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Drug Metabolism & Disposition

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  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
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Index by author

June 01, 2017; Volume 45,Issue 6
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Achour, Brahim

    1. You have access
      Global Proteomic Analysis of Human Liver Microsomes: Rapid Characterization and Quantification of Hepatic Drug-Metabolizing Enzymes
      Brahim Achour, Hajar Al Feteisi, Francesco Lanucara, Amin Rostami-Hodjegan and Jill Barber
      Drug Metabolism and Disposition June 2017, 45 (6) 666-675; DOI: https://doi.org/10.1124/dmd.116.074732
  2. Ahire, Deepak

    1. You have access
      Metabolite Identification, Reaction Phenotyping, and Retrospective Drug-Drug Interaction Predictions of 17-Deacetylnorgestimate, the Active Component of the Oral Contraceptive Norgestimate
      Deepak Ahire, Sarmistha Sinha, Barry Brock, Ramaswamy Iyer, Sandhya Mandlekar and Murali Subramanian
      Drug Metabolism and Disposition June 2017, 45 (6) 676-685; DOI: https://doi.org/10.1124/dmd.116.073940
  3. Al Feteisi, Hajar

    1. You have access
      Global Proteomic Analysis of Human Liver Microsomes: Rapid Characterization and Quantification of Hepatic Drug-Metabolizing Enzymes
      Brahim Achour, Hajar Al Feteisi, Francesco Lanucara, Amin Rostami-Hodjegan and Jill Barber
      Drug Metabolism and Disposition June 2017, 45 (6) 666-675; DOI: https://doi.org/10.1124/dmd.116.074732
  4. Amaral, Kirsten

    1. You have access
      Human Enterocytes as an In Vitro Model for the Evaluation of Intestinal Drug Metabolism: Characterization of Drug-Metabolizing Enzyme Activities of Cryopreserved Human Enterocytes from Twenty-Four Donors
      Ming-Chih David Ho, Nicholas Ring, Kirsten Amaral, Utkarsh Doshi and Albert P. Li
      Drug Metabolism and Disposition June 2017, 45 (6) 686-691; DOI: https://doi.org/10.1124/dmd.116.074377
  5. Aubé, Jeffrey

    1. Structural and Functional Evaluation of Clinically Relevant Inhibitors of Steroidogenic Cytochrome P450 17A1
      You have access
      Structural and Functional Evaluation of Clinically Relevant Inhibitors of Steroidogenic Cytochrome P450 17A1
      Elyse M. Petrunak, Steven A. Rogers, Jeffrey Aubé and Emily E. Scott
      Drug Metabolism and Disposition June 2017, 45 (6) 635-645; DOI: https://doi.org/10.1124/dmd.117.075317

B

  1. Bagul, Pravin

    1. You have access
      Coproporphyrin-I: A Fluorescent, Endogenous Optimal Probe Substrate for ABCC2 (MRP2) Suitable for Vesicle-Based MRP2 Inhibition Assay
      Ravindranath Reddy Gilibili, Sagnik Chatterjee, Pravin Bagul, Kathleen W. Mosure, Bokka Venkata Murali, T. Thanga Mariappan, Sandhya Mandlekar and Yurong Lai
      Drug Metabolism and Disposition June 2017, 45 (6) 604-611; DOI: https://doi.org/10.1124/dmd.116.074740
  2. Barber, Jill

    1. You have access
      Global Proteomic Analysis of Human Liver Microsomes: Rapid Characterization and Quantification of Hepatic Drug-Metabolizing Enzymes
      Brahim Achour, Hajar Al Feteisi, Francesco Lanucara, Amin Rostami-Hodjegan and Jill Barber
      Drug Metabolism and Disposition June 2017, 45 (6) 666-675; DOI: https://doi.org/10.1124/dmd.116.074732
  3. Boer, Jason

    1. You have access
      In Vitro Interactions of Epacadostat and its Major Metabolites with Human Efflux and Uptake Transporters: Implications for Pharmacokinetics and Drug Interactions
      Qiang Zhang, Yan Zhang, Jason Boer, Jack G. Shi, Peidi Hu, Sharon Diamond and Swamy Yeleswaram
      Drug Metabolism and Disposition June 2017, 45 (6) 612-623; DOI: https://doi.org/10.1124/dmd.116.074609
  4. Brock, Barry

    1. You have access
      Metabolite Identification, Reaction Phenotyping, and Retrospective Drug-Drug Interaction Predictions of 17-Deacetylnorgestimate, the Active Component of the Oral Contraceptive Norgestimate
      Deepak Ahire, Sarmistha Sinha, Barry Brock, Ramaswamy Iyer, Sandhya Mandlekar and Murali Subramanian
      Drug Metabolism and Disposition June 2017, 45 (6) 676-685; DOI: https://doi.org/10.1124/dmd.116.073940

C

  1. Chang, Jae H.

    1. You have access
      Applying Stable Isotope Labeled Amino Acids in Micropatterned Hepatocyte Coculture to Directly Determine the Degradation Rate Constant for CYP3A4
      Ryan H. Takahashi, Sheerin K. Shahidi-Latham, Susan Wong and Jae H. Chang
      Drug Metabolism and Disposition June 2017, 45 (6) 581-585; DOI: https://doi.org/10.1124/dmd.116.074393
  2. Chatterjee, Sagnik

