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Research ArticleArticle

Hepatocyte Concentrations of Imaging Compounds Associated with Transporter Inhibition: Evidence in Perfused Rat Livers

Pierre Bonnaventure, Fabien Cusin and Catherine M. Pastor
Drug Metabolism and Disposition April 2019, 47 (4) 412-418; DOI: https://doi.org/10.1124/dmd.118.084624
Pierre Bonnaventure
Department of Radiology, Hôpitaux Universitaires de Genève, Geneva, Switzerland (P.B., F.C., C.M.P.); and Laboratory of Imaging Biomarkers, Centre of Research on Inflammation, Unité Mixte de Recherche 1149, Institut National de la santé et de la Recherche Médicale and University Paris Diderot, Paris, France (C.M.P.)
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Fabien Cusin
Department of Radiology, Hôpitaux Universitaires de Genève, Geneva, Switzerland (P.B., F.C., C.M.P.); and Laboratory of Imaging Biomarkers, Centre of Research on Inflammation, Unité Mixte de Recherche 1149, Institut National de la santé et de la Recherche Médicale and University Paris Diderot, Paris, France (C.M.P.)
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Catherine M. Pastor
Department of Radiology, Hôpitaux Universitaires de Genève, Geneva, Switzerland (P.B., F.C., C.M.P.); and Laboratory of Imaging Biomarkers, Centre of Research on Inflammation, Unité Mixte de Recherche 1149, Institut National de la santé et de la Recherche Médicale and University Paris Diderot, Paris, France (C.M.P.)
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Article Information

vol. 47 no. 4 412-418
DOI 
https://doi.org/10.1124/dmd.118.084624
PubMed 
30674615

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received September 21, 2018
  • Accepted January 18, 2019
  • Published online March 7, 2019.

Article Versions

  • Earlier version (January 23, 2019 - 08:22).
  • Earlier version (January 25, 2019 - 08:41).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2019 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Pierre Bonnaventure,
  2. Fabien Cusin, and
  3. Catherine M. Pastor
  1. Department of Radiology, Hôpitaux Universitaires de Genève, Geneva, Switzerland (P.B., F.C., C.M.P.); and Laboratory of Imaging Biomarkers, Centre of Research on Inflammation, Unité Mixte de Recherche 1149, Institut National de la santé et de la Recherche Médicale and University Paris Diderot, Paris, France (C.M.P.)
  1. Address correspondence to:
    Dr. Catherine M. Pastor, Department of Radiology, Hôpitaux Universitaires de Genève, Rue Gabrielle-Perret-Gentil, 4, 1205 Geneva, Switzerland. E-mail: catherine.pastor{at}unige.ch
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Drug Metabolism and Disposition: 47 (4)
Drug Metabolism and Disposition
Vol. 47, Issue 4
1 Apr 2019
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Research ArticleArticle

Drug Hepatocyte Concentrations and Transporter Inhibition

Pierre Bonnaventure, Fabien Cusin and Catherine M. Pastor
Drug Metabolism and Disposition April 1, 2019, 47 (4) 412-418; DOI: https://doi.org/10.1124/dmd.118.084624

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Research ArticleArticle

Drug Hepatocyte Concentrations and Transporter Inhibition

Pierre Bonnaventure, Fabien Cusin and Catherine M. Pastor
Drug Metabolism and Disposition April 1, 2019, 47 (4) 412-418; DOI: https://doi.org/10.1124/dmd.118.084624
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