Index by author
September 01, 2018; Volume 46,Issue 9
A
Ahn, Sojung
- You have accessDisposition of Methamphetamine and Major Metabolites in Mice: Role of Organic Cation Transporter 3 in Tissue-Selective Accumulation of Para-HydroxymethamphetamineDavid J. Wagner, Laura M. Shireman, Sojung Ahn, Danny D. Shen and Joanne WangDrug Metabolism and Disposition September 2018, 46 (9) 1277-1284; DOI: https://doi.org/10.1124/dmd.118.082131
B
Bapiro, Tashinga E.
- You have accessComplete Substrate Inhibition of Cytochrome P450 2C8 by AZD9496, an Oral Selective Estrogen Receptor DegraderTashinga E. Bapiro, Andy Sykes, Scott Martin, Michael Davies, James W. T. Yates, Matthias Hoch, Helen E. Rollison and Barry JonesDrug Metabolism and Disposition September 2018, 46 (9) 1268-1276; DOI: https://doi.org/10.1124/dmd.118.081539
Baptista, Pedro Miguel
- You have accessRecellularized Native Kidney Scaffolds as a Novel Tool in Nephrotoxicity ScreeningMichele Fedecostante, Koen G. C. Westphal, Michele F. Buono, Natalia Sanchez Romero, Martijn J. Wilmer, Janis Kerkering, Pedro Miguel Baptista, Joost G. Hoenderop and Rosalinde MasereeuwDrug Metabolism and Disposition September 2018, 46 (9) 1338-1350; DOI: https://doi.org/10.1124/dmd.118.080721
Buckley, David B.
- Open AccessConsiderations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical RelevanceJane R. Kenny, Diane Ramsden, David B. Buckley, Shannon Dallas, Conrad Fung, Michael Mohutsky, Heidi J. Einolf, Liangfu Chen, Joshua G. Dekeyser, Maria Fitzgerald, Theunis C. Goosen, Y. Amy Siu, Robert L. Walsky, George Zhang, Donald Tweedie and Niresh HariparsadDrug Metabolism and Disposition September 2018, 46 (9) 1285-1303; DOI: https://doi.org/10.1124/dmd.118.081927
Buono, Michele F.
- You have accessRecellularized Native Kidney Scaffolds as a Novel Tool in Nephrotoxicity ScreeningMichele Fedecostante, Koen G. C. Westphal, Michele F. Buono, Natalia Sanchez Romero, Martijn J. Wilmer, Janis Kerkering, Pedro Miguel Baptista, Joost G. Hoenderop and Rosalinde MasereeuwDrug Metabolism and Disposition September 2018, 46 (9) 1338-1350; DOI: https://doi.org/10.1124/dmd.118.080721
C
Cao, Lijuan
- You have accessGlycyrrhizin Alleviates Nonalcoholic Steatohepatitis via Modulating Bile Acids and Meta-InflammationTingting Yan, Hong Wang, Lijuan Cao, Qiong Wang, Shogo Takahashi, Tomoki Yagai, Guolin Li, Kristopher W. Krausz, Guangji Wang, Frank J. Gonzalez and Haiping HaoDrug Metabolism and Disposition September 2018, 46 (9) 1310-1319; DOI: https://doi.org/10.1124/dmd.118.082008
Chen, Liangfu
- Open AccessConsiderations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical RelevanceJane R. Kenny, Diane Ramsden, David B. Buckley, Shannon Dallas, Conrad Fung, Michael Mohutsky, Heidi J. Einolf, Liangfu Chen, Joshua G. Dekeyser, Maria Fitzgerald, Theunis C. Goosen, Y. Amy Siu, Robert L. Walsky, George Zhang, Donald Tweedie and Niresh HariparsadDrug Metabolism and Disposition September 2018, 46 (9) 1285-1303; DOI: https://doi.org/10.1124/dmd.118.081927
Chen, Xiaoyan
- You have accessDifferences in the In Vivo and In Vitro Metabolism of Imrecoxib in Humans: Formation of the Rate-Limiting Aldehyde IntermediateXiangyu Hou, Jialan Zhou, Songda Yu, Lei Zhou, Yifan Zhang, Dafang Zhong and Xiaoyan ChenDrug Metabolism and Disposition September 2018, 46 (9) 1320-1328; DOI: https://doi.org/10.1124/dmd.118.081182
Colclough, Nicola
- You have accessAn Investigation into the Prediction of the Plasma Concentration-Time Profile and Its Interindividual Variability for a Range of Flavin-Containing Monooxygenase Substrates Using a Physiologically Based Pharmacokinetic Modeling ApproachVenkatesh Pilla Reddy, Barry C. Jones, Nicola Colclough, Abhishek Srivastava, Joanne Wilson and Danxi LiDrug Metabolism and Disposition September 2018, 46 (9) 1259-1267; DOI: https://doi.org/10.1124/dmd.118.080648
D
Dallas, Shannon
- Open AccessConsiderations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical RelevanceJane R. Kenny, Diane Ramsden, David B. Buckley, Shannon Dallas, Conrad Fung, Michael Mohutsky, Heidi J. Einolf, Liangfu Chen, Joshua G. Dekeyser, Maria Fitzgerald, Theunis C. Goosen, Y. Amy Siu, Robert L. Walsky, George Zhang, Donald Tweedie and Niresh HariparsadDrug Metabolism and Disposition September 2018, 46 (9) 1285-1303; DOI: https://doi.org/10.1124/dmd.118.081927
Davies, Michael
- You have accessComplete Substrate Inhibition of Cytochrome P450 2C8 by AZD9496, an Oral Selective Estrogen Receptor DegraderTashinga E. Bapiro, Andy Sykes, Scott Martin, Michael Davies, James W. T. Yates, Matthias Hoch, Helen E. Rollison and Barry JonesDrug Metabolism and Disposition September 2018, 46 (9) 1268-1276; DOI: https://doi.org/10.1124/dmd.118.081539
Dekeyser, Joshua G.
