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Drug Metabolism & Disposition

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    • Current Issue
    • Fast Forward
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Index by author

September 01, 2019; Volume 47,Issue 9
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Alverson, J.

    1. Open Access
      Structure-Guided In Vitro to In Vivo Pharmacokinetic Optimization of Propargyl-Linked Antifolates
      M.N. Lombardo, N. G-Dayanandan, S. Keshipeddy, W. Zhou, D. Si, S.M. Reeve, J. Alverson, P. Barney, L. Walker, J. Hoody, N.D. Priestley, R.S. Obach and D.L. Wright
      Drug Metabolism and Disposition September 2019, 47 (9) 995-1003; DOI: https://doi.org/10.1124/dmd.119.086504
  2. Ambrus, Csilla

    1. You have access
      Interactions between Maraviroc and the ABCB1, ABCG2, and ABCC2 Transporters: An Important Role in Transplacental Pharmacokinetics
      Lenka Tupova, Martina Ceckova, Csilla Ambrus, Ales Sorf, Zuzana Ptackova, Zsuzsanna Gaborik and Frantisek Staud
      Drug Metabolism and Disposition September 2019, 47 (9) 954-960; DOI: https://doi.org/10.1124/dmd.119.087684
  3. Andrabi, Shaida A.

    1. You have access
      SULT4A1 Protects Against Oxidative-Stress Induced Mitochondrial Dysfunction in Neuronal Cells
      Mohammed I. Hossain, Joshua M. Marcus, Jun Hee Lee, Patrick L. Garcia, Jean-Philippe Gagné, Guy G. Poirier, Charles N. Falany and Shaida A. Andrabi
      Drug Metabolism and Disposition September 2019, 47 (9) 949-953; DOI: https://doi.org/10.1124/dmd.119.088047
  4. Aprile, Vittorio

    1. Arylacetamide Deacetylase Enzyme: Presence and Interindividual Variability in Human Lungs
      You have access
      Arylacetamide Deacetylase Enzyme: Presence and Interindividual Variability in Human Lungs
      Morena Gabriele, Paola Puccini, Marco Lucchi, Vittorio Aprile, Pier Giovanni Gervasi and Vincenzo Longo
      Drug Metabolism and Disposition September 2019, 47 (9) 961-965; DOI: https://doi.org/10.1124/dmd.119.087031
  5. Asahi, Satoru

    1. You have access
      The Enhancement of Subcutaneous First-Pass Metabolism Causes Nonlinear Pharmacokinetics of TAK-448 after a Single Subcutaneous Administration to Rats
      Yuu Moriya, Akifumi Kogame, Yoshihiko Tagawa, Akio Morohashi, Takahiro Kondo, Satoru Asahi and Leslie Z. Benet
      Drug Metabolism and Disposition September 2019, 47 (9) 1004-1012; DOI: https://doi.org/10.1124/dmd.119.087148

B

  1. Barney, P.

    1. Open Access
      Structure-Guided In Vitro to In Vivo Pharmacokinetic Optimization of Propargyl-Linked Antifolates
      M.N. Lombardo, N. G-Dayanandan, S. Keshipeddy, W. Zhou, D. Si, S.M. Reeve, J. Alverson, P. Barney, L. Walker, J. Hoody, N.D. Priestley, R.S. Obach and D.L. Wright
      Drug Metabolism and Disposition September 2019, 47 (9) 995-1003; DOI: https://doi.org/10.1124/dmd.119.086504
  2. Benet, Leslie Z.

    1. You have access
      The Enhancement of Subcutaneous First-Pass Metabolism Causes Nonlinear Pharmacokinetics of TAK-448 after a Single Subcutaneous Administration to Rats
      Yuu Moriya, Akifumi Kogame, Yoshihiko Tagawa, Akio Morohashi, Takahiro Kondo, Satoru Asahi and Leslie Z. Benet
      Drug Metabolism and Disposition September 2019, 47 (9) 1004-1012; DOI: https://doi.org/10.1124/dmd.119.087148
  3. Bruckner, James V.

