Advertisement

Index by author

February 01, 2018; Volume 46,Issue 2

B

  1. Backman, Janne T.

    1. Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions 
      Helinä Kahma, Anne M. Filppula, Mikko Neuvonen, E. Katriina Tarkiainen, Aleksi Tornio, Mikko T. Holmberg, Matti K. Itkonen, Moshe Finel, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
      Drug Metabolism and Disposition February 2018, 46 (2) 141-150; DOI: https://doi.org/10.1124/dmd.117.078162

  2. Bhatt, Deepak Kumar

    1. Pregnancy Increases Norbuprenorphine Clearance in Mice by Induction of Hepatic Glucuronidation
      Michael Z. Liao, Chunying Gao, Brian R. Phillips, Naveen K. Neradugomma, Lyrialle W. Han, Deepak Kumar Bhatt, Bhagwat Prasad, Danny D. Shen and Qingcheng Mao
      Drug Metabolism and Disposition February 2018, 46 (2) 100-108; DOI: https://doi.org/10.1124/dmd.117.076745

  3. Billington, Sarah

    1. Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics
      Sarah Billington, Adrian S. Ray, Laurent Salphati, Guangqing Xiao, Xiaoyan Chu, W. Griffith Humphreys, Mingxiang Liao, Caroline A. Lee, Anita Mathias, Cornelis E. C. A. Hop, Christopher Rowbottom, Raymond Evers, Yurong Lai, Edward J. Kelly, Bhagwat Prasad and Jashvant D. Unadkat
      Drug Metabolism and Disposition February 2018, 46 (2) 189-196; DOI: https://doi.org/10.1124/dmd.117.077289

  4. Bischoff, Daniel

    1. Quantitative Expression of Hepatobiliary Transporters and Functional Uptake of Substrates in Hepatic Two-Dimensional Sandwich Cultures: A Comparative Evaluation of Upcyte and Primary Human Hepatocytes
      Michelle Schaefer, Gaku Morinaga, Akiko Matsui, Gerhard Schänzle, Daniel Bischoff and Roderich D. Süssmuth
      Drug Metabolism and Disposition February 2018, 46 (2) 166-177; DOI: https://doi.org/10.1124/dmd.117.078238

  5. Bruyère, Arnaud

    1. The JAK1/2 Inhibitor Ruxolitinib Reverses Interleukin-6-Mediated Suppression of Drug-Detoxifying Proteins in Cultured Human Hepatocytes
      Marie Febvre-James, Arnaud Bruyère, Marc Le Vée and Olivier Fardel
      Drug Metabolism and Disposition February 2018, 46 (2) 131-140; DOI: https://doi.org/10.1124/dmd.117.078048

  6. Burbacher, Thomas M.

    1. Toxicokinetics and Physiologically Based Pharmacokinetic Modeling of the Shellfish Toxin Domoic Acid in Nonhuman Primates
      Jing Jing, Rebekah Petroff, Sara Shum, Brenda Crouthamel, Ariel R. Topletz, Kimberly S. Grant, Thomas M. Burbacher and Nina Isoherranen
      Drug Metabolism and Disposition February 2018, 46 (2) 155-165; DOI: https://doi.org/10.1124/dmd.117.078485

C

  1. Chen, Weiqi

    1. Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys
      Hong Shen, David M. Nelson, Regina V. Oliveira, Yueping Zhang, Colleen A. Mcnaney, Xiaomei Gu, Weiqi Chen, Ching Su, Michael D. Reily, Petia A. Shipkova, Jinping Gan, Yurong Lai, Punit Marathe and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2018, 46 (2) 178-188; DOI: https://doi.org/10.1124/dmd.117.077586

  2. Choi, Min Sun

    1. Effect of Probiotics on Pharmacokinetics of Orally Administered Acetaminophen in Mice
      Jeon-Kyung Kim, Min Sun Choi, Jin-Ju Jeong, Su-Min Lim, In Sook Kim, Hye Hyun Yoo and Dong-Hyun Kim
      Drug Metabolism and Disposition February 2018, 46 (2) 122-130; DOI: https://doi.org/10.1124/dmd.117.077222

  3. Chu, Xiaoyan

    1. Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics
      Sarah Billington, Adrian S. Ray, Laurent Salphati, Guangqing Xiao, Xiaoyan Chu, W. Griffith Humphreys, Mingxiang Liao, Caroline A. Lee, Anita Mathias, Cornelis E. C. A. Hop, Christopher Rowbottom, Raymond Evers, Yurong Lai, Edward J. Kelly, Bhagwat Prasad and Jashvant D. Unadkat
      Drug Metabolism and Disposition February 2018, 46 (2) 189-196; DOI: https://doi.org/10.1124/dmd.117.077289

  4. Chun, Dung Yu

    1. Simultaneous Physiologically Based Pharmacokinetic (PBPK) Modeling of Parent and Active Metabolites to Investigate Complex CYP3A4 Drug-Drug Interaction Potential: A Case Example of Midostaurin
      Helen Gu, Catherine Dutreix, Sam Rebello, Taoufik Ouatas, Lai Wang, Dung Yu Chun, Heidi J. Einolf and Handan He
      Drug Metabolism and Disposition February 2018, 46 (2) 109-121; DOI: https://doi.org/10.1124/dmd.117.078006

  5. Crouthamel, Brenda

    1. Toxicokinetics and Physiologically Based Pharmacokinetic Modeling of the Shellfish Toxin Domoic Acid in Nonhuman Primates
      Jing Jing, Rebekah Petroff, Sara Shum, Brenda Crouthamel, Ariel R. Topletz, Kimberly S. Grant, Thomas M. Burbacher and Nina Isoherranen
      Drug Metabolism and Disposition February 2018, 46 (2) 155-165; DOI: https://doi.org/10.1124/dmd.117.078485

D

  1. Dutreix, Catherine

    1. Simultaneous Physiologically Based Pharmacokinetic (PBPK) Modeling of Parent and Active Metabolites to Investigate Complex CYP3A4 Drug-Drug Interaction Potential: A Case Example of Midostaurin
      Helen Gu, Catherine Dutreix, Sam Rebello, Taoufik Ouatas, Lai Wang, Dung Yu Chun, Heidi J. Einolf and Handan He
      Drug Metabolism and Disposition February 2018, 46 (2) 109-121; DOI: https://doi.org/10.1124/dmd.117.078006

