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Drug Metabolism & Disposition

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  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
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Index by author

March 01, 2018; Volume 46,Issue 3
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Artelsmair, Markus

    1. Open Access
      Late-occurring and Long-circulating Metabolites of GABAAα2,3 Receptor Modulator AZD7325 Involving Metabolic Cyclization and Aromatization: Relevance to MIST Analysis and Application for Patient Compliance
      Chungang Gu, Markus Artelsmair, Charles S. Elmore, Richard J. Lewis, Patty Davis, James E. Hall, Bruce T. Dembofsky, Greg Christoph, Mark A. Smith, Marc Chapdelaine and Maria Sunzel
      Drug Metabolism and Disposition March 2018, 46 (3) 303-315; DOI: https://doi.org/10.1124/dmd.117.078873
  2. Asahi, Satoru

    1. You have access
      Mechanism for Covalent Binding of MLN3126, an Oral Chemokine C-C Motif Receptor 9 Antagonist, to Serum Albumins
      Naohiro Narita, Akio Morohashi, Kimio Tohyama, Toshiyuki Takeuchi, Yoshihiko Tagawa, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition March 2018, 46 (3) 204-213; DOI: https://doi.org/10.1124/dmd.117.078782

B

  1. Backes, Wayne L.

    1. You have access
      Characterization of Interactions Among CYP1A2, CYP2B4, and NADPH-cytochrome P450 Reductase: Identification of Specific Protein Complexes
      J. Patrick Connick, James R. Reed and Wayne L. Backes
      Drug Metabolism and Disposition March 2018, 46 (3) 197-203; DOI: https://doi.org/10.1124/dmd.117.078642
  2. Bentz, Joe

    1. You have access
      Derivation of a System-Independent Ki for P-glycoprotein Mediated Digoxin Transport from System-Dependent IC50 Data
      Aqsaa Chaudhry, Git Chung, Adam Lynn, Akshata Yalvigi, Colin Brown, Harma Ellens, Michael O’Connor, Caroline Lee and Joe Bentz
      Drug Metabolism and Disposition March 2018, 46 (3) 279-290; DOI: https://doi.org/10.1124/dmd.117.075606
  3. Briolotti, Philippe

    1. You have access
      Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor
      Hugues de Boussac, Claire Gondeau, Philippe Briolotti, Cédric Duret, Fridolin Treindl, Michael Römer, Jean-Michel Fabre, Astrid Herrero, Jeanne Ramos, Patrick Maurel, Markus Templin, Sabine Gerbal-Chaloin and Martine Daujat-Chavanieu
      Drug Metabolism and Disposition March 2018, 46 (3) 223-236; DOI: https://doi.org/10.1124/dmd.117.078683
  4. Brown, Colin

    1. You have access
      Derivation of a System-Independent Ki for P-glycoprotein Mediated Digoxin Transport from System-Dependent IC50 Data
      Aqsaa Chaudhry, Git Chung, Adam Lynn, Akshata Yalvigi, Colin Brown, Harma Ellens, Michael O’Connor, Caroline Lee and Joe Bentz
      Drug Metabolism and Disposition March 2018, 46 (3) 279-290; DOI: https://doi.org/10.1124/dmd.117.075606

C

  1. Chapdelaine, Marc

    1. Open Access
      Late-occurring and Long-circulating Metabolites of GABAAα2,3 Receptor Modulator AZD7325 Involving Metabolic Cyclization and Aromatization: Relevance to MIST Analysis and Application for Patient Compliance
      Chungang Gu, Markus Artelsmair, Charles S. Elmore, Richard J. Lewis, Patty Davis, James E. Hall, Bruce T. Dembofsky, Greg Christoph, Mark A. Smith, Marc Chapdelaine and Maria Sunzel
      Drug Metabolism and Disposition March 2018, 46 (3) 303-315; DOI: https://doi.org/10.1124/dmd.117.078873
  2. Chaudhry, Aqsaa

    1. You have access
      Derivation of a System-Independent Ki for P-glycoprotein Mediated Digoxin Transport from System-Dependent IC50 Data
      Aqsaa Chaudhry, Git Chung, Adam Lynn, Akshata Yalvigi, Colin Brown, Harma Ellens, Michael O’Connor, Caroline Lee and Joe Bentz
      Drug Metabolism and Disposition March 2018, 46 (3) 279-290; DOI: https://doi.org/10.1124/dmd.117.075606
  3. Christoph, Greg

    1. Open Access
      Late-occurring and Long-circulating Metabolites of GABAAα2,3 Receptor Modulator AZD7325 Involving Metabolic Cyclization and Aromatization: Relevance to MIST Analysis and Application for Patient Compliance
      Chungang Gu, Markus Artelsmair, Charles S. Elmore, Richard J. Lewis, Patty Davis, James E. Hall, Bruce T. Dembofsky, Greg Christoph, Mark A. Smith, Marc Chapdelaine and Maria Sunzel
      Drug Metabolism and Disposition March 2018, 46 (3) 303-315; DOI: https://doi.org/10.1124/dmd.117.078873
  4. Chung, Git

    1. You have access
      Derivation of a System-Independent Ki for P-glycoprotein Mediated Digoxin Transport from System-Dependent IC50 Data
      Aqsaa Chaudhry, Git Chung, Adam Lynn, Akshata Yalvigi, Colin Brown, Harma Ellens, Michael O’Connor, Caroline Lee and Joe Bentz
      Drug Metabolism and Disposition March 2018, 46 (3) 279-290; DOI: https://doi.org/10.1124/dmd.117.075606
  5. Connick, J. Patrick

    1. You have access
      Characterization of Interactions Among CYP1A2, CYP2B4, and NADPH-cytochrome P450 Reductase: Identification of Specific Protein Complexes
      J. Patrick Connick, James R. Reed and Wayne L. Backes
      Drug Metabolism and Disposition March 2018, 46 (3) 197-203; DOI: https://doi.org/10.1124/dmd.117.078642

D

  1. Daujat-Chavanieu, Martine

    1. You have access
      Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor
      Hugues de Boussac, Claire Gondeau, Philippe Briolotti, Cédric Duret, Fridolin Treindl, Michael Römer, Jean-Michel Fabre, Astrid Herrero, Jeanne Ramos, Patrick Maurel, Markus Templin, Sabine Gerbal-Chaloin and Martine Daujat-Chavanieu
      Drug Metabolism and Disposition March 2018, 46 (3) 223-236; DOI: https://doi.org/10.1124/dmd.117.078683
  2. Davis, Patty

    1. Open Access
      Late-occurring and Long-circulating Metabolites of GABAAα2,3 Receptor Modulator AZD7325 Involving Metabolic Cyclization and Aromatization: Relevance to MIST Analysis and Application for Patient Compliance
      Chungang Gu, Markus Artelsmair, Charles S. Elmore, Richard J. Lewis, Patty Davis, James E. Hall, Bruce T. Dembofsky, Greg Christoph, Mark A. Smith, Marc Chapdelaine and Maria Sunzel
      Drug Metabolism and Disposition March 2018, 46 (3) 303-315; DOI: https://doi.org/10.1124/dmd.117.078873
  3. de Boussac, Hugues

    1. You have access
      Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor
      Hugues de Boussac, Claire Gondeau, Philippe Briolotti, Cédric Duret, Fridolin Treindl, Michael Römer, Jean-Michel Fabre, Astrid Herrero, Jeanne Ramos, Patrick Maurel, Markus Templin, Sabine Gerbal-Chaloin and Martine Daujat-Chavanieu
      Drug Metabolism and Disposition March 2018, 46 (3) 223-236; DOI: https://doi.org/10.1124/dmd.117.078683
  4. Dembofsky, Bruce T.

