Retinal Cholesterol Content Is Reduced in Simvastatin-Treated Mice Due to Inhibited Local Biosynthesis Albeit Increased Uptake of Serum Cholesterol

Natalia Mast; Ilya R. Bederman; Irina A. Pikuleva

doi:10.1124/dmd.118.083345

Research ArticleArticle

Retinal Cholesterol Content Is Reduced in Simvastatin-Treated Mice Due to Inhibited Local Biosynthesis Albeit Increased Uptake of Serum Cholesterol

Natalia Mast, Ilya R. Bederman and Irina A. Pikuleva

Drug Metabolism and Disposition November 2018, 46 (11) 1528-1537; DOI: https://doi.org/10.1124/dmd.118.083345

Natalia Mast

Departments of Ophthalmology and Visual Sciences (N.M., I.A.P.) and Pediatrics (I.R.B.), Case Western Reserve University, Cleveland, Ohio

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Ilya R. Bederman

Departments of Ophthalmology and Visual Sciences (N.M., I.A.P.) and Pediatrics (I.R.B.), Case Western Reserve University, Cleveland, Ohio

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Irina A. Pikuleva

Departments of Ophthalmology and Visual Sciences (N.M., I.A.P.) and Pediatrics (I.R.B.), Case Western Reserve University, Cleveland, Ohio

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Drug Metabolism and Disposition

Vol. 46, Issue 11

1 Nov 2018

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Research ArticleArticle

Statins and the Retina

Natalia Mast, Ilya R. Bederman and Irina A. Pikuleva

Drug Metabolism and Disposition November 1, 2018, 46 (11) 1528-1537; DOI: https://doi.org/10.1124/dmd.118.083345

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Research ArticleArticle

Statins and the Retina

Natalia Mast, Ilya R. Bederman and Irina A. Pikuleva

Drug Metabolism and Disposition November 1, 2018, 46 (11) 1528-1537; DOI: https://doi.org/10.1124/dmd.118.083345

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Retinal Cholesterol Content Is Reduced in Simvastatin-Treated Mice Due to Inhibited Local Biosynthesis Albeit Increased Uptake of Serum Cholesterol

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