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Drug Metabolism & Disposition

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Index by author

May 01, 2018; Volume 46,Issue 5
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Abe, Koji

    1. You have access
      Curcumin as an In Vivo Selective Intestinal Breast Cancer Resistance Protein Inhibitor in Cynomolgus Monkeys
      Tsuyoshi Karibe, Tomoki Imaoka, Koji Abe and Osamu Ando
      Drug Metabolism and Disposition May 2018, 46 (5) 667-679; DOI: https://doi.org/10.1124/dmd.117.078931
  2. Ahituv, Nadav

    1. You have access
      Rare Variants in the ABCG2 Promoter Modulate In Vivo Activity
      Rachel J. Eclov, Mee J. Kim, Robin Smith, Nadav Ahituv and Deanna L. Kroetz
      Drug Metabolism and Disposition May 2018, 46 (5) 636-642; DOI: https://doi.org/10.1124/dmd.117.079541
  3. Al-Judaibi, Bandar

    1. You have access
      Apixaban and Rosuvas­­tatin Pharmacokinetics in Nonalcoholic Fatty Liver Disease
      Rommel G. Tirona, Zahra Kassam, Ruth Strapp, Mala Ramu, Catherine Zhu, Melissa Liu, Ute I. Schwarz, Richard B. Kim, Bandar Al-Judaibi and Melanie D. Beaton
      Drug Metabolism and Disposition May 2018, 46 (5) 485-492; DOI: https://doi.org/10.1124/dmd.117.079624
  4. Aleksunes, Lauren M.

    1. Interindividual Regulation of the Breast Cancer Resistance Protein/<em>ABCG2</em> Transporter in Term Human Placentas
      You have access
      Interindividual Regulation of the Breast Cancer Resistance Protein/ABCG2 Transporter in Term Human Placentas
      Kristin M. Bircsak, Jamie E. Moscovitz, Xia Wen, Faith Archer, Poi Yu Sofia Yuen, Moiz Mohammed, Naureen Memon, Barry I. Weinberger, Laura M. Saba, Anna M. Vetrano and Lauren M. Aleksunes
      Drug Metabolism and Disposition May 2018, 46 (5) 619-627; DOI: https://doi.org/10.1124/dmd.117.079228
  5. Allain, Eric P.

    1. Post-transcriptional Regulation of UGT2B10 Hepatic Expression and Activity by Alternative Splicing
      You have access
      Post-transcriptional Regulation of UGT2B10 Hepatic Expression and Activity by Alternative Splicing
      Adrien Labriet, Eric P. Allain, Michèle Rouleau, Yannick Audet-Delage, Lyne Villeneuve and Chantal Guillemette
      Drug Metabolism and Disposition May 2018, 46 (5) 514-524; DOI: https://doi.org/10.1124/dmd.117.079921
  6. Ando, Osamu

    1. You have access
      Curcumin as an In Vivo Selective Intestinal Breast Cancer Resistance Protein Inhibitor in Cynomolgus Monkeys
      Tsuyoshi Karibe, Tomoki Imaoka, Koji Abe and Osamu Ando
      Drug Metabolism and Disposition May 2018, 46 (5) 667-679; DOI: https://doi.org/10.1124/dmd.117.078931
  7. Annaert, Pieter

    1. You have access
      MRP2 Inhibition by HIV Protease Inhibitors in Rat and Human Hepatocytes: A Quantitative Confocal Microscopy Study
      Nico Holmstock, Marlies Oorts, Jan Snoeys and Pieter Annaert
      Drug Metabolism and Disposition May 2018, 46 (5) 697-703; DOI: https://doi.org/10.1124/dmd.117.079467
  8. Archer, Faith

    1. Interindividual Regulation of the Breast Cancer Resistance Protein/<em>ABCG2</em> Transporter in Term Human Placentas
      You have access
      Interindividual Regulation of the Breast Cancer Resistance Protein/ABCG2 Transporter in Term Human Placentas
      Kristin M. Bircsak, Jamie E. Moscovitz, Xia Wen, Faith Archer, Poi Yu Sofia Yuen, Moiz Mohammed, Naureen Memon, Barry I. Weinberger, Laura M. Saba, Anna M. Vetrano and Lauren M. Aleksunes
      Drug Metabolism and Disposition May 2018, 46 (5) 619-627; DOI: https://doi.org/10.1124/dmd.117.079228
  9. Audet-Delage, Yannick

    1. Post-transcriptional Regulation of UGT2B10 Hepatic Expression and Activity by Alternative Splicing
      You have access
      Post-transcriptional Regulation of UGT2B10 Hepatic Expression and Activity by Alternative Splicing
      Adrien Labriet, Eric P. Allain, Michèle Rouleau, Yannick Audet-Delage, Lyne Villeneuve and Chantal Guillemette
      Drug Metabolism and Disposition May 2018, 46 (5) 514-524; DOI: https://doi.org/10.1124/dmd.117.079921

B

  1. Beaton, Melanie D.

    1. You have access
      Apixaban and Rosuvas­­tatin Pharmacokinetics in Nonalcoholic Fatty Liver Disease
      Rommel G. Tirona, Zahra Kassam, Ruth Strapp, Mala Ramu, Catherine Zhu, Melissa Liu, Ute I. Schwarz, Richard B. Kim, Bandar Al-Judaibi and Melanie D. Beaton
      Drug Metabolism and Disposition May 2018, 46 (5) 485-492; DOI: https://doi.org/10.1124/dmd.117.079624
  2. Bircsak, Kristin M.

    1. Interindividual Regulation of the Breast Cancer Resistance Protein/<em>ABCG2</em> Transporter in Term Human Placentas
      You have access
      Interindividual Regulation of the Breast Cancer Resistance Protein/ABCG2 Transporter in Term Human Placentas
      Kristin M. Bircsak, Jamie E. Moscovitz, Xia Wen, Faith Archer, Poi Yu Sofia Yuen, Moiz Mohammed, Naureen Memon, Barry I. Weinberger, Laura M. Saba, Anna M. Vetrano and Lauren M. Aleksunes
      Drug Metabolism and Disposition May 2018, 46 (5) 619-627; DOI: https://doi.org/10.1124/dmd.117.079228
  3. Bourbonais, Francis

    1. You have access
      Comparison of Proteomic Quantification Approaches for Hepatic Drug Transporters: Multiplexed Global Quantitation Correlates with Targeted Proteomic Quantitation
      Anna Vildhede, Chuong Nguyen, Brian K. Erickson, Ryan C. Kunz, Richard Jones, Emi Kimoto, Francis Bourbonais, A. David Rodrigues and Manthena V.S. Varma
      Drug Metabolism and Disposition May 2018, 46 (5) 692-696; DOI: https://doi.org/10.1124/dmd.117.079285

C

  1. Cai, Qingyun

    1. You have access
      A Promising Microtubule Inhibitor Deoxypodophyllotoxin Exhibits Better Efficacy to Multidrug-Resistant Breast Cancer than Paclitaxel via Avoiding Efflux Transport
      Xiaojie Zang, Guangji Wang, Qingyun Cai, Xiao Zheng, Jingwei Zhang, Qianying Chen, Baojin Wu, Xiong Zhu, Haiping Hao and Fang Zhou
      Drug Metabolism and Disposition May 2018, 46 (5) 542-551; DOI: https://doi.org/10.1124/dmd.117.079442
  2. Cech, Nadja B.

    1. You have access
      Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation
      Dan-Dan Tian, Joshua J. Kellogg, Neşe Okut, Nicholas H. Oberlies, Nadja B. Cech, Danny D. Shen, Jeannine S. McCune and Mary F. Paine
      Drug Metabolism and Disposition May 2018, 46 (5) 552-560; DOI: https://doi.org/10.1124/dmd.117.079491
  3. Chen, Kaiwen

    1. You have access
      Identification of a NFκB Inhibition Site on the Proximal Promoter Region of Human Organic Anion Transporting Polypeptide 1A2 Coding Gene SLCO1A2
      Zhaojian Xiang, Weike Li, Lixue Wang, Jicai Yi, Kaiwen Chen and Mei Hong
      Drug Metabolism and Disposition May 2018, 46 (5) 643-651; DOI: https://doi.org/10.1124/dmd.117.078832
  4. Chen, Qianying

    1. You have access
      A Promising Microtubule Inhibitor Deoxypodophyllotoxin Exhibits Better Efficacy to Multidrug-Resistant Breast Cancer than Paclitaxel via Avoiding Efflux Transport
      Xiaojie Zang, Guangji Wang, Qingyun Cai, Xiao Zheng, Jingwei Zhang, Qianying Chen, Baojin Wu, Xiong Zhu, Haiping Hao and Fang Zhou
      Drug Metabolism and Disposition May 2018, 46 (5) 542-551; DOI: https://doi.org/10.1124/dmd.117.079442
  5. Chen, Yuan

    1. You have access
      Intravital Multiphoton Microscopy with Fluorescent Bile Salts in Rats as an In Vivo Biomarker for Hepatobiliary Transport Inhibition
      Jennifer Ryan, Ryan E. Morgan, Yuan Chen, Laurie P. Volak, Robert T. Dunn and Kenneth W. Dunn
      Drug Metabolism and Disposition May 2018, 46 (5) 704-718; DOI: https://doi.org/10.1124/dmd.117.079277
  6. Cook-Rostie, Nicholas

    1. You have access
      Brain Distribution of a Novel MEK Inhibitor E6201: Implications in the Treatment of Melanoma Brain Metastases
      Gautham Gampa, Minjee Kim, Nicholas Cook-Rostie, Janice K. Laramy, Jann N. Sarkaria, Linda Paradiso, Louis DePalatis and William F. Elmquist
      Drug Metabolism and Disposition May 2018, 46 (5) 658-666; DOI: https://doi.org/10.1124/dmd.117.079194
  7. Crawford, Rebecca R.

    1. You have access
      Beyond Competitive Inhibition: Regulation of ABC Transporters by Kinases and Protein-Protein Interactions as Potential Mechanisms of Drug-Drug Interactions
      Rebecca R. Crawford, Praveen K. Potukuchi, Erin G. Schuetz and John D. Schuetz
      Drug Metabolism and Disposition May 2018, 46 (5) 567-580; DOI: https://doi.org/10.1124/dmd.118.080663
  8. Cui, Julia Yue

    1. You have access
      Physiological Regulation of Drug Metabolism and Transport: Pregnancy, Microbiome, Inflammation, Infection, and Fasting
      Edward T. Morgan, Joseph L. Dempsey, Sylvie M. Mimche, Tracey J. Lamb, Supriya Kulkarni, Julia Yue Cui, Hyunyoung Jeong and Angela L. Slitt
      Drug Metabolism and Disposition May 2018, 46 (5) 503-513; DOI: https://doi.org/10.1124/dmd.117.079905
  9. Cui, Yilong

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408

D

  1. Dabaghie, Dina

    1. Open Access
      Expression of Organic Anion Transporter 1 or 3 in Human Kidney Proximal Tubule Cells Reduces Cisplatin Sensitivity
      Tom T. G. Nieskens, Janny G. P. Peters, Dina Dabaghie, Daphne Korte, Katja Jansen, Alexander H. Van Asbeck, Neslihan N. Tavraz, Thomas Friedrich, Frans G. M. Russel, Rosalinde Masereeuw and Martijn J. Wilmer
      Drug Metabolism and Disposition May 2018, 46 (5) 592-599; DOI: https://doi.org/10.1124/dmd.117.079384
  2. Dempsey, Joseph L.