    1. Open Access
      Late-occurring and Long-circulating Metabolites of GABAAα2,3 Receptor Modulator AZD7325 Involving Metabolic Cyclization and Aromatization: Relevance to MIST Analysis and Application for Patient Compliance
      Chungang Gu, Markus Artelsmair, Charles S. Elmore, Richard J. Lewis, Patty Davis, James E. Hall, Bruce T. Dembofsky, Greg Christoph, Mark A. Smith, Marc Chapdelaine and Maria Sunzel
      Drug Metabolism and Disposition March 2018, 46 (3) 303-315; DOI: https://doi.org/10.1124/dmd.117.078873
  5. Duret, Cédric

    1. You have access
      Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor
      Hugues de Boussac, Claire Gondeau, Philippe Briolotti, Cédric Duret, Fridolin Treindl, Michael Römer, Jean-Michel Fabre, Astrid Herrero, Jeanne Ramos, Patrick Maurel, Markus Templin, Sabine Gerbal-Chaloin and Martine Daujat-Chavanieu
      Drug Metabolism and Disposition March 2018, 46 (3) 223-236; DOI: https://doi.org/10.1124/dmd.117.078683

E

  1. Ellens, Harma

    1. You have access
      Derivation of a System-Independent Ki for P-glycoprotein Mediated Digoxin Transport from System-Dependent IC50 Data
      Aqsaa Chaudhry, Git Chung, Adam Lynn, Akshata Yalvigi, Colin Brown, Harma Ellens, Michael O’Connor, Caroline Lee and Joe Bentz
      Drug Metabolism and Disposition March 2018, 46 (3) 279-290; DOI: https://doi.org/10.1124/dmd.117.075606
  2. Elmore, Charles S.

    1. Open Access
      Late-occurring and Long-circulating Metabolites of GABAAα2,3 Receptor Modulator AZD7325 Involving Metabolic Cyclization and Aromatization: Relevance to MIST Analysis and Application for Patient Compliance
      Chungang Gu, Markus Artelsmair, Charles S. Elmore, Richard J. Lewis, Patty Davis, James E. Hall, Bruce T. Dembofsky, Greg Christoph, Mark A. Smith, Marc Chapdelaine and Maria Sunzel
      Drug Metabolism and Disposition March 2018, 46 (3) 303-315; DOI: https://doi.org/10.1124/dmd.117.078873

F

  1. Fabre, Jean-Michel

    1. You have access
      Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor
      Hugues de Boussac, Claire Gondeau, Philippe Briolotti, Cédric Duret, Fridolin Treindl, Michael Römer, Jean-Michel Fabre, Astrid Herrero, Jeanne Ramos, Patrick Maurel, Markus Templin, Sabine Gerbal-Chaloin and Martine Daujat-Chavanieu
      Drug Metabolism and Disposition March 2018, 46 (3) 223-236; DOI: https://doi.org/10.1124/dmd.117.078683

G

  1. Gao, Xue-Jiao

    1. You have access
      Bacterial Outer Membrane Vesicles from Dextran Sulfate Sodium–Induced Colitis Differentially Regulate Intestinal UDP-Glucuronosyltransferase 1A1 Partially Through Toll-Like Receptor 4/Mitogen-Activated Protein Kinase/Phosphatidylinositol 3-Kinase Pathway
      Xue-Jiao Gao, Ting Li, Bin Wei, Zhi-Xiang Yan, Nan Hu, Yan-Juan Huang, Bei-Lei Han, Tai-Seng Wai, Wei Yang and Ru Yan
      Drug Metabolism and Disposition March 2018, 46 (3) 292-302; DOI: https://doi.org/10.1124/dmd.117.079046
  2. Gerbal-Chaloin, Sabine

    1. You have access
      Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor
      Hugues de Boussac, Claire Gondeau, Philippe Briolotti, Cédric Duret, Fridolin Treindl, Michael Römer, Jean-Michel Fabre, Astrid Herrero, Jeanne Ramos, Patrick Maurel, Markus Templin, Sabine Gerbal-Chaloin and Martine Daujat-Chavanieu
      Drug Metabolism and Disposition March 2018, 46 (3) 223-236; DOI: https://doi.org/10.1124/dmd.117.078683
  3. Gondeau, Claire

    1. You have access
      Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor
      Hugues de Boussac, Claire Gondeau, Philippe Briolotti, Cédric Duret, Fridolin Treindl, Michael Römer, Jean-Michel Fabre, Astrid Herrero, Jeanne Ramos, Patrick Maurel, Markus Templin, Sabine Gerbal-Chaloin and Martine Daujat-Chavanieu
      Drug Metabolism and Disposition March 2018, 46 (3) 223-236; DOI: https://doi.org/10.1124/dmd.117.078683
  4. Gong, Jiachang

    1. Open Access
      Clinical Pharmacokinetics and the Impact of Genetic Polymorphism on a CYP2C19 Substrate, BMS-823778, in Healthy Subjects
      Jiachang Gong, Lars Hansen and Lisa Iacono
      Drug Metabolism and Disposition March 2018, 46 (3) 316-325; DOI: https://doi.org/10.1124/dmd.117.078824
  5. Gu, Chungang

    1. Open Access
      Late-occurring and Long-circulating Metabolites of GABAAα2,3 Receptor Modulator AZD7325 Involving Metabolic Cyclization and Aromatization: Relevance to MIST Analysis and Application for Patient Compliance
      Chungang Gu, Markus Artelsmair, Charles S. Elmore, Richard J. Lewis, Patty Davis, James E. Hall, Bruce T. Dembofsky, Greg Christoph, Mark A. Smith, Marc Chapdelaine and Maria Sunzel
      Drug Metabolism and Disposition March 2018, 46 (3) 303-315; DOI: https://doi.org/10.1124/dmd.117.078873
  6. Guo, Lianxia

