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Index by author

August 01, 2019; Volume 47,Issue 8

A

  1. Adusumalli, Sravani

    1. Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach
      Sravani Adusumalli, Rohitash Jamwal, R. Scott Obach, Tim F. Ryder, Lorenzo Leggio and Fatemeh Akhlaghi
      Drug Metabolism and Disposition August 2019, 47 (8) 874-882; DOI: https://doi.org/10.1124/dmd.119.087015

  2. Akhlaghi, Fatemeh

    1. Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach
      Sravani Adusumalli, Rohitash Jamwal, R. Scott Obach, Tim F. Ryder, Lorenzo Leggio and Fatemeh Akhlaghi
      Drug Metabolism and Disposition August 2019, 47 (8) 874-882; DOI: https://doi.org/10.1124/dmd.119.087015

B

  1. Bai, Ruifeng

    1. Enhanced Platelet Response to Clopidogrel in Zucker Diabetic Fatty Rats due to Impaired Clopidogrel Inactivation by Carboxylesterase 1 and Increased Exposure to Active Metabolite
      Enhanced Platelet Response to Clopidogrel in Zucker Diabetic Fatty Rats due to Impaired Clopidogrel Inactivation by Carboxylesterase 1 and Increased Exposure to Active Metabolite
      Hongwei Yao, Ruifeng Bai, Tianming Ren, Yani Wang, Jingkai Gu and Yingjie Guo
      Drug Metabolism and Disposition August 2019, 47 (8) 794-801; DOI: https://doi.org/10.1124/dmd.118.085126

  2. Basit, Abdul

    1. Kidney Cortical Transporter Expression across Species Using Quantitative Proteomics
      Abdul Basit, Zaher Radi, Vishal S. Vaidya, Matthew Karasu and Bhagwat Prasad
      Drug Metabolism and Disposition August 2019, 47 (8) 802-808; DOI: https://doi.org/10.1124/dmd.119.086579

  3. Beaudoin, James J.

    1. Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease
      Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease
      Jacqueline Bezençon, James J. Beaudoin, Katsuaki Ito, Dong Fu, Sharin E. Roth, William J. Brock and Kim L.R. Brouwer
      Drug Metabolism and Disposition August 2019, 47 (8) 899-906; DOI: https://doi.org/10.1124/dmd.119.086785

  4. Bezençon, Jacqueline

    1. Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease
      Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease
      Jacqueline Bezençon, James J. Beaudoin, Katsuaki Ito, Dong Fu, Sharin E. Roth, William J. Brock and Kim L.R. Brouwer
      Drug Metabolism and Disposition August 2019, 47 (8) 899-906; DOI: https://doi.org/10.1124/dmd.119.086785

  5. Bhatt, Deepak Kumar

    1. Ontogeny of Hepatic Sulfotransferases and Prediction of Age-Dependent Fractional Contribution of Sulfation in Acetaminophen Metabolism
      Mayur K. Ladumor, Deepak Kumar Bhatt, Andrea Gaedigk, Sheena Sharma, Aarzoo Thakur, Robin E. Pearce, J. Steven Leeder, Michael B. Bolger, Saranjit Singh and Bhagwat Prasad
      Drug Metabolism and Disposition August 2019, 47 (8) 818-831; DOI: https://doi.org/10.1124/dmd.119.086462

  6. Bolger, Michael B.

    1. Ontogeny of Hepatic Sulfotransferases and Prediction of Age-Dependent Fractional Contribution of Sulfation in Acetaminophen Metabolism
      Mayur K. Ladumor, Deepak Kumar Bhatt, Andrea Gaedigk, Sheena Sharma, Aarzoo Thakur, Robin E. Pearce, J. Steven Leeder, Michael B. Bolger, Saranjit Singh and Bhagwat Prasad
      Drug Metabolism and Disposition August 2019, 47 (8) 818-831; DOI: https://doi.org/10.1124/dmd.119.086462

  7. Brock, William J.

    1. Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease
      Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease
      Jacqueline Bezençon, James J. Beaudoin, Katsuaki Ito, Dong Fu, Sharin E. Roth, William J. Brock and Kim L.R. Brouwer
      Drug Metabolism and Disposition August 2019, 47 (8) 899-906; DOI: https://doi.org/10.1124/dmd.119.086785

  8. Brouwer, Kim L.R.

    1. Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease
      Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease
      Jacqueline Bezençon, James J. Beaudoin, Katsuaki Ito, Dong Fu, Sharin E. Roth, William J. Brock and Kim L.R. Brouwer
      Drug Metabolism and Disposition August 2019, 47 (8) 899-906; DOI: https://doi.org/10.1124/dmd.119.086785

C

  1. Chen, Jian-Lu

    1. Clinical Extrapolation of the Effects of Dolutegravir and Other HIV Integrase Inhibitors on Folate Transport Pathways
      Maciej J. Zamek-Gliszczynski, Xuexiang Zhang, Jennypher Mudunuru, Yewei Du, Jian-Lu Chen, Kunal S. Taskar, Jane Huang, Yong Huang and Elizabeth H. Romach
      Drug Metabolism and Disposition August 2019, 47 (8) 890-898; DOI: https://doi.org/10.1124/dmd.119.087635

  2. Chen, Weidong

    1. Activation of Pregnane X Receptor–Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo
      Activation of Pregnane X Receptor–Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo
      Fengling Wang, Huihui Wang, Yifan Wu, Lei Wang, Ling Zhang, Xi Ye, Daiyin Peng and Weidong Chen
      Drug Metabolism and Disposition August 2019, 47 (8) 785-793; DOI: https://doi.org/10.1124/dmd.119.086769

  3. Chen, Xiaoyan

    1. Carboxylesterase 2 and Intestine Transporters Contribute to the Low Bioavailability of Allisartan, a Prodrug of Exp3174 for Hypertension Treatment in Humans
      Xiuli Li, Jingchao Sun, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition August 2019, 47 (8) 843-853; DOI: https://doi.org/10.1124/dmd.118.085092

  4. Cox, Rhona J.

    1. Open Access
      Plasma Protein Binding as an Optimizable Parameter for Acidic Drugs
      Philip Gardiner, Rhona J. Cox and Ken Grime
      Drug Metabolism and Disposition August 2019, 47 (8) 865-873; DOI: https://doi.org/10.1124/dmd.119.087163

