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Research ArticleArticle

Metabolite Identification, Reaction Phenotyping, and Retrospective Drug-Drug Interaction Predictions of 17-Deacetylnorgestimate, the Active Component of the Oral Contraceptive Norgestimate

Deepak Ahire, Sarmistha Sinha, Barry Brock, Ramaswamy Iyer, Sandhya Mandlekar and Murali Subramanian
Drug Metabolism and Disposition June 2017, 45 (6) 676-685; DOI: https://doi.org/10.1124/dmd.116.073940

Article Information

vol. 45 no. 6 676-685
DOI 
https://doi.org/10.1124/dmd.116.073940
PubMed 
28283499
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received October 17, 2016
  • Accepted March 6, 2017
  • Published online May 12, 2017.

Article Versions

Copyright & Usage 
Copyright © 2017 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Deepak Ahire1,
  2. Sarmistha Sinha1,
  3. Barry Brock,
  4. Ramaswamy Iyer,
  5. Sandhya Mandlekar, and
  6. Murali Subramanian
  1. Pharmaceutical Candidate Optimization, Biocon Bristol-Myers Squibb R&D Center, Syngene International Ltd., Bangalore, India (D.A., S.S., M.S.); Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Pennington, New Jersy (B.B., R.I.); and Pharmaceutical Candidate Optimization, Bristol-Myers Squibb India Ltd., Bangalore, India: (S.M.)
  1. Address correspondence to:
    Murali Subramanian, Biocon Bristol-Myers Squibb Research and Development Center, Syngene International Ltd., Biocon Park Plot 2 & 3 Bommasandra IV Phase Bangalore-560 099, India. E-mail: murali.subramanian{at}syngeneintl.com
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Research ArticleArticle

Predicting 17-Deacetylnorgestimate Drug-Drug Interactions

Deepak Ahire, Sarmistha Sinha, Barry Brock, Ramaswamy Iyer, Sandhya Mandlekar and Murali Subramanian
Drug Metabolism and Disposition June 1, 2017, 45 (6) 676-685; DOI: https://doi.org/10.1124/dmd.116.073940
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