Index by author
February 01, 2019; Volume 47,Issue 2
A
Anitha, Mallappa
- You have accessBerberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor ActivationYuan Tian, Jingwei Cai, Wei Gui, Robert G. Nichols, Imhoi Koo, Jingtao Zhang, Mallappa Anitha and Andrew D. PattersonDrug Metabolism and Disposition February 2019, 47 (2) 86-93; DOI: https://doi.org/10.1124/dmd.118.083691
B
Badée, Justine
- You have accessOptimization of Experimental Conditions of Automated Glucuronidation Assays in Human Liver Microsomes Using a Cocktail Approach and Ultra-High Performance Liquid Chromatography–Tandem Mass SpectrometryJustine Badée, Nahong Qiu, Neil Parrott, Abby C. Collier, Stephan Schmidt and Stephen FowlerDrug Metabolism and Disposition February 2019, 47 (2) 124-134; DOI: https://doi.org/10.1124/dmd.118.084301
Beaudoin, James J.
- You have accessAltered Hepatobiliary Disposition of Tolvaptan and Selected Tolvaptan Metabolites in a Rodent Model of Polycystic Kidney DiseaseJames J. Beaudoin, Jacqueline Bezençon, Yanguang Cao, Katsuhiko Mizuno, Sharin E. Roth, William J. Brock and Kim L. R. BrouwerDrug Metabolism and Disposition February 2019, 47 (2) 155-163; DOI: https://doi.org/10.1124/dmd.118.083907
Bezençon, Jacqueline
- You have accessAltered Hepatobiliary Disposition of Tolvaptan and Selected Tolvaptan Metabolites in a Rodent Model of Polycystic Kidney DiseaseJames J. Beaudoin, Jacqueline Bezençon, Yanguang Cao, Katsuhiko Mizuno, Sharin E. Roth, William J. Brock and Kim L. R. BrouwerDrug Metabolism and Disposition February 2019, 47 (2) 155-163; DOI: https://doi.org/10.1124/dmd.118.083907
Bibikova, Elena
- Open AccessBioavailability, Biotransformation, and Excretion of the Covalent Bruton Tyrosine Kinase Inhibitor Acalabrutinib in Rats, Dogs, and HumansTerry Podoll, Paul G. Pearson, Jerry Evarts, Tim Ingallinera, Elena Bibikova, Hao Sun, Mark Gohdes, Kristen Cardinal, Mitesh Sanghvi and J. Greg SlatterDrug Metabolism and Disposition February 2019, 47 (2) 145-154; DOI: https://doi.org/10.1124/dmd.118.084459
Brock, William J.
- You have accessAltered Hepatobiliary Disposition of Tolvaptan and Selected Tolvaptan Metabolites in a Rodent Model of Polycystic Kidney DiseaseJames J. Beaudoin, Jacqueline Bezençon, Yanguang Cao, Katsuhiko Mizuno, Sharin E. Roth, William J. Brock and Kim L. R. BrouwerDrug Metabolism and Disposition February 2019, 47 (2) 155-163; DOI: https://doi.org/10.1124/dmd.118.083907
Bromek, Ewa
- You have accessSerotonin Receptors of 5-HT2 Type in the Hypothalamic Arcuate Nuclei Positively Regulate Liver Cytochrome P450 via Stimulation of the Growth Hormone–Releasing Hormone/Growth Hormone Hormonal PathwayEwa Bromek, Marta Rysz, Anna Haduch and Władysława A. DanielDrug Metabolism and Disposition February 2019, 47 (2) 80-85; DOI: https://doi.org/10.1124/dmd.118.083808
Brouwer, Kim L. R.
