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Index by author

August 01, 2017; Volume 45,Issue 8

B

  1. Bao, Xiaochen

    1. Role of CYP2B in Phenobarbital-Induced Hepatocyte Proliferation in Mice
      Lei Li, Xiaochen Bao, Qing-Yu Zhang, Masahiko Negishi and Xinxin Ding
      Drug Metabolism and Disposition August 2017, 45 (8) 977-981; DOI: https://doi.org/10.1124/dmd.117.076406

C

  1. Camenisch, Gian

    1. Open Access
      Comparison of 19F NMR and 14C Measurements for the Assessment of ADME of BYL719 (Alpelisib) in Humans
      Alexander David James, Cyrille Marvalin, Alexandre Luneau, Axel Meissner and Gian Camenisch
      Drug Metabolism and Disposition August 2017, 45 (8) 900-907; DOI: https://doi.org/10.1124/dmd.117.075424

  2. Chen, Weiqi

    1. Comparative Evaluation of Plasma Bile Acids, Dehydroepiandrosterone Sulfate, Hexadecanedioate, and Tetradecanedioate with Coproporphyrins I and III as Markers of OATP Inhibition in Healthy Subjects
      Hong Shen, Weiqi Chen, Dieter M. Drexler, Sandhya Mandlekar, Vinay K. Holenarsipur, Eric E. Shields, Robert Langish, Kurex Sidik, Jinping Gan, W. Griffith Humphreys, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition August 2017, 45 (8) 908-919; DOI: https://doi.org/10.1124/dmd.117.075531

D

  1. Ding, Xinxin

    1. Role of CYP2B in Phenobarbital-Induced Hepatocyte Proliferation in Mice
      Lei Li, Xiaochen Bao, Qing-Yu Zhang, Masahiko Negishi and Xinxin Ding
      Drug Metabolism and Disposition August 2017, 45 (8) 977-981; DOI: https://doi.org/10.1124/dmd.117.076406

  2. Dorr, Casey R.

    1. CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism
      Casey R. Dorr, Rory P. Remmel, Amutha Muthusamy, James Fisher, Branden S. Moriarity, Kazuto Yasuda, Baolin Wu, Weihua Guan, Erin G. Schuetz, William S. Oetting, Pamala A. Jacobson and Ajay K. Israni
      Drug Metabolism and Disposition August 2017, 45 (8) 957-965; DOI: https://doi.org/10.1124/dmd.117.076307

  3. Drexler, Dieter M.

    1. Comparative Evaluation of Plasma Bile Acids, Dehydroepiandrosterone Sulfate, Hexadecanedioate, and Tetradecanedioate with Coproporphyrins I and III as Markers of OATP Inhibition in Healthy Subjects
      Hong Shen, Weiqi Chen, Dieter M. Drexler, Sandhya Mandlekar, Vinay K. Holenarsipur, Eric E. Shields, Robert Langish, Kurex Sidik, Jinping Gan, W. Griffith Humphreys, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition August 2017, 45 (8) 908-919; DOI: https://doi.org/10.1124/dmd.117.075531

E

  1. Ekins, Sean

    1. Rosuvastatin and Atorvastatin Are Ligands of the Human Constitutive Androstane Receptor/Retinoid X Receptor α Complex
      Tadeja Režen, Mateja Hafner, Sandhya Kortagere, Sean Ekins, Vesna Hodnik and Damjana Rozman
      Drug Metabolism and Disposition August 2017, 45 (8) 974-976; DOI: https://doi.org/10.1124/dmd.117.075523

F

  1. Fan, Yunzhou

    1. PKC/Nedd4-2 Signaling Pathway Regulates the Cell Surface Expression of Drug Transporter hOAT1
      Da Xu, Jinghui Zhang, Qiang Zhang, Yunzhou Fan, Chenchang Liu and Guofeng You
      Drug Metabolism and Disposition August 2017, 45 (8) 887-895; DOI: https://doi.org/10.1124/dmd.117.075861

  2. Fisher, James

    1. CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism
      Casey R. Dorr, Rory P. Remmel, Amutha Muthusamy, James Fisher, Branden S. Moriarity, Kazuto Yasuda, Baolin Wu, Weihua Guan, Erin G. Schuetz, William S. Oetting, Pamala A. Jacobson and Ajay K. Israni
      Drug Metabolism and Disposition August 2017, 45 (8) 957-965; DOI: https://doi.org/10.1124/dmd.117.076307

