Table of Contents

Articles

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  Wuzhi Tablet (Schisandra sphenanthera Extract) Is a Promising Tacrolimus-Sparing Agent for Renal Transplant Recipients Who Are CYP3A5 Expressers: a Two-Phase Prospective Study

  Jiali Li, Siyang Chen, Xiaoling Qin, Qian Fu, Huichang Bi, Yu Zhang, Xueding Wang, Longshan Liu, Changxi Wang and Min Huang

  Drug Metabolism and Disposition November 2017, 45 (11) 1114-1119; DOI: https://doi.org/10.1124/dmd.117.076737
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  Measurement and Mathematical Characterization of Cell-Level Pharmacokinetics of Antibody-Drug Conjugates: A Case Study with Trastuzumab-vc-MMAE

  Aman P. Singh and Dhaval K. Shah

  Drug Metabolism and Disposition November 2017, 45 (11) 1120-1132; DOI: https://doi.org/10.1124/dmd.117.076414
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  CYP-Mediated Sulfoximine Deimination of AZD6738

  Barry C. Jones, Roshini Markandu, Chungang Gu and Graeme Scarfe

  Drug Metabolism and Disposition November 2017, 45 (11) 1133-1138; DOI: https://doi.org/10.1124/dmd.117.077776
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  Simple Evaluation Method for CYP3A4 Induction from Human Hepatocytes: The Relative Factor Approach with an Induction Detection Limit Concentration Based on the E_max Model

  Shino Kuramoto, Motohiro Kato, Hidetoshi Shindoh, Akihisa Kaneko, Masaki Ishigai and Seiji Miyauchi

  Drug Metabolism and Disposition November 2017, 45 (11) 1139-1145; DOI: https://doi.org/10.1124/dmd.117.076349
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  A Comprehensive Functional Assessment of Carboxylesterase 1 Nonsynonymous Polymorphisms

  Xinwen Wang, Nada Rida, Jian Shi, Audrey H. Wu, Barry E. Bleske and Hao-Jie Zhu

  Drug Metabolism and Disposition November 2017, 45 (11) 1149-1155; DOI: https://doi.org/10.1124/dmd.117.077669
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  Physiologically Based Pharmacokinetic Model of the CYP2D6 Probe Atomoxetine: Extrapolation to Special Populations and Drug-Drug Interactions

  Weize Huang, Mariko Nakano, Jennifer Sager, Isabelle Ragueneau-Majlessi and Nina Isoherranen

  Drug Metabolism and Disposition November 2017, 45 (11) 1156-1165; DOI: https://doi.org/10.1124/dmd.117.076455
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  Synthetic Analogs of Curcumin Modulate the Function of Multidrug Resistance–Linked ATP-Binding Cassette Transporter ABCG2

  Megumi Murakami, Shinobu Ohnuma, Michihiro Fukuda, Eduardo E. Chufan, Katsuyoshi Kudoh, Keigo Kanehara, Norihiko Sugisawa, Masaharu Ishida, Takeshi Naitoh, Hiroyuki Shibata, Yoshiharu Iwabuchi, Suresh V. Ambudkar and Michiaki Unno

  Drug Metabolism and Disposition November 2017, 45 (11) 1166-1177; DOI: https://doi.org/10.1124/dmd.117.076000
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  Hepatic Flavin-Containing Monooxygenase 3 Enzyme Suppressed by Type 1 Allergy-Produced Nitric Oxide

  Tadatoshi Tanino, Toru Bando, Akira Komada, Yukie Nojiri, Yuna Okada, Yukari Ueda and Eiichi Sakurai

  Drug Metabolism and Disposition November 2017, 45 (11) 1189-1196; DOI: https://doi.org/10.1124/dmd.117.076570
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  Novel Interactions between Gut Microbiome and Host Drug-Processing Genes Modify the Hepatic Metabolism of the Environmental Chemicals Polybrominated Diphenyl Ethers

  Cindy Yanfei Li, Soowan Lee, Sara Cade, Li-Jung Kuo, Irvin R. Schultz, Deepak K. Bhatt, Bhagwat Prasad, Theo K. Bammler and Julia Yue Cui

  Drug Metabolism and Disposition November 2017, 45 (11) 1197-1214; DOI: https://doi.org/10.1124/dmd.117.077024