Research ArticleArticle
Application of Static Modeling in the Prediction of In Vivo Drug–Drug Interactions between Rivaroxaban and Antiarrhythmic Agents Based on In Vitro Inhibition Studies
Eleanor Jing Yi Cheong, Janice Jia Ni Goh, Yanjun Hong, Gopalakrishnan Venkatesan, Yuanjie Liu, Gigi Ngar Chee Chiu, Pipin Kojodjojo and Eric Chun Yong Chan
Drug Metabolism and Disposition March 2017, 45 (3) 260-268; DOI: https://doi.org/10.1124/dmd.116.073890
Eleanor Jing Yi Cheong
Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore (E.J.Y.C., J.J.N.G., Y.H., G.V., Y.L., G.N.C.C., E.C.Y.C.); Department of Chemistry, Faculty of Science, Hong Kong Baptist University, Ho Sin Hang Campus, Hong Kong (Y.H.); Department of Cardiology and Cardiac Electrophysiology, National University Heart Centre, Singapore (P.K.); and Singapore Institute for Clinical Sciences, Brenner Centre for Molecular Medicine, Singapore (E.C.Y.C.)
Janice Jia Ni Goh
Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore (E.J.Y.C., J.J.N.G., Y.H., G.V., Y.L., G.N.C.C., E.C.Y.C.); Department of Chemistry, Faculty of Science, Hong Kong Baptist University, Ho Sin Hang Campus, Hong Kong (Y.H.); Department of Cardiology and Cardiac Electrophysiology, National University Heart Centre, Singapore (P.K.); and Singapore Institute for Clinical Sciences, Brenner Centre for Molecular Medicine, Singapore (E.C.Y.C.)
Yanjun Hong
Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore (E.J.Y.C., J.J.N.G., Y.H., G.V., Y.L., G.N.C.C., E.C.Y.C.); Department of Chemistry, Faculty of Science, Hong Kong Baptist University, Ho Sin Hang Campus, Hong Kong (Y.H.); Department of Cardiology and Cardiac Electrophysiology, National University Heart Centre, Singapore (P.K.); and Singapore Institute for Clinical Sciences, Brenner Centre for Molecular Medicine, Singapore (E.C.Y.C.)
Gopalakrishnan Venkatesan
Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore (E.J.Y.C., J.J.N.G., Y.H., G.V., Y.L., G.N.C.C., E.C.Y.C.); Department of Chemistry, Faculty of Science, Hong Kong Baptist University, Ho Sin Hang Campus, Hong Kong (Y.H.); Department of Cardiology and Cardiac Electrophysiology, National University Heart Centre, Singapore (P.K.); and Singapore Institute for Clinical Sciences, Brenner Centre for Molecular Medicine, Singapore (E.C.Y.C.)
Yuanjie Liu
Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore (E.J.Y.C., J.J.N.G., Y.H., G.V., Y.L., G.N.C.C., E.C.Y.C.); Department of Chemistry, Faculty of Science, Hong Kong Baptist University, Ho Sin Hang Campus, Hong Kong (Y.H.); Department of Cardiology and Cardiac Electrophysiology, National University Heart Centre, Singapore (P.K.); and Singapore Institute for Clinical Sciences, Brenner Centre for Molecular Medicine, Singapore (E.C.Y.C.)
Gigi Ngar Chee Chiu
Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore (E.J.Y.C., J.J.N.G., Y.H., G.V., Y.L., G.N.C.C., E.C.Y.C.); Department of Chemistry, Faculty of Science, Hong Kong Baptist University, Ho Sin Hang Campus, Hong Kong (Y.H.); Department of Cardiology and Cardiac Electrophysiology, National University Heart Centre, Singapore (P.K.); and Singapore Institute for Clinical Sciences, Brenner Centre for Molecular Medicine, Singapore (E.C.Y.C.)
Pipin Kojodjojo
Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore (E.J.Y.C., J.J.N.G., Y.H., G.V., Y.L., G.N.C.C., E.C.Y.C.); Department of Chemistry, Faculty of Science, Hong Kong Baptist University, Ho Sin Hang Campus, Hong Kong (Y.H.); Department of Cardiology and Cardiac Electrophysiology, National University Heart Centre, Singapore (P.K.); and Singapore Institute for Clinical Sciences, Brenner Centre for Molecular Medicine, Singapore (E.C.Y.C.)
Eric Chun Yong Chan
Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore (E.J.Y.C., J.J.N.G., Y.H., G.V., Y.L., G.N.C.C., E.C.Y.C.); Department of Chemistry, Faculty of Science, Hong Kong Baptist University, Ho Sin Hang Campus, Hong Kong (Y.H.); Department of Cardiology and Cardiac Electrophysiology, National University Heart Centre, Singapore (P.K.); and Singapore Institute for Clinical Sciences, Brenner Centre for Molecular Medicine, Singapore (E.C.Y.C.)
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Research ArticleArticle
Interactions between Rivaroxaban and Antiarrhythmic Agents
Eleanor Jing Yi Cheong, Janice Jia Ni Goh, Yanjun Hong, Gopalakrishnan Venkatesan, Yuanjie Liu, Gigi Ngar Chee Chiu, Pipin Kojodjojo and Eric Chun Yong Chan
Drug Metabolism and Disposition March 1, 2017, 45 (3) 260-268; DOI: https://doi.org/10.1124/dmd.116.073890
Research ArticleArticle
Interactions between Rivaroxaban and Antiarrhythmic Agents
Eleanor Jing Yi Cheong, Janice Jia Ni Goh, Yanjun Hong, Gopalakrishnan Venkatesan, Yuanjie Liu, Gigi Ngar Chee Chiu, Pipin Kojodjojo and Eric Chun Yong Chan
Drug Metabolism and Disposition March 1, 2017, 45 (3) 260-268; DOI: https://doi.org/10.1124/dmd.116.073890
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