  3. Fredenwall, Marlene

    1. Oxetane Substrates of Human Microsomal Epoxide Hydrolase
      Oxetane Substrates of Human Microsomal Epoxide Hydrolase
      Francesca Toselli, Marlene Fredenwall, Peder Svensson, Xue-Qing Li, Anders Johansson, Lars Weidolf and Martin A. Hayes
      Drug Metabolism and Disposition August 2017, 45 (8) 966-973; DOI: https://doi.org/10.1124/dmd.117.076489

G

  1. Gan, Jinping

    1. Comparative Evaluation of Plasma Bile Acids, Dehydroepiandrosterone Sulfate, Hexadecanedioate, and Tetradecanedioate with Coproporphyrins I and III as Markers of OATP Inhibition in Healthy Subjects
      Hong Shen, Weiqi Chen, Dieter M. Drexler, Sandhya Mandlekar, Vinay K. Holenarsipur, Eric E. Shields, Robert Langish, Kurex Sidik, Jinping Gan, W. Griffith Humphreys, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition August 2017, 45 (8) 908-919; DOI: https://doi.org/10.1124/dmd.117.075531

  2. Gaohua, Lu

    1. Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model I: Insights into Factors that Determine Fetal Drug Exposure through Simulations and Sensitivity Analyses
      Zufei Zhang, Marjorie Z. Imperial, Gabriela I. Patilea-Vrana, Janak Wedagedera, Lu Gaohua and Jashvant D. Unadkat
      Drug Metabolism and Disposition August 2017, 45 (8) 920-938; DOI: https://doi.org/10.1124/dmd.117.075192

  3. Garattini, Enrico

    1. Direct Comparison of the Enzymatic Characteristics and Superoxide Production of the Four Aldehyde Oxidase Enzymes Present in Mouse
      Gökhan Kücükgöze, Mineko Terao, Enrico Garattini and Silke Leimkühler
      Drug Metabolism and Disposition August 2017, 45 (8) 947-955; DOI: https://doi.org/10.1124/dmd.117.075937

  4. Guan, Weihua

    1. CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism
      Casey R. Dorr, Rory P. Remmel, Amutha Muthusamy, James Fisher, Branden S. Moriarity, Kazuto Yasuda, Baolin Wu, Weihua Guan, Erin G. Schuetz, William S. Oetting, Pamala A. Jacobson and Ajay K. Israni
      Drug Metabolism and Disposition August 2017, 45 (8) 957-965; DOI: https://doi.org/10.1124/dmd.117.076307

H

  1. Hafner, Mateja

    1. Rosuvastatin and Atorvastatin Are Ligands of the Human Constitutive Androstane Receptor/Retinoid X Receptor α Complex
      Tadeja Režen, Mateja Hafner, Sandhya Kortagere, Sean Ekins, Vesna Hodnik and Damjana Rozman
      Drug Metabolism and Disposition August 2017, 45 (8) 974-976; DOI: https://doi.org/10.1124/dmd.117.075523

  2. Hayes, Martin A.

    1. Oxetane Substrates of Human Microsomal Epoxide Hydrolase
      Oxetane Substrates of Human Microsomal Epoxide Hydrolase
      Francesca Toselli, Marlene Fredenwall, Peder Svensson, Xue-Qing Li, Anders Johansson, Lars Weidolf and Martin A. Hayes
      Drug Metabolism and Disposition August 2017, 45 (8) 966-973; DOI: https://doi.org/10.1124/dmd.117.076489

  3. Hodnik, Vesna

    1. Rosuvastatin and Atorvastatin Are Ligands of the Human Constitutive Androstane Receptor/Retinoid X Receptor α Complex
      Tadeja Režen, Mateja Hafner, Sandhya Kortagere, Sean Ekins, Vesna Hodnik and Damjana Rozman
      Drug Metabolism and Disposition August 2017, 45 (8) 974-976; DOI: https://doi.org/10.1124/dmd.117.075523

  4. Holenarsipur, Vinay K.

    1. Comparative Evaluation of Plasma Bile Acids, Dehydroepiandrosterone Sulfate, Hexadecanedioate, and Tetradecanedioate with Coproporphyrins I and III as Markers of OATP Inhibition in Healthy Subjects
      Hong Shen, Weiqi Chen, Dieter M. Drexler, Sandhya Mandlekar, Vinay K. Holenarsipur, Eric E. Shields, Robert Langish, Kurex Sidik, Jinping Gan, W. Griffith Humphreys, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition August 2017, 45 (8) 908-919; DOI: https://doi.org/10.1124/dmd.117.075531

