Quantitative Analysis of Complex Drug-Drug Interactions between Cerivastatin and Metabolism/Transport Inhibitors Using Physiologically Based Pharmacokinetic Modeling

Yoshiaki Yao; Kota Toshimoto; Soo-Jin Kim; Takashi Yoshikado; Yuichi Sugiyama

doi:10.1124/dmd.117.079210

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Quantitative Analysis of Complex Drug-Drug Interactions between Cerivastatin and Metabolism/Transport Inhibitors Using Physiologically Based Pharmacokinetic Modeling

Yoshiaki Yao, Kota Toshimoto, Soo-Jin Kim, Takashi Yoshikado and Yuichi Sugiyama

Drug Metabolism and Disposition July 2018, 46 (7) 924-933; DOI: https://doi.org/10.1124/dmd.117.079210

Yoshiaki Yao

Analysis & Pharmacokinetics Research Laboratories, Drug Discovery Research, Astellas Pharma Inc., Ibaraki, Japan (Y.Y.), and Sugiyama Laboratory, RIKEN Innovation Center, RIKEN, Kanagawa, Japan (K.T., S.K., T.Y., Y.S.)

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Kota Toshimoto

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Soo-Jin Kim

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Takashi Yoshikado

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Yuichi Sugiyama

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Drug Metabolism and Disposition

Vol. 46, Issue 7

1 Jul 2018

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