Advertisement

Index by author

May 01, 2017; Volume 45,Issue 5

A

  1. Almon, Richard R.

    1. Effect of Disease-Related Changes in Plasma Albumin on the Pharmacokinetics of Naproxen in Male and Female Arthritic Rats
      Xiaonan Li, Debra C. DuBois, Richard R. Almon and William J. Jusko
      Drug Metabolism and Disposition May 2017, 45 (5) 476-483; DOI: https://doi.org/10.1124/dmd.116.074500
    2. Modeling Sex Differences in Pharmacokinetics, Pharmacodynamics, and Disease Progression Effects of Naproxen in Rats with Collagen-Induced Arthritis
      Xiaonan Li, Debra C. DuBois, Richard R. Almon and William J. Jusko
      Drug Metabolism and Disposition May 2017, 45 (5) 484-491; DOI: https://doi.org/10.1124/dmd.116.074526

  2. Argikar, Upendra A.

    1. Implications for Metabolite Quantification by Mass Spectrometry in the Absence of Authentic Standards
      Panos Hatsis, Nigel J. Waters and Upendra A. Argikar
      Drug Metabolism and Disposition May 2017, 45 (5) 492-496; DOI: https://doi.org/10.1124/dmd.117.075259

  3. Atkinson, Karen

    1. Novel Method to Predict In Vivo Liver-to-Plasma Kpuu for OATP Substrates Using Suspension Hepatocytes
      Keith Riccardi, Jian Lin, Zhenhong Li, Mark Niosi, Sangwoo Ryu, Wenyi Hua, Karen Atkinson, Rachel E. Kosa, John Litchfield and Li Di
      Drug Metabolism and Disposition May 2017, 45 (5) 576-580; DOI: https://doi.org/10.1124/dmd.116.074575

B

  1. Billington, Sarah

    1. Open Access
      Microsomal and Cytosolic Scaling Factors in Dog and Human Kidney Cortex and Application for In Vitro-In Vivo Extrapolation of Renal Metabolic Clearance
      Daniel Scotcher, Sarah Billington, Jay Brown, Christopher R. Jones, Colin D. A. Brown, Amin Rostami-Hodjegan and Aleksandra Galetin
      Drug Metabolism and Disposition May 2017, 45 (5) 556-568; DOI: https://doi.org/10.1124/dmd.117.075242

  2. Brown, Colin D. A.

    1. Open Access
      Microsomal and Cytosolic Scaling Factors in Dog and Human Kidney Cortex and Application for In Vitro-In Vivo Extrapolation of Renal Metabolic Clearance
      Daniel Scotcher, Sarah Billington, Jay Brown, Christopher R. Jones, Colin D. A. Brown, Amin Rostami-Hodjegan and Aleksandra Galetin
      Drug Metabolism and Disposition May 2017, 45 (5) 556-568; DOI: https://doi.org/10.1124/dmd.117.075242

  3. Brown, Jay

    1. Open Access
      Microsomal and Cytosolic Scaling Factors in Dog and Human Kidney Cortex and Application for In Vitro-In Vivo Extrapolation of Renal Metabolic Clearance
      Daniel Scotcher, Sarah Billington, Jay Brown, Christopher R. Jones, Colin D. A. Brown, Amin Rostami-Hodjegan and Aleksandra Galetin
      Drug Metabolism and Disposition May 2017, 45 (5) 556-568; DOI: https://doi.org/10.1124/dmd.117.075242

  4. Buckbinder, Leonard

    1. Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome
      Jennifer Q. Dong, James R. Gosset, Odette A. Fahmi, Zhiwu Lin, Jeffrey R. Chabot, Steven G. Terra, Vu Le, Kristin Chidsey, Parya Nouri, Albert Kim, Leonard Buckbinder and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2017, 45 (5) 501-511; DOI: https://doi.org/10.1124/dmd.116.074476

C

  1. Camenisch, Gian

    1. Assessing the Risk of Drug-Induced Cholestasis Using Unbound Intrahepatic Concentrations
      Julia Riede, Birk Poller, Jörg Huwyler and Gian Camenisch
      Drug Metabolism and Disposition May 2017, 45 (5) 523-531; DOI: https://doi.org/10.1124/dmd.116.074179

  2. Chabot, Jeffrey R.

    1. Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome
      Jennifer Q. Dong, James R. Gosset, Odette A. Fahmi, Zhiwu Lin, Jeffrey R. Chabot, Steven G. Terra, Vu Le, Kristin Chidsey, Parya Nouri, Albert Kim, Leonard Buckbinder and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2017, 45 (5) 501-511; DOI: https://doi.org/10.1124/dmd.116.074476

  3. Chen, Qingfang

    1. Correlation between Membrane Protein Expression Levels and Transcellular Transport Activity for Breast Cancer Resistance Protein
      Houfu Liu, Liang Huang, Yi Li, Tingting Fu, Xueying Sun, Yan-Yan Zhang, Ruina Gao, Qingfang Chen, Wandong Zhang, Jasminder Sahi, Scott Summerfield and Kelly Dong
      Drug Metabolism and Disposition May 2017, 45 (5) 449-456; DOI: https://doi.org/10.1124/dmd.116.074245

  4. Chen, Xiaoyan

    1. Nimesulide and 4′-Hydroxynimesulide as Bile Acid Transporters Inhibitors Are Contributory Factors for Drug-Induced Cholestasis
      Lei Zhou, Xiaoyan Pang, Jingfang Jiang, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition May 2017, 45 (5) 441-448; DOI: https://doi.org/10.1124/dmd.116.074104

  5. Chen, Yuan

    1. Novel Mechanism of Decyanation of GDC-0425 by Cytochrome P450
      Ryan H. Takahashi, Jason S. Halladay, Michael Siu, Yuan Chen, Cornelis E. C. A. Hop, S. Cyrus Khojasteh and Shuguang Ma
      Drug Metabolism and Disposition May 2017, 45 (5) 430-440; DOI: https://doi.org/10.1124/dmd.116.074336