    1. You have access
      REV-ERBα Regulates CYP7A1 Through Repression of Liver Receptor Homolog-1
      Tianpeng Zhang, Mengjing Zhao, Danyi Lu, Shuai Wang, Fangjun Yu, Lianxia Guo, Shijun Wen and Baojian Wu
      Drug Metabolism and Disposition March 2018, 46 (3) 248-258; DOI: https://doi.org/10.1124/dmd.117.078105

H

  1. Hall, James E.

    1. Open Access
      Late-occurring and Long-circulating Metabolites of GABAAα2,3 Receptor Modulator AZD7325 Involving Metabolic Cyclization and Aromatization: Relevance to MIST Analysis and Application for Patient Compliance
      Chungang Gu, Markus Artelsmair, Charles S. Elmore, Richard J. Lewis, Patty Davis, James E. Hall, Bruce T. Dembofsky, Greg Christoph, Mark A. Smith, Marc Chapdelaine and Maria Sunzel
      Drug Metabolism and Disposition March 2018, 46 (3) 303-315; DOI: https://doi.org/10.1124/dmd.117.078873
  2. Hallifax, David

    1. You have access
      Importance of the Unstirred Water Layer and Hepatocyte Membrane Integrity In Vitro for Quantification of Intrinsic Metabolic Clearance
      Francesca L. Wood, J. Brian Houston and David Hallifax
      Drug Metabolism and Disposition March 2018, 46 (3) 268-278; DOI: https://doi.org/10.1124/dmd.117.078949
  3. Han, Bei-Lei

    1. You have access
      Bacterial Outer Membrane Vesicles from Dextran Sulfate Sodium–Induced Colitis Differentially Regulate Intestinal UDP-Glucuronosyltransferase 1A1 Partially Through Toll-Like Receptor 4/Mitogen-Activated Protein Kinase/Phosphatidylinositol 3-Kinase Pathway
      Xue-Jiao Gao, Ting Li, Bin Wei, Zhi-Xiang Yan, Nan Hu, Yan-Juan Huang, Bei-Lei Han, Tai-Seng Wai, Wei Yang and Ru Yan
      Drug Metabolism and Disposition March 2018, 46 (3) 292-302; DOI: https://doi.org/10.1124/dmd.117.079046
  4. Hansen, Lars

    1. Open Access
      Clinical Pharmacokinetics and the Impact of Genetic Polymorphism on a CYP2C19 Substrate, BMS-823778, in Healthy Subjects
      Jiachang Gong, Lars Hansen and Lisa Iacono
      Drug Metabolism and Disposition March 2018, 46 (3) 316-325; DOI: https://doi.org/10.1124/dmd.117.078824
  5. Hemenway, Jeffrey

    1. You have access
      Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite—Resolution for Clinical Development
      Jim Zheng, Yan Xin, Jingyu Zhang, Raju Subramanian, Bernard P. Murray, J. Andrew Whitney, Matthew R. Warr, John Ling, Lisa Moorehead, Ellen Kwan, Jeffrey Hemenway, Bill J. Smith and Jeffrey A. Silverman
      Drug Metabolism and Disposition March 2018, 46 (3) 237-247; DOI: https://doi.org/10.1124/dmd.117.078899
  6. Herrero, Astrid

    1. You have access
      Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor
      Hugues de Boussac, Claire Gondeau, Philippe Briolotti, Cédric Duret, Fridolin Treindl, Michael Römer, Jean-Michel Fabre, Astrid Herrero, Jeanne Ramos, Patrick Maurel, Markus Templin, Sabine Gerbal-Chaloin and Martine Daujat-Chavanieu
      Drug Metabolism and Disposition March 2018, 46 (3) 223-236; DOI: https://doi.org/10.1124/dmd.117.078683
  7. Houston, J. Brian

    1. You have access
      Importance of the Unstirred Water Layer and Hepatocyte Membrane Integrity In Vitro for Quantification of Intrinsic Metabolic Clearance
      Francesca L. Wood, J. Brian Houston and David Hallifax
      Drug Metabolism and Disposition March 2018, 46 (3) 268-278; DOI: https://doi.org/10.1124/dmd.117.078949
  8. Hu, Nan

    1. You have access
      Bacterial Outer Membrane Vesicles from Dextran Sulfate Sodium–Induced Colitis Differentially Regulate Intestinal UDP-Glucuronosyltransferase 1A1 Partially Through Toll-Like Receptor 4/Mitogen-Activated Protein Kinase/Phosphatidylinositol 3-Kinase Pathway
      Xue-Jiao Gao, Ting Li, Bin Wei, Zhi-Xiang Yan, Nan Hu, Yan-Juan Huang, Bei-Lei Han, Tai-Seng Wai, Wei Yang and Ru Yan
      Drug Metabolism and Disposition March 2018, 46 (3) 292-302; DOI: https://doi.org/10.1124/dmd.117.079046
  9. Huang, Yan-Juan

    1. You have access
      Bacterial Outer Membrane Vesicles from Dextran Sulfate Sodium–Induced Colitis Differentially Regulate Intestinal UDP-Glucuronosyltransferase 1A1 Partially Through Toll-Like Receptor 4/Mitogen-Activated Protein Kinase/Phosphatidylinositol 3-Kinase Pathway
      Xue-Jiao Gao, Ting Li, Bin Wei, Zhi-Xiang Yan, Nan Hu, Yan-Juan Huang, Bei-Lei Han, Tai-Seng Wai, Wei Yang and Ru Yan
      Drug Metabolism and Disposition March 2018, 46 (3) 292-302; DOI: https://doi.org/10.1124/dmd.117.079046

I

  1. Iacono, Lisa

    1. Open Access
      Clinical Pharmacokinetics and the Impact of Genetic Polymorphism on a CYP2C19 Substrate, BMS-823778, in Healthy Subjects
      Jiachang Gong, Lars Hansen and Lisa Iacono
      Drug Metabolism and Disposition March 2018, 46 (3) 316-325; DOI: https://doi.org/10.1124/dmd.117.078824
  2. Ishiguro, Naoki

    1. You have access
      Impact of Breast Cancer Resistance Protein Expression on the In Vitro Efficacy of Anticancer Drugs in Pancreatic Cancer Cell Lines
      Ikumi Washio, Takeo Nakanishi, Naoki Ishiguro, Norio Yamamura and Ikumi Tamai
      Drug Metabolism and Disposition March 2018, 46 (3) 214-222; DOI: https://doi.org/10.1124/dmd.117.078402
  3. Iwakado, Shouko

