Index by author
January 01, 2017; Volume 45,Issue 1
A
Andersson, Tommy B.
- You have accessManaging the Risk of CYP3A Induction in Drug Development: A Strategic ApproachBarry C. Jones, Helen Rollison, Susanne Johansson, Kajsa P. Kanebratt, Craig Lambert, Karthick Vishwanathan and Tommy B. AnderssonDrug Metabolism and Disposition January 2017, 45 (1) 35-41; DOI: https://doi.org/10.1124/dmd.116.072025
B
Banfield, Christopher
- You have accessClearance Prediction of Targeted Covalent Inhibitors by In Vitro-In Vivo Extrapolation of Hepatic and Extrahepatic Clearance MechanismsLouis Leung, Xin Yang, Timothy J. Strelevitz, Justin Montgomery, Matthew F. Brown, Michael A. Zientek, Christopher Banfield, Adam M. Gilbert, Atli Thorarensen and Martin E. DowtyDrug Metabolism and Disposition January 2017, 45 (1) 1-7; DOI: https://doi.org/10.1124/dmd.116.072983
Brown, Matthew F.
- You have accessClearance Prediction of Targeted Covalent Inhibitors by In Vitro-In Vivo Extrapolation of Hepatic and Extrahepatic Clearance MechanismsLouis Leung, Xin Yang, Timothy J. Strelevitz, Justin Montgomery, Matthew F. Brown, Michael A. Zientek, Christopher Banfield, Adam M. Gilbert, Atli Thorarensen and Martin E. DowtyDrug Metabolism and Disposition January 2017, 45 (1) 1-7; DOI: https://doi.org/10.1124/dmd.116.072983
Bundgaard, Christoffer
- You have accessLack of Exposure in a First-in-Man Study Due to Aldehyde Oxidase Metabolism: Investigated by Use of 14C-microdose, Humanized Mice, Monkey Pharmacokinetics, and In Vitro MethodsKlaus Gjervig Jensen, Anne-Marie Jacobsen, Christoffer Bundgaard, Dorrit Østergaard Nilausen, Zia Thale, Gamini Chandrasena and Martin JørgensenDrug Metabolism and Disposition January 2017, 45 (1) 68-75; DOI: https://doi.org/10.1124/dmd.116.072793
C
Chamuleau, Robert A. F. M.
- You have accessStable Overexpression of the Constitutive Androstane Receptor Reduces the Requirement for Culture with Dimethyl Sulfoxide for High Drug Metabolism in HepaRG CellsVincent A. van der Mark, D. Rudi de Waart, Valery Shevchenko, Ronald P.J. Oude Elferink, Robert A. F. M. Chamuleau and Ruurdtje HoekstraDrug Metabolism and Disposition January 2017, 45 (1) 56-67; DOI: https://doi.org/10.1124/dmd.116.072603
Chandrasekhar, Jayaraman
- You have accessInteraction of 2,4-Diaminopyrimidine–Containing Drugs Including Fedratinib and Trimethoprim with Thiamine TransportersMarilyn M. Giacomini, Jia Hao, Xiaomin Liang, Jayaraman Chandrasekhar, Jolyn Twelves, J. Andrew Whitney, Eve-Irene Lepist and Adrian S. RayDrug Metabolism and Disposition January 2017, 45 (1) 76-85; DOI: https://doi.org/10.1124/dmd.116.073338
Chandrasena, Gamini
- You have accessLack of Exposure in a First-in-Man Study Due to Aldehyde Oxidase Metabolism: Investigated by Use of 14C-microdose, Humanized Mice, Monkey Pharmacokinetics, and In Vitro MethodsKlaus Gjervig Jensen, Anne-Marie Jacobsen, Christoffer Bundgaard, Dorrit Østergaard Nilausen, Zia Thale, Gamini Chandrasena and Martin JørgensenDrug Metabolism and Disposition January 2017, 45 (1) 68-75; DOI: https://doi.org/10.1124/dmd.116.072793
Chen, Liangfu
- You have accessInhibition of Intestinal OATP2B1 by the Calcium Receptor Antagonist Ronacaleret Results in a Significant Drug-Drug Interaction by Causing a 2-Fold Decrease in Exposure of RosuvastatinMarta Johnson, Dipal Patel, Christopher Matheny, May Ho, Liangfu Chen and Harma EllensDrug Metabolism and Disposition January 2017, 45 (1) 27-34; DOI: https://doi.org/10.1124/dmd.116.072397
D
Dowty, Martin E.