  2. Duvvuri, Sridhar

    1. Estimation of Circulating Drug Metabolite Exposure in Human Using In Vitro Data and Physiologically Based Pharmacokinetic Modeling: Example of a High Metabolite/Parent Drug Ratio
      R. Scott Obach, Jian Lin, Emi Kimoto, Sridhar Duvvuri, Timothy Nicholas, Eugene P. Kadar, Larry M. Tremaine and Aarti Sawant-Basak
      Drug Metabolism and Disposition February 2018, 46 (2) 89-99; DOI: https://doi.org/10.1124/dmd.117.078279

E

  1. Einolf, Heidi J.

    1. Simultaneous Physiologically Based Pharmacokinetic (PBPK) Modeling of Parent and Active Metabolites to Investigate Complex CYP3A4 Drug-Drug Interaction Potential: A Case Example of Midostaurin
      Helen Gu, Catherine Dutreix, Sam Rebello, Taoufik Ouatas, Lai Wang, Dung Yu Chun, Heidi J. Einolf and Handan He
      Drug Metabolism and Disposition February 2018, 46 (2) 109-121; DOI: https://doi.org/10.1124/dmd.117.078006

  2. Evers, Raymond

    1. Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics
      Sarah Billington, Adrian S. Ray, Laurent Salphati, Guangqing Xiao, Xiaoyan Chu, W. Griffith Humphreys, Mingxiang Liao, Caroline A. Lee, Anita Mathias, Cornelis E. C. A. Hop, Christopher Rowbottom, Raymond Evers, Yurong Lai, Edward J. Kelly, Bhagwat Prasad and Jashvant D. Unadkat
      Drug Metabolism and Disposition February 2018, 46 (2) 189-196; DOI: https://doi.org/10.1124/dmd.117.077289

F

  1. Fardel, Olivier

    1. The JAK1/2 Inhibitor Ruxolitinib Reverses Interleukin-6-Mediated Suppression of Drug-Detoxifying Proteins in Cultured Human Hepatocytes
      Marie Febvre-James, Arnaud Bruyère, Marc Le Vée and Olivier Fardel
      Drug Metabolism and Disposition February 2018, 46 (2) 131-140; DOI: https://doi.org/10.1124/dmd.117.078048

  2. Febvre-James, Marie

    1. The JAK1/2 Inhibitor Ruxolitinib Reverses Interleukin-6-Mediated Suppression of Drug-Detoxifying Proteins in Cultured Human Hepatocytes
      Marie Febvre-James, Arnaud Bruyère, Marc Le Vée and Olivier Fardel
      Drug Metabolism and Disposition February 2018, 46 (2) 131-140; DOI: https://doi.org/10.1124/dmd.117.078048

  3. Filppula, Anne M.

    1. Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions 
      Helinä Kahma, Anne M. Filppula, Mikko Neuvonen, E. Katriina Tarkiainen, Aleksi Tornio, Mikko T. Holmberg, Matti K. Itkonen, Moshe Finel, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
      Drug Metabolism and Disposition February 2018, 46 (2) 141-150; DOI: https://doi.org/10.1124/dmd.117.078162

  4. Finel, Moshe

    1. Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions 
      Helinä Kahma, Anne M. Filppula, Mikko Neuvonen, E. Katriina Tarkiainen, Aleksi Tornio, Mikko T. Holmberg, Matti K. Itkonen, Moshe Finel, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
      Drug Metabolism and Disposition February 2018, 46 (2) 141-150; DOI: https://doi.org/10.1124/dmd.117.078162

G

  1. Gan, Jinping

    1. Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys
      Hong Shen, David M. Nelson, Regina V. Oliveira, Yueping Zhang, Colleen A. Mcnaney, Xiaomei Gu, Weiqi Chen, Ching Su, Michael D. Reily, Petia A. Shipkova, Jinping Gan, Yurong Lai, Punit Marathe and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2018, 46 (2) 178-188; DOI: https://doi.org/10.1124/dmd.117.077586

  2. Gao, Chunying

    1. Pregnancy Increases Norbuprenorphine Clearance in Mice by Induction of Hepatic Glucuronidation
      Michael Z. Liao, Chunying Gao, Brian R. Phillips, Naveen K. Neradugomma, Lyrialle W. Han, Deepak Kumar Bhatt, Bhagwat Prasad, Danny D. Shen and Qingcheng Mao
      Drug Metabolism and Disposition February 2018, 46 (2) 100-108; DOI: https://doi.org/10.1124/dmd.117.076745

  3. Grant, Kimberly S.

    1. Toxicokinetics and Physiologically Based Pharmacokinetic Modeling of the Shellfish Toxin Domoic Acid in Nonhuman Primates
      Jing Jing, Rebekah Petroff, Sara Shum, Brenda Crouthamel, Ariel R. Topletz, Kimberly S. Grant, Thomas M. Burbacher and Nina Isoherranen
      Drug Metabolism and Disposition February 2018, 46 (2) 155-165; DOI: https://doi.org/10.1124/dmd.117.078485

  4. Gu, Helen

    1. Simultaneous Physiologically Based Pharmacokinetic (PBPK) Modeling of Parent and Active Metabolites to Investigate Complex CYP3A4 Drug-Drug Interaction Potential: A Case Example of Midostaurin
      Helen Gu, Catherine Dutreix, Sam Rebello, Taoufik Ouatas, Lai Wang, Dung Yu Chun, Heidi J. Einolf and Handan He
      Drug Metabolism and Disposition February 2018, 46 (2) 109-121; DOI: https://doi.org/10.1124/dmd.117.078006

  5. Gu, Tong-Tong

    1. Mrp3 Transports Clopidogrel Acyl Glucuronide from the Hepatocytes into Blood
      Jin-Zi Ji, Ting Tai, Bei-Bei Huang, Tong-Tong Gu, Qiong-Yu Mi and Hong-Guang Xie
      Drug Metabolism and Disposition February 2018, 46 (2) 151-154; DOI: https://doi.org/10.1124/dmd.117.078329