    1. You have access
      Coproporphyrin-I: A Fluorescent, Endogenous Optimal Probe Substrate for ABCC2 (MRP2) Suitable for Vesicle-Based MRP2 Inhibition Assay
      Ravindranath Reddy Gilibili, Sagnik Chatterjee, Pravin Bagul, Kathleen W. Mosure, Bokka Venkata Murali, T. Thanga Mariappan, Sandhya Mandlekar and Yurong Lai
      Drug Metabolism and Disposition June 2017, 45 (6) 604-611; DOI: https://doi.org/10.1124/dmd.116.074740
  3. Chen, Jiamei

    1. High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      You have access
      High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      Jiamei Chen, Lijun Zhu, Xiaoyan Li, Haihui Zheng, Tongmeng Yan, Cong Xie, Sijing Zeng, Jia Yu, Huangyu Jiang, Linlin Lu, Xiaoxiao Qi, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition June 2017, 45 (6) 624-634; DOI: https://doi.org/10.1124/dmd.116.074682
  4. Chen, Liangfu

    1. You have access
      Prediction of the Transporter-Mediated Drug-Drug Interaction Potential of Dabrafenib and Its Major Circulating Metabolites
      Harma Ellens, Marta Johnson, Sarah K. Lawrence, Cory Watson, Liangfu Chen and Lauren E. Richards-Peterson
      Drug Metabolism and Disposition June 2017, 45 (6) 646-656; DOI: https://doi.org/10.1124/dmd.116.073932
  5. Chen, Xiaoyan

    1. You have access
      Increased Plasma Exposures of Conjugated Metabolites of Morinidazole in Renal Failure Patients: A Critical Role of Uremic Toxins
      Fandi Kong, Xiaoyan Pang, Kan Zhong, Zitao Guo, Xiuli Li, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition June 2017, 45 (6) 593-603; DOI: https://doi.org/10.1124/dmd.116.074492
  6. Cho, Takamasa

    1. You have access
      Prolactin Upregulates Female-Predominant P450 Gene Expressions and Downregulates Male-Predominant Gene Expressions in Mouse Liver
      Yuya Sato, Yoshikatsu Kaneko, Takamasa Cho, Kei Goto, Tadashi Otsuka, Suguru Yamamoto, Shin Goto, Hiroki Maruyama and Ichiei Narita
      Drug Metabolism and Disposition June 2017, 45 (6) 586-592; DOI: https://doi.org/10.1124/dmd.116.074658
  7. Chothe, Paresh P.

    1. You have access
      Quantitative Prediction of CYP3A4 Induction: Impact of Measured, Free, and Intracellular Perpetrator Concentrations from Human Hepatocyte Induction Studies on Drug-Drug Interaction Predictions
      Yongkai Sun, Paresh P. Chothe, Jennifer E. Sager, Hong Tsao, Amanda Moore, Leena Laitinen and Niresh Hariparsad
      Drug Metabolism and Disposition June 2017, 45 (6) 692-705; DOI: https://doi.org/10.1124/dmd.117.075481

D

  1. Diamond, Sharon

    1. You have access
      In Vitro Interactions of Epacadostat and its Major Metabolites with Human Efflux and Uptake Transporters: Implications for Pharmacokinetics and Drug Interactions
      Qiang Zhang, Yan Zhang, Jason Boer, Jack G. Shi, Peidi Hu, Sharon Diamond and Swamy Yeleswaram
      Drug Metabolism and Disposition June 2017, 45 (6) 612-623; DOI: https://doi.org/10.1124/dmd.116.074609
  2. Doshi, Utkarsh

    1. You have access
      Human Enterocytes as an In Vitro Model for the Evaluation of Intestinal Drug Metabolism: Characterization of Drug-Metabolizing Enzyme Activities of Cryopreserved Human Enterocytes from Twenty-Four Donors
      Ming-Chih David Ho, Nicholas Ring, Kirsten Amaral, Utkarsh Doshi and Albert P. Li
      Drug Metabolism and Disposition June 2017, 45 (6) 686-691; DOI: https://doi.org/10.1124/dmd.116.074377

E

  1. Ellens, Harma

    1. You have access
      Prediction of the Transporter-Mediated Drug-Drug Interaction Potential of Dabrafenib and Its Major Circulating Metabolites
      Harma Ellens, Marta Johnson, Sarah K. Lawrence, Cory Watson, Liangfu Chen and Lauren E. Richards-Peterson
      Drug Metabolism and Disposition June 2017, 45 (6) 646-656; DOI: https://doi.org/10.1124/dmd.116.073932

G

  1. Gilibili, Ravindranath Reddy

    1. You have access
      Coproporphyrin-I: A Fluorescent, Endogenous Optimal Probe Substrate for ABCC2 (MRP2) Suitable for Vesicle-Based MRP2 Inhibition Assay
      Ravindranath Reddy Gilibili, Sagnik Chatterjee, Pravin Bagul, Kathleen W. Mosure, Bokka Venkata Murali, T. Thanga Mariappan, Sandhya Mandlekar and Yurong Lai
      Drug Metabolism and Disposition June 2017, 45 (6) 604-611; DOI: https://doi.org/10.1124/dmd.116.074740
  2. Goto, Kei

    1. You have access
      Prolactin Upregulates Female-Predominant P450 Gene Expressions and Downregulates Male-Predominant Gene Expressions in Mouse Liver
      Yuya Sato, Yoshikatsu Kaneko, Takamasa Cho, Kei Goto, Tadashi Otsuka, Suguru Yamamoto, Shin Goto, Hiroki Maruyama and Ichiei Narita
      Drug Metabolism and Disposition June 2017, 45 (6) 586-592; DOI: https://doi.org/10.1124/dmd.116.074658
  3. Goto, Shin

