Drug Metabolism and Disposition: 46 (3)

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About the cover: Confocal immunofluorescence microscopic analysis of BCRP protein localization in pancreatic cancer cell lines and MDCKII cells. See the article by Tamai et al., (https://doi.org/10.1124/dmd.117.078402)

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Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUC_I/AUC) RATIOS
In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model

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