    1. You have access
      The Phenomenon of Albumin-Mediated Hepatic Uptake of Organic Anion Transport Polypeptide Substrates: Prediction of the In Vivo Uptake Clearance from the In Vitro Uptake by Isolated Hepatocytes Using a Facilitated-Dissociation Model
      Seiji Miyauchi, Masayuki Masuda, Soo-Jin Kim, Yuudai Tanaka, Kyeong-Ryoon Lee, Shouko Iwakado, Momoko Nemoto, Shotaro Sasaki, Kazumi Shimono, Yoshio Tanaka and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2018, 46 (3) 259-267; DOI: https://doi.org/10.1124/dmd.117.077115

K

  1. Kim, Soo-Jin

    1. You have access
      The Phenomenon of Albumin-Mediated Hepatic Uptake of Organic Anion Transport Polypeptide Substrates: Prediction of the In Vivo Uptake Clearance from the In Vitro Uptake by Isolated Hepatocytes Using a Facilitated-Dissociation Model
      Seiji Miyauchi, Masayuki Masuda, Soo-Jin Kim, Yuudai Tanaka, Kyeong-Ryoon Lee, Shouko Iwakado, Momoko Nemoto, Shotaro Sasaki, Kazumi Shimono, Yoshio Tanaka and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2018, 46 (3) 259-267; DOI: https://doi.org/10.1124/dmd.117.077115
  2. Kondo, Takahiro

    1. You have access
      Mechanism for Covalent Binding of MLN3126, an Oral Chemokine C-C Motif Receptor 9 Antagonist, to Serum Albumins
      Naohiro Narita, Akio Morohashi, Kimio Tohyama, Toshiyuki Takeuchi, Yoshihiko Tagawa, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition March 2018, 46 (3) 204-213; DOI: https://doi.org/10.1124/dmd.117.078782
  3. Kwan, Ellen

    1. You have access
      Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite—Resolution for Clinical Development
      Jim Zheng, Yan Xin, Jingyu Zhang, Raju Subramanian, Bernard P. Murray, J. Andrew Whitney, Matthew R. Warr, John Ling, Lisa Moorehead, Ellen Kwan, Jeffrey Hemenway, Bill J. Smith and Jeffrey A. Silverman
      Drug Metabolism and Disposition March 2018, 46 (3) 237-247; DOI: https://doi.org/10.1124/dmd.117.078899

L

  1. Lee, Caroline

    1. You have access
      Derivation of a System-Independent Ki for P-glycoprotein Mediated Digoxin Transport from System-Dependent IC50 Data
      Aqsaa Chaudhry, Git Chung, Adam Lynn, Akshata Yalvigi, Colin Brown, Harma Ellens, Michael O’Connor, Caroline Lee and Joe Bentz
      Drug Metabolism and Disposition March 2018, 46 (3) 279-290; DOI: https://doi.org/10.1124/dmd.117.075606
  2. Lee, Kyeong-Ryoon

    1. You have access
      The Phenomenon of Albumin-Mediated Hepatic Uptake of Organic Anion Transport Polypeptide Substrates: Prediction of the In Vivo Uptake Clearance from the In Vitro Uptake by Isolated Hepatocytes Using a Facilitated-Dissociation Model
      Seiji Miyauchi, Masayuki Masuda, Soo-Jin Kim, Yuudai Tanaka, Kyeong-Ryoon Lee, Shouko Iwakado, Momoko Nemoto, Shotaro Sasaki, Kazumi Shimono, Yoshio Tanaka and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2018, 46 (3) 259-267; DOI: https://doi.org/10.1124/dmd.117.077115
  3. Lewis, Richard J.

    1. Open Access
      Late-occurring and Long-circulating Metabolites of GABAAα2,3 Receptor Modulator AZD7325 Involving Metabolic Cyclization and Aromatization: Relevance to MIST Analysis and Application for Patient Compliance
      Chungang Gu, Markus Artelsmair, Charles S. Elmore, Richard J. Lewis, Patty Davis, James E. Hall, Bruce T. Dembofsky, Greg Christoph, Mark A. Smith, Marc Chapdelaine and Maria Sunzel
      Drug Metabolism and Disposition March 2018, 46 (3) 303-315; DOI: https://doi.org/10.1124/dmd.117.078873
  4. Li, Ting

    1. You have access
      Bacterial Outer Membrane Vesicles from Dextran Sulfate Sodium–Induced Colitis Differentially Regulate Intestinal UDP-Glucuronosyltransferase 1A1 Partially Through Toll-Like Receptor 4/Mitogen-Activated Protein Kinase/Phosphatidylinositol 3-Kinase Pathway
      Xue-Jiao Gao, Ting Li, Bin Wei, Zhi-Xiang Yan, Nan Hu, Yan-Juan Huang, Bei-Lei Han, Tai-Seng Wai, Wei Yang and Ru Yan
      Drug Metabolism and Disposition March 2018, 46 (3) 292-302; DOI: https://doi.org/10.1124/dmd.117.079046
  5. Ling, John

    1. You have access
      Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite—Resolution for Clinical Development
      Jim Zheng, Yan Xin, Jingyu Zhang, Raju Subramanian, Bernard P. Murray, J. Andrew Whitney, Matthew R. Warr, John Ling, Lisa Moorehead, Ellen Kwan, Jeffrey Hemenway, Bill J. Smith and Jeffrey A. Silverman
      Drug Metabolism and Disposition March 2018, 46 (3) 237-247; DOI: https://doi.org/10.1124/dmd.117.078899
  6. Lu, Danyi

    1. You have access
      REV-ERBα Regulates CYP7A1 Through Repression of Liver Receptor Homolog-1
      Tianpeng Zhang, Mengjing Zhao, Danyi Lu, Shuai Wang, Fangjun Yu, Lianxia Guo, Shijun Wen and Baojian Wu
      Drug Metabolism and Disposition March 2018, 46 (3) 248-258; DOI: https://doi.org/10.1124/dmd.117.078105
  7. Lynn, Adam

    1. You have access
      Derivation of a System-Independent Ki for P-glycoprotein Mediated Digoxin Transport from System-Dependent IC50 Data
      Aqsaa Chaudhry, Git Chung, Adam Lynn, Akshata Yalvigi, Colin Brown, Harma Ellens, Michael O’Connor, Caroline Lee and Joe Bentz
      Drug Metabolism and Disposition March 2018, 46 (3) 279-290; DOI: https://doi.org/10.1124/dmd.117.075606

M

  1. Masuda, Masayuki

    1. You have access
      The Phenomenon of Albumin-Mediated Hepatic Uptake of Organic Anion Transport Polypeptide Substrates: Prediction of the In Vivo Uptake Clearance from the In Vitro Uptake by Isolated Hepatocytes Using a Facilitated-Dissociation Model
      Seiji Miyauchi, Masayuki Masuda, Soo-Jin Kim, Yuudai Tanaka, Kyeong-Ryoon Lee, Shouko Iwakado, Momoko Nemoto, Shotaro Sasaki, Kazumi Shimono, Yoshio Tanaka and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2018, 46 (3) 259-267; DOI: https://doi.org/10.1124/dmd.117.077115
  2. Maurel, Patrick