    1. You have access
      Prolactin Upregulates Female-Predominant P450 Gene Expressions and Downregulates Male-Predominant Gene Expressions in Mouse Liver
      Yuya Sato, Yoshikatsu Kaneko, Takamasa Cho, Kei Goto, Tadashi Otsuka, Suguru Yamamoto, Shin Goto, Hiroki Maruyama and Ichiei Narita
      Drug Metabolism and Disposition June 2017, 45 (6) 586-592; DOI: https://doi.org/10.1124/dmd.116.074658
  4. Granica, Sebastian

    1. Phase II Conjugates of Urolithins Isolated from Human Urine and Potential Role of <em>β</em>-Glucuronidases in Their Disposition
      You have access
      Phase II Conjugates of Urolithins Isolated from Human Urine and Potential Role of β-Glucuronidases in Their Disposition
      Jakub P. Piwowarski, Iwona Stanisławska, Sebastian Granica, Joanna Stefańska and Anna K. Kiss
      Drug Metabolism and Disposition June 2017, 45 (6) 657-665; DOI: https://doi.org/10.1124/dmd.117.075200
  5. Guo, Zitao

    1. You have access
      Increased Plasma Exposures of Conjugated Metabolites of Morinidazole in Renal Failure Patients: A Critical Role of Uremic Toxins
      Fandi Kong, Xiaoyan Pang, Kan Zhong, Zitao Guo, Xiuli Li, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition June 2017, 45 (6) 593-603; DOI: https://doi.org/10.1124/dmd.116.074492

H

  1. Hariparsad, Niresh

    1. You have access
      Quantitative Prediction of CYP3A4 Induction: Impact of Measured, Free, and Intracellular Perpetrator Concentrations from Human Hepatocyte Induction Studies on Drug-Drug Interaction Predictions
      Yongkai Sun, Paresh P. Chothe, Jennifer E. Sager, Hong Tsao, Amanda Moore, Leena Laitinen and Niresh Hariparsad
      Drug Metabolism and Disposition June 2017, 45 (6) 692-705; DOI: https://doi.org/10.1124/dmd.117.075481
  2. Ho, Ming-Chih David

    1. You have access
      Human Enterocytes as an In Vitro Model for the Evaluation of Intestinal Drug Metabolism: Characterization of Drug-Metabolizing Enzyme Activities of Cryopreserved Human Enterocytes from Twenty-Four Donors
      Ming-Chih David Ho, Nicholas Ring, Kirsten Amaral, Utkarsh Doshi and Albert P. Li
      Drug Metabolism and Disposition June 2017, 45 (6) 686-691; DOI: https://doi.org/10.1124/dmd.116.074377
  3. Hu, Ming

    1. High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      You have access
      High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      Jiamei Chen, Lijun Zhu, Xiaoyan Li, Haihui Zheng, Tongmeng Yan, Cong Xie, Sijing Zeng, Jia Yu, Huangyu Jiang, Linlin Lu, Xiaoxiao Qi, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition June 2017, 45 (6) 624-634; DOI: https://doi.org/10.1124/dmd.116.074682
  4. Hu, Peidi

    1. You have access
      In Vitro Interactions of Epacadostat and its Major Metabolites with Human Efflux and Uptake Transporters: Implications for Pharmacokinetics and Drug Interactions
      Qiang Zhang, Yan Zhang, Jason Boer, Jack G. Shi, Peidi Hu, Sharon Diamond and Swamy Yeleswaram
      Drug Metabolism and Disposition June 2017, 45 (6) 612-623; DOI: https://doi.org/10.1124/dmd.116.074609

I

  1. Iyer, Ramaswamy

    1. You have access
      Metabolite Identification, Reaction Phenotyping, and Retrospective Drug-Drug Interaction Predictions of 17-Deacetylnorgestimate, the Active Component of the Oral Contraceptive Norgestimate
      Deepak Ahire, Sarmistha Sinha, Barry Brock, Ramaswamy Iyer, Sandhya Mandlekar and Murali Subramanian
      Drug Metabolism and Disposition June 2017, 45 (6) 676-685; DOI: https://doi.org/10.1124/dmd.116.073940

J

  1. Jiang, Huangyu

    1. High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      You have access
      High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      Jiamei Chen, Lijun Zhu, Xiaoyan Li, Haihui Zheng, Tongmeng Yan, Cong Xie, Sijing Zeng, Jia Yu, Huangyu Jiang, Linlin Lu, Xiaoxiao Qi, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition June 2017, 45 (6) 624-634; DOI: https://doi.org/10.1124/dmd.116.074682
  2. Johnson, Marta

    1. You have access
      Prediction of the Transporter-Mediated Drug-Drug Interaction Potential of Dabrafenib and Its Major Circulating Metabolites
      Harma Ellens, Marta Johnson, Sarah K. Lawrence, Cory Watson, Liangfu Chen and Lauren E. Richards-Peterson
      Drug Metabolism and Disposition June 2017, 45 (6) 646-656; DOI: https://doi.org/10.1124/dmd.116.073932

K

  1. Kaneko, Yoshikatsu

    1. You have access
      Prolactin Upregulates Female-Predominant P450 Gene Expressions and Downregulates Male-Predominant Gene Expressions in Mouse Liver
      Yuya Sato, Yoshikatsu Kaneko, Takamasa Cho, Kei Goto, Tadashi Otsuka, Suguru Yamamoto, Shin Goto, Hiroki Maruyama and Ichiei Narita
      Drug Metabolism and Disposition June 2017, 45 (6) 586-592; DOI: https://doi.org/10.1124/dmd.116.074658
  2. Kiss, Anna K.