    1. You have access
      Plasma Protein and Lipoprotein Binding of Cis- and Trans-Permethrin and Deltamethrin in Adult Humans and Rats
      Pankaj Sethi, James V. Bruckner, Tanzir B. Mortuza, Brian S. Cummings, Srinivasa Muralidhara and Catherine A. White
      Drug Metabolism and Disposition September 2019, 47 (9) 941-948; DOI: https://doi.org/10.1124/dmd.118.085464

C

  1. Ceckova, Martina

    1. You have access
      Interactions between Maraviroc and the ABCB1, ABCG2, and ABCC2 Transporters: An Important Role in Transplacental Pharmacokinetics
      Lenka Tupova, Martina Ceckova, Csilla Ambrus, Ales Sorf, Zuzana Ptackova, Zsuzsanna Gaborik and Frantisek Staud
      Drug Metabolism and Disposition September 2019, 47 (9) 954-960; DOI: https://doi.org/10.1124/dmd.119.087684
  2. Chan, Iris T.

    1. You have access
      GDC-0810 Pharmacokinetics and Transporter-Mediated Drug Interaction Evaluation with an Endogenous Biomarker in the First-in-Human, Dose Escalation Study
      Kit Wun Kathy Cheung, Kenta Yoshida, Sravanthi Cheeti, Buyun Chen, Roland Morley, Iris T. Chan, Srikumar Sahasranaman and Lichuan Liu
      Drug Metabolism and Disposition September 2019, 47 (9) 966-973; DOI: https://doi.org/10.1124/dmd.119.087924
  3. Cheeti, Sravanthi

    1. You have access
      GDC-0810 Pharmacokinetics and Transporter-Mediated Drug Interaction Evaluation with an Endogenous Biomarker in the First-in-Human, Dose Escalation Study
      Kit Wun Kathy Cheung, Kenta Yoshida, Sravanthi Cheeti, Buyun Chen, Roland Morley, Iris T. Chan, Srikumar Sahasranaman and Lichuan Liu
      Drug Metabolism and Disposition September 2019, 47 (9) 966-973; DOI: https://doi.org/10.1124/dmd.119.087924
  4. Chen, Buyun

    1. You have access
      GDC-0810 Pharmacokinetics and Transporter-Mediated Drug Interaction Evaluation with an Endogenous Biomarker in the First-in-Human, Dose Escalation Study
      Kit Wun Kathy Cheung, Kenta Yoshida, Sravanthi Cheeti, Buyun Chen, Roland Morley, Iris T. Chan, Srikumar Sahasranaman and Lichuan Liu
      Drug Metabolism and Disposition September 2019, 47 (9) 966-973; DOI: https://doi.org/10.1124/dmd.119.087924
  5. Cheung, Kit Wun Kathy

    1. You have access
      GDC-0810 Pharmacokinetics and Transporter-Mediated Drug Interaction Evaluation with an Endogenous Biomarker in the First-in-Human, Dose Escalation Study
      Kit Wun Kathy Cheung, Kenta Yoshida, Sravanthi Cheeti, Buyun Chen, Roland Morley, Iris T. Chan, Srikumar Sahasranaman and Lichuan Liu
      Drug Metabolism and Disposition September 2019, 47 (9) 966-973; DOI: https://doi.org/10.1124/dmd.119.087924
  6. Cummings, Brian S.

    1. You have access
      Plasma Protein and Lipoprotein Binding of Cis- and Trans-Permethrin and Deltamethrin in Adult Humans and Rats
      Pankaj Sethi, James V. Bruckner, Tanzir B. Mortuza, Brian S. Cummings, Srinivasa Muralidhara and Catherine A. White
      Drug Metabolism and Disposition September 2019, 47 (9) 941-948; DOI: https://doi.org/10.1124/dmd.118.085464

E

  1. Estrada, D. Fernando

    1. Specificity of the Redox Complex between Cytochrome P450 24A1 and Adrenodoxin Relies on Carbon-25 Hydroxylation of Vitamin-D Substrate
      You have access
      Specificity of the Redox Complex between Cytochrome P450 24A1 and Adrenodoxin Relies on Carbon-25 Hydroxylation of Vitamin-D Substrate
      Amit Kumar and D. Fernando Estrada
      Drug Metabolism and Disposition September 2019, 47 (9) 974-982; DOI: https://doi.org/10.1124/dmd.119.087759