  6. Gu, Xiaomei

    1. Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys
      Hong Shen, David M. Nelson, Regina V. Oliveira, Yueping Zhang, Colleen A. Mcnaney, Xiaomei Gu, Weiqi Chen, Ching Su, Michael D. Reily, Petia A. Shipkova, Jinping Gan, Yurong Lai, Punit Marathe and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2018, 46 (2) 178-188; DOI: https://doi.org/10.1124/dmd.117.077586

H

  1. Han, Lyrialle W.

    1. Pregnancy Increases Norbuprenorphine Clearance in Mice by Induction of Hepatic Glucuronidation
      Michael Z. Liao, Chunying Gao, Brian R. Phillips, Naveen K. Neradugomma, Lyrialle W. Han, Deepak Kumar Bhatt, Bhagwat Prasad, Danny D. Shen and Qingcheng Mao
      Drug Metabolism and Disposition February 2018, 46 (2) 100-108; DOI: https://doi.org/10.1124/dmd.117.076745

  2. He, Handan

    1. Simultaneous Physiologically Based Pharmacokinetic (PBPK) Modeling of Parent and Active Metabolites to Investigate Complex CYP3A4 Drug-Drug Interaction Potential: A Case Example of Midostaurin
      Helen Gu, Catherine Dutreix, Sam Rebello, Taoufik Ouatas, Lai Wang, Dung Yu Chun, Heidi J. Einolf and Handan He
      Drug Metabolism and Disposition February 2018, 46 (2) 109-121; DOI: https://doi.org/10.1124/dmd.117.078006

  3. Holmberg, Mikko T.

    1. Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions 
      Helinä Kahma, Anne M. Filppula, Mikko Neuvonen, E. Katriina Tarkiainen, Aleksi Tornio, Mikko T. Holmberg, Matti K. Itkonen, Moshe Finel, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
      Drug Metabolism and Disposition February 2018, 46 (2) 141-150; DOI: https://doi.org/10.1124/dmd.117.078162

  4. Hop, Cornelis E. C. A.

    1. Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics
      Sarah Billington, Adrian S. Ray, Laurent Salphati, Guangqing Xiao, Xiaoyan Chu, W. Griffith Humphreys, Mingxiang Liao, Caroline A. Lee, Anita Mathias, Cornelis E. C. A. Hop, Christopher Rowbottom, Raymond Evers, Yurong Lai, Edward J. Kelly, Bhagwat Prasad and Jashvant D. Unadkat
      Drug Metabolism and Disposition February 2018, 46 (2) 189-196; DOI: https://doi.org/10.1124/dmd.117.077289

  5. Huang, Bei-Bei

    1. Mrp3 Transports Clopidogrel Acyl Glucuronide from the Hepatocytes into Blood
      Jin-Zi Ji, Ting Tai, Bei-Bei Huang, Tong-Tong Gu, Qiong-Yu Mi and Hong-Guang Xie
      Drug Metabolism and Disposition February 2018, 46 (2) 151-154; DOI: https://doi.org/10.1124/dmd.117.078329

  6. Humphreys, W. Griffith

    1. Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys
      Hong Shen, David M. Nelson, Regina V. Oliveira, Yueping Zhang, Colleen A. Mcnaney, Xiaomei Gu, Weiqi Chen, Ching Su, Michael D. Reily, Petia A. Shipkova, Jinping Gan, Yurong Lai, Punit Marathe and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2018, 46 (2) 178-188; DOI: https://doi.org/10.1124/dmd.117.077586
    2. Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics
      Sarah Billington, Adrian S. Ray, Laurent Salphati, Guangqing Xiao, Xiaoyan Chu, W. Griffith Humphreys, Mingxiang Liao, Caroline A. Lee, Anita Mathias, Cornelis E. C. A. Hop, Christopher Rowbottom, Raymond Evers, Yurong Lai, Edward J. Kelly, Bhagwat Prasad and Jashvant D. Unadkat
      Drug Metabolism and Disposition February 2018, 46 (2) 189-196; DOI: https://doi.org/10.1124/dmd.117.077289

I

  1. Isoherranen, Nina

    1. Toxicokinetics and Physiologically Based Pharmacokinetic Modeling of the Shellfish Toxin Domoic Acid in Nonhuman Primates
      Jing Jing, Rebekah Petroff, Sara Shum, Brenda Crouthamel, Ariel R. Topletz, Kimberly S. Grant, Thomas M. Burbacher and Nina Isoherranen
      Drug Metabolism and Disposition February 2018, 46 (2) 155-165; DOI: https://doi.org/10.1124/dmd.117.078485

  2. Itkonen, Matti K.

    1. Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions 
      Helinä Kahma, Anne M. Filppula, Mikko Neuvonen, E. Katriina Tarkiainen, Aleksi Tornio, Mikko T. Holmberg, Matti K. Itkonen, Moshe Finel, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
      Drug Metabolism and Disposition February 2018, 46 (2) 141-150; DOI: https://doi.org/10.1124/dmd.117.078162

J

  1. Jeong, Jin-Ju

    1. Effect of Probiotics on Pharmacokinetics of Orally Administered Acetaminophen in Mice
      Jeon-Kyung Kim, Min Sun Choi, Jin-Ju Jeong, Su-Min Lim, In Sook Kim, Hye Hyun Yoo and Dong-Hyun Kim
      Drug Metabolism and Disposition February 2018, 46 (2) 122-130; DOI: https://doi.org/10.1124/dmd.117.077222

  2. Ji, Jin-Zi

    1. Mrp3 Transports Clopidogrel Acyl Glucuronide from the Hepatocytes into Blood
      Jin-Zi Ji, Ting Tai, Bei-Bei Huang, Tong-Tong Gu, Qiong-Yu Mi and Hong-Guang Xie
      Drug Metabolism and Disposition February 2018, 46 (2) 151-154; DOI: https://doi.org/10.1124/dmd.117.078329

  3. Jing, Jing

    1. Toxicokinetics and Physiologically Based Pharmacokinetic Modeling of the Shellfish Toxin Domoic Acid in Nonhuman Primates
      Jing Jing, Rebekah Petroff, Sara Shum, Brenda Crouthamel, Ariel R. Topletz, Kimberly S. Grant, Thomas M. Burbacher and Nina Isoherranen
      Drug Metabolism and Disposition February 2018, 46 (2) 155-165; DOI: https://doi.org/10.1124/dmd.117.078485