- Open AccessConsiderations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical RelevanceJane R. Kenny, Diane Ramsden, David B. Buckley, Shannon Dallas, Conrad Fung, Michael Mohutsky, Heidi J. Einolf, Liangfu Chen, Joshua G. Dekeyser, Maria Fitzgerald, Theunis C. Goosen, Y. Amy Siu, Robert L. Walsky, George Zhang, Donald Tweedie and Niresh HariparsadDrug Metabolism and Disposition September 2018, 46 (9) 1285-1303; DOI: https://doi.org/10.1124/dmd.118.081927
E
Einolf, Heidi J.
- Open AccessConsiderations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical RelevanceJane R. Kenny, Diane Ramsden, David B. Buckley, Shannon Dallas, Conrad Fung, Michael Mohutsky, Heidi J. Einolf, Liangfu Chen, Joshua G. Dekeyser, Maria Fitzgerald, Theunis C. Goosen, Y. Amy Siu, Robert L. Walsky, George Zhang, Donald Tweedie and Niresh HariparsadDrug Metabolism and Disposition September 2018, 46 (9) 1285-1303; DOI: https://doi.org/10.1124/dmd.118.081927
F
Fang, Yan
- You have accessContent and Activities of UGT2B7 in Human Liver In Vitro and Predicted In Vivo: A Bottom-Up ApproachChen Xu, Jie Gao, Hai-Feng Zhang, Na Gao, Yuan-yuan Guo, Yan Fang, Qiang Wen and Hai-Ling QiaoDrug Metabolism and Disposition September 2018, 46 (9) 1351-1359; DOI: https://doi.org/10.1124/dmd.118.082024
Fedecostante, Michele
- You have accessRecellularized Native Kidney Scaffolds as a Novel Tool in Nephrotoxicity ScreeningMichele Fedecostante, Koen G. C. Westphal, Michele F. Buono, Natalia Sanchez Romero, Martijn J. Wilmer, Janis Kerkering, Pedro Miguel Baptista, Joost G. Hoenderop and Rosalinde MasereeuwDrug Metabolism and Disposition September 2018, 46 (9) 1338-1350; DOI: https://doi.org/10.1124/dmd.118.080721
Fitzgerald, Maria
- Open AccessConsiderations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical RelevanceJane R. Kenny, Diane Ramsden, David B. Buckley, Shannon Dallas, Conrad Fung, Michael Mohutsky, Heidi J. Einolf, Liangfu Chen, Joshua G. Dekeyser, Maria Fitzgerald, Theunis C. Goosen, Y. Amy Siu, Robert L. Walsky, George Zhang, Donald Tweedie and Niresh HariparsadDrug Metabolism and Disposition September 2018, 46 (9) 1285-1303; DOI: https://doi.org/10.1124/dmd.118.081927
Fung, Conrad
- Open AccessConsiderations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical RelevanceJane R. Kenny, Diane Ramsden, David B. Buckley, Shannon Dallas, Conrad Fung, Michael Mohutsky, Heidi J. Einolf, Liangfu Chen, Joshua G. Dekeyser, Maria Fitzgerald, Theunis C. Goosen, Y. Amy Siu, Robert L. Walsky, George Zhang, Donald Tweedie and Niresh HariparsadDrug Metabolism and Disposition September 2018, 46 (9) 1285-1303; DOI: https://doi.org/10.1124/dmd.118.081927
G
Gao, Jie
- You have accessContent and Activities of UGT2B7 in Human Liver In Vitro and Predicted In Vivo: A Bottom-Up ApproachChen Xu, Jie Gao, Hai-Feng Zhang, Na Gao, Yuan-yuan Guo, Yan Fang, Qiang Wen and Hai-Ling QiaoDrug Metabolism and Disposition September 2018, 46 (9) 1351-1359; DOI: https://doi.org/10.1124/dmd.118.082024
Gao, Na
- You have accessContent and Activities of UGT2B7 in Human Liver In Vitro and Predicted In Vivo: A Bottom-Up ApproachChen Xu, Jie Gao, Hai-Feng Zhang, Na Gao, Yuan-yuan Guo, Yan Fang, Qiang Wen and Hai-Ling QiaoDrug Metabolism and Disposition September 2018, 46 (9) 1351-1359; DOI: https://doi.org/10.1124/dmd.118.082024
Godamudunage, Malika P.
- You have accessComparison of Antifungal Azole Interactions with Adult Cytochrome P450 3A4 versus Neonatal Cytochrome P450 3A7Malika P. Godamudunage, Anne M. Grech and Emily E. ScottDrug Metabolism and Disposition September 2018, 46 (9) 1329-1337; DOI: https://doi.org/10.1124/dmd.118.082032
Gonzalez, Frank J.
- You have accessGlycyrrhizin Alleviates Nonalcoholic Steatohepatitis via Modulating Bile Acids and Meta-InflammationTingting Yan, Hong Wang, Lijuan Cao, Qiong Wang, Shogo Takahashi, Tomoki Yagai, Guolin Li, Kristopher W. Krausz, Guangji Wang, Frank J. Gonzalez and Haiping HaoDrug Metabolism and Disposition September 2018, 46 (9) 1310-1319; DOI: https://doi.org/10.1124/dmd.118.082008
Goosen, Theunis C.
- Open AccessConsiderations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical RelevanceJane R. Kenny, Diane Ramsden, David B. Buckley, Shannon Dallas, Conrad Fung, Michael Mohutsky, Heidi J. Einolf, Liangfu Chen, Joshua G. Dekeyser, Maria Fitzgerald, Theunis C. Goosen, Y. Amy Siu, Robert L. Walsky, George Zhang, Donald Tweedie and Niresh HariparsadDrug Metabolism and Disposition September 2018, 46 (9) 1285-1303; DOI: https://doi.org/10.1124/dmd.118.081927
Grech, Anne M.