    1. You have access
      Physiological Regulation of Drug Metabolism and Transport: Pregnancy, Microbiome, Inflammation, Infection, and Fasting
      Edward T. Morgan, Joseph L. Dempsey, Sylvie M. Mimche, Tracey J. Lamb, Supriya Kulkarni, Julia Yue Cui, Hyunyoung Jeong and Angela L. Slitt
      Drug Metabolism and Disposition May 2018, 46 (5) 503-513; DOI: https://doi.org/10.1124/dmd.117.079905
  3. DePalatis, Louis

    1. You have access
      Brain Distribution of a Novel MEK Inhibitor E6201: Implications in the Treatment of Melanoma Brain Metastases
      Gautham Gampa, Minjee Kim, Nicholas Cook-Rostie, Janice K. Laramy, Jann N. Sarkaria, Linda Paradiso, Louis DePalatis and William F. Elmquist
      Drug Metabolism and Disposition May 2018, 46 (5) 658-666; DOI: https://doi.org/10.1124/dmd.117.079194
  4. Dunn, Kenneth W.

    1. You have access
      Intravital Multiphoton Microscopy with Fluorescent Bile Salts in Rats as an In Vivo Biomarker for Hepatobiliary Transport Inhibition
      Jennifer Ryan, Ryan E. Morgan, Yuan Chen, Laurie P. Volak, Robert T. Dunn and Kenneth W. Dunn
      Drug Metabolism and Disposition May 2018, 46 (5) 704-718; DOI: https://doi.org/10.1124/dmd.117.079277
  5. Dunn, Robert T.

    1. You have access
      Intravital Multiphoton Microscopy with Fluorescent Bile Salts in Rats as an In Vivo Biomarker for Hepatobiliary Transport Inhibition
      Jennifer Ryan, Ryan E. Morgan, Yuan Chen, Laurie P. Volak, Robert T. Dunn and Kenneth W. Dunn
      Drug Metabolism and Disposition May 2018, 46 (5) 704-718; DOI: https://doi.org/10.1124/dmd.117.079277

E

  1. Eclov, Rachel J.

    1. You have access
      Rare Variants in the ABCG2 Promoter Modulate In Vivo Activity
      Rachel J. Eclov, Mee J. Kim, Robin Smith, Nadav Ahituv and Deanna L. Kroetz
      Drug Metabolism and Disposition May 2018, 46 (5) 636-642; DOI: https://doi.org/10.1124/dmd.117.079541
  2. El-Kattan, Ayman F.

    1. You have access
      Navigating Transporter Sciences in Pharmacokinetics Characterization Using the Extended Clearance Classification System
      Ayman F. El-Kattan and Manthena V. S. Varma
      Drug Metabolism and Disposition May 2018, 46 (5) 729-739; DOI: https://doi.org/10.1124/dmd.117.080044
  3. Elmquist, William F.

    1. You have access
      Brain Distribution of a Novel MEK Inhibitor E6201: Implications in the Treatment of Melanoma Brain Metastases
      Gautham Gampa, Minjee Kim, Nicholas Cook-Rostie, Janice K. Laramy, Jann N. Sarkaria, Linda Paradiso, Louis DePalatis and William F. Elmquist
      Drug Metabolism and Disposition May 2018, 46 (5) 658-666; DOI: https://doi.org/10.1124/dmd.117.079194
  4. Enomoto, Masaru

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
  5. Erickson, Brian K.

    1. You have access
      Comparison of Proteomic Quantification Approaches for Hepatic Drug Transporters: Multiplexed Global Quantitation Correlates with Targeted Proteomic Quantitation
      Anna Vildhede, Chuong Nguyen, Brian K. Erickson, Ryan C. Kunz, Richard Jones, Emi Kimoto, Francis Bourbonais, A. David Rodrigues and Manthena V.S. Varma
      Drug Metabolism and Disposition May 2018, 46 (5) 692-696; DOI: https://doi.org/10.1124/dmd.117.079285

F

  1. Fate, Gwendolyn D.

    1. You have access
      Biosynthesis and Identification of Metabolites of Maraviroc and Their Use in Experiments to Delineate the Relative Contributions of Cytochrome P4503A4 versus 3A5
      Elaine Tseng, Gwendolyn D. Fate, Gregory S. Walker, Theunis C. Goosen and R. Scott Obach
      Drug Metabolism and Disposition May 2018, 46 (5) 493-502; DOI: https://doi.org/10.1124/dmd.117.079855
  2. Follman, Kristin E.

    1. You have access
      Prediction of the Effects of Renal Impairment on Clearance for Organic Cation Drugs that Undergo Renal Secretion: A Simulation-Based Study
      Kristin E. Follman and Marilyn E. Morris
      Drug Metabolism and Disposition May 2018, 46 (5) 758-769; DOI: https://doi.org/10.1124/dmd.117.079558
  3. Friedrich, Thomas

    1. Open Access
      Expression of Organic Anion Transporter 1 or 3 in Human Kidney Proximal Tubule Cells Reduces Cisplatin Sensitivity
      Tom T. G. Nieskens, Janny G. P. Peters, Dina Dabaghie, Daphne Korte, Katja Jansen, Alexander H. Van Asbeck, Neslihan N. Tavraz, Thomas Friedrich, Frans G. M. Russel, Rosalinde Masereeuw and Martijn J. Wilmer
      Drug Metabolism and Disposition May 2018, 46 (5) 592-599; DOI: https://doi.org/10.1124/dmd.117.079384
  4. Fukuchi, Yukina

    1. You have access
      Sandwich-Cultured Hepatocytes for Mechanistic Understanding of Hepatic Disposition of Parent Drugs and Metabolites by Transporter–Enzyme Interplay
      Norikazu Matsunaga, Yukina Fukuchi, Haruo Imawaka and Ikumi Tamai
      Drug Metabolism and Disposition May 2018, 46 (5) 680-691; DOI: https://doi.org/10.1124/dmd.117.079236
  5. Futatsugi, Azusa

    1. You have access
      Evaluation of Alteration in Hepatic and Intestinal BCRP Function In Vivo from ABCG2 c.421C>A Polymorphism Based on PBPK Analysis of Rosuvastatin
      Azusa Futatsugi, Kota Toshimoto, Takashi Yoshikado, Yuichi Sugiyama and Yukio Kato
      Drug Metabolism and Disposition May 2018, 46 (5) 749-757; DOI: https://doi.org/10.1124/dmd.117.078816

G

  1. Gampa, Gautham

    1. You have access
      Brain Distribution of a Novel MEK Inhibitor E6201: Implications in the Treatment of Melanoma Brain Metastases
      Gautham Gampa, Minjee Kim, Nicholas Cook-Rostie, Janice K. Laramy, Jann N. Sarkaria, Linda Paradiso, Louis DePalatis and William F. Elmquist
      Drug Metabolism and Disposition May 2018, 46 (5) 658-666; DOI: https://doi.org/10.1124/dmd.117.079194
  2. Gao, Chunying

    1. You have access
      Hepatic Transport of 25-Hydroxyvitamin D3 Conjugates: A Mechanism of 25-Hydroxyvitamin D3 Delivery to the Intestinal Tract
      Chunying Gao, Michael Z. Liao, Lyrialle W. Han, Kenneth E. Thummel and Qingcheng Mao
      Drug Metabolism and Disposition May 2018, 46 (5) 581-591; DOI: https://doi.org/10.1124/dmd.117.078881
  3. Gillen, Michael

    1. You have access
      Metabolism and Disposition of Verinurad, a Uric Acid Reabsorption Inhibitor, in Humans
      Caroline A. Lee, Chun Yang, Vishal Shah, Zancong Shen, David M. Wilson, Traci M. Ostertag, Jean-Luc Girardet, Jesse Hall and Michael Gillen
      Drug Metabolism and Disposition May 2018, 46 (5) 532-541; DOI: https://doi.org/10.1124/dmd.117.078220
  4. Girardet, Jean-Luc

    1. You have access
      Metabolism and Disposition of Verinurad, a Uric Acid Reabsorption Inhibitor, in Humans
      Caroline A. Lee, Chun Yang, Vishal Shah, Zancong Shen, David M. Wilson, Traci M. Ostertag, Jean-Luc Girardet, Jesse Hall and Michael Gillen
      Drug Metabolism and Disposition May 2018, 46 (5) 532-541; DOI: https://doi.org/10.1124/dmd.117.078220
  5. Goosen, Theunis C.

    1. You have access
      Biosynthesis and Identification of Metabolites of Maraviroc and Their Use in Experiments to Delineate the Relative Contributions of Cytochrome P4503A4 versus 3A5
      Elaine Tseng, Gwendolyn D. Fate, Gregory S. Walker, Theunis C. Goosen and R. Scott Obach
      Drug Metabolism and Disposition May 2018, 46 (5) 493-502; DOI: https://doi.org/10.1124/dmd.117.079855
  6. Govindarajan, Rajgopal

    1. Open Access
      Identification of Structural and Molecular Features Involved in the Transport of 3′-Deoxy-Nucleoside Analogs by Human Equilibrative Nucleoside Transporter 3
      MD Fazlur Rahman, Radhika Raj and Rajgopal Govindarajan
      Drug Metabolism and Disposition May 2018, 46 (5) 600-609; DOI: https://doi.org/10.1124/dmd.117.079400
  7. Guillemette, Chantal

    1. Post-transcriptional Regulation of UGT2B10 Hepatic Expression and Activity by Alternative Splicing
      You have access
      Post-transcriptional Regulation of UGT2B10 Hepatic Expression and Activity by Alternative Splicing
      Adrien Labriet, Eric P. Allain, Michèle Rouleau, Yannick Audet-Delage, Lyne Villeneuve and Chantal Guillemette
      Drug Metabolism and Disposition May 2018, 46 (5) 514-524; DOI: https://doi.org/10.1124/dmd.117.079921
  8. Guo, Dayong

    1. You have access
      Generation and Characterization of a CYP2C11-Null Rat Model by Using the CRISPR/Cas9 Method
      Yuan Wei, Li Yang, Xiaoyan Zhang, Danjuan Sui, Changsuo Wang, Kai Wang, Mangting Shan, Dayong Guo and Hongyu Wang
      Drug Metabolism and Disposition May 2018, 46 (5) 525-531; DOI: https://doi.org/10.1124/dmd.117.078444

H

  1. Hall, Jesse

    1. You have access
      Metabolism and Disposition of Verinurad, a Uric Acid Reabsorption Inhibitor, in Humans
      Caroline A. Lee, Chun Yang, Vishal Shah, Zancong Shen, David M. Wilson, Traci M. Ostertag, Jean-Luc Girardet, Jesse Hall and Michael Gillen
      Drug Metabolism and Disposition May 2018, 46 (5) 532-541; DOI: https://doi.org/10.1124/dmd.117.078220
  2. Han, Lyrialle W.