    1. Phase II Conjugates of Urolithins Isolated from Human Urine and Potential Role of <em>β</em>-Glucuronidases in Their Disposition
      You have access
      Phase II Conjugates of Urolithins Isolated from Human Urine and Potential Role of β-Glucuronidases in Their Disposition
      Jakub P. Piwowarski, Iwona Stanisławska, Sebastian Granica, Joanna Stefańska and Anna K. Kiss
      Drug Metabolism and Disposition June 2017, 45 (6) 657-665; DOI: https://doi.org/10.1124/dmd.117.075200
  3. Kong, Fandi

    1. You have access
      Increased Plasma Exposures of Conjugated Metabolites of Morinidazole in Renal Failure Patients: A Critical Role of Uremic Toxins
      Fandi Kong, Xiaoyan Pang, Kan Zhong, Zitao Guo, Xiuli Li, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition June 2017, 45 (6) 593-603; DOI: https://doi.org/10.1124/dmd.116.074492

L

  1. Lai, Yurong

    1. You have access
      Coproporphyrin-I: A Fluorescent, Endogenous Optimal Probe Substrate for ABCC2 (MRP2) Suitable for Vesicle-Based MRP2 Inhibition Assay
      Ravindranath Reddy Gilibili, Sagnik Chatterjee, Pravin Bagul, Kathleen W. Mosure, Bokka Venkata Murali, T. Thanga Mariappan, Sandhya Mandlekar and Yurong Lai
      Drug Metabolism and Disposition June 2017, 45 (6) 604-611; DOI: https://doi.org/10.1124/dmd.116.074740
  2. Laitinen, Leena

    1. You have access
      Quantitative Prediction of CYP3A4 Induction: Impact of Measured, Free, and Intracellular Perpetrator Concentrations from Human Hepatocyte Induction Studies on Drug-Drug Interaction Predictions
      Yongkai Sun, Paresh P. Chothe, Jennifer E. Sager, Hong Tsao, Amanda Moore, Leena Laitinen and Niresh Hariparsad
      Drug Metabolism and Disposition June 2017, 45 (6) 692-705; DOI: https://doi.org/10.1124/dmd.117.075481
  3. Lanucara, Francesco

    1. You have access
      Global Proteomic Analysis of Human Liver Microsomes: Rapid Characterization and Quantification of Hepatic Drug-Metabolizing Enzymes
      Brahim Achour, Hajar Al Feteisi, Francesco Lanucara, Amin Rostami-Hodjegan and Jill Barber
      Drug Metabolism and Disposition June 2017, 45 (6) 666-675; DOI: https://doi.org/10.1124/dmd.116.074732
  4. Lawrence, Sarah K.

    1. You have access
      Prediction of the Transporter-Mediated Drug-Drug Interaction Potential of Dabrafenib and Its Major Circulating Metabolites
      Harma Ellens, Marta Johnson, Sarah K. Lawrence, Cory Watson, Liangfu Chen and Lauren E. Richards-Peterson
      Drug Metabolism and Disposition June 2017, 45 (6) 646-656; DOI: https://doi.org/10.1124/dmd.116.073932
  5. Li, Albert P.

    1. You have access
      Human Enterocytes as an In Vitro Model for the Evaluation of Intestinal Drug Metabolism: Characterization of Drug-Metabolizing Enzyme Activities of Cryopreserved Human Enterocytes from Twenty-Four Donors
      Ming-Chih David Ho, Nicholas Ring, Kirsten Amaral, Utkarsh Doshi and Albert P. Li
      Drug Metabolism and Disposition June 2017, 45 (6) 686-691; DOI: https://doi.org/10.1124/dmd.116.074377
  6. Li, Xiaoyan

    1. High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      You have access
      High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      Jiamei Chen, Lijun Zhu, Xiaoyan Li, Haihui Zheng, Tongmeng Yan, Cong Xie, Sijing Zeng, Jia Yu, Huangyu Jiang, Linlin Lu, Xiaoxiao Qi, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition June 2017, 45 (6) 624-634; DOI: https://doi.org/10.1124/dmd.116.074682
  7. Li, Xiuli

    1. You have access
      Increased Plasma Exposures of Conjugated Metabolites of Morinidazole in Renal Failure Patients: A Critical Role of Uremic Toxins
      Fandi Kong, Xiaoyan Pang, Kan Zhong, Zitao Guo, Xiuli Li, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition June 2017, 45 (6) 593-603; DOI: https://doi.org/10.1124/dmd.116.074492
  8. Liu, Zhongqiu

    1. High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      You have access
      High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      Jiamei Chen, Lijun Zhu, Xiaoyan Li, Haihui Zheng, Tongmeng Yan, Cong Xie, Sijing Zeng, Jia Yu, Huangyu Jiang, Linlin Lu, Xiaoxiao Qi, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition June 2017, 45 (6) 624-634; DOI: https://doi.org/10.1124/dmd.116.074682
  9. Lu, Linlin

    1. High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      You have access
      High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      Jiamei Chen, Lijun Zhu, Xiaoyan Li, Haihui Zheng, Tongmeng Yan, Cong Xie, Sijing Zeng, Jia Yu, Huangyu Jiang, Linlin Lu, Xiaoxiao Qi, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition June 2017, 45 (6) 624-634; DOI: https://doi.org/10.1124/dmd.116.074682