  5. Cui, Julia Yue

    1. Polybrominated Diphenyl Ethers and Gut Microbiome Modulate Metabolic Syndrome–Related Aqueous Metabolites in Mice
      David K. Scoville, Cindy Yanfei Li, Dongfang Wang, Joseph L. Dempsey, Daniel Raftery, Sridhar Mani, Haiwei Gu and Julia Yue Cui
      Drug Metabolism and Disposition August 2019, 47 (8) 928-940; DOI: https://doi.org/10.1124/dmd.119.086538

D

  1. Dela Cruz-Chuh, Josefa

    1. Carfilzomib Is Not an Appropriate Payload of Antibody-Drug Conjugates Due to Rapid Inactivation by Lysosomal Enzymes
      Yong Ma, Josefa Dela Cruz-Chuh, S. Cyrus Khojasteh, Peter S. Dragovich, Thomas H. Pillow and Donglu Zhang
      Drug Metabolism and Disposition August 2019, 47 (8) 884-889; DOI: https://doi.org/10.1124/dmd.119.086595

  2. Dempsey, Joseph L.

    1. Polybrominated Diphenyl Ethers and Gut Microbiome Modulate Metabolic Syndrome–Related Aqueous Metabolites in Mice
      David K. Scoville, Cindy Yanfei Li, Dongfang Wang, Joseph L. Dempsey, Daniel Raftery, Sridhar Mani, Haiwei Gu and Julia Yue Cui
      Drug Metabolism and Disposition August 2019, 47 (8) 928-940; DOI: https://doi.org/10.1124/dmd.119.086538

  3. Dragovich, Peter S.

    1. Carfilzomib Is Not an Appropriate Payload of Antibody-Drug Conjugates Due to Rapid Inactivation by Lysosomal Enzymes
      Yong Ma, Josefa Dela Cruz-Chuh, S. Cyrus Khojasteh, Peter S. Dragovich, Thomas H. Pillow and Donglu Zhang
      Drug Metabolism and Disposition August 2019, 47 (8) 884-889; DOI: https://doi.org/10.1124/dmd.119.086595

  4. Dresser, George K.

    1. Fexofenadine and Rosuvastatin Pharmacokinetics in Mice with Targeted Disruption of Organic Anion Transporting Polypeptide 2B1
      Samantha Medwid, Mandy M.J. Li, Michael J. Knauer, Kathleen Lin, Sara E. Mansell, Crystal L. Schmerk, Catherine Zhu, Katelyn E. Griffin, Mohamed D. Yousif, George K. Dresser, Ute I. Schwarz, Richard B. Kim and Rommel G. Tirona
      Drug Metabolism and Disposition August 2019, 47 (8) 832-842; DOI: https://doi.org/10.1124/dmd.119.087619

  5. Du, Yewei

    1. Clinical Extrapolation of the Effects of Dolutegravir and Other HIV Integrase Inhibitors on Folate Transport Pathways
      Maciej J. Zamek-Gliszczynski, Xuexiang Zhang, Jennypher Mudunuru, Yewei Du, Jian-Lu Chen, Kunal S. Taskar, Jane Huang, Yong Huang and Elizabeth H. Romach
      Drug Metabolism and Disposition August 2019, 47 (8) 890-898; DOI: https://doi.org/10.1124/dmd.119.087635

F

  1. Fu, Dong

    1. Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease
      Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease
      Jacqueline Bezençon, James J. Beaudoin, Katsuaki Ito, Dong Fu, Sharin E. Roth, William J. Brock and Kim L.R. Brouwer
      Drug Metabolism and Disposition August 2019, 47 (8) 899-906; DOI: https://doi.org/10.1124/dmd.119.086785

G

  1. Gaedigk, Andrea

    1. Ontogeny of Hepatic Sulfotransferases and Prediction of Age-Dependent Fractional Contribution of Sulfation in Acetaminophen Metabolism
      Mayur K. Ladumor, Deepak Kumar Bhatt, Andrea Gaedigk, Sheena Sharma, Aarzoo Thakur, Robin E. Pearce, J. Steven Leeder, Michael B. Bolger, Saranjit Singh and Bhagwat Prasad
      Drug Metabolism and Disposition August 2019, 47 (8) 818-831; DOI: https://doi.org/10.1124/dmd.119.086462

  2. Gardiner, Philip

    1. Open Access
      Plasma Protein Binding as an Optimizable Parameter for Acidic Drugs
      Philip Gardiner, Rhona J. Cox and Ken Grime
      Drug Metabolism and Disposition August 2019, 47 (8) 865-873; DOI: https://doi.org/10.1124/dmd.119.087163

  3. Griffin, Katelyn E.

    1. Fexofenadine and Rosuvastatin Pharmacokinetics in Mice with Targeted Disruption of Organic Anion Transporting Polypeptide 2B1
      Samantha Medwid, Mandy M.J. Li, Michael J. Knauer, Kathleen Lin, Sara E. Mansell, Crystal L. Schmerk, Catherine Zhu, Katelyn E. Griffin, Mohamed D. Yousif, George K. Dresser, Ute I. Schwarz, Richard B. Kim and Rommel G. Tirona
      Drug Metabolism and Disposition August 2019, 47 (8) 832-842; DOI: https://doi.org/10.1124/dmd.119.087619

  4. Grime, Ken

    1. Open Access
      Plasma Protein Binding as an Optimizable Parameter for Acidic Drugs
      Philip Gardiner, Rhona J. Cox and Ken Grime
      Drug Metabolism and Disposition August 2019, 47 (8) 865-873; DOI: https://doi.org/10.1124/dmd.119.087163

  5. Gu, Haiwei

    1. Polybrominated Diphenyl Ethers and Gut Microbiome Modulate Metabolic Syndrome–Related Aqueous Metabolites in Mice
      David K. Scoville, Cindy Yanfei Li, Dongfang Wang, Joseph L. Dempsey, Daniel Raftery, Sridhar Mani, Haiwei Gu and Julia Yue Cui
      Drug Metabolism and Disposition August 2019, 47 (8) 928-940; DOI: https://doi.org/10.1124/dmd.119.086538

  6. Gu, Jingkai

    1. Enhanced Platelet Response to Clopidogrel in Zucker Diabetic Fatty Rats due to Impaired Clopidogrel Inactivation by Carboxylesterase 1 and Increased Exposure to Active Metabolite
      Enhanced Platelet Response to Clopidogrel in Zucker Diabetic Fatty Rats due to Impaired Clopidogrel Inactivation by Carboxylesterase 1 and Increased Exposure to Active Metabolite
      Hongwei Yao, Ruifeng Bai, Tianming Ren, Yani Wang, Jingkai Gu and Yingjie Guo
      Drug Metabolism and Disposition August 2019, 47 (8) 794-801; DOI: https://doi.org/10.1124/dmd.118.085126

