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Drug Metabolism & Disposition

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    • Current Issue
    • Fast Forward
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Index by author

November 01, 2019; Volume 47,Issue 11
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Abouda, Arsany A.

    1. You have access
      Interindividual Variation in CYP3A Activity Influences Lapatinib Bioactivation
      Jennifer E. Bissada, Vivian Truong, Arsany A. Abouda, Kahari J. Wines, Rachel D. Crouch and Klarissa D. Jackson
      Drug Metabolism and Disposition November 2019, 47 (11) 1257-1269; DOI: https://doi.org/10.1124/dmd.119.088823
  2. Ando, Osamu

    1. You have access
      Elucidation of N1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters
      Takeshi Miyake, Tadahaya Mizuno, Issey Takehara, Tatsuki Mochizuki, Miyuki Kimura, Shunji Matsuki, Shin Irie, Nobuaki Watanabe, Yukio Kato, Ichiro Ieiri, Kazuya Maeda, Osamu Ando and Hiroyuki Kusuhara
      Drug Metabolism and Disposition November 2019, 47 (11) 1270-1280; DOI: https://doi.org/10.1124/dmd.119.087262

B

  1. Bai, Haihong

    1. Development of a Gold Nanoparticle–Functionalized Surface Plasmon Resonance Assay for the Sensitive Detection of Monoclonal Antibodies and Its Application in Pharmacokinetics
      You have access
      Development of a Gold Nanoparticle–Functionalized Surface Plasmon Resonance Assay for the Sensitive Detection of Monoclonal Antibodies and Its Application in Pharmacokinetics
      Haihong Bai, Mei Yuan, Xiaojing Wang, Xinghe Wang and Jinjing Che
      Drug Metabolism and Disposition November 2019, 47 (11) 1361-1367; DOI: https://doi.org/10.1124/dmd.119.086249
  2. Bangur, Eva-Henriette

    1. Metabolism of Strained Rings: Glutathione <em>S</em>-transferase–Catalyzed Formation of a Glutathione-Conjugated Spiro-azetidine without Prior Bioactivation
      You have access
      Metabolism of Strained Rings: Glutathione S-transferase–Catalyzed Formation of a Glutathione-Conjugated Spiro-azetidine without Prior Bioactivation
      Xue-Qing Li, Gunnar Grönberg, Eva-Henriette Bangur, Martin A. Hayes, Neal Castagnoli and Lars Weidolf
      Drug Metabolism and Disposition November 2019, 47 (11) 1247-1256; DOI: https://doi.org/10.1124/dmd.119.088658
  3. Berg, Jeannette Zinggeler

    1. You have access
      A Role for the Orphan Human Cytochrome P450 2S1 in Polyunsaturated Fatty Acid ω-1 Hydroxylation Using an Untargeted Metabolomic Approach
      Mostafa I. Fekry, Yi Xiao, Jeannette Zinggeler Berg and F. Peter Guengerich
      Drug Metabolism and Disposition November 2019, 47 (11) 1325-1332; DOI: https://doi.org/10.1124/dmd.119.089086
  4. Bissada, Jennifer E.

    1. You have access
      Interindividual Variation in CYP3A Activity Influences Lapatinib Bioactivation
      Jennifer E. Bissada, Vivian Truong, Arsany A. Abouda, Kahari J. Wines, Rachel D. Crouch and Klarissa D. Jackson
      Drug Metabolism and Disposition November 2019, 47 (11) 1257-1269; DOI: https://doi.org/10.1124/dmd.119.088823

C

  1. Castagnoli, Neal

    1. Metabolism of Strained Rings: Glutathione <em>S</em>-transferase–Catalyzed Formation of a Glutathione-Conjugated Spiro-azetidine without Prior Bioactivation
      You have access
      Metabolism of Strained Rings: Glutathione S-transferase–Catalyzed Formation of a Glutathione-Conjugated Spiro-azetidine without Prior Bioactivation
      Xue-Qing Li, Gunnar Grönberg, Eva-Henriette Bangur, Martin A. Hayes, Neal Castagnoli and Lars Weidolf
      Drug Metabolism and Disposition November 2019, 47 (11) 1247-1256; DOI: https://doi.org/10.1124/dmd.119.088658
  2. Chan, Eric Chun Yong

    1. Systematic Development and Verification of a Physiologically Based Pharmacokinetic Model of Rivaroxaban
      You have access
      Systematic Development and Verification of a Physiologically Based Pharmacokinetic Model of Rivaroxaban
      Eleanor Jing Yi Cheong, Denise Wun Xi Teo, Denise Xin Yi Chua and Eric Chun Yong Chan
      Drug Metabolism and Disposition November 2019, 47 (11) 1291-1306; DOI: https://doi.org/10.1124/dmd.119.086918
  3. Chang, Jae H.

    1. You have access
      Investigating the Impact of Albumin on the Liver Uptake of Pitavastatin and Warfarin in Nagase Analbuminemic Rats
      Jae H. Chang, Yi-Chen Chen, Jonathan Cheong, Robert S. Jones and Jodie Pang
      Drug Metabolism and Disposition November 2019, 47 (11) 1307-1313; DOI: https://doi.org/10.1124/dmd.119.088278
  4. Che, Jinjing

    1. Development of a Gold Nanoparticle–Functionalized Surface Plasmon Resonance Assay for the Sensitive Detection of Monoclonal Antibodies and Its Application in Pharmacokinetics
      You have access
      Development of a Gold Nanoparticle–Functionalized Surface Plasmon Resonance Assay for the Sensitive Detection of Monoclonal Antibodies and Its Application in Pharmacokinetics
      Haihong Bai, Mei Yuan, Xiaojing Wang, Xinghe Wang and Jinjing Che
      Drug Metabolism and Disposition November 2019, 47 (11) 1361-1367; DOI: https://doi.org/10.1124/dmd.119.086249
  5. Chen, Min