    1. You have access
      Hepatic Transport of 25-Hydroxyvitamin D3 Conjugates: A Mechanism of 25-Hydroxyvitamin D3 Delivery to the Intestinal Tract
      Chunying Gao, Michael Z. Liao, Lyrialle W. Han, Kenneth E. Thummel and Qingcheng Mao
      Drug Metabolism and Disposition May 2018, 46 (5) 581-591; DOI: https://doi.org/10.1124/dmd.117.078881
  3. Hao, Haiping

    1. You have access
      A Promising Microtubule Inhibitor Deoxypodophyllotoxin Exhibits Better Efficacy to Multidrug-Resistant Breast Cancer than Paclitaxel via Avoiding Efflux Transport
      Xiaojie Zang, Guangji Wang, Qingyun Cai, Xiao Zheng, Jingwei Zhang, Qianying Chen, Baojin Wu, Xiong Zhu, Haiping Hao and Fang Zhou
      Drug Metabolism and Disposition May 2018, 46 (5) 542-551; DOI: https://doi.org/10.1124/dmd.117.079442
  4. Hirota, Takeshi

    1. You have access
      Interindividual Differences in the Expression of ATP-Binding Cassette and Solute Carrier Family Transporters in Human Skin: DNA Methylation Regulates Transcriptional Activity of the Human ABCC3 Gene
      Tomoki Takechi, Takeshi Hirota, Tatsuya Sakai, Natsumi Maeda, Daisuke Kobayashi and Ichiro Ieiri
      Drug Metabolism and Disposition May 2018, 46 (5) 628-635; DOI: https://doi.org/10.1124/dmd.117.079061
  5. Hisaka, Akihiro

    1. You have access
      Physiologically Based Pharmacokinetic Modeling of Bosentan Identifies the Saturable Hepatic Uptake As a Major Contributor to Its Nonlinear Pharmacokinetics
      Masanobu Sato, Kota Toshimoto, Atsuko Tomaru, Takashi Yoshikado, Yuta Tanaka, Akihiro Hisaka, Wooin Lee and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2018, 46 (5) 740-748; DOI: https://doi.org/10.1124/dmd.117.078972
  6. Holmstock, Nico

    1. You have access
      MRP2 Inhibition by HIV Protease Inhibitors in Rat and Human Hepatocytes: A Quantitative Confocal Microscopy Study
      Nico Holmstock, Marlies Oorts, Jan Snoeys and Pieter Annaert
      Drug Metabolism and Disposition May 2018, 46 (5) 697-703; DOI: https://doi.org/10.1124/dmd.117.079467
  7. Hong, Mei

    1. You have access
      Identification of a NFκB Inhibition Site on the Proximal Promoter Region of Human Organic Anion Transporting Polypeptide 1A2 Coding Gene SLCO1A2
      Zhaojian Xiang, Weike Li, Lixue Wang, Jicai Yi, Kaiwen Chen and Mei Hong
      Drug Metabolism and Disposition May 2018, 46 (5) 643-651; DOI: https://doi.org/10.1124/dmd.117.078832

I

  1. Ieiri, Ichiro

    1. You have access
      Interindividual Differences in the Expression of ATP-Binding Cassette and Solute Carrier Family Transporters in Human Skin: DNA Methylation Regulates Transcriptional Activity of the Human ABCC3 Gene
      Tomoki Takechi, Takeshi Hirota, Tatsuya Sakai, Natsumi Maeda, Daisuke Kobayashi and Ichiro Ieiri
      Drug Metabolism and Disposition May 2018, 46 (5) 628-635; DOI: https://doi.org/10.1124/dmd.117.079061
  2. Imaoka, Tomoki

    1. You have access
      Curcumin as an In Vivo Selective Intestinal Breast Cancer Resistance Protein Inhibitor in Cynomolgus Monkeys
      Tsuyoshi Karibe, Tomoki Imaoka, Koji Abe and Osamu Ando
      Drug Metabolism and Disposition May 2018, 46 (5) 667-679; DOI: https://doi.org/10.1124/dmd.117.078931
  3. Imawaka, Haruo

    1. You have access
      Sandwich-Cultured Hepatocytes for Mechanistic Understanding of Hepatic Disposition of Parent Drugs and Metabolites by Transporter–Enzyme Interplay
      Norikazu Matsunaga, Yukina Fukuchi, Haruo Imawaka and Ikumi Tamai
      Drug Metabolism and Disposition May 2018, 46 (5) 680-691; DOI: https://doi.org/10.1124/dmd.117.079236
  4. Irie, Satsuki

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
  5. Ishii, Akira

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408

J

  1. Jansen, Katja

    1. Open Access
      Expression of Organic Anion Transporter 1 or 3 in Human Kidney Proximal Tubule Cells Reduces Cisplatin Sensitivity
      Tom T. G. Nieskens, Janny G. P. Peters, Dina Dabaghie, Daphne Korte, Katja Jansen, Alexander H. Van Asbeck, Neslihan N. Tavraz, Thomas Friedrich, Frans G. M. Russel, Rosalinde Masereeuw and Martijn J. Wilmer
      Drug Metabolism and Disposition May 2018, 46 (5) 592-599; DOI: https://doi.org/10.1124/dmd.117.079384
  2. Jeong, Hyunyoung

    1. You have access
      Physiological Regulation of Drug Metabolism and Transport: Pregnancy, Microbiome, Inflammation, Infection, and Fasting
      Edward T. Morgan, Joseph L. Dempsey, Sylvie M. Mimche, Tracey J. Lamb, Supriya Kulkarni, Julia Yue Cui, Hyunyoung Jeong and Angela L. Slitt
      Drug Metabolism and Disposition May 2018, 46 (5) 503-513; DOI: https://doi.org/10.1124/dmd.117.079905
  3. Jones, Richard

    1. You have access
      Comparison of Proteomic Quantification Approaches for Hepatic Drug Transporters: Multiplexed Global Quantitation Correlates with Targeted Proteomic Quantitation
      Anna Vildhede, Chuong Nguyen, Brian K. Erickson, Ryan C. Kunz, Richard Jones, Emi Kimoto, Francis Bourbonais, A. David Rodrigues and Manthena V.S. Varma
      Drug Metabolism and Disposition May 2018, 46 (5) 692-696; DOI: https://doi.org/10.1124/dmd.117.079285

K

  1. Kaneko, Ken-ichi

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
  2. Karibe, Tsuyoshi

    1. You have access
      Curcumin as an In Vivo Selective Intestinal Breast Cancer Resistance Protein Inhibitor in Cynomolgus Monkeys
      Tsuyoshi Karibe, Tomoki Imaoka, Koji Abe and Osamu Ando
      Drug Metabolism and Disposition May 2018, 46 (5) 667-679; DOI: https://doi.org/10.1124/dmd.117.078931
  3. Kassam, Zahra

    1. You have access
      Apixaban and Rosuvas­­tatin Pharmacokinetics in Nonalcoholic Fatty Liver Disease
      Rommel G. Tirona, Zahra Kassam, Ruth Strapp, Mala Ramu, Catherine Zhu, Melissa Liu, Ute I. Schwarz, Richard B. Kim, Bandar Al-Judaibi and Melanie D. Beaton
      Drug Metabolism and Disposition May 2018, 46 (5) 485-492; DOI: https://doi.org/10.1124/dmd.117.079624
  4. Katayama, Yumiko

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
  5. Kato, Yukio

    1. You have access
      Evaluation of Alteration in Hepatic and Intestinal BCRP Function In Vivo from ABCG2 c.421C>A Polymorphism Based on PBPK Analysis of Rosuvastatin
      Azusa Futatsugi, Kota Toshimoto, Takashi Yoshikado, Yuichi Sugiyama and Yukio Kato
      Drug Metabolism and Disposition May 2018, 46 (5) 749-757; DOI: https://doi.org/10.1124/dmd.117.078816
  6. Kawabe, Joji

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
  7. Kawada, Norifumi

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
  8. Kawahata, Hideki

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
  9. Kawamura, Etsushi

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
  10. Kellogg, Joshua J.

    1. You have access
      Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation
      Dan-Dan Tian, Joshua J. Kellogg, Neşe Okut, Nicholas H. Oberlies, Nadja B. Cech, Danny D. Shen, Jeannine S. McCune and Mary F. Paine
      Drug Metabolism and Disposition May 2018, 46 (5) 552-560; DOI: https://doi.org/10.1124/dmd.117.079491
  11. Kim, Mee J.

    1. You have access
      Rare Variants in the ABCG2 Promoter Modulate In Vivo Activity
      Rachel J. Eclov, Mee J. Kim, Robin Smith, Nadav Ahituv and Deanna L. Kroetz
      Drug Metabolism and Disposition May 2018, 46 (5) 636-642; DOI: https://doi.org/10.1124/dmd.117.079541
  12. Kim, Minjee

    1. You have access
      Brain Distribution of a Novel MEK Inhibitor E6201: Implications in the Treatment of Melanoma Brain Metastases
      Gautham Gampa, Minjee Kim, Nicholas Cook-Rostie, Janice K. Laramy, Jann N. Sarkaria, Linda Paradiso, Louis DePalatis and William F. Elmquist
      Drug Metabolism and Disposition May 2018, 46 (5) 658-666; DOI: https://doi.org/10.1124/dmd.117.079194
  13. Kim, Richard B.

    1. You have access
      Apixaban and Rosuvas­­tatin Pharmacokinetics in Nonalcoholic Fatty Liver Disease
      Rommel G. Tirona, Zahra Kassam, Ruth Strapp, Mala Ramu, Catherine Zhu, Melissa Liu, Ute I. Schwarz, Richard B. Kim, Bandar Al-Judaibi and Melanie D. Beaton
      Drug Metabolism and Disposition May 2018, 46 (5) 485-492; DOI: https://doi.org/10.1124/dmd.117.079624
  14. Kimoto, Emi

    1. You have access
      Comparison of Proteomic Quantification Approaches for Hepatic Drug Transporters: Multiplexed Global Quantitation Correlates with Targeted Proteomic Quantitation
      Anna Vildhede, Chuong Nguyen, Brian K. Erickson, Ryan C. Kunz, Richard Jones, Emi Kimoto, Francis Bourbonais, A. David Rodrigues and Manthena V.S. Varma
      Drug Metabolism and Disposition May 2018, 46 (5) 692-696; DOI: https://doi.org/10.1124/dmd.117.079285
  15. Kobayashi, Daisuke

    1. You have access
      Interindividual Differences in the Expression of ATP-Binding Cassette and Solute Carrier Family Transporters in Human Skin: DNA Methylation Regulates Transcriptional Activity of the Human ABCC3 Gene
      Tomoki Takechi, Takeshi Hirota, Tatsuya Sakai, Natsumi Maeda, Daisuke Kobayashi and Ichiro Ieiri
      Drug Metabolism and Disposition May 2018, 46 (5) 628-635; DOI: https://doi.org/10.1124/dmd.117.079061
  16. Korte, Daphne

    1. Open Access
      Expression of Organic Anion Transporter 1 or 3 in Human Kidney Proximal Tubule Cells Reduces Cisplatin Sensitivity
      Tom T. G. Nieskens, Janny G. P. Peters, Dina Dabaghie, Daphne Korte, Katja Jansen, Alexander H. Van Asbeck, Neslihan N. Tavraz, Thomas Friedrich, Frans G. M. Russel, Rosalinde Masereeuw and Martijn J. Wilmer
      Drug Metabolism and Disposition May 2018, 46 (5) 592-599; DOI: https://doi.org/10.1124/dmd.117.079384
  17. Kroetz, Deanna L.

    1. You have access
      Rare Variants in the ABCG2 Promoter Modulate In Vivo Activity
      Rachel J. Eclov, Mee J. Kim, Robin Smith, Nadav Ahituv and Deanna L. Kroetz
      Drug Metabolism and Disposition May 2018, 46 (5) 636-642; DOI: https://doi.org/10.1124/dmd.117.079541
  18. Kulkarni, Supriya

    1. You have access
      Physiological Regulation of Drug Metabolism and Transport: Pregnancy, Microbiome, Inflammation, Infection, and Fasting
      Edward T. Morgan, Joseph L. Dempsey, Sylvie M. Mimche, Tracey J. Lamb, Supriya Kulkarni, Julia Yue Cui, Hyunyoung Jeong and Angela L. Slitt
      Drug Metabolism and Disposition May 2018, 46 (5) 503-513; DOI: https://doi.org/10.1124/dmd.117.079905
  19. Kunz, Ryan C.

