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Research ArticleArticle

Development of a Gold Nanoparticle–Functionalized Surface Plasmon Resonance Assay for the Sensitive Detection of Monoclonal Antibodies and Its Application in Pharmacokinetics

Haihong Bai, Mei Yuan, Xiaojing Wang, Xinghe Wang and Jinjing Che
Drug Metabolism and Disposition November 2019, 47 (11) 1361-1367; DOI: https://doi.org/10.1124/dmd.119.086249
Haihong Bai
Phase I Clinical Trial Center, Beijing Shijitan Hospital of Capital Medical University, Beijing, PR China (H.B., Xin.W.); State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, PR China (M.Y., J.C.); and Chinese Pharmaceutical Association, Beijing, PR China (Xia.W.)
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Mei Yuan
Phase I Clinical Trial Center, Beijing Shijitan Hospital of Capital Medical University, Beijing, PR China (H.B., Xin.W.); State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, PR China (M.Y., J.C.); and Chinese Pharmaceutical Association, Beijing, PR China (Xia.W.)
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Xiaojing Wang
Phase I Clinical Trial Center, Beijing Shijitan Hospital of Capital Medical University, Beijing, PR China (H.B., Xin.W.); State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, PR China (M.Y., J.C.); and Chinese Pharmaceutical Association, Beijing, PR China (Xia.W.)
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Xinghe Wang
Phase I Clinical Trial Center, Beijing Shijitan Hospital of Capital Medical University, Beijing, PR China (H.B., Xin.W.); State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, PR China (M.Y., J.C.); and Chinese Pharmaceutical Association, Beijing, PR China (Xia.W.)
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Jinjing Che
Phase I Clinical Trial Center, Beijing Shijitan Hospital of Capital Medical University, Beijing, PR China (H.B., Xin.W.); State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, PR China (M.Y., J.C.); and Chinese Pharmaceutical Association, Beijing, PR China (Xia.W.)
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Article Information

vol. 47 no. 11 1361-1367
DOI 
https://doi.org/10.1124/dmd.119.086249
PubMed 
31324700

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received February 9, 2019
  • Accepted July 15, 2019
  • Published online October 22, 2019.

Article Versions

  • Earlier version (July 19, 2019 - 06:00).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2019 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Haihong Bai,
  2. Mei Yuan,
  3. Xiaojing Wang,
  4. Xinghe Wang1, and
  5. Jinjing Che1
  1. Phase I Clinical Trial Center, Beijing Shijitan Hospital of Capital Medical University, Beijing, PR China (H.B., Xin.W.); State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, PR China (M.Y., J.C.); and Chinese Pharmaceutical Association, Beijing, PR China (Xia.W.)
  1. Address correspondence to:
    Jinjing Che, State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, No. 27 Taiping Road, Haidian Distrct, Beijing 100085, China. E-mail: chejinjing80{at}126.com
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Drug Metabolism and Disposition: 47 (11)
Drug Metabolism and Disposition
Vol. 47, Issue 11
1 Nov 2019
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Research ArticleArticle

Au-NP SPR for Pharmacokinetics

Haihong Bai, Mei Yuan, Xiaojing Wang, Xinghe Wang and Jinjing Che
Drug Metabolism and Disposition November 1, 2019, 47 (11) 1361-1367; DOI: https://doi.org/10.1124/dmd.119.086249

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Research ArticleArticle

Au-NP SPR for Pharmacokinetics

Haihong Bai, Mei Yuan, Xiaojing Wang, Xinghe Wang and Jinjing Che
Drug Metabolism and Disposition November 1, 2019, 47 (11) 1361-1367; DOI: https://doi.org/10.1124/dmd.119.086249
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