Research ArticleArticle
Novel Mechanism of Decyanation of GDC-0425 by Cytochrome P450
Ryan H. Takahashi, Jason S. Halladay, Michael Siu, Yuan Chen, Cornelis E. C. A. Hop, S. Cyrus Khojasteh and Shuguang Ma
Drug Metabolism and Disposition May 2017, 45 (5) 430-440; DOI: https://doi.org/10.1124/dmd.116.074336
Ryan H. Takahashi
Departments of Drug Metabolism and Pharmacokinetics (R.H.T., J.S.H., Y.C., C.E.C.A.H., S.C.K., S.M.), and Discovery Chemistry (M.S.), Genentech, Inc., 1 DNA Way, South San Francisco, California
Jason S. Halladay
Departments of Drug Metabolism and Pharmacokinetics (R.H.T., J.S.H., Y.C., C.E.C.A.H., S.C.K., S.M.), and Discovery Chemistry (M.S.), Genentech, Inc., 1 DNA Way, South San Francisco, California
Michael Siu
Departments of Drug Metabolism and Pharmacokinetics (R.H.T., J.S.H., Y.C., C.E.C.A.H., S.C.K., S.M.), and Discovery Chemistry (M.S.), Genentech, Inc., 1 DNA Way, South San Francisco, California
Yuan Chen
Departments of Drug Metabolism and Pharmacokinetics (R.H.T., J.S.H., Y.C., C.E.C.A.H., S.C.K., S.M.), and Discovery Chemistry (M.S.), Genentech, Inc., 1 DNA Way, South San Francisco, California
Cornelis E. C. A. Hop
Departments of Drug Metabolism and Pharmacokinetics (R.H.T., J.S.H., Y.C., C.E.C.A.H., S.C.K., S.M.), and Discovery Chemistry (M.S.), Genentech, Inc., 1 DNA Way, South San Francisco, California
S. Cyrus Khojasteh
Departments of Drug Metabolism and Pharmacokinetics (R.H.T., J.S.H., Y.C., C.E.C.A.H., S.C.K., S.M.), and Discovery Chemistry (M.S.), Genentech, Inc., 1 DNA Way, South San Francisco, California
Shuguang Ma
Departments of Drug Metabolism and Pharmacokinetics (R.H.T., J.S.H., Y.C., C.E.C.A.H., S.C.K., S.M.), and Discovery Chemistry (M.S.), Genentech, Inc., 1 DNA Way, South San Francisco, California

Submit a Response to This Article
Jump to comment:
No eLetters have been published for this article.
In this issue
Research ArticleArticle
Trace Circulating Thiocyanate Is Derived from GDC-0425
Ryan H. Takahashi, Jason S. Halladay, Michael Siu, Yuan Chen, Cornelis E. C. A. Hop, S. Cyrus Khojasteh and Shuguang Ma
Drug Metabolism and Disposition May 1, 2017, 45 (5) 430-440; DOI: https://doi.org/10.1124/dmd.116.074336
Research ArticleArticle
Trace Circulating Thiocyanate Is Derived from GDC-0425
Ryan H. Takahashi, Jason S. Halladay, Michael Siu, Yuan Chen, Cornelis E. C. A. Hop, S. Cyrus Khojasteh and Shuguang Ma
Drug Metabolism and Disposition May 1, 2017, 45 (5) 430-440; DOI: https://doi.org/10.1124/dmd.116.074336
Jump to section
Related Articles
Cited By...
More in this TOC Section
Similar Articles
Advertisement