M

  1. Mandlekar, Sandhya

    1. You have access
      Coproporphyrin-I: A Fluorescent, Endogenous Optimal Probe Substrate for ABCC2 (MRP2) Suitable for Vesicle-Based MRP2 Inhibition Assay
      Ravindranath Reddy Gilibili, Sagnik Chatterjee, Pravin Bagul, Kathleen W. Mosure, Bokka Venkata Murali, T. Thanga Mariappan, Sandhya Mandlekar and Yurong Lai
      Drug Metabolism and Disposition June 2017, 45 (6) 604-611; DOI: https://doi.org/10.1124/dmd.116.074740
    2. You have access
      Metabolite Identification, Reaction Phenotyping, and Retrospective Drug-Drug Interaction Predictions of 17-Deacetylnorgestimate, the Active Component of the Oral Contraceptive Norgestimate
      Deepak Ahire, Sarmistha Sinha, Barry Brock, Ramaswamy Iyer, Sandhya Mandlekar and Murali Subramanian
      Drug Metabolism and Disposition June 2017, 45 (6) 676-685; DOI: https://doi.org/10.1124/dmd.116.073940
  2. Mariappan, T. Thanga

    1. You have access
      Coproporphyrin-I: A Fluorescent, Endogenous Optimal Probe Substrate for ABCC2 (MRP2) Suitable for Vesicle-Based MRP2 Inhibition Assay
      Ravindranath Reddy Gilibili, Sagnik Chatterjee, Pravin Bagul, Kathleen W. Mosure, Bokka Venkata Murali, T. Thanga Mariappan, Sandhya Mandlekar and Yurong Lai
      Drug Metabolism and Disposition June 2017, 45 (6) 604-611; DOI: https://doi.org/10.1124/dmd.116.074740
  3. Maruyama, Hiroki

    1. You have access
      Prolactin Upregulates Female-Predominant P450 Gene Expressions and Downregulates Male-Predominant Gene Expressions in Mouse Liver
      Yuya Sato, Yoshikatsu Kaneko, Takamasa Cho, Kei Goto, Tadashi Otsuka, Suguru Yamamoto, Shin Goto, Hiroki Maruyama and Ichiei Narita
      Drug Metabolism and Disposition June 2017, 45 (6) 586-592; DOI: https://doi.org/10.1124/dmd.116.074658
  4. Moore, Amanda

    1. You have access
      Quantitative Prediction of CYP3A4 Induction: Impact of Measured, Free, and Intracellular Perpetrator Concentrations from Human Hepatocyte Induction Studies on Drug-Drug Interaction Predictions
      Yongkai Sun, Paresh P. Chothe, Jennifer E. Sager, Hong Tsao, Amanda Moore, Leena Laitinen and Niresh Hariparsad
      Drug Metabolism and Disposition June 2017, 45 (6) 692-705; DOI: https://doi.org/10.1124/dmd.117.075481
  5. Mosure, Kathleen W.

    1. You have access
      Coproporphyrin-I: A Fluorescent, Endogenous Optimal Probe Substrate for ABCC2 (MRP2) Suitable for Vesicle-Based MRP2 Inhibition Assay
      Ravindranath Reddy Gilibili, Sagnik Chatterjee, Pravin Bagul, Kathleen W. Mosure, Bokka Venkata Murali, T. Thanga Mariappan, Sandhya Mandlekar and Yurong Lai
      Drug Metabolism and Disposition June 2017, 45 (6) 604-611; DOI: https://doi.org/10.1124/dmd.116.074740
  6. Murali, Bokka Venkata

    1. You have access
      Coproporphyrin-I: A Fluorescent, Endogenous Optimal Probe Substrate for ABCC2 (MRP2) Suitable for Vesicle-Based MRP2 Inhibition Assay
      Ravindranath Reddy Gilibili, Sagnik Chatterjee, Pravin Bagul, Kathleen W. Mosure, Bokka Venkata Murali, T. Thanga Mariappan, Sandhya Mandlekar and Yurong Lai
      Drug Metabolism and Disposition June 2017, 45 (6) 604-611; DOI: https://doi.org/10.1124/dmd.116.074740

N

  1. Narita, Ichiei

    1. You have access
      Prolactin Upregulates Female-Predominant P450 Gene Expressions and Downregulates Male-Predominant Gene Expressions in Mouse Liver
      Yuya Sato, Yoshikatsu Kaneko, Takamasa Cho, Kei Goto, Tadashi Otsuka, Suguru Yamamoto, Shin Goto, Hiroki Maruyama and Ichiei Narita
      Drug Metabolism and Disposition June 2017, 45 (6) 586-592; DOI: https://doi.org/10.1124/dmd.116.074658

O

  1. Otsuka, Tadashi

    1. You have access
      Prolactin Upregulates Female-Predominant P450 Gene Expressions and Downregulates Male-Predominant Gene Expressions in Mouse Liver
      Yuya Sato, Yoshikatsu Kaneko, Takamasa Cho, Kei Goto, Tadashi Otsuka, Suguru Yamamoto, Shin Goto, Hiroki Maruyama and Ichiei Narita
      Drug Metabolism and Disposition June 2017, 45 (6) 586-592; DOI: https://doi.org/10.1124/dmd.116.074658

P

  1. Pang, Xiaoyan

    1. You have access
      Increased Plasma Exposures of Conjugated Metabolites of Morinidazole in Renal Failure Patients: A Critical Role of Uremic Toxins
      Fandi Kong, Xiaoyan Pang, Kan Zhong, Zitao Guo, Xiuli Li, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition June 2017, 45 (6) 593-603; DOI: https://doi.org/10.1124/dmd.116.074492
  2. Petrunak, Elyse M.

    1. Structural and Functional Evaluation of Clinically Relevant Inhibitors of Steroidogenic Cytochrome P450 17A1
      You have access
      Structural and Functional Evaluation of Clinically Relevant Inhibitors of Steroidogenic Cytochrome P450 17A1
      Elyse M. Petrunak, Steven A. Rogers, Jeffrey Aubé and Emily E. Scott
      Drug Metabolism and Disposition June 2017, 45 (6) 635-645; DOI: https://doi.org/10.1124/dmd.117.075317
  3. Piwowarski, Jakub P.

