Table of Contents

Articles

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  Plasma Protein and Lipoprotein Binding of Cis- and Trans-Permethrin and Deltamethrin in Adult Humans and Rats

  Pankaj Sethi, James V. Bruckner, Tanzir B. Mortuza, Brian S. Cummings, Srinivasa Muralidhara and Catherine A. White

  Drug Metabolism and Disposition September 2019, 47 (9) 941-948; DOI: https://doi.org/10.1124/dmd.118.085464
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  Interactions between Maraviroc and the ABCB1, ABCG2, and ABCC2 Transporters: An Important Role in Transplacental Pharmacokinetics

  Lenka Tupova, Martina Ceckova, Csilla Ambrus, Ales Sorf, Zuzana Ptackova, Zsuzsanna Gaborik and Frantisek Staud

  Drug Metabolism and Disposition September 2019, 47 (9) 954-960; DOI: https://doi.org/10.1124/dmd.119.087684
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  Arylacetamide Deacetylase Enzyme: Presence and Interindividual Variability in Human Lungs

  Morena Gabriele, Paola Puccini, Marco Lucchi, Vittorio Aprile, Pier Giovanni Gervasi and Vincenzo Longo

  Drug Metabolism and Disposition September 2019, 47 (9) 961-965; DOI: https://doi.org/10.1124/dmd.119.087031
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  GDC-0810 Pharmacokinetics and Transporter-Mediated Drug Interaction Evaluation with an Endogenous Biomarker in the First-in-Human, Dose Escalation Study

  Kit Wun Kathy Cheung, Kenta Yoshida, Sravanthi Cheeti, Buyun Chen, Roland Morley, Iris T. Chan, Srikumar Sahasranaman and Lichuan Liu

  Drug Metabolism and Disposition September 2019, 47 (9) 966-973; DOI: https://doi.org/10.1124/dmd.119.087924
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  Specificity of the Redox Complex between Cytochrome P450 24A1 and Adrenodoxin Relies on Carbon-25 Hydroxylation of Vitamin-D Substrate

  Amit Kumar and D. Fernando Estrada

  Drug Metabolism and Disposition September 2019, 47 (9) 974-982; DOI: https://doi.org/10.1124/dmd.119.087759
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  Single Nucleotide Polymorphisms at a Distance from Aryl Hydrocarbon Receptor (AHR) Binding Sites Influence AHR Ligand–Dependent Gene Expression

  Drew R. Neavin, Jeong-Heon Lee, Duan Liu, Zhenqing Ye, Hu Li, Liewei Wang, Tamas Ordog and Richard M. Weinshilboum

  Drug Metabolism and Disposition September 2019, 47 (9) 983-994; DOI: https://doi.org/10.1124/dmd.119.087312
• Open Access

  Structure-Guided In Vitro to In Vivo Pharmacokinetic Optimization of Propargyl-Linked Antifolates

  M.N. Lombardo, N. G-Dayanandan, S. Keshipeddy, W. Zhou, D. Si, S.M. Reeve, J. Alverson, P. Barney, L. Walker, J. Hoody, N.D. Priestley, R.S. Obach and D.L. Wright

  Drug Metabolism and Disposition September 2019, 47 (9) 995-1003; DOI: https://doi.org/10.1124/dmd.119.086504
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  The Enhancement of Subcutaneous First-Pass Metabolism Causes Nonlinear Pharmacokinetics of TAK-448 after a Single Subcutaneous Administration to Rats

  Yuu Moriya, Akifumi Kogame, Yoshihiko Tagawa, Akio Morohashi, Takahiro Kondo, Satoru Asahi and Leslie Z. Benet

  Drug Metabolism and Disposition September 2019, 47 (9) 1004-1012; DOI: https://doi.org/10.1124/dmd.119.087148