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Effects of Epacadostat on Brain Extracellular Fluid Concentrations of Serotonin—an Intracerebral Microdialysis Study in Sprague-Dawley Rats

Yan Zhang, Kevin Bowman, Janet Maleski, Sharon Diamond and Swamy Yeleswaram
Drug Metabolism and Disposition July 2019, 47 (7) 710-714; DOI: https://doi.org/10.1124/dmd.118.084053

Article Information

vol. 47 no. 7 710-714
DOI 
https://doi.org/10.1124/dmd.118.084053
PubMed 
31010933
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received August 22, 2018
  • Accepted April 19, 2019
  • Published online May 31, 2019.

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Copyright & Usage 
Copyright © 2019 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Yan Zhang,
  2. Kevin Bowman,
  3. Janet Maleski,
  4. Sharon Diamond, and
  5. Swamy Yeleswaram
  1. Departments of Drug Metabolism Pharmacokinetics and Clinical Pharmacology (Y.Z., K.B., S.D., S.Y.), and Clinical Development (J.M.), Incyte Corporation, Wilmington, Delaware
  1. Address correspondence to:
    Dr. Yan Zhang, Incyte Corporation, 1801 Augustine Cutoff, Wilmington, DE 19803. E-mail: yzhang{at}incyte.com
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Rapid CommunicationShort Communication

Epacadostat Has No Effect on Brain Serotonin Concentration

Yan Zhang, Kevin Bowman, Janet Maleski, Sharon Diamond and Swamy Yeleswaram
Drug Metabolism and Disposition July 1, 2019, 47 (7) 710-714; DOI: https://doi.org/10.1124/dmd.118.084053
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