    1. You have access
      Comparison of Proteomic Quantification Approaches for Hepatic Drug Transporters: Multiplexed Global Quantitation Correlates with Targeted Proteomic Quantitation
      Anna Vildhede, Chuong Nguyen, Brian K. Erickson, Ryan C. Kunz, Richard Jones, Emi Kimoto, Francis Bourbonais, A. David Rodrigues and Manthena V.S. Varma
      Drug Metabolism and Disposition May 2018, 46 (5) 692-696; DOI: https://doi.org/10.1124/dmd.117.079285
  20. Kusuhara, Hiroyuki

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
    2. You have access
      Organic Anion Transporting Polypeptide 1a4 is Responsible for the Hepatic Uptake of Cardiac Glycosides in Mice
      Junichi Takano, Kazuya Maeda, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2018, 46 (5) 652-657; DOI: https://doi.org/10.1124/dmd.117.079483

L

  1. Labriet, Adrien

    1. Post-transcriptional Regulation of UGT2B10 Hepatic Expression and Activity by Alternative Splicing
      You have access
      Post-transcriptional Regulation of UGT2B10 Hepatic Expression and Activity by Alternative Splicing
      Adrien Labriet, Eric P. Allain, Michèle Rouleau, Yannick Audet-Delage, Lyne Villeneuve and Chantal Guillemette
      Drug Metabolism and Disposition May 2018, 46 (5) 514-524; DOI: https://doi.org/10.1124/dmd.117.079921
  2. Lai, Yurong

    1. You have access
      Drug Transporters in Xenobiotic Disposition and Pharmacokinetic Prediction
      Qingcheng Mao, Yurong Lai and Joanne Wang
      Drug Metabolism and Disposition May 2018, 46 (5) 561-566; DOI: https://doi.org/10.1124/dmd.118.081356
  3. Lamb, Tracey J.

    1. You have access
      Physiological Regulation of Drug Metabolism and Transport: Pregnancy, Microbiome, Inflammation, Infection, and Fasting
      Edward T. Morgan, Joseph L. Dempsey, Sylvie M. Mimche, Tracey J. Lamb, Supriya Kulkarni, Julia Yue Cui, Hyunyoung Jeong and Angela L. Slitt
      Drug Metabolism and Disposition May 2018, 46 (5) 503-513; DOI: https://doi.org/10.1124/dmd.117.079905
  4. Laramy, Janice K.

    1. You have access
      Brain Distribution of a Novel MEK Inhibitor E6201: Implications in the Treatment of Melanoma Brain Metastases
      Gautham Gampa, Minjee Kim, Nicholas Cook-Rostie, Janice K. Laramy, Jann N. Sarkaria, Linda Paradiso, Louis DePalatis and William F. Elmquist
      Drug Metabolism and Disposition May 2018, 46 (5) 658-666; DOI: https://doi.org/10.1124/dmd.117.079194
  5. Lee, Caroline A.

    1. You have access
      Metabolism and Disposition of Verinurad, a Uric Acid Reabsorption Inhibitor, in Humans
      Caroline A. Lee, Chun Yang, Vishal Shah, Zancong Shen, David M. Wilson, Traci M. Ostertag, Jean-Luc Girardet, Jesse Hall and Michael Gillen
      Drug Metabolism and Disposition May 2018, 46 (5) 532-541; DOI: https://doi.org/10.1124/dmd.117.078220
  6. Lee, Wooin

    1. You have access
      Physiologically Based Pharmacokinetic Modeling of Bosentan Identifies the Saturable Hepatic Uptake As a Major Contributor to Its Nonlinear Pharmacokinetics
      Masanobu Sato, Kota Toshimoto, Atsuko Tomaru, Takashi Yoshikado, Yuta Tanaka, Akihiro Hisaka, Wooin Lee and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2018, 46 (5) 740-748; DOI: https://doi.org/10.1124/dmd.117.078972
  7. Li, Weike

    1. You have access
      Identification of a NFκB Inhibition Site on the Proximal Promoter Region of Human Organic Anion Transporting Polypeptide 1A2 Coding Gene SLCO1A2
      Zhaojian Xiang, Weike Li, Lixue Wang, Jicai Yi, Kaiwen Chen and Mei Hong
      Drug Metabolism and Disposition May 2018, 46 (5) 643-651; DOI: https://doi.org/10.1124/dmd.117.078832
  8. Liao, Michael Z.

    1. You have access
      Hepatic Transport of 25-Hydroxyvitamin D3 Conjugates: A Mechanism of 25-Hydroxyvitamin D3 Delivery to the Intestinal Tract
      Chunying Gao, Michael Z. Liao, Lyrialle W. Han, Kenneth E. Thummel and Qingcheng Mao
      Drug Metabolism and Disposition May 2018, 46 (5) 581-591; DOI: https://doi.org/10.1124/dmd.117.078881
  9. Liu, Melissa

    1. You have access
      Apixaban and Rosuvas­­tatin Pharmacokinetics in Nonalcoholic Fatty Liver Disease
      Rommel G. Tirona, Zahra Kassam, Ruth Strapp, Mala Ramu, Catherine Zhu, Melissa Liu, Ute I. Schwarz, Richard B. Kim, Bandar Al-Judaibi and Melanie D. Beaton
      Drug Metabolism and Disposition May 2018, 46 (5) 485-492; DOI: https://doi.org/10.1124/dmd.117.079624

M

  1. Maeda, Kazuya

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
    2. You have access
      Organic Anion Transporting Polypeptide 1a4 is Responsible for the Hepatic Uptake of Cardiac Glycosides in Mice
      Junichi Takano, Kazuya Maeda, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2018, 46 (5) 652-657; DOI: https://doi.org/10.1124/dmd.117.079483
  2. Maeda, Natsumi

    1. You have access
      Interindividual Differences in the Expression of ATP-Binding Cassette and Solute Carrier Family Transporters in Human Skin: DNA Methylation Regulates Transcriptional Activity of the Human ABCC3 Gene
      Tomoki Takechi, Takeshi Hirota, Tatsuya Sakai, Natsumi Maeda, Daisuke Kobayashi and Ichiro Ieiri
      Drug Metabolism and Disposition May 2018, 46 (5) 628-635; DOI: https://doi.org/10.1124/dmd.117.079061
  3. Mao, Qingcheng

    1. You have access
      Hepatic Transport of 25-Hydroxyvitamin D3 Conjugates: A Mechanism of 25-Hydroxyvitamin D3 Delivery to the Intestinal Tract
      Chunying Gao, Michael Z. Liao, Lyrialle W. Han, Kenneth E. Thummel and Qingcheng Mao
      Drug Metabolism and Disposition May 2018, 46 (5) 581-591; DOI: https://doi.org/10.1124/dmd.117.078881
    2. You have access
      Drug Transporters in Xenobiotic Disposition and Pharmacokinetic Prediction
      Qingcheng Mao, Yurong Lai and Joanne Wang
      Drug Metabolism and Disposition May 2018, 46 (5) 561-566; DOI: https://doi.org/10.1124/dmd.118.081356
  4. Masereeuw, Rosalinde

    1. Open Access
      Expression of Organic Anion Transporter 1 or 3 in Human Kidney Proximal Tubule Cells Reduces Cisplatin Sensitivity
      Tom T. G. Nieskens, Janny G. P. Peters, Dina Dabaghie, Daphne Korte, Katja Jansen, Alexander H. Van Asbeck, Neslihan N. Tavraz, Thomas Friedrich, Frans G. M. Russel, Rosalinde Masereeuw and Martijn J. Wilmer
      Drug Metabolism and Disposition May 2018, 46 (5) 592-599; DOI: https://doi.org/10.1124/dmd.117.079384
  5. Matsunaga, Norikazu

    1. You have access
      Sandwich-Cultured Hepatocytes for Mechanistic Understanding of Hepatic Disposition of Parent Drugs and Metabolites by Transporter–Enzyme Interplay
      Norikazu Matsunaga, Yukina Fukuchi, Haruo Imawaka and Ikumi Tamai
      Drug Metabolism and Disposition May 2018, 46 (5) 680-691; DOI: https://doi.org/10.1124/dmd.117.079236
  6. McCune, Jeannine S.

    1. You have access
      Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation
      Dan-Dan Tian, Joshua J. Kellogg, Neşe Okut, Nicholas H. Oberlies, Nadja B. Cech, Danny D. Shen, Jeannine S. McCune and Mary F. Paine
      Drug Metabolism and Disposition May 2018, 46 (5) 552-560; DOI: https://doi.org/10.1124/dmd.117.079491
  7. Memon, Naureen

    1. Interindividual Regulation of the Breast Cancer Resistance Protein/<em>ABCG2</em> Transporter in Term Human Placentas
      You have access
      Interindividual Regulation of the Breast Cancer Resistance Protein/ABCG2 Transporter in Term Human Placentas
      Kristin M. Bircsak, Jamie E. Moscovitz, Xia Wen, Faith Archer, Poi Yu Sofia Yuen, Moiz Mohammed, Naureen Memon, Barry I. Weinberger, Laura M. Saba, Anna M. Vetrano and Lauren M. Aleksunes
      Drug Metabolism and Disposition May 2018, 46 (5) 619-627; DOI: https://doi.org/10.1124/dmd.117.079228
  8. Mimche, Sylvie M.

    1. You have access
      Physiological Regulation of Drug Metabolism and Transport: Pregnancy, Microbiome, Inflammation, Infection, and Fasting
      Edward T. Morgan, Joseph L. Dempsey, Sylvie M. Mimche, Tracey J. Lamb, Supriya Kulkarni, Julia Yue Cui, Hyunyoung Jeong and Angela L. Slitt
      Drug Metabolism and Disposition May 2018, 46 (5) 503-513; DOI: https://doi.org/10.1124/dmd.117.079905
  9. Miyake, Takeshi

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
  10. Mohammed, Moiz

    1. Interindividual Regulation of the Breast Cancer Resistance Protein/<em>ABCG2</em> Transporter in Term Human Placentas
      You have access
      Interindividual Regulation of the Breast Cancer Resistance Protein/ABCG2 Transporter in Term Human Placentas
      Kristin M. Bircsak, Jamie E. Moscovitz, Xia Wen, Faith Archer, Poi Yu Sofia Yuen, Moiz Mohammed, Naureen Memon, Barry I. Weinberger, Laura M. Saba, Anna M. Vetrano and Lauren M. Aleksunes
      Drug Metabolism and Disposition May 2018, 46 (5) 619-627; DOI: https://doi.org/10.1124/dmd.117.079228
  11. Morgan, Edward T.

    1. You have access
      Physiological Regulation of Drug Metabolism and Transport: Pregnancy, Microbiome, Inflammation, Infection, and Fasting
      Edward T. Morgan, Joseph L. Dempsey, Sylvie M. Mimche, Tracey J. Lamb, Supriya Kulkarni, Julia Yue Cui, Hyunyoung Jeong and Angela L. Slitt
      Drug Metabolism and Disposition May 2018, 46 (5) 503-513; DOI: https://doi.org/10.1124/dmd.117.079905
  12. Morgan, Ryan E.

    1. You have access
      Intravital Multiphoton Microscopy with Fluorescent Bile Salts in Rats as an In Vivo Biomarker for Hepatobiliary Transport Inhibition
      Jennifer Ryan, Ryan E. Morgan, Yuan Chen, Laurie P. Volak, Robert T. Dunn and Kenneth W. Dunn
      Drug Metabolism and Disposition May 2018, 46 (5) 704-718; DOI: https://doi.org/10.1124/dmd.117.079277
  13. Morris, Marilyn E.

    1. You have access
      Prediction of the Effects of Renal Impairment on Clearance for Organic Cation Drugs that Undergo Renal Secretion: A Simulation-Based Study
      Kristin E. Follman and Marilyn E. Morris
      Drug Metabolism and Disposition May 2018, 46 (5) 758-769; DOI: https://doi.org/10.1124/dmd.117.079558
  14. Moscovitz, Jamie E.