K

  1. Kadar, Eugene P.

    1. Estimation of Circulating Drug Metabolite Exposure in Human Using In Vitro Data and Physiologically Based Pharmacokinetic Modeling: Example of a High Metabolite/Parent Drug Ratio
      R. Scott Obach, Jian Lin, Emi Kimoto, Sridhar Duvvuri, Timothy Nicholas, Eugene P. Kadar, Larry M. Tremaine and Aarti Sawant-Basak
      Drug Metabolism and Disposition February 2018, 46 (2) 89-99; DOI: https://doi.org/10.1124/dmd.117.078279

  2. Kahma, Helinä

    1. Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions 
      Helinä Kahma, Anne M. Filppula, Mikko Neuvonen, E. Katriina Tarkiainen, Aleksi Tornio, Mikko T. Holmberg, Matti K. Itkonen, Moshe Finel, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
      Drug Metabolism and Disposition February 2018, 46 (2) 141-150; DOI: https://doi.org/10.1124/dmd.117.078162

  3. Kelly, Edward J.

    1. Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics
      Sarah Billington, Adrian S. Ray, Laurent Salphati, Guangqing Xiao, Xiaoyan Chu, W. Griffith Humphreys, Mingxiang Liao, Caroline A. Lee, Anita Mathias, Cornelis E. C. A. Hop, Christopher Rowbottom, Raymond Evers, Yurong Lai, Edward J. Kelly, Bhagwat Prasad and Jashvant D. Unadkat
      Drug Metabolism and Disposition February 2018, 46 (2) 189-196; DOI: https://doi.org/10.1124/dmd.117.077289

  4. Kim, Dong-Hyun

    1. Effect of Probiotics on Pharmacokinetics of Orally Administered Acetaminophen in Mice
      Jeon-Kyung Kim, Min Sun Choi, Jin-Ju Jeong, Su-Min Lim, In Sook Kim, Hye Hyun Yoo and Dong-Hyun Kim
      Drug Metabolism and Disposition February 2018, 46 (2) 122-130; DOI: https://doi.org/10.1124/dmd.117.077222

  5. Kim, In Sook

    1. Effect of Probiotics on Pharmacokinetics of Orally Administered Acetaminophen in Mice
      Jeon-Kyung Kim, Min Sun Choi, Jin-Ju Jeong, Su-Min Lim, In Sook Kim, Hye Hyun Yoo and Dong-Hyun Kim
      Drug Metabolism and Disposition February 2018, 46 (2) 122-130; DOI: https://doi.org/10.1124/dmd.117.077222

  6. Kim, Jeon-Kyung

    1. Effect of Probiotics on Pharmacokinetics of Orally Administered Acetaminophen in Mice
      Jeon-Kyung Kim, Min Sun Choi, Jin-Ju Jeong, Su-Min Lim, In Sook Kim, Hye Hyun Yoo and Dong-Hyun Kim
      Drug Metabolism and Disposition February 2018, 46 (2) 122-130; DOI: https://doi.org/10.1124/dmd.117.077222

  7. Kimoto, Emi

    1. Estimation of Circulating Drug Metabolite Exposure in Human Using In Vitro Data and Physiologically Based Pharmacokinetic Modeling: Example of a High Metabolite/Parent Drug Ratio
      R. Scott Obach, Jian Lin, Emi Kimoto, Sridhar Duvvuri, Timothy Nicholas, Eugene P. Kadar, Larry M. Tremaine and Aarti Sawant-Basak
      Drug Metabolism and Disposition February 2018, 46 (2) 89-99; DOI: https://doi.org/10.1124/dmd.117.078279

L

  1. Lai, Yurong

    1. Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys
      Hong Shen, David M. Nelson, Regina V. Oliveira, Yueping Zhang, Colleen A. Mcnaney, Xiaomei Gu, Weiqi Chen, Ching Su, Michael D. Reily, Petia A. Shipkova, Jinping Gan, Yurong Lai, Punit Marathe and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2018, 46 (2) 178-188; DOI: https://doi.org/10.1124/dmd.117.077586
    2. Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics
      Sarah Billington, Adrian S. Ray, Laurent Salphati, Guangqing Xiao, Xiaoyan Chu, W. Griffith Humphreys, Mingxiang Liao, Caroline A. Lee, Anita Mathias, Cornelis E. C. A. Hop, Christopher Rowbottom, Raymond Evers, Yurong Lai, Edward J. Kelly, Bhagwat Prasad and Jashvant D. Unadkat
      Drug Metabolism and Disposition February 2018, 46 (2) 189-196; DOI: https://doi.org/10.1124/dmd.117.077289

  2. Lee, Caroline A.

    1. Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics
      Sarah Billington, Adrian S. Ray, Laurent Salphati, Guangqing Xiao, Xiaoyan Chu, W. Griffith Humphreys, Mingxiang Liao, Caroline A. Lee, Anita Mathias, Cornelis E. C. A. Hop, Christopher Rowbottom, Raymond Evers, Yurong Lai, Edward J. Kelly, Bhagwat Prasad and Jashvant D. Unadkat
      Drug Metabolism and Disposition February 2018, 46 (2) 189-196; DOI: https://doi.org/10.1124/dmd.117.077289

  3. Le Vée, Marc

    1. The JAK1/2 Inhibitor Ruxolitinib Reverses Interleukin-6-Mediated Suppression of Drug-Detoxifying Proteins in Cultured Human Hepatocytes
      Marie Febvre-James, Arnaud Bruyère, Marc Le Vée and Olivier Fardel
      Drug Metabolism and Disposition February 2018, 46 (2) 131-140; DOI: https://doi.org/10.1124/dmd.117.078048

  4. Liao, Michael Z.

    1. Pregnancy Increases Norbuprenorphine Clearance in Mice by Induction of Hepatic Glucuronidation
      Michael Z. Liao, Chunying Gao, Brian R. Phillips, Naveen K. Neradugomma, Lyrialle W. Han, Deepak Kumar Bhatt, Bhagwat Prasad, Danny D. Shen and Qingcheng Mao
      Drug Metabolism and Disposition February 2018, 46 (2) 100-108; DOI: https://doi.org/10.1124/dmd.117.076745