- You have accessClearance Prediction of Targeted Covalent Inhibitors by In Vitro-In Vivo Extrapolation of Hepatic and Extrahepatic Clearance MechanismsLouis Leung, Xin Yang, Timothy J. Strelevitz, Justin Montgomery, Matthew F. Brown, Michael A. Zientek, Christopher Banfield, Adam M. Gilbert, Atli Thorarensen and Martin E. DowtyDrug Metabolism and Disposition January 2017, 45 (1) 1-7; DOI: https://doi.org/10.1124/dmd.116.072983
E
Elferink, Ronald P.J. Oude
- You have accessStable Overexpression of the Constitutive Androstane Receptor Reduces the Requirement for Culture with Dimethyl Sulfoxide for High Drug Metabolism in HepaRG CellsVincent A. van der Mark, D. Rudi de Waart, Valery Shevchenko, Ronald P.J. Oude Elferink, Robert A. F. M. Chamuleau and Ruurdtje HoekstraDrug Metabolism and Disposition January 2017, 45 (1) 56-67; DOI: https://doi.org/10.1124/dmd.116.072603
Ellens, Harma
- You have accessInhibition of Intestinal OATP2B1 by the Calcium Receptor Antagonist Ronacaleret Results in a Significant Drug-Drug Interaction by Causing a 2-Fold Decrease in Exposure of RosuvastatinMarta Johnson, Dipal Patel, Christopher Matheny, May Ho, Liangfu Chen and Harma EllensDrug Metabolism and Disposition January 2017, 45 (1) 27-34; DOI: https://doi.org/10.1124/dmd.116.072397
Emoto, Chie
- You have accessDevelopmental Changes in Hepatic Organic Cation Transporter OCT1 Protein Expression from Neonates to ChildrenDavid Hahn, Chie Emoto, Alexander A. Vinks and Tsuyoshi FukudaDrug Metabolism and Disposition January 2017, 45 (1) 23-26; DOI: https://doi.org/10.1124/dmd.116.072256
F
Foster, David J. R.
- You have accessIntracellular CD3+ T Lymphocyte Teriflunomide Concentration Is Poorly Correlated with and Has Greater Variability Than Unbound Plasma Teriflunomide ConcentrationAshley M. Hopkins, Mahin Moghaddami, David J. R. Foster, Susanna M. Proudman, Richard N. Upton and Michael D. WieseDrug Metabolism and Disposition January 2017, 45 (1) 8-16; DOI: https://doi.org/10.1124/dmd.116.071985
Fukuda, Tsuyoshi
- You have accessDevelopmental Changes in Hepatic Organic Cation Transporter OCT1 Protein Expression from Neonates to ChildrenDavid Hahn, Chie Emoto, Alexander A. Vinks and Tsuyoshi FukudaDrug Metabolism and Disposition January 2017, 45 (1) 23-26; DOI: https://doi.org/10.1124/dmd.116.072256
G
Giacomini, Marilyn M.
- You have accessInteraction of 2,4-Diaminopyrimidine–Containing Drugs Including Fedratinib and Trimethoprim with Thiamine TransportersMarilyn M. Giacomini, Jia Hao, Xiaomin Liang, Jayaraman Chandrasekhar, Jolyn Twelves, J. Andrew Whitney, Eve-Irene Lepist and Adrian S. RayDrug Metabolism and Disposition January 2017, 45 (1) 76-85; DOI: https://doi.org/10.1124/dmd.116.073338
Gilbert, Adam M.
- You have accessClearance Prediction of Targeted Covalent Inhibitors by In Vitro-In Vivo Extrapolation of Hepatic and Extrahepatic Clearance MechanismsLouis Leung, Xin Yang, Timothy J. Strelevitz, Justin Montgomery, Matthew F. Brown, Michael A. Zientek, Christopher Banfield, Adam M. Gilbert, Atli Thorarensen and Martin E. DowtyDrug Metabolism and Disposition January 2017, 45 (1) 1-7; DOI: https://doi.org/10.1124/dmd.116.072983
H
Hahn, David
- You have accessDevelopmental Changes in Hepatic Organic Cation Transporter OCT1 Protein Expression from Neonates to ChildrenDavid Hahn, Chie Emoto, Alexander A. Vinks and Tsuyoshi FukudaDrug Metabolism and Disposition January 2017, 45 (1) 23-26; DOI: https://doi.org/10.1124/dmd.116.072256
Hao, Jia
- You have accessInteraction of 2,4-Diaminopyrimidine–Containing Drugs Including Fedratinib and Trimethoprim with Thiamine TransportersMarilyn M. Giacomini, Jia Hao, Xiaomin Liang, Jayaraman Chandrasekhar, Jolyn Twelves, J. Andrew Whitney, Eve-Irene Lepist and Adrian S. RayDrug Metabolism and Disposition January 2017, 45 (1) 76-85; DOI: https://doi.org/10.1124/dmd.116.073338
He, Huadong
- You have accessHistone H3 Lysine 4 Trimethylation, Lysine 27 Trimethylation, and Lysine 27 Acetylation Contribute to the Transcriptional Repression of Solute Carrier Family 47 Member 2 in Renal Cell CarcinomaQinqin Yu, Yanqing Liu, Xiaoli Zheng, Qianying Zhu, Zhuowei Shen, Hua Wang, Huadong He, Nengming Lin, Huidi Jiang, Lushan Yu and Su ZengDrug Metabolism and Disposition January 2017, 45 (1) 109-117; DOI: https://doi.org/10.1124/dmd.116.073734
Henderson, Colin J.