    1. You have access
      Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor
      Hugues de Boussac, Claire Gondeau, Philippe Briolotti, Cédric Duret, Fridolin Treindl, Michael Römer, Jean-Michel Fabre, Astrid Herrero, Jeanne Ramos, Patrick Maurel, Markus Templin, Sabine Gerbal-Chaloin and Martine Daujat-Chavanieu
      Drug Metabolism and Disposition March 2018, 46 (3) 223-236; DOI: https://doi.org/10.1124/dmd.117.078683
  3. Miyauchi, Seiji

    1. You have access
      The Phenomenon of Albumin-Mediated Hepatic Uptake of Organic Anion Transport Polypeptide Substrates: Prediction of the In Vivo Uptake Clearance from the In Vitro Uptake by Isolated Hepatocytes Using a Facilitated-Dissociation Model
      Seiji Miyauchi, Masayuki Masuda, Soo-Jin Kim, Yuudai Tanaka, Kyeong-Ryoon Lee, Shouko Iwakado, Momoko Nemoto, Shotaro Sasaki, Kazumi Shimono, Yoshio Tanaka and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2018, 46 (3) 259-267; DOI: https://doi.org/10.1124/dmd.117.077115
  4. Moorehead, Lisa

    1. You have access
      Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite—Resolution for Clinical Development
      Jim Zheng, Yan Xin, Jingyu Zhang, Raju Subramanian, Bernard P. Murray, J. Andrew Whitney, Matthew R. Warr, John Ling, Lisa Moorehead, Ellen Kwan, Jeffrey Hemenway, Bill J. Smith and Jeffrey A. Silverman
      Drug Metabolism and Disposition March 2018, 46 (3) 237-247; DOI: https://doi.org/10.1124/dmd.117.078899
  5. Morohashi, Akio

    1. You have access
      Mechanism for Covalent Binding of MLN3126, an Oral Chemokine C-C Motif Receptor 9 Antagonist, to Serum Albumins
      Naohiro Narita, Akio Morohashi, Kimio Tohyama, Toshiyuki Takeuchi, Yoshihiko Tagawa, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition March 2018, 46 (3) 204-213; DOI: https://doi.org/10.1124/dmd.117.078782
  6. Murray, Bernard P.

    1. You have access
      Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite—Resolution for Clinical Development
      Jim Zheng, Yan Xin, Jingyu Zhang, Raju Subramanian, Bernard P. Murray, J. Andrew Whitney, Matthew R. Warr, John Ling, Lisa Moorehead, Ellen Kwan, Jeffrey Hemenway, Bill J. Smith and Jeffrey A. Silverman
      Drug Metabolism and Disposition March 2018, 46 (3) 237-247; DOI: https://doi.org/10.1124/dmd.117.078899

N

  1. Nakanishi, Takeo

    1. You have access
      Impact of Breast Cancer Resistance Protein Expression on the In Vitro Efficacy of Anticancer Drugs in Pancreatic Cancer Cell Lines
      Ikumi Washio, Takeo Nakanishi, Naoki Ishiguro, Norio Yamamura and Ikumi Tamai
      Drug Metabolism and Disposition March 2018, 46 (3) 214-222; DOI: https://doi.org/10.1124/dmd.117.078402
  2. Narita, Naohiro

    1. You have access
      Mechanism for Covalent Binding of MLN3126, an Oral Chemokine C-C Motif Receptor 9 Antagonist, to Serum Albumins
      Naohiro Narita, Akio Morohashi, Kimio Tohyama, Toshiyuki Takeuchi, Yoshihiko Tagawa, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition March 2018, 46 (3) 204-213; DOI: https://doi.org/10.1124/dmd.117.078782
  3. Nemoto, Momoko

    1. You have access
      The Phenomenon of Albumin-Mediated Hepatic Uptake of Organic Anion Transport Polypeptide Substrates: Prediction of the In Vivo Uptake Clearance from the In Vitro Uptake by Isolated Hepatocytes Using a Facilitated-Dissociation Model
      Seiji Miyauchi, Masayuki Masuda, Soo-Jin Kim, Yuudai Tanaka, Kyeong-Ryoon Lee, Shouko Iwakado, Momoko Nemoto, Shotaro Sasaki, Kazumi Shimono, Yoshio Tanaka and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2018, 46 (3) 259-267; DOI: https://doi.org/10.1124/dmd.117.077115

O

  1. O’Connor, Michael

    1. You have access
      Derivation of a System-Independent Ki for P-glycoprotein Mediated Digoxin Transport from System-Dependent IC50 Data
      Aqsaa Chaudhry, Git Chung, Adam Lynn, Akshata Yalvigi, Colin Brown, Harma Ellens, Michael O’Connor, Caroline Lee and Joe Bentz
      Drug Metabolism and Disposition March 2018, 46 (3) 279-290; DOI: https://doi.org/10.1124/dmd.117.075606

R

  1. Ramos, Jeanne

    1. You have access
      Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor
      Hugues de Boussac, Claire Gondeau, Philippe Briolotti, Cédric Duret, Fridolin Treindl, Michael Römer, Jean-Michel Fabre, Astrid Herrero, Jeanne Ramos, Patrick Maurel, Markus Templin, Sabine Gerbal-Chaloin and Martine Daujat-Chavanieu
      Drug Metabolism and Disposition March 2018, 46 (3) 223-236; DOI: https://doi.org/10.1124/dmd.117.078683
  2. Reed, James R.

    1. You have access
      Characterization of Interactions Among CYP1A2, CYP2B4, and NADPH-cytochrome P450 Reductase: Identification of Specific Protein Complexes
      J. Patrick Connick, James R. Reed and Wayne L. Backes
      Drug Metabolism and Disposition March 2018, 46 (3) 197-203; DOI: https://doi.org/10.1124/dmd.117.078642
  3. Römer, Michael

    1. You have access
      Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor
      Hugues de Boussac, Claire Gondeau, Philippe Briolotti, Cédric Duret, Fridolin Treindl, Michael Römer, Jean-Michel Fabre, Astrid Herrero, Jeanne Ramos, Patrick Maurel, Markus Templin, Sabine Gerbal-Chaloin and Martine Daujat-Chavanieu
      Drug Metabolism and Disposition March 2018, 46 (3) 223-236; DOI: https://doi.org/10.1124/dmd.117.078683