    1. You have access
      The Molecular Mechanism Regulating Diurnal Rhythm of Flavin-Containing Monooxygenase 5 in Mouse Liver
      Min Chen, Baozhang Guan, Haiman Xu, Fangjun Yu, Tianpeng Zhang and Baojian Wu
      Drug Metabolism and Disposition November 2019, 47 (11) 1333-1342; DOI: https://doi.org/10.1124/dmd.119.088450
  6. Chen, Weiqi

    1. You have access
      Enhanced and Persistent Inhibition of Organic Cation Transporter 1 Activity by Preincubation of Cyclosporine A
      Erika Panfen, Weiqi Chen, Yueping Zhang, Michael Sinz, Punit Marathe, Jinping Gan and Hong Shen
      Drug Metabolism and Disposition November 2019, 47 (11) 1352-1360; DOI: https://doi.org/10.1124/dmd.119.087197
  7. Chen, Yi-Chen

    1. You have access
      Investigating the Impact of Albumin on the Liver Uptake of Pitavastatin and Warfarin in Nagase Analbuminemic Rats
      Jae H. Chang, Yi-Chen Chen, Jonathan Cheong, Robert S. Jones and Jodie Pang
      Drug Metabolism and Disposition November 2019, 47 (11) 1307-1313; DOI: https://doi.org/10.1124/dmd.119.088278
  8. Cheong, Eleanor Jing Yi

    1. Systematic Development and Verification of a Physiologically Based Pharmacokinetic Model of Rivaroxaban
      You have access
      Systematic Development and Verification of a Physiologically Based Pharmacokinetic Model of Rivaroxaban
      Eleanor Jing Yi Cheong, Denise Wun Xi Teo, Denise Xin Yi Chua and Eric Chun Yong Chan
      Drug Metabolism and Disposition November 2019, 47 (11) 1291-1306; DOI: https://doi.org/10.1124/dmd.119.086918
  9. Cheong, Jonathan

    1. You have access
      Investigating the Impact of Albumin on the Liver Uptake of Pitavastatin and Warfarin in Nagase Analbuminemic Rats
      Jae H. Chang, Yi-Chen Chen, Jonathan Cheong, Robert S. Jones and Jodie Pang
      Drug Metabolism and Disposition November 2019, 47 (11) 1307-1313; DOI: https://doi.org/10.1124/dmd.119.088278
  10. Chua, Denise Xin Yi

    1. Systematic Development and Verification of a Physiologically Based Pharmacokinetic Model of Rivaroxaban
      You have access
      Systematic Development and Verification of a Physiologically Based Pharmacokinetic Model of Rivaroxaban
      Eleanor Jing Yi Cheong, Denise Wun Xi Teo, Denise Xin Yi Chua and Eric Chun Yong Chan
      Drug Metabolism and Disposition November 2019, 47 (11) 1291-1306; DOI: https://doi.org/10.1124/dmd.119.086918
  11. Court, Michael H.

    1. You have access
      Absolute Quantitation of Drug-Metabolizing Cytochrome P450 Enzymes and Accessory Proteins in Dog Liver Microsomes Using Label-Free Standard-Free Analysis Reveals Interbreed Variability
      Stephanie E. Martinez, Jian Shi, Hao-Jie Zhu, Tania E. Perez Jimenez, Zhaohui Zhu and Michael H. Court
      Drug Metabolism and Disposition November 2019, 47 (11) 1314-1324; DOI: https://doi.org/10.1124/dmd.119.088070
  12. Crouch, Rachel D.

    1. You have access
      Interindividual Variation in CYP3A Activity Influences Lapatinib Bioactivation
      Jennifer E. Bissada, Vivian Truong, Arsany A. Abouda, Kahari J. Wines, Rachel D. Crouch and Klarissa D. Jackson
      Drug Metabolism and Disposition November 2019, 47 (11) 1257-1269; DOI: https://doi.org/10.1124/dmd.119.088823

E

  1. Enokizono, Junichi

    1. Impact of Different Selectivity between Soluble and Membrane-bound Forms of Carcinoembryonic Antigen (CEA) on the Target-mediated Disposition of Anti-CEA Monoclonal Antibodies
      You have access
      Impact of Different Selectivity between Soluble and Membrane-bound Forms of Carcinoembryonic Antigen (CEA) on the Target-mediated Disposition of Anti-CEA Monoclonal Antibodies
      Junko Iwano, Daisuke Shinmi, Kazuhiro Masuda, Takashi Murakami and Junichi Enokizono
      Drug Metabolism and Disposition November 2019, 47 (11) 1240-1246; DOI: https://doi.org/10.1124/dmd.119.088179

F

  1. Fekry, Mostafa I.

    1. You have access
      A Role for the Orphan Human Cytochrome P450 2S1 in Polyunsaturated Fatty Acid ω-1 Hydroxylation Using an Untargeted Metabolomic Approach
      Mostafa I. Fekry, Yi Xiao, Jeannette Zinggeler Berg and F. Peter Guengerich
      Drug Metabolism and Disposition November 2019, 47 (11) 1325-1332; DOI: https://doi.org/10.1124/dmd.119.089086
  2. Feng, Yukun

    1. You have access
      Glutathione Conjugation and Protein Adduction Derived from Oxidative Debromination of Benzbromarone in Mice
      Hui Wang, Wenbao Wang, Bowen Gong, Zedan Wang, Yukun Feng, Weige Zhang, Shaojie Wang, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition November 2019, 47 (11) 1281-1290; DOI: https://doi.org/10.1124/dmd.119.087460

