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Research ArticleArticle

The Importance of Incorporating OCT2 Plasma Membrane Expression and Membrane Potential in IVIVE of Metformin Renal Secretory Clearance

Vineet Kumar, Jia Yin, Sarah Billington, Bhagwat Prasad, Colin D. A. Brown, Joanne Wang and Jashvant D. Unadkat
Drug Metabolism and Disposition October 2018, 46 (10) 1441-1445; DOI: https://doi.org/10.1124/dmd.118.082313

Article Information

vol. 46 no. 10 1441-1445
DOI 
https://doi.org/10.1124/dmd.118.082313
PubMed 
30093416
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received May 12, 2018
  • Accepted August 3, 2018
  • Published online September 7, 2018.

Article Versions

Copyright & Usage 
Copyright © 2018 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Vineet Kumar,
  2. Jia Yin,
  3. Sarah Billington,
  4. Bhagwat Prasad,
  5. Colin D. A. Brown,
  6. Joanne Wang, and
  7. Jashvant D. Unadkat
  1. Department of Pharmaceutics, University of Washington, Seattle, Washington (V.K., J.Y., B.P., J.W., J.D.U.) and Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, United Kingdom (S.B., C.D.A.B.)
  1. Address correspondence to:
    Jashvant D. Unadkat, Department of Pharmaceutics, University of Washington, Seattle, P.O. Box 357610, WA 98195. E-mail: jash{at}uw.edu
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IVIVE of Renal Secretory Clearance of Metformin

Vineet Kumar, Jia Yin, Sarah Billington, Bhagwat Prasad, Colin D. A. Brown, Joanne Wang and Jashvant D. Unadkat
Drug Metabolism and Disposition October 1, 2018, 46 (10) 1441-1445; DOI: https://doi.org/10.1124/dmd.118.082313
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