  6. Chidsey, Kristin

    1. Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome
      Jennifer Q. Dong, James R. Gosset, Odette A. Fahmi, Zhiwu Lin, Jeffrey R. Chabot, Steven G. Terra, Vu Le, Kristin Chidsey, Parya Nouri, Albert Kim, Leonard Buckbinder and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2017, 45 (5) 501-511; DOI: https://doi.org/10.1124/dmd.116.074476

  7. Clewell, Harvey J.

    1. Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages
      Gina Song, Xueying Sun, Ronald N. Hines, D. Gail McCarver, Brian G. Lake, Thomas G. Osimitz, Moire R. Creek, Harvey J. Clewell and Miyoung Yoon
      Drug Metabolism and Disposition May 2017, 45 (5) 468-475; DOI: https://doi.org/10.1124/dmd.116.074583

  8. Creek, Moire R.

    1. Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages
      Gina Song, Xueying Sun, Ronald N. Hines, D. Gail McCarver, Brian G. Lake, Thomas G. Osimitz, Moire R. Creek, Harvey J. Clewell and Miyoung Yoon
      Drug Metabolism and Disposition May 2017, 45 (5) 468-475; DOI: https://doi.org/10.1124/dmd.116.074583

D

  1. Di, Li

    1. Novel Method to Predict In Vivo Liver-to-Plasma Kpuu for OATP Substrates Using Suspension Hepatocytes
      Keith Riccardi, Jian Lin, Zhenhong Li, Mark Niosi, Sangwoo Ryu, Wenyi Hua, Karen Atkinson, Rachel E. Kosa, John Litchfield and Li Di
      Drug Metabolism and Disposition May 2017, 45 (5) 576-580; DOI: https://doi.org/10.1124/dmd.116.074575

  2. Dong, Jennifer Q.

    1. Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome
      Jennifer Q. Dong, James R. Gosset, Odette A. Fahmi, Zhiwu Lin, Jeffrey R. Chabot, Steven G. Terra, Vu Le, Kristin Chidsey, Parya Nouri, Albert Kim, Leonard Buckbinder and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2017, 45 (5) 501-511; DOI: https://doi.org/10.1124/dmd.116.074476

  3. Dong, Kelly

    1. Correlation between Membrane Protein Expression Levels and Transcellular Transport Activity for Breast Cancer Resistance Protein
      Houfu Liu, Liang Huang, Yi Li, Tingting Fu, Xueying Sun, Yan-Yan Zhang, Ruina Gao, Qingfang Chen, Wandong Zhang, Jasminder Sahi, Scott Summerfield and Kelly Dong
      Drug Metabolism and Disposition May 2017, 45 (5) 449-456; DOI: https://doi.org/10.1124/dmd.116.074245

  4. DuBois, Debra C.

    1. Effect of Disease-Related Changes in Plasma Albumin on the Pharmacokinetics of Naproxen in Male and Female Arthritic Rats
      Xiaonan Li, Debra C. DuBois, Richard R. Almon and William J. Jusko
      Drug Metabolism and Disposition May 2017, 45 (5) 476-483; DOI: https://doi.org/10.1124/dmd.116.074500
    2. Modeling Sex Differences in Pharmacokinetics, Pharmacodynamics, and Disease Progression Effects of Naproxen in Rats with Collagen-Induced Arthritis
      Xiaonan Li, Debra C. DuBois, Richard R. Almon and William J. Jusko
      Drug Metabolism and Disposition May 2017, 45 (5) 484-491; DOI: https://doi.org/10.1124/dmd.116.074526

F

  1. Fahmi, Odette A.

    1. Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome
      Jennifer Q. Dong, James R. Gosset, Odette A. Fahmi, Zhiwu Lin, Jeffrey R. Chabot, Steven G. Terra, Vu Le, Kristin Chidsey, Parya Nouri, Albert Kim, Leonard Buckbinder and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2017, 45 (5) 501-511; DOI: https://doi.org/10.1124/dmd.116.074476

  2. Fu, Tingting

    1. Correlation between Membrane Protein Expression Levels and Transcellular Transport Activity for Breast Cancer Resistance Protein
      Houfu Liu, Liang Huang, Yi Li, Tingting Fu, Xueying Sun, Yan-Yan Zhang, Ruina Gao, Qingfang Chen, Wandong Zhang, Jasminder Sahi, Scott Summerfield and Kelly Dong
      Drug Metabolism and Disposition May 2017, 45 (5) 449-456; DOI: https://doi.org/10.1124/dmd.116.074245

G

  1. Galetin, Aleksandra

    1. Open Access
      Microsomal and Cytosolic Scaling Factors in Dog and Human Kidney Cortex and Application for In Vitro-In Vivo Extrapolation of Renal Metabolic Clearance
      Daniel Scotcher, Sarah Billington, Jay Brown, Christopher R. Jones, Colin D. A. Brown, Amin Rostami-Hodjegan and Aleksandra Galetin
      Drug Metabolism and Disposition May 2017, 45 (5) 556-568; DOI: https://doi.org/10.1124/dmd.117.075242

  2. Gao, Ruina

    1. Correlation between Membrane Protein Expression Levels and Transcellular Transport Activity for Breast Cancer Resistance Protein
      Houfu Liu, Liang Huang, Yi Li, Tingting Fu, Xueying Sun, Yan-Yan Zhang, Ruina Gao, Qingfang Chen, Wandong Zhang, Jasminder Sahi, Scott Summerfield and Kelly Dong
      Drug Metabolism and Disposition May 2017, 45 (5) 449-456; DOI: https://doi.org/10.1124/dmd.116.074245

  3. Gatlik, Ewa

    1. Midostaurin, a Novel Protein Kinase Inhibitor for the Treatment of Acute Myelogenous Leukemia: Insights from Human Absorption, Metabolism, and Excretion Studies of a BDDCS II Drug
      Handan He, Phi Tran, Helen Gu, Vivienne Tedesco, Jin Zhang, Wen Lin, Ewa Gatlik, Kai Klein and Tycho Heimbach
      Drug Metabolism and Disposition May 2017, 45 (5) 540-555; DOI: https://doi.org/10.1124/dmd.116.072744