  7. Guo, Yingjie

    1. Enhanced Platelet Response to Clopidogrel in Zucker Diabetic Fatty Rats due to Impaired Clopidogrel Inactivation by Carboxylesterase 1 and Increased Exposure to Active Metabolite
      Enhanced Platelet Response to Clopidogrel in Zucker Diabetic Fatty Rats due to Impaired Clopidogrel Inactivation by Carboxylesterase 1 and Increased Exposure to Active Metabolite
      Hongwei Yao, Ruifeng Bai, Tianming Ren, Yani Wang, Jingkai Gu and Yingjie Guo
      Drug Metabolism and Disposition August 2019, 47 (8) 794-801; DOI: https://doi.org/10.1124/dmd.118.085126

  8. Guo, Zitao

    1. Carboxylesterase 2 and Intestine Transporters Contribute to the Low Bioavailability of Allisartan, a Prodrug of Exp3174 for Hypertension Treatment in Humans
      Xiuli Li, Jingchao Sun, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition August 2019, 47 (8) 843-853; DOI: https://doi.org/10.1124/dmd.118.085092

H

  1. Harwood, Matthew D.

    1. The Regional-Specific Relative and Absolute Expression of Gut Transporters in Adult Caucasians: A Meta-Analysis
      Open Access
      The Regional-Specific Relative and Absolute Expression of Gut Transporters in Adult Caucasians: A Meta-Analysis
      Matthew D. Harwood, Mian Zhang, Shriram M. Pathak and Sibylle Neuhoff
      Drug Metabolism and Disposition August 2019, 47 (8) 854-864; DOI: https://doi.org/10.1124/dmd.119.086959

  2. Henderson, C. J.

    1. Open Access
      Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice
      Y. Kapelyukh, C. J. Henderson, N. Scheer, A. Rode and C. R. Wolf
      Drug Metabolism and Disposition August 2019, 47 (8) 907-918; DOI: https://doi.org/10.1124/dmd.119.087718

  3. Huang, Jane

    1. Clinical Extrapolation of the Effects of Dolutegravir and Other HIV Integrase Inhibitors on Folate Transport Pathways
      Maciej J. Zamek-Gliszczynski, Xuexiang Zhang, Jennypher Mudunuru, Yewei Du, Jian-Lu Chen, Kunal S. Taskar, Jane Huang, Yong Huang and Elizabeth H. Romach
      Drug Metabolism and Disposition August 2019, 47 (8) 890-898; DOI: https://doi.org/10.1124/dmd.119.087635

  4. Huang, Yong

    1. Clinical Extrapolation of the Effects of Dolutegravir and Other HIV Integrase Inhibitors on Folate Transport Pathways
      Maciej J. Zamek-Gliszczynski, Xuexiang Zhang, Jennypher Mudunuru, Yewei Du, Jian-Lu Chen, Kunal S. Taskar, Jane Huang, Yong Huang and Elizabeth H. Romach
      Drug Metabolism and Disposition August 2019, 47 (8) 890-898; DOI: https://doi.org/10.1124/dmd.119.087635

I

  1. Ito, Katsuaki

    1. Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease
      Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease
      Jacqueline Bezençon, James J. Beaudoin, Katsuaki Ito, Dong Fu, Sharin E. Roth, William J. Brock and Kim L.R. Brouwer
      Drug Metabolism and Disposition August 2019, 47 (8) 899-906; DOI: https://doi.org/10.1124/dmd.119.086785

J

  1. Jamwal, Rohitash

    1. Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach
      Sravani Adusumalli, Rohitash Jamwal, R. Scott Obach, Tim F. Ryder, Lorenzo Leggio and Fatemeh Akhlaghi
      Drug Metabolism and Disposition August 2019, 47 (8) 874-882; DOI: https://doi.org/10.1124/dmd.119.087015

K

  1. Kapelyukh, Y.

    1. Open Access
      Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice
      Y. Kapelyukh, C. J. Henderson, N. Scheer, A. Rode and C. R. Wolf
      Drug Metabolism and Disposition August 2019, 47 (8) 907-918; DOI: https://doi.org/10.1124/dmd.119.087718

  2. Karasu, Matthew

    1. Kidney Cortical Transporter Expression across Species Using Quantitative Proteomics
      Abdul Basit, Zaher Radi, Vishal S. Vaidya, Matthew Karasu and Bhagwat Prasad
      Drug Metabolism and Disposition August 2019, 47 (8) 802-808; DOI: https://doi.org/10.1124/dmd.119.086579

  3. Khojasteh, S. Cyrus

    1. Carfilzomib Is Not an Appropriate Payload of Antibody-Drug Conjugates Due to Rapid Inactivation by Lysosomal Enzymes
      Yong Ma, Josefa Dela Cruz-Chuh, S. Cyrus Khojasteh, Peter S. Dragovich, Thomas H. Pillow and Donglu Zhang
      Drug Metabolism and Disposition August 2019, 47 (8) 884-889; DOI: https://doi.org/10.1124/dmd.119.086595

  4. Kim, Richard B.

    1. Fexofenadine and Rosuvastatin Pharmacokinetics in Mice with Targeted Disruption of Organic Anion Transporting Polypeptide 2B1
      Samantha Medwid, Mandy M.J. Li, Michael J. Knauer, Kathleen Lin, Sara E. Mansell, Crystal L. Schmerk, Catherine Zhu, Katelyn E. Griffin, Mohamed D. Yousif, George K. Dresser, Ute I. Schwarz, Richard B. Kim and Rommel G. Tirona
      Drug Metabolism and Disposition August 2019, 47 (8) 832-842; DOI: https://doi.org/10.1124/dmd.119.087619

  5. Knauer, Michael J.

    1. Fexofenadine and Rosuvastatin Pharmacokinetics in Mice with Targeted Disruption of Organic Anion Transporting Polypeptide 2B1
      Samantha Medwid, Mandy M.J. Li, Michael J. Knauer, Kathleen Lin, Sara E. Mansell, Crystal L. Schmerk, Catherine Zhu, Katelyn E. Griffin, Mohamed D. Yousif, George K. Dresser, Ute I. Schwarz, Richard B. Kim and Rommel G. Tirona
      Drug Metabolism and Disposition August 2019, 47 (8) 832-842; DOI: https://doi.org/10.1124/dmd.119.087619