- You have accessComparison of Antifungal Azole Interactions with Adult Cytochrome P450 3A4 versus Neonatal Cytochrome P450 3A7Malika P. Godamudunage, Anne M. Grech and Emily E. ScottDrug Metabolism and Disposition September 2018, 46 (9) 1329-1337; DOI: https://doi.org/10.1124/dmd.118.082032
Guo, Yuan-yuan
- You have accessContent and Activities of UGT2B7 in Human Liver In Vitro and Predicted In Vivo: A Bottom-Up ApproachChen Xu, Jie Gao, Hai-Feng Zhang, Na Gao, Yuan-yuan Guo, Yan Fang, Qiang Wen and Hai-Ling QiaoDrug Metabolism and Disposition September 2018, 46 (9) 1351-1359; DOI: https://doi.org/10.1124/dmd.118.082024
H
Hao, Haiping
- You have accessGlycyrrhizin Alleviates Nonalcoholic Steatohepatitis via Modulating Bile Acids and Meta-InflammationTingting Yan, Hong Wang, Lijuan Cao, Qiong Wang, Shogo Takahashi, Tomoki Yagai, Guolin Li, Kristopher W. Krausz, Guangji Wang, Frank J. Gonzalez and Haiping HaoDrug Metabolism and Disposition September 2018, 46 (9) 1310-1319; DOI: https://doi.org/10.1124/dmd.118.082008
Hariparsad, Niresh
- Open AccessConsiderations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical RelevanceJane R. Kenny, Diane Ramsden, David B. Buckley, Shannon Dallas, Conrad Fung, Michael Mohutsky, Heidi J. Einolf, Liangfu Chen, Joshua G. Dekeyser, Maria Fitzgerald, Theunis C. Goosen, Y. Amy Siu, Robert L. Walsky, George Zhang, Donald Tweedie and Niresh HariparsadDrug Metabolism and Disposition September 2018, 46 (9) 1285-1303; DOI: https://doi.org/10.1124/dmd.118.081927
Hoch, Matthias
- You have accessComplete Substrate Inhibition of Cytochrome P450 2C8 by AZD9496, an Oral Selective Estrogen Receptor DegraderTashinga E. Bapiro, Andy Sykes, Scott Martin, Michael Davies, James W. T. Yates, Matthias Hoch, Helen E. Rollison and Barry JonesDrug Metabolism and Disposition September 2018, 46 (9) 1268-1276; DOI: https://doi.org/10.1124/dmd.118.081539
Hodge, Jessica
- You have accessThe Roles of Xenobiotic Receptors: Beyond Chemical DispositionBryan Mackowiak, Jessica Hodge, Sydney Stern and Hongbing WangDrug Metabolism and Disposition September 2018, 46 (9) 1361-1371; DOI: https://doi.org/10.1124/dmd.118.081042
Hoenderop, Joost G.
- You have accessRecellularized Native Kidney Scaffolds as a Novel Tool in Nephrotoxicity ScreeningMichele Fedecostante, Koen G. C. Westphal, Michele F. Buono, Natalia Sanchez Romero, Martijn J. Wilmer, Janis Kerkering, Pedro Miguel Baptista, Joost G. Hoenderop and Rosalinde MasereeuwDrug Metabolism and Disposition September 2018, 46 (9) 1338-1350; DOI: https://doi.org/10.1124/dmd.118.080721
Hou, Xiangyu
- You have accessDifferences in the In Vivo and In Vitro Metabolism of Imrecoxib in Humans: Formation of the Rate-Limiting Aldehyde IntermediateXiangyu Hou, Jialan Zhou, Songda Yu, Lei Zhou, Yifan Zhang, Dafang Zhong and Xiaoyan ChenDrug Metabolism and Disposition September 2018, 46 (9) 1320-1328; DOI: https://doi.org/10.1124/dmd.118.081182
I
Ishida, Kazuya
- You have accessTransport Kinetics, Selective Inhibition, and Successful Prediction of In Vivo Inhibition of Rat Hepatic Organic Anion Transporting PolypeptidesKazuya Ishida, Mohammed Ullah, Beáta Tóth, Viktoria Juhasz and Jashvant D. UnadkatDrug Metabolism and Disposition September 2018, 46 (9) 1251-1258; DOI: https://doi.org/10.1124/dmd.118.080770
J
Johnson, Cassandra
- You have accessDecreased Kidney Function Is Associated with Enhanced Hepatic Flavin Monooxygenase Activity and Increased Circulating Trimethylamine N-Oxide Concentrations in MiceCassandra Johnson, Alexander J. Prokopienko, Raymond E. West, Thomas D. Nolin and Jason R. StubbsDrug Metabolism and Disposition September 2018, 46 (9) 1304-1309; DOI: https://doi.org/10.1124/dmd.118.081646
Jones, Barry
- You have accessComplete Substrate Inhibition of Cytochrome P450 2C8 by AZD9496, an Oral Selective Estrogen Receptor DegraderTashinga E. Bapiro, Andy Sykes, Scott Martin, Michael Davies, James W. T. Yates, Matthias Hoch, Helen E. Rollison and Barry JonesDrug Metabolism and Disposition September 2018, 46 (9) 1268-1276; DOI: https://doi.org/10.1124/dmd.118.081539
Jones, Barry C.
- You have accessAn Investigation into the Prediction of the Plasma Concentration-Time Profile and Its Interindividual Variability for a Range of Flavin-Containing Monooxygenase Substrates Using a Physiologically Based Pharmacokinetic Modeling ApproachVenkatesh Pilla Reddy, Barry C. Jones, Nicola Colclough, Abhishek Srivastava, Joanne Wilson and Danxi LiDrug Metabolism and Disposition September 2018, 46 (9) 1259-1267; DOI: https://doi.org/10.1124/dmd.118.080648
Juhasz, Viktoria
- You have accessTransport Kinetics, Selective Inhibition, and Successful Prediction of In Vivo Inhibition of Rat Hepatic Organic Anion Transporting PolypeptidesKazuya Ishida, Mohammed Ullah, Beáta Tóth, Viktoria Juhasz and Jashvant D. UnadkatDrug Metabolism and Disposition September 2018, 46 (9) 1251-1258; DOI: https://doi.org/10.1124/dmd.118.080770
K
Kalari, Krishna R.
