Research ArticleArticle
Evaluation of Clopidogrel Conjugation Metabolism: PK Studies in Man and Mice of Clopidogrel Acyl Glucuronide
Simona Nicoleta Savu, Luigi Silvestro, Mariana Surmeian, Lina Remis, Yuksel Rasit, Simona Rizea Savu and Constantin Mircioiu
Drug Metabolism and Disposition September 2016, 44 (9) 1490-1497; DOI: https://doi.org/10.1124/dmd.116.071092
Simona Nicoleta Savu
Department of Biopharmacy, Faculty of Pharmacy, University of Medicine and Pharmacy “Carol Davila,” Bucharest, Romania (S.N.S., C.M.); 3S-Pharmacological Consultation and Research GmbH, Harpstedt, Germany (S.N.S, L.S., S.R.S.); Pharma Serv International SRL, Bucharest, Romania (M.S.); Clinical Hospital of the Ministry of Health of the Moldavian Republic, Chisinau, The Moldavian Republic (L.R.); Pharmacology Department, National Institute for Chemical Pharmaceutical Research and Development (ICCF), Bucharest, Romania (Y.R.)
Luigi Silvestro
Department of Biopharmacy, Faculty of Pharmacy, University of Medicine and Pharmacy “Carol Davila,” Bucharest, Romania (S.N.S., C.M.); 3S-Pharmacological Consultation and Research GmbH, Harpstedt, Germany (S.N.S, L.S., S.R.S.); Pharma Serv International SRL, Bucharest, Romania (M.S.); Clinical Hospital of the Ministry of Health of the Moldavian Republic, Chisinau, The Moldavian Republic (L.R.); Pharmacology Department, National Institute for Chemical Pharmaceutical Research and Development (ICCF), Bucharest, Romania (Y.R.)
Mariana Surmeian
Department of Biopharmacy, Faculty of Pharmacy, University of Medicine and Pharmacy “Carol Davila,” Bucharest, Romania (S.N.S., C.M.); 3S-Pharmacological Consultation and Research GmbH, Harpstedt, Germany (S.N.S, L.S., S.R.S.); Pharma Serv International SRL, Bucharest, Romania (M.S.); Clinical Hospital of the Ministry of Health of the Moldavian Republic, Chisinau, The Moldavian Republic (L.R.); Pharmacology Department, National Institute for Chemical Pharmaceutical Research and Development (ICCF), Bucharest, Romania (Y.R.)
Lina Remis
Department of Biopharmacy, Faculty of Pharmacy, University of Medicine and Pharmacy “Carol Davila,” Bucharest, Romania (S.N.S., C.M.); 3S-Pharmacological Consultation and Research GmbH, Harpstedt, Germany (S.N.S, L.S., S.R.S.); Pharma Serv International SRL, Bucharest, Romania (M.S.); Clinical Hospital of the Ministry of Health of the Moldavian Republic, Chisinau, The Moldavian Republic (L.R.); Pharmacology Department, National Institute for Chemical Pharmaceutical Research and Development (ICCF), Bucharest, Romania (Y.R.)
Yuksel Rasit
Department of Biopharmacy, Faculty of Pharmacy, University of Medicine and Pharmacy “Carol Davila,” Bucharest, Romania (S.N.S., C.M.); 3S-Pharmacological Consultation and Research GmbH, Harpstedt, Germany (S.N.S, L.S., S.R.S.); Pharma Serv International SRL, Bucharest, Romania (M.S.); Clinical Hospital of the Ministry of Health of the Moldavian Republic, Chisinau, The Moldavian Republic (L.R.); Pharmacology Department, National Institute for Chemical Pharmaceutical Research and Development (ICCF), Bucharest, Romania (Y.R.)
Simona Rizea Savu
Department of Biopharmacy, Faculty of Pharmacy, University of Medicine and Pharmacy “Carol Davila,” Bucharest, Romania (S.N.S., C.M.); 3S-Pharmacological Consultation and Research GmbH, Harpstedt, Germany (S.N.S, L.S., S.R.S.); Pharma Serv International SRL, Bucharest, Romania (M.S.); Clinical Hospital of the Ministry of Health of the Moldavian Republic, Chisinau, The Moldavian Republic (L.R.); Pharmacology Department, National Institute for Chemical Pharmaceutical Research and Development (ICCF), Bucharest, Romania (Y.R.)
Constantin Mircioiu
Department of Biopharmacy, Faculty of Pharmacy, University of Medicine and Pharmacy “Carol Davila,” Bucharest, Romania (S.N.S., C.M.); 3S-Pharmacological Consultation and Research GmbH, Harpstedt, Germany (S.N.S, L.S., S.R.S.); Pharma Serv International SRL, Bucharest, Romania (M.S.); Clinical Hospital of the Ministry of Health of the Moldavian Republic, Chisinau, The Moldavian Republic (L.R.); Pharmacology Department, National Institute for Chemical Pharmaceutical Research and Development (ICCF), Bucharest, Romania (Y.R.)
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Research ArticleArticle
PK of Clopidogrel Acyl Glucuronide in Man and Mice
Simona Nicoleta Savu, Luigi Silvestro, Mariana Surmeian, Lina Remis, Yuksel Rasit, Simona Rizea Savu and Constantin Mircioiu
Drug Metabolism and Disposition September 1, 2016, 44 (9) 1490-1497; DOI: https://doi.org/10.1124/dmd.116.071092
Research ArticleArticle
PK of Clopidogrel Acyl Glucuronide in Man and Mice
Simona Nicoleta Savu, Luigi Silvestro, Mariana Surmeian, Lina Remis, Yuksel Rasit, Simona Rizea Savu and Constantin Mircioiu
Drug Metabolism and Disposition September 1, 2016, 44 (9) 1490-1497; DOI: https://doi.org/10.1124/dmd.116.071092
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