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Index by author

March 01, 2019; Volume 47,Issue 3

A

  1. Amlal, Hassane

    1. A Recombinant Humanized Anticocaine Monoclonal Antibody Alters the Urinary Clearance of Cocaine and Its Metabolites in Rats
      Jordan A. Marckel, Hanna N. Wetzel, Sihame Amlal, Hassane Amlal and Andrew B. Norman
      Drug Metabolism and Disposition March 2019, 47 (3) 184-188; DOI: https://doi.org/10.1124/dmd.118.083857

  2. Amlal, Sihame

    1. A Recombinant Humanized Anticocaine Monoclonal Antibody Alters the Urinary Clearance of Cocaine and Its Metabolites in Rats
      Jordan A. Marckel, Hanna N. Wetzel, Sihame Amlal, Hassane Amlal and Andrew B. Norman
      Drug Metabolism and Disposition March 2019, 47 (3) 184-188; DOI: https://doi.org/10.1124/dmd.118.083857

  3. Ando, Osamu

    1. Pharmacokinetics, Metabolism, and Excretion of [14C]Esaxerenone, a Novel Mineralocorticoid Receptor Blocker in Humans
      Makiko Yamada, Jeanne Mendell, Hideo Takakusa, Takako Shimizu and Osamu Ando
      Drug Metabolism and Disposition March 2019, 47 (3) 340-349; DOI: https://doi.org/10.1124/dmd.118.084897

  4. Annaert, Pieter P. J.

    1. Ontogeny of ADME Processes during Postnatal Development in Man and Preclinical Species: A Comprehensive Review
      Luc M. De Schaepdrijver, Pieter P. J. Annaert and Connie L. Chen
      Drug Metabolism and Disposition March 2019, 47 (3) 295; DOI: https://doi.org/10.1124/dmd.118.084350

  5. Anoshchenko, Olena

    1. Hepatic Enzymes Relevant to the Disposition of (−)-∆9-Tetrahydrocannabinol (THC) and Its Psychoactive Metabolite, 11-OH-THC
      Gabriela I. Patilea-Vrana, Olena Anoshchenko and Jashvant D. Unadkat
      Drug Metabolism and Disposition March 2019, 47 (3) 249-256; DOI: https://doi.org/10.1124/dmd.118.085548

  6. Aradi, Allister E.

    1. Kinetics of Cyclophosphamide Metabolism in Humans, Dogs, Cats, and Mice and Relationship to Cytotoxic Activity and Pharmacokinetics
      Dominique A. Ramirez, Keagan P. Collins, Allister E. Aradi, Katherine A. Conger and Daniel L. Gustafson
      Drug Metabolism and Disposition March 2019, 47 (3) 257-268; DOI: https://doi.org/10.1124/dmd.118.083766

B

  1. Bao, Jingqi

    1. Hepatic Organic Anion Transporting Polypeptide–Mediated Clearance in the Beagle Dog: Assessing In Vitro–In Vivo Relationships and Applying Cross-Species Empirical Scaling Factors to Improve Prediction of Human Clearance
      Norikazu Matsunaga, Ayşe Ufuk, Bridget L. Morse, David W. Bedwell, Jingqi Bao, Michael A. Mohutsky, Kathleen M. Hillgren, Stephen D. Hall, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition March 2019, 47 (3) 215-226; DOI: https://doi.org/10.1124/dmd.118.084194

  2. Bateman, Thomas

    1. Characterization of Anacetrapib Distribution into the Lipid Droplet of Adipose Tissue in Mice and Human Cultured Adipocytes
      Douglas G. Johns, Lauretta LeVoci, Mihajlo Krsmanovic, Min Lu, Georgy Hartmann, Suoyu Xu, Sheng-Ping Wang, Ying Chen, Thomas Bateman and Robert O. Blaustein
      Drug Metabolism and Disposition March 2019, 47 (3) 227-233; DOI: https://doi.org/10.1124/dmd.118.084525

  3. Bedwell, David W.

    1. Hepatic Organic Anion Transporting Polypeptide–Mediated Clearance in the Beagle Dog: Assessing In Vitro–In Vivo Relationships and Applying Cross-Species Empirical Scaling Factors to Improve Prediction of Human Clearance
      Norikazu Matsunaga, Ayşe Ufuk, Bridget L. Morse, David W. Bedwell, Jingqi Bao, Michael A. Mohutsky, Kathleen M. Hillgren, Stephen D. Hall, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition March 2019, 47 (3) 215-226; DOI: https://doi.org/10.1124/dmd.118.084194

  4. Blaustein, Robert O.

    1. Characterization of Anacetrapib Distribution into the Lipid Droplet of Adipose Tissue in Mice and Human Cultured Adipocytes
      Douglas G. Johns, Lauretta LeVoci, Mihajlo Krsmanovic, Min Lu, Georgy Hartmann, Suoyu Xu, Sheng-Ping Wang, Ying Chen, Thomas Bateman and Robert O. Blaustein
      Drug Metabolism and Disposition March 2019, 47 (3) 227-233; DOI: https://doi.org/10.1124/dmd.118.084525

  5. Brouwer, Kim L. R.

    1. Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Jian Zhang, Ling-Zhi Gao, Yu-Jie Chen, Ping-Ping Zhu, Shan-Shan Yin, Ming-Ming Su, Yan Ni, Jia Miao, Wen-Lin Wu, Hong Chen, Kim L. R. Brouwer, Chang-Xiao Liu, Liang Xu, Wei Jia and Ke Lan
      Drug Metabolism and Disposition March 2019, 47 (3) 283-294; DOI: https://doi.org/10.1124/dmd.118.085670

  6. Bruckner, James V.

    1. Age Dependency of Blood-Brain Barrier Penetration by cis- and trans-Permethrin in the Rat
      Tanzir B. Mortuza, Gaylen L. Edwards, Catherine A. White, Vandan Patel, Brian S. Cummings and James V. Bruckner
      Drug Metabolism and Disposition March 2019, 47 (3) 234-237; DOI: https://doi.org/10.1124/dmd.118.084822

  7. Butcher, Neville J.

    1. The MBNL/CELF Splicing Factors Regulate Cytosolic Sulfotransferase 4A1 Protein Expression during Cell Differentiation
      The MBNL/CELF Splicing Factors Regulate Cytosolic Sulfotransferase 4A1 Protein Expression during Cell Differentiation
      Misgana Idris, Neville J. Butcher and Rodney F. Minchin
      Drug Metabolism and Disposition March 2019, 47 (3) 314-319; DOI: https://doi.org/10.1124/dmd.118.085290

C

  1. Chau, Nuy

    1. Drug and Chemical Glucosidation by Control Supersomes and Membranes from Spodoptera frugiperda (Sf) 9 Cells: Implications for the Apparent Glucuronidation of Xenobiotics by UDP-glucuronosyltransferase 1A5
      Nuy Chau, Leyla Kaya, Benjamin C. Lewis, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition March 2019, 47 (3) 271-278; DOI: https://doi.org/10.1124/dmd.118.084947