G

  1. Gan, Jinping

    1. You have access
      Enhanced and Persistent Inhibition of Organic Cation Transporter 1 Activity by Preincubation of Cyclosporine A
      Erika Panfen, Weiqi Chen, Yueping Zhang, Michael Sinz, Punit Marathe, Jinping Gan and Hong Shen
      Drug Metabolism and Disposition November 2019, 47 (11) 1352-1360; DOI: https://doi.org/10.1124/dmd.119.087197
  2. Gong, Bowen

    1. You have access
      Glutathione Conjugation and Protein Adduction Derived from Oxidative Debromination of Benzbromarone in Mice
      Hui Wang, Wenbao Wang, Bowen Gong, Zedan Wang, Yukun Feng, Weige Zhang, Shaojie Wang, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition November 2019, 47 (11) 1281-1290; DOI: https://doi.org/10.1124/dmd.119.087460
  3. Grönberg, Gunnar

    1. Metabolism of Strained Rings: Glutathione <em>S</em>-transferase–Catalyzed Formation of a Glutathione-Conjugated Spiro-azetidine without Prior Bioactivation
      You have access
      Metabolism of Strained Rings: Glutathione S-transferase–Catalyzed Formation of a Glutathione-Conjugated Spiro-azetidine without Prior Bioactivation
      Xue-Qing Li, Gunnar Grönberg, Eva-Henriette Bangur, Martin A. Hayes, Neal Castagnoli and Lars Weidolf
      Drug Metabolism and Disposition November 2019, 47 (11) 1247-1256; DOI: https://doi.org/10.1124/dmd.119.088658
  4. Guan, Baozhang

    1. You have access
      The Molecular Mechanism Regulating Diurnal Rhythm of Flavin-Containing Monooxygenase 5 in Mouse Liver
      Min Chen, Baozhang Guan, Haiman Xu, Fangjun Yu, Tianpeng Zhang and Baojian Wu
      Drug Metabolism and Disposition November 2019, 47 (11) 1333-1342; DOI: https://doi.org/10.1124/dmd.119.088450
  5. Guengerich, F. Peter

    1. You have access
      Kinetic Modeling of Steady-State Situations in Cytochrome P450 Enzyme Reactions
      F. Peter Guengerich
      Drug Metabolism and Disposition November 2019, 47 (11) 1232-1239; DOI: https://doi.org/10.1124/dmd.119.088732
    2. You have access
      A Role for the Orphan Human Cytochrome P450 2S1 in Polyunsaturated Fatty Acid ω-1 Hydroxylation Using an Untargeted Metabolomic Approach
      Mostafa I. Fekry, Yi Xiao, Jeannette Zinggeler Berg and F. Peter Guengerich
      Drug Metabolism and Disposition November 2019, 47 (11) 1325-1332; DOI: https://doi.org/10.1124/dmd.119.089086

H

  1. Han, Lifeng

    1. You have access
      Glucocorticoids Increase Renal Excretion of Urate in Mice by Downregulating Urate Transporter 1
      Gentao Li, Lifeng Han, Ruicong Ma, Khawar Saeed, Hui Xiong, Curtis D. Klaassen, Yuanfu Lu and Youcai Zhang
      Drug Metabolism and Disposition November 2019, 47 (11) 1343-1351; DOI: https://doi.org/10.1124/dmd.119.087700
  2. Hayes, Martin A.

    1. Metabolism of Strained Rings: Glutathione <em>S</em>-transferase–Catalyzed Formation of a Glutathione-Conjugated Spiro-azetidine without Prior Bioactivation
      You have access
      Metabolism of Strained Rings: Glutathione S-transferase–Catalyzed Formation of a Glutathione-Conjugated Spiro-azetidine without Prior Bioactivation
      Xue-Qing Li, Gunnar Grönberg, Eva-Henriette Bangur, Martin A. Hayes, Neal Castagnoli and Lars Weidolf
      Drug Metabolism and Disposition November 2019, 47 (11) 1247-1256; DOI: https://doi.org/10.1124/dmd.119.088658

I

  1. Ieiri, Ichiro

    1. You have access
      Elucidation of N1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters
      Takeshi Miyake, Tadahaya Mizuno, Issey Takehara, Tatsuki Mochizuki, Miyuki Kimura, Shunji Matsuki, Shin Irie, Nobuaki Watanabe, Yukio Kato, Ichiro Ieiri, Kazuya Maeda, Osamu Ando and Hiroyuki Kusuhara
      Drug Metabolism and Disposition November 2019, 47 (11) 1270-1280; DOI: https://doi.org/10.1124/dmd.119.087262
  2. Irie, Shin

    1. You have access
      Elucidation of N1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters
      Takeshi Miyake, Tadahaya Mizuno, Issey Takehara, Tatsuki Mochizuki, Miyuki Kimura, Shunji Matsuki, Shin Irie, Nobuaki Watanabe, Yukio Kato, Ichiro Ieiri, Kazuya Maeda, Osamu Ando and Hiroyuki Kusuhara
      Drug Metabolism and Disposition November 2019, 47 (11) 1270-1280; DOI: https://doi.org/10.1124/dmd.119.087262
  3. Iwano, Junko

    1. Impact of Different Selectivity between Soluble and Membrane-bound Forms of Carcinoembryonic Antigen (CEA) on the Target-mediated Disposition of Anti-CEA Monoclonal Antibodies
      You have access
      Impact of Different Selectivity between Soluble and Membrane-bound Forms of Carcinoembryonic Antigen (CEA) on the Target-mediated Disposition of Anti-CEA Monoclonal Antibodies
      Junko Iwano, Daisuke Shinmi, Kazuhiro Masuda, Takashi Murakami and Junichi Enokizono
      Drug Metabolism and Disposition November 2019, 47 (11) 1240-1246; DOI: https://doi.org/10.1124/dmd.119.088179

J

  1. Jackson, Klarissa D.

    1. You have access
      Interindividual Variation in CYP3A Activity Influences Lapatinib Bioactivation
      Jennifer E. Bissada, Vivian Truong, Arsany A. Abouda, Kahari J. Wines, Rachel D. Crouch and Klarissa D. Jackson
      Drug Metabolism and Disposition November 2019, 47 (11) 1257-1269; DOI: https://doi.org/10.1124/dmd.119.088823
  2. Jones, Robert S.

