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Retinal Cholesterol Content Is Reduced in Simvastatin-Treated Mice Due to Inhibited Local Biosynthesis Albeit Increased Uptake of Serum Cholesterol

Natalia Mast, Ilya R. Bederman and Irina A. Pikuleva
Drug Metabolism and Disposition November 2018, 46 (11) 1528-1537; DOI: https://doi.org/10.1124/dmd.118.083345

Article Information

vol. 46 no. 11 1528-1537
DOI 
https://doi.org/10.1124/dmd.118.083345
PubMed 
30115644
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 25, 2018
  • Accepted August 14, 2018
  • Published online October 12, 2018.

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Copyright & Usage 
Copyright © 2018 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Natalia Mast,
  2. Ilya R. Bederman, and
  3. Irina A. Pikuleva
  1. Departments of Ophthalmology and Visual Sciences (N.M., I.A.P.) and Pediatrics (I.R.B.), Case Western Reserve University, Cleveland, Ohio
  1. Address correspondence to:
    Dr. Irina A. Pikuleva, Department of Ophthalmology and Visual Sciences, Case Western Reserve University, 2085 Adelbert Road, Cleveland, OH 44106. E-mail: iap8{at}case.edu
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Statins and the Retina

Natalia Mast, Ilya R. Bederman and Irina A. Pikuleva
Drug Metabolism and Disposition November 1, 2018, 46 (11) 1528-1537; DOI: https://doi.org/10.1124/dmd.118.083345
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