  2. Chen, Connie L.

    1. Ontogeny of ADME Processes during Postnatal Development in Man and Preclinical Species: A Comprehensive Review
      Luc M. De Schaepdrijver, Pieter P. J. Annaert and Connie L. Chen
      Drug Metabolism and Disposition March 2019, 47 (3) 295; DOI: https://doi.org/10.1124/dmd.118.084350

  3. Chen, Hong

    1. Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Jian Zhang, Ling-Zhi Gao, Yu-Jie Chen, Ping-Ping Zhu, Shan-Shan Yin, Ming-Ming Su, Yan Ni, Jia Miao, Wen-Lin Wu, Hong Chen, Kim L. R. Brouwer, Chang-Xiao Liu, Liang Xu, Wei Jia and Ke Lan
      Drug Metabolism and Disposition March 2019, 47 (3) 283-294; DOI: https://doi.org/10.1124/dmd.118.085670

  4. Chen, Xiaoyan

    1. Hydrolytic Metabolism of Cyanopyrrolidine DPP-4 Inhibitors Mediated by Dipeptidyl Peptidases
      Fandi Kong, Xiaoyan Pang, Jihui Zhao, Pan Deng, Mingyue Zheng, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition March 2019, 47 (3) 238-248; DOI: https://doi.org/10.1124/dmd.118.084640

  5. Chen, Ying

    1. Characterization of Anacetrapib Distribution into the Lipid Droplet of Adipose Tissue in Mice and Human Cultured Adipocytes
      Douglas G. Johns, Lauretta LeVoci, Mihajlo Krsmanovic, Min Lu, Georgy Hartmann, Suoyu Xu, Sheng-Ping Wang, Ying Chen, Thomas Bateman and Robert O. Blaustein
      Drug Metabolism and Disposition March 2019, 47 (3) 227-233; DOI: https://doi.org/10.1124/dmd.118.084525

  6. Chen, Yu-Jie

    1. Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Jian Zhang, Ling-Zhi Gao, Yu-Jie Chen, Ping-Ping Zhu, Shan-Shan Yin, Ming-Ming Su, Yan Ni, Jia Miao, Wen-Lin Wu, Hong Chen, Kim L. R. Brouwer, Chang-Xiao Liu, Liang Xu, Wei Jia and Ke Lan
      Drug Metabolism and Disposition March 2019, 47 (3) 283-294; DOI: https://doi.org/10.1124/dmd.118.085670

  7. Collins, Keagan P.

    1. Kinetics of Cyclophosphamide Metabolism in Humans, Dogs, Cats, and Mice and Relationship to Cytotoxic Activity and Pharmacokinetics
      Dominique A. Ramirez, Keagan P. Collins, Allister E. Aradi, Katherine A. Conger and Daniel L. Gustafson
      Drug Metabolism and Disposition March 2019, 47 (3) 257-268; DOI: https://doi.org/10.1124/dmd.118.083766

  8. Conger, Katherine A.

    1. Kinetics of Cyclophosphamide Metabolism in Humans, Dogs, Cats, and Mice and Relationship to Cytotoxic Activity and Pharmacokinetics
      Dominique A. Ramirez, Keagan P. Collins, Allister E. Aradi, Katherine A. Conger and Daniel L. Gustafson
      Drug Metabolism and Disposition March 2019, 47 (3) 257-268; DOI: https://doi.org/10.1124/dmd.118.083766

  9. Crnkovic, Camila Manoel

    1. Commensal Gut Bacteria Convert the Immunosuppressant Tacrolimus to Less Potent Metabolites
      Yukuang Guo, Camila Manoel Crnkovic, Kyoung-Jae Won, Xiaotong Yang, John Richard Lee, Jimmy Orjala, Hyunwoo Lee and Hyunyoung Jeong
      Drug Metabolism and Disposition March 2019, 47 (3) 194-202; DOI: https://doi.org/10.1124/dmd.118.084772

  10. Crosby, Michael

    1. Suppression of Hepatic CYP3A4 Expression and Activity by 3-Methylcholanthrene in Humanized PXR-CAR-CYP3A4/3A7 Mice
      Michael Crosby and David S. Riddick
      Drug Metabolism and Disposition March 2019, 47 (3) 279-282; DOI: https://doi.org/10.1124/dmd.118.084509

  11. Cui, Julia Yue

    1. Regulation of Hepatic Long Noncoding RNAs by Pregnane X Receptor and Constitutive Androstane Receptor Agonists in Mouse Liver
      Joseph L. Dempsey and Julia Yue Cui
      Drug Metabolism and Disposition March 2019, 47 (3) 329-339; DOI: https://doi.org/10.1124/dmd.118.085142

  12. Cummings, Brian S.

    1. Age Dependency of Blood-Brain Barrier Penetration by cis- and trans-Permethrin in the Rat
      Tanzir B. Mortuza, Gaylen L. Edwards, Catherine A. White, Vandan Patel, Brian S. Cummings and James V. Bruckner
      Drug Metabolism and Disposition March 2019, 47 (3) 234-237; DOI: https://doi.org/10.1124/dmd.118.084822

D

  1. Dempsey, Joseph L.

    1. Regulation of Hepatic Long Noncoding RNAs by Pregnane X Receptor and Constitutive Androstane Receptor Agonists in Mouse Liver
      Joseph L. Dempsey and Julia Yue Cui
      Drug Metabolism and Disposition March 2019, 47 (3) 329-339; DOI: https://doi.org/10.1124/dmd.118.085142

  2. Deng, Pan

    1. Hydrolytic Metabolism of Cyanopyrrolidine DPP-4 Inhibitors Mediated by Dipeptidyl Peptidases
      Fandi Kong, Xiaoyan Pang, Jihui Zhao, Pan Deng, Mingyue Zheng, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition March 2019, 47 (3) 238-248; DOI: https://doi.org/10.1124/dmd.118.084640

  3. De Schaepdrijver, Luc M.

    1. Ontogeny of ADME Processes during Postnatal Development in Man and Preclinical Species: A Comprehensive Review
      Luc M. De Schaepdrijver, Pieter P. J. Annaert and Connie L. Chen
      Drug Metabolism and Disposition March 2019, 47 (3) 295; DOI: https://doi.org/10.1124/dmd.118.084350

E

  1. Edwards, Gaylen L.

    1. Age Dependency of Blood-Brain Barrier Penetration by cis- and trans-Permethrin in the Rat
      Tanzir B. Mortuza, Gaylen L. Edwards, Catherine A. White, Vandan Patel, Brian S. Cummings and James V. Bruckner
      Drug Metabolism and Disposition March 2019, 47 (3) 234-237; DOI: https://doi.org/10.1124/dmd.118.084822

