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Drug Metabolism & Disposition

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  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
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Index by author

June 01, 2018; Volume 46,Issue 6
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Achour, Brahim

    1. You have access
      Data Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5′-Diphosphate–Glucuronosyltransferase Enzymes with Reference to Catalytic Activity
      Brahim Achour, Alyssa Dantonio, Mark Niosi, Jonathan J. Novak, Zubida M. Al-Majdoub, Theunis C. Goosen, Amin Rostami-Hodjegan and Jill Barber
      Drug Metabolism and Disposition June 2018, 46 (6) 805-812; DOI: https://doi.org/10.1124/dmd.117.079475
  2. Al-Majdoub, Zubida M.

    1. You have access
      Data Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5′-Diphosphate–Glucuronosyltransferase Enzymes with Reference to Catalytic Activity
      Brahim Achour, Alyssa Dantonio, Mark Niosi, Jonathan J. Novak, Zubida M. Al-Majdoub, Theunis C. Goosen, Amin Rostami-Hodjegan and Jill Barber
      Drug Metabolism and Disposition June 2018, 46 (6) 805-812; DOI: https://doi.org/10.1124/dmd.117.079475
  3. Amory, John K.

    1. You have access
      Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex
      Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952

B

  1. Baillie, Thomas A.

    1. You have access
      Safety Assessment of Acyl Glucuronides—A Simplified Paradigm
      Dennis A. Smith, Timothy Hammond and Thomas A. Baillie
      Drug Metabolism and Disposition June 2018, 46 (6) 908-912; DOI: https://doi.org/10.1124/dmd.118.080515
  2. Barber, Jill

    1. You have access
      Data Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5′-Diphosphate–Glucuronosyltransferase Enzymes with Reference to Catalytic Activity
      Brahim Achour, Alyssa Dantonio, Mark Niosi, Jonathan J. Novak, Zubida M. Al-Majdoub, Theunis C. Goosen, Amin Rostami-Hodjegan and Jill Barber
      Drug Metabolism and Disposition June 2018, 46 (6) 805-812; DOI: https://doi.org/10.1124/dmd.117.079475
  3. Basit, Abdul

    1. You have access
      Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex
      Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
  4. Betz, Janina

    1. You have access
      Substrate Selectivity Check of the Ergothioneine Transporter
      Julia Tschirka, Madlen Kreisor, Janina Betz and Dirk Gründemann
      Drug Metabolism and Disposition June 2018, 46 (6) 779-785; DOI: https://doi.org/10.1124/dmd.118.080440
  5. Bhatt, Deepak Kumar

    1. You have access
      Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex
      Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
  6. Bister, Bojan

    1. You have access
      A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
      Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach
      Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
  7. Broeckel, Ulrich

    1. You have access
      Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex
      Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
  8. Bromek, Ewa

    1. You have access
      Activation of 5-HT1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat Liver
      Ewa Bromek, Marta Rysz, Anna Haduch, Jacek Wójcikowski and Władysława A. Daniel
      Drug Metabolism and Disposition June 2018, 46 (6) 786-793; DOI: https://doi.org/10.1124/dmd.117.079632

C

  1. Campbell, Scot

    1. <em>N</em>-Methylation of BI 187004 by Thiol <em>S</em>-Methyltransferase
      You have access
      N-Methylation of BI 187004 by Thiol S-Methyltransferase
      Hlaing H. Maw, Xingzhong Zeng, Scot Campbell, Mitchell E. Taub and Aaron M. Teitelbaum
      Drug Metabolism and Disposition June 2018, 46 (6) 770-778; DOI: https://doi.org/10.1124/dmd.117.079764
  2. Campos, Michel Leandro

    1. You have access
      New Pioglitazone Metabolites and Absence of Opened-Ring Metabolites in New N-Substituted Thiazolidinedione
      Michel Leandro Campos, Letícia Bonancio Cerqueira, Bruna Cristina Ulian Silva, Taísa Busaranho Franchin, Marina Rocha Galdino-Pitta, Ivan Rocha Pitta, Rosângela Gonçalves Peccinini and Roberto Pontarolo
      Drug Metabolism and Disposition June 2018, 46 (6) 879-887; DOI: https://doi.org/10.1124/dmd.117.079012
  3. Carazo, Alejandro

    1. You have access
      Effect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo Models
      Gabriela Dovrtelova, Ondrej Zendulka, Kristyna Noskova, Jan Jurica, Ondrej Pes, Jan Dusek, Alejandro Carazo, Iveta Zapletalova, Natasa Hlavacova and Petr Pavek
      Drug Metabolism and Disposition June 2018, 46 (6) 913-923; DOI: https://doi.org/10.1124/dmd.117.079582
  4. Cerqueira, Letícia Bonancio

