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Expression and Functional Characterization of Breast Cancer-Associated Cytochrome P450 4Z1 in Saccharomyces cerevisiae

Matthew G. McDonald, Sutapa Ray, Clara J. Amorosi, Katherine A. Sitko, John P. Kowalski, Lorela Paco, Abhinav Nath, Byron Gallis, Rheem A. Totah, Maitreya J. Dunham, Douglas M. Fowler and Allan E. Rettie
Drug Metabolism and Disposition December 2017, 45 (12) 1364-1371; DOI: https://doi.org/10.1124/dmd.117.078188

Article Information

vol. 45 no. 12 1364-1371
DOI 
https://doi.org/10.1124/dmd.117.078188
PubMed 
29018033
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received August 19, 2017
  • Accepted October 4, 2017
  • Published online November 20, 2017.

Article Versions

Copyright & Usage 
Copyright © 2017 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Matthew G. McDonald,
  2. Sutapa Ray,
  3. Clara J. Amorosi,
  4. Katherine A. Sitko,
  5. John P. Kowalski,
  6. Lorela Paco,
  7. Abhinav Nath,
  8. Byron Gallis,
  9. Rheem A. Totah,
  10. Maitreya J. Dunham,
  11. Douglas M. Fowler, and
  12. Allan E. Rettie
  1. Departments of Medicinal Chemistry (M.G.M., S.R., J.P.K., L.P., A.N., B.G., R.A.T., A.E.R.), Genome Sciences (K.A.S., C.J.A., M.J.D., D.M.F.), and Bioengineering (D.M.F.), University of Washington, Seattle, Washington
  1. Address correspondence to:
    Dr. Allan E. Rettie, Department of Medicinal Chemistry, University of Washington, Box 357610, 1959 NE Pacific, Seattle, WA 98195. E-mail: rettie{at}uw.edu
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Catalytic Activity of CYP4Z1

Matthew G. McDonald, Sutapa Ray, Clara J. Amorosi, Katherine A. Sitko, John P. Kowalski, Lorela Paco, Abhinav Nath, Byron Gallis, Rheem A. Totah, Maitreya J. Dunham, Douglas M. Fowler and Allan E. Rettie
Drug Metabolism and Disposition December 1, 2017, 45 (12) 1364-1371; DOI: https://doi.org/10.1124/dmd.117.078188
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