Table of Contents

Articles

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  Associations between Cytokine Levels and CYP3A4 Phenotype in Patients with Rheumatoid Arthritis

  Birgit M. Wollmann, Silje Watterdal Syversen, Maria Vistnes, Elisabeth Lie, Lise L. Mehus and Espen Molden

  Drug Metabolism and Disposition October 2018, 46 (10) 1384-1389; DOI: https://doi.org/10.1124/dmd.118.082065
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  Metabolism of Anethole Dithiolethione by Rat and Human Liver Microsomes: Formation of Various Products Deriving from Its O-Demethylation and S-Oxidation. Involvement of Cytochromes P450 and Flavin Monooxygenases in These Pathways

  Martin Dulac, Amor Sassi, Citra Nagarathinan, Marie-Odile Christen, Patrick M. Dansette, Daniel Mansuy and Jean-Luc Boucher

  Drug Metabolism and Disposition October 2018, 46 (10) 1390-1395; DOI: https://doi.org/10.1124/dmd.118.082545
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  The Involvement of the Mitochondrial Amidoxime Reducing Component (mARC) in the Reductive Metabolism of Hydroxamic Acids

  Carsten Ginsel, Birte Plitzko, Danilo Froriep, Diana A. Stolfa, Manfred Jung, Christian Kubitza, Axel J. Scheidig, Antje Havemeyer and Bernd Clement

  Drug Metabolism and Disposition October 2018, 46 (10) 1396-1402; DOI: https://doi.org/10.1124/dmd.118.082453
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  The Clock Protein Bmal1 Regulates Circadian Expression and Activity of Sulfotransferase 1a1 in Mice

  Lianxia Guo, Fangjun Yu, Tianpeng Zhang and Baojian Wu

  Drug Metabolism and Disposition October 2018, 46 (10) 1403-1410; DOI: https://doi.org/10.1124/dmd.118.082503
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  Cyclic AMP Signaling Promotes the Differentiation of Human Induced Pluripotent Stem Cells into Intestinal Epithelial Cells

  Tomoki Kabeya, Shimeng Qiu, Momona Hibino, Mizuka Nagasaki, Nao Kodama, Takahiro Iwao and Tamihide Matsunaga

  Drug Metabolism and Disposition October 2018, 46 (10) 1411-1419; DOI: https://doi.org/10.1124/dmd.118.082123
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  Physiologically Based Pharmacokinetic Model of Itraconazole and Two of Its Metabolites to Improve the Predictions and the Mechanistic Understanding of CYP3A4 Drug-Drug Interactions

  Luna Prieto Garcia, David Janzén, Kajsa P. Kanebratt, Hans Ericsson, Hans Lennernäs and Anna Lundahl

  Drug Metabolism and Disposition October 2018, 46 (10) 1420-1433; DOI: https://doi.org/10.1124/dmd.118.081364
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  Identification and Characterization of a Selective Human Carbonyl Reductase 1 Substrate

  Diane Ramsden, Dustin Smith, Raquel Arenas, Kosea Frederick and Matthew A. Cerny

  Drug Metabolism and Disposition October 2018, 46 (10) 1434-1440; DOI: https://doi.org/10.1124/dmd.118.082487
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  The Importance of Incorporating OCT2 Plasma Membrane Expression and Membrane Potential in IVIVE of Metformin Renal Secretory Clearance

  Vineet Kumar, Jia Yin, Sarah Billington, Bhagwat Prasad, Colin D. A. Brown, Joanne Wang and Jashvant D. Unadkat

  Drug Metabolism and Disposition October 2018, 46 (10) 1441-1445; DOI: https://doi.org/10.1124/dmd.118.082313
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  Oligomerization and Catalytic Parameters of Human UDP-Glucuronosyltransferase 1A10: Expression and Characterization of the Recombinant Protein

  Kyungbo Kim, Fang Zheng and Chang-Guo Zhan

  Drug Metabolism and Disposition October 2018, 46 (10) 1446-1452; DOI: https://doi.org/10.1124/dmd.118.082495
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  Biotransformation of Ilaprazole in Human Liver Microsomes and Human: Role of CYP3A4 in Ilaprazole Clearance and Drug-Drug Interaction

  Jie Pu, Fen Wang, Wei Tang and Mingshe Zhu

  Drug Metabolism and Disposition October 2018, 46 (10) 1453-1461; DOI: https://doi.org/10.1124/dmd.118.081570