    1. You have access
      New Pioglitazone Metabolites and Absence of Opened-Ring Metabolites in New N-Substituted Thiazolidinedione
      Michel Leandro Campos, Letícia Bonancio Cerqueira, Bruna Cristina Ulian Silva, Taísa Busaranho Franchin, Marina Rocha Galdino-Pitta, Ivan Rocha Pitta, Rosângela Gonçalves Peccinini and Roberto Pontarolo
      Drug Metabolism and Disposition June 2018, 46 (6) 879-887; DOI: https://doi.org/10.1124/dmd.117.079012
  5. Chaudhry, Amarjit Singh

    1. You have access
      Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex
      Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
  6. Chen, Shih-Heng

    1. You have access
      Sulfotransferase 4A1 Increases Its Expression in Mouse Neurons as They Mature
      Takuyu Hashiguchi, Sawako Shindo, Shih-Heng Chen, Jau-Shyong Hong and Masahiko Negishi
      Drug Metabolism and Disposition June 2018, 46 (6) 860-864; DOI: https://doi.org/10.1124/dmd.118.080838
  7. Chen, Yang

    1. You have access
      Predicting Antitumor Effect of Deoxypodophyllotoxin in NCI-H460 Tumor-Bearing Mice on the Basis of In Vitro Pharmacodynamics and a Physiologically Based Pharmacokinetic-Pharmacodynamic Model
      Yang Chen, Kaijing Zhao, Fei Liu, Ying Li, Zeyu Zhong, Shijin Hong, Xiaodong Liu and Li Liu
      Drug Metabolism and Disposition June 2018, 46 (6) 897-907; DOI: https://doi.org/10.1124/dmd.117.079830
  8. Cheng, Chen

    1. You have access
      Pharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis Management
      Nating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan Li
      Drug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
  9. Chowdhury, Swapan K.

    1. You have access
      A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
      Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach
      Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
  10. Claw, Katrina G.

    1. You have access
      Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex
      Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952

D

  1. Daniel, Władysława A.

    1. You have access
      Activation of 5-HT1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat Liver
      Ewa Bromek, Marta Rysz, Anna Haduch, Jacek Wójcikowski and Władysława A. Daniel
      Drug Metabolism and Disposition June 2018, 46 (6) 786-793; DOI: https://doi.org/10.1124/dmd.117.079632
  2. Dantonio, Alyssa

    1. You have access
      Data Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5′-Diphosphate–Glucuronosyltransferase Enzymes with Reference to Catalytic Activity
      Brahim Achour, Alyssa Dantonio, Mark Niosi, Jonathan J. Novak, Zubida M. Al-Majdoub, Theunis C. Goosen, Amin Rostami-Hodjegan and Jill Barber
      Drug Metabolism and Disposition June 2018, 46 (6) 805-812; DOI: https://doi.org/10.1124/dmd.117.079475
  3. Deeley, Roger G.

    1. Open Access
      Structural Studies of Multidrug Resistance Protein 1 Using “Almost” Cysless Template
      Daria N. Trofimova and Roger G. Deeley
      Drug Metabolism and Disposition June 2018, 46 (6) 794-804; DOI: https://doi.org/10.1124/dmd.117.078709
  4. Dick, Ryan A.

    1. You have access
      Refinement of In Vitro Methods for Identification of Aldehyde Oxidase Substrates Reveals Metabolites of Kinase Inhibitors
      Ryan A. Dick
      Drug Metabolism and Disposition June 2018, 46 (6) 846-859; DOI: https://doi.org/10.1124/dmd.118.080960
  5. Dovrtelova, Gabriela

    1. You have access
      Effect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo Models
      Gabriela Dovrtelova, Ondrej Zendulka, Kristyna Noskova, Jan Jurica, Ondrej Pes, Jan Dusek, Alejandro Carazo, Iveta Zapletalova, Natasa Hlavacova and Petr Pavek
      Drug Metabolism and Disposition June 2018, 46 (6) 913-923; DOI: https://doi.org/10.1124/dmd.117.079582
  6. Du, Feifei

    1. You have access
      Pharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis Management
      Nating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan Li
      Drug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
  7. Dusek, Jan

    1. You have access
      Effect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo Models
      Gabriela Dovrtelova, Ondrej Zendulka, Kristyna Noskova, Jan Jurica, Ondrej Pes, Jan Dusek, Alejandro Carazo, Iveta Zapletalova, Natasa Hlavacova and Petr Pavek
      Drug Metabolism and Disposition June 2018, 46 (6) 913-923; DOI: https://doi.org/10.1124/dmd.117.079582