    1. Interindividual Regulation of the Breast Cancer Resistance Protein/<em>ABCG2</em> Transporter in Term Human Placentas
      You have access
      Interindividual Regulation of the Breast Cancer Resistance Protein/ABCG2 Transporter in Term Human Placentas
      Kristin M. Bircsak, Jamie E. Moscovitz, Xia Wen, Faith Archer, Poi Yu Sofia Yuen, Moiz Mohammed, Naureen Memon, Barry I. Weinberger, Laura M. Saba, Anna M. Vetrano and Lauren M. Aleksunes
      Drug Metabolism and Disposition May 2018, 46 (5) 619-627; DOI: https://doi.org/10.1124/dmd.117.079228

N

  1. Nakaoka, Takayoshi

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
  2. Nguyen, Chuong

    1. You have access
      Comparison of Proteomic Quantification Approaches for Hepatic Drug Transporters: Multiplexed Global Quantitation Correlates with Targeted Proteomic Quantitation
      Anna Vildhede, Chuong Nguyen, Brian K. Erickson, Ryan C. Kunz, Richard Jones, Emi Kimoto, Francis Bourbonais, A. David Rodrigues and Manthena V.S. Varma
      Drug Metabolism and Disposition May 2018, 46 (5) 692-696; DOI: https://doi.org/10.1124/dmd.117.079285
  3. Nieskens, Tom T. G.

    1. Open Access
      Expression of Organic Anion Transporter 1 or 3 in Human Kidney Proximal Tubule Cells Reduces Cisplatin Sensitivity
      Tom T. G. Nieskens, Janny G. P. Peters, Dina Dabaghie, Daphne Korte, Katja Jansen, Alexander H. Van Asbeck, Neslihan N. Tavraz, Thomas Friedrich, Frans G. M. Russel, Rosalinde Masereeuw and Martijn J. Wilmer
      Drug Metabolism and Disposition May 2018, 46 (5) 592-599; DOI: https://doi.org/10.1124/dmd.117.079384

O

  1. Obach, R. Scott

    1. You have access
      Biosynthesis and Identification of Metabolites of Maraviroc and Their Use in Experiments to Delineate the Relative Contributions of Cytochrome P4503A4 versus 3A5
      Elaine Tseng, Gwendolyn D. Fate, Gregory S. Walker, Theunis C. Goosen and R. Scott Obach
      Drug Metabolism and Disposition May 2018, 46 (5) 493-502; DOI: https://doi.org/10.1124/dmd.117.079855
  2. Oberlies, Nicholas H.

    1. You have access
      Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation
      Dan-Dan Tian, Joshua J. Kellogg, Neşe Okut, Nicholas H. Oberlies, Nadja B. Cech, Danny D. Shen, Jeannine S. McCune and Mary F. Paine
      Drug Metabolism and Disposition May 2018, 46 (5) 552-560; DOI: https://doi.org/10.1124/dmd.117.079491
  3. Okut, Neşe

    1. You have access
      Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation
      Dan-Dan Tian, Joshua J. Kellogg, Neşe Okut, Nicholas H. Oberlies, Nadja B. Cech, Danny D. Shen, Jeannine S. McCune and Mary F. Paine
      Drug Metabolism and Disposition May 2018, 46 (5) 552-560; DOI: https://doi.org/10.1124/dmd.117.079491
  4. Oorts, Marlies

    1. You have access
      MRP2 Inhibition by HIV Protease Inhibitors in Rat and Human Hepatocytes: A Quantitative Confocal Microscopy Study
      Nico Holmstock, Marlies Oorts, Jan Snoeys and Pieter Annaert
      Drug Metabolism and Disposition May 2018, 46 (5) 697-703; DOI: https://doi.org/10.1124/dmd.117.079467
  5. Ostertag, Traci M.

    1. You have access
      Metabolism and Disposition of Verinurad, a Uric Acid Reabsorption Inhibitor, in Humans
      Caroline A. Lee, Chun Yang, Vishal Shah, Zancong Shen, David M. Wilson, Traci M. Ostertag, Jean-Luc Girardet, Jesse Hall and Michael Gillen
      Drug Metabolism and Disposition May 2018, 46 (5) 532-541; DOI: https://doi.org/10.1124/dmd.117.078220

P

  1. Paine, Mary F.

    1. You have access
      Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation
      Dan-Dan Tian, Joshua J. Kellogg, Neşe Okut, Nicholas H. Oberlies, Nadja B. Cech, Danny D. Shen, Jeannine S. McCune and Mary F. Paine
      Drug Metabolism and Disposition May 2018, 46 (5) 552-560; DOI: https://doi.org/10.1124/dmd.117.079491
  2. Paradiso, Linda

    1. You have access
      Brain Distribution of a Novel MEK Inhibitor E6201: Implications in the Treatment of Melanoma Brain Metastases
      Gautham Gampa, Minjee Kim, Nicholas Cook-Rostie, Janice K. Laramy, Jann N. Sarkaria, Linda Paradiso, Louis DePalatis and William F. Elmquist
      Drug Metabolism and Disposition May 2018, 46 (5) 658-666; DOI: https://doi.org/10.1124/dmd.117.079194
  3. Peters, Janny G. P.

    1. Open Access
      Expression of Organic Anion Transporter 1 or 3 in Human Kidney Proximal Tubule Cells Reduces Cisplatin Sensitivity
      Tom T. G. Nieskens, Janny G. P. Peters, Dina Dabaghie, Daphne Korte, Katja Jansen, Alexander H. Van Asbeck, Neslihan N. Tavraz, Thomas Friedrich, Frans G. M. Russel, Rosalinde Masereeuw and Martijn J. Wilmer
      Drug Metabolism and Disposition May 2018, 46 (5) 592-599; DOI: https://doi.org/10.1124/dmd.117.079384
  4. Potukuchi, Praveen K.

    1. You have access
      Beyond Competitive Inhibition: Regulation of ABC Transporters by Kinases and Protein-Protein Interactions as Potential Mechanisms of Drug-Drug Interactions
      Rebecca R. Crawford, Praveen K. Potukuchi, Erin G. Schuetz and John D. Schuetz
      Drug Metabolism and Disposition May 2018, 46 (5) 567-580; DOI: https://doi.org/10.1124/dmd.118.080663

R

  1. Rahman, MD Fazlur

    1. Open Access
      Identification of Structural and Molecular Features Involved in the Transport of 3′-Deoxy-Nucleoside Analogs by Human Equilibrative Nucleoside Transporter 3
      MD Fazlur Rahman, Radhika Raj and Rajgopal Govindarajan
      Drug Metabolism and Disposition May 2018, 46 (5) 600-609; DOI: https://doi.org/10.1124/dmd.117.079400
  2. Raj, Radhika

    1. Open Access
      Identification of Structural and Molecular Features Involved in the Transport of 3′-Deoxy-Nucleoside Analogs by Human Equilibrative Nucleoside Transporter 3
      MD Fazlur Rahman, Radhika Raj and Rajgopal Govindarajan
      Drug Metabolism and Disposition May 2018, 46 (5) 600-609; DOI: https://doi.org/10.1124/dmd.117.079400
  3. Ramu, Mala

    1. You have access
      Apixaban and Rosuvas­­tatin Pharmacokinetics in Nonalcoholic Fatty Liver Disease
      Rommel G. Tirona, Zahra Kassam, Ruth Strapp, Mala Ramu, Catherine Zhu, Melissa Liu, Ute I. Schwarz, Richard B. Kim, Bandar Al-Judaibi and Melanie D. Beaton
      Drug Metabolism and Disposition May 2018, 46 (5) 485-492; DOI: https://doi.org/10.1124/dmd.117.079624
  4. Rodrigues, A. David

    1. You have access
      Comparison of Proteomic Quantification Approaches for Hepatic Drug Transporters: Multiplexed Global Quantitation Correlates with Targeted Proteomic Quantitation
      Anna Vildhede, Chuong Nguyen, Brian K. Erickson, Ryan C. Kunz, Richard Jones, Emi Kimoto, Francis Bourbonais, A. David Rodrigues and Manthena V.S. Varma
      Drug Metabolism and Disposition May 2018, 46 (5) 692-696; DOI: https://doi.org/10.1124/dmd.117.079285
  5. Rouleau, Michèle

    1. Post-transcriptional Regulation of UGT2B10 Hepatic Expression and Activity by Alternative Splicing
      You have access
      Post-transcriptional Regulation of UGT2B10 Hepatic Expression and Activity by Alternative Splicing
      Adrien Labriet, Eric P. Allain, Michèle Rouleau, Yannick Audet-Delage, Lyne Villeneuve and Chantal Guillemette
      Drug Metabolism and Disposition May 2018, 46 (5) 514-524; DOI: https://doi.org/10.1124/dmd.117.079921
  6. Russel, Frans G. M.

    1. Open Access
      Expression of Organic Anion Transporter 1 or 3 in Human Kidney Proximal Tubule Cells Reduces Cisplatin Sensitivity
      Tom T. G. Nieskens, Janny G. P. Peters, Dina Dabaghie, Daphne Korte, Katja Jansen, Alexander H. Van Asbeck, Neslihan N. Tavraz, Thomas Friedrich, Frans G. M. Russel, Rosalinde Masereeuw and Martijn J. Wilmer
      Drug Metabolism and Disposition May 2018, 46 (5) 592-599; DOI: https://doi.org/10.1124/dmd.117.079384
  7. Ryan, Jennifer

    1. You have access
      Intravital Multiphoton Microscopy with Fluorescent Bile Salts in Rats as an In Vivo Biomarker for Hepatobiliary Transport Inhibition
      Jennifer Ryan, Ryan E. Morgan, Yuan Chen, Laurie P. Volak, Robert T. Dunn and Kenneth W. Dunn
      Drug Metabolism and Disposition May 2018, 46 (5) 704-718; DOI: https://doi.org/10.1124/dmd.117.079277

S

  1. Saba, Laura M.

    1. Interindividual Regulation of the Breast Cancer Resistance Protein/<em>ABCG2</em> Transporter in Term Human Placentas
      You have access
      Interindividual Regulation of the Breast Cancer Resistance Protein/ABCG2 Transporter in Term Human Placentas
      Kristin M. Bircsak, Jamie E. Moscovitz, Xia Wen, Faith Archer, Poi Yu Sofia Yuen, Moiz Mohammed, Naureen Memon, Barry I. Weinberger, Laura M. Saba, Anna M. Vetrano and Lauren M. Aleksunes
      Drug Metabolism and Disposition May 2018, 46 (5) 619-627; DOI: https://doi.org/10.1124/dmd.117.079228
  2. Saigusa, Daisuke

    1. You have access
      Liver Zonation Index of Drug Transporter and Metabolizing Enzyme Protein Expressions in Mouse Liver Acinus
      Masanori Tachikawa, Yuna Sumiyoshiya, Daisuke Saigusa, Kazunari Sasaki, Michitoshi Watanabe, Yasuo Uchida and Tetsuya Terasaki
      Drug Metabolism and Disposition May 2018, 46 (5) 610-618; DOI: https://doi.org/10.1124/dmd.117.079244
  3. Sakai, Tatsuya

    1. You have access
      Interindividual Differences in the Expression of ATP-Binding Cassette and Solute Carrier Family Transporters in Human Skin: DNA Methylation Regulates Transcriptional Activity of the Human ABCC3 Gene
      Tomoki Takechi, Takeshi Hirota, Tatsuya Sakai, Natsumi Maeda, Daisuke Kobayashi and Ichiro Ieiri
      Drug Metabolism and Disposition May 2018, 46 (5) 628-635; DOI: https://doi.org/10.1124/dmd.117.079061
  4. Sarkaria, Jann N.

