Research ArticleArticle
The Importance of Incorporating OCT2 Plasma Membrane Expression and Membrane Potential in IVIVE of Metformin Renal Secretory Clearance
Vineet Kumar, Jia Yin, Sarah Billington, Bhagwat Prasad, Colin D. A. Brown, Joanne Wang and Jashvant D. Unadkat
Drug Metabolism and Disposition October 2018, 46 (10) 1441-1445; DOI: https://doi.org/10.1124/dmd.118.082313
Vineet Kumar
Department of Pharmaceutics, University of Washington, Seattle, Washington (V.K., J.Y., B.P., J.W., J.D.U.) and Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, United Kingdom (S.B., C.D.A.B.)
Jia Yin
Department of Pharmaceutics, University of Washington, Seattle, Washington (V.K., J.Y., B.P., J.W., J.D.U.) and Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, United Kingdom (S.B., C.D.A.B.)
Sarah Billington
Department of Pharmaceutics, University of Washington, Seattle, Washington (V.K., J.Y., B.P., J.W., J.D.U.) and Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, United Kingdom (S.B., C.D.A.B.)
Bhagwat Prasad
Department of Pharmaceutics, University of Washington, Seattle, Washington (V.K., J.Y., B.P., J.W., J.D.U.) and Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, United Kingdom (S.B., C.D.A.B.)
Colin D. A. Brown
Department of Pharmaceutics, University of Washington, Seattle, Washington (V.K., J.Y., B.P., J.W., J.D.U.) and Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, United Kingdom (S.B., C.D.A.B.)
Joanne Wang
Department of Pharmaceutics, University of Washington, Seattle, Washington (V.K., J.Y., B.P., J.W., J.D.U.) and Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, United Kingdom (S.B., C.D.A.B.)
Jashvant D. Unadkat
Department of Pharmaceutics, University of Washington, Seattle, Washington (V.K., J.Y., B.P., J.W., J.D.U.) and Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, United Kingdom (S.B., C.D.A.B.)

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IVIVE of Renal Secretory Clearance of Metformin
Vineet Kumar, Jia Yin, Sarah Billington, Bhagwat Prasad, Colin D. A. Brown, Joanne Wang and Jashvant D. Unadkat
Drug Metabolism and Disposition October 1, 2018, 46 (10) 1441-1445; DOI: https://doi.org/10.1124/dmd.118.082313
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