L

  1. Ladumor, Mayur K.

    1. Ontogeny of Hepatic Sulfotransferases and Prediction of Age-Dependent Fractional Contribution of Sulfation in Acetaminophen Metabolism
      Mayur K. Ladumor, Deepak Kumar Bhatt, Andrea Gaedigk, Sheena Sharma, Aarzoo Thakur, Robin E. Pearce, J. Steven Leeder, Michael B. Bolger, Saranjit Singh and Bhagwat Prasad
      Drug Metabolism and Disposition August 2019, 47 (8) 818-831; DOI: https://doi.org/10.1124/dmd.119.086462

  2. Leeder, J. Steven

    1. Ontogeny of Hepatic Sulfotransferases and Prediction of Age-Dependent Fractional Contribution of Sulfation in Acetaminophen Metabolism
      Mayur K. Ladumor, Deepak Kumar Bhatt, Andrea Gaedigk, Sheena Sharma, Aarzoo Thakur, Robin E. Pearce, J. Steven Leeder, Michael B. Bolger, Saranjit Singh and Bhagwat Prasad
      Drug Metabolism and Disposition August 2019, 47 (8) 818-831; DOI: https://doi.org/10.1124/dmd.119.086462

  3. Leggio, Lorenzo

    1. Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach
      Sravani Adusumalli, Rohitash Jamwal, R. Scott Obach, Tim F. Ryder, Lorenzo Leggio and Fatemeh Akhlaghi
      Drug Metabolism and Disposition August 2019, 47 (8) 874-882; DOI: https://doi.org/10.1124/dmd.119.087015

  4. Li, Cindy Yanfei

    1. Polybrominated Diphenyl Ethers and Gut Microbiome Modulate Metabolic Syndrome–Related Aqueous Metabolites in Mice
      David K. Scoville, Cindy Yanfei Li, Dongfang Wang, Joseph L. Dempsey, Daniel Raftery, Sridhar Mani, Haiwei Gu and Julia Yue Cui
      Drug Metabolism and Disposition August 2019, 47 (8) 928-940; DOI: https://doi.org/10.1124/dmd.119.086538

  5. Li, Mandy M.J.

    1. Fexofenadine and Rosuvastatin Pharmacokinetics in Mice with Targeted Disruption of Organic Anion Transporting Polypeptide 2B1
      Samantha Medwid, Mandy M.J. Li, Michael J. Knauer, Kathleen Lin, Sara E. Mansell, Crystal L. Schmerk, Catherine Zhu, Katelyn E. Griffin, Mohamed D. Yousif, George K. Dresser, Ute I. Schwarz, Richard B. Kim and Rommel G. Tirona
      Drug Metabolism and Disposition August 2019, 47 (8) 832-842; DOI: https://doi.org/10.1124/dmd.119.087619

  6. Li, Xiuli

    1. Carboxylesterase 2 and Intestine Transporters Contribute to the Low Bioavailability of Allisartan, a Prodrug of Exp3174 for Hypertension Treatment in Humans
      Xiuli Li, Jingchao Sun, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition August 2019, 47 (8) 843-853; DOI: https://doi.org/10.1124/dmd.118.085092

  7. Li, Yilin

    1. Nitidine Chloride–Induced CYP1 Enzyme Inhibition and Alteration of Estradiol Metabolism
      Xu Mao, Jian Wang, Qian Wang, Lan Yang, Yilin Li, Hao Lin, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition August 2019, 47 (8) 919-927; DOI: https://doi.org/10.1124/dmd.119.086892

  8. Lin, Hao

    1. Nitidine Chloride–Induced CYP1 Enzyme Inhibition and Alteration of Estradiol Metabolism
      Xu Mao, Jian Wang, Qian Wang, Lan Yang, Yilin Li, Hao Lin, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition August 2019, 47 (8) 919-927; DOI: https://doi.org/10.1124/dmd.119.086892

  9. Lin, Kathleen

    1. Fexofenadine and Rosuvastatin Pharmacokinetics in Mice with Targeted Disruption of Organic Anion Transporting Polypeptide 2B1
      Samantha Medwid, Mandy M.J. Li, Michael J. Knauer, Kathleen Lin, Sara E. Mansell, Crystal L. Schmerk, Catherine Zhu, Katelyn E. Griffin, Mohamed D. Yousif, George K. Dresser, Ute I. Schwarz, Richard B. Kim and Rommel G. Tirona
      Drug Metabolism and Disposition August 2019, 47 (8) 832-842; DOI: https://doi.org/10.1124/dmd.119.087619

M

  1. Ma, Yong

    1. Carfilzomib Is Not an Appropriate Payload of Antibody-Drug Conjugates Due to Rapid Inactivation by Lysosomal Enzymes
      Yong Ma, Josefa Dela Cruz-Chuh, S. Cyrus Khojasteh, Peter S. Dragovich, Thomas H. Pillow and Donglu Zhang
      Drug Metabolism and Disposition August 2019, 47 (8) 884-889; DOI: https://doi.org/10.1124/dmd.119.086595

  2. Mani, Sridhar

    1. Polybrominated Diphenyl Ethers and Gut Microbiome Modulate Metabolic Syndrome–Related Aqueous Metabolites in Mice
      David K. Scoville, Cindy Yanfei Li, Dongfang Wang, Joseph L. Dempsey, Daniel Raftery, Sridhar Mani, Haiwei Gu and Julia Yue Cui
      Drug Metabolism and Disposition August 2019, 47 (8) 928-940; DOI: https://doi.org/10.1124/dmd.119.086538

  3. Mansell, Sara E.

    1. Fexofenadine and Rosuvastatin Pharmacokinetics in Mice with Targeted Disruption of Organic Anion Transporting Polypeptide 2B1
      Samantha Medwid, Mandy M.J. Li, Michael J. Knauer, Kathleen Lin, Sara E. Mansell, Crystal L. Schmerk, Catherine Zhu, Katelyn E. Griffin, Mohamed D. Yousif, George K. Dresser, Ute I. Schwarz, Richard B. Kim and Rommel G. Tirona
      Drug Metabolism and Disposition August 2019, 47 (8) 832-842; DOI: https://doi.org/10.1124/dmd.119.087619

  4. Mao, Xu

    1. Nitidine Chloride–Induced CYP1 Enzyme Inhibition and Alteration of Estradiol Metabolism
      Xu Mao, Jian Wang, Qian Wang, Lan Yang, Yilin Li, Hao Lin, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition August 2019, 47 (8) 919-927; DOI: https://doi.org/10.1124/dmd.119.086892