F

  1. Franchin, Taísa Busaranho

    1. You have access
      New Pioglitazone Metabolites and Absence of Opened-Ring Metabolites in New N-Substituted Thiazolidinedione
      Michel Leandro Campos, Letícia Bonancio Cerqueira, Bruna Cristina Ulian Silva, Taísa Busaranho Franchin, Marina Rocha Galdino-Pitta, Ivan Rocha Pitta, Rosângela Gonçalves Peccinini and Roberto Pontarolo
      Drug Metabolism and Disposition June 2018, 46 (6) 879-887; DOI: https://doi.org/10.1124/dmd.117.079012
  2. Funk, Christoph

    1. You have access
      A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
      Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach
      Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848

G

  1. Gaedigk, Andrea

    1. You have access
      Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex
      Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
  2. Gaedigk, Roger

    1. You have access
      Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex
      Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
  3. Galdino-Pitta, Marina Rocha

    1. You have access
      New Pioglitazone Metabolites and Absence of Opened-Ring Metabolites in New N-Substituted Thiazolidinedione
      Michel Leandro Campos, Letícia Bonancio Cerqueira, Bruna Cristina Ulian Silva, Taísa Busaranho Franchin, Marina Rocha Galdino-Pitta, Ivan Rocha Pitta, Rosângela Gonçalves Peccinini and Roberto Pontarolo
      Drug Metabolism and Disposition June 2018, 46 (6) 879-887; DOI: https://doi.org/10.1124/dmd.117.079012
  4. Goosen, Theunis C.

    1. You have access
      Data Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5′-Diphosphate–Glucuronosyltransferase Enzymes with Reference to Catalytic Activity
      Brahim Achour, Alyssa Dantonio, Mark Niosi, Jonathan J. Novak, Zubida M. Al-Majdoub, Theunis C. Goosen, Amin Rostami-Hodjegan and Jill Barber
      Drug Metabolism and Disposition June 2018, 46 (6) 805-812; DOI: https://doi.org/10.1124/dmd.117.079475
  5. Gründemann, Dirk

    1. You have access
      Substrate Selectivity Check of the Ergothioneine Transporter
      Julia Tschirka, Madlen Kreisor, Janina Betz and Dirk Gründemann
      Drug Metabolism and Disposition June 2018, 46 (6) 779-785; DOI: https://doi.org/10.1124/dmd.118.080440

H

  1. Haduch, Anna

    1. You have access
      Activation of 5-HT1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat Liver
      Ewa Bromek, Marta Rysz, Anna Haduch, Jacek Wójcikowski and Władysława A. Daniel
      Drug Metabolism and Disposition June 2018, 46 (6) 786-793; DOI: https://doi.org/10.1124/dmd.117.079632
  2. Hammond, Timothy

    1. You have access
      Safety Assessment of Acyl Glucuronides—A Simplified Paradigm
      Dennis A. Smith, Timothy Hammond and Thomas A. Baillie
      Drug Metabolism and Disposition June 2018, 46 (6) 908-912; DOI: https://doi.org/10.1124/dmd.118.080515
  3. Hashiguchi, Takuyu

    1. You have access
      Sulfotransferase 4A1 Increases Its Expression in Mouse Neurons as They Mature
      Takuyu Hashiguchi, Sawako Shindo, Shih-Heng Chen, Jau-Shyong Hong and Masahiko Negishi
      Drug Metabolism and Disposition June 2018, 46 (6) 860-864; DOI: https://doi.org/10.1124/dmd.118.080838
  4. Hlavacova, Natasa

    1. You have access
      Effect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo Models
      Gabriela Dovrtelova, Ondrej Zendulka, Kristyna Noskova, Jan Jurica, Ondrej Pes, Jan Dusek, Alejandro Carazo, Iveta Zapletalova, Natasa Hlavacova and Petr Pavek
      Drug Metabolism and Disposition June 2018, 46 (6) 913-923; DOI: https://doi.org/10.1124/dmd.117.079582
  5. Hollenberg, Paul F.

    1. You have access
      Formation of Both Heme and Apoprotein Adducts Contributes to the Mechanism-Based Inactivation of Human CYP2J2 by 17α-Ethynylestradiol
      Hsia-lien Lin, Haoming Zhang and Paul F. Hollenberg
      Drug Metabolism and Disposition June 2018, 46 (6) 813-822; DOI: https://doi.org/10.1124/dmd.118.080903
  6. Hong, Jau-Shyong

    1. You have access
      Sulfotransferase 4A1 Increases Its Expression in Mouse Neurons as They Mature
      Takuyu Hashiguchi, Sawako Shindo, Shih-Heng Chen, Jau-Shyong Hong and Masahiko Negishi
      Drug Metabolism and Disposition June 2018, 46 (6) 860-864; DOI: https://doi.org/10.1124/dmd.118.080838
  7. Hong, Shijin

    1. You have access
      Predicting Antitumor Effect of Deoxypodophyllotoxin in NCI-H460 Tumor-Bearing Mice on the Basis of In Vitro Pharmacodynamics and a Physiologically Based Pharmacokinetic-Pharmacodynamic Model
      Yang Chen, Kaijing Zhao, Fei Liu, Ying Li, Zeyu Zhong, Shijin Hong, Xiaodong Liu and Li Liu
      Drug Metabolism and Disposition June 2018, 46 (6) 897-907; DOI: https://doi.org/10.1124/dmd.117.079830
  8. Hop, Cornelis E. C. A.

