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Drug Metabolism & Disposition

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  • Articles
    • Current Issue
    • Fast Forward
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Index by author

February 01, 2017; Volume 45,Issue 2
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Agnani, Deep

    1. You have access
      Microvilli Morphology Can Affect Efflux Active P-Glycoprotein in Confluent MDCKII -hMDR1-NKI and Caco-2 Cell Monolayers
      Zhou Meng, Sylvain Le Marchand, Deep Agnani, Matthew Szapacs, Harma Ellens and Joe Bentz
      Drug Metabolism and Disposition February 2017, 45 (2) 145-151; DOI: https://doi.org/10.1124/dmd.116.072157
  2. Ahituv, Nadav

    1. You have access
      In Vivo Hepatic Enhancer Elements in the Human ABCG2 Locus
      Rachel J. Eclov, Mee J. Kim, Robin P. Smith, Xiaomin Liang, Nadav Ahituv and Deanna L. Kroetz
      Drug Metabolism and Disposition February 2017, 45 (2) 208-215; DOI: https://doi.org/10.1124/dmd.116.072033
  3. Annes, William F.

    1. Open Access
      In Vitro and Clinical Evaluations of the Drug-Drug Interaction Potential of a Metabotropic Glutamate 2/3 Receptor Agonist Prodrug with Intestinal Peptide Transporter 1
      Y. Anne Pak, Amanda J. Long, William F. Annes, Jennifer W. Witcher, Mary Pat Knadler, Mosun A. Ayan-Oshodi, Malcolm I. Mitchell, Phillip Leese and Kathleen M. Hillgren
      Drug Metabolism and Disposition February 2017, 45 (2) 137-144; DOI: https://doi.org/10.1124/dmd.116.071118
  4. Asakura, Mitsutoshi

    1. You have access
      Hepatic Dipeptidyl Peptidase-4 Controls Pharmacokinetics of Vildagliptin In Vivo
      Mitsutoshi Asakura, Tatsuki Fukami, Miki Nakajima, Hideaki Fujii, Koichiro Atsuda, Tomoo Itoh and Ryoichi Fujiwara
      Drug Metabolism and Disposition February 2017, 45 (2) 237-245; DOI: https://doi.org/10.1124/dmd.116.073866
  5. Atsuda, Koichiro

    1. You have access
      Hepatic Dipeptidyl Peptidase-4 Controls Pharmacokinetics of Vildagliptin In Vivo
      Mitsutoshi Asakura, Tatsuki Fukami, Miki Nakajima, Hideaki Fujii, Koichiro Atsuda, Tomoo Itoh and Ryoichi Fujiwara
      Drug Metabolism and Disposition February 2017, 45 (2) 237-245; DOI: https://doi.org/10.1124/dmd.116.073866
  6. Ayan-Oshodi, Mosun A.

    1. Open Access
      In Vitro and Clinical Evaluations of the Drug-Drug Interaction Potential of a Metabotropic Glutamate 2/3 Receptor Agonist Prodrug with Intestinal Peptide Transporter 1
      Y. Anne Pak, Amanda J. Long, William F. Annes, Jennifer W. Witcher, Mary Pat Knadler, Mosun A. Ayan-Oshodi, Malcolm I. Mitchell, Phillip Leese and Kathleen M. Hillgren
      Drug Metabolism and Disposition February 2017, 45 (2) 137-144; DOI: https://doi.org/10.1124/dmd.116.071118

B

  1. Bellanti, Francisco

    1. You have access
      Target-Site Investigation for the Plasma Prolactin Response: Mechanism-Based Pharmacokinetic-Pharmacodynamic Analysis of Risperidone and Paliperidone in the Rat
      Shinji Shimizu, Sandra M. den Hoedt, Victor Mangas-Sanjuan, Sinziana Cristea, Jana K. Geuer, Dirk-Jan van den Berg, Robin Hartman, Francisco Bellanti and Elizabeth C. M. de Lange
      Drug Metabolism and Disposition February 2017, 45 (2) 152-159; DOI: https://doi.org/10.1124/dmd.116.072306
  2. Bennink, Roelof J.

    1. You have access
      Impact of Organic Cation Transporters (OCT-SLC22A) on Differential Diagnosis of Intrahepatic Lesions
      Michele Visentin, Belle V. van Rosmalen, Christian Hiller, Matthanja Bieze, Lia Hofstetter, Joanne Verheij, Gerd A. Kullak-Ublick, Hermann Koepsell, Saffire S.K.S. Phoa, Ikumi Tamai, Roelof J. Bennink, Thomas M. van Gulik and Bruno Stieger
      Drug Metabolism and Disposition February 2017, 45 (2) 166-173; DOI: https://doi.org/10.1124/dmd.116.072371
  3. Benoit, Etienne

    1. You have access
      Management of Rodent Populations by Anticoagulant Rodenticides: Toward Third-Generation Anticoagulant Rodenticides
      Marlène Damin-Pernik, Bernadette Espana, Sebastien Lefebvre, Isabelle Fourel, Hervé Caruel, Etienne Benoit and Virginie Lattard
      Drug Metabolism and Disposition February 2017, 45 (2) 160-165; DOI: https://doi.org/10.1124/dmd.116.073791
  4. Bentz, Joe

    1. You have access
      Extrapolation of Elementary Rate Constants of P-glycoprotein–Mediated Transport from MDCKII-hMDR1-NKI to Caco-2 Cells
      Zhou Meng, Harma Ellens and Joe Bentz
      Drug Metabolism and Disposition February 2017, 45 (2) 190-197; DOI: https://doi.org/10.1124/dmd.116.072140
    2. You have access
      Microvilli Morphology Can Affect Efflux Active P-Glycoprotein in Confluent MDCKII -hMDR1-NKI and Caco-2 Cell Monolayers
      Zhou Meng, Sylvain Le Marchand, Deep Agnani, Matthew Szapacs, Harma Ellens and Joe Bentz
      Drug Metabolism and Disposition February 2017, 45 (2) 145-151; DOI: https://doi.org/10.1124/dmd.116.072157
  5. Bhatt, Deepak Kumar

    1. You have access
      Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants
      Mikael Boberg, Marc Vrana, Aanchal Mehrotra, Robin E. Pearce, Andrea Gaedigk, Deepak Kumar Bhatt, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition February 2017, 45 (2) 216-223; DOI: https://doi.org/10.1124/dmd.116.072652
  6. Bieze, Matthanja