  5. Humphreys, W. Griffith

    1. Comparative Evaluation of Plasma Bile Acids, Dehydroepiandrosterone Sulfate, Hexadecanedioate, and Tetradecanedioate with Coproporphyrins I and III as Markers of OATP Inhibition in Healthy Subjects
      Hong Shen, Weiqi Chen, Dieter M. Drexler, Sandhya Mandlekar, Vinay K. Holenarsipur, Eric E. Shields, Robert Langish, Kurex Sidik, Jinping Gan, W. Griffith Humphreys, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition August 2017, 45 (8) 908-919; DOI: https://doi.org/10.1124/dmd.117.075531

I

  1. Imperial, Marjorie Z.

    1. Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model I: Insights into Factors that Determine Fetal Drug Exposure through Simulations and Sensitivity Analyses
      Zufei Zhang, Marjorie Z. Imperial, Gabriela I. Patilea-Vrana, Janak Wedagedera, Lu Gaohua and Jashvant D. Unadkat
      Drug Metabolism and Disposition August 2017, 45 (8) 920-938; DOI: https://doi.org/10.1124/dmd.117.075192

  2. Inoue, Takashi

    1. Molecular Cloning and Characterization of Marmoset Aldehyde Oxidase
      Molecular Cloning and Characterization of Marmoset Aldehyde Oxidase
      Shotaro Uehara, Yasuhiro Uno, Eriko Okamoto, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition August 2017, 45 (8) 883-886; DOI: https://doi.org/10.1124/dmd.117.076042
    2. Regio- and Stereo-Selective Oxidation of a Cardiovascular Drug, Metoprolol, Mediated by Cytochrome P450 2D and 3A Enzymes in Marmoset Livers
      Regio- and Stereo-Selective Oxidation of a Cardiovascular Drug, Metoprolol, Mediated by Cytochrome P450 2D and 3A Enzymes in Marmoset Livers
      Shotaro Uehara, Sakura Ishii, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition August 2017, 45 (8) 896-899; DOI: https://doi.org/10.1124/dmd.117.075630

  3. Ishii, Sakura

    1. Regio- and Stereo-Selective Oxidation of a Cardiovascular Drug, Metoprolol, Mediated by Cytochrome P450 2D and 3A Enzymes in Marmoset Livers
      Regio- and Stereo-Selective Oxidation of a Cardiovascular Drug, Metoprolol, Mediated by Cytochrome P450 2D and 3A Enzymes in Marmoset Livers
      Shotaro Uehara, Sakura Ishii, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition August 2017, 45 (8) 896-899; DOI: https://doi.org/10.1124/dmd.117.075630

  4. Israni, Ajay K.

    1. CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism
      Casey R. Dorr, Rory P. Remmel, Amutha Muthusamy, James Fisher, Branden S. Moriarity, Kazuto Yasuda, Baolin Wu, Weihua Guan, Erin G. Schuetz, William S. Oetting, Pamala A. Jacobson and Ajay K. Israni
      Drug Metabolism and Disposition August 2017, 45 (8) 957-965; DOI: https://doi.org/10.1124/dmd.117.076307

J

  1. Jacobson, Pamala A.

    1. CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism
      Casey R. Dorr, Rory P. Remmel, Amutha Muthusamy, James Fisher, Branden S. Moriarity, Kazuto Yasuda, Baolin Wu, Weihua Guan, Erin G. Schuetz, William S. Oetting, Pamala A. Jacobson and Ajay K. Israni
      Drug Metabolism and Disposition August 2017, 45 (8) 957-965; DOI: https://doi.org/10.1124/dmd.117.076307

  2. James, Alexander David

    1. Open Access
      Comparison of 19F NMR and 14C Measurements for the Assessment of ADME of BYL719 (Alpelisib) in Humans
      Alexander David James, Cyrille Marvalin, Alexandre Luneau, Axel Meissner and Gian Camenisch
      Drug Metabolism and Disposition August 2017, 45 (8) 900-907; DOI: https://doi.org/10.1124/dmd.117.075424

  3. Johansson, Anders

    1. Oxetane Substrates of Human Microsomal Epoxide Hydrolase
      Oxetane Substrates of Human Microsomal Epoxide Hydrolase
      Francesca Toselli, Marlene Fredenwall, Peder Svensson, Xue-Qing Li, Anders Johansson, Lars Weidolf and Martin A. Hayes
      Drug Metabolism and Disposition August 2017, 45 (8) 966-973; DOI: https://doi.org/10.1124/dmd.117.076489

K

  1. Kortagere, Sandhya

    1. Rosuvastatin and Atorvastatin Are Ligands of the Human Constitutive Androstane Receptor/Retinoid X Receptor α Complex
      Tadeja Režen, Mateja Hafner, Sandhya Kortagere, Sean Ekins, Vesna Hodnik and Damjana Rozman
      Drug Metabolism and Disposition August 2017, 45 (8) 974-976; DOI: https://doi.org/10.1124/dmd.117.075523