    1. You have access
      A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
      Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach
      Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
  9. Huang, Yühong

    1. You have access
      Pharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis Management
      Nating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan Li
      Drug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
  10. Humphreys, W. Griffith

    1. You have access
      A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
      Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach
      Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848

I

  1. Igarashi, Fumihiko

    1. You have access
      A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
      Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach
      Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848

J

  1. James, Alexander D.

    1. You have access
      A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
      Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach
      Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
  2. Jurica, Jan

    1. You have access
      Effect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo Models
      Gabriela Dovrtelova, Ondrej Zendulka, Kristyna Noskova, Jan Jurica, Ondrej Pes, Jan Dusek, Alejandro Carazo, Iveta Zapletalova, Natasa Hlavacova and Petr Pavek
      Drug Metabolism and Disposition June 2018, 46 (6) 913-923; DOI: https://doi.org/10.1124/dmd.117.079582

K

  1. Kagan, Mark

    1. You have access
      A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
      Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach
      Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
  2. Khojasteh, S. Cyrus

    1. You have access
      A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
      Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach
      Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
  3. Kreisor, Madlen

    1. You have access
      Substrate Selectivity Check of the Ergothioneine Transporter
      Julia Tschirka, Madlen Kreisor, Janina Betz and Dirk Gründemann
      Drug Metabolism and Disposition June 2018, 46 (6) 779-785; DOI: https://doi.org/10.1124/dmd.118.080440

L

  1. Lee, Seung-been

    1. You have access
      Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex
      Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
  2. Leeder, J. Steven

    1. You have access
      Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex
      Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
  3. Levy, René H.

    1. You have access
      Risk of Clinically Relevant Pharmacokinetic-Based Drug-Drug Interactions with Drugs Approved by the U.S. Food and Drug Administration Between 2013 and 2016
      Jingjing Yu, Zhu Zhou, Jessica Tay-Sontheimer, René H. Levy and Isabelle Ragueneau-Majlessi
      Drug Metabolism and Disposition June 2018, 46 (6) 835-845; DOI: https://doi.org/10.1124/dmd.117.078691
  4. Li, Chuan

    1. You have access
      Pharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis Management
      Nating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan Li
      Drug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
  5. Li, Li

    1. You have access
      Pharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis Management
      Nating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan Li
      Drug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
  6. Li, Yanfen

    1. You have access
      Pharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis Management
      Nating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan Li
      Drug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
  7. Li, Ying

    1. You have access
      Predicting Antitumor Effect of Deoxypodophyllotoxin in NCI-H460 Tumor-Bearing Mice on the Basis of In Vitro Pharmacodynamics and a Physiologically Based Pharmacokinetic-Pharmacodynamic Model
      Yang Chen, Kaijing Zhao, Fei Liu, Ying Li, Zeyu Zhong, Shijin Hong, Xiaodong Liu and Li Liu
      Drug Metabolism and Disposition June 2018, 46 (6) 897-907; DOI: https://doi.org/10.1124/dmd.117.079830
  8. Lin, Hsia-lien

    1. You have access
      Formation of Both Heme and Apoprotein Adducts Contributes to the Mechanism-Based Inactivation of Human CYP2J2 by 17α-Ethynylestradiol
      Hsia-lien Lin, Haoming Zhang and Paul F. Hollenberg
      Drug Metabolism and Disposition June 2018, 46 (6) 813-822; DOI: https://doi.org/10.1124/dmd.118.080903
  9. Liu, Fei

    1. You have access
      Predicting Antitumor Effect of Deoxypodophyllotoxin in NCI-H460 Tumor-Bearing Mice on the Basis of In Vitro Pharmacodynamics and a Physiologically Based Pharmacokinetic-Pharmacodynamic Model
      Yang Chen, Kaijing Zhao, Fei Liu, Ying Li, Zeyu Zhong, Shijin Hong, Xiaodong Liu and Li Liu
      Drug Metabolism and Disposition June 2018, 46 (6) 897-907; DOI: https://doi.org/10.1124/dmd.117.079830
  10. Liu, Li