F

  1. Fisher, Jeffrey

    1. Open Access
      Physiology of the Neonatal Gastrointestinal System Relevant to the Disposition of Orally Administered Medications
      April Neal-Kluever, Jeffrey Fisher, Lawrence Grylack, Satoko Kakiuchi-Kiyota and Wendy Halpern
      Drug Metabolism and Disposition March 2019, 47 (3) 296-313; DOI: https://doi.org/10.1124/dmd.118.084418

  2. Fredenhagen, Andreas

    1. Gas-Phase Rearrangement of the <em>O</em>-Glucuronide of Vildagliptin Forms Product-Ion Fragments Suggesting Wrongly an <em>N</em>-Glucuronide
      Gas-Phase Rearrangement of the O-Glucuronide of Vildagliptin Forms Product-Ion Fragments Suggesting Wrongly an N-Glucuronide
      Andreas Fredenhagen, Jürgen Kühnöl, Matthias Kittelmann and Lukas Oberer
      Drug Metabolism and Disposition March 2019, 47 (3) 189-193; DOI: https://doi.org/10.1124/dmd.118.085597

G

  1. Galetin, Aleksandra

    1. Hepatic Organic Anion Transporting Polypeptide–Mediated Clearance in the Beagle Dog: Assessing In Vitro–In Vivo Relationships and Applying Cross-Species Empirical Scaling Factors to Improve Prediction of Human Clearance
      Norikazu Matsunaga, Ayşe Ufuk, Bridget L. Morse, David W. Bedwell, Jingqi Bao, Michael A. Mohutsky, Kathleen M. Hillgren, Stephen D. Hall, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition March 2019, 47 (3) 215-226; DOI: https://doi.org/10.1124/dmd.118.084194

  2. Gao, Ling-Zhi

    1. Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Jian Zhang, Ling-Zhi Gao, Yu-Jie Chen, Ping-Ping Zhu, Shan-Shan Yin, Ming-Ming Su, Yan Ni, Jia Miao, Wen-Lin Wu, Hong Chen, Kim L. R. Brouwer, Chang-Xiao Liu, Liang Xu, Wei Jia and Ke Lan
      Drug Metabolism and Disposition March 2019, 47 (3) 283-294; DOI: https://doi.org/10.1124/dmd.118.085670

  3. Grylack, Lawrence

    1. Open Access
      Physiology of the Neonatal Gastrointestinal System Relevant to the Disposition of Orally Administered Medications
      April Neal-Kluever, Jeffrey Fisher, Lawrence Grylack, Satoko Kakiuchi-Kiyota and Wendy Halpern
      Drug Metabolism and Disposition March 2019, 47 (3) 296-313; DOI: https://doi.org/10.1124/dmd.118.084418

  4. Guo, Yukuang

    1. Commensal Gut Bacteria Convert the Immunosuppressant Tacrolimus to Less Potent Metabolites
      Yukuang Guo, Camila Manoel Crnkovic, Kyoung-Jae Won, Xiaotong Yang, John Richard Lee, Jimmy Orjala, Hyunwoo Lee and Hyunyoung Jeong
      Drug Metabolism and Disposition March 2019, 47 (3) 194-202; DOI: https://doi.org/10.1124/dmd.118.084772

  5. Gustafson, Daniel L.

    1. Kinetics of Cyclophosphamide Metabolism in Humans, Dogs, Cats, and Mice and Relationship to Cytotoxic Activity and Pharmacokinetics
      Dominique A. Ramirez, Keagan P. Collins, Allister E. Aradi, Katherine A. Conger and Daniel L. Gustafson
      Drug Metabolism and Disposition March 2019, 47 (3) 257-268; DOI: https://doi.org/10.1124/dmd.118.083766

H

  1. Hall, Stephen D.

    1. Hepatic Organic Anion Transporting Polypeptide–Mediated Clearance in the Beagle Dog: Assessing In Vitro–In Vivo Relationships and Applying Cross-Species Empirical Scaling Factors to Improve Prediction of Human Clearance
      Norikazu Matsunaga, Ayşe Ufuk, Bridget L. Morse, David W. Bedwell, Jingqi Bao, Michael A. Mohutsky, Kathleen M. Hillgren, Stephen D. Hall, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition March 2019, 47 (3) 215-226; DOI: https://doi.org/10.1124/dmd.118.084194

  2. Hallifax, D.

    1. Use of Segregated Hepatocyte Scaling Factors and Cross-Species Relationships to Resolve Clearance Dependence in the Prediction of Human Hepatic Clearance
      D. Hallifax and J.B. Houston
      Drug Metabolism and Disposition March 2019, 47 (3) 320-327; DOI: https://doi.org/10.1124/dmd.118.085191

  3. Halpern, Wendy

    1. Open Access
      Physiology of the Neonatal Gastrointestinal System Relevant to the Disposition of Orally Administered Medications
      April Neal-Kluever, Jeffrey Fisher, Lawrence Grylack, Satoko Kakiuchi-Kiyota and Wendy Halpern
      Drug Metabolism and Disposition March 2019, 47 (3) 296-313; DOI: https://doi.org/10.1124/dmd.118.084418

  4. Hartmann, Georgy

    1. Characterization of Anacetrapib Distribution into the Lipid Droplet of Adipose Tissue in Mice and Human Cultured Adipocytes
      Douglas G. Johns, Lauretta LeVoci, Mihajlo Krsmanovic, Min Lu, Georgy Hartmann, Suoyu Xu, Sheng-Ping Wang, Ying Chen, Thomas Bateman and Robert O. Blaustein
      Drug Metabolism and Disposition March 2019, 47 (3) 227-233; DOI: https://doi.org/10.1124/dmd.118.084525

  5. Hillgren, Kathleen M.

    1. Hepatic Organic Anion Transporting Polypeptide–Mediated Clearance in the Beagle Dog: Assessing In Vitro–In Vivo Relationships and Applying Cross-Species Empirical Scaling Factors to Improve Prediction of Human Clearance
      Norikazu Matsunaga, Ayşe Ufuk, Bridget L. Morse, David W. Bedwell, Jingqi Bao, Michael A. Mohutsky, Kathleen M. Hillgren, Stephen D. Hall, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition March 2019, 47 (3) 215-226; DOI: https://doi.org/10.1124/dmd.118.084194

  6. Houston, J.B.

    1. Use of Segregated Hepatocyte Scaling Factors and Cross-Species Relationships to Resolve Clearance Dependence in the Prediction of Human Hepatic Clearance
      D. Hallifax and J.B. Houston
      Drug Metabolism and Disposition March 2019, 47 (3) 320-327; DOI: https://doi.org/10.1124/dmd.118.085191

  7. Houston, J. Brian

    1. Hepatic Organic Anion Transporting Polypeptide–Mediated Clearance in the Beagle Dog: Assessing In Vitro–In Vivo Relationships and Applying Cross-Species Empirical Scaling Factors to Improve Prediction of Human Clearance
      Norikazu Matsunaga, Ayşe Ufuk, Bridget L. Morse, David W. Bedwell, Jingqi Bao, Michael A. Mohutsky, Kathleen M. Hillgren, Stephen D. Hall, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition March 2019, 47 (3) 215-226; DOI: https://doi.org/10.1124/dmd.118.084194

