Functional Integrity of the Chimeric (Humanized) Mouse Liver: Enzyme Zonation, Physiologic Spaces, and Hepatic Enzymes and Transporters
      Edwin C. Y. Chow, Jason Z. Y. Wang, Holly P. Quach, Hui Tang, David C. Evans, Albert P. Li, Jose Silva and K. Sandy Pang
      Drug Metabolism and Disposition September 2016, 44 (9) 1524-1535; DOI: https://doi.org/10.1124/dmd.116.070060

  2. Tauscher, Johannes

    1. Occupancy of Nociceptin/Orphanin FQ Peptide Receptors by the Antagonist LY2940094 in Rats and Healthy Human Subjects
      Eyas Raddad, Amy Chappell, Jeffery Meyer, Alan Wilson, Charles E. Ruegg, Johannes Tauscher, Michael A. Statnick, Vanessa Barth, Xin Zhang and Steven J. Verfaille
      Drug Metabolism and Disposition September 2016, 44 (9) 1536-1542; DOI: https://doi.org/10.1124/dmd.116.070359

V

  1. Verfaille, Steven J.

    1. Occupancy of Nociceptin/Orphanin FQ Peptide Receptors by the Antagonist LY2940094 in Rats and Healthy Human Subjects
      Eyas Raddad, Amy Chappell, Jeffery Meyer, Alan Wilson, Charles E. Ruegg, Johannes Tauscher, Michael A. Statnick, Vanessa Barth, Xin Zhang and Steven J. Verfaille
      Drug Metabolism and Disposition September 2016, 44 (9) 1536-1542; DOI: https://doi.org/10.1124/dmd.116.070359

W

  1. Wang, Hongbing

    1. Contextualizing Hepatocyte Functionality of Cryopreserved HepaRG Cell Cultures
      Jonathan P. Jackson, Linhou Li, Erica D. Chamberlain, Hongbing Wang and Stephen S. Ferguson
      Drug Metabolism and Disposition September 2016, 44 (9) 1463-1479; DOI: https://doi.org/10.1124/dmd.116.069831

  2. Wang, Huijuan

    1. Identification of Genetic Polymorphisms of CYP2W1 in the Three Main Chinese Ethnicities: Han, Tibetan, and Uighur
      Yanwei Li, Xing Kang, Ge Yang, Penggao Dai, Chao Chen and Huijuan Wang
      Drug Metabolism and Disposition September 2016, 44 (9) 1510-1515; DOI: https://doi.org/10.1124/dmd.115.069153

  3. Wang, Jason Z. Y.

    1. Functional Integrity of the Chimeric (Humanized) Mouse Liver: Enzyme Zonation, Physiologic Spaces, and Hepatic Enzymes and Transporters
      Edwin C. Y. Chow, Jason Z. Y. Wang, Holly P. Quach, Hui Tang, David C. Evans, Albert P. Li, Jose Silva and K. Sandy Pang
      Drug Metabolism and Disposition September 2016, 44 (9) 1524-1535; DOI: https://doi.org/10.1124/dmd.116.070060

  4. Wang, Shuai

    1. Arylsulfatase B Mediates the Sulfonation-Transport Interplay in Human Embryonic Kidney 293 Cells Overexpressing Sulfotransferase 1A3
      Mengjing Zhao, Shuai Wang, Feng Li, Dong Dong and Baojian Wu
      Drug Metabolism and Disposition September 2016, 44 (9) 1441-1449; DOI: https://doi.org/10.1124/dmd.116.070938

  5. Wilson, Alan

    1. Occupancy of Nociceptin/Orphanin FQ Peptide Receptors by the Antagonist LY2940094 in Rats and Healthy Human Subjects
      Eyas Raddad, Amy Chappell, Jeffery Meyer, Alan Wilson, Charles E. Ruegg, Johannes Tauscher, Michael A. Statnick, Vanessa Barth, Xin Zhang and Steven J. Verfaille
      Drug Metabolism and Disposition September 2016, 44 (9) 1536-1542; DOI: https://doi.org/10.1124/dmd.116.070359

  6. Witter, Rose

    1. The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women
      Stefan Zajic, Stefaan Rossenu, David Hreniuk, Filippos Kesisoglou, Jacqueline McCrea, Fang Liu, Li Sun, Rose Witter, Don Gauthier, Roy Helmy, Darrick Joss, Tong Ni, Randall Stoltz, Julie Stone and S. Aubrey Stoch
      Drug Metabolism and Disposition September 2016, 44 (9) 1450-1458; DOI: https://doi.org/10.1124/dmd.116.069906