    1. You have access
      Predicting Antitumor Effect of Deoxypodophyllotoxin in NCI-H460 Tumor-Bearing Mice on the Basis of In Vitro Pharmacodynamics and a Physiologically Based Pharmacokinetic-Pharmacodynamic Model
      Yang Chen, Kaijing Zhao, Fei Liu, Ying Li, Zeyu Zhong, Shijin Hong, Xiaodong Liu and Li Liu
      Drug Metabolism and Disposition June 2018, 46 (6) 897-907; DOI: https://doi.org/10.1124/dmd.117.079830
  11. Liu, Xiaodong

    1. You have access
      Predicting Antitumor Effect of Deoxypodophyllotoxin in NCI-H460 Tumor-Bearing Mice on the Basis of In Vitro Pharmacodynamics and a Physiologically Based Pharmacokinetic-Pharmacodynamic Model
      Yang Chen, Kaijing Zhao, Fei Liu, Ying Li, Zeyu Zhong, Shijin Hong, Xiaodong Liu and Li Liu
      Drug Metabolism and Disposition June 2018, 46 (6) 897-907; DOI: https://doi.org/10.1124/dmd.117.079830

M

  1. Maw, Hlaing H.

    1. <em>N</em>-Methylation of BI 187004 by Thiol <em>S</em>-Methyltransferase
      You have access
      N-Methylation of BI 187004 by Thiol S-Methyltransferase
      Hlaing H. Maw, Xingzhong Zeng, Scot Campbell, Mitchell E. Taub and Aaron M. Teitelbaum
      Drug Metabolism and Disposition June 2018, 46 (6) 770-778; DOI: https://doi.org/10.1124/dmd.117.079764
  2. Mehrotra, Aanchal

    1. You have access
      Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex
      Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952

N

  1. Nedderman, Angus N. R.

    1. You have access
      A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
      Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach
      Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
  2. Negishi, Masahiko

    1. You have access
      Sulfotransferase 4A1 Increases Its Expression in Mouse Neurons as They Mature
      Takuyu Hashiguchi, Sawako Shindo, Shih-Heng Chen, Jau-Shyong Hong and Masahiko Negishi
      Drug Metabolism and Disposition June 2018, 46 (6) 860-864; DOI: https://doi.org/10.1124/dmd.118.080838
  3. Nickerson, Deborah A.

    1. You have access
      Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex
      Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
  4. Niosi, Mark

    1. You have access
      Data Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5′-Diphosphate–Glucuronosyltransferase Enzymes with Reference to Catalytic Activity
      Brahim Achour, Alyssa Dantonio, Mark Niosi, Jonathan J. Novak, Zubida M. Al-Majdoub, Theunis C. Goosen, Amin Rostami-Hodjegan and Jill Barber
      Drug Metabolism and Disposition June 2018, 46 (6) 805-812; DOI: https://doi.org/10.1124/dmd.117.079475
  5. Noskova, Kristyna

    1. You have access
      Effect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo Models
      Gabriela Dovrtelova, Ondrej Zendulka, Kristyna Noskova, Jan Jurica, Ondrej Pes, Jan Dusek, Alejandro Carazo, Iveta Zapletalova, Natasa Hlavacova and Petr Pavek
      Drug Metabolism and Disposition June 2018, 46 (6) 913-923; DOI: https://doi.org/10.1124/dmd.117.079582
  6. Novak, Jonathan J.

    1. You have access
      Data Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5′-Diphosphate–Glucuronosyltransferase Enzymes with Reference to Catalytic Activity
      Brahim Achour, Alyssa Dantonio, Mark Niosi, Jonathan J. Novak, Zubida M. Al-Majdoub, Theunis C. Goosen, Amin Rostami-Hodjegan and Jill Barber
      Drug Metabolism and Disposition June 2018, 46 (6) 805-812; DOI: https://doi.org/10.1124/dmd.117.079475

O

  1. Obach, R. Scott

    1. You have access
      A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
      Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach
      Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
  2. Olaleye, Olajide E.

    1. You have access
      Pharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis Management
      Nating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan Li
      Drug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673

P

  1. Pavek, Petr

    1. You have access
      Effect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo Models
      Gabriela Dovrtelova, Ondrej Zendulka, Kristyna Noskova, Jan Jurica, Ondrej Pes, Jan Dusek, Alejandro Carazo, Iveta Zapletalova, Natasa Hlavacova and Petr Pavek
      Drug Metabolism and Disposition June 2018, 46 (6) 913-923; DOI: https://doi.org/10.1124/dmd.117.079582
  2. Pearce, Robin E.