F

  1. Falany, Charles N.

    1. You have access
      SULT4A1 Protects Against Oxidative-Stress Induced Mitochondrial Dysfunction in Neuronal Cells
      Mohammed I. Hossain, Joshua M. Marcus, Jun Hee Lee, Patrick L. Garcia, Jean-Philippe Gagné, Guy G. Poirier, Charles N. Falany and Shaida A. Andrabi
      Drug Metabolism and Disposition September 2019, 47 (9) 949-953; DOI: https://doi.org/10.1124/dmd.119.088047

G

  1. G-Dayanandan, N.

    1. Open Access
      Structure-Guided In Vitro to In Vivo Pharmacokinetic Optimization of Propargyl-Linked Antifolates
      M.N. Lombardo, N. G-Dayanandan, S. Keshipeddy, W. Zhou, D. Si, S.M. Reeve, J. Alverson, P. Barney, L. Walker, J. Hoody, N.D. Priestley, R.S. Obach and D.L. Wright
      Drug Metabolism and Disposition September 2019, 47 (9) 995-1003; DOI: https://doi.org/10.1124/dmd.119.086504
  2. Gaborik, Zsuzsanna

    1. You have access
      Interactions between Maraviroc and the ABCB1, ABCG2, and ABCC2 Transporters: An Important Role in Transplacental Pharmacokinetics
      Lenka Tupova, Martina Ceckova, Csilla Ambrus, Ales Sorf, Zuzana Ptackova, Zsuzsanna Gaborik and Frantisek Staud
      Drug Metabolism and Disposition September 2019, 47 (9) 954-960; DOI: https://doi.org/10.1124/dmd.119.087684
  3. Gabriele, Morena

    1. Arylacetamide Deacetylase Enzyme: Presence and Interindividual Variability in Human Lungs
      You have access
      Arylacetamide Deacetylase Enzyme: Presence and Interindividual Variability in Human Lungs
      Morena Gabriele, Paola Puccini, Marco Lucchi, Vittorio Aprile, Pier Giovanni Gervasi and Vincenzo Longo
      Drug Metabolism and Disposition September 2019, 47 (9) 961-965; DOI: https://doi.org/10.1124/dmd.119.087031
  4. Gagné, Jean-Philippe

    1. You have access
      SULT4A1 Protects Against Oxidative-Stress Induced Mitochondrial Dysfunction in Neuronal Cells
      Mohammed I. Hossain, Joshua M. Marcus, Jun Hee Lee, Patrick L. Garcia, Jean-Philippe Gagné, Guy G. Poirier, Charles N. Falany and Shaida A. Andrabi
      Drug Metabolism and Disposition September 2019, 47 (9) 949-953; DOI: https://doi.org/10.1124/dmd.119.088047
  5. Garcia, Patrick L.

    1. You have access
      SULT4A1 Protects Against Oxidative-Stress Induced Mitochondrial Dysfunction in Neuronal Cells
      Mohammed I. Hossain, Joshua M. Marcus, Jun Hee Lee, Patrick L. Garcia, Jean-Philippe Gagné, Guy G. Poirier, Charles N. Falany and Shaida A. Andrabi
      Drug Metabolism and Disposition September 2019, 47 (9) 949-953; DOI: https://doi.org/10.1124/dmd.119.088047
  6. Gervasi, Pier Giovanni

    1. Arylacetamide Deacetylase Enzyme: Presence and Interindividual Variability in Human Lungs
      You have access
      Arylacetamide Deacetylase Enzyme: Presence and Interindividual Variability in Human Lungs
      Morena Gabriele, Paola Puccini, Marco Lucchi, Vittorio Aprile, Pier Giovanni Gervasi and Vincenzo Longo
      Drug Metabolism and Disposition September 2019, 47 (9) 961-965; DOI: https://doi.org/10.1124/dmd.119.087031