  5. Medwid, Samantha

    1. Fexofenadine and Rosuvastatin Pharmacokinetics in Mice with Targeted Disruption of Organic Anion Transporting Polypeptide 2B1
      Samantha Medwid, Mandy M.J. Li, Michael J. Knauer, Kathleen Lin, Sara E. Mansell, Crystal L. Schmerk, Catherine Zhu, Katelyn E. Griffin, Mohamed D. Yousif, George K. Dresser, Ute I. Schwarz, Richard B. Kim and Rommel G. Tirona
      Drug Metabolism and Disposition August 2019, 47 (8) 832-842; DOI: https://doi.org/10.1124/dmd.119.087619

  6. Mizuno, Katsuhiko

    1. Identification of Novel Metabolites of Vildagliptin in Rats: Thiazoline-Containing Thiol Adducts Formed via Cysteine or Glutathione Conjugation
      Katsuhiko Mizuno, Kenji Takeuchi, Ken Umehara and Miki Nakajima
      Drug Metabolism and Disposition August 2019, 47 (8) 809-817; DOI: https://doi.org/10.1124/dmd.119.086546

  7. Mudunuru, Jennypher

    1. Clinical Extrapolation of the Effects of Dolutegravir and Other HIV Integrase Inhibitors on Folate Transport Pathways
      Maciej J. Zamek-Gliszczynski, Xuexiang Zhang, Jennypher Mudunuru, Yewei Du, Jian-Lu Chen, Kunal S. Taskar, Jane Huang, Yong Huang and Elizabeth H. Romach
      Drug Metabolism and Disposition August 2019, 47 (8) 890-898; DOI: https://doi.org/10.1124/dmd.119.087635

N

  1. Nakajima, Miki

    1. Identification of Novel Metabolites of Vildagliptin in Rats: Thiazoline-Containing Thiol Adducts Formed via Cysteine or Glutathione Conjugation
      Katsuhiko Mizuno, Kenji Takeuchi, Ken Umehara and Miki Nakajima
      Drug Metabolism and Disposition August 2019, 47 (8) 809-817; DOI: https://doi.org/10.1124/dmd.119.086546

  2. Neuhoff, Sibylle

    1. The Regional-Specific Relative and Absolute Expression of Gut Transporters in Adult Caucasians: A Meta-Analysis
      Open Access
      The Regional-Specific Relative and Absolute Expression of Gut Transporters in Adult Caucasians: A Meta-Analysis
      Matthew D. Harwood, Mian Zhang, Shriram M. Pathak and Sibylle Neuhoff
      Drug Metabolism and Disposition August 2019, 47 (8) 854-864; DOI: https://doi.org/10.1124/dmd.119.086959

O

  1. Obach, R. Scott

    1. Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach
      Sravani Adusumalli, Rohitash Jamwal, R. Scott Obach, Tim F. Ryder, Lorenzo Leggio and Fatemeh Akhlaghi
      Drug Metabolism and Disposition August 2019, 47 (8) 874-882; DOI: https://doi.org/10.1124/dmd.119.087015

P

  1. Pathak, Shriram M.

    1. The Regional-Specific Relative and Absolute Expression of Gut Transporters in Adult Caucasians: A Meta-Analysis
      Open Access
      The Regional-Specific Relative and Absolute Expression of Gut Transporters in Adult Caucasians: A Meta-Analysis
      Matthew D. Harwood, Mian Zhang, Shriram M. Pathak and Sibylle Neuhoff
      Drug Metabolism and Disposition August 2019, 47 (8) 854-864; DOI: https://doi.org/10.1124/dmd.119.086959

  2. Pearce, Robin E.

    1. Ontogeny of Hepatic Sulfotransferases and Prediction of Age-Dependent Fractional Contribution of Sulfation in Acetaminophen Metabolism
      Mayur K. Ladumor, Deepak Kumar Bhatt, Andrea Gaedigk, Sheena Sharma, Aarzoo Thakur, Robin E. Pearce, J. Steven Leeder, Michael B. Bolger, Saranjit Singh and Bhagwat Prasad
      Drug Metabolism and Disposition August 2019, 47 (8) 818-831; DOI: https://doi.org/10.1124/dmd.119.086462

  3. Peng, Daiyin

    1. Activation of Pregnane X Receptor–Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo
      Activation of Pregnane X Receptor–Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo
      Fengling Wang, Huihui Wang, Yifan Wu, Lei Wang, Ling Zhang, Xi Ye, Daiyin Peng and Weidong Chen
      Drug Metabolism and Disposition August 2019, 47 (8) 785-793; DOI: https://doi.org/10.1124/dmd.119.086769

  4. Peng, Ying

    1. Nitidine Chloride–Induced CYP1 Enzyme Inhibition and Alteration of Estradiol Metabolism
      Xu Mao, Jian Wang, Qian Wang, Lan Yang, Yilin Li, Hao Lin, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition August 2019, 47 (8) 919-927; DOI: https://doi.org/10.1124/dmd.119.086892

  5. Pillow, Thomas H.

    1. Carfilzomib Is Not an Appropriate Payload of Antibody-Drug Conjugates Due to Rapid Inactivation by Lysosomal Enzymes
      Yong Ma, Josefa Dela Cruz-Chuh, S. Cyrus Khojasteh, Peter S. Dragovich, Thomas H. Pillow and Donglu Zhang
      Drug Metabolism and Disposition August 2019, 47 (8) 884-889; DOI: https://doi.org/10.1124/dmd.119.086595

  6. Prasad, Bhagwat

    1. Kidney Cortical Transporter Expression across Species Using Quantitative Proteomics
      Abdul Basit, Zaher Radi, Vishal S. Vaidya, Matthew Karasu and Bhagwat Prasad
      Drug Metabolism and Disposition August 2019, 47 (8) 802-808; DOI: https://doi.org/10.1124/dmd.119.086579
    2. Ontogeny of Hepatic Sulfotransferases and Prediction of Age-Dependent Fractional Contribution of Sulfation in Acetaminophen Metabolism
      Mayur K. Ladumor, Deepak Kumar Bhatt, Andrea Gaedigk, Sheena Sharma, Aarzoo Thakur, Robin E. Pearce, J. Steven Leeder, Michael B. Bolger, Saranjit Singh and Bhagwat Prasad
      Drug Metabolism and Disposition August 2019, 47 (8) 818-831; DOI: https://doi.org/10.1124/dmd.119.086462

R

  1. Radi, Zaher

    1. Kidney Cortical Transporter Expression across Species Using Quantitative Proteomics
      Abdul Basit, Zaher Radi, Vishal S. Vaidya, Matthew Karasu and Bhagwat Prasad
      Drug Metabolism and Disposition August 2019, 47 (8) 802-808; DOI: https://doi.org/10.1124/dmd.119.086579