  2. Kücükgöze, Gökhan

    1. Direct Comparison of the Enzymatic Characteristics and Superoxide Production of the Four Aldehyde Oxidase Enzymes Present in Mouse
      Gökhan Kücükgöze, Mineko Terao, Enrico Garattini and Silke Leimkühler
      Drug Metabolism and Disposition August 2017, 45 (8) 947-955; DOI: https://doi.org/10.1124/dmd.117.075937

L

  1. Lai, Yurong

    1. Comparative Evaluation of Plasma Bile Acids, Dehydroepiandrosterone Sulfate, Hexadecanedioate, and Tetradecanedioate with Coproporphyrins I and III as Markers of OATP Inhibition in Healthy Subjects
      Hong Shen, Weiqi Chen, Dieter M. Drexler, Sandhya Mandlekar, Vinay K. Holenarsipur, Eric E. Shields, Robert Langish, Kurex Sidik, Jinping Gan, W. Griffith Humphreys, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition August 2017, 45 (8) 908-919; DOI: https://doi.org/10.1124/dmd.117.075531

  2. Langish, Robert

    1. Comparative Evaluation of Plasma Bile Acids, Dehydroepiandrosterone Sulfate, Hexadecanedioate, and Tetradecanedioate with Coproporphyrins I and III as Markers of OATP Inhibition in Healthy Subjects
      Hong Shen, Weiqi Chen, Dieter M. Drexler, Sandhya Mandlekar, Vinay K. Holenarsipur, Eric E. Shields, Robert Langish, Kurex Sidik, Jinping Gan, W. Griffith Humphreys, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition August 2017, 45 (8) 908-919; DOI: https://doi.org/10.1124/dmd.117.075531

  3. Leimkühler, Silke

    1. Direct Comparison of the Enzymatic Characteristics and Superoxide Production of the Four Aldehyde Oxidase Enzymes Present in Mouse
      Gökhan Kücükgöze, Mineko Terao, Enrico Garattini and Silke Leimkühler
      Drug Metabolism and Disposition August 2017, 45 (8) 947-955; DOI: https://doi.org/10.1124/dmd.117.075937

  4. Li, Lei

    1. Role of CYP2B in Phenobarbital-Induced Hepatocyte Proliferation in Mice
      Lei Li, Xiaochen Bao, Qing-Yu Zhang, Masahiko Negishi and Xinxin Ding
      Drug Metabolism and Disposition August 2017, 45 (8) 977-981; DOI: https://doi.org/10.1124/dmd.117.076406

  5. Li, Xue-Qing

    1. Oxetane Substrates of Human Microsomal Epoxide Hydrolase
      Oxetane Substrates of Human Microsomal Epoxide Hydrolase
      Francesca Toselli, Marlene Fredenwall, Peder Svensson, Xue-Qing Li, Anders Johansson, Lars Weidolf and Martin A. Hayes
      Drug Metabolism and Disposition August 2017, 45 (8) 966-973; DOI: https://doi.org/10.1124/dmd.117.076489

  6. Liu, Chenchang

    1. PKC/Nedd4-2 Signaling Pathway Regulates the Cell Surface Expression of Drug Transporter hOAT1
      Da Xu, Jinghui Zhang, Qiang Zhang, Yunzhou Fan, Chenchang Liu and Guofeng You
      Drug Metabolism and Disposition August 2017, 45 (8) 887-895; DOI: https://doi.org/10.1124/dmd.117.075861

  7. Luneau, Alexandre

    1. Open Access
      Comparison of 19F NMR and 14C Measurements for the Assessment of ADME of BYL719 (Alpelisib) in Humans
      Alexander David James, Cyrille Marvalin, Alexandre Luneau, Axel Meissner and Gian Camenisch
      Drug Metabolism and Disposition August 2017, 45 (8) 900-907; DOI: https://doi.org/10.1124/dmd.117.075424

M

  1. Mandlekar, Sandhya

    1. Comparative Evaluation of Plasma Bile Acids, Dehydroepiandrosterone Sulfate, Hexadecanedioate, and Tetradecanedioate with Coproporphyrins I and III as Markers of OATP Inhibition in Healthy Subjects
      Hong Shen, Weiqi Chen, Dieter M. Drexler, Sandhya Mandlekar, Vinay K. Holenarsipur, Eric E. Shields, Robert Langish, Kurex Sidik, Jinping Gan, W. Griffith Humphreys, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition August 2017, 45 (8) 908-919; DOI: https://doi.org/10.1124/dmd.117.075531