  8. Hu, Ming

    1. Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide
      Yuhuan Li, Wenjie Song, Xiaojun Ou, Guangkuo Luo, Yushan Xie, Rongjin Sun, Ying Wang, Xiaoxiao Qi, Ming Hu, Zhongqiu Liu and Lijun Zhu
      Drug Metabolism and Disposition March 2019, 47 (3) 203-214; DOI: https://doi.org/10.1124/dmd.118.083493

  9. Hu, Yongjun

    1. In Silico Prediction of the Absorption and Disposition of Cefadroxil in Humans using an Intestinal Permeability Method Scaled from Humanized PepT1 Mice
      Yongjun Hu and David E. Smith
      Drug Metabolism and Disposition March 2019, 47 (3) 173-183; DOI: https://doi.org/10.1124/dmd.118.084236

I

  1. Idris, Misgana

    1. The MBNL/CELF Splicing Factors Regulate Cytosolic Sulfotransferase 4A1 Protein Expression during Cell Differentiation
      The MBNL/CELF Splicing Factors Regulate Cytosolic Sulfotransferase 4A1 Protein Expression during Cell Differentiation
      Misgana Idris, Neville J. Butcher and Rodney F. Minchin
      Drug Metabolism and Disposition March 2019, 47 (3) 314-319; DOI: https://doi.org/10.1124/dmd.118.085290

J

  1. Jeong, Hyunyoung

    1. Commensal Gut Bacteria Convert the Immunosuppressant Tacrolimus to Less Potent Metabolites
      Yukuang Guo, Camila Manoel Crnkovic, Kyoung-Jae Won, Xiaotong Yang, John Richard Lee, Jimmy Orjala, Hyunwoo Lee and Hyunyoung Jeong
      Drug Metabolism and Disposition March 2019, 47 (3) 194-202; DOI: https://doi.org/10.1124/dmd.118.084772

  2. Jia, Wei

    1. Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Jian Zhang, Ling-Zhi Gao, Yu-Jie Chen, Ping-Ping Zhu, Shan-Shan Yin, Ming-Ming Su, Yan Ni, Jia Miao, Wen-Lin Wu, Hong Chen, Kim L. R. Brouwer, Chang-Xiao Liu, Liang Xu, Wei Jia and Ke Lan
      Drug Metabolism and Disposition March 2019, 47 (3) 283-294; DOI: https://doi.org/10.1124/dmd.118.085670

  3. Johns, Douglas G.

    1. Characterization of Anacetrapib Distribution into the Lipid Droplet of Adipose Tissue in Mice and Human Cultured Adipocytes
      Douglas G. Johns, Lauretta LeVoci, Mihajlo Krsmanovic, Min Lu, Georgy Hartmann, Suoyu Xu, Sheng-Ping Wang, Ying Chen, Thomas Bateman and Robert O. Blaustein
      Drug Metabolism and Disposition March 2019, 47 (3) 227-233; DOI: https://doi.org/10.1124/dmd.118.084525

K

  1. Kakiuchi-Kiyota, Satoko

    1. Open Access
      Physiology of the Neonatal Gastrointestinal System Relevant to the Disposition of Orally Administered Medications
      April Neal-Kluever, Jeffrey Fisher, Lawrence Grylack, Satoko Kakiuchi-Kiyota and Wendy Halpern
      Drug Metabolism and Disposition March 2019, 47 (3) 296-313; DOI: https://doi.org/10.1124/dmd.118.084418

  2. Kaya, Leyla

    1. Drug and Chemical Glucosidation by Control Supersomes and Membranes from Spodoptera frugiperda (Sf) 9 Cells: Implications for the Apparent Glucuronidation of Xenobiotics by UDP-glucuronosyltransferase 1A5
      Nuy Chau, Leyla Kaya, Benjamin C. Lewis, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition March 2019, 47 (3) 271-278; DOI: https://doi.org/10.1124/dmd.118.084947

  3. Kittelmann, Matthias

    1. Gas-Phase Rearrangement of the <em>O</em>-Glucuronide of Vildagliptin Forms Product-Ion Fragments Suggesting Wrongly an <em>N</em>-Glucuronide
      Gas-Phase Rearrangement of the O-Glucuronide of Vildagliptin Forms Product-Ion Fragments Suggesting Wrongly an N-Glucuronide
      Andreas Fredenhagen, Jürgen Kühnöl, Matthias Kittelmann and Lukas Oberer
      Drug Metabolism and Disposition March 2019, 47 (3) 189-193; DOI: https://doi.org/10.1124/dmd.118.085597

  4. Kong, Fandi

    1. Hydrolytic Metabolism of Cyanopyrrolidine DPP-4 Inhibitors Mediated by Dipeptidyl Peptidases
      Fandi Kong, Xiaoyan Pang, Jihui Zhao, Pan Deng, Mingyue Zheng, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition March 2019, 47 (3) 238-248; DOI: https://doi.org/10.1124/dmd.118.084640

  5. Krsmanovic, Mihajlo

    1. Characterization of Anacetrapib Distribution into the Lipid Droplet of Adipose Tissue in Mice and Human Cultured Adipocytes
      Douglas G. Johns, Lauretta LeVoci, Mihajlo Krsmanovic, Min Lu, Georgy Hartmann, Suoyu Xu, Sheng-Ping Wang, Ying Chen, Thomas Bateman and Robert O. Blaustein
      Drug Metabolism and Disposition March 2019, 47 (3) 227-233; DOI: https://doi.org/10.1124/dmd.118.084525

  6. Kühnöl, Jürgen

    1. Gas-Phase Rearrangement of the <em>O</em>-Glucuronide of Vildagliptin Forms Product-Ion Fragments Suggesting Wrongly an <em>N</em>-Glucuronide
      Gas-Phase Rearrangement of the O-Glucuronide of Vildagliptin Forms Product-Ion Fragments Suggesting Wrongly an N-Glucuronide
      Andreas Fredenhagen, Jürgen Kühnöl, Matthias Kittelmann and Lukas Oberer
      Drug Metabolism and Disposition March 2019, 47 (3) 189-193; DOI: https://doi.org/10.1124/dmd.118.085597

L

  1. Lan, Ke

    1. Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Jian Zhang, Ling-Zhi Gao, Yu-Jie Chen, Ping-Ping Zhu, Shan-Shan Yin, Ming-Ming Su, Yan Ni, Jia Miao, Wen-Lin Wu, Hong Chen, Kim L. R. Brouwer, Chang-Xiao Liu, Liang Xu, Wei Jia and Ke Lan
      Drug Metabolism and Disposition March 2019, 47 (3) 283-294; DOI: https://doi.org/10.1124/dmd.118.085670