  2. Raftery, Daniel

    1. Polybrominated Diphenyl Ethers and Gut Microbiome Modulate Metabolic Syndrome–Related Aqueous Metabolites in Mice
      David K. Scoville, Cindy Yanfei Li, Dongfang Wang, Joseph L. Dempsey, Daniel Raftery, Sridhar Mani, Haiwei Gu and Julia Yue Cui
      Drug Metabolism and Disposition August 2019, 47 (8) 928-940; DOI: https://doi.org/10.1124/dmd.119.086538

  3. Ren, Tianming

    1. Enhanced Platelet Response to Clopidogrel in Zucker Diabetic Fatty Rats due to Impaired Clopidogrel Inactivation by Carboxylesterase 1 and Increased Exposure to Active Metabolite
      Enhanced Platelet Response to Clopidogrel in Zucker Diabetic Fatty Rats due to Impaired Clopidogrel Inactivation by Carboxylesterase 1 and Increased Exposure to Active Metabolite
      Hongwei Yao, Ruifeng Bai, Tianming Ren, Yani Wang, Jingkai Gu and Yingjie Guo
      Drug Metabolism and Disposition August 2019, 47 (8) 794-801; DOI: https://doi.org/10.1124/dmd.118.085126

  4. Rode, A.

    1. Open Access
      Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice
      Y. Kapelyukh, C. J. Henderson, N. Scheer, A. Rode and C. R. Wolf
      Drug Metabolism and Disposition August 2019, 47 (8) 907-918; DOI: https://doi.org/10.1124/dmd.119.087718

  5. Romach, Elizabeth H.

    1. Clinical Extrapolation of the Effects of Dolutegravir and Other HIV Integrase Inhibitors on Folate Transport Pathways
      Maciej J. Zamek-Gliszczynski, Xuexiang Zhang, Jennypher Mudunuru, Yewei Du, Jian-Lu Chen, Kunal S. Taskar, Jane Huang, Yong Huang and Elizabeth H. Romach
      Drug Metabolism and Disposition August 2019, 47 (8) 890-898; DOI: https://doi.org/10.1124/dmd.119.087635

  6. Roth, Sharin E.

    1. Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease
      Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease
      Jacqueline Bezençon, James J. Beaudoin, Katsuaki Ito, Dong Fu, Sharin E. Roth, William J. Brock and Kim L.R. Brouwer
      Drug Metabolism and Disposition August 2019, 47 (8) 899-906; DOI: https://doi.org/10.1124/dmd.119.086785

  7. Ryder, Tim F.

    1. Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach
      Sravani Adusumalli, Rohitash Jamwal, R. Scott Obach, Tim F. Ryder, Lorenzo Leggio and Fatemeh Akhlaghi
      Drug Metabolism and Disposition August 2019, 47 (8) 874-882; DOI: https://doi.org/10.1124/dmd.119.087015

S

  1. Scheer, N.

    1. Open Access
      Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice
      Y. Kapelyukh, C. J. Henderson, N. Scheer, A. Rode and C. R. Wolf
      Drug Metabolism and Disposition August 2019, 47 (8) 907-918; DOI: https://doi.org/10.1124/dmd.119.087718

  2. Schmerk, Crystal L.

    1. Fexofenadine and Rosuvastatin Pharmacokinetics in Mice with Targeted Disruption of Organic Anion Transporting Polypeptide 2B1
      Samantha Medwid, Mandy M.J. Li, Michael J. Knauer, Kathleen Lin, Sara E. Mansell, Crystal L. Schmerk, Catherine Zhu, Katelyn E. Griffin, Mohamed D. Yousif, George K. Dresser, Ute I. Schwarz, Richard B. Kim and Rommel G. Tirona
      Drug Metabolism and Disposition August 2019, 47 (8) 832-842; DOI: https://doi.org/10.1124/dmd.119.087619

  3. Schwarz, Ute I.

    1. Fexofenadine and Rosuvastatin Pharmacokinetics in Mice with Targeted Disruption of Organic Anion Transporting Polypeptide 2B1
      Samantha Medwid, Mandy M.J. Li, Michael J. Knauer, Kathleen Lin, Sara E. Mansell, Crystal L. Schmerk, Catherine Zhu, Katelyn E. Griffin, Mohamed D. Yousif, George K. Dresser, Ute I. Schwarz, Richard B. Kim and Rommel G. Tirona
      Drug Metabolism and Disposition August 2019, 47 (8) 832-842; DOI: https://doi.org/10.1124/dmd.119.087619

  4. Scoville, David K.

    1. Polybrominated Diphenyl Ethers and Gut Microbiome Modulate Metabolic Syndrome–Related Aqueous Metabolites in Mice
      David K. Scoville, Cindy Yanfei Li, Dongfang Wang, Joseph L. Dempsey, Daniel Raftery, Sridhar Mani, Haiwei Gu and Julia Yue Cui
      Drug Metabolism and Disposition August 2019, 47 (8) 928-940; DOI: https://doi.org/10.1124/dmd.119.086538

  5. Sharma, Sheena

    1. Ontogeny of Hepatic Sulfotransferases and Prediction of Age-Dependent Fractional Contribution of Sulfation in Acetaminophen Metabolism
      Mayur K. Ladumor, Deepak Kumar Bhatt, Andrea Gaedigk, Sheena Sharma, Aarzoo Thakur, Robin E. Pearce, J. Steven Leeder, Michael B. Bolger, Saranjit Singh and Bhagwat Prasad
      Drug Metabolism and Disposition August 2019, 47 (8) 818-831; DOI: https://doi.org/10.1124/dmd.119.086462

  6. Singh, Saranjit

    1. Ontogeny of Hepatic Sulfotransferases and Prediction of Age-Dependent Fractional Contribution of Sulfation in Acetaminophen Metabolism
      Mayur K. Ladumor, Deepak Kumar Bhatt, Andrea Gaedigk, Sheena Sharma, Aarzoo Thakur, Robin E. Pearce, J. Steven Leeder, Michael B. Bolger, Saranjit Singh and Bhagwat Prasad
      Drug Metabolism and Disposition August 2019, 47 (8) 818-831; DOI: https://doi.org/10.1124/dmd.119.086462

  7. Sun, Jingchao

    1. Carboxylesterase 2 and Intestine Transporters Contribute to the Low Bioavailability of Allisartan, a Prodrug of Exp3174 for Hypertension Treatment in Humans
      Xiuli Li, Jingchao Sun, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition August 2019, 47 (8) 843-853; DOI: https://doi.org/10.1124/dmd.118.085092

