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Research ArticleArticle

Effects of MicroRNA-34a on the Pharmacokinetics of Cytochrome P450 Probe Drugs in Mice

Joseph L. Jilek, Ye Tian and Ai-Ming Yu
Drug Metabolism and Disposition May 2017, 45 (5) 512-522; DOI: https://doi.org/10.1124/dmd.116.074344
Joseph L. Jilek
Department of Biochemistry and Molecular Medicine, Comprehensive Cancer Center, University of California Davis School of Medicine, Sacramento, California (J.L.J., Y.T., A.-M.Y.); and Key Laboratory for Space Bioscience and Biotechnology, Institute of Special Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi, China (Y.T.)
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Ye Tian
Department of Biochemistry and Molecular Medicine, Comprehensive Cancer Center, University of California Davis School of Medicine, Sacramento, California (J.L.J., Y.T., A.-M.Y.); and Key Laboratory for Space Bioscience and Biotechnology, Institute of Special Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi, China (Y.T.)
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Ai-Ming Yu
Department of Biochemistry and Molecular Medicine, Comprehensive Cancer Center, University of California Davis School of Medicine, Sacramento, California (J.L.J., Y.T., A.-M.Y.); and Key Laboratory for Space Bioscience and Biotechnology, Institute of Special Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi, China (Y.T.)
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Article Information

vol. 45 no. 5 512-522
DOI 
https://doi.org/10.1124/dmd.116.074344
PubMed 
28254952

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received November 20, 2016
  • Accepted March 1, 2017
  • Published online April 14, 2017.

Article Versions

  • Earlier version (March 2, 2017 - 07:42).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2017 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Joseph L. Jilek,
  2. Ye Tian, and
  3. Ai-Ming Yu
  1. Department of Biochemistry and Molecular Medicine, Comprehensive Cancer Center, University of California Davis School of Medicine, Sacramento, California (J.L.J., Y.T., A.-M.Y.); and Key Laboratory for Space Bioscience and Biotechnology, Institute of Special Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi, China (Y.T.)
  1. Address correspondence to:
    Ai-Ming Yu, Department of Biochemistry and Molecular Medicine, University of California Davis School of Medicine, 2700 Stockton Boulevard, Room 2132, Sacramento, CA 95817. E-mail: aimyu{at}ucdavis.edu
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Drug Metabolism and Disposition: 45 (5)
Drug Metabolism and Disposition
Vol. 45, Issue 5
1 May 2017
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Research ArticleArticle

miR-34a Marginally Alters P450 Probe Drug PK

Joseph L. Jilek, Ye Tian and Ai-Ming Yu
Drug Metabolism and Disposition May 1, 2017, 45 (5) 512-522; DOI: https://doi.org/10.1124/dmd.116.074344

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Research ArticleArticle

miR-34a Marginally Alters P450 Probe Drug PK

Joseph L. Jilek, Ye Tian and Ai-Ming Yu
Drug Metabolism and Disposition May 1, 2017, 45 (5) 512-522; DOI: https://doi.org/10.1124/dmd.116.074344
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