- You have accessSingle Nucleotide Polymorphisms (SNPs) Distant from Xenobiotic Response Elements Can Modulate Aryl Hydrocarbon Receptor Function: SNP-Dependent CYP1A1 InductionDuan Liu, Sisi Qin, Balmiki Ray, Krishna R. Kalari, Liewei Wang and Richard M. WeinshilboumDrug Metabolism and Disposition September 2018, 46 (9) 1372-1381; DOI: https://doi.org/10.1124/dmd.118.082164
Kenny, Jane R.
- Open AccessConsiderations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical RelevanceJane R. Kenny, Diane Ramsden, David B. Buckley, Shannon Dallas, Conrad Fung, Michael Mohutsky, Heidi J. Einolf, Liangfu Chen, Joshua G. Dekeyser, Maria Fitzgerald, Theunis C. Goosen, Y. Amy Siu, Robert L. Walsky, George Zhang, Donald Tweedie and Niresh HariparsadDrug Metabolism and Disposition September 2018, 46 (9) 1285-1303; DOI: https://doi.org/10.1124/dmd.118.081927
Kerkering, Janis
- You have accessRecellularized Native Kidney Scaffolds as a Novel Tool in Nephrotoxicity ScreeningMichele Fedecostante, Koen G. C. Westphal, Michele F. Buono, Natalia Sanchez Romero, Martijn J. Wilmer, Janis Kerkering, Pedro Miguel Baptista, Joost G. Hoenderop and Rosalinde MasereeuwDrug Metabolism and Disposition September 2018, 46 (9) 1338-1350; DOI: https://doi.org/10.1124/dmd.118.080721
Krausz, Kristopher W.
- You have accessGlycyrrhizin Alleviates Nonalcoholic Steatohepatitis via Modulating Bile Acids and Meta-InflammationTingting Yan, Hong Wang, Lijuan Cao, Qiong Wang, Shogo Takahashi, Tomoki Yagai, Guolin Li, Kristopher W. Krausz, Guangji Wang, Frank J. Gonzalez and Haiping HaoDrug Metabolism and Disposition September 2018, 46 (9) 1310-1319; DOI: https://doi.org/10.1124/dmd.118.082008
L
Li, Danxi
- You have accessAn Investigation into the Prediction of the Plasma Concentration-Time Profile and Its Interindividual Variability for a Range of Flavin-Containing Monooxygenase Substrates Using a Physiologically Based Pharmacokinetic Modeling ApproachVenkatesh Pilla Reddy, Barry C. Jones, Nicola Colclough, Abhishek Srivastava, Joanne Wilson and Danxi LiDrug Metabolism and Disposition September 2018, 46 (9) 1259-1267; DOI: https://doi.org/10.1124/dmd.118.080648
Li, Guolin
- You have accessGlycyrrhizin Alleviates Nonalcoholic Steatohepatitis via Modulating Bile Acids and Meta-InflammationTingting Yan, Hong Wang, Lijuan Cao, Qiong Wang, Shogo Takahashi, Tomoki Yagai, Guolin Li, Kristopher W. Krausz, Guangji Wang, Frank J. Gonzalez and Haiping HaoDrug Metabolism and Disposition September 2018, 46 (9) 1310-1319; DOI: https://doi.org/10.1124/dmd.118.082008
Liu, Duan
- You have accessSingle Nucleotide Polymorphisms (SNPs) Distant from Xenobiotic Response Elements Can Modulate Aryl Hydrocarbon Receptor Function: SNP-Dependent CYP1A1 InductionDuan Liu, Sisi Qin, Balmiki Ray, Krishna R. Kalari, Liewei Wang and Richard M. WeinshilboumDrug Metabolism and Disposition September 2018, 46 (9) 1372-1381; DOI: https://doi.org/10.1124/dmd.118.082164
M
Mackowiak, Bryan
- You have accessThe Roles of Xenobiotic Receptors: Beyond Chemical DispositionBryan Mackowiak, Jessica Hodge, Sydney Stern and Hongbing WangDrug Metabolism and Disposition September 2018, 46 (9) 1361-1371; DOI: https://doi.org/10.1124/dmd.118.081042
Martin, Scott
- You have accessComplete Substrate Inhibition of Cytochrome P450 2C8 by AZD9496, an Oral Selective Estrogen Receptor DegraderTashinga E. Bapiro, Andy Sykes, Scott Martin, Michael Davies, James W. T. Yates, Matthias Hoch, Helen E. Rollison and Barry JonesDrug Metabolism and Disposition September 2018, 46 (9) 1268-1276; DOI: https://doi.org/10.1124/dmd.118.081539
Masereeuw, Rosalinde
- You have accessRecellularized Native Kidney Scaffolds as a Novel Tool in Nephrotoxicity ScreeningMichele Fedecostante, Koen G. C. Westphal, Michele F. Buono, Natalia Sanchez Romero, Martijn J. Wilmer, Janis Kerkering, Pedro Miguel Baptista, Joost G. Hoenderop and Rosalinde MasereeuwDrug Metabolism and Disposition September 2018, 46 (9) 1338-1350; DOI: https://doi.org/10.1124/dmd.118.080721
Mohutsky, Michael
- Open AccessConsiderations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical RelevanceJane R. Kenny, Diane Ramsden, David B. Buckley, Shannon Dallas, Conrad Fung, Michael Mohutsky, Heidi J. Einolf, Liangfu Chen, Joshua G. Dekeyser, Maria Fitzgerald, Theunis C. Goosen, Y. Amy Siu, Robert L. Walsky, George Zhang, Donald Tweedie and Niresh HariparsadDrug Metabolism and Disposition September 2018, 46 (9) 1285-1303; DOI: https://doi.org/10.1124/dmd.118.081927
N
Nolin, Thomas D.