- You have accessAltered Hepatobiliary Disposition of Tolvaptan and Selected Tolvaptan Metabolites in a Rodent Model of Polycystic Kidney DiseaseJames J. Beaudoin, Jacqueline Bezençon, Yanguang Cao, Katsuhiko Mizuno, Sharin E. Roth, William J. Brock and Kim L. R. BrouwerDrug Metabolism and Disposition February 2019, 47 (2) 155-163; DOI: https://doi.org/10.1124/dmd.118.083907
C
Cai, Jingwei
- You have accessBerberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor ActivationYuan Tian, Jingwei Cai, Wei Gui, Robert G. Nichols, Imhoi Koo, Jingtao Zhang, Mallappa Anitha and Andrew D. PattersonDrug Metabolism and Disposition February 2019, 47 (2) 86-93; DOI: https://doi.org/10.1124/dmd.118.083691
Callaghan, Richard
- You have accessOvercoming P-Glycoprotein–Mediated Drug Resistance with Noscapine DerivativesDivya Muthiah, Georgia K. Henshaw, Aaron J. DeBono, Ben Capuano, Peter J. Scammells and Richard CallaghanDrug Metabolism and Disposition February 2019, 47 (2) 164-172; DOI: https://doi.org/10.1124/dmd.118.083188
Cao, Yanguang
- You have accessAltered Hepatobiliary Disposition of Tolvaptan and Selected Tolvaptan Metabolites in a Rodent Model of Polycystic Kidney DiseaseJames J. Beaudoin, Jacqueline Bezençon, Yanguang Cao, Katsuhiko Mizuno, Sharin E. Roth, William J. Brock and Kim L. R. BrouwerDrug Metabolism and Disposition February 2019, 47 (2) 155-163; DOI: https://doi.org/10.1124/dmd.118.083907
Capuano, Ben
- You have accessOvercoming P-Glycoprotein–Mediated Drug Resistance with Noscapine DerivativesDivya Muthiah, Georgia K. Henshaw, Aaron J. DeBono, Ben Capuano, Peter J. Scammells and Richard CallaghanDrug Metabolism and Disposition February 2019, 47 (2) 164-172; DOI: https://doi.org/10.1124/dmd.118.083188
Cardinal, Kristen
- Open AccessBioavailability, Biotransformation, and Excretion of the Covalent Bruton Tyrosine Kinase Inhibitor Acalabrutinib in Rats, Dogs, and HumansTerry Podoll, Paul G. Pearson, Jerry Evarts, Tim Ingallinera, Elena Bibikova, Hao Sun, Mark Gohdes, Kristen Cardinal, Mitesh Sanghvi and J. Greg SlatterDrug Metabolism and Disposition February 2019, 47 (2) 145-154; DOI: https://doi.org/10.1124/dmd.118.084459
Collier, Abby C.
- You have accessOptimization of Experimental Conditions of Automated Glucuronidation Assays in Human Liver Microsomes Using a Cocktail Approach and Ultra-High Performance Liquid Chromatography–Tandem Mass SpectrometryJustine Badée, Nahong Qiu, Neil Parrott, Abby C. Collier, Stephan Schmidt and Stephen FowlerDrug Metabolism and Disposition February 2019, 47 (2) 124-134; DOI: https://doi.org/10.1124/dmd.118.084301
D
Daniel, Władysława A.
- You have accessSerotonin Receptors of 5-HT2 Type in the Hypothalamic Arcuate Nuclei Positively Regulate Liver Cytochrome P450 via Stimulation of the Growth Hormone–Releasing Hormone/Growth Hormone Hormonal PathwayEwa Bromek, Marta Rysz, Anna Haduch and Władysława A. DanielDrug Metabolism and Disposition February 2019, 47 (2) 80-85; DOI: https://doi.org/10.1124/dmd.118.083808
DeBono, Aaron J.
- You have accessOvercoming P-Glycoprotein–Mediated Drug Resistance with Noscapine DerivativesDivya Muthiah, Georgia K. Henshaw, Aaron J. DeBono, Ben Capuano, Peter J. Scammells and Richard CallaghanDrug Metabolism and Disposition February 2019, 47 (2) 164-172; DOI: https://doi.org/10.1124/dmd.118.083188
E
El-Kadi, Ayman O. S.
- You have accessIdentification of 19-(S/R)Hydroxyeicosatetraenoic Acid as the First Endogenous Noncompetitive Inhibitor of Cytochrome P450 1B1 with Enantioselective ActivitySherif M. Shoieb, Ahmed A. El-Sherbeni and Ayman O. S. El-KadiDrug Metabolism and Disposition February 2019, 47 (2) 67-70; DOI: https://doi.org/10.1124/dmd.118.084657
El-Sherbeni, Ahmed A.