H

  1. Hoody, J.

    1. Open Access
      Structure-Guided In Vitro to In Vivo Pharmacokinetic Optimization of Propargyl-Linked Antifolates
      M.N. Lombardo, N. G-Dayanandan, S. Keshipeddy, W. Zhou, D. Si, S.M. Reeve, J. Alverson, P. Barney, L. Walker, J. Hoody, N.D. Priestley, R.S. Obach and D.L. Wright
      Drug Metabolism and Disposition September 2019, 47 (9) 995-1003; DOI: https://doi.org/10.1124/dmd.119.086504
  2. Hossain, Mohammed I.

    1. You have access
      SULT4A1 Protects Against Oxidative-Stress Induced Mitochondrial Dysfunction in Neuronal Cells
      Mohammed I. Hossain, Joshua M. Marcus, Jun Hee Lee, Patrick L. Garcia, Jean-Philippe Gagné, Guy G. Poirier, Charles N. Falany and Shaida A. Andrabi
      Drug Metabolism and Disposition September 2019, 47 (9) 949-953; DOI: https://doi.org/10.1124/dmd.119.088047

K

  1. Keshipeddy, S.

    1. Open Access
      Structure-Guided In Vitro to In Vivo Pharmacokinetic Optimization of Propargyl-Linked Antifolates
      M.N. Lombardo, N. G-Dayanandan, S. Keshipeddy, W. Zhou, D. Si, S.M. Reeve, J. Alverson, P. Barney, L. Walker, J. Hoody, N.D. Priestley, R.S. Obach and D.L. Wright
      Drug Metabolism and Disposition September 2019, 47 (9) 995-1003; DOI: https://doi.org/10.1124/dmd.119.086504
  2. Kogame, Akifumi

    1. You have access
      The Enhancement of Subcutaneous First-Pass Metabolism Causes Nonlinear Pharmacokinetics of TAK-448 after a Single Subcutaneous Administration to Rats
      Yuu Moriya, Akifumi Kogame, Yoshihiko Tagawa, Akio Morohashi, Takahiro Kondo, Satoru Asahi and Leslie Z. Benet
      Drug Metabolism and Disposition September 2019, 47 (9) 1004-1012; DOI: https://doi.org/10.1124/dmd.119.087148
  3. Kondo, Takahiro

    1. You have access
      The Enhancement of Subcutaneous First-Pass Metabolism Causes Nonlinear Pharmacokinetics of TAK-448 after a Single Subcutaneous Administration to Rats
      Yuu Moriya, Akifumi Kogame, Yoshihiko Tagawa, Akio Morohashi, Takahiro Kondo, Satoru Asahi and Leslie Z. Benet
      Drug Metabolism and Disposition September 2019, 47 (9) 1004-1012; DOI: https://doi.org/10.1124/dmd.119.087148
  4. Kumar, Amit

    1. Specificity of the Redox Complex between Cytochrome P450 24A1 and Adrenodoxin Relies on Carbon-25 Hydroxylation of Vitamin-D Substrate
      You have access
      Specificity of the Redox Complex between Cytochrome P450 24A1 and Adrenodoxin Relies on Carbon-25 Hydroxylation of Vitamin-D Substrate
      Amit Kumar and D. Fernando Estrada
      Drug Metabolism and Disposition September 2019, 47 (9) 974-982; DOI: https://doi.org/10.1124/dmd.119.087759

L

  1. Lee, Jeong-Heon

    1. Open Access
      Single Nucleotide Polymorphisms at a Distance from Aryl Hydrocarbon Receptor (AHR) Binding Sites Influence AHR Ligand–Dependent Gene Expression
      Drew R. Neavin, Jeong-Heon Lee, Duan Liu, Zhenqing Ye, Hu Li, Liewei Wang, Tamas Ordog and Richard M. Weinshilboum
      Drug Metabolism and Disposition September 2019, 47 (9) 983-994; DOI: https://doi.org/10.1124/dmd.119.087312
  2. Lee, Jun Hee