  2. Marathe, Punit

    1. Comparative Evaluation of Plasma Bile Acids, Dehydroepiandrosterone Sulfate, Hexadecanedioate, and Tetradecanedioate with Coproporphyrins I and III as Markers of OATP Inhibition in Healthy Subjects
      Hong Shen, Weiqi Chen, Dieter M. Drexler, Sandhya Mandlekar, Vinay K. Holenarsipur, Eric E. Shields, Robert Langish, Kurex Sidik, Jinping Gan, W. Griffith Humphreys, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition August 2017, 45 (8) 908-919; DOI: https://doi.org/10.1124/dmd.117.075531

  3. Marvalin, Cyrille

    1. Open Access
      Comparison of 19F NMR and 14C Measurements for the Assessment of ADME of BYL719 (Alpelisib) in Humans
      Alexander David James, Cyrille Marvalin, Alexandre Luneau, Axel Meissner and Gian Camenisch
      Drug Metabolism and Disposition August 2017, 45 (8) 900-907; DOI: https://doi.org/10.1124/dmd.117.075424

  4. Meissner, Axel

    1. Open Access
      Comparison of 19F NMR and 14C Measurements for the Assessment of ADME of BYL719 (Alpelisib) in Humans
      Alexander David James, Cyrille Marvalin, Alexandre Luneau, Axel Meissner and Gian Camenisch
      Drug Metabolism and Disposition August 2017, 45 (8) 900-907; DOI: https://doi.org/10.1124/dmd.117.075424

  5. Moriarity, Branden S.

    1. CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism
      Casey R. Dorr, Rory P. Remmel, Amutha Muthusamy, James Fisher, Branden S. Moriarity, Kazuto Yasuda, Baolin Wu, Weihua Guan, Erin G. Schuetz, William S. Oetting, Pamala A. Jacobson and Ajay K. Israni
      Drug Metabolism and Disposition August 2017, 45 (8) 957-965; DOI: https://doi.org/10.1124/dmd.117.076307

  6. Muthusamy, Amutha

    1. CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism
      Casey R. Dorr, Rory P. Remmel, Amutha Muthusamy, James Fisher, Branden S. Moriarity, Kazuto Yasuda, Baolin Wu, Weihua Guan, Erin G. Schuetz, William S. Oetting, Pamala A. Jacobson and Ajay K. Israni
      Drug Metabolism and Disposition August 2017, 45 (8) 957-965; DOI: https://doi.org/10.1124/dmd.117.076307

N

  1. Negishi, Masahiko

    1. Role of CYP2B in Phenobarbital-Induced Hepatocyte Proliferation in Mice
      Lei Li, Xiaochen Bao, Qing-Yu Zhang, Masahiko Negishi and Xinxin Ding
      Drug Metabolism and Disposition August 2017, 45 (8) 977-981; DOI: https://doi.org/10.1124/dmd.117.076406

O

  1. Oetting, William S.

    1. CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism
      Casey R. Dorr, Rory P. Remmel, Amutha Muthusamy, James Fisher, Branden S. Moriarity, Kazuto Yasuda, Baolin Wu, Weihua Guan, Erin G. Schuetz, William S. Oetting, Pamala A. Jacobson and Ajay K. Israni
      Drug Metabolism and Disposition August 2017, 45 (8) 957-965; DOI: https://doi.org/10.1124/dmd.117.076307

  2. Okamoto, Eriko

    1. Molecular Cloning and Characterization of Marmoset Aldehyde Oxidase
      Molecular Cloning and Characterization of Marmoset Aldehyde Oxidase
      Shotaro Uehara, Yasuhiro Uno, Eriko Okamoto, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition August 2017, 45 (8) 883-886; DOI: https://doi.org/10.1124/dmd.117.076042

P

  1. Patilea-Vrana, Gabriela I.

    1. Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model I: Insights into Factors that Determine Fetal Drug Exposure through Simulations and Sensitivity Analyses
      Zufei Zhang, Marjorie Z. Imperial, Gabriela I. Patilea-Vrana, Janak Wedagedera, Lu Gaohua and Jashvant D. Unadkat
      Drug Metabolism and Disposition August 2017, 45 (8) 920-938; DOI: https://doi.org/10.1124/dmd.117.075192

R

  1. Remmel, Rory P.

    1. CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism
      Casey R. Dorr, Rory P. Remmel, Amutha Muthusamy, James Fisher, Branden S. Moriarity, Kazuto Yasuda, Baolin Wu, Weihua Guan, Erin G. Schuetz, William S. Oetting, Pamala A. Jacobson and Ajay K. Israni
      Drug Metabolism and Disposition August 2017, 45 (8) 957-965; DOI: https://doi.org/10.1124/dmd.117.076307