- You have accessIdentification of 19-(S/R)Hydroxyeicosatetraenoic Acid as the First Endogenous Noncompetitive Inhibitor of Cytochrome P450 1B1 with Enantioselective ActivitySherif M. Shoieb, Ahmed A. El-Sherbeni and Ayman O. S. El-KadiDrug Metabolism and Disposition February 2019, 47 (2) 67-70; DOI: https://doi.org/10.1124/dmd.118.084657
Evarts, Jerry
- Open AccessBioavailability, Biotransformation, and Excretion of the Covalent Bruton Tyrosine Kinase Inhibitor Acalabrutinib in Rats, Dogs, and HumansTerry Podoll, Paul G. Pearson, Jerry Evarts, Tim Ingallinera, Elena Bibikova, Hao Sun, Mark Gohdes, Kristen Cardinal, Mitesh Sanghvi and J. Greg SlatterDrug Metabolism and Disposition February 2019, 47 (2) 145-154; DOI: https://doi.org/10.1124/dmd.118.084459
F
Fowler, Stephen
- You have accessOptimization of Experimental Conditions of Automated Glucuronidation Assays in Human Liver Microsomes Using a Cocktail Approach and Ultra-High Performance Liquid Chromatography–Tandem Mass SpectrometryJustine Badée, Nahong Qiu, Neil Parrott, Abby C. Collier, Stephan Schmidt and Stephen FowlerDrug Metabolism and Disposition February 2019, 47 (2) 124-134; DOI: https://doi.org/10.1124/dmd.118.084301
G
Girardet, Jean-Luc
- You have accessCharacterization of Stereoselective Metabolism, Inhibitory Effect on Uric Acid Uptake Transporters, and Pharmacokinetics of Lesinurad AtropisomersChun Yang, Dongmei Zhou, Zancong Shen, David M. Wilson, Matthew Renner, Jeffrey N. Miner, Jean-Luc Girardet and Caroline A. LeeDrug Metabolism and Disposition February 2019, 47 (2) 104-113; DOI: https://doi.org/10.1124/dmd.118.080549
Gohdes, Mark
- Open AccessBioavailability, Biotransformation, and Excretion of the Covalent Bruton Tyrosine Kinase Inhibitor Acalabrutinib in Rats, Dogs, and HumansTerry Podoll, Paul G. Pearson, Jerry Evarts, Tim Ingallinera, Elena Bibikova, Hao Sun, Mark Gohdes, Kristen Cardinal, Mitesh Sanghvi and J. Greg SlatterDrug Metabolism and Disposition February 2019, 47 (2) 145-154; DOI: https://doi.org/10.1124/dmd.118.084459
Gui, Wei
- You have accessBerberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor ActivationYuan Tian, Jingwei Cai, Wei Gui, Robert G. Nichols, Imhoi Koo, Jingtao Zhang, Mallappa Anitha and Andrew D. PattersonDrug Metabolism and Disposition February 2019, 47 (2) 86-93; DOI: https://doi.org/10.1124/dmd.118.083691
H
Haduch, Anna
- You have accessSerotonin Receptors of 5-HT2 Type in the Hypothalamic Arcuate Nuclei Positively Regulate Liver Cytochrome P450 via Stimulation of the Growth Hormone–Releasing Hormone/Growth Hormone Hormonal PathwayEwa Bromek, Marta Rysz, Anna Haduch and Władysława A. DanielDrug Metabolism and Disposition February 2019, 47 (2) 80-85; DOI: https://doi.org/10.1124/dmd.118.083808
Henshaw, Georgia K.
- You have accessOvercoming P-Glycoprotein–Mediated Drug Resistance with Noscapine DerivativesDivya Muthiah, Georgia K. Henshaw, Aaron J. DeBono, Ben Capuano, Peter J. Scammells and Richard CallaghanDrug Metabolism and Disposition February 2019, 47 (2) 164-172; DOI: https://doi.org/10.1124/dmd.118.083188
I
Ingallinera, Tim
- Open AccessBioavailability, Biotransformation, and Excretion of the Covalent Bruton Tyrosine Kinase Inhibitor Acalabrutinib in Rats, Dogs, and HumansTerry Podoll, Paul G. Pearson, Jerry Evarts, Tim Ingallinera, Elena Bibikova, Hao Sun, Mark Gohdes, Kristen Cardinal, Mitesh Sanghvi and J. Greg SlatterDrug Metabolism and Disposition February 2019, 47 (2) 145-154; DOI: https://doi.org/10.1124/dmd.118.084459
K
Kim, Soo-Jin
- You have accessExtrapolation of In Vivo Hepatic Clearance from In Vitro Uptake Clearance by Suspended Human Hepatocytes for Anionic Drugs with High Binding to Human Albumin: Improvement of In Vitro-to-In Vivo Extrapolation by Considering the “Albumin-Mediated” Hepatic Uptake Mechanism on the Basis of the “Facilitated-Dissociation Model”Soo-Jin Kim, Kyeong-Ryoon Lee, Seiji Miyauchi and Yuichi SugiyamaDrug Metabolism and Disposition February 2019, 47 (2) 94-103; DOI: https://doi.org/10.1124/dmd.118.083733
Kojima, Koki
- You have accessPrediction of Human Distribution Volumes of Compounds in Various Elimination Phases Using Physiologically Based Pharmacokinetic Modeling and Experimental Pharmacokinetics in AnimalsHidetoshi Shimizu, Kosuke Yoshida, Tomohisa Nakada, Koki Kojima, Akihito Ogasawara, Yoshinobu Nakamaru and Hiroshi YamazakiDrug Metabolism and Disposition February 2019, 47 (2) 114-123; DOI: https://doi.org/10.1124/dmd.118.083642
Koo, Imhoi
- You have accessBerberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor ActivationYuan Tian, Jingwei Cai, Wei Gui, Robert G. Nichols, Imhoi Koo, Jingtao Zhang, Mallappa Anitha and Andrew D. PattersonDrug Metabolism and Disposition February 2019, 47 (2) 86-93; DOI: https://doi.org/10.1124/dmd.118.083691
L
Lee, Caroline A.