- You have accessDecreased Kidney Function Is Associated with Enhanced Hepatic Flavin Monooxygenase Activity and Increased Circulating Trimethylamine N-Oxide Concentrations in MiceCassandra Johnson, Alexander J. Prokopienko, Raymond E. West, Thomas D. Nolin and Jason R. StubbsDrug Metabolism and Disposition September 2018, 46 (9) 1304-1309; DOI: https://doi.org/10.1124/dmd.118.081646
P
Prokopienko, Alexander J.
- You have accessDecreased Kidney Function Is Associated with Enhanced Hepatic Flavin Monooxygenase Activity and Increased Circulating Trimethylamine N-Oxide Concentrations in MiceCassandra Johnson, Alexander J. Prokopienko, Raymond E. West, Thomas D. Nolin and Jason R. StubbsDrug Metabolism and Disposition September 2018, 46 (9) 1304-1309; DOI: https://doi.org/10.1124/dmd.118.081646
Q
Qiao, Hai-Ling
- You have accessContent and Activities of UGT2B7 in Human Liver In Vitro and Predicted In Vivo: A Bottom-Up ApproachChen Xu, Jie Gao, Hai-Feng Zhang, Na Gao, Yuan-yuan Guo, Yan Fang, Qiang Wen and Hai-Ling QiaoDrug Metabolism and Disposition September 2018, 46 (9) 1351-1359; DOI: https://doi.org/10.1124/dmd.118.082024
Qin, Sisi
- You have accessSingle Nucleotide Polymorphisms (SNPs) Distant from Xenobiotic Response Elements Can Modulate Aryl Hydrocarbon Receptor Function: SNP-Dependent CYP1A1 InductionDuan Liu, Sisi Qin, Balmiki Ray, Krishna R. Kalari, Liewei Wang and Richard M. WeinshilboumDrug Metabolism and Disposition September 2018, 46 (9) 1372-1381; DOI: https://doi.org/10.1124/dmd.118.082164
R
Ramsden, Diane
- Open AccessConsiderations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical RelevanceJane R. Kenny, Diane Ramsden, David B. Buckley, Shannon Dallas, Conrad Fung, Michael Mohutsky, Heidi J. Einolf, Liangfu Chen, Joshua G. Dekeyser, Maria Fitzgerald, Theunis C. Goosen, Y. Amy Siu, Robert L. Walsky, George Zhang, Donald Tweedie and Niresh HariparsadDrug Metabolism and Disposition September 2018, 46 (9) 1285-1303; DOI: https://doi.org/10.1124/dmd.118.081927
Ray, Balmiki
- You have accessSingle Nucleotide Polymorphisms (SNPs) Distant from Xenobiotic Response Elements Can Modulate Aryl Hydrocarbon Receptor Function: SNP-Dependent CYP1A1 InductionDuan Liu, Sisi Qin, Balmiki Ray, Krishna R. Kalari, Liewei Wang and Richard M. WeinshilboumDrug Metabolism and Disposition September 2018, 46 (9) 1372-1381; DOI: https://doi.org/10.1124/dmd.118.082164
Reddy, Venkatesh Pilla
- You have accessAn Investigation into the Prediction of the Plasma Concentration-Time Profile and Its Interindividual Variability for a Range of Flavin-Containing Monooxygenase Substrates Using a Physiologically Based Pharmacokinetic Modeling ApproachVenkatesh Pilla Reddy, Barry C. Jones, Nicola Colclough, Abhishek Srivastava, Joanne Wilson and Danxi LiDrug Metabolism and Disposition September 2018, 46 (9) 1259-1267; DOI: https://doi.org/10.1124/dmd.118.080648
Rollison, Helen E.
- You have accessComplete Substrate Inhibition of Cytochrome P450 2C8 by AZD9496, an Oral Selective Estrogen Receptor DegraderTashinga E. Bapiro, Andy Sykes, Scott Martin, Michael Davies, James W. T. Yates, Matthias Hoch, Helen E. Rollison and Barry JonesDrug Metabolism and Disposition September 2018, 46 (9) 1268-1276; DOI: https://doi.org/10.1124/dmd.118.081539
S
Sanchez Romero, Natalia
- You have accessRecellularized Native Kidney Scaffolds as a Novel Tool in Nephrotoxicity ScreeningMichele Fedecostante, Koen G. C. Westphal, Michele F. Buono, Natalia Sanchez Romero, Martijn J. Wilmer, Janis Kerkering, Pedro Miguel Baptista, Joost G. Hoenderop and Rosalinde MasereeuwDrug Metabolism and Disposition September 2018, 46 (9) 1338-1350; DOI: https://doi.org/10.1124/dmd.118.080721
Scott, Emily E.
- You have accessComparison of Antifungal Azole Interactions with Adult Cytochrome P450 3A4 versus Neonatal Cytochrome P450 3A7Malika P. Godamudunage, Anne M. Grech and Emily E. ScottDrug Metabolism and Disposition September 2018, 46 (9) 1329-1337; DOI: https://doi.org/10.1124/dmd.118.082032
Shen, Danny D.
- You have accessDisposition of Methamphetamine and Major Metabolites in Mice: Role of Organic Cation Transporter 3 in Tissue-Selective Accumulation of Para-HydroxymethamphetamineDavid J. Wagner, Laura M. Shireman, Sojung Ahn, Danny D. Shen and Joanne WangDrug Metabolism and Disposition September 2018, 46 (9) 1277-1284; DOI: https://doi.org/10.1124/dmd.118.082131
Shireman, Laura M.