- Open AccessApplication of Mice Humanized for CYP2D6 to the Study of Tamoxifen Metabolism and Drug–Drug Interaction with AntidepressantsA. Kenneth MacLeod, Lesley A. McLaughlin, Colin J. Henderson and C. Roland WolfDrug Metabolism and Disposition January 2017, 45 (1) 17-22; DOI: https://doi.org/10.1124/dmd.116.073437
Ho, May
- You have accessInhibition of Intestinal OATP2B1 by the Calcium Receptor Antagonist Ronacaleret Results in a Significant Drug-Drug Interaction by Causing a 2-Fold Decrease in Exposure of RosuvastatinMarta Johnson, Dipal Patel, Christopher Matheny, May Ho, Liangfu Chen and Harma EllensDrug Metabolism and Disposition January 2017, 45 (1) 27-34; DOI: https://doi.org/10.1124/dmd.116.072397
Hoekstra, Ruurdtje
- You have accessStable Overexpression of the Constitutive Androstane Receptor Reduces the Requirement for Culture with Dimethyl Sulfoxide for High Drug Metabolism in HepaRG CellsVincent A. van der Mark, D. Rudi de Waart, Valery Shevchenko, Ronald P.J. Oude Elferink, Robert A. F. M. Chamuleau and Ruurdtje HoekstraDrug Metabolism and Disposition January 2017, 45 (1) 56-67; DOI: https://doi.org/10.1124/dmd.116.072603
Hopkins, Ashley M.
- You have accessIntracellular CD3+ T Lymphocyte Teriflunomide Concentration Is Poorly Correlated with and Has Greater Variability Than Unbound Plasma Teriflunomide ConcentrationAshley M. Hopkins, Mahin Moghaddami, David J. R. Foster, Susanna M. Proudman, Richard N. Upton and Michael D. WieseDrug Metabolism and Disposition January 2017, 45 (1) 8-16; DOI: https://doi.org/10.1124/dmd.116.071985
J
Jacobsen, Anne-Marie
- You have accessLack of Exposure in a First-in-Man Study Due to Aldehyde Oxidase Metabolism: Investigated by Use of 14C-microdose, Humanized Mice, Monkey Pharmacokinetics, and In Vitro MethodsKlaus Gjervig Jensen, Anne-Marie Jacobsen, Christoffer Bundgaard, Dorrit Østergaard Nilausen, Zia Thale, Gamini Chandrasena and Martin JørgensenDrug Metabolism and Disposition January 2017, 45 (1) 68-75; DOI: https://doi.org/10.1124/dmd.116.072793
Jensen, Klaus Gjervig
- You have accessLack of Exposure in a First-in-Man Study Due to Aldehyde Oxidase Metabolism: Investigated by Use of 14C-microdose, Humanized Mice, Monkey Pharmacokinetics, and In Vitro MethodsKlaus Gjervig Jensen, Anne-Marie Jacobsen, Christoffer Bundgaard, Dorrit Østergaard Nilausen, Zia Thale, Gamini Chandrasena and Martin JørgensenDrug Metabolism and Disposition January 2017, 45 (1) 68-75; DOI: https://doi.org/10.1124/dmd.116.072793
Jeong, Hyunyoung
- You have accessTranscriptional Regulation of CYP2D6 ExpressionXian Pan, Miaoran Ning and Hyunyoung JeongDrug Metabolism and Disposition January 2017, 45 (1) 42-48; DOI: https://doi.org/10.1124/dmd.116.072249
Jiang, Huidi
- You have accessHistone H3 Lysine 4 Trimethylation, Lysine 27 Trimethylation, and Lysine 27 Acetylation Contribute to the Transcriptional Repression of Solute Carrier Family 47 Member 2 in Renal Cell CarcinomaQinqin Yu, Yanqing Liu, Xiaoli Zheng, Qianying Zhu, Zhuowei Shen, Hua Wang, Huadong He, Nengming Lin, Huidi Jiang, Lushan Yu and Su ZengDrug Metabolism and Disposition January 2017, 45 (1) 109-117; DOI: https://doi.org/10.1124/dmd.116.073734
Johansson, Susanne
- You have accessManaging the Risk of CYP3A Induction in Drug Development: A Strategic ApproachBarry C. Jones, Helen Rollison, Susanne Johansson, Kajsa P. Kanebratt, Craig Lambert, Karthick Vishwanathan and Tommy B. AnderssonDrug Metabolism and Disposition January 2017, 45 (1) 35-41; DOI: https://doi.org/10.1124/dmd.116.072025
Johnson, Marta
- You have accessInhibition of Intestinal OATP2B1 by the Calcium Receptor Antagonist Ronacaleret Results in a Significant Drug-Drug Interaction by Causing a 2-Fold Decrease in Exposure of RosuvastatinMarta Johnson, Dipal Patel, Christopher Matheny, May Ho, Liangfu Chen and Harma EllensDrug Metabolism and Disposition January 2017, 45 (1) 27-34; DOI: https://doi.org/10.1124/dmd.116.072397
Jones, Barry C.
- You have accessManaging the Risk of CYP3A Induction in Drug Development: A Strategic ApproachBarry C. Jones, Helen Rollison, Susanne Johansson, Kajsa P. Kanebratt, Craig Lambert, Karthick Vishwanathan and Tommy B. AnderssonDrug Metabolism and Disposition January 2017, 45 (1) 35-41; DOI: https://doi.org/10.1124/dmd.116.072025
Jørgensen, Martin
- You have accessLack of Exposure in a First-in-Man Study Due to Aldehyde Oxidase Metabolism: Investigated by Use of 14C-microdose, Humanized Mice, Monkey Pharmacokinetics, and In Vitro MethodsKlaus Gjervig Jensen, Anne-Marie Jacobsen, Christoffer Bundgaard, Dorrit Østergaard Nilausen, Zia Thale, Gamini Chandrasena and Martin JørgensenDrug Metabolism and Disposition January 2017, 45 (1) 68-75; DOI: https://doi.org/10.1124/dmd.116.072793
K
Kanebratt, Kajsa P.