    1. You have access
      Brain Distribution of a Novel MEK Inhibitor E6201: Implications in the Treatment of Melanoma Brain Metastases
      Gautham Gampa, Minjee Kim, Nicholas Cook-Rostie, Janice K. Laramy, Jann N. Sarkaria, Linda Paradiso, Louis DePalatis and William F. Elmquist
      Drug Metabolism and Disposition May 2018, 46 (5) 658-666; DOI: https://doi.org/10.1124/dmd.117.079194
  5. Sasaki, Kazunari

    1. You have access
      Liver Zonation Index of Drug Transporter and Metabolizing Enzyme Protein Expressions in Mouse Liver Acinus
      Masanori Tachikawa, Yuna Sumiyoshiya, Daisuke Saigusa, Kazunari Sasaki, Michitoshi Watanabe, Yasuo Uchida and Tetsuya Terasaki
      Drug Metabolism and Disposition May 2018, 46 (5) 610-618; DOI: https://doi.org/10.1124/dmd.117.079244
  6. Sato, Masanobu

    1. You have access
      Physiologically Based Pharmacokinetic Modeling of Bosentan Identifies the Saturable Hepatic Uptake As a Major Contributor to Its Nonlinear Pharmacokinetics
      Masanobu Sato, Kota Toshimoto, Atsuko Tomaru, Takashi Yoshikado, Yuta Tanaka, Akihiro Hisaka, Wooin Lee and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2018, 46 (5) 740-748; DOI: https://doi.org/10.1124/dmd.117.078972
  7. Schuetz, Erin G.

    1. You have access
      Beyond Competitive Inhibition: Regulation of ABC Transporters by Kinases and Protein-Protein Interactions as Potential Mechanisms of Drug-Drug Interactions
      Rebecca R. Crawford, Praveen K. Potukuchi, Erin G. Schuetz and John D. Schuetz
      Drug Metabolism and Disposition May 2018, 46 (5) 567-580; DOI: https://doi.org/10.1124/dmd.118.080663
  8. Schuetz, John D.

    1. You have access
      Beyond Competitive Inhibition: Regulation of ABC Transporters by Kinases and Protein-Protein Interactions as Potential Mechanisms of Drug-Drug Interactions
      Rebecca R. Crawford, Praveen K. Potukuchi, Erin G. Schuetz and John D. Schuetz
      Drug Metabolism and Disposition May 2018, 46 (5) 567-580; DOI: https://doi.org/10.1124/dmd.118.080663
  9. Schwarz, Ute I.

    1. You have access
      Apixaban and Rosuvas­­tatin Pharmacokinetics in Nonalcoholic Fatty Liver Disease
      Rommel G. Tirona, Zahra Kassam, Ruth Strapp, Mala Ramu, Catherine Zhu, Melissa Liu, Ute I. Schwarz, Richard B. Kim, Bandar Al-Judaibi and Melanie D. Beaton
      Drug Metabolism and Disposition May 2018, 46 (5) 485-492; DOI: https://doi.org/10.1124/dmd.117.079624
  10. Shah, Vishal

    1. You have access
      Metabolism and Disposition of Verinurad, a Uric Acid Reabsorption Inhibitor, in Humans
      Caroline A. Lee, Chun Yang, Vishal Shah, Zancong Shen, David M. Wilson, Traci M. Ostertag, Jean-Luc Girardet, Jesse Hall and Michael Gillen
      Drug Metabolism and Disposition May 2018, 46 (5) 532-541; DOI: https://doi.org/10.1124/dmd.117.078220
  11. Shan, Mangting

    1. You have access
      Generation and Characterization of a CYP2C11-Null Rat Model by Using the CRISPR/Cas9 Method
      Yuan Wei, Li Yang, Xiaoyan Zhang, Danjuan Sui, Changsuo Wang, Kai Wang, Mangting Shan, Dayong Guo and Hongyu Wang
      Drug Metabolism and Disposition May 2018, 46 (5) 525-531; DOI: https://doi.org/10.1124/dmd.117.078444
  12. Shen, Danny D.

    1. You have access
      Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation
      Dan-Dan Tian, Joshua J. Kellogg, Neşe Okut, Nicholas H. Oberlies, Nadja B. Cech, Danny D. Shen, Jeannine S. McCune and Mary F. Paine
      Drug Metabolism and Disposition May 2018, 46 (5) 552-560; DOI: https://doi.org/10.1124/dmd.117.079491
  13. Shen, Zancong

    1. You have access
      Metabolism and Disposition of Verinurad, a Uric Acid Reabsorption Inhibitor, in Humans
      Caroline A. Lee, Chun Yang, Vishal Shah, Zancong Shen, David M. Wilson, Traci M. Ostertag, Jean-Luc Girardet, Jesse Hall and Michael Gillen
      Drug Metabolism and Disposition May 2018, 46 (5) 532-541; DOI: https://doi.org/10.1124/dmd.117.078220
  14. Shiomi, Susumu

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
  15. Slitt, Angela L.

    1. You have access
      Physiological Regulation of Drug Metabolism and Transport: Pregnancy, Microbiome, Inflammation, Infection, and Fasting
      Edward T. Morgan, Joseph L. Dempsey, Sylvie M. Mimche, Tracey J. Lamb, Supriya Kulkarni, Julia Yue Cui, Hyunyoung Jeong and Angela L. Slitt
      Drug Metabolism and Disposition May 2018, 46 (5) 503-513; DOI: https://doi.org/10.1124/dmd.117.079905
  16. Smith, Robin

    1. You have access
      Rare Variants in the ABCG2 Promoter Modulate In Vivo Activity
      Rachel J. Eclov, Mee J. Kim, Robin Smith, Nadav Ahituv and Deanna L. Kroetz
      Drug Metabolism and Disposition May 2018, 46 (5) 636-642; DOI: https://doi.org/10.1124/dmd.117.079541
  17. Snoeys, Jan

    1. You have access
      MRP2 Inhibition by HIV Protease Inhibitors in Rat and Human Hepatocytes: A Quantitative Confocal Microscopy Study
      Nico Holmstock, Marlies Oorts, Jan Snoeys and Pieter Annaert
      Drug Metabolism and Disposition May 2018, 46 (5) 697-703; DOI: https://doi.org/10.1124/dmd.117.079467
  18. Strapp, Ruth

    1. You have access
      Apixaban and Rosuvas­­tatin Pharmacokinetics in Nonalcoholic Fatty Liver Disease
      Rommel G. Tirona, Zahra Kassam, Ruth Strapp, Mala Ramu, Catherine Zhu, Melissa Liu, Ute I. Schwarz, Richard B. Kim, Bandar Al-Judaibi and Melanie D. Beaton
      Drug Metabolism and Disposition May 2018, 46 (5) 485-492; DOI: https://doi.org/10.1124/dmd.117.079624
  19. Sugiyama, Yuichi

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
    2. You have access
      Organic Anion Transporting Polypeptide 1a4 is Responsible for the Hepatic Uptake of Cardiac Glycosides in Mice
      Junichi Takano, Kazuya Maeda, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2018, 46 (5) 652-657; DOI: https://doi.org/10.1124/dmd.117.079483
    3. You have access
      Evaluation of Alteration in Hepatic and Intestinal BCRP Function In Vivo from ABCG2 c.421C>A Polymorphism Based on PBPK Analysis of Rosuvastatin
      Azusa Futatsugi, Kota Toshimoto, Takashi Yoshikado, Yuichi Sugiyama and Yukio Kato
      Drug Metabolism and Disposition May 2018, 46 (5) 749-757; DOI: https://doi.org/10.1124/dmd.117.078816
    4. You have access
      Physiologically Based Pharmacokinetic Modeling of Bosentan Identifies the Saturable Hepatic Uptake As a Major Contributor to Its Nonlinear Pharmacokinetics
      Masanobu Sato, Kota Toshimoto, Atsuko Tomaru, Takashi Yoshikado, Yuta Tanaka, Akihiro Hisaka, Wooin Lee and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2018, 46 (5) 740-748; DOI: https://doi.org/10.1124/dmd.117.078972
  20. Sui, Danjuan

    1. You have access
      Generation and Characterization of a CYP2C11-Null Rat Model by Using the CRISPR/Cas9 Method
      Yuan Wei, Li Yang, Xiaoyan Zhang, Danjuan Sui, Changsuo Wang, Kai Wang, Mangting Shan, Dayong Guo and Hongyu Wang
      Drug Metabolism and Disposition May 2018, 46 (5) 525-531; DOI: https://doi.org/10.1124/dmd.117.078444
  21. Sumiyoshiya, Yuna

    1. You have access
      Liver Zonation Index of Drug Transporter and Metabolizing Enzyme Protein Expressions in Mouse Liver Acinus
      Masanori Tachikawa, Yuna Sumiyoshiya, Daisuke Saigusa, Kazunari Sasaki, Michitoshi Watanabe, Yasuo Uchida and Tetsuya Terasaki
      Drug Metabolism and Disposition May 2018, 46 (5) 610-618; DOI: https://doi.org/10.1124/dmd.117.079244

T

  1. Tachikawa, Masanori

    1. You have access
      Liver Zonation Index of Drug Transporter and Metabolizing Enzyme Protein Expressions in Mouse Liver Acinus
      Masanori Tachikawa, Yuna Sumiyoshiya, Daisuke Saigusa, Kazunari Sasaki, Michitoshi Watanabe, Yasuo Uchida and Tetsuya Terasaki
      Drug Metabolism and Disposition May 2018, 46 (5) 610-618; DOI: https://doi.org/10.1124/dmd.117.079244
  2. Takano, Junichi

    1. You have access
      Organic Anion Transporting Polypeptide 1a4 is Responsible for the Hepatic Uptake of Cardiac Glycosides in Mice
      Junichi Takano, Kazuya Maeda, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2018, 46 (5) 652-657; DOI: https://doi.org/10.1124/dmd.117.079483
  3. Takechi, Tomoki

    1. You have access
      Interindividual Differences in the Expression of ATP-Binding Cassette and Solute Carrier Family Transporters in Human Skin: DNA Methylation Regulates Transcriptional Activity of the Human ABCC3 Gene
      Tomoki Takechi, Takeshi Hirota, Tatsuya Sakai, Natsumi Maeda, Daisuke Kobayashi and Ichiro Ieiri
      Drug Metabolism and Disposition May 2018, 46 (5) 628-635; DOI: https://doi.org/10.1124/dmd.117.079061
  4. Tamai, Ikumi

    1. You have access
      Sandwich-Cultured Hepatocytes for Mechanistic Understanding of Hepatic Disposition of Parent Drugs and Metabolites by Transporter–Enzyme Interplay
      Norikazu Matsunaga, Yukina Fukuchi, Haruo Imawaka and Ikumi Tamai
      Drug Metabolism and Disposition May 2018, 46 (5) 680-691; DOI: https://doi.org/10.1124/dmd.117.079236
  5. Tanaka, Masaaki

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
  6. Tanaka, Yuta

    1. You have access
      Physiologically Based Pharmacokinetic Modeling of Bosentan Identifies the Saturable Hepatic Uptake As a Major Contributor to Its Nonlinear Pharmacokinetics
      Masanobu Sato, Kota Toshimoto, Atsuko Tomaru, Takashi Yoshikado, Yuta Tanaka, Akihiro Hisaka, Wooin Lee and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2018, 46 (5) 740-748; DOI: https://doi.org/10.1124/dmd.117.078972
  7. Tavraz, Neslihan N.

    1. Open Access
      Expression of Organic Anion Transporter 1 or 3 in Human Kidney Proximal Tubule Cells Reduces Cisplatin Sensitivity
      Tom T. G. Nieskens, Janny G. P. Peters, Dina Dabaghie, Daphne Korte, Katja Jansen, Alexander H. Van Asbeck, Neslihan N. Tavraz, Thomas Friedrich, Frans G. M. Russel, Rosalinde Masereeuw and Martijn J. Wilmer
      Drug Metabolism and Disposition May 2018, 46 (5) 592-599; DOI: https://doi.org/10.1124/dmd.117.079384
  8. Terasaki, Tetsuya

    1. You have access
      Liver Zonation Index of Drug Transporter and Metabolizing Enzyme Protein Expressions in Mouse Liver Acinus
      Masanori Tachikawa, Yuna Sumiyoshiya, Daisuke Saigusa, Kazunari Sasaki, Michitoshi Watanabe, Yasuo Uchida and Tetsuya Terasaki
      Drug Metabolism and Disposition May 2018, 46 (5) 610-618; DOI: https://doi.org/10.1124/dmd.117.079244
  9. Thummel, Kenneth E.