    1. You have access
      SULT4A1 Protects Against Oxidative-Stress Induced Mitochondrial Dysfunction in Neuronal Cells
      Mohammed I. Hossain, Joshua M. Marcus, Jun Hee Lee, Patrick L. Garcia, Jean-Philippe Gagné, Guy G. Poirier, Charles N. Falany and Shaida A. Andrabi
      Drug Metabolism and Disposition September 2019, 47 (9) 949-953; DOI: https://doi.org/10.1124/dmd.119.088047
  3. Li, Hu

    1. Open Access
      Single Nucleotide Polymorphisms at a Distance from Aryl Hydrocarbon Receptor (AHR) Binding Sites Influence AHR Ligand–Dependent Gene Expression
      Drew R. Neavin, Jeong-Heon Lee, Duan Liu, Zhenqing Ye, Hu Li, Liewei Wang, Tamas Ordog and Richard M. Weinshilboum
      Drug Metabolism and Disposition September 2019, 47 (9) 983-994; DOI: https://doi.org/10.1124/dmd.119.087312
  4. Liu, Duan

    1. Open Access
      Single Nucleotide Polymorphisms at a Distance from Aryl Hydrocarbon Receptor (AHR) Binding Sites Influence AHR Ligand–Dependent Gene Expression
      Drew R. Neavin, Jeong-Heon Lee, Duan Liu, Zhenqing Ye, Hu Li, Liewei Wang, Tamas Ordog and Richard M. Weinshilboum
      Drug Metabolism and Disposition September 2019, 47 (9) 983-994; DOI: https://doi.org/10.1124/dmd.119.087312
  5. Liu, Lichuan

    1. You have access
      GDC-0810 Pharmacokinetics and Transporter-Mediated Drug Interaction Evaluation with an Endogenous Biomarker in the First-in-Human, Dose Escalation Study
      Kit Wun Kathy Cheung, Kenta Yoshida, Sravanthi Cheeti, Buyun Chen, Roland Morley, Iris T. Chan, Srikumar Sahasranaman and Lichuan Liu
      Drug Metabolism and Disposition September 2019, 47 (9) 966-973; DOI: https://doi.org/10.1124/dmd.119.087924
  6. Lombardo, M.N.

    1. Open Access
      Structure-Guided In Vitro to In Vivo Pharmacokinetic Optimization of Propargyl-Linked Antifolates
      M.N. Lombardo, N. G-Dayanandan, S. Keshipeddy, W. Zhou, D. Si, S.M. Reeve, J. Alverson, P. Barney, L. Walker, J. Hoody, N.D. Priestley, R.S. Obach and D.L. Wright
      Drug Metabolism and Disposition September 2019, 47 (9) 995-1003; DOI: https://doi.org/10.1124/dmd.119.086504
  7. Longo, Vincenzo

    1. Arylacetamide Deacetylase Enzyme: Presence and Interindividual Variability in Human Lungs
      You have access
      Arylacetamide Deacetylase Enzyme: Presence and Interindividual Variability in Human Lungs
      Morena Gabriele, Paola Puccini, Marco Lucchi, Vittorio Aprile, Pier Giovanni Gervasi and Vincenzo Longo
      Drug Metabolism and Disposition September 2019, 47 (9) 961-965; DOI: https://doi.org/10.1124/dmd.119.087031
  8. Lucchi, Marco

    1. Arylacetamide Deacetylase Enzyme: Presence and Interindividual Variability in Human Lungs
      You have access
      Arylacetamide Deacetylase Enzyme: Presence and Interindividual Variability in Human Lungs
      Morena Gabriele, Paola Puccini, Marco Lucchi, Vittorio Aprile, Pier Giovanni Gervasi and Vincenzo Longo
      Drug Metabolism and Disposition September 2019, 47 (9) 961-965; DOI: https://doi.org/10.1124/dmd.119.087031