T

  1. Takeuchi, Kenji

    1. Identification of Novel Metabolites of Vildagliptin in Rats: Thiazoline-Containing Thiol Adducts Formed via Cysteine or Glutathione Conjugation
      Katsuhiko Mizuno, Kenji Takeuchi, Ken Umehara and Miki Nakajima
      Drug Metabolism and Disposition August 2019, 47 (8) 809-817; DOI: https://doi.org/10.1124/dmd.119.086546

  2. Taskar, Kunal S.

    1. Clinical Extrapolation of the Effects of Dolutegravir and Other HIV Integrase Inhibitors on Folate Transport Pathways
      Maciej J. Zamek-Gliszczynski, Xuexiang Zhang, Jennypher Mudunuru, Yewei Du, Jian-Lu Chen, Kunal S. Taskar, Jane Huang, Yong Huang and Elizabeth H. Romach
      Drug Metabolism and Disposition August 2019, 47 (8) 890-898; DOI: https://doi.org/10.1124/dmd.119.087635

  3. Thakur, Aarzoo

    1. Ontogeny of Hepatic Sulfotransferases and Prediction of Age-Dependent Fractional Contribution of Sulfation in Acetaminophen Metabolism
      Mayur K. Ladumor, Deepak Kumar Bhatt, Andrea Gaedigk, Sheena Sharma, Aarzoo Thakur, Robin E. Pearce, J. Steven Leeder, Michael B. Bolger, Saranjit Singh and Bhagwat Prasad
      Drug Metabolism and Disposition August 2019, 47 (8) 818-831; DOI: https://doi.org/10.1124/dmd.119.086462

  4. Tirona, Rommel G.

    1. Fexofenadine and Rosuvastatin Pharmacokinetics in Mice with Targeted Disruption of Organic Anion Transporting Polypeptide 2B1
      Samantha Medwid, Mandy M.J. Li, Michael J. Knauer, Kathleen Lin, Sara E. Mansell, Crystal L. Schmerk, Catherine Zhu, Katelyn E. Griffin, Mohamed D. Yousif, George K. Dresser, Ute I. Schwarz, Richard B. Kim and Rommel G. Tirona
      Drug Metabolism and Disposition August 2019, 47 (8) 832-842; DOI: https://doi.org/10.1124/dmd.119.087619

U

  1. Umehara, Ken

    1. Identification of Novel Metabolites of Vildagliptin in Rats: Thiazoline-Containing Thiol Adducts Formed via Cysteine or Glutathione Conjugation
      Katsuhiko Mizuno, Kenji Takeuchi, Ken Umehara and Miki Nakajima
      Drug Metabolism and Disposition August 2019, 47 (8) 809-817; DOI: https://doi.org/10.1124/dmd.119.086546

V

  1. Vaidya, Vishal S.

    1. Kidney Cortical Transporter Expression across Species Using Quantitative Proteomics
      Abdul Basit, Zaher Radi, Vishal S. Vaidya, Matthew Karasu and Bhagwat Prasad
      Drug Metabolism and Disposition August 2019, 47 (8) 802-808; DOI: https://doi.org/10.1124/dmd.119.086579

W

  1. Wang, Dongfang

    1. Polybrominated Diphenyl Ethers and Gut Microbiome Modulate Metabolic Syndrome–Related Aqueous Metabolites in Mice
      David K. Scoville, Cindy Yanfei Li, Dongfang Wang, Joseph L. Dempsey, Daniel Raftery, Sridhar Mani, Haiwei Gu and Julia Yue Cui
      Drug Metabolism and Disposition August 2019, 47 (8) 928-940; DOI: https://doi.org/10.1124/dmd.119.086538

  2. Wang, Fengling

    1. Activation of Pregnane X Receptor–Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo
      Activation of Pregnane X Receptor–Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo
      Fengling Wang, Huihui Wang, Yifan Wu, Lei Wang, Ling Zhang, Xi Ye, Daiyin Peng and Weidong Chen
      Drug Metabolism and Disposition August 2019, 47 (8) 785-793; DOI: https://doi.org/10.1124/dmd.119.086769

  3. Wang, Huihui

    1. Activation of Pregnane X Receptor–Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo
      Activation of Pregnane X Receptor–Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo
      Fengling Wang, Huihui Wang, Yifan Wu, Lei Wang, Ling Zhang, Xi Ye, Daiyin Peng and Weidong Chen
      Drug Metabolism and Disposition August 2019, 47 (8) 785-793; DOI: https://doi.org/10.1124/dmd.119.086769

  4. Wang, Jian

    1. Nitidine Chloride–Induced CYP1 Enzyme Inhibition and Alteration of Estradiol Metabolism
      Xu Mao, Jian Wang, Qian Wang, Lan Yang, Yilin Li, Hao Lin, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition August 2019, 47 (8) 919-927; DOI: https://doi.org/10.1124/dmd.119.086892

  5. Wang, Lei

    1. Activation of Pregnane X Receptor–Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo
      Activation of Pregnane X Receptor–Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo
      Fengling Wang, Huihui Wang, Yifan Wu, Lei Wang, Ling Zhang, Xi Ye, Daiyin Peng and Weidong Chen
      Drug Metabolism and Disposition August 2019, 47 (8) 785-793; DOI: https://doi.org/10.1124/dmd.119.086769

  6. Wang, Qian

    1. Nitidine Chloride–Induced CYP1 Enzyme Inhibition and Alteration of Estradiol Metabolism
      Xu Mao, Jian Wang, Qian Wang, Lan Yang, Yilin Li, Hao Lin, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition August 2019, 47 (8) 919-927; DOI: https://doi.org/10.1124/dmd.119.086892

  7. Wang, Yani

    1. Enhanced Platelet Response to Clopidogrel in Zucker Diabetic Fatty Rats due to Impaired Clopidogrel Inactivation by Carboxylesterase 1 and Increased Exposure to Active Metabolite
      Enhanced Platelet Response to Clopidogrel in Zucker Diabetic Fatty Rats due to Impaired Clopidogrel Inactivation by Carboxylesterase 1 and Increased Exposure to Active Metabolite
      Hongwei Yao, Ruifeng Bai, Tianming Ren, Yani Wang, Jingkai Gu and Yingjie Guo
      Drug Metabolism and Disposition August 2019, 47 (8) 794-801; DOI: https://doi.org/10.1124/dmd.118.085126

  8. Wolf, C. R.

    1. Open Access
      Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice
      Y. Kapelyukh, C. J. Henderson, N. Scheer, A. Rode and C. R. Wolf
      Drug Metabolism and Disposition August 2019, 47 (8) 907-918; DOI: https://doi.org/10.1124/dmd.119.087718