    1. You have access
      Investigating the Impact of Albumin on the Liver Uptake of Pitavastatin and Warfarin in Nagase Analbuminemic Rats
      Jae H. Chang, Yi-Chen Chen, Jonathan Cheong, Robert S. Jones and Jodie Pang
      Drug Metabolism and Disposition November 2019, 47 (11) 1307-1313; DOI: https://doi.org/10.1124/dmd.119.088278

K

  1. Kato, Yukio

    1. You have access
      Elucidation of N1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters
      Takeshi Miyake, Tadahaya Mizuno, Issey Takehara, Tatsuki Mochizuki, Miyuki Kimura, Shunji Matsuki, Shin Irie, Nobuaki Watanabe, Yukio Kato, Ichiro Ieiri, Kazuya Maeda, Osamu Ando and Hiroyuki Kusuhara
      Drug Metabolism and Disposition November 2019, 47 (11) 1270-1280; DOI: https://doi.org/10.1124/dmd.119.087262
  2. Kimura, Miyuki

    1. You have access
      Elucidation of N1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters
      Takeshi Miyake, Tadahaya Mizuno, Issey Takehara, Tatsuki Mochizuki, Miyuki Kimura, Shunji Matsuki, Shin Irie, Nobuaki Watanabe, Yukio Kato, Ichiro Ieiri, Kazuya Maeda, Osamu Ando and Hiroyuki Kusuhara
      Drug Metabolism and Disposition November 2019, 47 (11) 1270-1280; DOI: https://doi.org/10.1124/dmd.119.087262
  3. Klaassen, Curtis D.

    1. You have access
      Glucocorticoids Increase Renal Excretion of Urate in Mice by Downregulating Urate Transporter 1
      Gentao Li, Lifeng Han, Ruicong Ma, Khawar Saeed, Hui Xiong, Curtis D. Klaassen, Yuanfu Lu and Youcai Zhang
      Drug Metabolism and Disposition November 2019, 47 (11) 1343-1351; DOI: https://doi.org/10.1124/dmd.119.087700
  4. Kusuhara, Hiroyuki

    1. You have access
      Elucidation of N1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters
      Takeshi Miyake, Tadahaya Mizuno, Issey Takehara, Tatsuki Mochizuki, Miyuki Kimura, Shunji Matsuki, Shin Irie, Nobuaki Watanabe, Yukio Kato, Ichiro Ieiri, Kazuya Maeda, Osamu Ando and Hiroyuki Kusuhara
      Drug Metabolism and Disposition November 2019, 47 (11) 1270-1280; DOI: https://doi.org/10.1124/dmd.119.087262

L

  1. Li, Gentao

    1. You have access
      Glucocorticoids Increase Renal Excretion of Urate in Mice by Downregulating Urate Transporter 1
      Gentao Li, Lifeng Han, Ruicong Ma, Khawar Saeed, Hui Xiong, Curtis D. Klaassen, Yuanfu Lu and Youcai Zhang
      Drug Metabolism and Disposition November 2019, 47 (11) 1343-1351; DOI: https://doi.org/10.1124/dmd.119.087700
  2. Li, Xue-Qing

    1. Metabolism of Strained Rings: Glutathione <em>S</em>-transferase–Catalyzed Formation of a Glutathione-Conjugated Spiro-azetidine without Prior Bioactivation
      You have access
      Metabolism of Strained Rings: Glutathione S-transferase–Catalyzed Formation of a Glutathione-Conjugated Spiro-azetidine without Prior Bioactivation
      Xue-Qing Li, Gunnar Grönberg, Eva-Henriette Bangur, Martin A. Hayes, Neal Castagnoli and Lars Weidolf
      Drug Metabolism and Disposition November 2019, 47 (11) 1247-1256; DOI: https://doi.org/10.1124/dmd.119.088658
  3. Lu, Yuanfu

    1. You have access
      Glucocorticoids Increase Renal Excretion of Urate in Mice by Downregulating Urate Transporter 1
      Gentao Li, Lifeng Han, Ruicong Ma, Khawar Saeed, Hui Xiong, Curtis D. Klaassen, Yuanfu Lu and Youcai Zhang
      Drug Metabolism and Disposition November 2019, 47 (11) 1343-1351; DOI: https://doi.org/10.1124/dmd.119.087700

M

  1. Ma, Ruicong

    1. You have access
      Glucocorticoids Increase Renal Excretion of Urate in Mice by Downregulating Urate Transporter 1
      Gentao Li, Lifeng Han, Ruicong Ma, Khawar Saeed, Hui Xiong, Curtis D. Klaassen, Yuanfu Lu and Youcai Zhang
      Drug Metabolism and Disposition November 2019, 47 (11) 1343-1351; DOI: https://doi.org/10.1124/dmd.119.087700
  2. Maeda, Kazuya