    1. Phase II Conjugates of Urolithins Isolated from Human Urine and Potential Role of <em>β</em>-Glucuronidases in Their Disposition
      You have access
      Phase II Conjugates of Urolithins Isolated from Human Urine and Potential Role of β-Glucuronidases in Their Disposition
      Jakub P. Piwowarski, Iwona Stanisławska, Sebastian Granica, Joanna Stefańska and Anna K. Kiss
      Drug Metabolism and Disposition June 2017, 45 (6) 657-665; DOI: https://doi.org/10.1124/dmd.117.075200

Q

  1. Qi, Xiaoxiao

    1. High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      You have access
      High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      Jiamei Chen, Lijun Zhu, Xiaoyan Li, Haihui Zheng, Tongmeng Yan, Cong Xie, Sijing Zeng, Jia Yu, Huangyu Jiang, Linlin Lu, Xiaoxiao Qi, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition June 2017, 45 (6) 624-634; DOI: https://doi.org/10.1124/dmd.116.074682

R

  1. Richards-Peterson, Lauren E.

    1. You have access
      Prediction of the Transporter-Mediated Drug-Drug Interaction Potential of Dabrafenib and Its Major Circulating Metabolites
      Harma Ellens, Marta Johnson, Sarah K. Lawrence, Cory Watson, Liangfu Chen and Lauren E. Richards-Peterson
      Drug Metabolism and Disposition June 2017, 45 (6) 646-656; DOI: https://doi.org/10.1124/dmd.116.073932
  2. Ring, Nicholas

    1. You have access
      Human Enterocytes as an In Vitro Model for the Evaluation of Intestinal Drug Metabolism: Characterization of Drug-Metabolizing Enzyme Activities of Cryopreserved Human Enterocytes from Twenty-Four Donors
      Ming-Chih David Ho, Nicholas Ring, Kirsten Amaral, Utkarsh Doshi and Albert P. Li
      Drug Metabolism and Disposition June 2017, 45 (6) 686-691; DOI: https://doi.org/10.1124/dmd.116.074377
  3. Rogers, Steven A.

    1. Structural and Functional Evaluation of Clinically Relevant Inhibitors of Steroidogenic Cytochrome P450 17A1
      You have access
      Structural and Functional Evaluation of Clinically Relevant Inhibitors of Steroidogenic Cytochrome P450 17A1
      Elyse M. Petrunak, Steven A. Rogers, Jeffrey Aubé and Emily E. Scott
      Drug Metabolism and Disposition June 2017, 45 (6) 635-645; DOI: https://doi.org/10.1124/dmd.117.075317
  4. Rostami-Hodjegan, Amin

    1. You have access
      Global Proteomic Analysis of Human Liver Microsomes: Rapid Characterization and Quantification of Hepatic Drug-Metabolizing Enzymes
      Brahim Achour, Hajar Al Feteisi, Francesco Lanucara, Amin Rostami-Hodjegan and Jill Barber
      Drug Metabolism and Disposition June 2017, 45 (6) 666-675; DOI: https://doi.org/10.1124/dmd.116.074732

S

  1. Sager, Jennifer E.

    1. You have access
      Quantitative Prediction of CYP3A4 Induction: Impact of Measured, Free, and Intracellular Perpetrator Concentrations from Human Hepatocyte Induction Studies on Drug-Drug Interaction Predictions
      Yongkai Sun, Paresh P. Chothe, Jennifer E. Sager, Hong Tsao, Amanda Moore, Leena Laitinen and Niresh Hariparsad
      Drug Metabolism and Disposition June 2017, 45 (6) 692-705; DOI: https://doi.org/10.1124/dmd.117.075481
  2. Sato, Yuya

    1. You have access
      Prolactin Upregulates Female-Predominant P450 Gene Expressions and Downregulates Male-Predominant Gene Expressions in Mouse Liver
      Yuya Sato, Yoshikatsu Kaneko, Takamasa Cho, Kei Goto, Tadashi Otsuka, Suguru Yamamoto, Shin Goto, Hiroki Maruyama and Ichiei Narita
      Drug Metabolism and Disposition June 2017, 45 (6) 586-592; DOI: https://doi.org/10.1124/dmd.116.074658
  3. Scott, Emily E.

    1. Structural and Functional Evaluation of Clinically Relevant Inhibitors of Steroidogenic Cytochrome P450 17A1
      You have access
      Structural and Functional Evaluation of Clinically Relevant Inhibitors of Steroidogenic Cytochrome P450 17A1
      Elyse M. Petrunak, Steven A. Rogers, Jeffrey Aubé and Emily E. Scott
      Drug Metabolism and Disposition June 2017, 45 (6) 635-645; DOI: https://doi.org/10.1124/dmd.117.075317
  4. Shahidi-Latham, Sheerin K.

    1. You have access
      Applying Stable Isotope Labeled Amino Acids in Micropatterned Hepatocyte Coculture to Directly Determine the Degradation Rate Constant for CYP3A4
      Ryan H. Takahashi, Sheerin K. Shahidi-Latham, Susan Wong and Jae H. Chang
      Drug Metabolism and Disposition June 2017, 45 (6) 581-585; DOI: https://doi.org/10.1124/dmd.116.074393
  5. Shi, Jack G.