  9. Wu, Yifan

    1. Activation of Pregnane X Receptor–Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo
      Activation of Pregnane X Receptor–Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo
      Fengling Wang, Huihui Wang, Yifan Wu, Lei Wang, Ling Zhang, Xi Ye, Daiyin Peng and Weidong Chen
      Drug Metabolism and Disposition August 2019, 47 (8) 785-793; DOI: https://doi.org/10.1124/dmd.119.086769

Y

  1. Yang, Lan

    1. Nitidine Chloride–Induced CYP1 Enzyme Inhibition and Alteration of Estradiol Metabolism
      Xu Mao, Jian Wang, Qian Wang, Lan Yang, Yilin Li, Hao Lin, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition August 2019, 47 (8) 919-927; DOI: https://doi.org/10.1124/dmd.119.086892

  2. Yao, Hongwei

    1. Enhanced Platelet Response to Clopidogrel in Zucker Diabetic Fatty Rats due to Impaired Clopidogrel Inactivation by Carboxylesterase 1 and Increased Exposure to Active Metabolite
      Enhanced Platelet Response to Clopidogrel in Zucker Diabetic Fatty Rats due to Impaired Clopidogrel Inactivation by Carboxylesterase 1 and Increased Exposure to Active Metabolite
      Hongwei Yao, Ruifeng Bai, Tianming Ren, Yani Wang, Jingkai Gu and Yingjie Guo
      Drug Metabolism and Disposition August 2019, 47 (8) 794-801; DOI: https://doi.org/10.1124/dmd.118.085126

  3. Ye, Xi

    1. Activation of Pregnane X Receptor–Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo
      Activation of Pregnane X Receptor–Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo
      Fengling Wang, Huihui Wang, Yifan Wu, Lei Wang, Ling Zhang, Xi Ye, Daiyin Peng and Weidong Chen
      Drug Metabolism and Disposition August 2019, 47 (8) 785-793; DOI: https://doi.org/10.1124/dmd.119.086769

  4. Yousif, Mohamed D.

    1. Fexofenadine and Rosuvastatin Pharmacokinetics in Mice with Targeted Disruption of Organic Anion Transporting Polypeptide 2B1
      Samantha Medwid, Mandy M.J. Li, Michael J. Knauer, Kathleen Lin, Sara E. Mansell, Crystal L. Schmerk, Catherine Zhu, Katelyn E. Griffin, Mohamed D. Yousif, George K. Dresser, Ute I. Schwarz, Richard B. Kim and Rommel G. Tirona
      Drug Metabolism and Disposition August 2019, 47 (8) 832-842; DOI: https://doi.org/10.1124/dmd.119.087619

Z

  1. Zamek-Gliszczynski, Maciej J.

    1. Clinical Extrapolation of the Effects of Dolutegravir and Other HIV Integrase Inhibitors on Folate Transport Pathways
      Maciej J. Zamek-Gliszczynski, Xuexiang Zhang, Jennypher Mudunuru, Yewei Du, Jian-Lu Chen, Kunal S. Taskar, Jane Huang, Yong Huang and Elizabeth H. Romach
      Drug Metabolism and Disposition August 2019, 47 (8) 890-898; DOI: https://doi.org/10.1124/dmd.119.087635

  2. Zhang, Donglu

    1. Carfilzomib Is Not an Appropriate Payload of Antibody-Drug Conjugates Due to Rapid Inactivation by Lysosomal Enzymes
      Yong Ma, Josefa Dela Cruz-Chuh, S. Cyrus Khojasteh, Peter S. Dragovich, Thomas H. Pillow and Donglu Zhang
      Drug Metabolism and Disposition August 2019, 47 (8) 884-889; DOI: https://doi.org/10.1124/dmd.119.086595

  3. Zhang, Ling

    1. Activation of Pregnane X Receptor–Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo
      Activation of Pregnane X Receptor–Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo
      Fengling Wang, Huihui Wang, Yifan Wu, Lei Wang, Ling Zhang, Xi Ye, Daiyin Peng and Weidong Chen
      Drug Metabolism and Disposition August 2019, 47 (8) 785-793; DOI: https://doi.org/10.1124/dmd.119.086769

  4. Zhang, Mian

    1. The Regional-Specific Relative and Absolute Expression of Gut Transporters in Adult Caucasians: A Meta-Analysis
      Open Access
      The Regional-Specific Relative and Absolute Expression of Gut Transporters in Adult Caucasians: A Meta-Analysis
      Matthew D. Harwood, Mian Zhang, Shriram M. Pathak and Sibylle Neuhoff
      Drug Metabolism and Disposition August 2019, 47 (8) 854-864; DOI: https://doi.org/10.1124/dmd.119.086959

  5. Zhang, Xuexiang

    1. Clinical Extrapolation of the Effects of Dolutegravir and Other HIV Integrase Inhibitors on Folate Transport Pathways
      Maciej J. Zamek-Gliszczynski, Xuexiang Zhang, Jennypher Mudunuru, Yewei Du, Jian-Lu Chen, Kunal S. Taskar, Jane Huang, Yong Huang and Elizabeth H. Romach
      Drug Metabolism and Disposition August 2019, 47 (8) 890-898; DOI: https://doi.org/10.1124/dmd.119.087635

  6. Zheng, Jiang

    1. Nitidine Chloride–Induced CYP1 Enzyme Inhibition and Alteration of Estradiol Metabolism
      Xu Mao, Jian Wang, Qian Wang, Lan Yang, Yilin Li, Hao Lin, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition August 2019, 47 (8) 919-927; DOI: https://doi.org/10.1124/dmd.119.086892

  7. Zhong, Dafang

    1. Carboxylesterase 2 and Intestine Transporters Contribute to the Low Bioavailability of Allisartan, a Prodrug of Exp3174 for Hypertension Treatment in Humans
      Xiuli Li, Jingchao Sun, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition August 2019, 47 (8) 843-853; DOI: https://doi.org/10.1124/dmd.118.085092

  8. Zhu, Catherine

    1. Fexofenadine and Rosuvastatin Pharmacokinetics in Mice with Targeted Disruption of Organic Anion Transporting Polypeptide 2B1
      Samantha Medwid, Mandy M.J. Li, Michael J. Knauer, Kathleen Lin, Sara E. Mansell, Crystal L. Schmerk, Catherine Zhu, Katelyn E. Griffin, Mohamed D. Yousif, George K. Dresser, Ute I. Schwarz, Richard B. Kim and Rommel G. Tirona
      Drug Metabolism and Disposition August 2019, 47 (8) 832-842; DOI: https://doi.org/10.1124/dmd.119.087619
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