  2. Lee, Hyunwoo

    1. Commensal Gut Bacteria Convert the Immunosuppressant Tacrolimus to Less Potent Metabolites
      Yukuang Guo, Camila Manoel Crnkovic, Kyoung-Jae Won, Xiaotong Yang, John Richard Lee, Jimmy Orjala, Hyunwoo Lee and Hyunyoung Jeong
      Drug Metabolism and Disposition March 2019, 47 (3) 194-202; DOI: https://doi.org/10.1124/dmd.118.084772

  3. Lee, John Richard

    1. Commensal Gut Bacteria Convert the Immunosuppressant Tacrolimus to Less Potent Metabolites
      Yukuang Guo, Camila Manoel Crnkovic, Kyoung-Jae Won, Xiaotong Yang, John Richard Lee, Jimmy Orjala, Hyunwoo Lee and Hyunyoung Jeong
      Drug Metabolism and Disposition March 2019, 47 (3) 194-202; DOI: https://doi.org/10.1124/dmd.118.084772

  4. LeVoci, Lauretta

    1. Characterization of Anacetrapib Distribution into the Lipid Droplet of Adipose Tissue in Mice and Human Cultured Adipocytes
      Douglas G. Johns, Lauretta LeVoci, Mihajlo Krsmanovic, Min Lu, Georgy Hartmann, Suoyu Xu, Sheng-Ping Wang, Ying Chen, Thomas Bateman and Robert O. Blaustein
      Drug Metabolism and Disposition March 2019, 47 (3) 227-233; DOI: https://doi.org/10.1124/dmd.118.084525

  5. Lewis, Benjamin C.

    1. Drug and Chemical Glucosidation by Control Supersomes and Membranes from Spodoptera frugiperda (Sf) 9 Cells: Implications for the Apparent Glucuronidation of Xenobiotics by UDP-glucuronosyltransferase 1A5
      Nuy Chau, Leyla Kaya, Benjamin C. Lewis, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition March 2019, 47 (3) 271-278; DOI: https://doi.org/10.1124/dmd.118.084947

  6. Li, Yuhuan

    1. Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide
      Yuhuan Li, Wenjie Song, Xiaojun Ou, Guangkuo Luo, Yushan Xie, Rongjin Sun, Ying Wang, Xiaoxiao Qi, Ming Hu, Zhongqiu Liu and Lijun Zhu
      Drug Metabolism and Disposition March 2019, 47 (3) 203-214; DOI: https://doi.org/10.1124/dmd.118.083493

  7. Liu, Chang-Xiao

    1. Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Jian Zhang, Ling-Zhi Gao, Yu-Jie Chen, Ping-Ping Zhu, Shan-Shan Yin, Ming-Ming Su, Yan Ni, Jia Miao, Wen-Lin Wu, Hong Chen, Kim L. R. Brouwer, Chang-Xiao Liu, Liang Xu, Wei Jia and Ke Lan
      Drug Metabolism and Disposition March 2019, 47 (3) 283-294; DOI: https://doi.org/10.1124/dmd.118.085670

  8. Liu, Zhongqiu

    1. Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide
      Yuhuan Li, Wenjie Song, Xiaojun Ou, Guangkuo Luo, Yushan Xie, Rongjin Sun, Ying Wang, Xiaoxiao Qi, Ming Hu, Zhongqiu Liu and Lijun Zhu
      Drug Metabolism and Disposition March 2019, 47 (3) 203-214; DOI: https://doi.org/10.1124/dmd.118.083493

  9. Lu, Min

    1. Characterization of Anacetrapib Distribution into the Lipid Droplet of Adipose Tissue in Mice and Human Cultured Adipocytes
      Douglas G. Johns, Lauretta LeVoci, Mihajlo Krsmanovic, Min Lu, Georgy Hartmann, Suoyu Xu, Sheng-Ping Wang, Ying Chen, Thomas Bateman and Robert O. Blaustein
      Drug Metabolism and Disposition March 2019, 47 (3) 227-233; DOI: https://doi.org/10.1124/dmd.118.084525

  10. Luo, Guangkuo

    1. Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide
      Yuhuan Li, Wenjie Song, Xiaojun Ou, Guangkuo Luo, Yushan Xie, Rongjin Sun, Ying Wang, Xiaoxiao Qi, Ming Hu, Zhongqiu Liu and Lijun Zhu
      Drug Metabolism and Disposition March 2019, 47 (3) 203-214; DOI: https://doi.org/10.1124/dmd.118.083493

M

  1. Mackenzie, Peter I.

    1. Drug and Chemical Glucosidation by Control Supersomes and Membranes from Spodoptera frugiperda (Sf) 9 Cells: Implications for the Apparent Glucuronidation of Xenobiotics by UDP-glucuronosyltransferase 1A5
      Nuy Chau, Leyla Kaya, Benjamin C. Lewis, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition March 2019, 47 (3) 271-278; DOI: https://doi.org/10.1124/dmd.118.084947

  2. Marckel, Jordan A.

    1. A Recombinant Humanized Anticocaine Monoclonal Antibody Alters the Urinary Clearance of Cocaine and Its Metabolites in Rats
      Jordan A. Marckel, Hanna N. Wetzel, Sihame Amlal, Hassane Amlal and Andrew B. Norman
      Drug Metabolism and Disposition March 2019, 47 (3) 184-188; DOI: https://doi.org/10.1124/dmd.118.083857

  3. Matsunaga, Norikazu

    1. Hepatic Organic Anion Transporting Polypeptide–Mediated Clearance in the Beagle Dog: Assessing In Vitro–In Vivo Relationships and Applying Cross-Species Empirical Scaling Factors to Improve Prediction of Human Clearance
      Norikazu Matsunaga, Ayşe Ufuk, Bridget L. Morse, David W. Bedwell, Jingqi Bao, Michael A. Mohutsky, Kathleen M. Hillgren, Stephen D. Hall, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition March 2019, 47 (3) 215-226; DOI: https://doi.org/10.1124/dmd.118.084194

  4. Mendell, Jeanne

    1. Pharmacokinetics, Metabolism, and Excretion of [14C]Esaxerenone, a Novel Mineralocorticoid Receptor Blocker in Humans
      Makiko Yamada, Jeanne Mendell, Hideo Takakusa, Takako Shimizu and Osamu Ando
      Drug Metabolism and Disposition March 2019, 47 (3) 340-349; DOI: https://doi.org/10.1124/dmd.118.084897

  5. Miao, Jia

    1. Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Jian Zhang, Ling-Zhi Gao, Yu-Jie Chen, Ping-Ping Zhu, Shan-Shan Yin, Ming-Ming Su, Yan Ni, Jia Miao, Wen-Lin Wu, Hong Chen, Kim L. R. Brouwer, Chang-Xiao Liu, Liang Xu, Wei Jia and Ke Lan
      Drug Metabolism and Disposition March 2019, 47 (3) 283-294; DOI: https://doi.org/10.1124/dmd.118.085670