    1. You have access
      Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex
      Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
  3. Peccinini, Rosângela Gonçalves

    1. You have access
      New Pioglitazone Metabolites and Absence of Opened-Ring Metabolites in New N-Substituted Thiazolidinedione
      Michel Leandro Campos, Letícia Bonancio Cerqueira, Bruna Cristina Ulian Silva, Taísa Busaranho Franchin, Marina Rocha Galdino-Pitta, Ivan Rocha Pitta, Rosângela Gonçalves Peccinini and Roberto Pontarolo
      Drug Metabolism and Disposition June 2018, 46 (6) 879-887; DOI: https://doi.org/10.1124/dmd.117.079012
  4. Pes, Ondrej

    1. You have access
      Effect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo Models
      Gabriela Dovrtelova, Ondrej Zendulka, Kristyna Noskova, Jan Jurica, Ondrej Pes, Jan Dusek, Alejandro Carazo, Iveta Zapletalova, Natasa Hlavacova and Petr Pavek
      Drug Metabolism and Disposition June 2018, 46 (6) 913-923; DOI: https://doi.org/10.1124/dmd.117.079582
  5. Pitta, Ivan Rocha

    1. You have access
      New Pioglitazone Metabolites and Absence of Opened-Ring Metabolites in New N-Substituted Thiazolidinedione
      Michel Leandro Campos, Letícia Bonancio Cerqueira, Bruna Cristina Ulian Silva, Taísa Busaranho Franchin, Marina Rocha Galdino-Pitta, Ivan Rocha Pitta, Rosângela Gonçalves Peccinini and Roberto Pontarolo
      Drug Metabolism and Disposition June 2018, 46 (6) 879-887; DOI: https://doi.org/10.1124/dmd.117.079012
  6. Pontarolo, Roberto

    1. You have access
      New Pioglitazone Metabolites and Absence of Opened-Ring Metabolites in New N-Substituted Thiazolidinedione
      Michel Leandro Campos, Letícia Bonancio Cerqueira, Bruna Cristina Ulian Silva, Taísa Busaranho Franchin, Marina Rocha Galdino-Pitta, Ivan Rocha Pitta, Rosângela Gonçalves Peccinini and Roberto Pontarolo
      Drug Metabolism and Disposition June 2018, 46 (6) 879-887; DOI: https://doi.org/10.1124/dmd.117.079012
  7. Prakash, Chandra

    1. You have access
      A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
      Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach
      Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
  8. Prasad, Bhagwat

    1. You have access
      Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex
      Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952

R

  1. Ragueneau-Majlessi, Isabelle

    1. You have access
      Risk of Clinically Relevant Pharmacokinetic-Based Drug-Drug Interactions with Drugs Approved by the U.S. Food and Drug Administration Between 2013 and 2016
      Jingjing Yu, Zhu Zhou, Jessica Tay-Sontheimer, René H. Levy and Isabelle Ragueneau-Majlessi
      Drug Metabolism and Disposition June 2018, 46 (6) 835-845; DOI: https://doi.org/10.1124/dmd.117.078691
  2. Rostami-Hodjegan, Amin

    1. You have access
      Data Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5′-Diphosphate–Glucuronosyltransferase Enzymes with Reference to Catalytic Activity
      Brahim Achour, Alyssa Dantonio, Mark Niosi, Jonathan J. Novak, Zubida M. Al-Majdoub, Theunis C. Goosen, Amin Rostami-Hodjegan and Jill Barber
      Drug Metabolism and Disposition June 2018, 46 (6) 805-812; DOI: https://doi.org/10.1124/dmd.117.079475
  3. Runge, Frank

    1. You have access
      A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
      Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach
      Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
  4. Rysz, Marta

    1. You have access
      Activation of 5-HT1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat Liver
      Ewa Bromek, Marta Rysz, Anna Haduch, Jacek Wójcikowski and Władysława A. Daniel
      Drug Metabolism and Disposition June 2018, 46 (6) 786-793; DOI: https://doi.org/10.1124/dmd.117.079632

S

  1. Schadt, Simone

    1. You have access
      A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
      Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach
      Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
  2. Scheible, Holger

    1. You have access
      A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
      Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach
      Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
  3. Schuetz, Erin G.

    1. You have access
      Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex
      Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
  4. Shi, Yanhong

    1. You have access
      Pharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis Management
      Nating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan Li
      Drug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
  5. Shindo, Sawako

    1. You have access
      Sulfotransferase 4A1 Increases Its Expression in Mouse Neurons as They Mature
      Takuyu Hashiguchi, Sawako Shindo, Shih-Heng Chen, Jau-Shyong Hong and Masahiko Negishi
      Drug Metabolism and Disposition June 2018, 46 (6) 860-864; DOI: https://doi.org/10.1124/dmd.118.080838
  6. Silva, Bruna Cristina Ulian

    1. You have access
      New Pioglitazone Metabolites and Absence of Opened-Ring Metabolites in New N-Substituted Thiazolidinedione
      Michel Leandro Campos, Letícia Bonancio Cerqueira, Bruna Cristina Ulian Silva, Taísa Busaranho Franchin, Marina Rocha Galdino-Pitta, Ivan Rocha Pitta, Rosângela Gonçalves Peccinini and Roberto Pontarolo
      Drug Metabolism and Disposition June 2018, 46 (6) 879-887; DOI: https://doi.org/10.1124/dmd.117.079012
  7. Smith, Dennis A.