  4. Gerber, Jacobus P.

    1. Effect of Garlic, Gingko, and St. John’s Wort Extracts on the Pharmacokinetics of Fexofenadine: A Mechanistic Study
      Jasmina Turkanovic, Michael B. Ward, Jacobus P. Gerber and Robert W. Milne
      Drug Metabolism and Disposition May 2017, 45 (5) 569-575; DOI: https://doi.org/10.1124/dmd.116.073528

  5. Gosset, James R.

    1. Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome
      Jennifer Q. Dong, James R. Gosset, Odette A. Fahmi, Zhiwu Lin, Jeffrey R. Chabot, Steven G. Terra, Vu Le, Kristin Chidsey, Parya Nouri, Albert Kim, Leonard Buckbinder and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2017, 45 (5) 501-511; DOI: https://doi.org/10.1124/dmd.116.074476

  6. Gu, Helen

    1. Midostaurin, a Novel Protein Kinase Inhibitor for the Treatment of Acute Myelogenous Leukemia: Insights from Human Absorption, Metabolism, and Excretion Studies of a BDDCS II Drug
      Handan He, Phi Tran, Helen Gu, Vivienne Tedesco, Jin Zhang, Wen Lin, Ewa Gatlik, Kai Klein and Tycho Heimbach
      Drug Metabolism and Disposition May 2017, 45 (5) 540-555; DOI: https://doi.org/10.1124/dmd.116.072744

H

  1. Halladay, Jason S.

    1. Novel Mechanism of Decyanation of GDC-0425 by Cytochrome P450
      Ryan H. Takahashi, Jason S. Halladay, Michael Siu, Yuan Chen, Cornelis E. C. A. Hop, S. Cyrus Khojasteh and Shuguang Ma
      Drug Metabolism and Disposition May 2017, 45 (5) 430-440; DOI: https://doi.org/10.1124/dmd.116.074336

  2. Hatsis, Panos

    1. Implications for Metabolite Quantification by Mass Spectrometry in the Absence of Authentic Standards
      Panos Hatsis, Nigel J. Waters and Upendra A. Argikar
      Drug Metabolism and Disposition May 2017, 45 (5) 492-496; DOI: https://doi.org/10.1124/dmd.117.075259

  3. He, Handan

    1. Midostaurin, a Novel Protein Kinase Inhibitor for the Treatment of Acute Myelogenous Leukemia: Insights from Human Absorption, Metabolism, and Excretion Studies of a BDDCS II Drug
      Handan He, Phi Tran, Helen Gu, Vivienne Tedesco, Jin Zhang, Wen Lin, Ewa Gatlik, Kai Klein and Tycho Heimbach
      Drug Metabolism and Disposition May 2017, 45 (5) 540-555; DOI: https://doi.org/10.1124/dmd.116.072744

  4. Heimbach, Tycho

    1. Midostaurin, a Novel Protein Kinase Inhibitor for the Treatment of Acute Myelogenous Leukemia: Insights from Human Absorption, Metabolism, and Excretion Studies of a BDDCS II Drug
      Handan He, Phi Tran, Helen Gu, Vivienne Tedesco, Jin Zhang, Wen Lin, Ewa Gatlik, Kai Klein and Tycho Heimbach
      Drug Metabolism and Disposition May 2017, 45 (5) 540-555; DOI: https://doi.org/10.1124/dmd.116.072744

  5. Hines, Ronald N.

    1. Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages
      Gina Song, Xueying Sun, Ronald N. Hines, D. Gail McCarver, Brian G. Lake, Thomas G. Osimitz, Moire R. Creek, Harvey J. Clewell and Miyoung Yoon
      Drug Metabolism and Disposition May 2017, 45 (5) 468-475; DOI: https://doi.org/10.1124/dmd.116.074583

  6. Hop, Cornelis E. C. A.

    1. Novel Mechanism of Decyanation of GDC-0425 by Cytochrome P450
      Ryan H. Takahashi, Jason S. Halladay, Michael Siu, Yuan Chen, Cornelis E. C. A. Hop, S. Cyrus Khojasteh and Shuguang Ma
      Drug Metabolism and Disposition May 2017, 45 (5) 430-440; DOI: https://doi.org/10.1124/dmd.116.074336

  7. Hua, Wenyi

    1. Novel Method to Predict In Vivo Liver-to-Plasma Kpuu for OATP Substrates Using Suspension Hepatocytes
      Keith Riccardi, Jian Lin, Zhenhong Li, Mark Niosi, Sangwoo Ryu, Wenyi Hua, Karen Atkinson, Rachel E. Kosa, John Litchfield and Li Di
      Drug Metabolism and Disposition May 2017, 45 (5) 576-580; DOI: https://doi.org/10.1124/dmd.116.074575

  8. Huang, Liang

    1. Correlation between Membrane Protein Expression Levels and Transcellular Transport Activity for Breast Cancer Resistance Protein
      Houfu Liu, Liang Huang, Yi Li, Tingting Fu, Xueying Sun, Yan-Yan Zhang, Ruina Gao, Qingfang Chen, Wandong Zhang, Jasminder Sahi, Scott Summerfield and Kelly Dong
      Drug Metabolism and Disposition May 2017, 45 (5) 449-456; DOI: https://doi.org/10.1124/dmd.116.074245

  9. Huwyler, Jörg

    1. Assessing the Risk of Drug-Induced Cholestasis Using Unbound Intrahepatic Concentrations
      Julia Riede, Birk Poller, Jörg Huwyler and Gian Camenisch
      Drug Metabolism and Disposition May 2017, 45 (5) 523-531; DOI: https://doi.org/10.1124/dmd.116.074179

I

  1. Inoue, Takashi

    1. Marmoset Cytochrome P450 3A4 Ortholog Expressed in Liver and Small-Intestine Tissues Efficiently Metabolizes Midazolam, Alprazolam, Nifedipine, and Testosterone
      Shotaro Uehara, Yasuhiro Uno, Kazuyuki Nakanishi, Sakura Ishii, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2017, 45 (5) 457-467; DOI: https://doi.org/10.1124/dmd.116.074898
    2. Marmoset Flavin-Containing Monooxygenase 3 in the Liver Is a Major Benzydamine and Sulindac Sulfide Oxygenase
      Marmoset Flavin-Containing Monooxygenase 3 in the Liver Is a Major Benzydamine and Sulindac Sulfide Oxygenase
      Shotaro Uehara, Makiko Shimizu, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2017, 45 (5) 497-500; DOI: https://doi.org/10.1124/dmd.117.075184