- You have accessManaging the Risk of CYP3A Induction in Drug Development: A Strategic ApproachBarry C. Jones, Helen Rollison, Susanne Johansson, Kajsa P. Kanebratt, Craig Lambert, Karthick Vishwanathan and Tommy B. AnderssonDrug Metabolism and Disposition January 2017, 45 (1) 35-41; DOI: https://doi.org/10.1124/dmd.116.072025
L
Lambert, Craig
- You have accessManaging the Risk of CYP3A Induction in Drug Development: A Strategic ApproachBarry C. Jones, Helen Rollison, Susanne Johansson, Kajsa P. Kanebratt, Craig Lambert, Karthick Vishwanathan and Tommy B. AnderssonDrug Metabolism and Disposition January 2017, 45 (1) 35-41; DOI: https://doi.org/10.1124/dmd.116.072025
Lepist, Eve-Irene
- You have accessInteraction of 2,4-Diaminopyrimidine–Containing Drugs Including Fedratinib and Trimethoprim with Thiamine TransportersMarilyn M. Giacomini, Jia Hao, Xiaomin Liang, Jayaraman Chandrasekhar, Jolyn Twelves, J. Andrew Whitney, Eve-Irene Lepist and Adrian S. RayDrug Metabolism and Disposition January 2017, 45 (1) 76-85; DOI: https://doi.org/10.1124/dmd.116.073338
Leung, Louis
- You have accessClearance Prediction of Targeted Covalent Inhibitors by In Vitro-In Vivo Extrapolation of Hepatic and Extrahepatic Clearance MechanismsLouis Leung, Xin Yang, Timothy J. Strelevitz, Justin Montgomery, Matthew F. Brown, Michael A. Zientek, Christopher Banfield, Adam M. Gilbert, Atli Thorarensen and Martin E. DowtyDrug Metabolism and Disposition January 2017, 45 (1) 1-7; DOI: https://doi.org/10.1124/dmd.116.072983
Liang, Xiaomin
- You have accessInteraction of 2,4-Diaminopyrimidine–Containing Drugs Including Fedratinib and Trimethoprim with Thiamine TransportersMarilyn M. Giacomini, Jia Hao, Xiaomin Liang, Jayaraman Chandrasekhar, Jolyn Twelves, J. Andrew Whitney, Eve-Irene Lepist and Adrian S. RayDrug Metabolism and Disposition January 2017, 45 (1) 76-85; DOI: https://doi.org/10.1124/dmd.116.073338
Lim, Lee Yong
- You have accessCurcumin, Piperine, and Capsaicin: A Comparative Study of Spice-Mediated Inhibition of Human Cytochrome P450 Isozyme ActivitiesSuhaili Shamsi, Huong Tran, Renee Seok Jin Tan, Zee Jian Tan and Lee Yong LimDrug Metabolism and Disposition January 2017, 45 (1) 49-55; DOI: https://doi.org/10.1124/dmd.116.073213
Lin, Nengming
- You have accessHistone H3 Lysine 4 Trimethylation, Lysine 27 Trimethylation, and Lysine 27 Acetylation Contribute to the Transcriptional Repression of Solute Carrier Family 47 Member 2 in Renal Cell CarcinomaQinqin Yu, Yanqing Liu, Xiaoli Zheng, Qianying Zhu, Zhuowei Shen, Hua Wang, Huadong He, Nengming Lin, Huidi Jiang, Lushan Yu and Su ZengDrug Metabolism and Disposition January 2017, 45 (1) 109-117; DOI: https://doi.org/10.1124/dmd.116.073734
Liu, Yanqing
- You have accessHistone H3 Lysine 4 Trimethylation, Lysine 27 Trimethylation, and Lysine 27 Acetylation Contribute to the Transcriptional Repression of Solute Carrier Family 47 Member 2 in Renal Cell CarcinomaQinqin Yu, Yanqing Liu, Xiaoli Zheng, Qianying Zhu, Zhuowei Shen, Hua Wang, Huadong He, Nengming Lin, Huidi Jiang, Lushan Yu and Su ZengDrug Metabolism and Disposition January 2017, 45 (1) 109-117; DOI: https://doi.org/10.1124/dmd.116.073734
M
MacLeod, A. Kenneth
- Open AccessApplication of Mice Humanized for CYP2D6 to the Study of Tamoxifen Metabolism and Drug–Drug Interaction with AntidepressantsA. Kenneth MacLeod, Lesley A. McLaughlin, Colin J. Henderson and C. Roland WolfDrug Metabolism and Disposition January 2017, 45 (1) 17-22; DOI: https://doi.org/10.1124/dmd.116.073437
Matheny, Christopher
- You have accessInhibition of Intestinal OATP2B1 by the Calcium Receptor Antagonist Ronacaleret Results in a Significant Drug-Drug Interaction by Causing a 2-Fold Decrease in Exposure of RosuvastatinMarta Johnson, Dipal Patel, Christopher Matheny, May Ho, Liangfu Chen and Harma EllensDrug Metabolism and Disposition January 2017, 45 (1) 27-34; DOI: https://doi.org/10.1124/dmd.116.072397
McLaughlin, Lesley A.