S

  1. Sasaki, Shotaro

    1. You have access
      The Phenomenon of Albumin-Mediated Hepatic Uptake of Organic Anion Transport Polypeptide Substrates: Prediction of the In Vivo Uptake Clearance from the In Vitro Uptake by Isolated Hepatocytes Using a Facilitated-Dissociation Model
      Seiji Miyauchi, Masayuki Masuda, Soo-Jin Kim, Yuudai Tanaka, Kyeong-Ryoon Lee, Shouko Iwakado, Momoko Nemoto, Shotaro Sasaki, Kazumi Shimono, Yoshio Tanaka and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2018, 46 (3) 259-267; DOI: https://doi.org/10.1124/dmd.117.077115
  2. Shimono, Kazumi

    1. You have access
      The Phenomenon of Albumin-Mediated Hepatic Uptake of Organic Anion Transport Polypeptide Substrates: Prediction of the In Vivo Uptake Clearance from the In Vitro Uptake by Isolated Hepatocytes Using a Facilitated-Dissociation Model
      Seiji Miyauchi, Masayuki Masuda, Soo-Jin Kim, Yuudai Tanaka, Kyeong-Ryoon Lee, Shouko Iwakado, Momoko Nemoto, Shotaro Sasaki, Kazumi Shimono, Yoshio Tanaka and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2018, 46 (3) 259-267; DOI: https://doi.org/10.1124/dmd.117.077115
  3. Silverman, Jeffrey A.

    1. You have access
      Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite—Resolution for Clinical Development
      Jim Zheng, Yan Xin, Jingyu Zhang, Raju Subramanian, Bernard P. Murray, J. Andrew Whitney, Matthew R. Warr, John Ling, Lisa Moorehead, Ellen Kwan, Jeffrey Hemenway, Bill J. Smith and Jeffrey A. Silverman
      Drug Metabolism and Disposition March 2018, 46 (3) 237-247; DOI: https://doi.org/10.1124/dmd.117.078899
  4. Smith, Bill J.

    1. You have access
      Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite—Resolution for Clinical Development
      Jim Zheng, Yan Xin, Jingyu Zhang, Raju Subramanian, Bernard P. Murray, J. Andrew Whitney, Matthew R. Warr, John Ling, Lisa Moorehead, Ellen Kwan, Jeffrey Hemenway, Bill J. Smith and Jeffrey A. Silverman
      Drug Metabolism and Disposition March 2018, 46 (3) 237-247; DOI: https://doi.org/10.1124/dmd.117.078899
  5. Smith, Mark A.

    1. Open Access
      Late-occurring and Long-circulating Metabolites of GABAAα2,3 Receptor Modulator AZD7325 Involving Metabolic Cyclization and Aromatization: Relevance to MIST Analysis and Application for Patient Compliance
      Chungang Gu, Markus Artelsmair, Charles S. Elmore, Richard J. Lewis, Patty Davis, James E. Hall, Bruce T. Dembofsky, Greg Christoph, Mark A. Smith, Marc Chapdelaine and Maria Sunzel
      Drug Metabolism and Disposition March 2018, 46 (3) 303-315; DOI: https://doi.org/10.1124/dmd.117.078873
  6. Subramanian, Raju

    1. You have access
      Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite—Resolution for Clinical Development
      Jim Zheng, Yan Xin, Jingyu Zhang, Raju Subramanian, Bernard P. Murray, J. Andrew Whitney, Matthew R. Warr, John Ling, Lisa Moorehead, Ellen Kwan, Jeffrey Hemenway, Bill J. Smith and Jeffrey A. Silverman
      Drug Metabolism and Disposition March 2018, 46 (3) 237-247; DOI: https://doi.org/10.1124/dmd.117.078899
  7. Sugiyama, Yuichi

    1. You have access
      The Phenomenon of Albumin-Mediated Hepatic Uptake of Organic Anion Transport Polypeptide Substrates: Prediction of the In Vivo Uptake Clearance from the In Vitro Uptake by Isolated Hepatocytes Using a Facilitated-Dissociation Model
      Seiji Miyauchi, Masayuki Masuda, Soo-Jin Kim, Yuudai Tanaka, Kyeong-Ryoon Lee, Shouko Iwakado, Momoko Nemoto, Shotaro Sasaki, Kazumi Shimono, Yoshio Tanaka and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2018, 46 (3) 259-267; DOI: https://doi.org/10.1124/dmd.117.077115
  8. Sunzel, Maria

    1. Open Access
      Late-occurring and Long-circulating Metabolites of GABAAα2,3 Receptor Modulator AZD7325 Involving Metabolic Cyclization and Aromatization: Relevance to MIST Analysis and Application for Patient Compliance
      Chungang Gu, Markus Artelsmair, Charles S. Elmore, Richard J. Lewis, Patty Davis, James E. Hall, Bruce T. Dembofsky, Greg Christoph, Mark A. Smith, Marc Chapdelaine and Maria Sunzel
      Drug Metabolism and Disposition March 2018, 46 (3) 303-315; DOI: https://doi.org/10.1124/dmd.117.078873

T

  1. Tagawa, Yoshihiko

    1. You have access
      Mechanism for Covalent Binding of MLN3126, an Oral Chemokine C-C Motif Receptor 9 Antagonist, to Serum Albumins
      Naohiro Narita, Akio Morohashi, Kimio Tohyama, Toshiyuki Takeuchi, Yoshihiko Tagawa, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition March 2018, 46 (3) 204-213; DOI: https://doi.org/10.1124/dmd.117.078782
  2. Takeuchi, Toshiyuki

    1. You have access
      Mechanism for Covalent Binding of MLN3126, an Oral Chemokine C-C Motif Receptor 9 Antagonist, to Serum Albumins
      Naohiro Narita, Akio Morohashi, Kimio Tohyama, Toshiyuki Takeuchi, Yoshihiko Tagawa, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition March 2018, 46 (3) 204-213; DOI: https://doi.org/10.1124/dmd.117.078782
  3. Tamai, Ikumi

    1. You have access
      Impact of Breast Cancer Resistance Protein Expression on the In Vitro Efficacy of Anticancer Drugs in Pancreatic Cancer Cell Lines
      Ikumi Washio, Takeo Nakanishi, Naoki Ishiguro, Norio Yamamura and Ikumi Tamai
      Drug Metabolism and Disposition March 2018, 46 (3) 214-222; DOI: https://doi.org/10.1124/dmd.117.078402
  4. Tanaka, Yoshio

    1. You have access
      The Phenomenon of Albumin-Mediated Hepatic Uptake of Organic Anion Transport Polypeptide Substrates: Prediction of the In Vivo Uptake Clearance from the In Vitro Uptake by Isolated Hepatocytes Using a Facilitated-Dissociation Model
      Seiji Miyauchi, Masayuki Masuda, Soo-Jin Kim, Yuudai Tanaka, Kyeong-Ryoon Lee, Shouko Iwakado, Momoko Nemoto, Shotaro Sasaki, Kazumi Shimono, Yoshio Tanaka and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2018, 46 (3) 259-267; DOI: https://doi.org/10.1124/dmd.117.077115
  5. Tanaka, Yuudai