  2. Ishii, Sakura

    1. Marmoset Cytochrome P450 3A4 Ortholog Expressed in Liver and Small-Intestine Tissues Efficiently Metabolizes Midazolam, Alprazolam, Nifedipine, and Testosterone
      Shotaro Uehara, Yasuhiro Uno, Kazuyuki Nakanishi, Sakura Ishii, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2017, 45 (5) 457-467; DOI: https://doi.org/10.1124/dmd.116.074898

J

  1. Jiang, Jingfang

    1. Nimesulide and 4′-Hydroxynimesulide as Bile Acid Transporters Inhibitors Are Contributory Factors for Drug-Induced Cholestasis
      Lei Zhou, Xiaoyan Pang, Jingfang Jiang, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition May 2017, 45 (5) 441-448; DOI: https://doi.org/10.1124/dmd.116.074104

  2. Jilek, Joseph L.

    1. Effects of MicroRNA-34a on the Pharmacokinetics of Cytochrome P450 Probe Drugs in Mice
      Joseph L. Jilek, Ye Tian and Ai-Ming Yu
      Drug Metabolism and Disposition May 2017, 45 (5) 512-522; DOI: https://doi.org/10.1124/dmd.116.074344

  3. Jones, Christopher R.

    1. Open Access
      Microsomal and Cytosolic Scaling Factors in Dog and Human Kidney Cortex and Application for In Vitro-In Vivo Extrapolation of Renal Metabolic Clearance
      Daniel Scotcher, Sarah Billington, Jay Brown, Christopher R. Jones, Colin D. A. Brown, Amin Rostami-Hodjegan and Aleksandra Galetin
      Drug Metabolism and Disposition May 2017, 45 (5) 556-568; DOI: https://doi.org/10.1124/dmd.117.075242

  4. Jusko, William J.

    1. Effect of Disease-Related Changes in Plasma Albumin on the Pharmacokinetics of Naproxen in Male and Female Arthritic Rats
      Xiaonan Li, Debra C. DuBois, Richard R. Almon and William J. Jusko
      Drug Metabolism and Disposition May 2017, 45 (5) 476-483; DOI: https://doi.org/10.1124/dmd.116.074500
    2. Modeling Sex Differences in Pharmacokinetics, Pharmacodynamics, and Disease Progression Effects of Naproxen in Rats with Collagen-Induced Arthritis
      Xiaonan Li, Debra C. DuBois, Richard R. Almon and William J. Jusko
      Drug Metabolism and Disposition May 2017, 45 (5) 484-491; DOI: https://doi.org/10.1124/dmd.116.074526

K

  1. Kalgutkar, Amit S.

    1. Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome
      Jennifer Q. Dong, James R. Gosset, Odette A. Fahmi, Zhiwu Lin, Jeffrey R. Chabot, Steven G. Terra, Vu Le, Kristin Chidsey, Parya Nouri, Albert Kim, Leonard Buckbinder and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2017, 45 (5) 501-511; DOI: https://doi.org/10.1124/dmd.116.074476

  2. Khojasteh, S. Cyrus

    1. Novel Mechanism of Decyanation of GDC-0425 by Cytochrome P450
      Ryan H. Takahashi, Jason S. Halladay, Michael Siu, Yuan Chen, Cornelis E. C. A. Hop, S. Cyrus Khojasteh and Shuguang Ma
      Drug Metabolism and Disposition May 2017, 45 (5) 430-440; DOI: https://doi.org/10.1124/dmd.116.074336

  3. Kim, Albert

    1. Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome
      Jennifer Q. Dong, James R. Gosset, Odette A. Fahmi, Zhiwu Lin, Jeffrey R. Chabot, Steven G. Terra, Vu Le, Kristin Chidsey, Parya Nouri, Albert Kim, Leonard Buckbinder and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2017, 45 (5) 501-511; DOI: https://doi.org/10.1124/dmd.116.074476

  4. Klein, Kai

    1. Midostaurin, a Novel Protein Kinase Inhibitor for the Treatment of Acute Myelogenous Leukemia: Insights from Human Absorption, Metabolism, and Excretion Studies of a BDDCS II Drug
      Handan He, Phi Tran, Helen Gu, Vivienne Tedesco, Jin Zhang, Wen Lin, Ewa Gatlik, Kai Klein and Tycho Heimbach
      Drug Metabolism and Disposition May 2017, 45 (5) 540-555; DOI: https://doi.org/10.1124/dmd.116.072744

  5. Kosa, Rachel E.

    1. Novel Method to Predict In Vivo Liver-to-Plasma Kpuu for OATP Substrates Using Suspension Hepatocytes
      Keith Riccardi, Jian Lin, Zhenhong Li, Mark Niosi, Sangwoo Ryu, Wenyi Hua, Karen Atkinson, Rachel E. Kosa, John Litchfield and Li Di
      Drug Metabolism and Disposition May 2017, 45 (5) 576-580; DOI: https://doi.org/10.1124/dmd.116.074575

L

  1. Lake, Brian G.

    1. Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages
      Gina Song, Xueying Sun, Ronald N. Hines, D. Gail McCarver, Brian G. Lake, Thomas G. Osimitz, Moire R. Creek, Harvey J. Clewell and Miyoung Yoon
      Drug Metabolism and Disposition May 2017, 45 (5) 468-475; DOI: https://doi.org/10.1124/dmd.116.074583

  2. Le, Vu

    1. Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome
      Jennifer Q. Dong, James R. Gosset, Odette A. Fahmi, Zhiwu Lin, Jeffrey R. Chabot, Steven G. Terra, Vu Le, Kristin Chidsey, Parya Nouri, Albert Kim, Leonard Buckbinder and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2017, 45 (5) 501-511; DOI: https://doi.org/10.1124/dmd.116.074476