- You have accessDisposition of Methamphetamine and Major Metabolites in Mice: Role of Organic Cation Transporter 3 in Tissue-Selective Accumulation of Para-HydroxymethamphetamineDavid J. Wagner, Laura M. Shireman, Sojung Ahn, Danny D. Shen and Joanne WangDrug Metabolism and Disposition September 2018, 46 (9) 1277-1284; DOI: https://doi.org/10.1124/dmd.118.082131
Siu, Y. Amy
- Open AccessConsiderations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical RelevanceJane R. Kenny, Diane Ramsden, David B. Buckley, Shannon Dallas, Conrad Fung, Michael Mohutsky, Heidi J. Einolf, Liangfu Chen, Joshua G. Dekeyser, Maria Fitzgerald, Theunis C. Goosen, Y. Amy Siu, Robert L. Walsky, George Zhang, Donald Tweedie and Niresh HariparsadDrug Metabolism and Disposition September 2018, 46 (9) 1285-1303; DOI: https://doi.org/10.1124/dmd.118.081927
Srivastava, Abhishek
- You have accessAn Investigation into the Prediction of the Plasma Concentration-Time Profile and Its Interindividual Variability for a Range of Flavin-Containing Monooxygenase Substrates Using a Physiologically Based Pharmacokinetic Modeling ApproachVenkatesh Pilla Reddy, Barry C. Jones, Nicola Colclough, Abhishek Srivastava, Joanne Wilson and Danxi LiDrug Metabolism and Disposition September 2018, 46 (9) 1259-1267; DOI: https://doi.org/10.1124/dmd.118.080648
Stern, Sydney
- You have accessThe Roles of Xenobiotic Receptors: Beyond Chemical DispositionBryan Mackowiak, Jessica Hodge, Sydney Stern and Hongbing WangDrug Metabolism and Disposition September 2018, 46 (9) 1361-1371; DOI: https://doi.org/10.1124/dmd.118.081042
Stubbs, Jason R.
- You have accessDecreased Kidney Function Is Associated with Enhanced Hepatic Flavin Monooxygenase Activity and Increased Circulating Trimethylamine N-Oxide Concentrations in MiceCassandra Johnson, Alexander J. Prokopienko, Raymond E. West, Thomas D. Nolin and Jason R. StubbsDrug Metabolism and Disposition September 2018, 46 (9) 1304-1309; DOI: https://doi.org/10.1124/dmd.118.081646
Sykes, Andy
- You have accessComplete Substrate Inhibition of Cytochrome P450 2C8 by AZD9496, an Oral Selective Estrogen Receptor DegraderTashinga E. Bapiro, Andy Sykes, Scott Martin, Michael Davies, James W. T. Yates, Matthias Hoch, Helen E. Rollison and Barry JonesDrug Metabolism and Disposition September 2018, 46 (9) 1268-1276; DOI: https://doi.org/10.1124/dmd.118.081539
T
Takahashi, Shogo
- You have accessGlycyrrhizin Alleviates Nonalcoholic Steatohepatitis via Modulating Bile Acids and Meta-InflammationTingting Yan, Hong Wang, Lijuan Cao, Qiong Wang, Shogo Takahashi, Tomoki Yagai, Guolin Li, Kristopher W. Krausz, Guangji Wang, Frank J. Gonzalez and Haiping HaoDrug Metabolism and Disposition September 2018, 46 (9) 1310-1319; DOI: https://doi.org/10.1124/dmd.118.082008
Tóth, Beáta
- You have accessTransport Kinetics, Selective Inhibition, and Successful Prediction of In Vivo Inhibition of Rat Hepatic Organic Anion Transporting PolypeptidesKazuya Ishida, Mohammed Ullah, Beáta Tóth, Viktoria Juhasz and Jashvant D. UnadkatDrug Metabolism and Disposition September 2018, 46 (9) 1251-1258; DOI: https://doi.org/10.1124/dmd.118.080770
Tweedie, Donald
- Open AccessConsiderations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical RelevanceJane R. Kenny, Diane Ramsden, David B. Buckley, Shannon Dallas, Conrad Fung, Michael Mohutsky, Heidi J. Einolf, Liangfu Chen, Joshua G. Dekeyser, Maria Fitzgerald, Theunis C. Goosen, Y. Amy Siu, Robert L. Walsky, George Zhang, Donald Tweedie and Niresh HariparsadDrug Metabolism and Disposition September 2018, 46 (9) 1285-1303; DOI: https://doi.org/10.1124/dmd.118.081927
U
Ullah, Mohammed
- You have accessTransport Kinetics, Selective Inhibition, and Successful Prediction of In Vivo Inhibition of Rat Hepatic Organic Anion Transporting PolypeptidesKazuya Ishida, Mohammed Ullah, Beáta Tóth, Viktoria Juhasz and Jashvant D. UnadkatDrug Metabolism and Disposition September 2018, 46 (9) 1251-1258; DOI: https://doi.org/10.1124/dmd.118.080770
Unadkat, Jashvant D.
- You have accessTransport Kinetics, Selective Inhibition, and Successful Prediction of In Vivo Inhibition of Rat Hepatic Organic Anion Transporting PolypeptidesKazuya Ishida, Mohammed Ullah, Beáta Tóth, Viktoria Juhasz and Jashvant D. UnadkatDrug Metabolism and Disposition September 2018, 46 (9) 1251-1258; DOI: https://doi.org/10.1124/dmd.118.080770
W
Wagner, David J.
- You have accessDisposition of Methamphetamine and Major Metabolites in Mice: Role of Organic Cation Transporter 3 in Tissue-Selective Accumulation of Para-HydroxymethamphetamineDavid J. Wagner, Laura M. Shireman, Sojung Ahn, Danny D. Shen and Joanne WangDrug Metabolism and Disposition September 2018, 46 (9) 1277-1284; DOI: https://doi.org/10.1124/dmd.118.082131
Walsky, Robert L.