- Open AccessApplication of Mice Humanized for CYP2D6 to the Study of Tamoxifen Metabolism and Drug–Drug Interaction with AntidepressantsA. Kenneth MacLeod, Lesley A. McLaughlin, Colin J. Henderson and C. Roland WolfDrug Metabolism and Disposition January 2017, 45 (1) 17-22; DOI: https://doi.org/10.1124/dmd.116.073437
Moghaddami, Mahin
- You have accessIntracellular CD3+ T Lymphocyte Teriflunomide Concentration Is Poorly Correlated with and Has Greater Variability Than Unbound Plasma Teriflunomide ConcentrationAshley M. Hopkins, Mahin Moghaddami, David J. R. Foster, Susanna M. Proudman, Richard N. Upton and Michael D. WieseDrug Metabolism and Disposition January 2017, 45 (1) 8-16; DOI: https://doi.org/10.1124/dmd.116.071985
Montgomery, Justin
- You have accessClearance Prediction of Targeted Covalent Inhibitors by In Vitro-In Vivo Extrapolation of Hepatic and Extrahepatic Clearance MechanismsLouis Leung, Xin Yang, Timothy J. Strelevitz, Justin Montgomery, Matthew F. Brown, Michael A. Zientek, Christopher Banfield, Adam M. Gilbert, Atli Thorarensen and Martin E. DowtyDrug Metabolism and Disposition January 2017, 45 (1) 1-7; DOI: https://doi.org/10.1124/dmd.116.072983
N
Nilausen, Dorrit Østergaard
- You have accessLack of Exposure in a First-in-Man Study Due to Aldehyde Oxidase Metabolism: Investigated by Use of 14C-microdose, Humanized Mice, Monkey Pharmacokinetics, and In Vitro MethodsKlaus Gjervig Jensen, Anne-Marie Jacobsen, Christoffer Bundgaard, Dorrit Østergaard Nilausen, Zia Thale, Gamini Chandrasena and Martin JørgensenDrug Metabolism and Disposition January 2017, 45 (1) 68-75; DOI: https://doi.org/10.1124/dmd.116.072793
Ning, Miaoran
- You have accessTranscriptional Regulation of CYP2D6 ExpressionXian Pan, Miaoran Ning and Hyunyoung JeongDrug Metabolism and Disposition January 2017, 45 (1) 42-48; DOI: https://doi.org/10.1124/dmd.116.072249
O
Owens, Katie H.
- You have accessWhat Can Be Learned from Recent New Drug Applications? A Systematic Review of Drug Interaction Data for Drugs Approved by the US FDA in 2015Jingjing Yu, Zhu Zhou, Katie H. Owens, Tasha K. Ritchie and Isabelle Ragueneau-MajlessiDrug Metabolism and Disposition January 2017, 45 (1) 86-108; DOI: https://doi.org/10.1124/dmd.116.073411
P
Pan, Xian
- You have accessTranscriptional Regulation of CYP2D6 ExpressionXian Pan, Miaoran Ning and Hyunyoung JeongDrug Metabolism and Disposition January 2017, 45 (1) 42-48; DOI: https://doi.org/10.1124/dmd.116.072249
Patel, Dipal
- You have accessInhibition of Intestinal OATP2B1 by the Calcium Receptor Antagonist Ronacaleret Results in a Significant Drug-Drug Interaction by Causing a 2-Fold Decrease in Exposure of RosuvastatinMarta Johnson, Dipal Patel, Christopher Matheny, May Ho, Liangfu Chen and Harma EllensDrug Metabolism and Disposition January 2017, 45 (1) 27-34; DOI: https://doi.org/10.1124/dmd.116.072397
Proudman, Susanna M.
- You have accessIntracellular CD3+ T Lymphocyte Teriflunomide Concentration Is Poorly Correlated with and Has Greater Variability Than Unbound Plasma Teriflunomide ConcentrationAshley M. Hopkins, Mahin Moghaddami, David J. R. Foster, Susanna M. Proudman, Richard N. Upton and Michael D. WieseDrug Metabolism and Disposition January 2017, 45 (1) 8-16; DOI: https://doi.org/10.1124/dmd.116.071985
R
Ragueneau-Majlessi, Isabelle
- You have accessWhat Can Be Learned from Recent New Drug Applications? A Systematic Review of Drug Interaction Data for Drugs Approved by the US FDA in 2015Jingjing Yu, Zhu Zhou, Katie H. Owens, Tasha K. Ritchie and Isabelle Ragueneau-MajlessiDrug Metabolism and Disposition January 2017, 45 (1) 86-108; DOI: https://doi.org/10.1124/dmd.116.073411
Ray, Adrian S.
- You have accessInteraction of 2,4-Diaminopyrimidine–Containing Drugs Including Fedratinib and Trimethoprim with Thiamine TransportersMarilyn M. Giacomini, Jia Hao, Xiaomin Liang, Jayaraman Chandrasekhar, Jolyn Twelves, J. Andrew Whitney, Eve-Irene Lepist and Adrian S. RayDrug Metabolism and Disposition January 2017, 45 (1) 76-85; DOI: https://doi.org/10.1124/dmd.116.073338
Ritchie, Tasha K.