  3. Li, Xiaonan

    1. Effect of Disease-Related Changes in Plasma Albumin on the Pharmacokinetics of Naproxen in Male and Female Arthritic Rats
      Xiaonan Li, Debra C. DuBois, Richard R. Almon and William J. Jusko
      Drug Metabolism and Disposition May 2017, 45 (5) 476-483; DOI: https://doi.org/10.1124/dmd.116.074500
    2. Modeling Sex Differences in Pharmacokinetics, Pharmacodynamics, and Disease Progression Effects of Naproxen in Rats with Collagen-Induced Arthritis
      Xiaonan Li, Debra C. DuBois, Richard R. Almon and William J. Jusko
      Drug Metabolism and Disposition May 2017, 45 (5) 484-491; DOI: https://doi.org/10.1124/dmd.116.074526

  4. Li, Yi

    1. Correlation between Membrane Protein Expression Levels and Transcellular Transport Activity for Breast Cancer Resistance Protein
      Houfu Liu, Liang Huang, Yi Li, Tingting Fu, Xueying Sun, Yan-Yan Zhang, Ruina Gao, Qingfang Chen, Wandong Zhang, Jasminder Sahi, Scott Summerfield and Kelly Dong
      Drug Metabolism and Disposition May 2017, 45 (5) 449-456; DOI: https://doi.org/10.1124/dmd.116.074245

  5. Li, Zhenhong

    1. Novel Method to Predict In Vivo Liver-to-Plasma Kpuu for OATP Substrates Using Suspension Hepatocytes
      Keith Riccardi, Jian Lin, Zhenhong Li, Mark Niosi, Sangwoo Ryu, Wenyi Hua, Karen Atkinson, Rachel E. Kosa, John Litchfield and Li Di
      Drug Metabolism and Disposition May 2017, 45 (5) 576-580; DOI: https://doi.org/10.1124/dmd.116.074575

  6. Lin, Jian

    1. Novel Method to Predict In Vivo Liver-to-Plasma Kpuu for OATP Substrates Using Suspension Hepatocytes
      Keith Riccardi, Jian Lin, Zhenhong Li, Mark Niosi, Sangwoo Ryu, Wenyi Hua, Karen Atkinson, Rachel E. Kosa, John Litchfield and Li Di
      Drug Metabolism and Disposition May 2017, 45 (5) 576-580; DOI: https://doi.org/10.1124/dmd.116.074575

  7. Lin, Wen

    1. Midostaurin, a Novel Protein Kinase Inhibitor for the Treatment of Acute Myelogenous Leukemia: Insights from Human Absorption, Metabolism, and Excretion Studies of a BDDCS II Drug
      Handan He, Phi Tran, Helen Gu, Vivienne Tedesco, Jin Zhang, Wen Lin, Ewa Gatlik, Kai Klein and Tycho Heimbach
      Drug Metabolism and Disposition May 2017, 45 (5) 540-555; DOI: https://doi.org/10.1124/dmd.116.072744

  8. Lin, Zhiwu

    1. Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome
      Jennifer Q. Dong, James R. Gosset, Odette A. Fahmi, Zhiwu Lin, Jeffrey R. Chabot, Steven G. Terra, Vu Le, Kristin Chidsey, Parya Nouri, Albert Kim, Leonard Buckbinder and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2017, 45 (5) 501-511; DOI: https://doi.org/10.1124/dmd.116.074476

  9. Litchfield, John

    1. Novel Method to Predict In Vivo Liver-to-Plasma Kpuu for OATP Substrates Using Suspension Hepatocytes
      Keith Riccardi, Jian Lin, Zhenhong Li, Mark Niosi, Sangwoo Ryu, Wenyi Hua, Karen Atkinson, Rachel E. Kosa, John Litchfield and Li Di
      Drug Metabolism and Disposition May 2017, 45 (5) 576-580; DOI: https://doi.org/10.1124/dmd.116.074575

  10. Liu, Houfu

    1. Correlation between Membrane Protein Expression Levels and Transcellular Transport Activity for Breast Cancer Resistance Protein
      Houfu Liu, Liang Huang, Yi Li, Tingting Fu, Xueying Sun, Yan-Yan Zhang, Ruina Gao, Qingfang Chen, Wandong Zhang, Jasminder Sahi, Scott Summerfield and Kelly Dong
      Drug Metabolism and Disposition May 2017, 45 (5) 449-456; DOI: https://doi.org/10.1124/dmd.116.074245

M

  1. Ma, Shuguang

    1. Novel Mechanism of Decyanation of GDC-0425 by Cytochrome P450
      Ryan H. Takahashi, Jason S. Halladay, Michael Siu, Yuan Chen, Cornelis E. C. A. Hop, S. Cyrus Khojasteh and Shuguang Ma
      Drug Metabolism and Disposition May 2017, 45 (5) 430-440; DOI: https://doi.org/10.1124/dmd.116.074336

  2. McCarver, D. Gail

    1. Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages
      Gina Song, Xueying Sun, Ronald N. Hines, D. Gail McCarver, Brian G. Lake, Thomas G. Osimitz, Moire R. Creek, Harvey J. Clewell and Miyoung Yoon
      Drug Metabolism and Disposition May 2017, 45 (5) 468-475; DOI: https://doi.org/10.1124/dmd.116.074583

  3. Milne, Robert W.

    1. Effect of Garlic, Gingko, and St. John’s Wort Extracts on the Pharmacokinetics of Fexofenadine: A Mechanistic Study
      Jasmina Turkanovic, Michael B. Ward, Jacobus P. Gerber and Robert W. Milne
      Drug Metabolism and Disposition May 2017, 45 (5) 569-575; DOI: https://doi.org/10.1124/dmd.116.073528

N

  1. Nakanishi, Kazuyuki

    1. Marmoset Cytochrome P450 3A4 Ortholog Expressed in Liver and Small-Intestine Tissues Efficiently Metabolizes Midazolam, Alprazolam, Nifedipine, and Testosterone
      Shotaro Uehara, Yasuhiro Uno, Kazuyuki Nakanishi, Sakura Ishii, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2017, 45 (5) 457-467; DOI: https://doi.org/10.1124/dmd.116.074898

  2. Negishi, Masahiko

    1. Phenobarbital Meets Phosphorylation of Nuclear Receptors
      Masahiko Negishi
      Drug Metabolism and Disposition May 2017, 45 (5) 532-539; DOI: https://doi.org/10.1124/dmd.116.074872

