Index by author
June 01, 2018; Volume 46,Issue 6
A
Achour, Brahim
- You have accessData Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5′-Diphosphate–Glucuronosyltransferase Enzymes with Reference to Catalytic ActivityBrahim Achour, Alyssa Dantonio, Mark Niosi, Jonathan J. Novak, Zubida M. Al-Majdoub, Theunis C. Goosen, Amin Rostami-Hodjegan and Jill BarberDrug Metabolism and Disposition June 2018, 46 (6) 805-812; DOI: https://doi.org/10.1124/dmd.117.079475
Al-Majdoub, Zubida M.
- You have accessData Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5′-Diphosphate–Glucuronosyltransferase Enzymes with Reference to Catalytic ActivityBrahim Achour, Alyssa Dantonio, Mark Niosi, Jonathan J. Novak, Zubida M. Al-Majdoub, Theunis C. Goosen, Amin Rostami-Hodjegan and Jill BarberDrug Metabolism and Disposition June 2018, 46 (6) 805-812; DOI: https://doi.org/10.1124/dmd.117.079475
Amory, John K.
- You have accessHepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and SexDeepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat PrasadDrug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
B
Baillie, Thomas A.
- You have accessSafety Assessment of Acyl Glucuronides—A Simplified ParadigmDennis A. Smith, Timothy Hammond and Thomas A. BaillieDrug Metabolism and Disposition June 2018, 46 (6) 908-912; DOI: https://doi.org/10.1124/dmd.118.080515
Barber, Jill
- You have accessData Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5′-Diphosphate–Glucuronosyltransferase Enzymes with Reference to Catalytic ActivityBrahim Achour, Alyssa Dantonio, Mark Niosi, Jonathan J. Novak, Zubida M. Al-Majdoub, Theunis C. Goosen, Amin Rostami-Hodjegan and Jill BarberDrug Metabolism and Disposition June 2018, 46 (6) 805-812; DOI: https://doi.org/10.1124/dmd.117.079475
Basit, Abdul
- You have accessHepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and SexDeepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat PrasadDrug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
Betz, Janina
- You have accessSubstrate Selectivity Check of the Ergothioneine TransporterJulia Tschirka, Madlen Kreisor, Janina Betz and Dirk GründemannDrug Metabolism and Disposition June 2018, 46 (6) 779-785; DOI: https://doi.org/10.1124/dmd.118.080440
Bhatt, Deepak Kumar
- You have accessHepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and SexDeepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat PrasadDrug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
Bister, Bojan
- You have accessA Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott ObachDrug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
Broeckel, Ulrich
- You have accessHepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and SexDeepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat PrasadDrug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
Bromek, Ewa
- You have accessActivation of 5-HT1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat LiverEwa Bromek, Marta Rysz, Anna Haduch, Jacek Wójcikowski and Władysława A. DanielDrug Metabolism and Disposition June 2018, 46 (6) 786-793; DOI: https://doi.org/10.1124/dmd.117.079632
C
Campbell, Scot
- You have accessN-Methylation of BI 187004 by Thiol S-MethyltransferaseHlaing H. Maw, Xingzhong Zeng, Scot Campbell, Mitchell E. Taub and Aaron M. TeitelbaumDrug Metabolism and Disposition June 2018, 46 (6) 770-778; DOI: https://doi.org/10.1124/dmd.117.079764
Campos, Michel Leandro