M

  1. Marcus, Joshua M.

    1. You have access
      SULT4A1 Protects Against Oxidative-Stress Induced Mitochondrial Dysfunction in Neuronal Cells
      Mohammed I. Hossain, Joshua M. Marcus, Jun Hee Lee, Patrick L. Garcia, Jean-Philippe Gagné, Guy G. Poirier, Charles N. Falany and Shaida A. Andrabi
      Drug Metabolism and Disposition September 2019, 47 (9) 949-953; DOI: https://doi.org/10.1124/dmd.119.088047
  2. Moriya, Yuu

    1. You have access
      The Enhancement of Subcutaneous First-Pass Metabolism Causes Nonlinear Pharmacokinetics of TAK-448 after a Single Subcutaneous Administration to Rats
      Yuu Moriya, Akifumi Kogame, Yoshihiko Tagawa, Akio Morohashi, Takahiro Kondo, Satoru Asahi and Leslie Z. Benet
      Drug Metabolism and Disposition September 2019, 47 (9) 1004-1012; DOI: https://doi.org/10.1124/dmd.119.087148
  3. Morley, Roland

    1. You have access
      GDC-0810 Pharmacokinetics and Transporter-Mediated Drug Interaction Evaluation with an Endogenous Biomarker in the First-in-Human, Dose Escalation Study
      Kit Wun Kathy Cheung, Kenta Yoshida, Sravanthi Cheeti, Buyun Chen, Roland Morley, Iris T. Chan, Srikumar Sahasranaman and Lichuan Liu
      Drug Metabolism and Disposition September 2019, 47 (9) 966-973; DOI: https://doi.org/10.1124/dmd.119.087924
  4. Morohashi, Akio

    1. You have access
      The Enhancement of Subcutaneous First-Pass Metabolism Causes Nonlinear Pharmacokinetics of TAK-448 after a Single Subcutaneous Administration to Rats
      Yuu Moriya, Akifumi Kogame, Yoshihiko Tagawa, Akio Morohashi, Takahiro Kondo, Satoru Asahi and Leslie Z. Benet
      Drug Metabolism and Disposition September 2019, 47 (9) 1004-1012; DOI: https://doi.org/10.1124/dmd.119.087148
  5. Mortuza, Tanzir B.

    1. You have access
      Plasma Protein and Lipoprotein Binding of Cis- and Trans-Permethrin and Deltamethrin in Adult Humans and Rats
      Pankaj Sethi, James V. Bruckner, Tanzir B. Mortuza, Brian S. Cummings, Srinivasa Muralidhara and Catherine A. White
      Drug Metabolism and Disposition September 2019, 47 (9) 941-948; DOI: https://doi.org/10.1124/dmd.118.085464
  6. Muralidhara, Srinivasa

    1. You have access
      Plasma Protein and Lipoprotein Binding of Cis- and Trans-Permethrin and Deltamethrin in Adult Humans and Rats
      Pankaj Sethi, James V. Bruckner, Tanzir B. Mortuza, Brian S. Cummings, Srinivasa Muralidhara and Catherine A. White
      Drug Metabolism and Disposition September 2019, 47 (9) 941-948; DOI: https://doi.org/10.1124/dmd.118.085464

N

  1. Neavin, Drew R.

    1. Open Access
      Single Nucleotide Polymorphisms at a Distance from Aryl Hydrocarbon Receptor (AHR) Binding Sites Influence AHR Ligand–Dependent Gene Expression
      Drew R. Neavin, Jeong-Heon Lee, Duan Liu, Zhenqing Ye, Hu Li, Liewei Wang, Tamas Ordog and Richard M. Weinshilboum
      Drug Metabolism and Disposition September 2019, 47 (9) 983-994; DOI: https://doi.org/10.1124/dmd.119.087312

O

  1. Obach, R.S.

    1. Open Access
      Structure-Guided In Vitro to In Vivo Pharmacokinetic Optimization of Propargyl-Linked Antifolates
      M.N. Lombardo, N. G-Dayanandan, S. Keshipeddy, W. Zhou, D. Si, S.M. Reeve, J. Alverson, P. Barney, L. Walker, J. Hoody, N.D. Priestley, R.S. Obach and D.L. Wright
      Drug Metabolism and Disposition September 2019, 47 (9) 995-1003; DOI: https://doi.org/10.1124/dmd.119.086504
  2. Ordog, Tamas