    1. You have access
      Impact of Organic Cation Transporters (OCT-SLC22A) on Differential Diagnosis of Intrahepatic Lesions
      Michele Visentin, Belle V. van Rosmalen, Christian Hiller, Matthanja Bieze, Lia Hofstetter, Joanne Verheij, Gerd A. Kullak-Ublick, Hermann Koepsell, Saffire S.K.S. Phoa, Ikumi Tamai, Roelof J. Bennink, Thomas M. van Gulik and Bruno Stieger
      Drug Metabolism and Disposition February 2017, 45 (2) 166-173; DOI: https://doi.org/10.1124/dmd.116.072371
  7. Boberg, Mikael

    1. You have access
      Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants
      Mikael Boberg, Marc Vrana, Aanchal Mehrotra, Robin E. Pearce, Andrea Gaedigk, Deepak Kumar Bhatt, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition February 2017, 45 (2) 216-223; DOI: https://doi.org/10.1124/dmd.116.072652

C

  1. Cao, Li

    1. Open Access
      Evaluation of a Novel Renewable Hepatic Cell Model for Prediction of Clinical CYP3A4 Induction Using a Correlation-Based Relative Induction Score Approach
      Rongjun Zuo, Feng Li, Sweta Parikh, Li Cao, Kirsten L. Cooper, Yulong Hong, Jin Liu, Ronald A. Faris, Daochuan Li and Hongbing Wang
      Drug Metabolism and Disposition February 2017, 45 (2) 198-207; DOI: https://doi.org/10.1124/dmd.116.072124
  2. Caruel, Hervé

    1. You have access
      Management of Rodent Populations by Anticoagulant Rodenticides: Toward Third-Generation Anticoagulant Rodenticides
      Marlène Damin-Pernik, Bernadette Espana, Sebastien Lefebvre, Isabelle Fourel, Hervé Caruel, Etienne Benoit and Virginie Lattard
      Drug Metabolism and Disposition February 2017, 45 (2) 160-165; DOI: https://doi.org/10.1124/dmd.116.073791
  3. Cooper, Kirsten L.

    1. Open Access
      Evaluation of a Novel Renewable Hepatic Cell Model for Prediction of Clinical CYP3A4 Induction Using a Correlation-Based Relative Induction Score Approach
      Rongjun Zuo, Feng Li, Sweta Parikh, Li Cao, Kirsten L. Cooper, Yulong Hong, Jin Liu, Ronald A. Faris, Daochuan Li and Hongbing Wang
      Drug Metabolism and Disposition February 2017, 45 (2) 198-207; DOI: https://doi.org/10.1124/dmd.116.072124
  4. Cristea, Sinziana

    1. You have access
      Target-Site Investigation for the Plasma Prolactin Response: Mechanism-Based Pharmacokinetic-Pharmacodynamic Analysis of Risperidone and Paliperidone in the Rat
      Shinji Shimizu, Sandra M. den Hoedt, Victor Mangas-Sanjuan, Sinziana Cristea, Jana K. Geuer, Dirk-Jan van den Berg, Robin Hartman, Francisco Bellanti and Elizabeth C. M. de Lange
      Drug Metabolism and Disposition February 2017, 45 (2) 152-159; DOI: https://doi.org/10.1124/dmd.116.072306

D

  1. Damin-Pernik, Marlène

    1. You have access
      Management of Rodent Populations by Anticoagulant Rodenticides: Toward Third-Generation Anticoagulant Rodenticides
      Marlène Damin-Pernik, Bernadette Espana, Sebastien Lefebvre, Isabelle Fourel, Hervé Caruel, Etienne Benoit and Virginie Lattard
      Drug Metabolism and Disposition February 2017, 45 (2) 160-165; DOI: https://doi.org/10.1124/dmd.116.073791
  2. de Lange, Elizabeth C. M.

    1. You have access
      Target-Site Investigation for the Plasma Prolactin Response: Mechanism-Based Pharmacokinetic-Pharmacodynamic Analysis of Risperidone and Paliperidone in the Rat
      Shinji Shimizu, Sandra M. den Hoedt, Victor Mangas-Sanjuan, Sinziana Cristea, Jana K. Geuer, Dirk-Jan van den Berg, Robin Hartman, Francisco Bellanti and Elizabeth C. M. de Lange
      Drug Metabolism and Disposition February 2017, 45 (2) 152-159; DOI: https://doi.org/10.1124/dmd.116.072306
  3. den Hoedt, Sandra M.

    1. You have access
      Target-Site Investigation for the Plasma Prolactin Response: Mechanism-Based Pharmacokinetic-Pharmacodynamic Analysis of Risperidone and Paliperidone in the Rat
      Shinji Shimizu, Sandra M. den Hoedt, Victor Mangas-Sanjuan, Sinziana Cristea, Jana K. Geuer, Dirk-Jan van den Berg, Robin Hartman, Francisco Bellanti and Elizabeth C. M. de Lange
      Drug Metabolism and Disposition February 2017, 45 (2) 152-159; DOI: https://doi.org/10.1124/dmd.116.072306

E

  1. Eclov, Rachel J.

    1. You have access
      In Vivo Hepatic Enhancer Elements in the Human ABCG2 Locus
      Rachel J. Eclov, Mee J. Kim, Robin P. Smith, Xiaomin Liang, Nadav Ahituv and Deanna L. Kroetz
      Drug Metabolism and Disposition February 2017, 45 (2) 208-215; DOI: https://doi.org/10.1124/dmd.116.072033
  2. Ellens, Harma

    1. You have access
      Extrapolation of Elementary Rate Constants of P-glycoprotein–Mediated Transport from MDCKII-hMDR1-NKI to Caco-2 Cells
      Zhou Meng, Harma Ellens and Joe Bentz
      Drug Metabolism and Disposition February 2017, 45 (2) 190-197; DOI: https://doi.org/10.1124/dmd.116.072140
    2. You have access
      Microvilli Morphology Can Affect Efflux Active P-Glycoprotein in Confluent MDCKII -hMDR1-NKI and Caco-2 Cell Monolayers
      Zhou Meng, Sylvain Le Marchand, Deep Agnani, Matthew Szapacs, Harma Ellens and Joe Bentz
      Drug Metabolism and Disposition February 2017, 45 (2) 145-151; DOI: https://doi.org/10.1124/dmd.116.072157
  3. Espana, Bernadette

    1. You have access
      Management of Rodent Populations by Anticoagulant Rodenticides: Toward Third-Generation Anticoagulant Rodenticides
      Marlène Damin-Pernik, Bernadette Espana, Sebastien Lefebvre, Isabelle Fourel, Hervé Caruel, Etienne Benoit and Virginie Lattard
      Drug Metabolism and Disposition February 2017, 45 (2) 160-165; DOI: https://doi.org/10.1124/dmd.116.073791