- You have accessNew Pioglitazone Metabolites and Absence of Opened-Ring Metabolites in New N-Substituted ThiazolidinedioneMichel Leandro Campos, Letícia Bonancio Cerqueira, Bruna Cristina Ulian Silva, Taísa Busaranho Franchin, Marina Rocha Galdino-Pitta, Ivan Rocha Pitta, Rosângela Gonçalves Peccinini and Roberto PontaroloDrug Metabolism and Disposition June 2018, 46 (6) 879-887; DOI: https://doi.org/10.1124/dmd.117.079012
Carazo, Alejandro
- You have accessEffect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo ModelsGabriela Dovrtelova, Ondrej Zendulka, Kristyna Noskova, Jan Jurica, Ondrej Pes, Jan Dusek, Alejandro Carazo, Iveta Zapletalova, Natasa Hlavacova and Petr PavekDrug Metabolism and Disposition June 2018, 46 (6) 913-923; DOI: https://doi.org/10.1124/dmd.117.079582
Cerqueira, Letícia Bonancio
- You have accessNew Pioglitazone Metabolites and Absence of Opened-Ring Metabolites in New N-Substituted ThiazolidinedioneMichel Leandro Campos, Letícia Bonancio Cerqueira, Bruna Cristina Ulian Silva, Taísa Busaranho Franchin, Marina Rocha Galdino-Pitta, Ivan Rocha Pitta, Rosângela Gonçalves Peccinini and Roberto PontaroloDrug Metabolism and Disposition June 2018, 46 (6) 879-887; DOI: https://doi.org/10.1124/dmd.117.079012
Chaudhry, Amarjit Singh
- You have accessHepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and SexDeepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat PrasadDrug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
Chen, Shih-Heng
- You have accessSulfotransferase 4A1 Increases Its Expression in Mouse Neurons as They MatureTakuyu Hashiguchi, Sawako Shindo, Shih-Heng Chen, Jau-Shyong Hong and Masahiko NegishiDrug Metabolism and Disposition June 2018, 46 (6) 860-864; DOI: https://doi.org/10.1124/dmd.118.080838
Chen, Yang
- You have accessPredicting Antitumor Effect of Deoxypodophyllotoxin in NCI-H460 Tumor-Bearing Mice on the Basis of In Vitro Pharmacodynamics and a Physiologically Based Pharmacokinetic-Pharmacodynamic ModelYang Chen, Kaijing Zhao, Fei Liu, Ying Li, Zeyu Zhong, Shijin Hong, Xiaodong Liu and Li LiuDrug Metabolism and Disposition June 2018, 46 (6) 897-907; DOI: https://doi.org/10.1124/dmd.117.079830
Cheng, Chen
- You have accessPharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis ManagementNating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan LiDrug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
Chowdhury, Swapan K.
- You have accessA Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott ObachDrug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
Claw, Katrina G.
- You have accessHepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and SexDeepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat PrasadDrug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
D
Daniel, Władysława A.
- You have accessActivation of 5-HT1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat LiverEwa Bromek, Marta Rysz, Anna Haduch, Jacek Wójcikowski and Władysława A. DanielDrug Metabolism and Disposition June 2018, 46 (6) 786-793; DOI: https://doi.org/10.1124/dmd.117.079632
Dantonio, Alyssa
- You have accessData Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5′-Diphosphate–Glucuronosyltransferase Enzymes with Reference to Catalytic ActivityBrahim Achour, Alyssa Dantonio, Mark Niosi, Jonathan J. Novak, Zubida M. Al-Majdoub, Theunis C. Goosen, Amin Rostami-Hodjegan and Jill BarberDrug Metabolism and Disposition June 2018, 46 (6) 805-812; DOI: https://doi.org/10.1124/dmd.117.079475
Deeley, Roger G.
- Open AccessStructural Studies of Multidrug Resistance Protein 1 Using “Almost” Cysless TemplateDaria N. Trofimova and Roger G. DeeleyDrug Metabolism and Disposition June 2018, 46 (6) 794-804; DOI: https://doi.org/10.1124/dmd.117.078709
Dick, Ryan A.
