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Research ArticleArticle

Global Proteomic Analysis of Human Liver Microsomes: Rapid Characterization and Quantification of Hepatic Drug-Metabolizing Enzymes

Brahim Achour, Hajar Al Feteisi, Francesco Lanucara, Amin Rostami-Hodjegan and Jill Barber
Drug Metabolism and Disposition June 2017, 45 (6) 666-675; DOI: https://doi.org/10.1124/dmd.116.074732
Brahim Achour
Centre for Applied Pharmacokinetic Research, Division of Pharmacy and Optometry, School of Health Sciences, University of Manchester, Manchester (B.A., H.A.F., A.R.-H., J.B.), Waters Corporation, Wilmslow, Cheshire East (F.L.), and Simcyp Limited (a Certara Company), Blades Enterprise Centre, Sheffield (A.R.-H.), United Kingdom
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Hajar Al Feteisi
Centre for Applied Pharmacokinetic Research, Division of Pharmacy and Optometry, School of Health Sciences, University of Manchester, Manchester (B.A., H.A.F., A.R.-H., J.B.), Waters Corporation, Wilmslow, Cheshire East (F.L.), and Simcyp Limited (a Certara Company), Blades Enterprise Centre, Sheffield (A.R.-H.), United Kingdom
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Francesco Lanucara
Centre for Applied Pharmacokinetic Research, Division of Pharmacy and Optometry, School of Health Sciences, University of Manchester, Manchester (B.A., H.A.F., A.R.-H., J.B.), Waters Corporation, Wilmslow, Cheshire East (F.L.), and Simcyp Limited (a Certara Company), Blades Enterprise Centre, Sheffield (A.R.-H.), United Kingdom
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Amin Rostami-Hodjegan
Centre for Applied Pharmacokinetic Research, Division of Pharmacy and Optometry, School of Health Sciences, University of Manchester, Manchester (B.A., H.A.F., A.R.-H., J.B.), Waters Corporation, Wilmslow, Cheshire East (F.L.), and Simcyp Limited (a Certara Company), Blades Enterprise Centre, Sheffield (A.R.-H.), United Kingdom
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Jill Barber
Centre for Applied Pharmacokinetic Research, Division of Pharmacy and Optometry, School of Health Sciences, University of Manchester, Manchester (B.A., H.A.F., A.R.-H., J.B.), Waters Corporation, Wilmslow, Cheshire East (F.L.), and Simcyp Limited (a Certara Company), Blades Enterprise Centre, Sheffield (A.R.-H.), United Kingdom
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Article Information

vol. 45 no. 6 666-675
DOI 
https://doi.org/10.1124/dmd.116.074732
PubMed 
28373266

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received December 19, 2016
  • Accepted March 30, 2017
  • Published online May 11, 2017.

Article Versions

  • Earlier version (April 3, 2017 - 09:39).
  • Earlier version (April 3, 2017 - 11:06).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2017 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Brahim Achour,
  2. Hajar Al Feteisi,
  3. Francesco Lanucara,
  4. Amin Rostami-Hodjegan, and
  5. Jill Barber
  1. Centre for Applied Pharmacokinetic Research, Division of Pharmacy and Optometry, School of Health Sciences, University of Manchester, Manchester (B.A., H.A.F., A.R.-H., J.B.), Waters Corporation, Wilmslow, Cheshire East (F.L.), and Simcyp Limited (a Certara Company), Blades Enterprise Centre, Sheffield (A.R.-H.), United Kingdom
  1. Address correspondence to:
    Dr. Jill Barber, Division of Pharmacy and Optometry, School of Health Sciences, University of Manchester, Stopford Building, Oxford Road, Manchester, M13 9PT, UK. E-mail: Jill.Barber{at}manchester.ac.uk
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Drug Metabolism and Disposition: 45 (6)
Drug Metabolism and Disposition
Vol. 45, Issue 6
1 Jun 2017
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Research ArticleArticle

Global Analysis of Human Liver Microsomal Subproteome

Brahim Achour, Hajar Al Feteisi, Francesco Lanucara, Amin Rostami-Hodjegan and Jill Barber
Drug Metabolism and Disposition June 1, 2017, 45 (6) 666-675; DOI: https://doi.org/10.1124/dmd.116.074732

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Research ArticleArticle

Global Analysis of Human Liver Microsomal Subproteome

Brahim Achour, Hajar Al Feteisi, Francesco Lanucara, Amin Rostami-Hodjegan and Jill Barber
Drug Metabolism and Disposition June 1, 2017, 45 (6) 666-675; DOI: https://doi.org/10.1124/dmd.116.074732
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