  3. Niosi, Mark

    1. Novel Method to Predict In Vivo Liver-to-Plasma Kpuu for OATP Substrates Using Suspension Hepatocytes
      Keith Riccardi, Jian Lin, Zhenhong Li, Mark Niosi, Sangwoo Ryu, Wenyi Hua, Karen Atkinson, Rachel E. Kosa, John Litchfield and Li Di
      Drug Metabolism and Disposition May 2017, 45 (5) 576-580; DOI: https://doi.org/10.1124/dmd.116.074575

  4. Nouri, Parya

    1. Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome
      Jennifer Q. Dong, James R. Gosset, Odette A. Fahmi, Zhiwu Lin, Jeffrey R. Chabot, Steven G. Terra, Vu Le, Kristin Chidsey, Parya Nouri, Albert Kim, Leonard Buckbinder and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2017, 45 (5) 501-511; DOI: https://doi.org/10.1124/dmd.116.074476

O

  1. Osimitz, Thomas G.

    1. Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages
      Gina Song, Xueying Sun, Ronald N. Hines, D. Gail McCarver, Brian G. Lake, Thomas G. Osimitz, Moire R. Creek, Harvey J. Clewell and Miyoung Yoon
      Drug Metabolism and Disposition May 2017, 45 (5) 468-475; DOI: https://doi.org/10.1124/dmd.116.074583

P

  1. Pang, Xiaoyan

    1. Nimesulide and 4′-Hydroxynimesulide as Bile Acid Transporters Inhibitors Are Contributory Factors for Drug-Induced Cholestasis
      Lei Zhou, Xiaoyan Pang, Jingfang Jiang, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition May 2017, 45 (5) 441-448; DOI: https://doi.org/10.1124/dmd.116.074104

  2. Poller, Birk

    1. Assessing the Risk of Drug-Induced Cholestasis Using Unbound Intrahepatic Concentrations
      Julia Riede, Birk Poller, Jörg Huwyler and Gian Camenisch
      Drug Metabolism and Disposition May 2017, 45 (5) 523-531; DOI: https://doi.org/10.1124/dmd.116.074179

R

  1. Riccardi, Keith

    1. Novel Method to Predict In Vivo Liver-to-Plasma Kpuu for OATP Substrates Using Suspension Hepatocytes
      Keith Riccardi, Jian Lin, Zhenhong Li, Mark Niosi, Sangwoo Ryu, Wenyi Hua, Karen Atkinson, Rachel E. Kosa, John Litchfield and Li Di
      Drug Metabolism and Disposition May 2017, 45 (5) 576-580; DOI: https://doi.org/10.1124/dmd.116.074575

  2. Riede, Julia

    1. Assessing the Risk of Drug-Induced Cholestasis Using Unbound Intrahepatic Concentrations
      Julia Riede, Birk Poller, Jörg Huwyler and Gian Camenisch
      Drug Metabolism and Disposition May 2017, 45 (5) 523-531; DOI: https://doi.org/10.1124/dmd.116.074179

  3. Rostami-Hodjegan, Amin

    1. Open Access
      Microsomal and Cytosolic Scaling Factors in Dog and Human Kidney Cortex and Application for In Vitro-In Vivo Extrapolation of Renal Metabolic Clearance
      Daniel Scotcher, Sarah Billington, Jay Brown, Christopher R. Jones, Colin D. A. Brown, Amin Rostami-Hodjegan and Aleksandra Galetin
      Drug Metabolism and Disposition May 2017, 45 (5) 556-568; DOI: https://doi.org/10.1124/dmd.117.075242

  4. Ryu, Sangwoo

    1. Novel Method to Predict In Vivo Liver-to-Plasma Kpuu for OATP Substrates Using Suspension Hepatocytes
      Keith Riccardi, Jian Lin, Zhenhong Li, Mark Niosi, Sangwoo Ryu, Wenyi Hua, Karen Atkinson, Rachel E. Kosa, John Litchfield and Li Di
      Drug Metabolism and Disposition May 2017, 45 (5) 576-580; DOI: https://doi.org/10.1124/dmd.116.074575

S

  1. Sahi, Jasminder

    1. Correlation between Membrane Protein Expression Levels and Transcellular Transport Activity for Breast Cancer Resistance Protein
      Houfu Liu, Liang Huang, Yi Li, Tingting Fu, Xueying Sun, Yan-Yan Zhang, Ruina Gao, Qingfang Chen, Wandong Zhang, Jasminder Sahi, Scott Summerfield and Kelly Dong
      Drug Metabolism and Disposition May 2017, 45 (5) 449-456; DOI: https://doi.org/10.1124/dmd.116.074245

  2. Sasaki, Erika

    1. Marmoset Cytochrome P450 3A4 Ortholog Expressed in Liver and Small-Intestine Tissues Efficiently Metabolizes Midazolam, Alprazolam, Nifedipine, and Testosterone
      Shotaro Uehara, Yasuhiro Uno, Kazuyuki Nakanishi, Sakura Ishii, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2017, 45 (5) 457-467; DOI: https://doi.org/10.1124/dmd.116.074898
    2. Marmoset Flavin-Containing Monooxygenase 3 in the Liver Is a Major Benzydamine and Sulindac Sulfide Oxygenase
      Marmoset Flavin-Containing Monooxygenase 3 in the Liver Is a Major Benzydamine and Sulindac Sulfide Oxygenase
      Shotaro Uehara, Makiko Shimizu, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2017, 45 (5) 497-500; DOI: https://doi.org/10.1124/dmd.117.075184

  3. Scotcher, Daniel

    1. Open Access
      Microsomal and Cytosolic Scaling Factors in Dog and Human Kidney Cortex and Application for In Vitro-In Vivo Extrapolation of Renal Metabolic Clearance
      Daniel Scotcher, Sarah Billington, Jay Brown, Christopher R. Jones, Colin D. A. Brown, Amin Rostami-Hodjegan and Aleksandra Galetin
      Drug Metabolism and Disposition May 2017, 45 (5) 556-568; DOI: https://doi.org/10.1124/dmd.117.075242