- You have accessRefinement of In Vitro Methods for Identification of Aldehyde Oxidase Substrates Reveals Metabolites of Kinase InhibitorsRyan A. DickDrug Metabolism and Disposition June 2018, 46 (6) 846-859; DOI: https://doi.org/10.1124/dmd.118.080960
Dovrtelova, Gabriela
- You have accessEffect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo ModelsGabriela Dovrtelova, Ondrej Zendulka, Kristyna Noskova, Jan Jurica, Ondrej Pes, Jan Dusek, Alejandro Carazo, Iveta Zapletalova, Natasa Hlavacova and Petr PavekDrug Metabolism and Disposition June 2018, 46 (6) 913-923; DOI: https://doi.org/10.1124/dmd.117.079582
Du, Feifei
- You have accessPharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis ManagementNating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan LiDrug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
Dusek, Jan
- You have accessEffect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo ModelsGabriela Dovrtelova, Ondrej Zendulka, Kristyna Noskova, Jan Jurica, Ondrej Pes, Jan Dusek, Alejandro Carazo, Iveta Zapletalova, Natasa Hlavacova and Petr PavekDrug Metabolism and Disposition June 2018, 46 (6) 913-923; DOI: https://doi.org/10.1124/dmd.117.079582
F
Franchin, Taísa Busaranho
- You have accessNew Pioglitazone Metabolites and Absence of Opened-Ring Metabolites in New N-Substituted ThiazolidinedioneMichel Leandro Campos, Letícia Bonancio Cerqueira, Bruna Cristina Ulian Silva, Taísa Busaranho Franchin, Marina Rocha Galdino-Pitta, Ivan Rocha Pitta, Rosângela Gonçalves Peccinini and Roberto PontaroloDrug Metabolism and Disposition June 2018, 46 (6) 879-887; DOI: https://doi.org/10.1124/dmd.117.079012
Funk, Christoph
- You have accessA Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott ObachDrug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
G
Gaedigk, Andrea
- You have accessHepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and SexDeepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat PrasadDrug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
Gaedigk, Roger
- You have accessHepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and SexDeepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat PrasadDrug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
Galdino-Pitta, Marina Rocha
- You have accessNew Pioglitazone Metabolites and Absence of Opened-Ring Metabolites in New N-Substituted ThiazolidinedioneMichel Leandro Campos, Letícia Bonancio Cerqueira, Bruna Cristina Ulian Silva, Taísa Busaranho Franchin, Marina Rocha Galdino-Pitta, Ivan Rocha Pitta, Rosângela Gonçalves Peccinini and Roberto PontaroloDrug Metabolism and Disposition June 2018, 46 (6) 879-887; DOI: https://doi.org/10.1124/dmd.117.079012
Goosen, Theunis C.
- You have accessData Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5′-Diphosphate–Glucuronosyltransferase Enzymes with Reference to Catalytic ActivityBrahim Achour, Alyssa Dantonio, Mark Niosi, Jonathan J. Novak, Zubida M. Al-Majdoub, Theunis C. Goosen, Amin Rostami-Hodjegan and Jill BarberDrug Metabolism and Disposition June 2018, 46 (6) 805-812; DOI: https://doi.org/10.1124/dmd.117.079475
Gründemann, Dirk
- You have accessSubstrate Selectivity Check of the Ergothioneine TransporterJulia Tschirka, Madlen Kreisor, Janina Betz and Dirk GründemannDrug Metabolism and Disposition June 2018, 46 (6) 779-785; DOI: https://doi.org/10.1124/dmd.118.080440
H
Haduch, Anna
- You have accessActivation of 5-HT1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat LiverEwa Bromek, Marta Rysz, Anna Haduch, Jacek Wójcikowski and Władysława A. DanielDrug Metabolism and Disposition June 2018, 46 (6) 786-793; DOI: https://doi.org/10.1124/dmd.117.079632
Hammond, Timothy
- You have accessSafety Assessment of Acyl Glucuronides—A Simplified ParadigmDennis A. Smith, Timothy Hammond and Thomas A. BaillieDrug Metabolism and Disposition June 2018, 46 (6) 908-912; DOI: https://doi.org/10.1124/dmd.118.080515
Hashiguchi, Takuyu
- You have accessSulfotransferase 4A1 Increases Its Expression in Mouse Neurons as They MatureTakuyu Hashiguchi, Sawako Shindo, Shih-Heng Chen, Jau-Shyong Hong and Masahiko NegishiDrug Metabolism and Disposition June 2018, 46 (6) 860-864; DOI: https://doi.org/10.1124/dmd.118.080838
Hlavacova, Natasa
- You have accessEffect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo ModelsGabriela Dovrtelova, Ondrej Zendulka, Kristyna Noskova, Jan Jurica, Ondrej Pes, Jan Dusek, Alejandro Carazo, Iveta Zapletalova, Natasa Hlavacova and Petr PavekDrug Metabolism and Disposition June 2018, 46 (6) 913-923; DOI: https://doi.org/10.1124/dmd.117.079582
Hollenberg, Paul F.