- You have accessWhat Can Be Learned from Recent New Drug Applications? A Systematic Review of Drug Interaction Data for Drugs Approved by the US FDA in 2015Jingjing Yu, Zhu Zhou, Katie H. Owens, Tasha K. Ritchie and Isabelle Ragueneau-MajlessiDrug Metabolism and Disposition January 2017, 45 (1) 86-108; DOI: https://doi.org/10.1124/dmd.116.073411
Rollison, Helen
- You have accessManaging the Risk of CYP3A Induction in Drug Development: A Strategic ApproachBarry C. Jones, Helen Rollison, Susanne Johansson, Kajsa P. Kanebratt, Craig Lambert, Karthick Vishwanathan and Tommy B. AnderssonDrug Metabolism and Disposition January 2017, 45 (1) 35-41; DOI: https://doi.org/10.1124/dmd.116.072025
Rudi de Waart, D.
- You have accessStable Overexpression of the Constitutive Androstane Receptor Reduces the Requirement for Culture with Dimethyl Sulfoxide for High Drug Metabolism in HepaRG CellsVincent A. van der Mark, D. Rudi de Waart, Valery Shevchenko, Ronald P.J. Oude Elferink, Robert A. F. M. Chamuleau and Ruurdtje HoekstraDrug Metabolism and Disposition January 2017, 45 (1) 56-67; DOI: https://doi.org/10.1124/dmd.116.072603
S
Shamsi, Suhaili
- You have accessCurcumin, Piperine, and Capsaicin: A Comparative Study of Spice-Mediated Inhibition of Human Cytochrome P450 Isozyme ActivitiesSuhaili Shamsi, Huong Tran, Renee Seok Jin Tan, Zee Jian Tan and Lee Yong LimDrug Metabolism and Disposition January 2017, 45 (1) 49-55; DOI: https://doi.org/10.1124/dmd.116.073213
Shen, Zhuowei
- You have accessHistone H3 Lysine 4 Trimethylation, Lysine 27 Trimethylation, and Lysine 27 Acetylation Contribute to the Transcriptional Repression of Solute Carrier Family 47 Member 2 in Renal Cell CarcinomaQinqin Yu, Yanqing Liu, Xiaoli Zheng, Qianying Zhu, Zhuowei Shen, Hua Wang, Huadong He, Nengming Lin, Huidi Jiang, Lushan Yu and Su ZengDrug Metabolism and Disposition January 2017, 45 (1) 109-117; DOI: https://doi.org/10.1124/dmd.116.073734
Shevchenko, Valery
- You have accessStable Overexpression of the Constitutive Androstane Receptor Reduces the Requirement for Culture with Dimethyl Sulfoxide for High Drug Metabolism in HepaRG CellsVincent A. van der Mark, D. Rudi de Waart, Valery Shevchenko, Ronald P.J. Oude Elferink, Robert A. F. M. Chamuleau and Ruurdtje HoekstraDrug Metabolism and Disposition January 2017, 45 (1) 56-67; DOI: https://doi.org/10.1124/dmd.116.072603
Strelevitz, Timothy J.
- You have accessClearance Prediction of Targeted Covalent Inhibitors by In Vitro-In Vivo Extrapolation of Hepatic and Extrahepatic Clearance MechanismsLouis Leung, Xin Yang, Timothy J. Strelevitz, Justin Montgomery, Matthew F. Brown, Michael A. Zientek, Christopher Banfield, Adam M. Gilbert, Atli Thorarensen and Martin E. DowtyDrug Metabolism and Disposition January 2017, 45 (1) 1-7; DOI: https://doi.org/10.1124/dmd.116.072983
T
Tan, Renee Seok Jin
- You have accessCurcumin, Piperine, and Capsaicin: A Comparative Study of Spice-Mediated Inhibition of Human Cytochrome P450 Isozyme ActivitiesSuhaili Shamsi, Huong Tran, Renee Seok Jin Tan, Zee Jian Tan and Lee Yong LimDrug Metabolism and Disposition January 2017, 45 (1) 49-55; DOI: https://doi.org/10.1124/dmd.116.073213
Tan, Zee Jian
- You have accessCurcumin, Piperine, and Capsaicin: A Comparative Study of Spice-Mediated Inhibition of Human Cytochrome P450 Isozyme ActivitiesSuhaili Shamsi, Huong Tran, Renee Seok Jin Tan, Zee Jian Tan and Lee Yong LimDrug Metabolism and Disposition January 2017, 45 (1) 49-55; DOI: https://doi.org/10.1124/dmd.116.073213
Thale, Zia
- You have accessLack of Exposure in a First-in-Man Study Due to Aldehyde Oxidase Metabolism: Investigated by Use of 14C-microdose, Humanized Mice, Monkey Pharmacokinetics, and In Vitro MethodsKlaus Gjervig Jensen, Anne-Marie Jacobsen, Christoffer Bundgaard, Dorrit Østergaard Nilausen, Zia Thale, Gamini Chandrasena and Martin JørgensenDrug Metabolism and Disposition January 2017, 45 (1) 68-75; DOI: https://doi.org/10.1124/dmd.116.072793
Thorarensen, Atli
- You have accessClearance Prediction of Targeted Covalent Inhibitors by In Vitro-In Vivo Extrapolation of Hepatic and Extrahepatic Clearance MechanismsLouis Leung, Xin Yang, Timothy J. Strelevitz, Justin Montgomery, Matthew F. Brown, Michael A. Zientek, Christopher Banfield, Adam M. Gilbert, Atli Thorarensen and Martin E. DowtyDrug Metabolism and Disposition January 2017, 45 (1) 1-7; DOI: https://doi.org/10.1124/dmd.116.072983
Tran, Huong
- You have accessCurcumin, Piperine, and Capsaicin: A Comparative Study of Spice-Mediated Inhibition of Human Cytochrome P450 Isozyme ActivitiesSuhaili Shamsi, Huong Tran, Renee Seok Jin Tan, Zee Jian Tan and Lee Yong LimDrug Metabolism and Disposition January 2017, 45 (1) 49-55; DOI: https://doi.org/10.1124/dmd.116.073213
Twelves, Jolyn
- You have accessInteraction of 2,4-Diaminopyrimidine–Containing Drugs Including Fedratinib and Trimethoprim with Thiamine TransportersMarilyn M. Giacomini, Jia Hao, Xiaomin Liang, Jayaraman Chandrasekhar, Jolyn Twelves, J. Andrew Whitney, Eve-Irene Lepist and Adrian S. RayDrug Metabolism and Disposition January 2017, 45 (1) 76-85; DOI: https://doi.org/10.1124/dmd.116.073338
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Upton, Richard N.
