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Drug Metabolism & Disposition

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Table of Contents

April 01, 2017; Volume 45,Issue 4

Minireview

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    Alternative Splicing in the Cytochrome P450 Superfamily Expands Protein Diversity to Augment Gene Function and Redirect Human Drug Metabolism
    Andrew J. Annalora, Craig B. Marcus and Patrick L. Iversen
    Drug Metabolism and Disposition April 2017, 45 (4) 375-389; DOI: https://doi.org/10.1124/dmd.116.073254

Articles

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    Cholic Acid Feeding Leads to Increased CYP2D6 Expression in CYP2D6-Humanized Mice
    Xian Pan, Rebecca Kent, Kyoung-Jae Won and Hyunyoung Jeong
    Drug Metabolism and Disposition April 2017, 45 (4) 346-352; DOI: https://doi.org/10.1124/dmd.116.074013
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    Regional Expression Levels of Drug Transporters and Metabolizing Enzymes along the Pig and Human Intestinal Tract and Comparison with Caco-2 Cells
    Stefan F.C. Vaessen, Marola M.H. van Lipzig, Raymond H.H. Pieters, Cyrille A.M. Krul, Heleen M. Wortelboer and Evita van de Steeg
    Drug Metabolism and Disposition April 2017, 45 (4) 353-360; DOI: https://doi.org/10.1124/dmd.116.072231
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    A Physiologically-Based Pharmacokinetic Modeling Approach To Predict Drug–Drug Interactions of Sonidegib (LDE225) with Perpetrators of CYP3A in Cancer Patients
    Heidi J. Einolf, Jocelyn Zhou, Christina Won, Lai Wang and Sam Rebello
    Drug Metabolism and Disposition April 2017, 45 (4) 361-374; DOI: https://doi.org/10.1124/dmd.116.073585
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    Application of Physiologically Based Pharmacokinetic Modeling to the Understanding of Bosutinib Pharmacokinetics: Prediction of Drug–Drug and Drug–Disease Interactions
    Chiho Ono, Poe-Hirr Hsyu, Richat Abbas, Cho-Ming Loi and Shinji Yamazaki
    Drug Metabolism and Disposition April 2017, 45 (4) 390-398; DOI: https://doi.org/10.1124/dmd.116.074450
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    Comparison between Radioanalysis and 19F Nuclear Magnetic Resonance Spectroscopy in the Determination of Mass Balance, Metabolism, and Distribution of Pefloxacin
    Haitao Hu, Kishore Kumar Katyayan, Boris A. Czeskis, Everett J. Perkins and Palaniappan Kulanthaivel
    Drug Metabolism and Disposition April 2017, 45 (4) 399-408; DOI: https://doi.org/10.1124/dmd.116.073809
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    Quantitative Prediction of Human Renal Clearance and Drug-Drug Interactions of Organic Anion Transporter Substrates Using In Vitro Transport Data: A Relative Activity Factor Approach
    Sumathy Mathialagan, Mary A. Piotrowski, David A. Tess, Bo Feng, John Litchfield and Manthena V. Varma
    Drug Metabolism and Disposition April 2017, 45 (4) 409-417; DOI: https://doi.org/10.1124/dmd.116.074294
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    Transcriptional, Functional, and Mechanistic Comparisons of Stem Cell–Derived Hepatocytes, HepaRG Cells, and Three-Dimensional Human Hepatocyte Spheroids as Predictive In Vitro Systems for Drug-Induced Liver Injury
    Catherine C. Bell, Volker M. Lauschke, Sabine U. Vorrink, Henrik Palmgren, Rodger Duffin, Tommy B. Andersson and Magnus Ingelman-Sundberg
    Drug Metabolism and Disposition April 2017, 45 (4) 419-429; DOI: https://doi.org/10.1124/dmd.116.074369

Short Communication

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    Intrinsic Clearance Assay Incubational Binding: A Method Comparison
    Sofia Chen, Luna Prieto Garcia, Fredrik Bergström, Pär Nordell and Ken Grime
    Drug Metabolism and Disposition April 2017, 45 (4) 342-345; DOI: https://doi.org/10.1124/dmd.116.074138

Erratum

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    Correction to “p38 MAP Kinase Links CAR Activation and Inactivation in the Nucleus via Phosphorylation at Threonine 38 s”
    Drug Metabolism and Disposition April 2017, 45 (4) 418; DOI: https://doi.org/10.1124/dmd.115.070235err
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Drug Metabolism and Disposition: 45 (4)
Drug Metabolism and Disposition
Vol. 45, Issue 4
1 Apr 2017
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