- You have accessFormation of Both Heme and Apoprotein Adducts Contributes to the Mechanism-Based Inactivation of Human CYP2J2 by 17α-EthynylestradiolHsia-lien Lin, Haoming Zhang and Paul F. HollenbergDrug Metabolism and Disposition June 2018, 46 (6) 813-822; DOI: https://doi.org/10.1124/dmd.118.080903
Hong, Jau-Shyong
- You have accessSulfotransferase 4A1 Increases Its Expression in Mouse Neurons as They MatureTakuyu Hashiguchi, Sawako Shindo, Shih-Heng Chen, Jau-Shyong Hong and Masahiko NegishiDrug Metabolism and Disposition June 2018, 46 (6) 860-864; DOI: https://doi.org/10.1124/dmd.118.080838
Hong, Shijin
- You have accessPredicting Antitumor Effect of Deoxypodophyllotoxin in NCI-H460 Tumor-Bearing Mice on the Basis of In Vitro Pharmacodynamics and a Physiologically Based Pharmacokinetic-Pharmacodynamic ModelYang Chen, Kaijing Zhao, Fei Liu, Ying Li, Zeyu Zhong, Shijin Hong, Xiaodong Liu and Li LiuDrug Metabolism and Disposition June 2018, 46 (6) 897-907; DOI: https://doi.org/10.1124/dmd.117.079830
Hop, Cornelis E. C. A.
- You have accessA Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott ObachDrug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
Huang, Yühong
- You have accessPharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis ManagementNating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan LiDrug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
Humphreys, W. Griffith
- You have accessA Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott ObachDrug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
I
Igarashi, Fumihiko
- You have accessA Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott ObachDrug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
J
James, Alexander D.
- You have accessA Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott ObachDrug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
Jurica, Jan
- You have accessEffect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo ModelsGabriela Dovrtelova, Ondrej Zendulka, Kristyna Noskova, Jan Jurica, Ondrej Pes, Jan Dusek, Alejandro Carazo, Iveta Zapletalova, Natasa Hlavacova and Petr PavekDrug Metabolism and Disposition June 2018, 46 (6) 913-923; DOI: https://doi.org/10.1124/dmd.117.079582
K
Kagan, Mark
- You have accessA Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott ObachDrug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
Khojasteh, S. Cyrus
- You have accessA Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott ObachDrug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
Kreisor, Madlen
- You have accessSubstrate Selectivity Check of the Ergothioneine TransporterJulia Tschirka, Madlen Kreisor, Janina Betz and Dirk GründemannDrug Metabolism and Disposition June 2018, 46 (6) 779-785; DOI: https://doi.org/10.1124/dmd.118.080440
L
Lee, Seung-been
- You have accessHepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and SexDeepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat PrasadDrug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
Leeder, J. Steven
- You have accessHepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and SexDeepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat PrasadDrug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
Levy, René H.
- You have accessRisk of Clinically Relevant Pharmacokinetic-Based Drug-Drug Interactions with Drugs Approved by the U.S. Food and Drug Administration Between 2013 and 2016Jingjing Yu, Zhu Zhou, Jessica Tay-Sontheimer, René H. Levy and Isabelle Ragueneau-MajlessiDrug Metabolism and Disposition June 2018, 46 (6) 835-845; DOI: https://doi.org/10.1124/dmd.117.078691
Li, Chuan
- You have accessPharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis ManagementNating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan LiDrug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
Li, Li
- You have accessPharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis ManagementNating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan LiDrug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
Li, Yanfen