- You have accessCharacterization of Stereoselective Metabolism, Inhibitory Effect on Uric Acid Uptake Transporters, and Pharmacokinetics of Lesinurad AtropisomersChun Yang, Dongmei Zhou, Zancong Shen, David M. Wilson, Matthew Renner, Jeffrey N. Miner, Jean-Luc Girardet and Caroline A. LeeDrug Metabolism and Disposition February 2019, 47 (2) 104-113; DOI: https://doi.org/10.1124/dmd.118.080549
Lee, Kyeong-Ryoon
- You have accessExtrapolation of In Vivo Hepatic Clearance from In Vitro Uptake Clearance by Suspended Human Hepatocytes for Anionic Drugs with High Binding to Human Albumin: Improvement of In Vitro-to-In Vivo Extrapolation by Considering the “Albumin-Mediated” Hepatic Uptake Mechanism on the Basis of the “Facilitated-Dissociation Model”Soo-Jin Kim, Kyeong-Ryoon Lee, Seiji Miyauchi and Yuichi SugiyamaDrug Metabolism and Disposition February 2019, 47 (2) 94-103; DOI: https://doi.org/10.1124/dmd.118.083733
Levy, René H.
- You have accessMechanisms and Clinical Significance of Pharmacokinetic-Based Drug-Drug Interactions with Drugs Approved by the U.S. Food and Drug Administration in 2017Jingjing Yu, Ichiko D. Petrie, René H. Levy and Isabelle Ragueneau-MajlessiDrug Metabolism and Disposition February 2019, 47 (2) 135-144; DOI: https://doi.org/10.1124/dmd.118.084905
Li, Yongmei
- You have accessDevelopment and Characterization of MDR1 (Mdr1a/b) CRISPR/Cas9 Knockout Rat ModelChenmeizi Liang, Junfang Zhao, Jian Lu, Yuanjin Zhang, Xinrun Ma, Xuyang Shang, Yongmei Li, Xueyun Ma, Mingyao Liu and Xin WangDrug Metabolism and Disposition February 2019, 47 (2) 71-79; DOI: https://doi.org/10.1124/dmd.118.084277
Liang, Chenmeizi
- You have accessDevelopment and Characterization of MDR1 (Mdr1a/b) CRISPR/Cas9 Knockout Rat ModelChenmeizi Liang, Junfang Zhao, Jian Lu, Yuanjin Zhang, Xinrun Ma, Xuyang Shang, Yongmei Li, Xueyun Ma, Mingyao Liu and Xin WangDrug Metabolism and Disposition February 2019, 47 (2) 71-79; DOI: https://doi.org/10.1124/dmd.118.084277
Liu, Mingyao
- You have accessDevelopment and Characterization of MDR1 (Mdr1a/b) CRISPR/Cas9 Knockout Rat ModelChenmeizi Liang, Junfang Zhao, Jian Lu, Yuanjin Zhang, Xinrun Ma, Xuyang Shang, Yongmei Li, Xueyun Ma, Mingyao Liu and Xin WangDrug Metabolism and Disposition February 2019, 47 (2) 71-79; DOI: https://doi.org/10.1124/dmd.118.084277
Lu, Jian
- You have accessDevelopment and Characterization of MDR1 (Mdr1a/b) CRISPR/Cas9 Knockout Rat ModelChenmeizi Liang, Junfang Zhao, Jian Lu, Yuanjin Zhang, Xinrun Ma, Xuyang Shang, Yongmei Li, Xueyun Ma, Mingyao Liu and Xin WangDrug Metabolism and Disposition February 2019, 47 (2) 71-79; DOI: https://doi.org/10.1124/dmd.118.084277
M
Ma, Xinrun
- You have accessDevelopment and Characterization of MDR1 (Mdr1a/b) CRISPR/Cas9 Knockout Rat ModelChenmeizi Liang, Junfang Zhao, Jian Lu, Yuanjin Zhang, Xinrun Ma, Xuyang Shang, Yongmei Li, Xueyun Ma, Mingyao Liu and Xin WangDrug Metabolism and Disposition February 2019, 47 (2) 71-79; DOI: https://doi.org/10.1124/dmd.118.084277
Ma, Xueyun
- You have accessDevelopment and Characterization of MDR1 (Mdr1a/b) CRISPR/Cas9 Knockout Rat ModelChenmeizi Liang, Junfang Zhao, Jian Lu, Yuanjin Zhang, Xinrun Ma, Xuyang Shang, Yongmei Li, Xueyun Ma, Mingyao Liu and Xin WangDrug Metabolism and Disposition February 2019, 47 (2) 71-79; DOI: https://doi.org/10.1124/dmd.118.084277
Miner, Jeffrey N.