    1. You have access
      Safety Assessment of Acyl Glucuronides—A Simplified Paradigm
      Dennis A. Smith, Timothy Hammond and Thomas A. Baillie
      Drug Metabolism and Disposition June 2018, 46 (6) 908-912; DOI: https://doi.org/10.1124/dmd.118.080515
  8. Spracklin, Douglas K.

    1. You have access
      A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
      Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach
      Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
  9. Sun, Yan

    1. You have access
      Pharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis Management
      Nating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan Li
      Drug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
  10. Swart, Piet

    1. You have access
      A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
      Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach
      Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848

T

  1. Taub, Mitchell E.

    1. <em>N</em>-Methylation of BI 187004 by Thiol <em>S</em>-Methyltransferase
      You have access
      N-Methylation of BI 187004 by Thiol S-Methyltransferase
      Hlaing H. Maw, Xingzhong Zeng, Scot Campbell, Mitchell E. Taub and Aaron M. Teitelbaum
      Drug Metabolism and Disposition June 2018, 46 (6) 770-778; DOI: https://doi.org/10.1124/dmd.117.079764
  2. Tay-Sontheimer, Jessica

    1. You have access
      Risk of Clinically Relevant Pharmacokinetic-Based Drug-Drug Interactions with Drugs Approved by the U.S. Food and Drug Administration Between 2013 and 2016
      Jingjing Yu, Zhu Zhou, Jessica Tay-Sontheimer, René H. Levy and Isabelle Ragueneau-Majlessi
      Drug Metabolism and Disposition June 2018, 46 (6) 835-845; DOI: https://doi.org/10.1124/dmd.117.078691
  3. Teitelbaum, Aaron M.

    1. <em>N</em>-Methylation of BI 187004 by Thiol <em>S</em>-Methyltransferase
      You have access
      N-Methylation of BI 187004 by Thiol S-Methyltransferase
      Hlaing H. Maw, Xingzhong Zeng, Scot Campbell, Mitchell E. Taub and Aaron M. Teitelbaum
      Drug Metabolism and Disposition June 2018, 46 (6) 770-778; DOI: https://doi.org/10.1124/dmd.117.079764
  4. Thornton, Timothy A.

    1. You have access
      Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex
      Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
  5. Trofimova, Daria N.

    1. Open Access
      Structural Studies of Multidrug Resistance Protein 1 Using “Almost” Cysless Template
      Daria N. Trofimova and Roger G. Deeley
      Drug Metabolism and Disposition June 2018, 46 (6) 794-804; DOI: https://doi.org/10.1124/dmd.117.078709
  6. Tschirka, Julia

    1. You have access
      Substrate Selectivity Check of the Ergothioneine Transporter
      Julia Tschirka, Madlen Kreisor, Janina Betz and Dirk Gründemann
      Drug Metabolism and Disposition June 2018, 46 (6) 779-785; DOI: https://doi.org/10.1124/dmd.118.080440
  7. Tse, Susanna

    1. You have access
      A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
      Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach
      Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848

W

  1. Wang, Fengqing

    1. You have access
      Pharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis Management
      Nating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan Li
      Drug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
  2. Wen, Qi

    1. You have access
      Pharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis Management
      Nating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan Li
      Drug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
  3. Wójcikowski, Jacek

    1. You have access
      Activation of 5-HT1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat Liver
      Ewa Bromek, Marta Rysz, Anna Haduch, Jacek Wójcikowski and Władysława A. Daniel
      Drug Metabolism and Disposition June 2018, 46 (6) 786-793; DOI: https://doi.org/10.1124/dmd.117.079632

X

  1. Xu, Fang

    1. You have access
      Pharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis Management
      Nating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan Li
      Drug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673

Y

  1. Yang, Junling

    1. You have access
      Pharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis Management
      Nating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan Li
      Drug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
  2. Yu, Jingjing

    1. You have access
      Risk of Clinically Relevant Pharmacokinetic-Based Drug-Drug Interactions with Drugs Approved by the U.S. Food and Drug Administration Between 2013 and 2016
      Jingjing Yu, Zhu Zhou, Jessica Tay-Sontheimer, René H. Levy and Isabelle Ragueneau-Majlessi
      Drug Metabolism and Disposition June 2018, 46 (6) 835-845; DOI: https://doi.org/10.1124/dmd.117.078691
  3. Yuan, Josh