- You have accessPharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis ManagementNating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan LiDrug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
Li, Ying
- You have accessPredicting Antitumor Effect of Deoxypodophyllotoxin in NCI-H460 Tumor-Bearing Mice on the Basis of In Vitro Pharmacodynamics and a Physiologically Based Pharmacokinetic-Pharmacodynamic ModelYang Chen, Kaijing Zhao, Fei Liu, Ying Li, Zeyu Zhong, Shijin Hong, Xiaodong Liu and Li LiuDrug Metabolism and Disposition June 2018, 46 (6) 897-907; DOI: https://doi.org/10.1124/dmd.117.079830
Lin, Hsia-lien
- You have accessFormation of Both Heme and Apoprotein Adducts Contributes to the Mechanism-Based Inactivation of Human CYP2J2 by 17α-EthynylestradiolHsia-lien Lin, Haoming Zhang and Paul F. HollenbergDrug Metabolism and Disposition June 2018, 46 (6) 813-822; DOI: https://doi.org/10.1124/dmd.118.080903
Liu, Fei
- You have accessPredicting Antitumor Effect of Deoxypodophyllotoxin in NCI-H460 Tumor-Bearing Mice on the Basis of In Vitro Pharmacodynamics and a Physiologically Based Pharmacokinetic-Pharmacodynamic ModelYang Chen, Kaijing Zhao, Fei Liu, Ying Li, Zeyu Zhong, Shijin Hong, Xiaodong Liu and Li LiuDrug Metabolism and Disposition June 2018, 46 (6) 897-907; DOI: https://doi.org/10.1124/dmd.117.079830
Liu, Li
- You have accessPredicting Antitumor Effect of Deoxypodophyllotoxin in NCI-H460 Tumor-Bearing Mice on the Basis of In Vitro Pharmacodynamics and a Physiologically Based Pharmacokinetic-Pharmacodynamic ModelYang Chen, Kaijing Zhao, Fei Liu, Ying Li, Zeyu Zhong, Shijin Hong, Xiaodong Liu and Li LiuDrug Metabolism and Disposition June 2018, 46 (6) 897-907; DOI: https://doi.org/10.1124/dmd.117.079830
Liu, Xiaodong
- You have accessPredicting Antitumor Effect of Deoxypodophyllotoxin in NCI-H460 Tumor-Bearing Mice on the Basis of In Vitro Pharmacodynamics and a Physiologically Based Pharmacokinetic-Pharmacodynamic ModelYang Chen, Kaijing Zhao, Fei Liu, Ying Li, Zeyu Zhong, Shijin Hong, Xiaodong Liu and Li LiuDrug Metabolism and Disposition June 2018, 46 (6) 897-907; DOI: https://doi.org/10.1124/dmd.117.079830
M
Maw, Hlaing H.
- You have accessN-Methylation of BI 187004 by Thiol S-MethyltransferaseHlaing H. Maw, Xingzhong Zeng, Scot Campbell, Mitchell E. Taub and Aaron M. TeitelbaumDrug Metabolism and Disposition June 2018, 46 (6) 770-778; DOI: https://doi.org/10.1124/dmd.117.079764
Mehrotra, Aanchal
- You have accessHepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and SexDeepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat PrasadDrug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
N
Nedderman, Angus N. R.
- You have accessA Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott ObachDrug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
Negishi, Masahiko
- You have accessSulfotransferase 4A1 Increases Its Expression in Mouse Neurons as They MatureTakuyu Hashiguchi, Sawako Shindo, Shih-Heng Chen, Jau-Shyong Hong and Masahiko NegishiDrug Metabolism and Disposition June 2018, 46 (6) 860-864; DOI: https://doi.org/10.1124/dmd.118.080838
Nickerson, Deborah A.
- You have accessHepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and SexDeepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat PrasadDrug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
Niosi, Mark
- You have accessData Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5′-Diphosphate–Glucuronosyltransferase Enzymes with Reference to Catalytic ActivityBrahim Achour, Alyssa Dantonio, Mark Niosi, Jonathan J. Novak, Zubida M. Al-Majdoub, Theunis C. Goosen, Amin Rostami-Hodjegan and Jill BarberDrug Metabolism and Disposition June 2018, 46 (6) 805-812; DOI: https://doi.org/10.1124/dmd.117.079475
Noskova, Kristyna
- You have accessEffect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo ModelsGabriela Dovrtelova, Ondrej Zendulka, Kristyna Noskova, Jan Jurica, Ondrej Pes, Jan Dusek, Alejandro Carazo, Iveta Zapletalova, Natasa Hlavacova and Petr PavekDrug Metabolism and Disposition June 2018, 46 (6) 913-923; DOI: https://doi.org/10.1124/dmd.117.079582
Novak, Jonathan J.