- You have accessCharacterization of Stereoselective Metabolism, Inhibitory Effect on Uric Acid Uptake Transporters, and Pharmacokinetics of Lesinurad AtropisomersChun Yang, Dongmei Zhou, Zancong Shen, David M. Wilson, Matthew Renner, Jeffrey N. Miner, Jean-Luc Girardet and Caroline A. LeeDrug Metabolism and Disposition February 2019, 47 (2) 104-113; DOI: https://doi.org/10.1124/dmd.118.080549
Miyauchi, Seiji
- You have accessExtrapolation of In Vivo Hepatic Clearance from In Vitro Uptake Clearance by Suspended Human Hepatocytes for Anionic Drugs with High Binding to Human Albumin: Improvement of In Vitro-to-In Vivo Extrapolation by Considering the “Albumin-Mediated” Hepatic Uptake Mechanism on the Basis of the “Facilitated-Dissociation Model”Soo-Jin Kim, Kyeong-Ryoon Lee, Seiji Miyauchi and Yuichi SugiyamaDrug Metabolism and Disposition February 2019, 47 (2) 94-103; DOI: https://doi.org/10.1124/dmd.118.083733
Mizuno, Katsuhiko
- You have accessAltered Hepatobiliary Disposition of Tolvaptan and Selected Tolvaptan Metabolites in a Rodent Model of Polycystic Kidney DiseaseJames J. Beaudoin, Jacqueline Bezençon, Yanguang Cao, Katsuhiko Mizuno, Sharin E. Roth, William J. Brock and Kim L. R. BrouwerDrug Metabolism and Disposition February 2019, 47 (2) 155-163; DOI: https://doi.org/10.1124/dmd.118.083907
Muthiah, Divya
- You have accessOvercoming P-Glycoprotein–Mediated Drug Resistance with Noscapine DerivativesDivya Muthiah, Georgia K. Henshaw, Aaron J. DeBono, Ben Capuano, Peter J. Scammells and Richard CallaghanDrug Metabolism and Disposition February 2019, 47 (2) 164-172; DOI: https://doi.org/10.1124/dmd.118.083188
N
Nakada, Tomohisa
- You have accessPrediction of Human Distribution Volumes of Compounds in Various Elimination Phases Using Physiologically Based Pharmacokinetic Modeling and Experimental Pharmacokinetics in AnimalsHidetoshi Shimizu, Kosuke Yoshida, Tomohisa Nakada, Koki Kojima, Akihito Ogasawara, Yoshinobu Nakamaru and Hiroshi YamazakiDrug Metabolism and Disposition February 2019, 47 (2) 114-123; DOI: https://doi.org/10.1124/dmd.118.083642
Nakamaru, Yoshinobu
- You have accessPrediction of Human Distribution Volumes of Compounds in Various Elimination Phases Using Physiologically Based Pharmacokinetic Modeling and Experimental Pharmacokinetics in AnimalsHidetoshi Shimizu, Kosuke Yoshida, Tomohisa Nakada, Koki Kojima, Akihito Ogasawara, Yoshinobu Nakamaru and Hiroshi YamazakiDrug Metabolism and Disposition February 2019, 47 (2) 114-123; DOI: https://doi.org/10.1124/dmd.118.083642
Nichols, Robert G.
- You have accessBerberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor ActivationYuan Tian, Jingwei Cai, Wei Gui, Robert G. Nichols, Imhoi Koo, Jingtao Zhang, Mallappa Anitha and Andrew D. PattersonDrug Metabolism and Disposition February 2019, 47 (2) 86-93; DOI: https://doi.org/10.1124/dmd.118.083691
O
Ogasawara, Akihito
- You have accessPrediction of Human Distribution Volumes of Compounds in Various Elimination Phases Using Physiologically Based Pharmacokinetic Modeling and Experimental Pharmacokinetics in AnimalsHidetoshi Shimizu, Kosuke Yoshida, Tomohisa Nakada, Koki Kojima, Akihito Ogasawara, Yoshinobu Nakamaru and Hiroshi YamazakiDrug Metabolism and Disposition February 2019, 47 (2) 114-123; DOI: https://doi.org/10.1124/dmd.118.083642
P
Parrott, Neil
- You have accessOptimization of Experimental Conditions of Automated Glucuronidation Assays in Human Liver Microsomes Using a Cocktail Approach and Ultra-High Performance Liquid Chromatography–Tandem Mass SpectrometryJustine Badée, Nahong Qiu, Neil Parrott, Abby C. Collier, Stephan Schmidt and Stephen FowlerDrug Metabolism and Disposition February 2019, 47 (2) 124-134; DOI: https://doi.org/10.1124/dmd.118.084301
Patterson, Andrew D.
- You have accessBerberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor ActivationYuan Tian, Jingwei Cai, Wei Gui, Robert G. Nichols, Imhoi Koo, Jingtao Zhang, Mallappa Anitha and Andrew D. PattersonDrug Metabolism and Disposition February 2019, 47 (2) 86-93; DOI: https://doi.org/10.1124/dmd.118.083691
Pearson, Paul G.