    1. You have access
      Elucidation of N1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters
      Takeshi Miyake, Tadahaya Mizuno, Issey Takehara, Tatsuki Mochizuki, Miyuki Kimura, Shunji Matsuki, Shin Irie, Nobuaki Watanabe, Yukio Kato, Ichiro Ieiri, Kazuya Maeda, Osamu Ando and Hiroyuki Kusuhara
      Drug Metabolism and Disposition November 2019, 47 (11) 1270-1280; DOI: https://doi.org/10.1124/dmd.119.087262
  3. Marathe, Punit

    1. You have access
      Enhanced and Persistent Inhibition of Organic Cation Transporter 1 Activity by Preincubation of Cyclosporine A
      Erika Panfen, Weiqi Chen, Yueping Zhang, Michael Sinz, Punit Marathe, Jinping Gan and Hong Shen
      Drug Metabolism and Disposition November 2019, 47 (11) 1352-1360; DOI: https://doi.org/10.1124/dmd.119.087197
  4. Martinez, Stephanie E.

    1. You have access
      Absolute Quantitation of Drug-Metabolizing Cytochrome P450 Enzymes and Accessory Proteins in Dog Liver Microsomes Using Label-Free Standard-Free Analysis Reveals Interbreed Variability
      Stephanie E. Martinez, Jian Shi, Hao-Jie Zhu, Tania E. Perez Jimenez, Zhaohui Zhu and Michael H. Court
      Drug Metabolism and Disposition November 2019, 47 (11) 1314-1324; DOI: https://doi.org/10.1124/dmd.119.088070
  5. Masuda, Kazuhiro

    1. Impact of Different Selectivity between Soluble and Membrane-bound Forms of Carcinoembryonic Antigen (CEA) on the Target-mediated Disposition of Anti-CEA Monoclonal Antibodies
      You have access
      Impact of Different Selectivity between Soluble and Membrane-bound Forms of Carcinoembryonic Antigen (CEA) on the Target-mediated Disposition of Anti-CEA Monoclonal Antibodies
      Junko Iwano, Daisuke Shinmi, Kazuhiro Masuda, Takashi Murakami and Junichi Enokizono
      Drug Metabolism and Disposition November 2019, 47 (11) 1240-1246; DOI: https://doi.org/10.1124/dmd.119.088179
  6. Matsuki, Shunji

    1. You have access
      Elucidation of N1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters
      Takeshi Miyake, Tadahaya Mizuno, Issey Takehara, Tatsuki Mochizuki, Miyuki Kimura, Shunji Matsuki, Shin Irie, Nobuaki Watanabe, Yukio Kato, Ichiro Ieiri, Kazuya Maeda, Osamu Ando and Hiroyuki Kusuhara
      Drug Metabolism and Disposition November 2019, 47 (11) 1270-1280; DOI: https://doi.org/10.1124/dmd.119.087262
  7. Miyake, Takeshi

    1. You have access
      Elucidation of N1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters
      Takeshi Miyake, Tadahaya Mizuno, Issey Takehara, Tatsuki Mochizuki, Miyuki Kimura, Shunji Matsuki, Shin Irie, Nobuaki Watanabe, Yukio Kato, Ichiro Ieiri, Kazuya Maeda, Osamu Ando and Hiroyuki Kusuhara
      Drug Metabolism and Disposition November 2019, 47 (11) 1270-1280; DOI: https://doi.org/10.1124/dmd.119.087262
  8. Mizuno, Tadahaya

    1. You have access
      Elucidation of N1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters
      Takeshi Miyake, Tadahaya Mizuno, Issey Takehara, Tatsuki Mochizuki, Miyuki Kimura, Shunji Matsuki, Shin Irie, Nobuaki Watanabe, Yukio Kato, Ichiro Ieiri, Kazuya Maeda, Osamu Ando and Hiroyuki Kusuhara
      Drug Metabolism and Disposition November 2019, 47 (11) 1270-1280; DOI: https://doi.org/10.1124/dmd.119.087262
  9. Mochizuki, Tatsuki

    1. You have access
      Elucidation of N1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters
      Takeshi Miyake, Tadahaya Mizuno, Issey Takehara, Tatsuki Mochizuki, Miyuki Kimura, Shunji Matsuki, Shin Irie, Nobuaki Watanabe, Yukio Kato, Ichiro Ieiri, Kazuya Maeda, Osamu Ando and Hiroyuki Kusuhara
      Drug Metabolism and Disposition November 2019, 47 (11) 1270-1280; DOI: https://doi.org/10.1124/dmd.119.087262
  10. Murakami, Takashi

    1. Impact of Different Selectivity between Soluble and Membrane-bound Forms of Carcinoembryonic Antigen (CEA) on the Target-mediated Disposition of Anti-CEA Monoclonal Antibodies
      You have access
      Impact of Different Selectivity between Soluble and Membrane-bound Forms of Carcinoembryonic Antigen (CEA) on the Target-mediated Disposition of Anti-CEA Monoclonal Antibodies
      Junko Iwano, Daisuke Shinmi, Kazuhiro Masuda, Takashi Murakami and Junichi Enokizono
      Drug Metabolism and Disposition November 2019, 47 (11) 1240-1246; DOI: https://doi.org/10.1124/dmd.119.088179

P

  1. Panfen, Erika

    1. You have access
      Enhanced and Persistent Inhibition of Organic Cation Transporter 1 Activity by Preincubation of Cyclosporine A
      Erika Panfen, Weiqi Chen, Yueping Zhang, Michael Sinz, Punit Marathe, Jinping Gan and Hong Shen
      Drug Metabolism and Disposition November 2019, 47 (11) 1352-1360; DOI: https://doi.org/10.1124/dmd.119.087197
  2. Pang, Jodie