F

  1. Faris, Ronald A.

    1. Open Access
      Evaluation of a Novel Renewable Hepatic Cell Model for Prediction of Clinical CYP3A4 Induction Using a Correlation-Based Relative Induction Score Approach
      Rongjun Zuo, Feng Li, Sweta Parikh, Li Cao, Kirsten L. Cooper, Yulong Hong, Jin Liu, Ronald A. Faris, Daochuan Li and Hongbing Wang
      Drug Metabolism and Disposition February 2017, 45 (2) 198-207; DOI: https://doi.org/10.1124/dmd.116.072124
  2. Fourel, Isabelle

    1. You have access
      Management of Rodent Populations by Anticoagulant Rodenticides: Toward Third-Generation Anticoagulant Rodenticides
      Marlène Damin-Pernik, Bernadette Espana, Sebastien Lefebvre, Isabelle Fourel, Hervé Caruel, Etienne Benoit and Virginie Lattard
      Drug Metabolism and Disposition February 2017, 45 (2) 160-165; DOI: https://doi.org/10.1124/dmd.116.073791
  3. Fujii, Hideaki

    1. You have access
      Hepatic Dipeptidyl Peptidase-4 Controls Pharmacokinetics of Vildagliptin In Vivo
      Mitsutoshi Asakura, Tatsuki Fukami, Miki Nakajima, Hideaki Fujii, Koichiro Atsuda, Tomoo Itoh and Ryoichi Fujiwara
      Drug Metabolism and Disposition February 2017, 45 (2) 237-245; DOI: https://doi.org/10.1124/dmd.116.073866
  4. Fujiwara, Ryoichi

    1. You have access
      Hepatic Dipeptidyl Peptidase-4 Controls Pharmacokinetics of Vildagliptin In Vivo
      Mitsutoshi Asakura, Tatsuki Fukami, Miki Nakajima, Hideaki Fujii, Koichiro Atsuda, Tomoo Itoh and Ryoichi Fujiwara
      Drug Metabolism and Disposition February 2017, 45 (2) 237-245; DOI: https://doi.org/10.1124/dmd.116.073866
  5. Fukami, Tatsuki

    1. You have access
      Hepatic Dipeptidyl Peptidase-4 Controls Pharmacokinetics of Vildagliptin In Vivo
      Mitsutoshi Asakura, Tatsuki Fukami, Miki Nakajima, Hideaki Fujii, Koichiro Atsuda, Tomoo Itoh and Ryoichi Fujiwara
      Drug Metabolism and Disposition February 2017, 45 (2) 237-245; DOI: https://doi.org/10.1124/dmd.116.073866

G

  1. Gaedigk, Andrea

    1. You have access
      Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants
      Mikael Boberg, Marc Vrana, Aanchal Mehrotra, Robin E. Pearce, Andrea Gaedigk, Deepak Kumar Bhatt, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition February 2017, 45 (2) 216-223; DOI: https://doi.org/10.1124/dmd.116.072652
  2. Geuer, Jana K.

    1. You have access
      Target-Site Investigation for the Plasma Prolactin Response: Mechanism-Based Pharmacokinetic-Pharmacodynamic Analysis of Risperidone and Paliperidone in the Rat
      Shinji Shimizu, Sandra M. den Hoedt, Victor Mangas-Sanjuan, Sinziana Cristea, Jana K. Geuer, Dirk-Jan van den Berg, Robin Hartman, Francisco Bellanti and Elizabeth C. M. de Lange
      Drug Metabolism and Disposition February 2017, 45 (2) 152-159; DOI: https://doi.org/10.1124/dmd.116.072306
  3. Grey, Anne K. Mullen

    1. You have access
      Role of Glucocorticoid Receptor and Pregnane X Receptor in Dexamethasone Induction of Rat Hepatic Aryl Hydrocarbon Receptor Nuclear Translocator and NADPH-Cytochrome P450 Oxidoreductase
      Sarah R. Hunter, Alex Vonk, Anne K. Mullen Grey and David S. Riddick
      Drug Metabolism and Disposition February 2017, 45 (2) 118-129; DOI: https://doi.org/10.1124/dmd.116.073833

H

  1. Hartman, Robin

    1. You have access
      Target-Site Investigation for the Plasma Prolactin Response: Mechanism-Based Pharmacokinetic-Pharmacodynamic Analysis of Risperidone and Paliperidone in the Rat
      Shinji Shimizu, Sandra M. den Hoedt, Victor Mangas-Sanjuan, Sinziana Cristea, Jana K. Geuer, Dirk-Jan van den Berg, Robin Hartman, Francisco Bellanti and Elizabeth C. M. de Lange
      Drug Metabolism and Disposition February 2017, 45 (2) 152-159; DOI: https://doi.org/10.1124/dmd.116.072306
  2. Hiller, Christian

    1. You have access
      Impact of Organic Cation Transporters (OCT-SLC22A) on Differential Diagnosis of Intrahepatic Lesions
      Michele Visentin, Belle V. van Rosmalen, Christian Hiller, Matthanja Bieze, Lia Hofstetter, Joanne Verheij, Gerd A. Kullak-Ublick, Hermann Koepsell, Saffire S.K.S. Phoa, Ikumi Tamai, Roelof J. Bennink, Thomas M. van Gulik and Bruno Stieger
      Drug Metabolism and Disposition February 2017, 45 (2) 166-173; DOI: https://doi.org/10.1124/dmd.116.072371
  3. Hillgren, Kathleen M.

    1. Open Access
      In Vitro and Clinical Evaluations of the Drug-Drug Interaction Potential of a Metabotropic Glutamate 2/3 Receptor Agonist Prodrug with Intestinal Peptide Transporter 1
      Y. Anne Pak, Amanda J. Long, William F. Annes, Jennifer W. Witcher, Mary Pat Knadler, Mosun A. Ayan-Oshodi, Malcolm I. Mitchell, Phillip Leese and Kathleen M. Hillgren
      Drug Metabolism and Disposition February 2017, 45 (2) 137-144; DOI: https://doi.org/10.1124/dmd.116.071118
  4. Hofstetter, Lia

    1. You have access
      Impact of Organic Cation Transporters (OCT-SLC22A) on Differential Diagnosis of Intrahepatic Lesions
      Michele Visentin, Belle V. van Rosmalen, Christian Hiller, Matthanja Bieze, Lia Hofstetter, Joanne Verheij, Gerd A. Kullak-Ublick, Hermann Koepsell, Saffire S.K.S. Phoa, Ikumi Tamai, Roelof J. Bennink, Thomas M. van Gulik and Bruno Stieger
      Drug Metabolism and Disposition February 2017, 45 (2) 166-173; DOI: https://doi.org/10.1124/dmd.116.072371
  5. Hong, Yulong