- Open AccessBioavailability, Biotransformation, and Excretion of the Covalent Bruton Tyrosine Kinase Inhibitor Acalabrutinib in Rats, Dogs, and HumansTerry Podoll, Paul G. Pearson, Jerry Evarts, Tim Ingallinera, Elena Bibikova, Hao Sun, Mark Gohdes, Kristen Cardinal, Mitesh Sanghvi and J. Greg SlatterDrug Metabolism and Disposition February 2019, 47 (2) 145-154; DOI: https://doi.org/10.1124/dmd.118.084459
Petrie, Ichiko D.
- You have accessMechanisms and Clinical Significance of Pharmacokinetic-Based Drug-Drug Interactions with Drugs Approved by the U.S. Food and Drug Administration in 2017Jingjing Yu, Ichiko D. Petrie, René H. Levy and Isabelle Ragueneau-MajlessiDrug Metabolism and Disposition February 2019, 47 (2) 135-144; DOI: https://doi.org/10.1124/dmd.118.084905
Podoll, Terry
- Open AccessBioavailability, Biotransformation, and Excretion of the Covalent Bruton Tyrosine Kinase Inhibitor Acalabrutinib in Rats, Dogs, and HumansTerry Podoll, Paul G. Pearson, Jerry Evarts, Tim Ingallinera, Elena Bibikova, Hao Sun, Mark Gohdes, Kristen Cardinal, Mitesh Sanghvi and J. Greg SlatterDrug Metabolism and Disposition February 2019, 47 (2) 145-154; DOI: https://doi.org/10.1124/dmd.118.084459
Q
Qiu, Nahong
- You have accessOptimization of Experimental Conditions of Automated Glucuronidation Assays in Human Liver Microsomes Using a Cocktail Approach and Ultra-High Performance Liquid Chromatography–Tandem Mass SpectrometryJustine Badée, Nahong Qiu, Neil Parrott, Abby C. Collier, Stephan Schmidt and Stephen FowlerDrug Metabolism and Disposition February 2019, 47 (2) 124-134; DOI: https://doi.org/10.1124/dmd.118.084301
R
Ragueneau-Majlessi, Isabelle
- You have accessMechanisms and Clinical Significance of Pharmacokinetic-Based Drug-Drug Interactions with Drugs Approved by the U.S. Food and Drug Administration in 2017Jingjing Yu, Ichiko D. Petrie, René H. Levy and Isabelle Ragueneau-MajlessiDrug Metabolism and Disposition February 2019, 47 (2) 135-144; DOI: https://doi.org/10.1124/dmd.118.084905
Renner, Matthew
- You have accessCharacterization of Stereoselective Metabolism, Inhibitory Effect on Uric Acid Uptake Transporters, and Pharmacokinetics of Lesinurad AtropisomersChun Yang, Dongmei Zhou, Zancong Shen, David M. Wilson, Matthew Renner, Jeffrey N. Miner, Jean-Luc Girardet and Caroline A. LeeDrug Metabolism and Disposition February 2019, 47 (2) 104-113; DOI: https://doi.org/10.1124/dmd.118.080549
Roth, Sharin E.
- You have accessAltered Hepatobiliary Disposition of Tolvaptan and Selected Tolvaptan Metabolites in a Rodent Model of Polycystic Kidney DiseaseJames J. Beaudoin, Jacqueline Bezençon, Yanguang Cao, Katsuhiko Mizuno, Sharin E. Roth, William J. Brock and Kim L. R. BrouwerDrug Metabolism and Disposition February 2019, 47 (2) 155-163; DOI: https://doi.org/10.1124/dmd.118.083907
Rysz, Marta
- You have accessSerotonin Receptors of 5-HT2 Type in the Hypothalamic Arcuate Nuclei Positively Regulate Liver Cytochrome P450 via Stimulation of the Growth Hormone–Releasing Hormone/Growth Hormone Hormonal PathwayEwa Bromek, Marta Rysz, Anna Haduch and Władysława A. DanielDrug Metabolism and Disposition February 2019, 47 (2) 80-85; DOI: https://doi.org/10.1124/dmd.118.083808
S
Sanghvi, Mitesh
- Open AccessBioavailability, Biotransformation, and Excretion of the Covalent Bruton Tyrosine Kinase Inhibitor Acalabrutinib in Rats, Dogs, and HumansTerry Podoll, Paul G. Pearson, Jerry Evarts, Tim Ingallinera, Elena Bibikova, Hao Sun, Mark Gohdes, Kristen Cardinal, Mitesh Sanghvi and J. Greg SlatterDrug Metabolism and Disposition February 2019, 47 (2) 145-154; DOI: https://doi.org/10.1124/dmd.118.084459
Scammells, Peter J.
