Table of Contents

Articles

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  6-Chloro-5-[4-(1-Hydroxycyclobutyl)Phenyl]-1H-Indole-3-Carboxylic Acid is a Highly Selective Substrate for Glucuronidation by UGT1A1, Relative to β-Estradiol

  Kimberly Lapham, Jian Lin, Jonathan Novak, Christine Orozco, Mark Niosi, Li Di, Theunis C. Goosen, Sangwoo Ryu, Keith Riccardi, Heather Eng, Kimberly O. Cameron and Amit S. Kalgutkar

  Drug Metabolism and Disposition December 2018, 46 (12) 1836-1846; DOI: https://doi.org/10.1124/dmd.118.083709
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  Metabolism of c-Met Kinase Inhibitors Containing Quinoline by Aldehyde Oxidase, Electron Donating, and Steric Hindrance Effect

  Jiang Wei Zhang, Wen Xiao, Zhen Ting Gao, Zheng Tian Yu and Ji Yue (Jeff) Zhang

  Drug Metabolism and Disposition December 2018, 46 (12) 1847-1855; DOI: https://doi.org/10.1124/dmd.118.081919
• Open Access

  Calcitriol and Calcipotriol Modulate Transport Activity of ABC Transporters and Exhibit Selective Cytotoxicity in MRP1-overexpressing Cells

  Kee W. Tan, Angelina Sampson, Bremansu Osa-Andrews and Surtaj H. Iram

  Drug Metabolism and Disposition December 2018, 46 (12) 1856-1866; DOI: https://doi.org/10.1124/dmd.118.081612
• Open Access

  Identification and Quantification of Novel Major Metabolites of the Steroidal Aromatase Inhibitor, Exemestane

  Shaman Luo, Gang Chen, Cristina I. Truica, Cynthia C. Baird, Zuping Xia and Philip Lazarus

  Drug Metabolism and Disposition December 2018, 46 (12) 1867-1878; DOI: https://doi.org/10.1124/dmd.118.081166
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  Regional Differences in Human Intestinal Drug Metabolism

  Raditya Iswandana, Marina I. Irianti, Dorenda Oosterhuis, Hendrik S. Hofker, Marjolijn T. Merema, Marina H. de Jager, Henricus A. M. Mutsaers and Peter Olinga

  Drug Metabolism and Disposition December 2018, 46 (12) 1879-1885; DOI: https://doi.org/10.1124/dmd.118.083428
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  Toward a Combinatorial Approach for the Prediction of IgG Half-Life and Clearance

  Dennis R. Goulet, Michael J. Watson, Susan H. Tam, Adam Zwolak, Mark L. Chiu, William M. Atkins and Abhinav Nath

  Drug Metabolism and Disposition December 2018, 46 (12) 1900-1907; DOI: https://doi.org/10.1124/dmd.118.081893