- You have accessIntracellular CD3+ T Lymphocyte Teriflunomide Concentration Is Poorly Correlated with and Has Greater Variability Than Unbound Plasma Teriflunomide ConcentrationAshley M. Hopkins, Mahin Moghaddami, David J. R. Foster, Susanna M. Proudman, Richard N. Upton and Michael D. WieseDrug Metabolism and Disposition January 2017, 45 (1) 8-16; DOI: https://doi.org/10.1124/dmd.116.071985
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van der Mark, Vincent A.
- You have accessStable Overexpression of the Constitutive Androstane Receptor Reduces the Requirement for Culture with Dimethyl Sulfoxide for High Drug Metabolism in HepaRG CellsVincent A. van der Mark, D. Rudi de Waart, Valery Shevchenko, Ronald P.J. Oude Elferink, Robert A. F. M. Chamuleau and Ruurdtje HoekstraDrug Metabolism and Disposition January 2017, 45 (1) 56-67; DOI: https://doi.org/10.1124/dmd.116.072603
Vinks, Alexander A.
- You have accessDevelopmental Changes in Hepatic Organic Cation Transporter OCT1 Protein Expression from Neonates to ChildrenDavid Hahn, Chie Emoto, Alexander A. Vinks and Tsuyoshi FukudaDrug Metabolism and Disposition January 2017, 45 (1) 23-26; DOI: https://doi.org/10.1124/dmd.116.072256
Vishwanathan, Karthick
- You have accessManaging the Risk of CYP3A Induction in Drug Development: A Strategic ApproachBarry C. Jones, Helen Rollison, Susanne Johansson, Kajsa P. Kanebratt, Craig Lambert, Karthick Vishwanathan and Tommy B. AnderssonDrug Metabolism and Disposition January 2017, 45 (1) 35-41; DOI: https://doi.org/10.1124/dmd.116.072025
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Wang, Hua
- You have accessHistone H3 Lysine 4 Trimethylation, Lysine 27 Trimethylation, and Lysine 27 Acetylation Contribute to the Transcriptional Repression of Solute Carrier Family 47 Member 2 in Renal Cell CarcinomaQinqin Yu, Yanqing Liu, Xiaoli Zheng, Qianying Zhu, Zhuowei Shen, Hua Wang, Huadong He, Nengming Lin, Huidi Jiang, Lushan Yu and Su ZengDrug Metabolism and Disposition January 2017, 45 (1) 109-117; DOI: https://doi.org/10.1124/dmd.116.073734
Whitney, J. Andrew
- You have accessInteraction of 2,4-Diaminopyrimidine–Containing Drugs Including Fedratinib and Trimethoprim with Thiamine TransportersMarilyn M. Giacomini, Jia Hao, Xiaomin Liang, Jayaraman Chandrasekhar, Jolyn Twelves, J. Andrew Whitney, Eve-Irene Lepist and Adrian S. RayDrug Metabolism and Disposition January 2017, 45 (1) 76-85; DOI: https://doi.org/10.1124/dmd.116.073338
Wiese, Michael D.