  6. Minchin, Rodney F.

    1. The MBNL/CELF Splicing Factors Regulate Cytosolic Sulfotransferase 4A1 Protein Expression during Cell Differentiation
      The MBNL/CELF Splicing Factors Regulate Cytosolic Sulfotransferase 4A1 Protein Expression during Cell Differentiation
      Misgana Idris, Neville J. Butcher and Rodney F. Minchin
      Drug Metabolism and Disposition March 2019, 47 (3) 314-319; DOI: https://doi.org/10.1124/dmd.118.085290

  7. Miners, John O.

    1. Drug and Chemical Glucosidation by Control Supersomes and Membranes from Spodoptera frugiperda (Sf) 9 Cells: Implications for the Apparent Glucuronidation of Xenobiotics by UDP-glucuronosyltransferase 1A5
      Nuy Chau, Leyla Kaya, Benjamin C. Lewis, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition March 2019, 47 (3) 271-278; DOI: https://doi.org/10.1124/dmd.118.084947

  8. Mohutsky, Michael A.

    1. Hepatic Organic Anion Transporting Polypeptide–Mediated Clearance in the Beagle Dog: Assessing In Vitro–In Vivo Relationships and Applying Cross-Species Empirical Scaling Factors to Improve Prediction of Human Clearance
      Norikazu Matsunaga, Ayşe Ufuk, Bridget L. Morse, David W. Bedwell, Jingqi Bao, Michael A. Mohutsky, Kathleen M. Hillgren, Stephen D. Hall, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition March 2019, 47 (3) 215-226; DOI: https://doi.org/10.1124/dmd.118.084194

  9. Morse, Bridget L.

    1. Hepatic Organic Anion Transporting Polypeptide–Mediated Clearance in the Beagle Dog: Assessing In Vitro–In Vivo Relationships and Applying Cross-Species Empirical Scaling Factors to Improve Prediction of Human Clearance
      Norikazu Matsunaga, Ayşe Ufuk, Bridget L. Morse, David W. Bedwell, Jingqi Bao, Michael A. Mohutsky, Kathleen M. Hillgren, Stephen D. Hall, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition March 2019, 47 (3) 215-226; DOI: https://doi.org/10.1124/dmd.118.084194

  10. Mortuza, Tanzir B.

    1. Age Dependency of Blood-Brain Barrier Penetration by cis- and trans-Permethrin in the Rat
      Tanzir B. Mortuza, Gaylen L. Edwards, Catherine A. White, Vandan Patel, Brian S. Cummings and James V. Bruckner
      Drug Metabolism and Disposition March 2019, 47 (3) 234-237; DOI: https://doi.org/10.1124/dmd.118.084822

N

  1. Neal-Kluever, April

    1. Open Access
      Physiology of the Neonatal Gastrointestinal System Relevant to the Disposition of Orally Administered Medications
      April Neal-Kluever, Jeffrey Fisher, Lawrence Grylack, Satoko Kakiuchi-Kiyota and Wendy Halpern
      Drug Metabolism and Disposition March 2019, 47 (3) 296-313; DOI: https://doi.org/10.1124/dmd.118.084418

  2. Ni, Yan

    1. Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Jian Zhang, Ling-Zhi Gao, Yu-Jie Chen, Ping-Ping Zhu, Shan-Shan Yin, Ming-Ming Su, Yan Ni, Jia Miao, Wen-Lin Wu, Hong Chen, Kim L. R. Brouwer, Chang-Xiao Liu, Liang Xu, Wei Jia and Ke Lan
      Drug Metabolism and Disposition March 2019, 47 (3) 283-294; DOI: https://doi.org/10.1124/dmd.118.085670

  3. Norman, Andrew B.

    1. A Recombinant Humanized Anticocaine Monoclonal Antibody Alters the Urinary Clearance of Cocaine and Its Metabolites in Rats
      Jordan A. Marckel, Hanna N. Wetzel, Sihame Amlal, Hassane Amlal and Andrew B. Norman
      Drug Metabolism and Disposition March 2019, 47 (3) 184-188; DOI: https://doi.org/10.1124/dmd.118.083857

O

  1. Oberer, Lukas

    1. Gas-Phase Rearrangement of the <em>O</em>-Glucuronide of Vildagliptin Forms Product-Ion Fragments Suggesting Wrongly an <em>N</em>-Glucuronide
      Gas-Phase Rearrangement of the O-Glucuronide of Vildagliptin Forms Product-Ion Fragments Suggesting Wrongly an N-Glucuronide
      Andreas Fredenhagen, Jürgen Kühnöl, Matthias Kittelmann and Lukas Oberer
      Drug Metabolism and Disposition March 2019, 47 (3) 189-193; DOI: https://doi.org/10.1124/dmd.118.085597

  2. Orjala, Jimmy

    1. Commensal Gut Bacteria Convert the Immunosuppressant Tacrolimus to Less Potent Metabolites
      Yukuang Guo, Camila Manoel Crnkovic, Kyoung-Jae Won, Xiaotong Yang, John Richard Lee, Jimmy Orjala, Hyunwoo Lee and Hyunyoung Jeong
      Drug Metabolism and Disposition March 2019, 47 (3) 194-202; DOI: https://doi.org/10.1124/dmd.118.084772

  3. Ou, Xiaojun

    1. Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide
      Yuhuan Li, Wenjie Song, Xiaojun Ou, Guangkuo Luo, Yushan Xie, Rongjin Sun, Ying Wang, Xiaoxiao Qi, Ming Hu, Zhongqiu Liu and Lijun Zhu
      Drug Metabolism and Disposition March 2019, 47 (3) 203-214; DOI: https://doi.org/10.1124/dmd.118.083493

P

  1. Pang, Xiaoyan

    1. Hydrolytic Metabolism of Cyanopyrrolidine DPP-4 Inhibitors Mediated by Dipeptidyl Peptidases
      Fandi Kong, Xiaoyan Pang, Jihui Zhao, Pan Deng, Mingyue Zheng, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition March 2019, 47 (3) 238-248; DOI: https://doi.org/10.1124/dmd.118.084640

  2. Patel, Vandan

    1. Age Dependency of Blood-Brain Barrier Penetration by cis- and trans-Permethrin in the Rat
      Tanzir B. Mortuza, Gaylen L. Edwards, Catherine A. White, Vandan Patel, Brian S. Cummings and James V. Bruckner
      Drug Metabolism and Disposition March 2019, 47 (3) 234-237; DOI: https://doi.org/10.1124/dmd.118.084822

  3. Patilea-Vrana, Gabriela I.

    1. Hepatic Enzymes Relevant to the Disposition of (−)-∆9-Tetrahydrocannabinol (THC) and Its Psychoactive Metabolite, 11-OH-THC
      Gabriela I. Patilea-Vrana, Olena Anoshchenko and Jashvant D. Unadkat
      Drug Metabolism and Disposition March 2019, 47 (3) 249-256; DOI: https://doi.org/10.1124/dmd.118.085548