    1. You have access
      Investigating the Impact of Albumin on the Liver Uptake of Pitavastatin and Warfarin in Nagase Analbuminemic Rats
      Jae H. Chang, Yi-Chen Chen, Jonathan Cheong, Robert S. Jones and Jodie Pang
      Drug Metabolism and Disposition November 2019, 47 (11) 1307-1313; DOI: https://doi.org/10.1124/dmd.119.088278
  3. Peng, Ying

    1. You have access
      Glutathione Conjugation and Protein Adduction Derived from Oxidative Debromination of Benzbromarone in Mice
      Hui Wang, Wenbao Wang, Bowen Gong, Zedan Wang, Yukun Feng, Weige Zhang, Shaojie Wang, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition November 2019, 47 (11) 1281-1290; DOI: https://doi.org/10.1124/dmd.119.087460
  4. Perez Jimenez, Tania E.

    1. You have access
      Absolute Quantitation of Drug-Metabolizing Cytochrome P450 Enzymes and Accessory Proteins in Dog Liver Microsomes Using Label-Free Standard-Free Analysis Reveals Interbreed Variability
      Stephanie E. Martinez, Jian Shi, Hao-Jie Zhu, Tania E. Perez Jimenez, Zhaohui Zhu and Michael H. Court
      Drug Metabolism and Disposition November 2019, 47 (11) 1314-1324; DOI: https://doi.org/10.1124/dmd.119.088070

S

  1. Saeed, Khawar

    1. You have access
      Glucocorticoids Increase Renal Excretion of Urate in Mice by Downregulating Urate Transporter 1
      Gentao Li, Lifeng Han, Ruicong Ma, Khawar Saeed, Hui Xiong, Curtis D. Klaassen, Yuanfu Lu and Youcai Zhang
      Drug Metabolism and Disposition November 2019, 47 (11) 1343-1351; DOI: https://doi.org/10.1124/dmd.119.087700
  2. Shen, Hong

    1. You have access
      Enhanced and Persistent Inhibition of Organic Cation Transporter 1 Activity by Preincubation of Cyclosporine A
      Erika Panfen, Weiqi Chen, Yueping Zhang, Michael Sinz, Punit Marathe, Jinping Gan and Hong Shen
      Drug Metabolism and Disposition November 2019, 47 (11) 1352-1360; DOI: https://doi.org/10.1124/dmd.119.087197
  3. Shi, Jian

    1. You have access
      Absolute Quantitation of Drug-Metabolizing Cytochrome P450 Enzymes and Accessory Proteins in Dog Liver Microsomes Using Label-Free Standard-Free Analysis Reveals Interbreed Variability
      Stephanie E. Martinez, Jian Shi, Hao-Jie Zhu, Tania E. Perez Jimenez, Zhaohui Zhu and Michael H. Court
      Drug Metabolism and Disposition November 2019, 47 (11) 1314-1324; DOI: https://doi.org/10.1124/dmd.119.088070
  4. Shinmi, Daisuke

    1. Impact of Different Selectivity between Soluble and Membrane-bound Forms of Carcinoembryonic Antigen (CEA) on the Target-mediated Disposition of Anti-CEA Monoclonal Antibodies
      You have access
      Impact of Different Selectivity between Soluble and Membrane-bound Forms of Carcinoembryonic Antigen (CEA) on the Target-mediated Disposition of Anti-CEA Monoclonal Antibodies
      Junko Iwano, Daisuke Shinmi, Kazuhiro Masuda, Takashi Murakami and Junichi Enokizono
      Drug Metabolism and Disposition November 2019, 47 (11) 1240-1246; DOI: https://doi.org/10.1124/dmd.119.088179
  5. Sinz, Michael

    1. You have access
      Enhanced and Persistent Inhibition of Organic Cation Transporter 1 Activity by Preincubation of Cyclosporine A
      Erika Panfen, Weiqi Chen, Yueping Zhang, Michael Sinz, Punit Marathe, Jinping Gan and Hong Shen
      Drug Metabolism and Disposition November 2019, 47 (11) 1352-1360; DOI: https://doi.org/10.1124/dmd.119.087197

T

  1. Takehara, Issey

    1. You have access
      Elucidation of N1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters
      Takeshi Miyake, Tadahaya Mizuno, Issey Takehara, Tatsuki Mochizuki, Miyuki Kimura, Shunji Matsuki, Shin Irie, Nobuaki Watanabe, Yukio Kato, Ichiro Ieiri, Kazuya Maeda, Osamu Ando and Hiroyuki Kusuhara
      Drug Metabolism and Disposition November 2019, 47 (11) 1270-1280; DOI: https://doi.org/10.1124/dmd.119.087262
  2. Teo, Denise Wun Xi

    1. Systematic Development and Verification of a Physiologically Based Pharmacokinetic Model of Rivaroxaban
      You have access
      Systematic Development and Verification of a Physiologically Based Pharmacokinetic Model of Rivaroxaban
      Eleanor Jing Yi Cheong, Denise Wun Xi Teo, Denise Xin Yi Chua and Eric Chun Yong Chan
      Drug Metabolism and Disposition November 2019, 47 (11) 1291-1306; DOI: https://doi.org/10.1124/dmd.119.086918
  3. Truong, Vivian

    1. You have access
      Interindividual Variation in CYP3A Activity Influences Lapatinib Bioactivation
      Jennifer E. Bissada, Vivian Truong, Arsany A. Abouda, Kahari J. Wines, Rachel D. Crouch and Klarissa D. Jackson
      Drug Metabolism and Disposition November 2019, 47 (11) 1257-1269; DOI: https://doi.org/10.1124/dmd.119.088823