  2. Režen, Tadeja

    1. Rosuvastatin and Atorvastatin Are Ligands of the Human Constitutive Androstane Receptor/Retinoid X Receptor α Complex
      Tadeja Režen, Mateja Hafner, Sandhya Kortagere, Sean Ekins, Vesna Hodnik and Damjana Rozman
      Drug Metabolism and Disposition August 2017, 45 (8) 974-976; DOI: https://doi.org/10.1124/dmd.117.075523

  3. Rozman, Damjana

    1. Rosuvastatin and Atorvastatin Are Ligands of the Human Constitutive Androstane Receptor/Retinoid X Receptor α Complex
      Tadeja Režen, Mateja Hafner, Sandhya Kortagere, Sean Ekins, Vesna Hodnik and Damjana Rozman
      Drug Metabolism and Disposition August 2017, 45 (8) 974-976; DOI: https://doi.org/10.1124/dmd.117.075523

S

  1. Sasaki, Erika

    1. Molecular Cloning and Characterization of Marmoset Aldehyde Oxidase
      Molecular Cloning and Characterization of Marmoset Aldehyde Oxidase
      Shotaro Uehara, Yasuhiro Uno, Eriko Okamoto, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition August 2017, 45 (8) 883-886; DOI: https://doi.org/10.1124/dmd.117.076042
    2. Regio- and Stereo-Selective Oxidation of a Cardiovascular Drug, Metoprolol, Mediated by Cytochrome P450 2D and 3A Enzymes in Marmoset Livers
      Regio- and Stereo-Selective Oxidation of a Cardiovascular Drug, Metoprolol, Mediated by Cytochrome P450 2D and 3A Enzymes in Marmoset Livers
      Shotaro Uehara, Sakura Ishii, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition August 2017, 45 (8) 896-899; DOI: https://doi.org/10.1124/dmd.117.075630

  2. Schuetz, Erin G.

    1. CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism
      Casey R. Dorr, Rory P. Remmel, Amutha Muthusamy, James Fisher, Branden S. Moriarity, Kazuto Yasuda, Baolin Wu, Weihua Guan, Erin G. Schuetz, William S. Oetting, Pamala A. Jacobson and Ajay K. Israni
      Drug Metabolism and Disposition August 2017, 45 (8) 957-965; DOI: https://doi.org/10.1124/dmd.117.076307

  3. Shen, Hong

    1. Comparative Evaluation of Plasma Bile Acids, Dehydroepiandrosterone Sulfate, Hexadecanedioate, and Tetradecanedioate with Coproporphyrins I and III as Markers of OATP Inhibition in Healthy Subjects
      Hong Shen, Weiqi Chen, Dieter M. Drexler, Sandhya Mandlekar, Vinay K. Holenarsipur, Eric E. Shields, Robert Langish, Kurex Sidik, Jinping Gan, W. Griffith Humphreys, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition August 2017, 45 (8) 908-919; DOI: https://doi.org/10.1124/dmd.117.075531

  4. Shields, Eric E.

    1. Comparative Evaluation of Plasma Bile Acids, Dehydroepiandrosterone Sulfate, Hexadecanedioate, and Tetradecanedioate with Coproporphyrins I and III as Markers of OATP Inhibition in Healthy Subjects
      Hong Shen, Weiqi Chen, Dieter M. Drexler, Sandhya Mandlekar, Vinay K. Holenarsipur, Eric E. Shields, Robert Langish, Kurex Sidik, Jinping Gan, W. Griffith Humphreys, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition August 2017, 45 (8) 908-919; DOI: https://doi.org/10.1124/dmd.117.075531

  5. Sidik, Kurex

    1. Comparative Evaluation of Plasma Bile Acids, Dehydroepiandrosterone Sulfate, Hexadecanedioate, and Tetradecanedioate with Coproporphyrins I and III as Markers of OATP Inhibition in Healthy Subjects
      Hong Shen, Weiqi Chen, Dieter M. Drexler, Sandhya Mandlekar, Vinay K. Holenarsipur, Eric E. Shields, Robert Langish, Kurex Sidik, Jinping Gan, W. Griffith Humphreys, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition August 2017, 45 (8) 908-919; DOI: https://doi.org/10.1124/dmd.117.075531

  6. Svensson, Peder

    1. Oxetane Substrates of Human Microsomal Epoxide Hydrolase
      Oxetane Substrates of Human Microsomal Epoxide Hydrolase
      Francesca Toselli, Marlene Fredenwall, Peder Svensson, Xue-Qing Li, Anders Johansson, Lars Weidolf and Martin A. Hayes
      Drug Metabolism and Disposition August 2017, 45 (8) 966-973; DOI: https://doi.org/10.1124/dmd.117.076489