Q

  1. Qi, Xiaoxiao

    1. Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide
      Yuhuan Li, Wenjie Song, Xiaojun Ou, Guangkuo Luo, Yushan Xie, Rongjin Sun, Ying Wang, Xiaoxiao Qi, Ming Hu, Zhongqiu Liu and Lijun Zhu
      Drug Metabolism and Disposition March 2019, 47 (3) 203-214; DOI: https://doi.org/10.1124/dmd.118.083493

R

  1. Ramirez, Dominique A.

    1. Kinetics of Cyclophosphamide Metabolism in Humans, Dogs, Cats, and Mice and Relationship to Cytotoxic Activity and Pharmacokinetics
      Dominique A. Ramirez, Keagan P. Collins, Allister E. Aradi, Katherine A. Conger and Daniel L. Gustafson
      Drug Metabolism and Disposition March 2019, 47 (3) 257-268; DOI: https://doi.org/10.1124/dmd.118.083766

  2. Riddick, David S.

    1. Suppression of Hepatic CYP3A4 Expression and Activity by 3-Methylcholanthrene in Humanized PXR-CAR-CYP3A4/3A7 Mice
      Michael Crosby and David S. Riddick
      Drug Metabolism and Disposition March 2019, 47 (3) 279-282; DOI: https://doi.org/10.1124/dmd.118.084509

S

  1. Shimizu, Takako

    1. Pharmacokinetics, Metabolism, and Excretion of [14C]Esaxerenone, a Novel Mineralocorticoid Receptor Blocker in Humans
      Makiko Yamada, Jeanne Mendell, Hideo Takakusa, Takako Shimizu and Osamu Ando
      Drug Metabolism and Disposition March 2019, 47 (3) 340-349; DOI: https://doi.org/10.1124/dmd.118.084897

  2. Smith, David E.

    1. In Silico Prediction of the Absorption and Disposition of Cefadroxil in Humans using an Intestinal Permeability Method Scaled from Humanized PepT1 Mice
      Yongjun Hu and David E. Smith
      Drug Metabolism and Disposition March 2019, 47 (3) 173-183; DOI: https://doi.org/10.1124/dmd.118.084236

  3. Song, Wenjie

    1. Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide
      Yuhuan Li, Wenjie Song, Xiaojun Ou, Guangkuo Luo, Yushan Xie, Rongjin Sun, Ying Wang, Xiaoxiao Qi, Ming Hu, Zhongqiu Liu and Lijun Zhu
      Drug Metabolism and Disposition March 2019, 47 (3) 203-214; DOI: https://doi.org/10.1124/dmd.118.083493

  4. Su, Ming-Ming

    1. Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Jian Zhang, Ling-Zhi Gao, Yu-Jie Chen, Ping-Ping Zhu, Shan-Shan Yin, Ming-Ming Su, Yan Ni, Jia Miao, Wen-Lin Wu, Hong Chen, Kim L. R. Brouwer, Chang-Xiao Liu, Liang Xu, Wei Jia and Ke Lan
      Drug Metabolism and Disposition March 2019, 47 (3) 283-294; DOI: https://doi.org/10.1124/dmd.118.085670

  5. Sun, Rongjin

    1. Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide
      Yuhuan Li, Wenjie Song, Xiaojun Ou, Guangkuo Luo, Yushan Xie, Rongjin Sun, Ying Wang, Xiaoxiao Qi, Ming Hu, Zhongqiu Liu and Lijun Zhu
      Drug Metabolism and Disposition March 2019, 47 (3) 203-214; DOI: https://doi.org/10.1124/dmd.118.083493

T

  1. Takakusa, Hideo

    1. Pharmacokinetics, Metabolism, and Excretion of [14C]Esaxerenone, a Novel Mineralocorticoid Receptor Blocker in Humans
      Makiko Yamada, Jeanne Mendell, Hideo Takakusa, Takako Shimizu and Osamu Ando
      Drug Metabolism and Disposition March 2019, 47 (3) 340-349; DOI: https://doi.org/10.1124/dmd.118.084897

U

  1. Ufuk, Ayşe

    1. Hepatic Organic Anion Transporting Polypeptide–Mediated Clearance in the Beagle Dog: Assessing In Vitro–In Vivo Relationships and Applying Cross-Species Empirical Scaling Factors to Improve Prediction of Human Clearance
      Norikazu Matsunaga, Ayşe Ufuk, Bridget L. Morse, David W. Bedwell, Jingqi Bao, Michael A. Mohutsky, Kathleen M. Hillgren, Stephen D. Hall, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition March 2019, 47 (3) 215-226; DOI: https://doi.org/10.1124/dmd.118.084194

  2. Unadkat, Jashvant D.

    1. Hepatic Enzymes Relevant to the Disposition of (−)-∆9-Tetrahydrocannabinol (THC) and Its Psychoactive Metabolite, 11-OH-THC
      Gabriela I. Patilea-Vrana, Olena Anoshchenko and Jashvant D. Unadkat
      Drug Metabolism and Disposition March 2019, 47 (3) 249-256; DOI: https://doi.org/10.1124/dmd.118.085548

W

  1. Wang, Sheng-Ping

    1. Characterization of Anacetrapib Distribution into the Lipid Droplet of Adipose Tissue in Mice and Human Cultured Adipocytes
      Douglas G. Johns, Lauretta LeVoci, Mihajlo Krsmanovic, Min Lu, Georgy Hartmann, Suoyu Xu, Sheng-Ping Wang, Ying Chen, Thomas Bateman and Robert O. Blaustein
      Drug Metabolism and Disposition March 2019, 47 (3) 227-233; DOI: https://doi.org/10.1124/dmd.118.084525

  2. Wang, Ying

    1. Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide
      Yuhuan Li, Wenjie Song, Xiaojun Ou, Guangkuo Luo, Yushan Xie, Rongjin Sun, Ying Wang, Xiaoxiao Qi, Ming Hu, Zhongqiu Liu and Lijun Zhu
      Drug Metabolism and Disposition March 2019, 47 (3) 203-214; DOI: https://doi.org/10.1124/dmd.118.083493

  3. Wetzel, Hanna N.

    1. A Recombinant Humanized Anticocaine Monoclonal Antibody Alters the Urinary Clearance of Cocaine and Its Metabolites in Rats
      Jordan A. Marckel, Hanna N. Wetzel, Sihame Amlal, Hassane Amlal and Andrew B. Norman
      Drug Metabolism and Disposition March 2019, 47 (3) 184-188; DOI: https://doi.org/10.1124/dmd.118.083857

  4. White, Catherine A.

    1. Age Dependency of Blood-Brain Barrier Penetration by cis- and trans-Permethrin in the Rat
      Tanzir B. Mortuza, Gaylen L. Edwards, Catherine A. White, Vandan Patel, Brian S. Cummings and James V. Bruckner
      Drug Metabolism and Disposition March 2019, 47 (3) 234-237; DOI: https://doi.org/10.1124/dmd.118.084822