    1. You have access
      Hepatic Transport of 25-Hydroxyvitamin D3 Conjugates: A Mechanism of 25-Hydroxyvitamin D3 Delivery to the Intestinal Tract
      Chunying Gao, Michael Z. Liao, Lyrialle W. Han, Kenneth E. Thummel and Qingcheng Mao
      Drug Metabolism and Disposition May 2018, 46 (5) 581-591; DOI: https://doi.org/10.1124/dmd.117.078881
  10. Tian, Dan-Dan

    1. You have access
      Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation
      Dan-Dan Tian, Joshua J. Kellogg, Neşe Okut, Nicholas H. Oberlies, Nadja B. Cech, Danny D. Shen, Jeannine S. McCune and Mary F. Paine
      Drug Metabolism and Disposition May 2018, 46 (5) 552-560; DOI: https://doi.org/10.1124/dmd.117.079491
  11. Tirona, Rommel G.

    1. You have access
      Apixaban and Rosuvas­­tatin Pharmacokinetics in Nonalcoholic Fatty Liver Disease
      Rommel G. Tirona, Zahra Kassam, Ruth Strapp, Mala Ramu, Catherine Zhu, Melissa Liu, Ute I. Schwarz, Richard B. Kim, Bandar Al-Judaibi and Melanie D. Beaton
      Drug Metabolism and Disposition May 2018, 46 (5) 485-492; DOI: https://doi.org/10.1124/dmd.117.079624
  12. Tomaru, Atsuko

    1. You have access
      Physiologically Based Pharmacokinetic Modeling of Bosentan Identifies the Saturable Hepatic Uptake As a Major Contributor to Its Nonlinear Pharmacokinetics
      Masanobu Sato, Kota Toshimoto, Atsuko Tomaru, Takashi Yoshikado, Yuta Tanaka, Akihiro Hisaka, Wooin Lee and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2018, 46 (5) 740-748; DOI: https://doi.org/10.1124/dmd.117.078972
  13. Toshimoto, Kota

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
    2. You have access
      Evaluation of Alteration in Hepatic and Intestinal BCRP Function In Vivo from ABCG2 c.421C>A Polymorphism Based on PBPK Analysis of Rosuvastatin
      Azusa Futatsugi, Kota Toshimoto, Takashi Yoshikado, Yuichi Sugiyama and Yukio Kato
      Drug Metabolism and Disposition May 2018, 46 (5) 749-757; DOI: https://doi.org/10.1124/dmd.117.078816
    3. You have access
      Physiologically Based Pharmacokinetic Modeling of Bosentan Identifies the Saturable Hepatic Uptake As a Major Contributor to Its Nonlinear Pharmacokinetics
      Masanobu Sato, Kota Toshimoto, Atsuko Tomaru, Takashi Yoshikado, Yuta Tanaka, Akihiro Hisaka, Wooin Lee and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2018, 46 (5) 740-748; DOI: https://doi.org/10.1124/dmd.117.078972
  14. Tseng, Elaine

    1. You have access
      Biosynthesis and Identification of Metabolites of Maraviroc and Their Use in Experiments to Delineate the Relative Contributions of Cytochrome P4503A4 versus 3A5
      Elaine Tseng, Gwendolyn D. Fate, Gregory S. Walker, Theunis C. Goosen and R. Scott Obach
      Drug Metabolism and Disposition May 2018, 46 (5) 493-502; DOI: https://doi.org/10.1124/dmd.117.079855

U

  1. Uchida, Yasuo

    1. You have access
      Liver Zonation Index of Drug Transporter and Metabolizing Enzyme Protein Expressions in Mouse Liver Acinus
      Masanori Tachikawa, Yuna Sumiyoshiya, Daisuke Saigusa, Kazunari Sasaki, Michitoshi Watanabe, Yasuo Uchida and Tetsuya Terasaki
      Drug Metabolism and Disposition May 2018, 46 (5) 610-618; DOI: https://doi.org/10.1124/dmd.117.079244

V

  1. Van Asbeck, Alexander H.

    1. Open Access
      Expression of Organic Anion Transporter 1 or 3 in Human Kidney Proximal Tubule Cells Reduces Cisplatin Sensitivity
      Tom T. G. Nieskens, Janny G. P. Peters, Dina Dabaghie, Daphne Korte, Katja Jansen, Alexander H. Van Asbeck, Neslihan N. Tavraz, Thomas Friedrich, Frans G. M. Russel, Rosalinde Masereeuw and Martijn J. Wilmer
      Drug Metabolism and Disposition May 2018, 46 (5) 592-599; DOI: https://doi.org/10.1124/dmd.117.079384
  2. Varma, Manthena V.S.

    1. You have access
      Comparison of Proteomic Quantification Approaches for Hepatic Drug Transporters: Multiplexed Global Quantitation Correlates with Targeted Proteomic Quantitation
      Anna Vildhede, Chuong Nguyen, Brian K. Erickson, Ryan C. Kunz, Richard Jones, Emi Kimoto, Francis Bourbonais, A. David Rodrigues and Manthena V.S. Varma
      Drug Metabolism and Disposition May 2018, 46 (5) 692-696; DOI: https://doi.org/10.1124/dmd.117.079285
  3. Varma, Manthena V. S.

    1. You have access
      Navigating Transporter Sciences in Pharmacokinetics Characterization Using the Extended Clearance Classification System
      Ayman F. El-Kattan and Manthena V. S. Varma
      Drug Metabolism and Disposition May 2018, 46 (5) 729-739; DOI: https://doi.org/10.1124/dmd.117.080044
  4. Vetrano, Anna M.

    1. Interindividual Regulation of the Breast Cancer Resistance Protein/<em>ABCG2</em> Transporter in Term Human Placentas
      You have access
      Interindividual Regulation of the Breast Cancer Resistance Protein/ABCG2 Transporter in Term Human Placentas
      Kristin M. Bircsak, Jamie E. Moscovitz, Xia Wen, Faith Archer, Poi Yu Sofia Yuen, Moiz Mohammed, Naureen Memon, Barry I. Weinberger, Laura M. Saba, Anna M. Vetrano and Lauren M. Aleksunes
      Drug Metabolism and Disposition May 2018, 46 (5) 619-627; DOI: https://doi.org/10.1124/dmd.117.079228
  5. Vildhede, Anna

    1. You have access
      Comparison of Proteomic Quantification Approaches for Hepatic Drug Transporters: Multiplexed Global Quantitation Correlates with Targeted Proteomic Quantitation
      Anna Vildhede, Chuong Nguyen, Brian K. Erickson, Ryan C. Kunz, Richard Jones, Emi Kimoto, Francis Bourbonais, A. David Rodrigues and Manthena V.S. Varma
      Drug Metabolism and Disposition May 2018, 46 (5) 692-696; DOI: https://doi.org/10.1124/dmd.117.079285
  6. Villeneuve, Lyne

    1. Post-transcriptional Regulation of UGT2B10 Hepatic Expression and Activity by Alternative Splicing
      You have access
      Post-transcriptional Regulation of UGT2B10 Hepatic Expression and Activity by Alternative Splicing
      Adrien Labriet, Eric P. Allain, Michèle Rouleau, Yannick Audet-Delage, Lyne Villeneuve and Chantal Guillemette
      Drug Metabolism and Disposition May 2018, 46 (5) 514-524; DOI: https://doi.org/10.1124/dmd.117.079921
  7. Volak, Laurie P.

    1. You have access
      Intravital Multiphoton Microscopy with Fluorescent Bile Salts in Rats as an In Vivo Biomarker for Hepatobiliary Transport Inhibition
      Jennifer Ryan, Ryan E. Morgan, Yuan Chen, Laurie P. Volak, Robert T. Dunn and Kenneth W. Dunn
      Drug Metabolism and Disposition May 2018, 46 (5) 704-718; DOI: https://doi.org/10.1124/dmd.117.079277

W

  1. Wada, Yasuhiro

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
  2. Walker, Gregory S.

    1. You have access
      Biosynthesis and Identification of Metabolites of Maraviroc and Their Use in Experiments to Delineate the Relative Contributions of Cytochrome P4503A4 versus 3A5
      Elaine Tseng, Gwendolyn D. Fate, Gregory S. Walker, Theunis C. Goosen and R. Scott Obach
      Drug Metabolism and Disposition May 2018, 46 (5) 493-502; DOI: https://doi.org/10.1124/dmd.117.079855
  3. Wang, Changsuo

    1. You have access
      Generation and Characterization of a CYP2C11-Null Rat Model by Using the CRISPR/Cas9 Method
      Yuan Wei, Li Yang, Xiaoyan Zhang, Danjuan Sui, Changsuo Wang, Kai Wang, Mangting Shan, Dayong Guo and Hongyu Wang
      Drug Metabolism and Disposition May 2018, 46 (5) 525-531; DOI: https://doi.org/10.1124/dmd.117.078444
  4. Wang, Guangji

    1. You have access
      A Promising Microtubule Inhibitor Deoxypodophyllotoxin Exhibits Better Efficacy to Multidrug-Resistant Breast Cancer than Paclitaxel via Avoiding Efflux Transport
      Xiaojie Zang, Guangji Wang, Qingyun Cai, Xiao Zheng, Jingwei Zhang, Qianying Chen, Baojin Wu, Xiong Zhu, Haiping Hao and Fang Zhou
      Drug Metabolism and Disposition May 2018, 46 (5) 542-551; DOI: https://doi.org/10.1124/dmd.117.079442
  5. Wang, Hongyu

    1. You have access
      Generation and Characterization of a CYP2C11-Null Rat Model by Using the CRISPR/Cas9 Method
      Yuan Wei, Li Yang, Xiaoyan Zhang, Danjuan Sui, Changsuo Wang, Kai Wang, Mangting Shan, Dayong Guo and Hongyu Wang
      Drug Metabolism and Disposition May 2018, 46 (5) 525-531; DOI: https://doi.org/10.1124/dmd.117.078444
  6. Wang, Joanne

    1. You have access
      Drug Transporters in Xenobiotic Disposition and Pharmacokinetic Prediction
      Qingcheng Mao, Yurong Lai and Joanne Wang
      Drug Metabolism and Disposition May 2018, 46 (5) 561-566; DOI: https://doi.org/10.1124/dmd.118.081356
  7. Wang, Kai

    1. You have access
      Generation and Characterization of a CYP2C11-Null Rat Model by Using the CRISPR/Cas9 Method
      Yuan Wei, Li Yang, Xiaoyan Zhang, Danjuan Sui, Changsuo Wang, Kai Wang, Mangting Shan, Dayong Guo and Hongyu Wang
      Drug Metabolism and Disposition May 2018, 46 (5) 525-531; DOI: https://doi.org/10.1124/dmd.117.078444
  8. Wang, Lixue

    1. You have access
      Identification of a NFκB Inhibition Site on the Proximal Promoter Region of Human Organic Anion Transporting Polypeptide 1A2 Coding Gene SLCO1A2
      Zhaojian Xiang, Weike Li, Lixue Wang, Jicai Yi, Kaiwen Chen and Mei Hong
      Drug Metabolism and Disposition May 2018, 46 (5) 643-651; DOI: https://doi.org/10.1124/dmd.117.078832
  9. Watanabe, Michitoshi

    1. You have access
      Liver Zonation Index of Drug Transporter and Metabolizing Enzyme Protein Expressions in Mouse Liver Acinus
      Masanori Tachikawa, Yuna Sumiyoshiya, Daisuke Saigusa, Kazunari Sasaki, Michitoshi Watanabe, Yasuo Uchida and Tetsuya Terasaki
      Drug Metabolism and Disposition May 2018, 46 (5) 610-618; DOI: https://doi.org/10.1124/dmd.117.079244
  10. Watanabe, Yasuyoshi

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
  11. Wei, Yuan

    1. You have access
      Generation and Characterization of a CYP2C11-Null Rat Model by Using the CRISPR/Cas9 Method
      Yuan Wei, Li Yang, Xiaoyan Zhang, Danjuan Sui, Changsuo Wang, Kai Wang, Mangting Shan, Dayong Guo and Hongyu Wang
      Drug Metabolism and Disposition May 2018, 46 (5) 525-531; DOI: https://doi.org/10.1124/dmd.117.078444
  12. Weinberger, Barry I.