  5. Liao, Mingxiang

    1. Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics
      Sarah Billington, Adrian S. Ray, Laurent Salphati, Guangqing Xiao, Xiaoyan Chu, W. Griffith Humphreys, Mingxiang Liao, Caroline A. Lee, Anita Mathias, Cornelis E. C. A. Hop, Christopher Rowbottom, Raymond Evers, Yurong Lai, Edward J. Kelly, Bhagwat Prasad and Jashvant D. Unadkat
      Drug Metabolism and Disposition February 2018, 46 (2) 189-196; DOI: https://doi.org/10.1124/dmd.117.077289

  6. Lim, Su-Min

    1. Effect of Probiotics on Pharmacokinetics of Orally Administered Acetaminophen in Mice
      Jeon-Kyung Kim, Min Sun Choi, Jin-Ju Jeong, Su-Min Lim, In Sook Kim, Hye Hyun Yoo and Dong-Hyun Kim
      Drug Metabolism and Disposition February 2018, 46 (2) 122-130; DOI: https://doi.org/10.1124/dmd.117.077222

  7. Lin, Jian

    1. Estimation of Circulating Drug Metabolite Exposure in Human Using In Vitro Data and Physiologically Based Pharmacokinetic Modeling: Example of a High Metabolite/Parent Drug Ratio
      R. Scott Obach, Jian Lin, Emi Kimoto, Sridhar Duvvuri, Timothy Nicholas, Eugene P. Kadar, Larry M. Tremaine and Aarti Sawant-Basak
      Drug Metabolism and Disposition February 2018, 46 (2) 89-99; DOI: https://doi.org/10.1124/dmd.117.078279

M

  1. Mao, Qingcheng

    1. Pregnancy Increases Norbuprenorphine Clearance in Mice by Induction of Hepatic Glucuronidation
      Michael Z. Liao, Chunying Gao, Brian R. Phillips, Naveen K. Neradugomma, Lyrialle W. Han, Deepak Kumar Bhatt, Bhagwat Prasad, Danny D. Shen and Qingcheng Mao
      Drug Metabolism and Disposition February 2018, 46 (2) 100-108; DOI: https://doi.org/10.1124/dmd.117.076745

  2. Marathe, Punit

    1. Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys
      Hong Shen, David M. Nelson, Regina V. Oliveira, Yueping Zhang, Colleen A. Mcnaney, Xiaomei Gu, Weiqi Chen, Ching Su, Michael D. Reily, Petia A. Shipkova, Jinping Gan, Yurong Lai, Punit Marathe and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2018, 46 (2) 178-188; DOI: https://doi.org/10.1124/dmd.117.077586

  3. Mathias, Anita

    1. Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics
      Sarah Billington, Adrian S. Ray, Laurent Salphati, Guangqing Xiao, Xiaoyan Chu, W. Griffith Humphreys, Mingxiang Liao, Caroline A. Lee, Anita Mathias, Cornelis E. C. A. Hop, Christopher Rowbottom, Raymond Evers, Yurong Lai, Edward J. Kelly, Bhagwat Prasad and Jashvant D. Unadkat
      Drug Metabolism and Disposition February 2018, 46 (2) 189-196; DOI: https://doi.org/10.1124/dmd.117.077289

  4. Matsui, Akiko

    1. Quantitative Expression of Hepatobiliary Transporters and Functional Uptake of Substrates in Hepatic Two-Dimensional Sandwich Cultures: A Comparative Evaluation of Upcyte and Primary Human Hepatocytes
      Michelle Schaefer, Gaku Morinaga, Akiko Matsui, Gerhard Schänzle, Daniel Bischoff and Roderich D. Süssmuth
      Drug Metabolism and Disposition February 2018, 46 (2) 166-177; DOI: https://doi.org/10.1124/dmd.117.078238

  5. Mcnaney, Colleen A.

    1. Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys
      Hong Shen, David M. Nelson, Regina V. Oliveira, Yueping Zhang, Colleen A. Mcnaney, Xiaomei Gu, Weiqi Chen, Ching Su, Michael D. Reily, Petia A. Shipkova, Jinping Gan, Yurong Lai, Punit Marathe and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2018, 46 (2) 178-188; DOI: https://doi.org/10.1124/dmd.117.077586

  6. Mi, Qiong-Yu

    1. Mrp3 Transports Clopidogrel Acyl Glucuronide from the Hepatocytes into Blood
      Jin-Zi Ji, Ting Tai, Bei-Bei Huang, Tong-Tong Gu, Qiong-Yu Mi and Hong-Guang Xie
      Drug Metabolism and Disposition February 2018, 46 (2) 151-154; DOI: https://doi.org/10.1124/dmd.117.078329

  7. Morinaga, Gaku

    1. Quantitative Expression of Hepatobiliary Transporters and Functional Uptake of Substrates in Hepatic Two-Dimensional Sandwich Cultures: A Comparative Evaluation of Upcyte and Primary Human Hepatocytes
      Michelle Schaefer, Gaku Morinaga, Akiko Matsui, Gerhard Schänzle, Daniel Bischoff and Roderich D. Süssmuth
      Drug Metabolism and Disposition February 2018, 46 (2) 166-177; DOI: https://doi.org/10.1124/dmd.117.078238

N

  1. Nelson, David M.

    1. Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys
      Hong Shen, David M. Nelson, Regina V. Oliveira, Yueping Zhang, Colleen A. Mcnaney, Xiaomei Gu, Weiqi Chen, Ching Su, Michael D. Reily, Petia A. Shipkova, Jinping Gan, Yurong Lai, Punit Marathe and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2018, 46 (2) 178-188; DOI: https://doi.org/10.1124/dmd.117.077586

  2. Neradugomma, Naveen K.

    1. Pregnancy Increases Norbuprenorphine Clearance in Mice by Induction of Hepatic Glucuronidation
      Michael Z. Liao, Chunying Gao, Brian R. Phillips, Naveen K. Neradugomma, Lyrialle W. Han, Deepak Kumar Bhatt, Bhagwat Prasad, Danny D. Shen and Qingcheng Mao
      Drug Metabolism and Disposition February 2018, 46 (2) 100-108; DOI: https://doi.org/10.1124/dmd.117.076745