  4. Shimizu, Makiko

    1. Marmoset Flavin-Containing Monooxygenase 3 in the Liver Is a Major Benzydamine and Sulindac Sulfide Oxygenase
      Marmoset Flavin-Containing Monooxygenase 3 in the Liver Is a Major Benzydamine and Sulindac Sulfide Oxygenase
      Shotaro Uehara, Makiko Shimizu, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2017, 45 (5) 497-500; DOI: https://doi.org/10.1124/dmd.117.075184

  5. Siu, Michael

    1. Novel Mechanism of Decyanation of GDC-0425 by Cytochrome P450
      Ryan H. Takahashi, Jason S. Halladay, Michael Siu, Yuan Chen, Cornelis E. C. A. Hop, S. Cyrus Khojasteh and Shuguang Ma
      Drug Metabolism and Disposition May 2017, 45 (5) 430-440; DOI: https://doi.org/10.1124/dmd.116.074336

  6. Song, Gina

    1. Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages
      Gina Song, Xueying Sun, Ronald N. Hines, D. Gail McCarver, Brian G. Lake, Thomas G. Osimitz, Moire R. Creek, Harvey J. Clewell and Miyoung Yoon
      Drug Metabolism and Disposition May 2017, 45 (5) 468-475; DOI: https://doi.org/10.1124/dmd.116.074583

  7. Summerfield, Scott

    1. Correlation between Membrane Protein Expression Levels and Transcellular Transport Activity for Breast Cancer Resistance Protein
      Houfu Liu, Liang Huang, Yi Li, Tingting Fu, Xueying Sun, Yan-Yan Zhang, Ruina Gao, Qingfang Chen, Wandong Zhang, Jasminder Sahi, Scott Summerfield and Kelly Dong
      Drug Metabolism and Disposition May 2017, 45 (5) 449-456; DOI: https://doi.org/10.1124/dmd.116.074245

  8. Sun, Xueying

    1. Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages
      Gina Song, Xueying Sun, Ronald N. Hines, D. Gail McCarver, Brian G. Lake, Thomas G. Osimitz, Moire R. Creek, Harvey J. Clewell and Miyoung Yoon
      Drug Metabolism and Disposition May 2017, 45 (5) 468-475; DOI: https://doi.org/10.1124/dmd.116.074583
    2. Correlation between Membrane Protein Expression Levels and Transcellular Transport Activity for Breast Cancer Resistance Protein
      Houfu Liu, Liang Huang, Yi Li, Tingting Fu, Xueying Sun, Yan-Yan Zhang, Ruina Gao, Qingfang Chen, Wandong Zhang, Jasminder Sahi, Scott Summerfield and Kelly Dong
      Drug Metabolism and Disposition May 2017, 45 (5) 449-456; DOI: https://doi.org/10.1124/dmd.116.074245

T

  1. Takahashi, Ryan H.

    1. Novel Mechanism of Decyanation of GDC-0425 by Cytochrome P450
      Ryan H. Takahashi, Jason S. Halladay, Michael Siu, Yuan Chen, Cornelis E. C. A. Hop, S. Cyrus Khojasteh and Shuguang Ma
      Drug Metabolism and Disposition May 2017, 45 (5) 430-440; DOI: https://doi.org/10.1124/dmd.116.074336

  2. Tedesco, Vivienne

    1. Midostaurin, a Novel Protein Kinase Inhibitor for the Treatment of Acute Myelogenous Leukemia: Insights from Human Absorption, Metabolism, and Excretion Studies of a BDDCS II Drug
      Handan He, Phi Tran, Helen Gu, Vivienne Tedesco, Jin Zhang, Wen Lin, Ewa Gatlik, Kai Klein and Tycho Heimbach
      Drug Metabolism and Disposition May 2017, 45 (5) 540-555; DOI: https://doi.org/10.1124/dmd.116.072744

  3. Terra, Steven G.

    1. Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome
      Jennifer Q. Dong, James R. Gosset, Odette A. Fahmi, Zhiwu Lin, Jeffrey R. Chabot, Steven G. Terra, Vu Le, Kristin Chidsey, Parya Nouri, Albert Kim, Leonard Buckbinder and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2017, 45 (5) 501-511; DOI: https://doi.org/10.1124/dmd.116.074476

  4. Tian, Ye

    1. Effects of MicroRNA-34a on the Pharmacokinetics of Cytochrome P450 Probe Drugs in Mice
      Joseph L. Jilek, Ye Tian and Ai-Ming Yu
      Drug Metabolism and Disposition May 2017, 45 (5) 512-522; DOI: https://doi.org/10.1124/dmd.116.074344

  5. Tran, Phi

    1. Midostaurin, a Novel Protein Kinase Inhibitor for the Treatment of Acute Myelogenous Leukemia: Insights from Human Absorption, Metabolism, and Excretion Studies of a BDDCS II Drug
      Handan He, Phi Tran, Helen Gu, Vivienne Tedesco, Jin Zhang, Wen Lin, Ewa Gatlik, Kai Klein and Tycho Heimbach
      Drug Metabolism and Disposition May 2017, 45 (5) 540-555; DOI: https://doi.org/10.1124/dmd.116.072744

  6. Turkanovic, Jasmina

    1. Effect of Garlic, Gingko, and St. John’s Wort Extracts on the Pharmacokinetics of Fexofenadine: A Mechanistic Study
      Jasmina Turkanovic, Michael B. Ward, Jacobus P. Gerber and Robert W. Milne
      Drug Metabolism and Disposition May 2017, 45 (5) 569-575; DOI: https://doi.org/10.1124/dmd.116.073528

U

  1. Uehara, Shotaro

    1. Marmoset Cytochrome P450 3A4 Ortholog Expressed in Liver and Small-Intestine Tissues Efficiently Metabolizes Midazolam, Alprazolam, Nifedipine, and Testosterone
      Shotaro Uehara, Yasuhiro Uno, Kazuyuki Nakanishi, Sakura Ishii, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2017, 45 (5) 457-467; DOI: https://doi.org/10.1124/dmd.116.074898
    2. Marmoset Flavin-Containing Monooxygenase 3 in the Liver Is a Major Benzydamine and Sulindac Sulfide Oxygenase
      Marmoset Flavin-Containing Monooxygenase 3 in the Liver Is a Major Benzydamine and Sulindac Sulfide Oxygenase
      Shotaro Uehara, Makiko Shimizu, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2017, 45 (5) 497-500; DOI: https://doi.org/10.1124/dmd.117.075184