- You have accessOvercoming P-Glycoprotein–Mediated Drug Resistance with Noscapine DerivativesDivya Muthiah, Georgia K. Henshaw, Aaron J. DeBono, Ben Capuano, Peter J. Scammells and Richard CallaghanDrug Metabolism and Disposition February 2019, 47 (2) 164-172; DOI: https://doi.org/10.1124/dmd.118.083188
Schmidt, Stephan
- You have accessOptimization of Experimental Conditions of Automated Glucuronidation Assays in Human Liver Microsomes Using a Cocktail Approach and Ultra-High Performance Liquid Chromatography–Tandem Mass SpectrometryJustine Badée, Nahong Qiu, Neil Parrott, Abby C. Collier, Stephan Schmidt and Stephen FowlerDrug Metabolism and Disposition February 2019, 47 (2) 124-134; DOI: https://doi.org/10.1124/dmd.118.084301
Shang, Xuyang
- You have accessDevelopment and Characterization of MDR1 (Mdr1a/b) CRISPR/Cas9 Knockout Rat ModelChenmeizi Liang, Junfang Zhao, Jian Lu, Yuanjin Zhang, Xinrun Ma, Xuyang Shang, Yongmei Li, Xueyun Ma, Mingyao Liu and Xin WangDrug Metabolism and Disposition February 2019, 47 (2) 71-79; DOI: https://doi.org/10.1124/dmd.118.084277
Shen, Zancong
- You have accessCharacterization of Stereoselective Metabolism, Inhibitory Effect on Uric Acid Uptake Transporters, and Pharmacokinetics of Lesinurad AtropisomersChun Yang, Dongmei Zhou, Zancong Shen, David M. Wilson, Matthew Renner, Jeffrey N. Miner, Jean-Luc Girardet and Caroline A. LeeDrug Metabolism and Disposition February 2019, 47 (2) 104-113; DOI: https://doi.org/10.1124/dmd.118.080549
Shimizu, Hidetoshi
- You have accessPrediction of Human Distribution Volumes of Compounds in Various Elimination Phases Using Physiologically Based Pharmacokinetic Modeling and Experimental Pharmacokinetics in AnimalsHidetoshi Shimizu, Kosuke Yoshida, Tomohisa Nakada, Koki Kojima, Akihito Ogasawara, Yoshinobu Nakamaru and Hiroshi YamazakiDrug Metabolism and Disposition February 2019, 47 (2) 114-123; DOI: https://doi.org/10.1124/dmd.118.083642
Shoieb, Sherif M.
- You have accessIdentification of 19-(S/R)Hydroxyeicosatetraenoic Acid as the First Endogenous Noncompetitive Inhibitor of Cytochrome P450 1B1 with Enantioselective ActivitySherif M. Shoieb, Ahmed A. El-Sherbeni and Ayman O. S. El-KadiDrug Metabolism and Disposition February 2019, 47 (2) 67-70; DOI: https://doi.org/10.1124/dmd.118.084657
Slatter, J. Greg
- Open AccessBioavailability, Biotransformation, and Excretion of the Covalent Bruton Tyrosine Kinase Inhibitor Acalabrutinib in Rats, Dogs, and HumansTerry Podoll, Paul G. Pearson, Jerry Evarts, Tim Ingallinera, Elena Bibikova, Hao Sun, Mark Gohdes, Kristen Cardinal, Mitesh Sanghvi and J. Greg SlatterDrug Metabolism and Disposition February 2019, 47 (2) 145-154; DOI: https://doi.org/10.1124/dmd.118.084459
Sugiyama, Yuichi
- You have accessExtrapolation of In Vivo Hepatic Clearance from In Vitro Uptake Clearance by Suspended Human Hepatocytes for Anionic Drugs with High Binding to Human Albumin: Improvement of In Vitro-to-In Vivo Extrapolation by Considering the “Albumin-Mediated” Hepatic Uptake Mechanism on the Basis of the “Facilitated-Dissociation Model”Soo-Jin Kim, Kyeong-Ryoon Lee, Seiji Miyauchi and Yuichi SugiyamaDrug Metabolism and Disposition February 2019, 47 (2) 94-103; DOI: https://doi.org/10.1124/dmd.118.083733
Sun, Hao
- Open AccessBioavailability, Biotransformation, and Excretion of the Covalent Bruton Tyrosine Kinase Inhibitor Acalabrutinib in Rats, Dogs, and HumansTerry Podoll, Paul G. Pearson, Jerry Evarts, Tim Ingallinera, Elena Bibikova, Hao Sun, Mark Gohdes, Kristen Cardinal, Mitesh Sanghvi and J. Greg SlatterDrug Metabolism and Disposition February 2019, 47 (2) 145-154; DOI: https://doi.org/10.1124/dmd.118.084459
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Tian, Yuan
- You have accessBerberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor ActivationYuan Tian, Jingwei Cai, Wei Gui, Robert G. Nichols, Imhoi Koo, Jingtao Zhang, Mallappa Anitha and Andrew D. PattersonDrug Metabolism and Disposition February 2019, 47 (2) 86-93; DOI: https://doi.org/10.1124/dmd.118.083691
W
Wang, Xin
- You have accessDevelopment and Characterization of MDR1 (Mdr1a/b) CRISPR/Cas9 Knockout Rat ModelChenmeizi Liang, Junfang Zhao, Jian Lu, Yuanjin Zhang, Xinrun Ma, Xuyang Shang, Yongmei Li, Xueyun Ma, Mingyao Liu and Xin WangDrug Metabolism and Disposition February 2019, 47 (2) 71-79; DOI: https://doi.org/10.1124/dmd.118.084277
Wilson, David M.