- Open AccessConsiderations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical RelevanceJane R. Kenny, Diane Ramsden, David B. Buckley, Shannon Dallas, Conrad Fung, Michael Mohutsky, Heidi J. Einolf, Liangfu Chen, Joshua G. Dekeyser, Maria Fitzgerald, Theunis C. Goosen, Y. Amy Siu, Robert L. Walsky, George Zhang, Donald Tweedie and Niresh HariparsadDrug Metabolism and Disposition September 2018, 46 (9) 1285-1303; DOI: https://doi.org/10.1124/dmd.118.081927
Wang, Guangji
- You have accessGlycyrrhizin Alleviates Nonalcoholic Steatohepatitis via Modulating Bile Acids and Meta-InflammationTingting Yan, Hong Wang, Lijuan Cao, Qiong Wang, Shogo Takahashi, Tomoki Yagai, Guolin Li, Kristopher W. Krausz, Guangji Wang, Frank J. Gonzalez and Haiping HaoDrug Metabolism and Disposition September 2018, 46 (9) 1310-1319; DOI: https://doi.org/10.1124/dmd.118.082008
Wang, Hong
- You have accessGlycyrrhizin Alleviates Nonalcoholic Steatohepatitis via Modulating Bile Acids and Meta-InflammationTingting Yan, Hong Wang, Lijuan Cao, Qiong Wang, Shogo Takahashi, Tomoki Yagai, Guolin Li, Kristopher W. Krausz, Guangji Wang, Frank J. Gonzalez and Haiping HaoDrug Metabolism and Disposition September 2018, 46 (9) 1310-1319; DOI: https://doi.org/10.1124/dmd.118.082008
Wang, Hongbing
- You have accessThe Roles of Xenobiotic Receptors: Beyond Chemical DispositionBryan Mackowiak, Jessica Hodge, Sydney Stern and Hongbing WangDrug Metabolism and Disposition September 2018, 46 (9) 1361-1371; DOI: https://doi.org/10.1124/dmd.118.081042
Wang, Joanne
- You have accessDisposition of Methamphetamine and Major Metabolites in Mice: Role of Organic Cation Transporter 3 in Tissue-Selective Accumulation of Para-HydroxymethamphetamineDavid J. Wagner, Laura M. Shireman, Sojung Ahn, Danny D. Shen and Joanne WangDrug Metabolism and Disposition September 2018, 46 (9) 1277-1284; DOI: https://doi.org/10.1124/dmd.118.082131
Wang, Liewei
- You have accessSingle Nucleotide Polymorphisms (SNPs) Distant from Xenobiotic Response Elements Can Modulate Aryl Hydrocarbon Receptor Function: SNP-Dependent CYP1A1 InductionDuan Liu, Sisi Qin, Balmiki Ray, Krishna R. Kalari, Liewei Wang and Richard M. WeinshilboumDrug Metabolism and Disposition September 2018, 46 (9) 1372-1381; DOI: https://doi.org/10.1124/dmd.118.082164
Wang, Qiong
- You have accessGlycyrrhizin Alleviates Nonalcoholic Steatohepatitis via Modulating Bile Acids and Meta-InflammationTingting Yan, Hong Wang, Lijuan Cao, Qiong Wang, Shogo Takahashi, Tomoki Yagai, Guolin Li, Kristopher W. Krausz, Guangji Wang, Frank J. Gonzalez and Haiping HaoDrug Metabolism and Disposition September 2018, 46 (9) 1310-1319; DOI: https://doi.org/10.1124/dmd.118.082008
Weinshilboum, Richard M.
- You have accessSingle Nucleotide Polymorphisms (SNPs) Distant from Xenobiotic Response Elements Can Modulate Aryl Hydrocarbon Receptor Function: SNP-Dependent CYP1A1 InductionDuan Liu, Sisi Qin, Balmiki Ray, Krishna R. Kalari, Liewei Wang and Richard M. WeinshilboumDrug Metabolism and Disposition September 2018, 46 (9) 1372-1381; DOI: https://doi.org/10.1124/dmd.118.082164
Wen, Qiang
- You have accessContent and Activities of UGT2B7 in Human Liver In Vitro and Predicted In Vivo: A Bottom-Up ApproachChen Xu, Jie Gao, Hai-Feng Zhang, Na Gao, Yuan-yuan Guo, Yan Fang, Qiang Wen and Hai-Ling QiaoDrug Metabolism and Disposition September 2018, 46 (9) 1351-1359; DOI: https://doi.org/10.1124/dmd.118.082024
West, Raymond E.
- You have accessDecreased Kidney Function Is Associated with Enhanced Hepatic Flavin Monooxygenase Activity and Increased Circulating Trimethylamine N-Oxide Concentrations in MiceCassandra Johnson, Alexander J. Prokopienko, Raymond E. West, Thomas D. Nolin and Jason R. StubbsDrug Metabolism and Disposition September 2018, 46 (9) 1304-1309; DOI: https://doi.org/10.1124/dmd.118.081646
Westphal, Koen G. C.
- You have accessRecellularized Native Kidney Scaffolds as a Novel Tool in Nephrotoxicity ScreeningMichele Fedecostante, Koen G. C. Westphal, Michele F. Buono, Natalia Sanchez Romero, Martijn J. Wilmer, Janis Kerkering, Pedro Miguel Baptista, Joost G. Hoenderop and Rosalinde MasereeuwDrug Metabolism and Disposition September 2018, 46 (9) 1338-1350; DOI: https://doi.org/10.1124/dmd.118.080721
Wilmer, Martijn J.