W

  1. Wang, Hui

    1. You have access
      Glutathione Conjugation and Protein Adduction Derived from Oxidative Debromination of Benzbromarone in Mice
      Hui Wang, Wenbao Wang, Bowen Gong, Zedan Wang, Yukun Feng, Weige Zhang, Shaojie Wang, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition November 2019, 47 (11) 1281-1290; DOI: https://doi.org/10.1124/dmd.119.087460
  2. Wang, Shaojie

    1. You have access
      Glutathione Conjugation and Protein Adduction Derived from Oxidative Debromination of Benzbromarone in Mice
      Hui Wang, Wenbao Wang, Bowen Gong, Zedan Wang, Yukun Feng, Weige Zhang, Shaojie Wang, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition November 2019, 47 (11) 1281-1290; DOI: https://doi.org/10.1124/dmd.119.087460
  3. Wang, Wenbao

    1. You have access
      Glutathione Conjugation and Protein Adduction Derived from Oxidative Debromination of Benzbromarone in Mice
      Hui Wang, Wenbao Wang, Bowen Gong, Zedan Wang, Yukun Feng, Weige Zhang, Shaojie Wang, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition November 2019, 47 (11) 1281-1290; DOI: https://doi.org/10.1124/dmd.119.087460
  4. Wang, Xiaojing

    1. Development of a Gold Nanoparticle–Functionalized Surface Plasmon Resonance Assay for the Sensitive Detection of Monoclonal Antibodies and Its Application in Pharmacokinetics
      You have access
      Development of a Gold Nanoparticle–Functionalized Surface Plasmon Resonance Assay for the Sensitive Detection of Monoclonal Antibodies and Its Application in Pharmacokinetics
      Haihong Bai, Mei Yuan, Xiaojing Wang, Xinghe Wang and Jinjing Che
      Drug Metabolism and Disposition November 2019, 47 (11) 1361-1367; DOI: https://doi.org/10.1124/dmd.119.086249
  5. Wang, Xinghe

    1. Development of a Gold Nanoparticle–Functionalized Surface Plasmon Resonance Assay for the Sensitive Detection of Monoclonal Antibodies and Its Application in Pharmacokinetics
      You have access
      Development of a Gold Nanoparticle–Functionalized Surface Plasmon Resonance Assay for the Sensitive Detection of Monoclonal Antibodies and Its Application in Pharmacokinetics
      Haihong Bai, Mei Yuan, Xiaojing Wang, Xinghe Wang and Jinjing Che
      Drug Metabolism and Disposition November 2019, 47 (11) 1361-1367; DOI: https://doi.org/10.1124/dmd.119.086249
  6. Wang, Zedan

    1. You have access
      Glutathione Conjugation and Protein Adduction Derived from Oxidative Debromination of Benzbromarone in Mice
      Hui Wang, Wenbao Wang, Bowen Gong, Zedan Wang, Yukun Feng, Weige Zhang, Shaojie Wang, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition November 2019, 47 (11) 1281-1290; DOI: https://doi.org/10.1124/dmd.119.087460
  7. Watanabe, Nobuaki

    1. You have access
      Elucidation of N1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters
      Takeshi Miyake, Tadahaya Mizuno, Issey Takehara, Tatsuki Mochizuki, Miyuki Kimura, Shunji Matsuki, Shin Irie, Nobuaki Watanabe, Yukio Kato, Ichiro Ieiri, Kazuya Maeda, Osamu Ando and Hiroyuki Kusuhara
      Drug Metabolism and Disposition November 2019, 47 (11) 1270-1280; DOI: https://doi.org/10.1124/dmd.119.087262
  8. Weidolf, Lars

    1. Metabolism of Strained Rings: Glutathione <em>S</em>-transferase–Catalyzed Formation of a Glutathione-Conjugated Spiro-azetidine without Prior Bioactivation
      You have access
      Metabolism of Strained Rings: Glutathione S-transferase–Catalyzed Formation of a Glutathione-Conjugated Spiro-azetidine without Prior Bioactivation
      Xue-Qing Li, Gunnar Grönberg, Eva-Henriette Bangur, Martin A. Hayes, Neal Castagnoli and Lars Weidolf
      Drug Metabolism and Disposition November 2019, 47 (11) 1247-1256; DOI: https://doi.org/10.1124/dmd.119.088658
  9. Wines, Kahari J.

    1. You have access
      Interindividual Variation in CYP3A Activity Influences Lapatinib Bioactivation
      Jennifer E. Bissada, Vivian Truong, Arsany A. Abouda, Kahari J. Wines, Rachel D. Crouch and Klarissa D. Jackson
      Drug Metabolism and Disposition November 2019, 47 (11) 1257-1269; DOI: https://doi.org/10.1124/dmd.119.088823
  10. Wu, Baojian

    1. You have access
      The Molecular Mechanism Regulating Diurnal Rhythm of Flavin-Containing Monooxygenase 5 in Mouse Liver
      Min Chen, Baozhang Guan, Haiman Xu, Fangjun Yu, Tianpeng Zhang and Baojian Wu
      Drug Metabolism and Disposition November 2019, 47 (11) 1333-1342; DOI: https://doi.org/10.1124/dmd.119.088450

X

  1. Xiao, Yi

    1. You have access
      A Role for the Orphan Human Cytochrome P450 2S1 in Polyunsaturated Fatty Acid ω-1 Hydroxylation Using an Untargeted Metabolomic Approach
      Mostafa I. Fekry, Yi Xiao, Jeannette Zinggeler Berg and F. Peter Guengerich
      Drug Metabolism and Disposition November 2019, 47 (11) 1325-1332; DOI: https://doi.org/10.1124/dmd.119.089086
  2. Xiong, Hui