  7. Wu, Baojian

    1. Arylsulfatase B Mediates the Sulfonation-Transport Interplay in Human Embryonic Kidney 293 Cells Overexpressing Sulfotransferase 1A3
      Mengjing Zhao, Shuai Wang, Feng Li, Dong Dong and Baojian Wu
      Drug Metabolism and Disposition September 2016, 44 (9) 1441-1449; DOI: https://doi.org/10.1124/dmd.116.070938

X

  1. Xu, Keyang

    1. Open Access
      Chemical Structure and Concentration of Intratumor Catabolites Determine Efficacy of Antibody Drug Conjugates
      Donglu Zhang, Shang-Fan Yu, Yong Ma, Keyang Xu, Peter S. Dragovich, Thomas H. Pillow, Luna Liu, Geoffrey Del Rosario, Jintang He, Zhonghua Pei, Jack D. Sadowsky, Hans K. Erickson, Cornelis E. C. A. Hop and S. Cyrus Khojasteh
      Drug Metabolism and Disposition September 2016, 44 (9) 1517-1523; DOI: https://doi.org/10.1124/dmd.116.070631

Y

  1. Yang, Ge

    1. Identification of Genetic Polymorphisms of CYP2W1 in the Three Main Chinese Ethnicities: Han, Tibetan, and Uighur
      Yanwei Li, Xing Kang, Ge Yang, Penggao Dai, Chao Chen and Huijuan Wang
      Drug Metabolism and Disposition September 2016, 44 (9) 1510-1515; DOI: https://doi.org/10.1124/dmd.115.069153

  2. Yu, Shang-Fan

    1. Open Access
      Chemical Structure and Concentration of Intratumor Catabolites Determine Efficacy of Antibody Drug Conjugates
      Donglu Zhang, Shang-Fan Yu, Yong Ma, Keyang Xu, Peter S. Dragovich, Thomas H. Pillow, Luna Liu, Geoffrey Del Rosario, Jintang He, Zhonghua Pei, Jack D. Sadowsky, Hans K. Erickson, Cornelis E. C. A. Hop and S. Cyrus Khojasteh
      Drug Metabolism and Disposition September 2016, 44 (9) 1517-1523; DOI: https://doi.org/10.1124/dmd.116.070631

Z

  1. Zajic, Stefan

    1. The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women
      Stefan Zajic, Stefaan Rossenu, David Hreniuk, Filippos Kesisoglou, Jacqueline McCrea, Fang Liu, Li Sun, Rose Witter, Don Gauthier, Roy Helmy, Darrick Joss, Tong Ni, Randall Stoltz, Julie Stone and S. Aubrey Stoch
      Drug Metabolism and Disposition September 2016, 44 (9) 1450-1458; DOI: https://doi.org/10.1124/dmd.116.069906

  2. Zhang, Donglu

    1. Open Access
      Chemical Structure and Concentration of Intratumor Catabolites Determine Efficacy of Antibody Drug Conjugates
      Donglu Zhang, Shang-Fan Yu, Yong Ma, Keyang Xu, Peter S. Dragovich, Thomas H. Pillow, Luna Liu, Geoffrey Del Rosario, Jintang He, Zhonghua Pei, Jack D. Sadowsky, Hans K. Erickson, Cornelis E. C. A. Hop and S. Cyrus Khojasteh
      Drug Metabolism and Disposition September 2016, 44 (9) 1517-1523; DOI: https://doi.org/10.1124/dmd.116.070631

  3. Zhang, Xin

    1. Occupancy of Nociceptin/Orphanin FQ Peptide Receptors by the Antagonist LY2940094 in Rats and Healthy Human Subjects
      Eyas Raddad, Amy Chappell, Jeffery Meyer, Alan Wilson, Charles E. Ruegg, Johannes Tauscher, Michael A. Statnick, Vanessa Barth, Xin Zhang and Steven J. Verfaille
      Drug Metabolism and Disposition September 2016, 44 (9) 1536-1542; DOI: https://doi.org/10.1124/dmd.116.070359

  4. Zhao, Mengjing

    1. Arylsulfatase B Mediates the Sulfonation-Transport Interplay in Human Embryonic Kidney 293 Cells Overexpressing Sulfotransferase 1A3
      Mengjing Zhao, Shuai Wang, Feng Li, Dong Dong and Baojian Wu
      Drug Metabolism and Disposition September 2016, 44 (9) 1441-1449; DOI: https://doi.org/10.1124/dmd.116.070938
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