  3. Neuvonen, Mikko

    1. Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions 
      Helinä Kahma, Anne M. Filppula, Mikko Neuvonen, E. Katriina Tarkiainen, Aleksi Tornio, Mikko T. Holmberg, Matti K. Itkonen, Moshe Finel, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
      Drug Metabolism and Disposition February 2018, 46 (2) 141-150; DOI: https://doi.org/10.1124/dmd.117.078162

  4. Neuvonen, Pertti J.

    1. Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions 
      Helinä Kahma, Anne M. Filppula, Mikko Neuvonen, E. Katriina Tarkiainen, Aleksi Tornio, Mikko T. Holmberg, Matti K. Itkonen, Moshe Finel, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
      Drug Metabolism and Disposition February 2018, 46 (2) 141-150; DOI: https://doi.org/10.1124/dmd.117.078162

  5. Nicholas, Timothy

    1. Estimation of Circulating Drug Metabolite Exposure in Human Using In Vitro Data and Physiologically Based Pharmacokinetic Modeling: Example of a High Metabolite/Parent Drug Ratio
      R. Scott Obach, Jian Lin, Emi Kimoto, Sridhar Duvvuri, Timothy Nicholas, Eugene P. Kadar, Larry M. Tremaine and Aarti Sawant-Basak
      Drug Metabolism and Disposition February 2018, 46 (2) 89-99; DOI: https://doi.org/10.1124/dmd.117.078279

  6. Niemi, Mikko

    1. Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions 
      Helinä Kahma, Anne M. Filppula, Mikko Neuvonen, E. Katriina Tarkiainen, Aleksi Tornio, Mikko T. Holmberg, Matti K. Itkonen, Moshe Finel, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
      Drug Metabolism and Disposition February 2018, 46 (2) 141-150; DOI: https://doi.org/10.1124/dmd.117.078162

O

  1. Obach, R. Scott

    1. Estimation of Circulating Drug Metabolite Exposure in Human Using In Vitro Data and Physiologically Based Pharmacokinetic Modeling: Example of a High Metabolite/Parent Drug Ratio
      R. Scott Obach, Jian Lin, Emi Kimoto, Sridhar Duvvuri, Timothy Nicholas, Eugene P. Kadar, Larry M. Tremaine and Aarti Sawant-Basak
      Drug Metabolism and Disposition February 2018, 46 (2) 89-99; DOI: https://doi.org/10.1124/dmd.117.078279

  2. Oliveira, Regina V.

    1. Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys
      Hong Shen, David M. Nelson, Regina V. Oliveira, Yueping Zhang, Colleen A. Mcnaney, Xiaomei Gu, Weiqi Chen, Ching Su, Michael D. Reily, Petia A. Shipkova, Jinping Gan, Yurong Lai, Punit Marathe and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2018, 46 (2) 178-188; DOI: https://doi.org/10.1124/dmd.117.077586

  3. Ouatas, Taoufik

    1. Simultaneous Physiologically Based Pharmacokinetic (PBPK) Modeling of Parent and Active Metabolites to Investigate Complex CYP3A4 Drug-Drug Interaction Potential: A Case Example of Midostaurin
      Helen Gu, Catherine Dutreix, Sam Rebello, Taoufik Ouatas, Lai Wang, Dung Yu Chun, Heidi J. Einolf and Handan He
      Drug Metabolism and Disposition February 2018, 46 (2) 109-121; DOI: https://doi.org/10.1124/dmd.117.078006

P

  1. Petroff, Rebekah

    1. Toxicokinetics and Physiologically Based Pharmacokinetic Modeling of the Shellfish Toxin Domoic Acid in Nonhuman Primates
      Jing Jing, Rebekah Petroff, Sara Shum, Brenda Crouthamel, Ariel R. Topletz, Kimberly S. Grant, Thomas M. Burbacher and Nina Isoherranen
      Drug Metabolism and Disposition February 2018, 46 (2) 155-165; DOI: https://doi.org/10.1124/dmd.117.078485

  2. Phillips, Brian R.

    1. Pregnancy Increases Norbuprenorphine Clearance in Mice by Induction of Hepatic Glucuronidation
      Michael Z. Liao, Chunying Gao, Brian R. Phillips, Naveen K. Neradugomma, Lyrialle W. Han, Deepak Kumar Bhatt, Bhagwat Prasad, Danny D. Shen and Qingcheng Mao
      Drug Metabolism and Disposition February 2018, 46 (2) 100-108; DOI: https://doi.org/10.1124/dmd.117.076745

  3. Prasad, Bhagwat

    1. Pregnancy Increases Norbuprenorphine Clearance in Mice by Induction of Hepatic Glucuronidation
      Michael Z. Liao, Chunying Gao, Brian R. Phillips, Naveen K. Neradugomma, Lyrialle W. Han, Deepak Kumar Bhatt, Bhagwat Prasad, Danny D. Shen and Qingcheng Mao
      Drug Metabolism and Disposition February 2018, 46 (2) 100-108; DOI: https://doi.org/10.1124/dmd.117.076745
    2. Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics
      Sarah Billington, Adrian S. Ray, Laurent Salphati, Guangqing Xiao, Xiaoyan Chu, W. Griffith Humphreys, Mingxiang Liao, Caroline A. Lee, Anita Mathias, Cornelis E. C. A. Hop, Christopher Rowbottom, Raymond Evers, Yurong Lai, Edward J. Kelly, Bhagwat Prasad and Jashvant D. Unadkat
      Drug Metabolism and Disposition February 2018, 46 (2) 189-196; DOI: https://doi.org/10.1124/dmd.117.077289

R

  1. Ray, Adrian S.

    1. Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics
      Sarah Billington, Adrian S. Ray, Laurent Salphati, Guangqing Xiao, Xiaoyan Chu, W. Griffith Humphreys, Mingxiang Liao, Caroline A. Lee, Anita Mathias, Cornelis E. C. A. Hop, Christopher Rowbottom, Raymond Evers, Yurong Lai, Edward J. Kelly, Bhagwat Prasad and Jashvant D. Unadkat
      Drug Metabolism and Disposition February 2018, 46 (2) 189-196; DOI: https://doi.org/10.1124/dmd.117.077289