    1. Open Access
      Evaluation of a Novel Renewable Hepatic Cell Model for Prediction of Clinical CYP3A4 Induction Using a Correlation-Based Relative Induction Score Approach
      Rongjun Zuo, Feng Li, Sweta Parikh, Li Cao, Kirsten L. Cooper, Yulong Hong, Jin Liu, Ronald A. Faris, Daochuan Li and Hongbing Wang
      Drug Metabolism and Disposition February 2017, 45 (2) 198-207; DOI: https://doi.org/10.1124/dmd.116.072124
  6. Hu, Yongjun

    1. You have access
      Species Differences in Human and Rodent PEPT2-Mediated Transport of Glycylsarcosine and Cefadroxil in Pichia Pastoris Transformants
      Feifeng Song, Yongjun Hu, Huidi Jiang and David E. Smith
      Drug Metabolism and Disposition February 2017, 45 (2) 130-136; DOI: https://doi.org/10.1124/dmd.116.073320
  7. Hunter, Sarah R.

    1. You have access
      Role of Glucocorticoid Receptor and Pregnane X Receptor in Dexamethasone Induction of Rat Hepatic Aryl Hydrocarbon Receptor Nuclear Translocator and NADPH-Cytochrome P450 Oxidoreductase
      Sarah R. Hunter, Alex Vonk, Anne K. Mullen Grey and David S. Riddick
      Drug Metabolism and Disposition February 2017, 45 (2) 118-129; DOI: https://doi.org/10.1124/dmd.116.073833

I

  1. Itoh, Tomoo

    1. You have access
      Hepatic Dipeptidyl Peptidase-4 Controls Pharmacokinetics of Vildagliptin In Vivo
      Mitsutoshi Asakura, Tatsuki Fukami, Miki Nakajima, Hideaki Fujii, Koichiro Atsuda, Tomoo Itoh and Ryoichi Fujiwara
      Drug Metabolism and Disposition February 2017, 45 (2) 237-245; DOI: https://doi.org/10.1124/dmd.116.073866

J

  1. Jiang, Huidi

    1. You have access
      Species Differences in Human and Rodent PEPT2-Mediated Transport of Glycylsarcosine and Cefadroxil in Pichia Pastoris Transformants
      Feifeng Song, Yongjun Hu, Huidi Jiang and David E. Smith
      Drug Metabolism and Disposition February 2017, 45 (2) 130-136; DOI: https://doi.org/10.1124/dmd.116.073320
  2. Johne, Andreas

    1. Metabolism of the MEK1/2 Inhibitor Pimasertib Involves a Novel Conjugation with Phosphoethanolamine in Patients with Solid Tumors
      You have access
      Metabolism of the MEK1/2 Inhibitor Pimasertib Involves a Novel Conjugation with Phosphoethanolamine in Patients with Solid Tumors
      Holger Scheible, Friedrich Kraetzer, Andreas Marx, Andreas Johne and Elmar Wimmer
      Drug Metabolism and Disposition February 2017, 45 (2) 174-182; DOI: https://doi.org/10.1124/dmd.116.072934

K

  1. Kim, Mee J.

    1. You have access
      In Vivo Hepatic Enhancer Elements in the Human ABCG2 Locus
      Rachel J. Eclov, Mee J. Kim, Robin P. Smith, Xiaomin Liang, Nadav Ahituv and Deanna L. Kroetz
      Drug Metabolism and Disposition February 2017, 45 (2) 208-215; DOI: https://doi.org/10.1124/dmd.116.072033
  2. Knadler, Mary Pat

    1. Open Access
      In Vitro and Clinical Evaluations of the Drug-Drug Interaction Potential of a Metabotropic Glutamate 2/3 Receptor Agonist Prodrug with Intestinal Peptide Transporter 1
      Y. Anne Pak, Amanda J. Long, William F. Annes, Jennifer W. Witcher, Mary Pat Knadler, Mosun A. Ayan-Oshodi, Malcolm I. Mitchell, Phillip Leese and Kathleen M. Hillgren
      Drug Metabolism and Disposition February 2017, 45 (2) 137-144; DOI: https://doi.org/10.1124/dmd.116.071118
  3. Koepsell, Hermann

    1. You have access
      Impact of Organic Cation Transporters (OCT-SLC22A) on Differential Diagnosis of Intrahepatic Lesions
      Michele Visentin, Belle V. van Rosmalen, Christian Hiller, Matthanja Bieze, Lia Hofstetter, Joanne Verheij, Gerd A. Kullak-Ublick, Hermann Koepsell, Saffire S.K.S. Phoa, Ikumi Tamai, Roelof J. Bennink, Thomas M. van Gulik and Bruno Stieger
      Drug Metabolism and Disposition February 2017, 45 (2) 166-173; DOI: https://doi.org/10.1124/dmd.116.072371
  4. Kraetzer, Friedrich

    1. Metabolism of the MEK1/2 Inhibitor Pimasertib Involves a Novel Conjugation with Phosphoethanolamine in Patients with Solid Tumors
      You have access
      Metabolism of the MEK1/2 Inhibitor Pimasertib Involves a Novel Conjugation with Phosphoethanolamine in Patients with Solid Tumors
      Holger Scheible, Friedrich Kraetzer, Andreas Marx, Andreas Johne and Elmar Wimmer
      Drug Metabolism and Disposition February 2017, 45 (2) 174-182; DOI: https://doi.org/10.1124/dmd.116.072934
  5. Kroetz, Deanna L.

    1. You have access
      In Vivo Hepatic Enhancer Elements in the Human ABCG2 Locus
      Rachel J. Eclov, Mee J. Kim, Robin P. Smith, Xiaomin Liang, Nadav Ahituv and Deanna L. Kroetz
      Drug Metabolism and Disposition February 2017, 45 (2) 208-215; DOI: https://doi.org/10.1124/dmd.116.072033
  6. Kullak-Ublick, Gerd A.

