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Data Supplement
- Supplemental Data -
Supplemental Figure 1: Plasma concentration--time profiles in mouse, rat and dog.
Supplemental Figure 2: Plasma concentration--time profiles in humans for all doses.
Supplemental Figure 3: Median AUC (upper panel) and median Cmax (bottom panel) in plasma versus doses and day of treatment for the simulated PBPK model in humans.
- Supplemental Data -