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Review ArticleArticle

Efavirenz Metabolism: Influence of Polymorphic CYP2B6 Variants and Stereochemistry

Pan-Fen Wang, Alicia Neiner and Evan D. Kharasch
Drug Metabolism and Disposition October 2019, 47 (10) 1195-1205; DOI: https://doi.org/10.1124/dmd.119.086348
Pan-Fen Wang
Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina (P.-F.W., E.D.K.) and Department of Anesthesiology, Washington University in St. Louis, St. Louis, Missouri (A.N.)
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Alicia Neiner
Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina (P.-F.W., E.D.K.) and Department of Anesthesiology, Washington University in St. Louis, St. Louis, Missouri (A.N.)
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Evan D. Kharasch
Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina (P.-F.W., E.D.K.) and Department of Anesthesiology, Washington University in St. Louis, St. Louis, Missouri (A.N.)
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Article Information

vol. 47 no. 10 1195-1205
DOI 
https://doi.org/10.1124/dmd.119.086348
PubMed 
31324697

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received January 11, 2019
  • Accepted July 10, 2019
  • Published online September 20, 2019.

Article Versions

  • Earlier version (July 19, 2019 - 06:00).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2019 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Pan-Fen Wang,
  2. Alicia Neiner, and
  3. Evan D. Kharasch
  1. Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina (P.-F.W., E.D.K.) and Department of Anesthesiology, Washington University in St. Louis, St. Louis, Missouri (A.N.)
  1. Address correspondence to:
    Dr. Evan D. Kharasch, Department of Anesthesiology, Duke University School of Medicine, Box 3094, 905 S. LaSalle St, GSRB1 Room 2031, Durham, NC 27710. E-mail: evan.kharasch{at}duke.edu
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Drug Metabolism and Disposition: 47 (10)
Drug Metabolism and Disposition
Vol. 47, Issue 10
1 Oct 2019
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Review ArticleArticle

CYP2B6 Efavirenz Metabolism Genetics and Stereoselectivity

Pan-Fen Wang, Alicia Neiner and Evan D. Kharasch
Drug Metabolism and Disposition October 1, 2019, 47 (10) 1195-1205; DOI: https://doi.org/10.1124/dmd.119.086348

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Review ArticleArticle

CYP2B6 Efavirenz Metabolism Genetics and Stereoselectivity

Pan-Fen Wang, Alicia Neiner and Evan D. Kharasch
Drug Metabolism and Disposition October 1, 2019, 47 (10) 1195-1205; DOI: https://doi.org/10.1124/dmd.119.086348
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