  2. Rebello, Sam

    1. Simultaneous Physiologically Based Pharmacokinetic (PBPK) Modeling of Parent and Active Metabolites to Investigate Complex CYP3A4 Drug-Drug Interaction Potential: A Case Example of Midostaurin
      Helen Gu, Catherine Dutreix, Sam Rebello, Taoufik Ouatas, Lai Wang, Dung Yu Chun, Heidi J. Einolf and Handan He
      Drug Metabolism and Disposition February 2018, 46 (2) 109-121; DOI: https://doi.org/10.1124/dmd.117.078006

  3. Reily, Michael D.

    1. Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys
      Hong Shen, David M. Nelson, Regina V. Oliveira, Yueping Zhang, Colleen A. Mcnaney, Xiaomei Gu, Weiqi Chen, Ching Su, Michael D. Reily, Petia A. Shipkova, Jinping Gan, Yurong Lai, Punit Marathe and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2018, 46 (2) 178-188; DOI: https://doi.org/10.1124/dmd.117.077586

  4. Rowbottom, Christopher

    1. Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics
      Sarah Billington, Adrian S. Ray, Laurent Salphati, Guangqing Xiao, Xiaoyan Chu, W. Griffith Humphreys, Mingxiang Liao, Caroline A. Lee, Anita Mathias, Cornelis E. C. A. Hop, Christopher Rowbottom, Raymond Evers, Yurong Lai, Edward J. Kelly, Bhagwat Prasad and Jashvant D. Unadkat
      Drug Metabolism and Disposition February 2018, 46 (2) 189-196; DOI: https://doi.org/10.1124/dmd.117.077289

S

  1. Salphati, Laurent

    1. Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics
      Sarah Billington, Adrian S. Ray, Laurent Salphati, Guangqing Xiao, Xiaoyan Chu, W. Griffith Humphreys, Mingxiang Liao, Caroline A. Lee, Anita Mathias, Cornelis E. C. A. Hop, Christopher Rowbottom, Raymond Evers, Yurong Lai, Edward J. Kelly, Bhagwat Prasad and Jashvant D. Unadkat
      Drug Metabolism and Disposition February 2018, 46 (2) 189-196; DOI: https://doi.org/10.1124/dmd.117.077289

  2. Sawant-Basak, Aarti

    1. Estimation of Circulating Drug Metabolite Exposure in Human Using In Vitro Data and Physiologically Based Pharmacokinetic Modeling: Example of a High Metabolite/Parent Drug Ratio
      R. Scott Obach, Jian Lin, Emi Kimoto, Sridhar Duvvuri, Timothy Nicholas, Eugene P. Kadar, Larry M. Tremaine and Aarti Sawant-Basak
      Drug Metabolism and Disposition February 2018, 46 (2) 89-99; DOI: https://doi.org/10.1124/dmd.117.078279

  3. Schaefer, Michelle

    1. Quantitative Expression of Hepatobiliary Transporters and Functional Uptake of Substrates in Hepatic Two-Dimensional Sandwich Cultures: A Comparative Evaluation of Upcyte and Primary Human Hepatocytes
      Michelle Schaefer, Gaku Morinaga, Akiko Matsui, Gerhard Schänzle, Daniel Bischoff and Roderich D. Süssmuth
      Drug Metabolism and Disposition February 2018, 46 (2) 166-177; DOI: https://doi.org/10.1124/dmd.117.078238

  4. Schänzle, Gerhard

    1. Quantitative Expression of Hepatobiliary Transporters and Functional Uptake of Substrates in Hepatic Two-Dimensional Sandwich Cultures: A Comparative Evaluation of Upcyte and Primary Human Hepatocytes
      Michelle Schaefer, Gaku Morinaga, Akiko Matsui, Gerhard Schänzle, Daniel Bischoff and Roderich D. Süssmuth
      Drug Metabolism and Disposition February 2018, 46 (2) 166-177; DOI: https://doi.org/10.1124/dmd.117.078238

  5. Shen, Danny D.

    1. Pregnancy Increases Norbuprenorphine Clearance in Mice by Induction of Hepatic Glucuronidation
      Michael Z. Liao, Chunying Gao, Brian R. Phillips, Naveen K. Neradugomma, Lyrialle W. Han, Deepak Kumar Bhatt, Bhagwat Prasad, Danny D. Shen and Qingcheng Mao
      Drug Metabolism and Disposition February 2018, 46 (2) 100-108; DOI: https://doi.org/10.1124/dmd.117.076745

  6. Shen, Hong

    1. Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys
      Hong Shen, David M. Nelson, Regina V. Oliveira, Yueping Zhang, Colleen A. Mcnaney, Xiaomei Gu, Weiqi Chen, Ching Su, Michael D. Reily, Petia A. Shipkova, Jinping Gan, Yurong Lai, Punit Marathe and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2018, 46 (2) 178-188; DOI: https://doi.org/10.1124/dmd.117.077586

  7. Shipkova, Petia A.

    1. Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys
      Hong Shen, David M. Nelson, Regina V. Oliveira, Yueping Zhang, Colleen A. Mcnaney, Xiaomei Gu, Weiqi Chen, Ching Su, Michael D. Reily, Petia A. Shipkova, Jinping Gan, Yurong Lai, Punit Marathe and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2018, 46 (2) 178-188; DOI: https://doi.org/10.1124/dmd.117.077586

  8. Shum, Sara

    1. Toxicokinetics and Physiologically Based Pharmacokinetic Modeling of the Shellfish Toxin Domoic Acid in Nonhuman Primates
      Jing Jing, Rebekah Petroff, Sara Shum, Brenda Crouthamel, Ariel R. Topletz, Kimberly S. Grant, Thomas M. Burbacher and Nina Isoherranen
      Drug Metabolism and Disposition February 2018, 46 (2) 155-165; DOI: https://doi.org/10.1124/dmd.117.078485

  9. Stevens, Jeffrey C.

    1. Editorial
      Jeffrey C. Stevens
      Drug Metabolism and Disposition February 2018, 46 (2) 88; DOI: https://doi.org/10.1124/dmd.117.079772

  10. Su, Ching

    1. Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys
      Hong Shen, David M. Nelson, Regina V. Oliveira, Yueping Zhang, Colleen A. Mcnaney, Xiaomei Gu, Weiqi Chen, Ching Su, Michael D. Reily, Petia A. Shipkova, Jinping Gan, Yurong Lai, Punit Marathe and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2018, 46 (2) 178-188; DOI: https://doi.org/10.1124/dmd.117.077586