    1. You have access
      Impact of Organic Cation Transporters (OCT-SLC22A) on Differential Diagnosis of Intrahepatic Lesions
      Michele Visentin, Belle V. van Rosmalen, Christian Hiller, Matthanja Bieze, Lia Hofstetter, Joanne Verheij, Gerd A. Kullak-Ublick, Hermann Koepsell, Saffire S.K.S. Phoa, Ikumi Tamai, Roelof J. Bennink, Thomas M. van Gulik and Bruno Stieger
      Drug Metabolism and Disposition February 2017, 45 (2) 166-173; DOI: https://doi.org/10.1124/dmd.116.072371

L

  1. Lai, W. George

    1. You have access
      Impact of Probe Substrate Selection on Cytochrome P450 Reaction Phenotyping Using the Relative Activity Factor
      Y. Amy Siu and W. George Lai
      Drug Metabolism and Disposition February 2017, 45 (2) 183-189; DOI: https://doi.org/10.1124/dmd.116.073510
  2. Lai, Yurong

    1. You have access
      Organic Anion Transporter 2: An Enigmatic Human Solute Carrier
      Hong Shen, Yurong Lai and A. David Rodrigues
      Drug Metabolism and Disposition February 2017, 45 (2) 228-236; DOI: https://doi.org/10.1124/dmd.116.072264
  3. Lattard, Virginie

    1. You have access
      Management of Rodent Populations by Anticoagulant Rodenticides: Toward Third-Generation Anticoagulant Rodenticides
      Marlène Damin-Pernik, Bernadette Espana, Sebastien Lefebvre, Isabelle Fourel, Hervé Caruel, Etienne Benoit and Virginie Lattard
      Drug Metabolism and Disposition February 2017, 45 (2) 160-165; DOI: https://doi.org/10.1124/dmd.116.073791
  4. Leeder, J. Steven

    1. You have access
      Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants
      Mikael Boberg, Marc Vrana, Aanchal Mehrotra, Robin E. Pearce, Andrea Gaedigk, Deepak Kumar Bhatt, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition February 2017, 45 (2) 216-223; DOI: https://doi.org/10.1124/dmd.116.072652
  5. Leese, Phillip

    1. Open Access
      In Vitro and Clinical Evaluations of the Drug-Drug Interaction Potential of a Metabotropic Glutamate 2/3 Receptor Agonist Prodrug with Intestinal Peptide Transporter 1
      Y. Anne Pak, Amanda J. Long, William F. Annes, Jennifer W. Witcher, Mary Pat Knadler, Mosun A. Ayan-Oshodi, Malcolm I. Mitchell, Phillip Leese and Kathleen M. Hillgren
      Drug Metabolism and Disposition February 2017, 45 (2) 137-144; DOI: https://doi.org/10.1124/dmd.116.071118
  6. Lefebvre, Sebastien

    1. You have access
      Management of Rodent Populations by Anticoagulant Rodenticides: Toward Third-Generation Anticoagulant Rodenticides
      Marlène Damin-Pernik, Bernadette Espana, Sebastien Lefebvre, Isabelle Fourel, Hervé Caruel, Etienne Benoit and Virginie Lattard
      Drug Metabolism and Disposition February 2017, 45 (2) 160-165; DOI: https://doi.org/10.1124/dmd.116.073791
  7. Le Marchand, Sylvain

    1. You have access
      Microvilli Morphology Can Affect Efflux Active P-Glycoprotein in Confluent MDCKII -hMDR1-NKI and Caco-2 Cell Monolayers
      Zhou Meng, Sylvain Le Marchand, Deep Agnani, Matthew Szapacs, Harma Ellens and Joe Bentz
      Drug Metabolism and Disposition February 2017, 45 (2) 145-151; DOI: https://doi.org/10.1124/dmd.116.072157
  8. Li, Daochuan

    1. Open Access
      Evaluation of a Novel Renewable Hepatic Cell Model for Prediction of Clinical CYP3A4 Induction Using a Correlation-Based Relative Induction Score Approach
      Rongjun Zuo, Feng Li, Sweta Parikh, Li Cao, Kirsten L. Cooper, Yulong Hong, Jin Liu, Ronald A. Faris, Daochuan Li and Hongbing Wang
      Drug Metabolism and Disposition February 2017, 45 (2) 198-207; DOI: https://doi.org/10.1124/dmd.116.072124
  9. Li, Feng

    1. Open Access
      Evaluation of a Novel Renewable Hepatic Cell Model for Prediction of Clinical CYP3A4 Induction Using a Correlation-Based Relative Induction Score Approach
      Rongjun Zuo, Feng Li, Sweta Parikh, Li Cao, Kirsten L. Cooper, Yulong Hong, Jin Liu, Ronald A. Faris, Daochuan Li and Hongbing Wang
      Drug Metabolism and Disposition February 2017, 45 (2) 198-207; DOI: https://doi.org/10.1124/dmd.116.072124
  10. Liang, Xiaomin

    1. You have access
      In Vivo Hepatic Enhancer Elements in the Human ABCG2 Locus
      Rachel J. Eclov, Mee J. Kim, Robin P. Smith, Xiaomin Liang, Nadav Ahituv and Deanna L. Kroetz
      Drug Metabolism and Disposition February 2017, 45 (2) 208-215; DOI: https://doi.org/10.1124/dmd.116.072033
  11. Liu, Jin

    1. Open Access
      Evaluation of a Novel Renewable Hepatic Cell Model for Prediction of Clinical CYP3A4 Induction Using a Correlation-Based Relative Induction Score Approach
      Rongjun Zuo, Feng Li, Sweta Parikh, Li Cao, Kirsten L. Cooper, Yulong Hong, Jin Liu, Ronald A. Faris, Daochuan Li and Hongbing Wang
      Drug Metabolism and Disposition February 2017, 45 (2) 198-207; DOI: https://doi.org/10.1124/dmd.116.072124
  12. Long, Amanda J.

    1. Open Access
      In Vitro and Clinical Evaluations of the Drug-Drug Interaction Potential of a Metabotropic Glutamate 2/3 Receptor Agonist Prodrug with Intestinal Peptide Transporter 1
      Y. Anne Pak, Amanda J. Long, William F. Annes, Jennifer W. Witcher, Mary Pat Knadler, Mosun A. Ayan-Oshodi, Malcolm I. Mitchell, Phillip Leese and Kathleen M. Hillgren
      Drug Metabolism and Disposition February 2017, 45 (2) 137-144; DOI: https://doi.org/10.1124/dmd.116.071118

M

  1. Mangas-Sanjuan, Victor

    1. You have access
      Target-Site Investigation for the Plasma Prolactin Response: Mechanism-Based Pharmacokinetic-Pharmacodynamic Analysis of Risperidone and Paliperidone in the Rat
      Shinji Shimizu, Sandra M. den Hoedt, Victor Mangas-Sanjuan, Sinziana Cristea, Jana K. Geuer, Dirk-Jan van den Berg, Robin Hartman, Francisco Bellanti and Elizabeth C. M. de Lange
      Drug Metabolism and Disposition February 2017, 45 (2) 152-159; DOI: https://doi.org/10.1124/dmd.116.072306
  2. Marx, Andreas