    1. You have access
      In Vitro Interactions of Epacadostat and its Major Metabolites with Human Efflux and Uptake Transporters: Implications for Pharmacokinetics and Drug Interactions
      Qiang Zhang, Yan Zhang, Jason Boer, Jack G. Shi, Peidi Hu, Sharon Diamond and Swamy Yeleswaram
      Drug Metabolism and Disposition June 2017, 45 (6) 612-623; DOI: https://doi.org/10.1124/dmd.116.074609
  6. Sinha, Sarmistha

    1. You have access
      Metabolite Identification, Reaction Phenotyping, and Retrospective Drug-Drug Interaction Predictions of 17-Deacetylnorgestimate, the Active Component of the Oral Contraceptive Norgestimate
      Deepak Ahire, Sarmistha Sinha, Barry Brock, Ramaswamy Iyer, Sandhya Mandlekar and Murali Subramanian
      Drug Metabolism and Disposition June 2017, 45 (6) 676-685; DOI: https://doi.org/10.1124/dmd.116.073940
  7. Stanisławska, Iwona

    1. Phase II Conjugates of Urolithins Isolated from Human Urine and Potential Role of <em>β</em>-Glucuronidases in Their Disposition
      You have access
      Phase II Conjugates of Urolithins Isolated from Human Urine and Potential Role of β-Glucuronidases in Their Disposition
      Jakub P. Piwowarski, Iwona Stanisławska, Sebastian Granica, Joanna Stefańska and Anna K. Kiss
      Drug Metabolism and Disposition June 2017, 45 (6) 657-665; DOI: https://doi.org/10.1124/dmd.117.075200
  8. Stefańska, Joanna

    1. Phase II Conjugates of Urolithins Isolated from Human Urine and Potential Role of <em>β</em>-Glucuronidases in Their Disposition
      You have access
      Phase II Conjugates of Urolithins Isolated from Human Urine and Potential Role of β-Glucuronidases in Their Disposition
      Jakub P. Piwowarski, Iwona Stanisławska, Sebastian Granica, Joanna Stefańska and Anna K. Kiss
      Drug Metabolism and Disposition June 2017, 45 (6) 657-665; DOI: https://doi.org/10.1124/dmd.117.075200
  9. Subramanian, Murali

    1. You have access
      Metabolite Identification, Reaction Phenotyping, and Retrospective Drug-Drug Interaction Predictions of 17-Deacetylnorgestimate, the Active Component of the Oral Contraceptive Norgestimate
      Deepak Ahire, Sarmistha Sinha, Barry Brock, Ramaswamy Iyer, Sandhya Mandlekar and Murali Subramanian
      Drug Metabolism and Disposition June 2017, 45 (6) 676-685; DOI: https://doi.org/10.1124/dmd.116.073940
  10. Sun, Yongkai

    1. You have access
      Quantitative Prediction of CYP3A4 Induction: Impact of Measured, Free, and Intracellular Perpetrator Concentrations from Human Hepatocyte Induction Studies on Drug-Drug Interaction Predictions
      Yongkai Sun, Paresh P. Chothe, Jennifer E. Sager, Hong Tsao, Amanda Moore, Leena Laitinen and Niresh Hariparsad
      Drug Metabolism and Disposition June 2017, 45 (6) 692-705; DOI: https://doi.org/10.1124/dmd.117.075481

T

  1. Takahashi, Ryan H.

    1. You have access
      Applying Stable Isotope Labeled Amino Acids in Micropatterned Hepatocyte Coculture to Directly Determine the Degradation Rate Constant for CYP3A4
      Ryan H. Takahashi, Sheerin K. Shahidi-Latham, Susan Wong and Jae H. Chang
      Drug Metabolism and Disposition June 2017, 45 (6) 581-585; DOI: https://doi.org/10.1124/dmd.116.074393
  2. Tsao, Hong

    1. You have access
      Quantitative Prediction of CYP3A4 Induction: Impact of Measured, Free, and Intracellular Perpetrator Concentrations from Human Hepatocyte Induction Studies on Drug-Drug Interaction Predictions
      Yongkai Sun, Paresh P. Chothe, Jennifer E. Sager, Hong Tsao, Amanda Moore, Leena Laitinen and Niresh Hariparsad
      Drug Metabolism and Disposition June 2017, 45 (6) 692-705; DOI: https://doi.org/10.1124/dmd.117.075481

W

  1. Wang, Ying

    1. High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      You have access
      High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      Jiamei Chen, Lijun Zhu, Xiaoyan Li, Haihui Zheng, Tongmeng Yan, Cong Xie, Sijing Zeng, Jia Yu, Huangyu Jiang, Linlin Lu, Xiaoxiao Qi, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition June 2017, 45 (6) 624-634; DOI: https://doi.org/10.1124/dmd.116.074682
  2. Watson, Cory

    1. You have access
      Prediction of the Transporter-Mediated Drug-Drug Interaction Potential of Dabrafenib and Its Major Circulating Metabolites
      Harma Ellens, Marta Johnson, Sarah K. Lawrence, Cory Watson, Liangfu Chen and Lauren E. Richards-Peterson
      Drug Metabolism and Disposition June 2017, 45 (6) 646-656; DOI: https://doi.org/10.1124/dmd.116.073932
  3. Wong, Susan

    1. You have access
      Applying Stable Isotope Labeled Amino Acids in Micropatterned Hepatocyte Coculture to Directly Determine the Degradation Rate Constant for CYP3A4
      Ryan H. Takahashi, Sheerin K. Shahidi-Latham, Susan Wong and Jae H. Chang
      Drug Metabolism and Disposition June 2017, 45 (6) 581-585; DOI: https://doi.org/10.1124/dmd.116.074393