  11. Süssmuth, Roderich D.

    1. Quantitative Expression of Hepatobiliary Transporters and Functional Uptake of Substrates in Hepatic Two-Dimensional Sandwich Cultures: A Comparative Evaluation of Upcyte and Primary Human Hepatocytes
      Michelle Schaefer, Gaku Morinaga, Akiko Matsui, Gerhard Schänzle, Daniel Bischoff and Roderich D. Süssmuth
      Drug Metabolism and Disposition February 2018, 46 (2) 166-177; DOI: https://doi.org/10.1124/dmd.117.078238

T

  1. Tai, Ting

    1. Mrp3 Transports Clopidogrel Acyl Glucuronide from the Hepatocytes into Blood
      Jin-Zi Ji, Ting Tai, Bei-Bei Huang, Tong-Tong Gu, Qiong-Yu Mi and Hong-Guang Xie
      Drug Metabolism and Disposition February 2018, 46 (2) 151-154; DOI: https://doi.org/10.1124/dmd.117.078329

  2. Tarkiainen, E. Katriina

    1. Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions 
      Helinä Kahma, Anne M. Filppula, Mikko Neuvonen, E. Katriina Tarkiainen, Aleksi Tornio, Mikko T. Holmberg, Matti K. Itkonen, Moshe Finel, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
      Drug Metabolism and Disposition February 2018, 46 (2) 141-150; DOI: https://doi.org/10.1124/dmd.117.078162

  3. Topletz, Ariel R.

    1. Toxicokinetics and Physiologically Based Pharmacokinetic Modeling of the Shellfish Toxin Domoic Acid in Nonhuman Primates
      Jing Jing, Rebekah Petroff, Sara Shum, Brenda Crouthamel, Ariel R. Topletz, Kimberly S. Grant, Thomas M. Burbacher and Nina Isoherranen
      Drug Metabolism and Disposition February 2018, 46 (2) 155-165; DOI: https://doi.org/10.1124/dmd.117.078485

  4. Tornio, Aleksi

    1. Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions 
      Helinä Kahma, Anne M. Filppula, Mikko Neuvonen, E. Katriina Tarkiainen, Aleksi Tornio, Mikko T. Holmberg, Matti K. Itkonen, Moshe Finel, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
      Drug Metabolism and Disposition February 2018, 46 (2) 141-150; DOI: https://doi.org/10.1124/dmd.117.078162

  5. Tremaine, Larry M.

    1. Estimation of Circulating Drug Metabolite Exposure in Human Using In Vitro Data and Physiologically Based Pharmacokinetic Modeling: Example of a High Metabolite/Parent Drug Ratio
      R. Scott Obach, Jian Lin, Emi Kimoto, Sridhar Duvvuri, Timothy Nicholas, Eugene P. Kadar, Larry M. Tremaine and Aarti Sawant-Basak
      Drug Metabolism and Disposition February 2018, 46 (2) 89-99; DOI: https://doi.org/10.1124/dmd.117.078279

U

  1. Unadkat, Jashvant D.

    1. Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics
      Sarah Billington, Adrian S. Ray, Laurent Salphati, Guangqing Xiao, Xiaoyan Chu, W. Griffith Humphreys, Mingxiang Liao, Caroline A. Lee, Anita Mathias, Cornelis E. C. A. Hop, Christopher Rowbottom, Raymond Evers, Yurong Lai, Edward J. Kelly, Bhagwat Prasad and Jashvant D. Unadkat
      Drug Metabolism and Disposition February 2018, 46 (2) 189-196; DOI: https://doi.org/10.1124/dmd.117.077289

W

  1. Wang, Lai

    1. Simultaneous Physiologically Based Pharmacokinetic (PBPK) Modeling of Parent and Active Metabolites to Investigate Complex CYP3A4 Drug-Drug Interaction Potential: A Case Example of Midostaurin
      Helen Gu, Catherine Dutreix, Sam Rebello, Taoufik Ouatas, Lai Wang, Dung Yu Chun, Heidi J. Einolf and Handan He
      Drug Metabolism and Disposition February 2018, 46 (2) 109-121; DOI: https://doi.org/10.1124/dmd.117.078006

X

  1. Xiao, Guangqing

    1. Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics
      Sarah Billington, Adrian S. Ray, Laurent Salphati, Guangqing Xiao, Xiaoyan Chu, W. Griffith Humphreys, Mingxiang Liao, Caroline A. Lee, Anita Mathias, Cornelis E. C. A. Hop, Christopher Rowbottom, Raymond Evers, Yurong Lai, Edward J. Kelly, Bhagwat Prasad and Jashvant D. Unadkat
      Drug Metabolism and Disposition February 2018, 46 (2) 189-196; DOI: https://doi.org/10.1124/dmd.117.077289

  2. Xie, Hong-Guang

    1. Mrp3 Transports Clopidogrel Acyl Glucuronide from the Hepatocytes into Blood
      Jin-Zi Ji, Ting Tai, Bei-Bei Huang, Tong-Tong Gu, Qiong-Yu Mi and Hong-Guang Xie
      Drug Metabolism and Disposition February 2018, 46 (2) 151-154; DOI: https://doi.org/10.1124/dmd.117.078329

Y

  1. Yoo, Hye Hyun

    1. Effect of Probiotics on Pharmacokinetics of Orally Administered Acetaminophen in Mice
      Jeon-Kyung Kim, Min Sun Choi, Jin-Ju Jeong, Su-Min Lim, In Sook Kim, Hye Hyun Yoo and Dong-Hyun Kim
      Drug Metabolism and Disposition February 2018, 46 (2) 122-130; DOI: https://doi.org/10.1124/dmd.117.077222

Z

  1. Zhang, Yueping

    1. Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys
      Hong Shen, David M. Nelson, Regina V. Oliveira, Yueping Zhang, Colleen A. Mcnaney, Xiaomei Gu, Weiqi Chen, Ching Su, Michael D. Reily, Petia A. Shipkova, Jinping Gan, Yurong Lai, Punit Marathe and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2018, 46 (2) 178-188; DOI: https://doi.org/10.1124/dmd.117.077586
Back to top

In this issue