    1. Metabolism of the MEK1/2 Inhibitor Pimasertib Involves a Novel Conjugation with Phosphoethanolamine in Patients with Solid Tumors
      You have access
      Metabolism of the MEK1/2 Inhibitor Pimasertib Involves a Novel Conjugation with Phosphoethanolamine in Patients with Solid Tumors
      Holger Scheible, Friedrich Kraetzer, Andreas Marx, Andreas Johne and Elmar Wimmer
      Drug Metabolism and Disposition February 2017, 45 (2) 174-182; DOI: https://doi.org/10.1124/dmd.116.072934
  3. Mehrotra, Aanchal

    1. You have access
      Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants
      Mikael Boberg, Marc Vrana, Aanchal Mehrotra, Robin E. Pearce, Andrea Gaedigk, Deepak Kumar Bhatt, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition February 2017, 45 (2) 216-223; DOI: https://doi.org/10.1124/dmd.116.072652
  4. Meng, Zhou

    1. You have access
      Extrapolation of Elementary Rate Constants of P-glycoprotein–Mediated Transport from MDCKII-hMDR1-NKI to Caco-2 Cells
      Zhou Meng, Harma Ellens and Joe Bentz
      Drug Metabolism and Disposition February 2017, 45 (2) 190-197; DOI: https://doi.org/10.1124/dmd.116.072140
    2. You have access
      Microvilli Morphology Can Affect Efflux Active P-Glycoprotein in Confluent MDCKII -hMDR1-NKI and Caco-2 Cell Monolayers
      Zhou Meng, Sylvain Le Marchand, Deep Agnani, Matthew Szapacs, Harma Ellens and Joe Bentz
      Drug Metabolism and Disposition February 2017, 45 (2) 145-151; DOI: https://doi.org/10.1124/dmd.116.072157
  5. Mitchell, Malcolm I.

    1. Open Access
      In Vitro and Clinical Evaluations of the Drug-Drug Interaction Potential of a Metabotropic Glutamate 2/3 Receptor Agonist Prodrug with Intestinal Peptide Transporter 1
      Y. Anne Pak, Amanda J. Long, William F. Annes, Jennifer W. Witcher, Mary Pat Knadler, Mosun A. Ayan-Oshodi, Malcolm I. Mitchell, Phillip Leese and Kathleen M. Hillgren
      Drug Metabolism and Disposition February 2017, 45 (2) 137-144; DOI: https://doi.org/10.1124/dmd.116.071118

N

  1. Nakajima, Miki

    1. You have access
      Hepatic Dipeptidyl Peptidase-4 Controls Pharmacokinetics of Vildagliptin In Vivo
      Mitsutoshi Asakura, Tatsuki Fukami, Miki Nakajima, Hideaki Fujii, Koichiro Atsuda, Tomoo Itoh and Ryoichi Fujiwara
      Drug Metabolism and Disposition February 2017, 45 (2) 237-245; DOI: https://doi.org/10.1124/dmd.116.073866
  2. Nakanishi, Takeo

    1. You have access
      Comparative Evaluation of Dehydroepiandrosterone Sulfate Potential to Predict Hepatic Organic Anion Transporting Polypeptide Transporter-Based Drug-Drug Interactions
      Kei Nishizawa, Takeo Nakanishi and Ikumi Tamai
      Drug Metabolism and Disposition February 2017, 45 (2) 224-227; DOI: https://doi.org/10.1124/dmd.116.072355
  3. Nishizawa, Kei

    1. You have access
      Comparative Evaluation of Dehydroepiandrosterone Sulfate Potential to Predict Hepatic Organic Anion Transporting Polypeptide Transporter-Based Drug-Drug Interactions
      Kei Nishizawa, Takeo Nakanishi and Ikumi Tamai
      Drug Metabolism and Disposition February 2017, 45 (2) 224-227; DOI: https://doi.org/10.1124/dmd.116.072355

P

  1. Pak, Y. Anne

    1. Open Access
      In Vitro and Clinical Evaluations of the Drug-Drug Interaction Potential of a Metabotropic Glutamate 2/3 Receptor Agonist Prodrug with Intestinal Peptide Transporter 1
      Y. Anne Pak, Amanda J. Long, William F. Annes, Jennifer W. Witcher, Mary Pat Knadler, Mosun A. Ayan-Oshodi, Malcolm I. Mitchell, Phillip Leese and Kathleen M. Hillgren
      Drug Metabolism and Disposition February 2017, 45 (2) 137-144; DOI: https://doi.org/10.1124/dmd.116.071118
  2. Parikh, Sweta

    1. Open Access
      Evaluation of a Novel Renewable Hepatic Cell Model for Prediction of Clinical CYP3A4 Induction Using a Correlation-Based Relative Induction Score Approach
      Rongjun Zuo, Feng Li, Sweta Parikh, Li Cao, Kirsten L. Cooper, Yulong Hong, Jin Liu, Ronald A. Faris, Daochuan Li and Hongbing Wang
      Drug Metabolism and Disposition February 2017, 45 (2) 198-207; DOI: https://doi.org/10.1124/dmd.116.072124
  3. Pearce, Robin E.

    1. You have access
      Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants
      Mikael Boberg, Marc Vrana, Aanchal Mehrotra, Robin E. Pearce, Andrea Gaedigk, Deepak Kumar Bhatt, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition February 2017, 45 (2) 216-223; DOI: https://doi.org/10.1124/dmd.116.072652
  4. Phoa, Saffire S.K.S.