T

  1. Terao, Mineko

    1. Direct Comparison of the Enzymatic Characteristics and Superoxide Production of the Four Aldehyde Oxidase Enzymes Present in Mouse
      Gökhan Kücükgöze, Mineko Terao, Enrico Garattini and Silke Leimkühler
      Drug Metabolism and Disposition August 2017, 45 (8) 947-955; DOI: https://doi.org/10.1124/dmd.117.075937

  2. Toselli, Francesca

    1. Oxetane Substrates of Human Microsomal Epoxide Hydrolase
      Oxetane Substrates of Human Microsomal Epoxide Hydrolase
      Francesca Toselli, Marlene Fredenwall, Peder Svensson, Xue-Qing Li, Anders Johansson, Lars Weidolf and Martin A. Hayes
      Drug Metabolism and Disposition August 2017, 45 (8) 966-973; DOI: https://doi.org/10.1124/dmd.117.076489

U

  1. Uehara, Shotaro

    1. Molecular Cloning and Characterization of Marmoset Aldehyde Oxidase
      Molecular Cloning and Characterization of Marmoset Aldehyde Oxidase
      Shotaro Uehara, Yasuhiro Uno, Eriko Okamoto, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition August 2017, 45 (8) 883-886; DOI: https://doi.org/10.1124/dmd.117.076042
    2. Regio- and Stereo-Selective Oxidation of a Cardiovascular Drug, Metoprolol, Mediated by Cytochrome P450 2D and 3A Enzymes in Marmoset Livers
      Regio- and Stereo-Selective Oxidation of a Cardiovascular Drug, Metoprolol, Mediated by Cytochrome P450 2D and 3A Enzymes in Marmoset Livers
      Shotaro Uehara, Sakura Ishii, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition August 2017, 45 (8) 896-899; DOI: https://doi.org/10.1124/dmd.117.075630

  2. Unadkat, Jashvant D.

    1. Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model I: Insights into Factors that Determine Fetal Drug Exposure through Simulations and Sensitivity Analyses
      Zufei Zhang, Marjorie Z. Imperial, Gabriela I. Patilea-Vrana, Janak Wedagedera, Lu Gaohua and Jashvant D. Unadkat
      Drug Metabolism and Disposition August 2017, 45 (8) 920-938; DOI: https://doi.org/10.1124/dmd.117.075192
    2. Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model II: Verification of the Model for Passive Placental Permeability Drugs
      Zufei Zhang and Jashvant D. Unadkat
      Drug Metabolism and Disposition August 2017, 45 (8) 939-946; DOI: https://doi.org/10.1124/dmd.116.073957

  3. Uno, Yasuhiro

    1. Molecular Cloning and Characterization of Marmoset Aldehyde Oxidase
      Molecular Cloning and Characterization of Marmoset Aldehyde Oxidase
      Shotaro Uehara, Yasuhiro Uno, Eriko Okamoto, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition August 2017, 45 (8) 883-886; DOI: https://doi.org/10.1124/dmd.117.076042
    2. Regio- and Stereo-Selective Oxidation of a Cardiovascular Drug, Metoprolol, Mediated by Cytochrome P450 2D and 3A Enzymes in Marmoset Livers
      Regio- and Stereo-Selective Oxidation of a Cardiovascular Drug, Metoprolol, Mediated by Cytochrome P450 2D and 3A Enzymes in Marmoset Livers
      Shotaro Uehara, Sakura Ishii, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition August 2017, 45 (8) 896-899; DOI: https://doi.org/10.1124/dmd.117.075630

W

  1. Wedagedera, Janak

    1. Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model I: Insights into Factors that Determine Fetal Drug Exposure through Simulations and Sensitivity Analyses
      Zufei Zhang, Marjorie Z. Imperial, Gabriela I. Patilea-Vrana, Janak Wedagedera, Lu Gaohua and Jashvant D. Unadkat
      Drug Metabolism and Disposition August 2017, 45 (8) 920-938; DOI: https://doi.org/10.1124/dmd.117.075192

  2. Weidolf, Lars

    1. Oxetane Substrates of Human Microsomal Epoxide Hydrolase
      Oxetane Substrates of Human Microsomal Epoxide Hydrolase
      Francesca Toselli, Marlene Fredenwall, Peder Svensson, Xue-Qing Li, Anders Johansson, Lars Weidolf and Martin A. Hayes
      Drug Metabolism and Disposition August 2017, 45 (8) 966-973; DOI: https://doi.org/10.1124/dmd.117.076489