- You have accessCharacterization of Stereoselective Metabolism, Inhibitory Effect on Uric Acid Uptake Transporters, and Pharmacokinetics of Lesinurad AtropisomersChun Yang, Dongmei Zhou, Zancong Shen, David M. Wilson, Matthew Renner, Jeffrey N. Miner, Jean-Luc Girardet and Caroline A. LeeDrug Metabolism and Disposition February 2019, 47 (2) 104-113; DOI: https://doi.org/10.1124/dmd.118.080549
Y
Yamazaki, Hiroshi
- You have accessPrediction of Human Distribution Volumes of Compounds in Various Elimination Phases Using Physiologically Based Pharmacokinetic Modeling and Experimental Pharmacokinetics in AnimalsHidetoshi Shimizu, Kosuke Yoshida, Tomohisa Nakada, Koki Kojima, Akihito Ogasawara, Yoshinobu Nakamaru and Hiroshi YamazakiDrug Metabolism and Disposition February 2019, 47 (2) 114-123; DOI: https://doi.org/10.1124/dmd.118.083642
Yang, Chun
- You have accessCharacterization of Stereoselective Metabolism, Inhibitory Effect on Uric Acid Uptake Transporters, and Pharmacokinetics of Lesinurad AtropisomersChun Yang, Dongmei Zhou, Zancong Shen, David M. Wilson, Matthew Renner, Jeffrey N. Miner, Jean-Luc Girardet and Caroline A. LeeDrug Metabolism and Disposition February 2019, 47 (2) 104-113; DOI: https://doi.org/10.1124/dmd.118.080549
Yoshida, Kosuke
- You have accessPrediction of Human Distribution Volumes of Compounds in Various Elimination Phases Using Physiologically Based Pharmacokinetic Modeling and Experimental Pharmacokinetics in AnimalsHidetoshi Shimizu, Kosuke Yoshida, Tomohisa Nakada, Koki Kojima, Akihito Ogasawara, Yoshinobu Nakamaru and Hiroshi YamazakiDrug Metabolism and Disposition February 2019, 47 (2) 114-123; DOI: https://doi.org/10.1124/dmd.118.083642
Yu, Jingjing
- You have accessMechanisms and Clinical Significance of Pharmacokinetic-Based Drug-Drug Interactions with Drugs Approved by the U.S. Food and Drug Administration in 2017Jingjing Yu, Ichiko D. Petrie, René H. Levy and Isabelle Ragueneau-MajlessiDrug Metabolism and Disposition February 2019, 47 (2) 135-144; DOI: https://doi.org/10.1124/dmd.118.084905
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Zhang, Jingtao
- You have accessBerberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor ActivationYuan Tian, Jingwei Cai, Wei Gui, Robert G. Nichols, Imhoi Koo, Jingtao Zhang, Mallappa Anitha and Andrew D. PattersonDrug Metabolism and Disposition February 2019, 47 (2) 86-93; DOI: https://doi.org/10.1124/dmd.118.083691
Zhang, Yuanjin
- You have accessDevelopment and Characterization of MDR1 (Mdr1a/b) CRISPR/Cas9 Knockout Rat ModelChenmeizi Liang, Junfang Zhao, Jian Lu, Yuanjin Zhang, Xinrun Ma, Xuyang Shang, Yongmei Li, Xueyun Ma, Mingyao Liu and Xin WangDrug Metabolism and Disposition February 2019, 47 (2) 71-79; DOI: https://doi.org/10.1124/dmd.118.084277
Zhao, Junfang
- You have accessDevelopment and Characterization of MDR1 (Mdr1a/b) CRISPR/Cas9 Knockout Rat ModelChenmeizi Liang, Junfang Zhao, Jian Lu, Yuanjin Zhang, Xinrun Ma, Xuyang Shang, Yongmei Li, Xueyun Ma, Mingyao Liu and Xin WangDrug Metabolism and Disposition February 2019, 47 (2) 71-79; DOI: https://doi.org/10.1124/dmd.118.084277
Zhou, Dongmei
- You have accessCharacterization of Stereoselective Metabolism, Inhibitory Effect on Uric Acid Uptake Transporters, and Pharmacokinetics of Lesinurad AtropisomersChun Yang, Dongmei Zhou, Zancong Shen, David M. Wilson, Matthew Renner, Jeffrey N. Miner, Jean-Luc Girardet and Caroline A. LeeDrug Metabolism and Disposition February 2019, 47 (2) 104-113; DOI: https://doi.org/10.1124/dmd.118.080549
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