    1. You have access
      Impact of Organic Cation Transporters (OCT-SLC22A) on Differential Diagnosis of Intrahepatic Lesions
      Michele Visentin, Belle V. van Rosmalen, Christian Hiller, Matthanja Bieze, Lia Hofstetter, Joanne Verheij, Gerd A. Kullak-Ublick, Hermann Koepsell, Saffire S.K.S. Phoa, Ikumi Tamai, Roelof J. Bennink, Thomas M. van Gulik and Bruno Stieger
      Drug Metabolism and Disposition February 2017, 45 (2) 166-173; DOI: https://doi.org/10.1124/dmd.116.072371
  5. Prasad, Bhagwat

    1. You have access
      Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants
      Mikael Boberg, Marc Vrana, Aanchal Mehrotra, Robin E. Pearce, Andrea Gaedigk, Deepak Kumar Bhatt, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition February 2017, 45 (2) 216-223; DOI: https://doi.org/10.1124/dmd.116.072652

R

  1. Riddick, David S.

    1. You have access
      Role of Glucocorticoid Receptor and Pregnane X Receptor in Dexamethasone Induction of Rat Hepatic Aryl Hydrocarbon Receptor Nuclear Translocator and NADPH-Cytochrome P450 Oxidoreductase
      Sarah R. Hunter, Alex Vonk, Anne K. Mullen Grey and David S. Riddick
      Drug Metabolism and Disposition February 2017, 45 (2) 118-129; DOI: https://doi.org/10.1124/dmd.116.073833
  2. Rodrigues, A. David

    1. You have access
      Organic Anion Transporter 2: An Enigmatic Human Solute Carrier
      Hong Shen, Yurong Lai and A. David Rodrigues
      Drug Metabolism and Disposition February 2017, 45 (2) 228-236; DOI: https://doi.org/10.1124/dmd.116.072264

S

  1. Scheible, Holger

    1. Metabolism of the MEK1/2 Inhibitor Pimasertib Involves a Novel Conjugation with Phosphoethanolamine in Patients with Solid Tumors
      You have access
      Metabolism of the MEK1/2 Inhibitor Pimasertib Involves a Novel Conjugation with Phosphoethanolamine in Patients with Solid Tumors
      Holger Scheible, Friedrich Kraetzer, Andreas Marx, Andreas Johne and Elmar Wimmer
      Drug Metabolism and Disposition February 2017, 45 (2) 174-182; DOI: https://doi.org/10.1124/dmd.116.072934
  2. Shen, Hong

    1. You have access
      Organic Anion Transporter 2: An Enigmatic Human Solute Carrier
      Hong Shen, Yurong Lai and A. David Rodrigues
      Drug Metabolism and Disposition February 2017, 45 (2) 228-236; DOI: https://doi.org/10.1124/dmd.116.072264
  3. Shimizu, Shinji

    1. You have access
      Target-Site Investigation for the Plasma Prolactin Response: Mechanism-Based Pharmacokinetic-Pharmacodynamic Analysis of Risperidone and Paliperidone in the Rat
      Shinji Shimizu, Sandra M. den Hoedt, Victor Mangas-Sanjuan, Sinziana Cristea, Jana K. Geuer, Dirk-Jan van den Berg, Robin Hartman, Francisco Bellanti and Elizabeth C. M. de Lange
      Drug Metabolism and Disposition February 2017, 45 (2) 152-159; DOI: https://doi.org/10.1124/dmd.116.072306
  4. Siu, Y. Amy

    1. You have access
      Impact of Probe Substrate Selection on Cytochrome P450 Reaction Phenotyping Using the Relative Activity Factor
      Y. Amy Siu and W. George Lai
      Drug Metabolism and Disposition February 2017, 45 (2) 183-189; DOI: https://doi.org/10.1124/dmd.116.073510
  5. Smith, David E.

    1. You have access
      Species Differences in Human and Rodent PEPT2-Mediated Transport of Glycylsarcosine and Cefadroxil in Pichia Pastoris Transformants
      Feifeng Song, Yongjun Hu, Huidi Jiang and David E. Smith
      Drug Metabolism and Disposition February 2017, 45 (2) 130-136; DOI: https://doi.org/10.1124/dmd.116.073320
  6. Smith, Robin P.

    1. You have access
      In Vivo Hepatic Enhancer Elements in the Human ABCG2 Locus
      Rachel J. Eclov, Mee J. Kim, Robin P. Smith, Xiaomin Liang, Nadav Ahituv and Deanna L. Kroetz
      Drug Metabolism and Disposition February 2017, 45 (2) 208-215; DOI: https://doi.org/10.1124/dmd.116.072033
  7. Song, Feifeng

    1. You have access
      Species Differences in Human and Rodent PEPT2-Mediated Transport of Glycylsarcosine and Cefadroxil in Pichia Pastoris Transformants
      Feifeng Song, Yongjun Hu, Huidi Jiang and David E. Smith
      Drug Metabolism and Disposition February 2017, 45 (2) 130-136; DOI: https://doi.org/10.1124/dmd.116.073320
  8. Stieger, Bruno

    1. You have access
      Impact of Organic Cation Transporters (OCT-SLC22A) on Differential Diagnosis of Intrahepatic Lesions
      Michele Visentin, Belle V. van Rosmalen, Christian Hiller, Matthanja Bieze, Lia Hofstetter, Joanne Verheij, Gerd A. Kullak-Ublick, Hermann Koepsell, Saffire S.K.S. Phoa, Ikumi Tamai, Roelof J. Bennink, Thomas M. van Gulik and Bruno Stieger
      Drug Metabolism and Disposition February 2017, 45 (2) 166-173; DOI: https://doi.org/10.1124/dmd.116.072371
  9. Szapacs, Matthew

    1. You have access
      Microvilli Morphology Can Affect Efflux Active P-Glycoprotein in Confluent MDCKII -hMDR1-NKI and Caco-2 Cell Monolayers
      Zhou Meng, Sylvain Le Marchand, Deep Agnani, Matthew Szapacs, Harma Ellens and Joe Bentz
      Drug Metabolism and Disposition February 2017, 45 (2) 145-151; DOI: https://doi.org/10.1124/dmd.116.072157

T

  1. Tamai, Ikumi

    1. You have access
      Impact of Organic Cation Transporters (OCT-SLC22A) on Differential Diagnosis of Intrahepatic Lesions
      Michele Visentin, Belle V. van Rosmalen, Christian Hiller, Matthanja Bieze, Lia Hofstetter, Joanne Verheij, Gerd A. Kullak-Ublick, Hermann Koepsell, Saffire S.K.S. Phoa, Ikumi Tamai, Roelof J. Bennink, Thomas M. van Gulik and Bruno Stieger
      Drug Metabolism and Disposition February 2017, 45 (2) 166-173; DOI: https://doi.org/10.1124/dmd.116.072371
    2. You have access
      Comparative Evaluation of Dehydroepiandrosterone Sulfate Potential to Predict Hepatic Organic Anion Transporting Polypeptide Transporter-Based Drug-Drug Interactions
      Kei Nishizawa, Takeo Nakanishi and Ikumi Tamai
      Drug Metabolism and Disposition February 2017, 45 (2) 224-227; DOI: https://doi.org/10.1124/dmd.116.072355

V

  1. van den Berg, Dirk-Jan

    1. You have access
      Target-Site Investigation for the Plasma Prolactin Response: Mechanism-Based Pharmacokinetic-Pharmacodynamic Analysis of Risperidone and Paliperidone in the Rat
      Shinji Shimizu, Sandra M. den Hoedt, Victor Mangas-Sanjuan, Sinziana Cristea, Jana K. Geuer, Dirk-Jan van den Berg, Robin Hartman, Francisco Bellanti and Elizabeth C. M. de Lange
      Drug Metabolism and Disposition February 2017, 45 (2) 152-159; DOI: https://doi.org/10.1124/dmd.116.072306
  2. van Gulik, Thomas M.