    1. You have access
      The Phenomenon of Albumin-Mediated Hepatic Uptake of Organic Anion Transport Polypeptide Substrates: Prediction of the In Vivo Uptake Clearance from the In Vitro Uptake by Isolated Hepatocytes Using a Facilitated-Dissociation Model
      Seiji Miyauchi, Masayuki Masuda, Soo-Jin Kim, Yuudai Tanaka, Kyeong-Ryoon Lee, Shouko Iwakado, Momoko Nemoto, Shotaro Sasaki, Kazumi Shimono, Yoshio Tanaka and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2018, 46 (3) 259-267; DOI: https://doi.org/10.1124/dmd.117.077115
  6. Templin, Markus

    1. You have access
      Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor
      Hugues de Boussac, Claire Gondeau, Philippe Briolotti, Cédric Duret, Fridolin Treindl, Michael Römer, Jean-Michel Fabre, Astrid Herrero, Jeanne Ramos, Patrick Maurel, Markus Templin, Sabine Gerbal-Chaloin and Martine Daujat-Chavanieu
      Drug Metabolism and Disposition March 2018, 46 (3) 223-236; DOI: https://doi.org/10.1124/dmd.117.078683
  7. Tohyama, Kimio

    1. You have access
      Mechanism for Covalent Binding of MLN3126, an Oral Chemokine C-C Motif Receptor 9 Antagonist, to Serum Albumins
      Naohiro Narita, Akio Morohashi, Kimio Tohyama, Toshiyuki Takeuchi, Yoshihiko Tagawa, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition March 2018, 46 (3) 204-213; DOI: https://doi.org/10.1124/dmd.117.078782
  8. Treindl, Fridolin

    1. You have access
      Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor
      Hugues de Boussac, Claire Gondeau, Philippe Briolotti, Cédric Duret, Fridolin Treindl, Michael Römer, Jean-Michel Fabre, Astrid Herrero, Jeanne Ramos, Patrick Maurel, Markus Templin, Sabine Gerbal-Chaloin and Martine Daujat-Chavanieu
      Drug Metabolism and Disposition March 2018, 46 (3) 223-236; DOI: https://doi.org/10.1124/dmd.117.078683

W

  1. Wai, Tai-Seng

    1. You have access
      Bacterial Outer Membrane Vesicles from Dextran Sulfate Sodium–Induced Colitis Differentially Regulate Intestinal UDP-Glucuronosyltransferase 1A1 Partially Through Toll-Like Receptor 4/Mitogen-Activated Protein Kinase/Phosphatidylinositol 3-Kinase Pathway
      Xue-Jiao Gao, Ting Li, Bin Wei, Zhi-Xiang Yan, Nan Hu, Yan-Juan Huang, Bei-Lei Han, Tai-Seng Wai, Wei Yang and Ru Yan
      Drug Metabolism and Disposition March 2018, 46 (3) 292-302; DOI: https://doi.org/10.1124/dmd.117.079046
  2. Wang, Shuai

    1. You have access
      REV-ERBα Regulates CYP7A1 Through Repression of Liver Receptor Homolog-1
      Tianpeng Zhang, Mengjing Zhao, Danyi Lu, Shuai Wang, Fangjun Yu, Lianxia Guo, Shijun Wen and Baojian Wu
      Drug Metabolism and Disposition March 2018, 46 (3) 248-258; DOI: https://doi.org/10.1124/dmd.117.078105
  3. Warr, Matthew R.

    1. You have access
      Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite—Resolution for Clinical Development
      Jim Zheng, Yan Xin, Jingyu Zhang, Raju Subramanian, Bernard P. Murray, J. Andrew Whitney, Matthew R. Warr, John Ling, Lisa Moorehead, Ellen Kwan, Jeffrey Hemenway, Bill J. Smith and Jeffrey A. Silverman
      Drug Metabolism and Disposition March 2018, 46 (3) 237-247; DOI: https://doi.org/10.1124/dmd.117.078899
  4. Washio, Ikumi

    1. You have access
      Impact of Breast Cancer Resistance Protein Expression on the In Vitro Efficacy of Anticancer Drugs in Pancreatic Cancer Cell Lines
      Ikumi Washio, Takeo Nakanishi, Naoki Ishiguro, Norio Yamamura and Ikumi Tamai
      Drug Metabolism and Disposition March 2018, 46 (3) 214-222; DOI: https://doi.org/10.1124/dmd.117.078402
  5. Wei, Bin

    1. You have access
      Bacterial Outer Membrane Vesicles from Dextran Sulfate Sodium–Induced Colitis Differentially Regulate Intestinal UDP-Glucuronosyltransferase 1A1 Partially Through Toll-Like Receptor 4/Mitogen-Activated Protein Kinase/Phosphatidylinositol 3-Kinase Pathway
      Xue-Jiao Gao, Ting Li, Bin Wei, Zhi-Xiang Yan, Nan Hu, Yan-Juan Huang, Bei-Lei Han, Tai-Seng Wai, Wei Yang and Ru Yan
      Drug Metabolism and Disposition March 2018, 46 (3) 292-302; DOI: https://doi.org/10.1124/dmd.117.079046
  6. Wen, Shijun

    1. You have access
      REV-ERBα Regulates CYP7A1 Through Repression of Liver Receptor Homolog-1
      Tianpeng Zhang, Mengjing Zhao, Danyi Lu, Shuai Wang, Fangjun Yu, Lianxia Guo, Shijun Wen and Baojian Wu
      Drug Metabolism and Disposition March 2018, 46 (3) 248-258; DOI: https://doi.org/10.1124/dmd.117.078105
  7. Whitney, J. Andrew

    1. You have access
      Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite—Resolution for Clinical Development
      Jim Zheng, Yan Xin, Jingyu Zhang, Raju Subramanian, Bernard P. Murray, J. Andrew Whitney, Matthew R. Warr, John Ling, Lisa Moorehead, Ellen Kwan, Jeffrey Hemenway, Bill J. Smith and Jeffrey A. Silverman
      Drug Metabolism and Disposition March 2018, 46 (3) 237-247; DOI: https://doi.org/10.1124/dmd.117.078899
  8. Wood, Francesca L.