- You have accessRecellularized Native Kidney Scaffolds as a Novel Tool in Nephrotoxicity ScreeningMichele Fedecostante, Koen G. C. Westphal, Michele F. Buono, Natalia Sanchez Romero, Martijn J. Wilmer, Janis Kerkering, Pedro Miguel Baptista, Joost G. Hoenderop and Rosalinde MasereeuwDrug Metabolism and Disposition September 2018, 46 (9) 1338-1350; DOI: https://doi.org/10.1124/dmd.118.080721
Wilson, Joanne
- You have accessAn Investigation into the Prediction of the Plasma Concentration-Time Profile and Its Interindividual Variability for a Range of Flavin-Containing Monooxygenase Substrates Using a Physiologically Based Pharmacokinetic Modeling ApproachVenkatesh Pilla Reddy, Barry C. Jones, Nicola Colclough, Abhishek Srivastava, Joanne Wilson and Danxi LiDrug Metabolism and Disposition September 2018, 46 (9) 1259-1267; DOI: https://doi.org/10.1124/dmd.118.080648
X
Xu, Chen
- You have accessContent and Activities of UGT2B7 in Human Liver In Vitro and Predicted In Vivo: A Bottom-Up ApproachChen Xu, Jie Gao, Hai-Feng Zhang, Na Gao, Yuan-yuan Guo, Yan Fang, Qiang Wen and Hai-Ling QiaoDrug Metabolism and Disposition September 2018, 46 (9) 1351-1359; DOI: https://doi.org/10.1124/dmd.118.082024
Y
Yagai, Tomoki
- You have accessGlycyrrhizin Alleviates Nonalcoholic Steatohepatitis via Modulating Bile Acids and Meta-InflammationTingting Yan, Hong Wang, Lijuan Cao, Qiong Wang, Shogo Takahashi, Tomoki Yagai, Guolin Li, Kristopher W. Krausz, Guangji Wang, Frank J. Gonzalez and Haiping HaoDrug Metabolism and Disposition September 2018, 46 (9) 1310-1319; DOI: https://doi.org/10.1124/dmd.118.082008
Yan, Tingting
- You have accessGlycyrrhizin Alleviates Nonalcoholic Steatohepatitis via Modulating Bile Acids and Meta-InflammationTingting Yan, Hong Wang, Lijuan Cao, Qiong Wang, Shogo Takahashi, Tomoki Yagai, Guolin Li, Kristopher W. Krausz, Guangji Wang, Frank J. Gonzalez and Haiping HaoDrug Metabolism and Disposition September 2018, 46 (9) 1310-1319; DOI: https://doi.org/10.1124/dmd.118.082008
Yates, James W. T.
- You have accessComplete Substrate Inhibition of Cytochrome P450 2C8 by AZD9496, an Oral Selective Estrogen Receptor DegraderTashinga E. Bapiro, Andy Sykes, Scott Martin, Michael Davies, James W. T. Yates, Matthias Hoch, Helen E. Rollison and Barry JonesDrug Metabolism and Disposition September 2018, 46 (9) 1268-1276; DOI: https://doi.org/10.1124/dmd.118.081539
Yu, Songda
- You have accessDifferences in the In Vivo and In Vitro Metabolism of Imrecoxib in Humans: Formation of the Rate-Limiting Aldehyde IntermediateXiangyu Hou, Jialan Zhou, Songda Yu, Lei Zhou, Yifan Zhang, Dafang Zhong and Xiaoyan ChenDrug Metabolism and Disposition September 2018, 46 (9) 1320-1328; DOI: https://doi.org/10.1124/dmd.118.081182
Z
Zhang, George
- Open AccessConsiderations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical RelevanceJane R. Kenny, Diane Ramsden, David B. Buckley, Shannon Dallas, Conrad Fung, Michael Mohutsky, Heidi J. Einolf, Liangfu Chen, Joshua G. Dekeyser, Maria Fitzgerald, Theunis C. Goosen, Y. Amy Siu, Robert L. Walsky, George Zhang, Donald Tweedie and Niresh HariparsadDrug Metabolism and Disposition September 2018, 46 (9) 1285-1303; DOI: https://doi.org/10.1124/dmd.118.081927
Zhang, Hai-Feng
- You have accessContent and Activities of UGT2B7 in Human Liver In Vitro and Predicted In Vivo: A Bottom-Up ApproachChen Xu, Jie Gao, Hai-Feng Zhang, Na Gao, Yuan-yuan Guo, Yan Fang, Qiang Wen and Hai-Ling QiaoDrug Metabolism and Disposition September 2018, 46 (9) 1351-1359; DOI: https://doi.org/10.1124/dmd.118.082024
Zhang, Yifan
- You have accessDifferences in the In Vivo and In Vitro Metabolism of Imrecoxib in Humans: Formation of the Rate-Limiting Aldehyde IntermediateXiangyu Hou, Jialan Zhou, Songda Yu, Lei Zhou, Yifan Zhang, Dafang Zhong and Xiaoyan ChenDrug Metabolism and Disposition September 2018, 46 (9) 1320-1328; DOI: https://doi.org/10.1124/dmd.118.081182
Zhong, Dafang
- You have accessDifferences in the In Vivo and In Vitro Metabolism of Imrecoxib in Humans: Formation of the Rate-Limiting Aldehyde IntermediateXiangyu Hou, Jialan Zhou, Songda Yu, Lei Zhou, Yifan Zhang, Dafang Zhong and Xiaoyan ChenDrug Metabolism and Disposition September 2018, 46 (9) 1320-1328; DOI: https://doi.org/10.1124/dmd.118.081182
Zhou, Jialan
- You have accessDifferences in the In Vivo and In Vitro Metabolism of Imrecoxib in Humans: Formation of the Rate-Limiting Aldehyde IntermediateXiangyu Hou, Jialan Zhou, Songda Yu, Lei Zhou, Yifan Zhang, Dafang Zhong and Xiaoyan ChenDrug Metabolism and Disposition September 2018, 46 (9) 1320-1328; DOI: https://doi.org/10.1124/dmd.118.081182
Zhou, Lei
- You have accessDifferences in the In Vivo and In Vitro Metabolism of Imrecoxib in Humans: Formation of the Rate-Limiting Aldehyde IntermediateXiangyu Hou, Jialan Zhou, Songda Yu, Lei Zhou, Yifan Zhang, Dafang Zhong and Xiaoyan ChenDrug Metabolism and Disposition September 2018, 46 (9) 1320-1328; DOI: https://doi.org/10.1124/dmd.118.081182
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