Table of Contents

Articles

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  N-Methylation of BI 187004 by Thiol S-Methyltransferase

  Hlaing H. Maw, Xingzhong Zeng, Scot Campbell, Mitchell E. Taub and Aaron M. Teitelbaum

  Drug Metabolism and Disposition June 2018, 46 (6) 770-778; DOI: https://doi.org/10.1124/dmd.117.079764
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  Substrate Selectivity Check of the Ergothioneine Transporter

  Julia Tschirka, Madlen Kreisor, Janina Betz and Dirk Gründemann

  Drug Metabolism and Disposition June 2018, 46 (6) 779-785; DOI: https://doi.org/10.1124/dmd.118.080440
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  Activation of 5-HT_1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat Liver

  Ewa Bromek, Marta Rysz, Anna Haduch, Jacek Wójcikowski and Władysława A. Daniel

  Drug Metabolism and Disposition June 2018, 46 (6) 786-793; DOI: https://doi.org/10.1124/dmd.117.079632
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  Structural Studies of Multidrug Resistance Protein 1 Using “Almost” Cysless Template

  Daria N. Trofimova and Roger G. Deeley

  Drug Metabolism and Disposition June 2018, 46 (6) 794-804; DOI: https://doi.org/10.1124/dmd.117.078709
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  Formation of Both Heme and Apoprotein Adducts Contributes to the Mechanism-Based Inactivation of Human CYP2J2 by 17α-Ethynylestradiol

  Hsia-lien Lin, Haoming Zhang and Paul F. Hollenberg

  Drug Metabolism and Disposition June 2018, 46 (6) 813-822; DOI: https://doi.org/10.1124/dmd.118.080903
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  Pharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis Management

  Nating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan Li

  Drug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
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  Refinement of In Vitro Methods for Identification of Aldehyde Oxidase Substrates Reveals Metabolites of Kinase Inhibitors

  Ryan A. Dick

  Drug Metabolism and Disposition June 2018, 46 (6) 846-859; DOI: https://doi.org/10.1124/dmd.118.080960
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  New Pioglitazone Metabolites and Absence of Opened-Ring Metabolites in New N-Substituted Thiazolidinedione

  Michel Leandro Campos, Letícia Bonancio Cerqueira, Bruna Cristina Ulian Silva, Taísa Busaranho Franchin, Marina Rocha Galdino-Pitta, Ivan Rocha Pitta, Rosângela Gonçalves Peccinini and Roberto Pontarolo

  Drug Metabolism and Disposition June 2018, 46 (6) 879-887; DOI: https://doi.org/10.1124/dmd.117.079012
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  Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex

  Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat Prasad

  Drug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
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  Predicting Antitumor Effect of Deoxypodophyllotoxin in NCI-H460 Tumor-Bearing Mice on the Basis of In Vitro Pharmacodynamics and a Physiologically Based Pharmacokinetic-Pharmacodynamic Model

  Yang Chen, Kaijing Zhao, Fei Liu, Ying Li, Zeyu Zhong, Shijin Hong, Xiaodong Liu and Li Liu

  Drug Metabolism and Disposition June 2018, 46 (6) 897-907; DOI: https://doi.org/10.1124/dmd.117.079830
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  Effect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo Models

  Gabriela Dovrtelova, Ondrej Zendulka, Kristyna Noskova, Jan Jurica, Ondrej Pes, Jan Dusek, Alejandro Carazo, Iveta Zapletalova, Natasa Hlavacova and Petr Pavek

  Drug Metabolism and Disposition June 2018, 46 (6) 913-923; DOI: https://doi.org/10.1124/dmd.117.079582