  2. Uno, Yasuhiro

    1. Marmoset Cytochrome P450 3A4 Ortholog Expressed in Liver and Small-Intestine Tissues Efficiently Metabolizes Midazolam, Alprazolam, Nifedipine, and Testosterone
      Shotaro Uehara, Yasuhiro Uno, Kazuyuki Nakanishi, Sakura Ishii, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2017, 45 (5) 457-467; DOI: https://doi.org/10.1124/dmd.116.074898
    2. Marmoset Flavin-Containing Monooxygenase 3 in the Liver Is a Major Benzydamine and Sulindac Sulfide Oxygenase
      Marmoset Flavin-Containing Monooxygenase 3 in the Liver Is a Major Benzydamine and Sulindac Sulfide Oxygenase
      Shotaro Uehara, Makiko Shimizu, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2017, 45 (5) 497-500; DOI: https://doi.org/10.1124/dmd.117.075184

W

  1. Ward, Michael B.

    1. Effect of Garlic, Gingko, and St. John’s Wort Extracts on the Pharmacokinetics of Fexofenadine: A Mechanistic Study
      Jasmina Turkanovic, Michael B. Ward, Jacobus P. Gerber and Robert W. Milne
      Drug Metabolism and Disposition May 2017, 45 (5) 569-575; DOI: https://doi.org/10.1124/dmd.116.073528

  2. Waters, Nigel J.

    1. Implications for Metabolite Quantification by Mass Spectrometry in the Absence of Authentic Standards
      Panos Hatsis, Nigel J. Waters and Upendra A. Argikar
      Drug Metabolism and Disposition May 2017, 45 (5) 492-496; DOI: https://doi.org/10.1124/dmd.117.075259

Y

  1. Yamazaki, Hiroshi

    1. Marmoset Cytochrome P450 3A4 Ortholog Expressed in Liver and Small-Intestine Tissues Efficiently Metabolizes Midazolam, Alprazolam, Nifedipine, and Testosterone
      Shotaro Uehara, Yasuhiro Uno, Kazuyuki Nakanishi, Sakura Ishii, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2017, 45 (5) 457-467; DOI: https://doi.org/10.1124/dmd.116.074898
    2. Marmoset Flavin-Containing Monooxygenase 3 in the Liver Is a Major Benzydamine and Sulindac Sulfide Oxygenase
      Marmoset Flavin-Containing Monooxygenase 3 in the Liver Is a Major Benzydamine and Sulindac Sulfide Oxygenase
      Shotaro Uehara, Makiko Shimizu, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2017, 45 (5) 497-500; DOI: https://doi.org/10.1124/dmd.117.075184

  2. Yoon, Miyoung

    1. Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages
      Gina Song, Xueying Sun, Ronald N. Hines, D. Gail McCarver, Brian G. Lake, Thomas G. Osimitz, Moire R. Creek, Harvey J. Clewell and Miyoung Yoon
      Drug Metabolism and Disposition May 2017, 45 (5) 468-475; DOI: https://doi.org/10.1124/dmd.116.074583

  3. Yu, Ai-Ming

    1. Effects of MicroRNA-34a on the Pharmacokinetics of Cytochrome P450 Probe Drugs in Mice
      Joseph L. Jilek, Ye Tian and Ai-Ming Yu
      Drug Metabolism and Disposition May 2017, 45 (5) 512-522; DOI: https://doi.org/10.1124/dmd.116.074344

Z

  1. Zhang, Jin

    1. Midostaurin, a Novel Protein Kinase Inhibitor for the Treatment of Acute Myelogenous Leukemia: Insights from Human Absorption, Metabolism, and Excretion Studies of a BDDCS II Drug
      Handan He, Phi Tran, Helen Gu, Vivienne Tedesco, Jin Zhang, Wen Lin, Ewa Gatlik, Kai Klein and Tycho Heimbach
      Drug Metabolism and Disposition May 2017, 45 (5) 540-555; DOI: https://doi.org/10.1124/dmd.116.072744

  2. Zhang, Wandong

    1. Correlation between Membrane Protein Expression Levels and Transcellular Transport Activity for Breast Cancer Resistance Protein
      Houfu Liu, Liang Huang, Yi Li, Tingting Fu, Xueying Sun, Yan-Yan Zhang, Ruina Gao, Qingfang Chen, Wandong Zhang, Jasminder Sahi, Scott Summerfield and Kelly Dong
      Drug Metabolism and Disposition May 2017, 45 (5) 449-456; DOI: https://doi.org/10.1124/dmd.116.074245

  3. Zhang, Yan-Yan

    1. Correlation between Membrane Protein Expression Levels and Transcellular Transport Activity for Breast Cancer Resistance Protein
      Houfu Liu, Liang Huang, Yi Li, Tingting Fu, Xueying Sun, Yan-Yan Zhang, Ruina Gao, Qingfang Chen, Wandong Zhang, Jasminder Sahi, Scott Summerfield and Kelly Dong
      Drug Metabolism and Disposition May 2017, 45 (5) 449-456; DOI: https://doi.org/10.1124/dmd.116.074245

  4. Zhong, Dafang

    1. Nimesulide and 4′-Hydroxynimesulide as Bile Acid Transporters Inhibitors Are Contributory Factors for Drug-Induced Cholestasis
      Lei Zhou, Xiaoyan Pang, Jingfang Jiang, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition May 2017, 45 (5) 441-448; DOI: https://doi.org/10.1124/dmd.116.074104

  5. Zhou, Lei

    1. Nimesulide and 4′-Hydroxynimesulide as Bile Acid Transporters Inhibitors Are Contributory Factors for Drug-Induced Cholestasis
      Lei Zhou, Xiaoyan Pang, Jingfang Jiang, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition May 2017, 45 (5) 441-448; DOI: https://doi.org/10.1124/dmd.116.074104
Back to top

In this issue

Advertisement