    1. You have access
      A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
      Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach
      Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848

Z

  1. Zapletalova, Iveta

    1. You have access
      Effect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo Models
      Gabriela Dovrtelova, Ondrej Zendulka, Kristyna Noskova, Jan Jurica, Ondrej Pes, Jan Dusek, Alejandro Carazo, Iveta Zapletalova, Natasa Hlavacova and Petr Pavek
      Drug Metabolism and Disposition June 2018, 46 (6) 913-923; DOI: https://doi.org/10.1124/dmd.117.079582
  2. Zendulka, Ondrej

    1. You have access
      Effect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo Models
      Gabriela Dovrtelova, Ondrej Zendulka, Kristyna Noskova, Jan Jurica, Ondrej Pes, Jan Dusek, Alejandro Carazo, Iveta Zapletalova, Natasa Hlavacova and Petr Pavek
      Drug Metabolism and Disposition June 2018, 46 (6) 913-923; DOI: https://doi.org/10.1124/dmd.117.079582
  3. Zeng, Xingzhong

    1. <em>N</em>-Methylation of BI 187004 by Thiol <em>S</em>-Methyltransferase
      You have access
      N-Methylation of BI 187004 by Thiol S-Methyltransferase
      Hlaing H. Maw, Xingzhong Zeng, Scot Campbell, Mitchell E. Taub and Aaron M. Teitelbaum
      Drug Metabolism and Disposition June 2018, 46 (6) 770-778; DOI: https://doi.org/10.1124/dmd.117.079764
  4. Zhang, Haeyoung

    1. You have access
      Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex
      Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder and Bhagwat Prasad
      Drug Metabolism and Disposition June 2018, 46 (6) 888-896; DOI: https://doi.org/10.1124/dmd.118.080952
  5. Zhang, Haoming

    1. You have access
      Formation of Both Heme and Apoprotein Adducts Contributes to the Mechanism-Based Inactivation of Human CYP2J2 by 17α-Ethynylestradiol
      Hsia-lien Lin, Haoming Zhang and Paul F. Hollenberg
      Drug Metabolism and Disposition June 2018, 46 (6) 813-822; DOI: https://doi.org/10.1124/dmd.118.080903
  6. Zhang, Naixia

    1. You have access
      Pharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis Management
      Nating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan Li
      Drug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
  7. Zhang, Nating

    1. You have access
      Pharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis Management
      Nating Zhang, Chen Cheng, Olajide E. Olaleye, Yan Sun, Li Li, Yühong Huang, Feifei Du, Junling Yang, Fengqing Wang, Yanhong Shi, Fang Xu, Yanfen Li, Qi Wen, Naixia Zhang and Chuan Li
      Drug Metabolism and Disposition June 2018, 46 (6) 823-834; DOI: https://doi.org/10.1124/dmd.117.079673
  8. Zhao, Kaijing

    1. You have access
      Predicting Antitumor Effect of Deoxypodophyllotoxin in NCI-H460 Tumor-Bearing Mice on the Basis of In Vitro Pharmacodynamics and a Physiologically Based Pharmacokinetic-Pharmacodynamic Model
      Yang Chen, Kaijing Zhao, Fei Liu, Ying Li, Zeyu Zhong, Shijin Hong, Xiaodong Liu and Li Liu
      Drug Metabolism and Disposition June 2018, 46 (6) 897-907; DOI: https://doi.org/10.1124/dmd.117.079830
  9. Zhong, Zeyu

    1. You have access
      Predicting Antitumor Effect of Deoxypodophyllotoxin in NCI-H460 Tumor-Bearing Mice on the Basis of In Vitro Pharmacodynamics and a Physiologically Based Pharmacokinetic-Pharmacodynamic Model
      Yang Chen, Kaijing Zhao, Fei Liu, Ying Li, Zeyu Zhong, Shijin Hong, Xiaodong Liu and Li Liu
      Drug Metabolism and Disposition June 2018, 46 (6) 897-907; DOI: https://doi.org/10.1124/dmd.117.079830
  10. Zhou, Zhu

    1. You have access
      Risk of Clinically Relevant Pharmacokinetic-Based Drug-Drug Interactions with Drugs Approved by the U.S. Food and Drug Administration Between 2013 and 2016
      Jingjing Yu, Zhu Zhou, Jessica Tay-Sontheimer, René H. Levy and Isabelle Ragueneau-Majlessi
      Drug Metabolism and Disposition June 2018, 46 (6) 835-845; DOI: https://doi.org/10.1124/dmd.117.078691
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Drug Metabolism and Disposition: 46 (6)
Drug Metabolism and Disposition
Vol. 46, Issue 6
1 Jun 2018
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