- You have accessData Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5′-Diphosphate–Glucuronosyltransferase Enzymes with Reference to Catalytic ActivityBrahim Achour, Alyssa Dantonio, Mark Niosi, Jonathan J. Novak, Zubida M. Al-Majdoub, Theunis C. Goosen, Amin Rostami-Hodjegan and Jill BarberDrug Metabolism and Disposition June 2018, 46 (6) 805-812; DOI: https://doi.org/10.1124/dmd.117.079475
O
Obach, R. Scott
- You have accessA Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott ObachDrug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
Olaleye, Olajide E.
- You have accessPharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis ManagementNating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan LiDrug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
P
Pavek, Petr
- You have accessEffect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo ModelsGabriela Dovrtelova, Ondrej Zendulka, Kristyna Noskova, Jan Jurica, Ondrej Pes, Jan Dusek, Alejandro Carazo, Iveta Zapletalova, Natasa Hlavacova and Petr PavekDrug Metabolism and Disposition June 2018, 46 (6) 913-923; DOI: https://doi.org/10.1124/dmd.117.079582
Pearce, Robin E.
- You have accessHepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and SexDeepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat PrasadDrug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
Peccinini, Rosângela Gonçalves
- You have accessNew Pioglitazone Metabolites and Absence of Opened-Ring Metabolites in New N-Substituted ThiazolidinedioneMichel Leandro Campos, Letícia Bonancio Cerqueira, Bruna Cristina Ulian Silva, Taísa Busaranho Franchin, Marina Rocha Galdino-Pitta, Ivan Rocha Pitta, Rosângela Gonçalves Peccinini and Roberto PontaroloDrug Metabolism and Disposition June 2018, 46 (6) 879-887; DOI: https://doi.org/10.1124/dmd.117.079012
Pes, Ondrej
- You have accessEffect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo ModelsGabriela Dovrtelova, Ondrej Zendulka, Kristyna Noskova, Jan Jurica, Ondrej Pes, Jan Dusek, Alejandro Carazo, Iveta Zapletalova, Natasa Hlavacova and Petr PavekDrug Metabolism and Disposition June 2018, 46 (6) 913-923; DOI: https://doi.org/10.1124/dmd.117.079582
Pitta, Ivan Rocha
- You have accessNew Pioglitazone Metabolites and Absence of Opened-Ring Metabolites in New N-Substituted ThiazolidinedioneMichel Leandro Campos, Letícia Bonancio Cerqueira, Bruna Cristina Ulian Silva, Taísa Busaranho Franchin, Marina Rocha Galdino-Pitta, Ivan Rocha Pitta, Rosângela Gonçalves Peccinini and Roberto PontaroloDrug Metabolism and Disposition June 2018, 46 (6) 879-887; DOI: https://doi.org/10.1124/dmd.117.079012
Pontarolo, Roberto
- You have accessNew Pioglitazone Metabolites and Absence of Opened-Ring Metabolites in New N-Substituted ThiazolidinedioneMichel Leandro Campos, Letícia Bonancio Cerqueira, Bruna Cristina Ulian Silva, Taísa Busaranho Franchin, Marina Rocha Galdino-Pitta, Ivan Rocha Pitta, Rosângela Gonçalves Peccinini and Roberto PontaroloDrug Metabolism and Disposition June 2018, 46 (6) 879-887; DOI: https://doi.org/10.1124/dmd.117.079012
Prakash, Chandra
- You have accessA Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott ObachDrug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
Prasad, Bhagwat
- You have accessHepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and SexDeepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat PrasadDrug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
R
Ragueneau-Majlessi, Isabelle
- You have accessRisk of Clinically Relevant Pharmacokinetic-Based Drug-Drug Interactions with Drugs Approved by the U.S. Food and Drug Administration Between 2013 and 2016Jingjing Yu, Zhu Zhou, Jessica Tay-Sontheimer, René H. Levy and Isabelle Ragueneau-MajlessiDrug Metabolism and Disposition June 2018, 46 (6) 835-845; DOI: https://doi.org/10.1124/dmd.117.078691
Rostami-Hodjegan, Amin
- You have accessData Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5′-Diphosphate–Glucuronosyltransferase Enzymes with Reference to Catalytic ActivityBrahim Achour, Alyssa Dantonio, Mark Niosi, Jonathan J. Novak, Zubida M. Al-Majdoub, Theunis C. Goosen, Amin Rostami-Hodjegan and Jill BarberDrug Metabolism and Disposition June 2018, 46 (6) 805-812; DOI: https://doi.org/10.1124/dmd.117.079475
Runge, Frank
- You have accessA Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott ObachDrug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
Rysz, Marta
- You have accessActivation of 5-HT1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat LiverEwa Bromek, Marta Rysz, Anna Haduch, Jacek Wójcikowski and Władysława A. DanielDrug Metabolism and Disposition June 2018, 46 (6) 786-793; DOI: https://doi.org/10.1124/dmd.117.079632
S
Schadt, Simone
- You have accessA Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott ObachDrug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
Scheible, Holger
- You have accessA Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott ObachDrug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
Schuetz, Erin G.