    1. You have access
      Glucocorticoids Increase Renal Excretion of Urate in Mice by Downregulating Urate Transporter 1
      Gentao Li, Lifeng Han, Ruicong Ma, Khawar Saeed, Hui Xiong, Curtis D. Klaassen, Yuanfu Lu and Youcai Zhang
      Drug Metabolism and Disposition November 2019, 47 (11) 1343-1351; DOI: https://doi.org/10.1124/dmd.119.087700
  3. Xu, Haiman

    1. You have access
      The Molecular Mechanism Regulating Diurnal Rhythm of Flavin-Containing Monooxygenase 5 in Mouse Liver
      Min Chen, Baozhang Guan, Haiman Xu, Fangjun Yu, Tianpeng Zhang and Baojian Wu
      Drug Metabolism and Disposition November 2019, 47 (11) 1333-1342; DOI: https://doi.org/10.1124/dmd.119.088450

Y

  1. Yu, Fangjun

    1. You have access
      The Molecular Mechanism Regulating Diurnal Rhythm of Flavin-Containing Monooxygenase 5 in Mouse Liver
      Min Chen, Baozhang Guan, Haiman Xu, Fangjun Yu, Tianpeng Zhang and Baojian Wu
      Drug Metabolism and Disposition November 2019, 47 (11) 1333-1342; DOI: https://doi.org/10.1124/dmd.119.088450
  2. Yuan, Mei

    1. Development of a Gold Nanoparticle–Functionalized Surface Plasmon Resonance Assay for the Sensitive Detection of Monoclonal Antibodies and Its Application in Pharmacokinetics
      You have access
      Development of a Gold Nanoparticle–Functionalized Surface Plasmon Resonance Assay for the Sensitive Detection of Monoclonal Antibodies and Its Application in Pharmacokinetics
      Haihong Bai, Mei Yuan, Xiaojing Wang, Xinghe Wang and Jinjing Che
      Drug Metabolism and Disposition November 2019, 47 (11) 1361-1367; DOI: https://doi.org/10.1124/dmd.119.086249

Z

  1. Zhang, Tianpeng

    1. You have access
      The Molecular Mechanism Regulating Diurnal Rhythm of Flavin-Containing Monooxygenase 5 in Mouse Liver
      Min Chen, Baozhang Guan, Haiman Xu, Fangjun Yu, Tianpeng Zhang and Baojian Wu
      Drug Metabolism and Disposition November 2019, 47 (11) 1333-1342; DOI: https://doi.org/10.1124/dmd.119.088450
  2. Zhang, Weige

    1. You have access
      Glutathione Conjugation and Protein Adduction Derived from Oxidative Debromination of Benzbromarone in Mice
      Hui Wang, Wenbao Wang, Bowen Gong, Zedan Wang, Yukun Feng, Weige Zhang, Shaojie Wang, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition November 2019, 47 (11) 1281-1290; DOI: https://doi.org/10.1124/dmd.119.087460
  3. Zhang, Youcai

    1. You have access
      Glucocorticoids Increase Renal Excretion of Urate in Mice by Downregulating Urate Transporter 1
      Gentao Li, Lifeng Han, Ruicong Ma, Khawar Saeed, Hui Xiong, Curtis D. Klaassen, Yuanfu Lu and Youcai Zhang
      Drug Metabolism and Disposition November 2019, 47 (11) 1343-1351; DOI: https://doi.org/10.1124/dmd.119.087700
  4. Zhang, Yueping

    1. You have access
      Enhanced and Persistent Inhibition of Organic Cation Transporter 1 Activity by Preincubation of Cyclosporine A
      Erika Panfen, Weiqi Chen, Yueping Zhang, Michael Sinz, Punit Marathe, Jinping Gan and Hong Shen
      Drug Metabolism and Disposition November 2019, 47 (11) 1352-1360; DOI: https://doi.org/10.1124/dmd.119.087197
  5. Zheng, Jiang

    1. You have access
      Glutathione Conjugation and Protein Adduction Derived from Oxidative Debromination of Benzbromarone in Mice
      Hui Wang, Wenbao Wang, Bowen Gong, Zedan Wang, Yukun Feng, Weige Zhang, Shaojie Wang, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition November 2019, 47 (11) 1281-1290; DOI: https://doi.org/10.1124/dmd.119.087460
  6. Zhu, Hao-Jie

    1. You have access
      Absolute Quantitation of Drug-Metabolizing Cytochrome P450 Enzymes and Accessory Proteins in Dog Liver Microsomes Using Label-Free Standard-Free Analysis Reveals Interbreed Variability
      Stephanie E. Martinez, Jian Shi, Hao-Jie Zhu, Tania E. Perez Jimenez, Zhaohui Zhu and Michael H. Court
      Drug Metabolism and Disposition November 2019, 47 (11) 1314-1324; DOI: https://doi.org/10.1124/dmd.119.088070
  7. Zhu, Zhaohui

    1. You have access
      Absolute Quantitation of Drug-Metabolizing Cytochrome P450 Enzymes and Accessory Proteins in Dog Liver Microsomes Using Label-Free Standard-Free Analysis Reveals Interbreed Variability
      Stephanie E. Martinez, Jian Shi, Hao-Jie Zhu, Tania E. Perez Jimenez, Zhaohui Zhu and Michael H. Court
      Drug Metabolism and Disposition November 2019, 47 (11) 1314-1324; DOI: https://doi.org/10.1124/dmd.119.088070
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Drug Metabolism and Disposition: 47 (11)
Drug Metabolism and Disposition
Vol. 47, Issue 11
1 Nov 2019
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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