    1. You have access
      Importance of the Unstirred Water Layer and Hepatocyte Membrane Integrity In Vitro for Quantification of Intrinsic Metabolic Clearance
      Francesca L. Wood, J. Brian Houston and David Hallifax
      Drug Metabolism and Disposition March 2018, 46 (3) 268-278; DOI: https://doi.org/10.1124/dmd.117.078949
  9. Wu, Baojian

    1. You have access
      REV-ERBα Regulates CYP7A1 Through Repression of Liver Receptor Homolog-1
      Tianpeng Zhang, Mengjing Zhao, Danyi Lu, Shuai Wang, Fangjun Yu, Lianxia Guo, Shijun Wen and Baojian Wu
      Drug Metabolism and Disposition March 2018, 46 (3) 248-258; DOI: https://doi.org/10.1124/dmd.117.078105

X

  1. Xin, Yan

    1. You have access
      Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite—Resolution for Clinical Development
      Jim Zheng, Yan Xin, Jingyu Zhang, Raju Subramanian, Bernard P. Murray, J. Andrew Whitney, Matthew R. Warr, John Ling, Lisa Moorehead, Ellen Kwan, Jeffrey Hemenway, Bill J. Smith and Jeffrey A. Silverman
      Drug Metabolism and Disposition March 2018, 46 (3) 237-247; DOI: https://doi.org/10.1124/dmd.117.078899

Y

  1. Yalvigi, Akshata

    1. You have access
      Derivation of a System-Independent Ki for P-glycoprotein Mediated Digoxin Transport from System-Dependent IC50 Data
      Aqsaa Chaudhry, Git Chung, Adam Lynn, Akshata Yalvigi, Colin Brown, Harma Ellens, Michael O’Connor, Caroline Lee and Joe Bentz
      Drug Metabolism and Disposition March 2018, 46 (3) 279-290; DOI: https://doi.org/10.1124/dmd.117.075606
  2. Yamamura, Norio

    1. You have access
      Impact of Breast Cancer Resistance Protein Expression on the In Vitro Efficacy of Anticancer Drugs in Pancreatic Cancer Cell Lines
      Ikumi Washio, Takeo Nakanishi, Naoki Ishiguro, Norio Yamamura and Ikumi Tamai
      Drug Metabolism and Disposition March 2018, 46 (3) 214-222; DOI: https://doi.org/10.1124/dmd.117.078402
  3. Yan, Ru

    1. You have access
      Bacterial Outer Membrane Vesicles from Dextran Sulfate Sodium–Induced Colitis Differentially Regulate Intestinal UDP-Glucuronosyltransferase 1A1 Partially Through Toll-Like Receptor 4/Mitogen-Activated Protein Kinase/Phosphatidylinositol 3-Kinase Pathway
      Xue-Jiao Gao, Ting Li, Bin Wei, Zhi-Xiang Yan, Nan Hu, Yan-Juan Huang, Bei-Lei Han, Tai-Seng Wai, Wei Yang and Ru Yan
      Drug Metabolism and Disposition March 2018, 46 (3) 292-302; DOI: https://doi.org/10.1124/dmd.117.079046
  4. Yan, Zhi-Xiang

    1. You have access
      Bacterial Outer Membrane Vesicles from Dextran Sulfate Sodium–Induced Colitis Differentially Regulate Intestinal UDP-Glucuronosyltransferase 1A1 Partially Through Toll-Like Receptor 4/Mitogen-Activated Protein Kinase/Phosphatidylinositol 3-Kinase Pathway
      Xue-Jiao Gao, Ting Li, Bin Wei, Zhi-Xiang Yan, Nan Hu, Yan-Juan Huang, Bei-Lei Han, Tai-Seng Wai, Wei Yang and Ru Yan
      Drug Metabolism and Disposition March 2018, 46 (3) 292-302; DOI: https://doi.org/10.1124/dmd.117.079046
  5. Yang, Wei

    1. You have access
      Bacterial Outer Membrane Vesicles from Dextran Sulfate Sodium–Induced Colitis Differentially Regulate Intestinal UDP-Glucuronosyltransferase 1A1 Partially Through Toll-Like Receptor 4/Mitogen-Activated Protein Kinase/Phosphatidylinositol 3-Kinase Pathway
      Xue-Jiao Gao, Ting Li, Bin Wei, Zhi-Xiang Yan, Nan Hu, Yan-Juan Huang, Bei-Lei Han, Tai-Seng Wai, Wei Yang and Ru Yan
      Drug Metabolism and Disposition March 2018, 46 (3) 292-302; DOI: https://doi.org/10.1124/dmd.117.079046
  6. Yu, Fangjun

    1. You have access
      REV-ERBα Regulates CYP7A1 Through Repression of Liver Receptor Homolog-1
      Tianpeng Zhang, Mengjing Zhao, Danyi Lu, Shuai Wang, Fangjun Yu, Lianxia Guo, Shijun Wen and Baojian Wu
      Drug Metabolism and Disposition March 2018, 46 (3) 248-258; DOI: https://doi.org/10.1124/dmd.117.078105

Z

  1. Zhang, Jingyu

    1. You have access
      Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite—Resolution for Clinical Development
      Jim Zheng, Yan Xin, Jingyu Zhang, Raju Subramanian, Bernard P. Murray, J. Andrew Whitney, Matthew R. Warr, John Ling, Lisa Moorehead, Ellen Kwan, Jeffrey Hemenway, Bill J. Smith and Jeffrey A. Silverman
      Drug Metabolism and Disposition March 2018, 46 (3) 237-247; DOI: https://doi.org/10.1124/dmd.117.078899
  2. Zhang, Tianpeng

    1. You have access
      REV-ERBα Regulates CYP7A1 Through Repression of Liver Receptor Homolog-1
      Tianpeng Zhang, Mengjing Zhao, Danyi Lu, Shuai Wang, Fangjun Yu, Lianxia Guo, Shijun Wen and Baojian Wu
      Drug Metabolism and Disposition March 2018, 46 (3) 248-258; DOI: https://doi.org/10.1124/dmd.117.078105
  3. Zhao, Mengjing

    1. You have access
      REV-ERBα Regulates CYP7A1 Through Repression of Liver Receptor Homolog-1
      Tianpeng Zhang, Mengjing Zhao, Danyi Lu, Shuai Wang, Fangjun Yu, Lianxia Guo, Shijun Wen and Baojian Wu
      Drug Metabolism and Disposition March 2018, 46 (3) 248-258; DOI: https://doi.org/10.1124/dmd.117.078105
  4. Zheng, Jim

    1. You have access
      Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite—Resolution for Clinical Development
      Jim Zheng, Yan Xin, Jingyu Zhang, Raju Subramanian, Bernard P. Murray, J. Andrew Whitney, Matthew R. Warr, John Ling, Lisa Moorehead, Ellen Kwan, Jeffrey Hemenway, Bill J. Smith and Jeffrey A. Silverman
      Drug Metabolism and Disposition March 2018, 46 (3) 237-247; DOI: https://doi.org/10.1124/dmd.117.078899
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Drug Metabolism and Disposition: 46 (3)
Drug Metabolism and Disposition
Vol. 46, Issue 3
1 Mar 2018
  • Table of Contents
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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  • Journal of Pharmacology and Experimental Therapeutics
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ISSN 1521-009X (Online)

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