Table of Contents

Articles

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  Cholic Acid Feeding Leads to Increased CYP2D6 Expression in CYP2D6-Humanized Mice

  Xian Pan, Rebecca Kent, Kyoung-Jae Won and Hyunyoung Jeong

  Drug Metabolism and Disposition April 2017, 45 (4) 346-352; DOI: https://doi.org/10.1124/dmd.116.074013
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  Regional Expression Levels of Drug Transporters and Metabolizing Enzymes along the Pig and Human Intestinal Tract and Comparison with Caco-2 Cells

  Stefan F.C. Vaessen, Marola M.H. van Lipzig, Raymond H.H. Pieters, Cyrille A.M. Krul, Heleen M. Wortelboer and Evita van de Steeg

  Drug Metabolism and Disposition April 2017, 45 (4) 353-360; DOI: https://doi.org/10.1124/dmd.116.072231
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  A Physiologically-Based Pharmacokinetic Modeling Approach To Predict Drug–Drug Interactions of Sonidegib (LDE225) with Perpetrators of CYP3A in Cancer Patients

  Heidi J. Einolf, Jocelyn Zhou, Christina Won, Lai Wang and Sam Rebello

  Drug Metabolism and Disposition April 2017, 45 (4) 361-374; DOI: https://doi.org/10.1124/dmd.116.073585
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  Application of Physiologically Based Pharmacokinetic Modeling to the Understanding of Bosutinib Pharmacokinetics: Prediction of Drug–Drug and Drug–Disease Interactions

  Chiho Ono, Poe-Hirr Hsyu, Richat Abbas, Cho-Ming Loi and Shinji Yamazaki

  Drug Metabolism and Disposition April 2017, 45 (4) 390-398; DOI: https://doi.org/10.1124/dmd.116.074450
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  Comparison between Radioanalysis and ¹⁹F Nuclear Magnetic Resonance Spectroscopy in the Determination of Mass Balance, Metabolism, and Distribution of Pefloxacin

  Haitao Hu, Kishore Kumar Katyayan, Boris A. Czeskis, Everett J. Perkins and Palaniappan Kulanthaivel

  Drug Metabolism and Disposition April 2017, 45 (4) 399-408; DOI: https://doi.org/10.1124/dmd.116.073809
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  Quantitative Prediction of Human Renal Clearance and Drug-Drug Interactions of Organic Anion Transporter Substrates Using In Vitro Transport Data: A Relative Activity Factor Approach

  Sumathy Mathialagan, Mary A. Piotrowski, David A. Tess, Bo Feng, John Litchfield and Manthena V. Varma

  Drug Metabolism and Disposition April 2017, 45 (4) 409-417; DOI: https://doi.org/10.1124/dmd.116.074294
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  Transcriptional, Functional, and Mechanistic Comparisons of Stem Cell–Derived Hepatocytes, HepaRG Cells, and Three-Dimensional Human Hepatocyte Spheroids as Predictive In Vitro Systems for Drug-Induced Liver Injury

  Catherine C. Bell, Volker M. Lauschke, Sabine U. Vorrink, Henrik Palmgren, Rodger Duffin, Tommy B. Andersson and Magnus Ingelman-Sundberg

  Drug Metabolism and Disposition April 2017, 45 (4) 419-429; DOI: https://doi.org/10.1124/dmd.116.074369