- You have accessHepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and SexDeepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat PrasadDrug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
Shi, Yanhong
- You have accessPharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis ManagementNating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan LiDrug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
Shindo, Sawako
- You have accessSulfotransferase 4A1 Increases Its Expression in Mouse Neurons as They MatureTakuyu Hashiguchi, Sawako Shindo, Shih-Heng Chen, Jau-Shyong Hong and Masahiko NegishiDrug Metabolism and Disposition June 2018, 46 (6) 860-864; DOI: https://doi.org/10.1124/dmd.118.080838
Silva, Bruna Cristina Ulian
- You have accessNew Pioglitazone Metabolites and Absence of Opened-Ring Metabolites in New N-Substituted ThiazolidinedioneMichel Leandro Campos, Letícia Bonancio Cerqueira, Bruna Cristina Ulian Silva, Taísa Busaranho Franchin, Marina Rocha Galdino-Pitta, Ivan Rocha Pitta, Rosângela Gonçalves Peccinini and Roberto PontaroloDrug Metabolism and Disposition June 2018, 46 (6) 879-887; DOI: https://doi.org/10.1124/dmd.117.079012
Smith, Dennis A.
- You have accessSafety Assessment of Acyl Glucuronides—A Simplified ParadigmDennis A. Smith, Timothy Hammond and Thomas A. BaillieDrug Metabolism and Disposition June 2018, 46 (6) 908-912; DOI: https://doi.org/10.1124/dmd.118.080515
Spracklin, Douglas K.
- You have accessA Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott ObachDrug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
Sun, Yan
- You have accessPharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis ManagementNating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan LiDrug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
Swart, Piet
- You have accessA Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott ObachDrug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
T
Taub, Mitchell E.
- You have accessN-Methylation of BI 187004 by Thiol S-MethyltransferaseHlaing H. Maw, Xingzhong Zeng, Scot Campbell, Mitchell E. Taub and Aaron M. TeitelbaumDrug Metabolism and Disposition June 2018, 46 (6) 770-778; DOI: https://doi.org/10.1124/dmd.117.079764
Tay-Sontheimer, Jessica
- You have accessRisk of Clinically Relevant Pharmacokinetic-Based Drug-Drug Interactions with Drugs Approved by the U.S. Food and Drug Administration Between 2013 and 2016Jingjing Yu, Zhu Zhou, Jessica Tay-Sontheimer, René H. Levy and Isabelle Ragueneau-MajlessiDrug Metabolism and Disposition June 2018, 46 (6) 835-845; DOI: https://doi.org/10.1124/dmd.117.078691
Teitelbaum, Aaron M.
- You have accessN-Methylation of BI 187004 by Thiol S-MethyltransferaseHlaing H. Maw, Xingzhong Zeng, Scot Campbell, Mitchell E. Taub and Aaron M. TeitelbaumDrug Metabolism and Disposition June 2018, 46 (6) 770-778; DOI: https://doi.org/10.1124/dmd.117.079764
Thornton, Timothy A.
- You have accessHepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and SexDeepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat PrasadDrug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
Trofimova, Daria N.