X

  1. Xie, Cong

    1. High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      You have access
      High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      Jiamei Chen, Lijun Zhu, Xiaoyan Li, Haihui Zheng, Tongmeng Yan, Cong Xie, Sijing Zeng, Jia Yu, Huangyu Jiang, Linlin Lu, Xiaoxiao Qi, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition June 2017, 45 (6) 624-634; DOI: https://doi.org/10.1124/dmd.116.074682

Y

  1. Yamamoto, Suguru

    1. You have access
      Prolactin Upregulates Female-Predominant P450 Gene Expressions and Downregulates Male-Predominant Gene Expressions in Mouse Liver
      Yuya Sato, Yoshikatsu Kaneko, Takamasa Cho, Kei Goto, Tadashi Otsuka, Suguru Yamamoto, Shin Goto, Hiroki Maruyama and Ichiei Narita
      Drug Metabolism and Disposition June 2017, 45 (6) 586-592; DOI: https://doi.org/10.1124/dmd.116.074658
  2. Yan, Tongmeng

    1. High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      You have access
      High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      Jiamei Chen, Lijun Zhu, Xiaoyan Li, Haihui Zheng, Tongmeng Yan, Cong Xie, Sijing Zeng, Jia Yu, Huangyu Jiang, Linlin Lu, Xiaoxiao Qi, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition June 2017, 45 (6) 624-634; DOI: https://doi.org/10.1124/dmd.116.074682
  3. Yeleswaram, Swamy

    1. You have access
      In Vitro Interactions of Epacadostat and its Major Metabolites with Human Efflux and Uptake Transporters: Implications for Pharmacokinetics and Drug Interactions
      Qiang Zhang, Yan Zhang, Jason Boer, Jack G. Shi, Peidi Hu, Sharon Diamond and Swamy Yeleswaram
      Drug Metabolism and Disposition June 2017, 45 (6) 612-623; DOI: https://doi.org/10.1124/dmd.116.074609
  4. Yu, Jia

    1. High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      You have access
      High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      Jiamei Chen, Lijun Zhu, Xiaoyan Li, Haihui Zheng, Tongmeng Yan, Cong Xie, Sijing Zeng, Jia Yu, Huangyu Jiang, Linlin Lu, Xiaoxiao Qi, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition June 2017, 45 (6) 624-634; DOI: https://doi.org/10.1124/dmd.116.074682

Z

  1. Zeng, Sijing

    1. High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      You have access
      High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      Jiamei Chen, Lijun Zhu, Xiaoyan Li, Haihui Zheng, Tongmeng Yan, Cong Xie, Sijing Zeng, Jia Yu, Huangyu Jiang, Linlin Lu, Xiaoxiao Qi, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition June 2017, 45 (6) 624-634; DOI: https://doi.org/10.1124/dmd.116.074682
  2. Zhang, Qiang

    1. You have access
      In Vitro Interactions of Epacadostat and its Major Metabolites with Human Efflux and Uptake Transporters: Implications for Pharmacokinetics and Drug Interactions
      Qiang Zhang, Yan Zhang, Jason Boer, Jack G. Shi, Peidi Hu, Sharon Diamond and Swamy Yeleswaram
      Drug Metabolism and Disposition June 2017, 45 (6) 612-623; DOI: https://doi.org/10.1124/dmd.116.074609
  3. Zhang, Yan

    1. You have access
      In Vitro Interactions of Epacadostat and its Major Metabolites with Human Efflux and Uptake Transporters: Implications for Pharmacokinetics and Drug Interactions
      Qiang Zhang, Yan Zhang, Jason Boer, Jack G. Shi, Peidi Hu, Sharon Diamond and Swamy Yeleswaram
      Drug Metabolism and Disposition June 2017, 45 (6) 612-623; DOI: https://doi.org/10.1124/dmd.116.074609
  4. Zheng, Haihui

    1. High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      You have access
      High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      Jiamei Chen, Lijun Zhu, Xiaoyan Li, Haihui Zheng, Tongmeng Yan, Cong Xie, Sijing Zeng, Jia Yu, Huangyu Jiang, Linlin Lu, Xiaoxiao Qi, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition June 2017, 45 (6) 624-634; DOI: https://doi.org/10.1124/dmd.116.074682
  5. Zhong, Dafang

    1. You have access
      Increased Plasma Exposures of Conjugated Metabolites of Morinidazole in Renal Failure Patients: A Critical Role of Uremic Toxins
      Fandi Kong, Xiaoyan Pang, Kan Zhong, Zitao Guo, Xiuli Li, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition June 2017, 45 (6) 593-603; DOI: https://doi.org/10.1124/dmd.116.074492
  6. Zhong, Kan

    1. You have access
      Increased Plasma Exposures of Conjugated Metabolites of Morinidazole in Renal Failure Patients: A Critical Role of Uremic Toxins
      Fandi Kong, Xiaoyan Pang, Kan Zhong, Zitao Guo, Xiuli Li, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition June 2017, 45 (6) 593-603; DOI: https://doi.org/10.1124/dmd.116.074492
  7. Zhu, Lijun

    1. High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      You have access
      High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences
      Jiamei Chen, Lijun Zhu, Xiaoyan Li, Haihui Zheng, Tongmeng Yan, Cong Xie, Sijing Zeng, Jia Yu, Huangyu Jiang, Linlin Lu, Xiaoxiao Qi, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition June 2017, 45 (6) 624-634; DOI: https://doi.org/10.1124/dmd.116.074682
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Drug Metabolism and Disposition: 45 (6)
Drug Metabolism and Disposition
Vol. 45, Issue 6
1 Jun 2017
  • Table of Contents
  • Table of Contents (PDF)
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
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