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Research ArticleArticle

Structural and Functional Evaluation of Clinically Relevant Inhibitors of Steroidogenic Cytochrome P450 17A1

Elyse M. Petrunak, Steven A. Rogers, Jeffrey Aubé and Emily E. Scott
Drug Metabolism and Disposition June 2017, 45 (6) 635-645; DOI: https://doi.org/10.1124/dmd.117.075317
Elyse M. Petrunak
Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas
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Steven A. Rogers
Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas
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Jeffrey Aubé
Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas
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Emily E. Scott
Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas
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Article Information

vol. 45 no. 6 635-645
DOI 
https://doi.org/10.1124/dmd.117.075317
PubMed 
28373265

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received January 30, 2017
  • Accepted March 31, 2017
  • Published online May 4, 2017.

Article Versions

  • Earlier version (April 3, 2017 - 09:39).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2017 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Elyse M. Petrunak1,
  2. Steven A. Rogers2,
  3. Jeffrey Aubé3, and
  4. Emily E. Scott4
  1. Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas
  1. Address correspondence to:
    Emily E. Scott, Department of Medicinal Chemistry, University of Michigan, 428 Church Street, Ann Arbor, MI 48109. E-mail: scottee{at}umich.edu
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Drug Metabolism and Disposition: 45 (6)
Drug Metabolism and Disposition
Vol. 45, Issue 6
1 Jun 2017
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Research ArticleArticle

Structure and Function of Cytochrome P450 17A1 Inhibitors

Elyse M. Petrunak, Steven A. Rogers, Jeffrey Aubé and Emily E. Scott
Drug Metabolism and Disposition June 1, 2017, 45 (6) 635-645; DOI: https://doi.org/10.1124/dmd.117.075317

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Research ArticleArticle

Structure and Function of Cytochrome P450 17A1 Inhibitors

Elyse M. Petrunak, Steven A. Rogers, Jeffrey Aubé and Emily E. Scott
Drug Metabolism and Disposition June 1, 2017, 45 (6) 635-645; DOI: https://doi.org/10.1124/dmd.117.075317
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