- Open AccessStructural Studies of Multidrug Resistance Protein 1 Using “Almost” Cysless TemplateDaria N. Trofimova and Roger G. DeeleyDrug Metabolism and Disposition June 2018, 46 (6) 794-804; DOI: https://doi.org/10.1124/dmd.117.078709
Tschirka, Julia
- You have accessSubstrate Selectivity Check of the Ergothioneine TransporterJulia Tschirka, Madlen Kreisor, Janina Betz and Dirk GründemannDrug Metabolism and Disposition June 2018, 46 (6) 779-785; DOI: https://doi.org/10.1124/dmd.118.080440
Tse, Susanna
- You have accessA Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott ObachDrug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
W
Wang, Fengqing
- You have accessPharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis ManagementNating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan LiDrug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
Wen, Qi
- You have accessPharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis ManagementNating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan LiDrug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
Wójcikowski, Jacek
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Xu, Fang
- You have accessPharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis ManagementNating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan LiDrug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
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Yang, Junling
- You have accessPharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis ManagementNating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan LiDrug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
Yu, Jingjing
- You have accessRisk of Clinically Relevant Pharmacokinetic-Based Drug-Drug Interactions with Drugs Approved by the U.S. Food and Drug Administration Between 2013 and 2016Jingjing Yu, Zhu Zhou, Jessica Tay-Sontheimer, René H. Levy and Isabelle Ragueneau-MajlessiDrug Metabolism and Disposition June 2018, 46 (6) 835-845; DOI: https://doi.org/10.1124/dmd.117.078691
Yuan, Josh
- You have accessA Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott ObachDrug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
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Zapletalova, Iveta
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Zendulka, Ondrej
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Zeng, Xingzhong
- You have accessN-Methylation of BI 187004 by Thiol S-MethyltransferaseHlaing H. Maw, Xingzhong Zeng, Scot Campbell, Mitchell E. Taub and Aaron M. TeitelbaumDrug Metabolism and Disposition June 2018, 46 (6) 770-778; DOI: https://doi.org/10.1124/dmd.117.079764
Zhang, Haeyoung
- You have accessHepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and SexDeepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat PrasadDrug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
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- You have accessFormation of Both Heme and Apoprotein Adducts Contributes to the Mechanism-Based Inactivation of Human CYP2J2 by 17α-EthynylestradiolHsia-lien Lin, Haoming Zhang and Paul F. HollenbergDrug Metabolism and Disposition June 2018, 46 (6) 813-822; DOI: https://doi.org/10.1124/dmd.118.080903
Zhang, Naixia
- You have accessPharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis ManagementNating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan LiDrug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
Zhang, Nating
- You have accessPharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis ManagementNating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan LiDrug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
Zhao, Kaijing
- You have accessPredicting Antitumor Effect of Deoxypodophyllotoxin in NCI-H460 Tumor-Bearing Mice on the Basis of In Vitro Pharmacodynamics and a Physiologically Based Pharmacokinetic-Pharmacodynamic ModelYang Chen, Kaijing Zhao, Fei Liu, Ying Li, Zeyu Zhong, Shijin Hong, Xiaodong Liu and Li LiuDrug Metabolism and Disposition June 2018, 46 (6) 897-907; DOI: https://doi.org/10.1124/dmd.117.079830
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- You have accessPredicting Antitumor Effect of Deoxypodophyllotoxin in NCI-H460 Tumor-Bearing Mice on the Basis of In Vitro Pharmacodynamics and a Physiologically Based Pharmacokinetic-Pharmacodynamic ModelYang Chen, Kaijing Zhao, Fei Liu, Ying Li, Zeyu Zhong, Shijin Hong, Xiaodong Liu and Li LiuDrug Metabolism and Disposition June 2018, 46 (6) 897-907; DOI: https://doi.org/10.1124/dmd.117.079830
Zhou, Zhu
- You have accessRisk of Clinically Relevant Pharmacokinetic-Based Drug-Drug Interactions with Drugs Approved by the U.S. Food and Drug Administration Between 2013 and 2016Jingjing Yu, Zhu Zhou, Jessica Tay-Sontheimer, René H. Levy and Isabelle Ragueneau-MajlessiDrug Metabolism and Disposition June 2018, 46 (6) 835-845; DOI: https://doi.org/10.1124/dmd.117.078691
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