- You have accessIntracellular CD3+ T Lymphocyte Teriflunomide Concentration Is Poorly Correlated with and Has Greater Variability Than Unbound Plasma Teriflunomide ConcentrationAshley M. Hopkins, Mahin Moghaddami, David J. R. Foster, Susanna M. Proudman, Richard N. Upton and Michael D. WieseDrug Metabolism and Disposition January 2017, 45 (1) 8-16; DOI: https://doi.org/10.1124/dmd.116.071985
Wolf, C. Roland
- Open AccessApplication of Mice Humanized for CYP2D6 to the Study of Tamoxifen Metabolism and Drug–Drug Interaction with AntidepressantsA. Kenneth MacLeod, Lesley A. McLaughlin, Colin J. Henderson and C. Roland WolfDrug Metabolism and Disposition January 2017, 45 (1) 17-22; DOI: https://doi.org/10.1124/dmd.116.073437
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Yang, Xin
- You have accessClearance Prediction of Targeted Covalent Inhibitors by In Vitro-In Vivo Extrapolation of Hepatic and Extrahepatic Clearance MechanismsLouis Leung, Xin Yang, Timothy J. Strelevitz, Justin Montgomery, Matthew F. Brown, Michael A. Zientek, Christopher Banfield, Adam M. Gilbert, Atli Thorarensen and Martin E. DowtyDrug Metabolism and Disposition January 2017, 45 (1) 1-7; DOI: https://doi.org/10.1124/dmd.116.072983
Yu, Jingjing
- You have accessWhat Can Be Learned from Recent New Drug Applications? A Systematic Review of Drug Interaction Data for Drugs Approved by the US FDA in 2015Jingjing Yu, Zhu Zhou, Katie H. Owens, Tasha K. Ritchie and Isabelle Ragueneau-MajlessiDrug Metabolism and Disposition January 2017, 45 (1) 86-108; DOI: https://doi.org/10.1124/dmd.116.073411
Yu, Lushan
- You have accessHistone H3 Lysine 4 Trimethylation, Lysine 27 Trimethylation, and Lysine 27 Acetylation Contribute to the Transcriptional Repression of Solute Carrier Family 47 Member 2 in Renal Cell CarcinomaQinqin Yu, Yanqing Liu, Xiaoli Zheng, Qianying Zhu, Zhuowei Shen, Hua Wang, Huadong He, Nengming Lin, Huidi Jiang, Lushan Yu and Su ZengDrug Metabolism and Disposition January 2017, 45 (1) 109-117; DOI: https://doi.org/10.1124/dmd.116.073734
Yu, Qinqin
- You have accessHistone H3 Lysine 4 Trimethylation, Lysine 27 Trimethylation, and Lysine 27 Acetylation Contribute to the Transcriptional Repression of Solute Carrier Family 47 Member 2 in Renal Cell CarcinomaQinqin Yu, Yanqing Liu, Xiaoli Zheng, Qianying Zhu, Zhuowei Shen, Hua Wang, Huadong He, Nengming Lin, Huidi Jiang, Lushan Yu and Su ZengDrug Metabolism and Disposition January 2017, 45 (1) 109-117; DOI: https://doi.org/10.1124/dmd.116.073734
Z
Zeng, Su
- You have accessHistone H3 Lysine 4 Trimethylation, Lysine 27 Trimethylation, and Lysine 27 Acetylation Contribute to the Transcriptional Repression of Solute Carrier Family 47 Member 2 in Renal Cell CarcinomaQinqin Yu, Yanqing Liu, Xiaoli Zheng, Qianying Zhu, Zhuowei Shen, Hua Wang, Huadong He, Nengming Lin, Huidi Jiang, Lushan Yu and Su ZengDrug Metabolism and Disposition January 2017, 45 (1) 109-117; DOI: https://doi.org/10.1124/dmd.116.073734
Zheng, Xiaoli
- You have accessHistone H3 Lysine 4 Trimethylation, Lysine 27 Trimethylation, and Lysine 27 Acetylation Contribute to the Transcriptional Repression of Solute Carrier Family 47 Member 2 in Renal Cell CarcinomaQinqin Yu, Yanqing Liu, Xiaoli Zheng, Qianying Zhu, Zhuowei Shen, Hua Wang, Huadong He, Nengming Lin, Huidi Jiang, Lushan Yu and Su ZengDrug Metabolism and Disposition January 2017, 45 (1) 109-117; DOI: https://doi.org/10.1124/dmd.116.073734
Zhou, Zhu
- You have accessWhat Can Be Learned from Recent New Drug Applications? A Systematic Review of Drug Interaction Data for Drugs Approved by the US FDA in 2015Jingjing Yu, Zhu Zhou, Katie H. Owens, Tasha K. Ritchie and Isabelle Ragueneau-MajlessiDrug Metabolism and Disposition January 2017, 45 (1) 86-108; DOI: https://doi.org/10.1124/dmd.116.073411
Zhu, Qianying
- You have accessHistone H3 Lysine 4 Trimethylation, Lysine 27 Trimethylation, and Lysine 27 Acetylation Contribute to the Transcriptional Repression of Solute Carrier Family 47 Member 2 in Renal Cell CarcinomaQinqin Yu, Yanqing Liu, Xiaoli Zheng, Qianying Zhu, Zhuowei Shen, Hua Wang, Huadong He, Nengming Lin, Huidi Jiang, Lushan Yu and Su ZengDrug Metabolism and Disposition January 2017, 45 (1) 109-117; DOI: https://doi.org/10.1124/dmd.116.073734
Zientek, Michael A.
- You have accessClearance Prediction of Targeted Covalent Inhibitors by In Vitro-In Vivo Extrapolation of Hepatic and Extrahepatic Clearance MechanismsLouis Leung, Xin Yang, Timothy J. Strelevitz, Justin Montgomery, Matthew F. Brown, Michael A. Zientek, Christopher Banfield, Adam M. Gilbert, Atli Thorarensen and Martin E. DowtyDrug Metabolism and Disposition January 2017, 45 (1) 1-7; DOI: https://doi.org/10.1124/dmd.116.072983
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