  5. Won, Kyoung-Jae

    1. Commensal Gut Bacteria Convert the Immunosuppressant Tacrolimus to Less Potent Metabolites
      Yukuang Guo, Camila Manoel Crnkovic, Kyoung-Jae Won, Xiaotong Yang, John Richard Lee, Jimmy Orjala, Hyunwoo Lee and Hyunyoung Jeong
      Drug Metabolism and Disposition March 2019, 47 (3) 194-202; DOI: https://doi.org/10.1124/dmd.118.084772

  6. Wu, Wen-Lin

    1. Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Jian Zhang, Ling-Zhi Gao, Yu-Jie Chen, Ping-Ping Zhu, Shan-Shan Yin, Ming-Ming Su, Yan Ni, Jia Miao, Wen-Lin Wu, Hong Chen, Kim L. R. Brouwer, Chang-Xiao Liu, Liang Xu, Wei Jia and Ke Lan
      Drug Metabolism and Disposition March 2019, 47 (3) 283-294; DOI: https://doi.org/10.1124/dmd.118.085670

X

  1. Xie, Yushan

    1. Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide
      Yuhuan Li, Wenjie Song, Xiaojun Ou, Guangkuo Luo, Yushan Xie, Rongjin Sun, Ying Wang, Xiaoxiao Qi, Ming Hu, Zhongqiu Liu and Lijun Zhu
      Drug Metabolism and Disposition March 2019, 47 (3) 203-214; DOI: https://doi.org/10.1124/dmd.118.083493

  2. Xu, Liang

    1. Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Jian Zhang, Ling-Zhi Gao, Yu-Jie Chen, Ping-Ping Zhu, Shan-Shan Yin, Ming-Ming Su, Yan Ni, Jia Miao, Wen-Lin Wu, Hong Chen, Kim L. R. Brouwer, Chang-Xiao Liu, Liang Xu, Wei Jia and Ke Lan
      Drug Metabolism and Disposition March 2019, 47 (3) 283-294; DOI: https://doi.org/10.1124/dmd.118.085670

  3. Xu, Suoyu

    1. Characterization of Anacetrapib Distribution into the Lipid Droplet of Adipose Tissue in Mice and Human Cultured Adipocytes
      Douglas G. Johns, Lauretta LeVoci, Mihajlo Krsmanovic, Min Lu, Georgy Hartmann, Suoyu Xu, Sheng-Ping Wang, Ying Chen, Thomas Bateman and Robert O. Blaustein
      Drug Metabolism and Disposition March 2019, 47 (3) 227-233; DOI: https://doi.org/10.1124/dmd.118.084525

Y

  1. Yamada, Makiko

    1. Pharmacokinetics, Metabolism, and Excretion of [14C]Esaxerenone, a Novel Mineralocorticoid Receptor Blocker in Humans
      Makiko Yamada, Jeanne Mendell, Hideo Takakusa, Takako Shimizu and Osamu Ando
      Drug Metabolism and Disposition March 2019, 47 (3) 340-349; DOI: https://doi.org/10.1124/dmd.118.084897

  2. Yang, Xiaotong

    1. Commensal Gut Bacteria Convert the Immunosuppressant Tacrolimus to Less Potent Metabolites
      Yukuang Guo, Camila Manoel Crnkovic, Kyoung-Jae Won, Xiaotong Yang, John Richard Lee, Jimmy Orjala, Hyunwoo Lee and Hyunyoung Jeong
      Drug Metabolism and Disposition March 2019, 47 (3) 194-202; DOI: https://doi.org/10.1124/dmd.118.084772

  3. Yin, Shan-Shan

    1. Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Jian Zhang, Ling-Zhi Gao, Yu-Jie Chen, Ping-Ping Zhu, Shan-Shan Yin, Ming-Ming Su, Yan Ni, Jia Miao, Wen-Lin Wu, Hong Chen, Kim L. R. Brouwer, Chang-Xiao Liu, Liang Xu, Wei Jia and Ke Lan
      Drug Metabolism and Disposition March 2019, 47 (3) 283-294; DOI: https://doi.org/10.1124/dmd.118.085670

Z

  1. Zhang, Jian

    1. Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Jian Zhang, Ling-Zhi Gao, Yu-Jie Chen, Ping-Ping Zhu, Shan-Shan Yin, Ming-Ming Su, Yan Ni, Jia Miao, Wen-Lin Wu, Hong Chen, Kim L. R. Brouwer, Chang-Xiao Liu, Liang Xu, Wei Jia and Ke Lan
      Drug Metabolism and Disposition March 2019, 47 (3) 283-294; DOI: https://doi.org/10.1124/dmd.118.085670

  2. Zhao, Jihui

    1. Hydrolytic Metabolism of Cyanopyrrolidine DPP-4 Inhibitors Mediated by Dipeptidyl Peptidases
      Fandi Kong, Xiaoyan Pang, Jihui Zhao, Pan Deng, Mingyue Zheng, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition March 2019, 47 (3) 238-248; DOI: https://doi.org/10.1124/dmd.118.084640

  3. Zheng, Mingyue

    1. Hydrolytic Metabolism of Cyanopyrrolidine DPP-4 Inhibitors Mediated by Dipeptidyl Peptidases
      Fandi Kong, Xiaoyan Pang, Jihui Zhao, Pan Deng, Mingyue Zheng, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition March 2019, 47 (3) 238-248; DOI: https://doi.org/10.1124/dmd.118.084640

  4. Zhong, Dafang

    1. Hydrolytic Metabolism of Cyanopyrrolidine DPP-4 Inhibitors Mediated by Dipeptidyl Peptidases
      Fandi Kong, Xiaoyan Pang, Jihui Zhao, Pan Deng, Mingyue Zheng, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition March 2019, 47 (3) 238-248; DOI: https://doi.org/10.1124/dmd.118.084640

  5. Zhu, Lijun

    1. Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide
      Yuhuan Li, Wenjie Song, Xiaojun Ou, Guangkuo Luo, Yushan Xie, Rongjin Sun, Ying Wang, Xiaoxiao Qi, Ming Hu, Zhongqiu Liu and Lijun Zhu
      Drug Metabolism and Disposition March 2019, 47 (3) 203-214; DOI: https://doi.org/10.1124/dmd.118.083493

  6. Zhu, Ping-Ping

    1. Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species
      Jian Zhang, Ling-Zhi Gao, Yu-Jie Chen, Ping-Ping Zhu, Shan-Shan Yin, Ming-Ming Su, Yan Ni, Jia Miao, Wen-Lin Wu, Hong Chen, Kim L. R. Brouwer, Chang-Xiao Liu, Liang Xu, Wei Jia and Ke Lan
      Drug Metabolism and Disposition March 2019, 47 (3) 283-294; DOI: https://doi.org/10.1124/dmd.118.085670
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