  3. Wu, Baolin

    1. CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism
      Casey R. Dorr, Rory P. Remmel, Amutha Muthusamy, James Fisher, Branden S. Moriarity, Kazuto Yasuda, Baolin Wu, Weihua Guan, Erin G. Schuetz, William S. Oetting, Pamala A. Jacobson and Ajay K. Israni
      Drug Metabolism and Disposition August 2017, 45 (8) 957-965; DOI: https://doi.org/10.1124/dmd.117.076307

X

  1. Xu, Da

    1. PKC/Nedd4-2 Signaling Pathway Regulates the Cell Surface Expression of Drug Transporter hOAT1
      Da Xu, Jinghui Zhang, Qiang Zhang, Yunzhou Fan, Chenchang Liu and Guofeng You
      Drug Metabolism and Disposition August 2017, 45 (8) 887-895; DOI: https://doi.org/10.1124/dmd.117.075861

Y

  1. Yamazaki, Hiroshi

    1. Molecular Cloning and Characterization of Marmoset Aldehyde Oxidase
      Molecular Cloning and Characterization of Marmoset Aldehyde Oxidase
      Shotaro Uehara, Yasuhiro Uno, Eriko Okamoto, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition August 2017, 45 (8) 883-886; DOI: https://doi.org/10.1124/dmd.117.076042
    2. Regio- and Stereo-Selective Oxidation of a Cardiovascular Drug, Metoprolol, Mediated by Cytochrome P450 2D and 3A Enzymes in Marmoset Livers
      Regio- and Stereo-Selective Oxidation of a Cardiovascular Drug, Metoprolol, Mediated by Cytochrome P450 2D and 3A Enzymes in Marmoset Livers
      Shotaro Uehara, Sakura Ishii, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition August 2017, 45 (8) 896-899; DOI: https://doi.org/10.1124/dmd.117.075630

  2. Yasuda, Kazuto

    1. CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism
      Casey R. Dorr, Rory P. Remmel, Amutha Muthusamy, James Fisher, Branden S. Moriarity, Kazuto Yasuda, Baolin Wu, Weihua Guan, Erin G. Schuetz, William S. Oetting, Pamala A. Jacobson and Ajay K. Israni
      Drug Metabolism and Disposition August 2017, 45 (8) 957-965; DOI: https://doi.org/10.1124/dmd.117.076307

  3. You, Guofeng

    1. PKC/Nedd4-2 Signaling Pathway Regulates the Cell Surface Expression of Drug Transporter hOAT1
      Da Xu, Jinghui Zhang, Qiang Zhang, Yunzhou Fan, Chenchang Liu and Guofeng You
      Drug Metabolism and Disposition August 2017, 45 (8) 887-895; DOI: https://doi.org/10.1124/dmd.117.075861

Z

  1. Zhang, Jinghui

    1. PKC/Nedd4-2 Signaling Pathway Regulates the Cell Surface Expression of Drug Transporter hOAT1
      Da Xu, Jinghui Zhang, Qiang Zhang, Yunzhou Fan, Chenchang Liu and Guofeng You
      Drug Metabolism and Disposition August 2017, 45 (8) 887-895; DOI: https://doi.org/10.1124/dmd.117.075861

  2. Zhang, Qiang

    1. PKC/Nedd4-2 Signaling Pathway Regulates the Cell Surface Expression of Drug Transporter hOAT1
      Da Xu, Jinghui Zhang, Qiang Zhang, Yunzhou Fan, Chenchang Liu and Guofeng You
      Drug Metabolism and Disposition August 2017, 45 (8) 887-895; DOI: https://doi.org/10.1124/dmd.117.075861

  3. Zhang, Qing-Yu

    1. Role of CYP2B in Phenobarbital-Induced Hepatocyte Proliferation in Mice
      Lei Li, Xiaochen Bao, Qing-Yu Zhang, Masahiko Negishi and Xinxin Ding
      Drug Metabolism and Disposition August 2017, 45 (8) 977-981; DOI: https://doi.org/10.1124/dmd.117.076406

  4. Zhang, Zufei

    1. Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model I: Insights into Factors that Determine Fetal Drug Exposure through Simulations and Sensitivity Analyses
      Zufei Zhang, Marjorie Z. Imperial, Gabriela I. Patilea-Vrana, Janak Wedagedera, Lu Gaohua and Jashvant D. Unadkat
      Drug Metabolism and Disposition August 2017, 45 (8) 920-938; DOI: https://doi.org/10.1124/dmd.117.075192
    2. Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model II: Verification of the Model for Passive Placental Permeability Drugs
      Zufei Zhang and Jashvant D. Unadkat
      Drug Metabolism and Disposition August 2017, 45 (8) 939-946; DOI: https://doi.org/10.1124/dmd.116.073957
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