    1. Interindividual Regulation of the Breast Cancer Resistance Protein/<em>ABCG2</em> Transporter in Term Human Placentas
      You have access
      Interindividual Regulation of the Breast Cancer Resistance Protein/ABCG2 Transporter in Term Human Placentas
      Kristin M. Bircsak, Jamie E. Moscovitz, Xia Wen, Faith Archer, Poi Yu Sofia Yuen, Moiz Mohammed, Naureen Memon, Barry I. Weinberger, Laura M. Saba, Anna M. Vetrano and Lauren M. Aleksunes
      Drug Metabolism and Disposition May 2018, 46 (5) 619-627; DOI: https://doi.org/10.1124/dmd.117.079228
  13. Wen, Xia

    1. Interindividual Regulation of the Breast Cancer Resistance Protein/<em>ABCG2</em> Transporter in Term Human Placentas
      You have access
      Interindividual Regulation of the Breast Cancer Resistance Protein/ABCG2 Transporter in Term Human Placentas
      Kristin M. Bircsak, Jamie E. Moscovitz, Xia Wen, Faith Archer, Poi Yu Sofia Yuen, Moiz Mohammed, Naureen Memon, Barry I. Weinberger, Laura M. Saba, Anna M. Vetrano and Lauren M. Aleksunes
      Drug Metabolism and Disposition May 2018, 46 (5) 619-627; DOI: https://doi.org/10.1124/dmd.117.079228
  14. Wilmer, Martijn J.

    1. Open Access
      Expression of Organic Anion Transporter 1 or 3 in Human Kidney Proximal Tubule Cells Reduces Cisplatin Sensitivity
      Tom T. G. Nieskens, Janny G. P. Peters, Dina Dabaghie, Daphne Korte, Katja Jansen, Alexander H. Van Asbeck, Neslihan N. Tavraz, Thomas Friedrich, Frans G. M. Russel, Rosalinde Masereeuw and Martijn J. Wilmer
      Drug Metabolism and Disposition May 2018, 46 (5) 592-599; DOI: https://doi.org/10.1124/dmd.117.079384
  15. Wilson, David M.

    1. You have access
      Metabolism and Disposition of Verinurad, a Uric Acid Reabsorption Inhibitor, in Humans
      Caroline A. Lee, Chun Yang, Vishal Shah, Zancong Shen, David M. Wilson, Traci M. Ostertag, Jean-Luc Girardet, Jesse Hall and Michael Gillen
      Drug Metabolism and Disposition May 2018, 46 (5) 532-541; DOI: https://doi.org/10.1124/dmd.117.078220
  16. Wu, Baojin

    1. You have access
      A Promising Microtubule Inhibitor Deoxypodophyllotoxin Exhibits Better Efficacy to Multidrug-Resistant Breast Cancer than Paclitaxel via Avoiding Efflux Transport
      Xiaojie Zang, Guangji Wang, Qingyun Cai, Xiao Zheng, Jingwei Zhang, Qianying Chen, Baojin Wu, Xiong Zhu, Haiping Hao and Fang Zhou
      Drug Metabolism and Disposition May 2018, 46 (5) 542-551; DOI: https://doi.org/10.1124/dmd.117.079442

X

  1. Xiang, Zhaojian

    1. You have access
      Identification of a NFκB Inhibition Site on the Proximal Promoter Region of Human Organic Anion Transporting Polypeptide 1A2 Coding Gene SLCO1A2
      Zhaojian Xiang, Weike Li, Lixue Wang, Jicai Yi, Kaiwen Chen and Mei Hong
      Drug Metabolism and Disposition May 2018, 46 (5) 643-651; DOI: https://doi.org/10.1124/dmd.117.078832

Y

  1. Yamanaga, Takashi

    1. Open Access
      A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
      Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
      Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
  2. Yang, Chun

    1. You have access
      Metabolism and Disposition of Verinurad, a Uric Acid Reabsorption Inhibitor, in Humans
      Caroline A. Lee, Chun Yang, Vishal Shah, Zancong Shen, David M. Wilson, Traci M. Ostertag, Jean-Luc Girardet, Jesse Hall and Michael Gillen
      Drug Metabolism and Disposition May 2018, 46 (5) 532-541; DOI: https://doi.org/10.1124/dmd.117.078220
  3. Yang, Li

    1. You have access
      Generation and Characterization of a CYP2C11-Null Rat Model by Using the CRISPR/Cas9 Method
      Yuan Wei, Li Yang, Xiaoyan Zhang, Danjuan Sui, Changsuo Wang, Kai Wang, Mangting Shan, Dayong Guo and Hongyu Wang
      Drug Metabolism and Disposition May 2018, 46 (5) 525-531; DOI: https://doi.org/10.1124/dmd.117.078444
  4. Yi, Jicai

    1. You have access
      Identification of a NFκB Inhibition Site on the Proximal Promoter Region of Human Organic Anion Transporting Polypeptide 1A2 Coding Gene SLCO1A2
      Zhaojian Xiang, Weike Li, Lixue Wang, Jicai Yi, Kaiwen Chen and Mei Hong
      Drug Metabolism and Disposition May 2018, 46 (5) 643-651; DOI: https://doi.org/10.1124/dmd.117.078832
  5. Yoshikado, Takashi

    1. You have access
      Evaluation of Alteration in Hepatic and Intestinal BCRP Function In Vivo from ABCG2 c.421C>A Polymorphism Based on PBPK Analysis of Rosuvastatin
      Azusa Futatsugi, Kota Toshimoto, Takashi Yoshikado, Yuichi Sugiyama and Yukio Kato
      Drug Metabolism and Disposition May 2018, 46 (5) 749-757; DOI: https://doi.org/10.1124/dmd.117.078816
    2. You have access
      Physiologically Based Pharmacokinetic Modeling of Bosentan Identifies the Saturable Hepatic Uptake As a Major Contributor to Its Nonlinear Pharmacokinetics
      Masanobu Sato, Kota Toshimoto, Atsuko Tomaru, Takashi Yoshikado, Yuta Tanaka, Akihiro Hisaka, Wooin Lee and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2018, 46 (5) 740-748; DOI: https://doi.org/10.1124/dmd.117.078972
  6. Yuen, Poi Yu Sofia

    1. Interindividual Regulation of the Breast Cancer Resistance Protein/<em>ABCG2</em> Transporter in Term Human Placentas
      You have access
      Interindividual Regulation of the Breast Cancer Resistance Protein/ABCG2 Transporter in Term Human Placentas
      Kristin M. Bircsak, Jamie E. Moscovitz, Xia Wen, Faith Archer, Poi Yu Sofia Yuen, Moiz Mohammed, Naureen Memon, Barry I. Weinberger, Laura M. Saba, Anna M. Vetrano and Lauren M. Aleksunes
      Drug Metabolism and Disposition May 2018, 46 (5) 619-627; DOI: https://doi.org/10.1124/dmd.117.079228

Z

  1. Zang, Xiaojie

    1. You have access
      A Promising Microtubule Inhibitor Deoxypodophyllotoxin Exhibits Better Efficacy to Multidrug-Resistant Breast Cancer than Paclitaxel via Avoiding Efflux Transport
      Xiaojie Zang, Guangji Wang, Qingyun Cai, Xiao Zheng, Jingwei Zhang, Qianying Chen, Baojin Wu, Xiong Zhu, Haiping Hao and Fang Zhou
      Drug Metabolism and Disposition May 2018, 46 (5) 542-551; DOI: https://doi.org/10.1124/dmd.117.079442
  2. Zhang, Jingwei

    1. You have access
      A Promising Microtubule Inhibitor Deoxypodophyllotoxin Exhibits Better Efficacy to Multidrug-Resistant Breast Cancer than Paclitaxel via Avoiding Efflux Transport
      Xiaojie Zang, Guangji Wang, Qingyun Cai, Xiao Zheng, Jingwei Zhang, Qianying Chen, Baojin Wu, Xiong Zhu, Haiping Hao and Fang Zhou
      Drug Metabolism and Disposition May 2018, 46 (5) 542-551; DOI: https://doi.org/10.1124/dmd.117.079442
  3. Zhang, Xiaoyan

    1. You have access
      Generation and Characterization of a CYP2C11-Null Rat Model by Using the CRISPR/Cas9 Method
      Yuan Wei, Li Yang, Xiaoyan Zhang, Danjuan Sui, Changsuo Wang, Kai Wang, Mangting Shan, Dayong Guo and Hongyu Wang
      Drug Metabolism and Disposition May 2018, 46 (5) 525-531; DOI: https://doi.org/10.1124/dmd.117.078444
  4. Zheng, Xiao

    1. You have access
      A Promising Microtubule Inhibitor Deoxypodophyllotoxin Exhibits Better Efficacy to Multidrug-Resistant Breast Cancer than Paclitaxel via Avoiding Efflux Transport
      Xiaojie Zang, Guangji Wang, Qingyun Cai, Xiao Zheng, Jingwei Zhang, Qianying Chen, Baojin Wu, Xiong Zhu, Haiping Hao and Fang Zhou
      Drug Metabolism and Disposition May 2018, 46 (5) 542-551; DOI: https://doi.org/10.1124/dmd.117.079442
  5. Zhou, Fang

    1. You have access
      A Promising Microtubule Inhibitor Deoxypodophyllotoxin Exhibits Better Efficacy to Multidrug-Resistant Breast Cancer than Paclitaxel via Avoiding Efflux Transport
      Xiaojie Zang, Guangji Wang, Qingyun Cai, Xiao Zheng, Jingwei Zhang, Qianying Chen, Baojin Wu, Xiong Zhu, Haiping Hao and Fang Zhou
      Drug Metabolism and Disposition May 2018, 46 (5) 542-551; DOI: https://doi.org/10.1124/dmd.117.079442
  6. Zhu, Catherine

    1. You have access
      Apixaban and Rosuvas­­tatin Pharmacokinetics in Nonalcoholic Fatty Liver Disease
      Rommel G. Tirona, Zahra Kassam, Ruth Strapp, Mala Ramu, Catherine Zhu, Melissa Liu, Ute I. Schwarz, Richard B. Kim, Bandar Al-Judaibi and Melanie D. Beaton
      Drug Metabolism and Disposition May 2018, 46 (5) 485-492; DOI: https://doi.org/10.1124/dmd.117.079624
  7. Zhu, Xiong

    1. You have access
      A Promising Microtubule Inhibitor Deoxypodophyllotoxin Exhibits Better Efficacy to Multidrug-Resistant Breast Cancer than Paclitaxel via Avoiding Efflux Transport
      Xiaojie Zang, Guangji Wang, Qingyun Cai, Xiao Zheng, Jingwei Zhang, Qianying Chen, Baojin Wu, Xiong Zhu, Haiping Hao and Fang Zhou
      Drug Metabolism and Disposition May 2018, 46 (5) 542-551; DOI: https://doi.org/10.1124/dmd.117.079442
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Drug Metabolism and Disposition: 46 (5)
Drug Metabolism and Disposition
Vol. 46, Issue 5
1 May 2018
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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