Table of Contents

Articles

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  Bioengineered NRF2-siRNA Is Effective to Interfere with NRF2 Pathways and Improve Chemosensitivity of Human Cancer Cells

  Peng-Cheng Li, Mei-Juan Tu, Pui Yan Ho, Joseph L. Jilek, Zhijian Duan, Qian-Yu Zhang, Ai-Xi Yu and Ai-Ming Yu

  Drug Metabolism and Disposition January 2018, 46 (1) 2-10; DOI: https://doi.org/10.1124/dmd.117.078741
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  Organic Anion–Transporting Polypeptide (OATP)–Mediated Drug-Drug Interaction Study between Rosuvastatin and Cyclosporine A in Chimeric Mice with Humanized Liver

  Masashi Uchida, Yoriko Tajima, Masakazu Kakuni, Yutaka Kageyama, Taro Okada, Eri Sakurada, Chise Tateno and Ryoji Hayashi

  Drug Metabolism and Disposition January 2018, 46 (1) 11-19; DOI: https://doi.org/10.1124/dmd.117.075994
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  Effect of Flavin-Containing Monooxygenase Genotype, Mouse Strain, and Gender on Trimethylamine N-oxide Production, Plasma Cholesterol Concentration, and an Index of Atherosclerosis

  Sunil Veeravalli, Kersti Karu, Flora Scott, Diede Fennema, Ian R. Phillips and Elizabeth A. Shephard

  Drug Metabolism and Disposition January 2018, 46 (1) 20-25; DOI: https://doi.org/10.1124/dmd.117.077636
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  Evaluation of Clinical Drug Interaction Potential of Clofazimine Using Static and Dynamic Modeling Approaches

  Ramachandra Sangana, Helen Gu, Dung Yu Chun and Heidi J. Einolf

  Drug Metabolism and Disposition January 2018, 46 (1) 26-32; DOI: https://doi.org/10.1124/dmd.117.077834
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  Organic Cation Transporter 1 Is Responsible for Hepatocellular Uptake of the Tyrosine Kinase Inhibitor Pazopanib

  Waleed Elsayed Ahmed Ellawatty, Yusuke Masuo, Ken-ichi Fujita, Erina Yamazaki, Hiroo Ishida, Hiroshi Arakawa, Noritaka Nakamichi, Ramadan Abdelwahed, Yasutsuna Sasaki and Yukio Kato

  Drug Metabolism and Disposition January 2018, 46 (1) 33-40; DOI: https://doi.org/10.1124/dmd.117.076554
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  Tripartite Motif Containing 24 Acts as a Novel Coactivator of the Constitutive Active/Androstane Receptor

  Yuichiro Kanno, Yuki Kure, Saori Kobayashi, Mariko Mizuno, Yumi Tsuchiya, Naoya Yamashita, Kiyomitsu Nemoto and Yoshio Inouye

  Drug Metabolism and Disposition January 2018, 46 (1) 46-52; DOI: https://doi.org/10.1124/dmd.117.077693
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  Low Cerebral Exposure Cannot Hinder the Neuroprotective Effects of Panax Notoginsenosides

  Haofeng Li, Jingcheng Xiao, Xinuo Li, Huimin Chen, Dian Kang, Yuhao Shao, Boyu Shen, Zhangpei Zhu, Xiaoxi Yin, Lin Xie, Guangji Wang and Yan Liang

  Drug Metabolism and Disposition January 2018, 46 (1) 53-65; DOI: https://doi.org/10.1124/dmd.117.078436
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  Successful Prediction of In Vivo Hepatobiliary Clearances and Hepatic Concentrations of Rosuvastatin Using Sandwich-Cultured Rat Hepatocytes, Transporter-Expressing Cell Lines, and Quantitative Proteomics

  Kazuya Ishida, Mohammed Ullah, Beáta Tóth, Viktoria Juhasz and Jashvant D. Unadkat

  Drug Metabolism and Disposition January 2018, 46 (1) 66-74; DOI: https://doi.org/10.1124/dmd.117.076539
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  Highlighting Vitamin D Receptor–Targeted Activities of 1α,25-Dihydroxyvitamin D₃ in Mice via Physiologically Based Pharmacokinetic-Pharmacodynamic Modeling

  Qi Joy Yang, Paola Bukuroshi, Holly P. Quach, Edwin C. Y. Chow and K. Sandy Pang

  Drug Metabolism and Disposition January 2018, 46 (1) 75-87; DOI: https://doi.org/10.1124/dmd.117.077271