    1. You have access
      Impact of Organic Cation Transporters (OCT-SLC22A) on Differential Diagnosis of Intrahepatic Lesions
      Michele Visentin, Belle V. van Rosmalen, Christian Hiller, Matthanja Bieze, Lia Hofstetter, Joanne Verheij, Gerd A. Kullak-Ublick, Hermann Koepsell, Saffire S.K.S. Phoa, Ikumi Tamai, Roelof J. Bennink, Thomas M. van Gulik and Bruno Stieger
      Drug Metabolism and Disposition February 2017, 45 (2) 166-173; DOI: https://doi.org/10.1124/dmd.116.072371
  3. van Rosmalen, Belle V.

    1. You have access
      Impact of Organic Cation Transporters (OCT-SLC22A) on Differential Diagnosis of Intrahepatic Lesions
      Michele Visentin, Belle V. van Rosmalen, Christian Hiller, Matthanja Bieze, Lia Hofstetter, Joanne Verheij, Gerd A. Kullak-Ublick, Hermann Koepsell, Saffire S.K.S. Phoa, Ikumi Tamai, Roelof J. Bennink, Thomas M. van Gulik and Bruno Stieger
      Drug Metabolism and Disposition February 2017, 45 (2) 166-173; DOI: https://doi.org/10.1124/dmd.116.072371
  4. Verheij, Joanne

    1. You have access
      Impact of Organic Cation Transporters (OCT-SLC22A) on Differential Diagnosis of Intrahepatic Lesions
      Michele Visentin, Belle V. van Rosmalen, Christian Hiller, Matthanja Bieze, Lia Hofstetter, Joanne Verheij, Gerd A. Kullak-Ublick, Hermann Koepsell, Saffire S.K.S. Phoa, Ikumi Tamai, Roelof J. Bennink, Thomas M. van Gulik and Bruno Stieger
      Drug Metabolism and Disposition February 2017, 45 (2) 166-173; DOI: https://doi.org/10.1124/dmd.116.072371
  5. Visentin, Michele

    1. You have access
      Impact of Organic Cation Transporters (OCT-SLC22A) on Differential Diagnosis of Intrahepatic Lesions
      Michele Visentin, Belle V. van Rosmalen, Christian Hiller, Matthanja Bieze, Lia Hofstetter, Joanne Verheij, Gerd A. Kullak-Ublick, Hermann Koepsell, Saffire S.K.S. Phoa, Ikumi Tamai, Roelof J. Bennink, Thomas M. van Gulik and Bruno Stieger
      Drug Metabolism and Disposition February 2017, 45 (2) 166-173; DOI: https://doi.org/10.1124/dmd.116.072371
  6. Vonk, Alex

    1. You have access
      Role of Glucocorticoid Receptor and Pregnane X Receptor in Dexamethasone Induction of Rat Hepatic Aryl Hydrocarbon Receptor Nuclear Translocator and NADPH-Cytochrome P450 Oxidoreductase
      Sarah R. Hunter, Alex Vonk, Anne K. Mullen Grey and David S. Riddick
      Drug Metabolism and Disposition February 2017, 45 (2) 118-129; DOI: https://doi.org/10.1124/dmd.116.073833
  7. Vrana, Marc

    1. You have access
      Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants
      Mikael Boberg, Marc Vrana, Aanchal Mehrotra, Robin E. Pearce, Andrea Gaedigk, Deepak Kumar Bhatt, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition February 2017, 45 (2) 216-223; DOI: https://doi.org/10.1124/dmd.116.072652

W

  1. Wang, Hongbing

    1. Open Access
      Evaluation of a Novel Renewable Hepatic Cell Model for Prediction of Clinical CYP3A4 Induction Using a Correlation-Based Relative Induction Score Approach
      Rongjun Zuo, Feng Li, Sweta Parikh, Li Cao, Kirsten L. Cooper, Yulong Hong, Jin Liu, Ronald A. Faris, Daochuan Li and Hongbing Wang
      Drug Metabolism and Disposition February 2017, 45 (2) 198-207; DOI: https://doi.org/10.1124/dmd.116.072124
  2. Wimmer, Elmar

    1. Metabolism of the MEK1/2 Inhibitor Pimasertib Involves a Novel Conjugation with Phosphoethanolamine in Patients with Solid Tumors
      You have access
      Metabolism of the MEK1/2 Inhibitor Pimasertib Involves a Novel Conjugation with Phosphoethanolamine in Patients with Solid Tumors
      Holger Scheible, Friedrich Kraetzer, Andreas Marx, Andreas Johne and Elmar Wimmer
      Drug Metabolism and Disposition February 2017, 45 (2) 174-182; DOI: https://doi.org/10.1124/dmd.116.072934
  3. Witcher, Jennifer W.

    1. Open Access
      In Vitro and Clinical Evaluations of the Drug-Drug Interaction Potential of a Metabotropic Glutamate 2/3 Receptor Agonist Prodrug with Intestinal Peptide Transporter 1
      Y. Anne Pak, Amanda J. Long, William F. Annes, Jennifer W. Witcher, Mary Pat Knadler, Mosun A. Ayan-Oshodi, Malcolm I. Mitchell, Phillip Leese and Kathleen M. Hillgren
      Drug Metabolism and Disposition February 2017, 45 (2) 137-144; DOI: https://doi.org/10.1124/dmd.116.071118

Z

  1. Zuo, Rongjun

    1. Open Access
      Evaluation of a Novel Renewable Hepatic Cell Model for Prediction of Clinical CYP3A4 Induction Using a Correlation-Based Relative Induction Score Approach
      Rongjun Zuo, Feng Li, Sweta Parikh, Li Cao, Kirsten L. Cooper, Yulong Hong, Jin Liu, Ronald A. Faris, Daochuan Li and Hongbing Wang
      Drug Metabolism and Disposition February 2017, 45 (2) 198-207; DOI: https://doi.org/10.1124/dmd.116.072124
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Drug Metabolism and Disposition: 45 (2)
Drug Metabolism and Disposition
Vol. 45, Issue 2
1 Feb 2017
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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