    1. Open Access
      Single Nucleotide Polymorphisms at a Distance from Aryl Hydrocarbon Receptor (AHR) Binding Sites Influence AHR Ligand–Dependent Gene Expression
      Drew R. Neavin, Jeong-Heon Lee, Duan Liu, Zhenqing Ye, Hu Li, Liewei Wang, Tamas Ordog and Richard M. Weinshilboum
      Drug Metabolism and Disposition September 2019, 47 (9) 983-994; DOI: https://doi.org/10.1124/dmd.119.087312

P

  1. Poirier, Guy G.

    1. You have access
      SULT4A1 Protects Against Oxidative-Stress Induced Mitochondrial Dysfunction in Neuronal Cells
      Mohammed I. Hossain, Joshua M. Marcus, Jun Hee Lee, Patrick L. Garcia, Jean-Philippe Gagné, Guy G. Poirier, Charles N. Falany and Shaida A. Andrabi
      Drug Metabolism and Disposition September 2019, 47 (9) 949-953; DOI: https://doi.org/10.1124/dmd.119.088047
  2. Priestley, N.D.

    1. Open Access
      Structure-Guided In Vitro to In Vivo Pharmacokinetic Optimization of Propargyl-Linked Antifolates
      M.N. Lombardo, N. G-Dayanandan, S. Keshipeddy, W. Zhou, D. Si, S.M. Reeve, J. Alverson, P. Barney, L. Walker, J. Hoody, N.D. Priestley, R.S. Obach and D.L. Wright
      Drug Metabolism and Disposition September 2019, 47 (9) 995-1003; DOI: https://doi.org/10.1124/dmd.119.086504
  3. Ptackova, Zuzana

    1. You have access
      Interactions between Maraviroc and the ABCB1, ABCG2, and ABCC2 Transporters: An Important Role in Transplacental Pharmacokinetics
      Lenka Tupova, Martina Ceckova, Csilla Ambrus, Ales Sorf, Zuzana Ptackova, Zsuzsanna Gaborik and Frantisek Staud
      Drug Metabolism and Disposition September 2019, 47 (9) 954-960; DOI: https://doi.org/10.1124/dmd.119.087684
  4. Puccini, Paola

    1. Arylacetamide Deacetylase Enzyme: Presence and Interindividual Variability in Human Lungs
      You have access
      Arylacetamide Deacetylase Enzyme: Presence and Interindividual Variability in Human Lungs
      Morena Gabriele, Paola Puccini, Marco Lucchi, Vittorio Aprile, Pier Giovanni Gervasi and Vincenzo Longo
      Drug Metabolism and Disposition September 2019, 47 (9) 961-965; DOI: https://doi.org/10.1124/dmd.119.087031

R

  1. Reeve, S.M.

    1. Open Access
      Structure-Guided In Vitro to In Vivo Pharmacokinetic Optimization of Propargyl-Linked Antifolates
      M.N. Lombardo, N. G-Dayanandan, S. Keshipeddy, W. Zhou, D. Si, S.M. Reeve, J. Alverson, P. Barney, L. Walker, J. Hoody, N.D. Priestley, R.S. Obach and D.L. Wright
      Drug Metabolism and Disposition September 2019, 47 (9) 995-1003; DOI: https://doi.org/10.1124/dmd.119.086504

S

  1. Sahasranaman, Srikumar

    1. You have access
      GDC-0810 Pharmacokinetics and Transporter-Mediated Drug Interaction Evaluation with an Endogenous Biomarker in the First-in-Human, Dose Escalation Study
      Kit Wun Kathy Cheung, Kenta Yoshida, Sravanthi Cheeti, Buyun Chen, Roland Morley, Iris T. Chan, Srikumar Sahasranaman and Lichuan Liu
      Drug Metabolism and Disposition September 2019, 47 (9) 966-973; DOI: https://doi.org/10.1124/dmd.119.087924
  2. Sethi, Pankaj

    1. You have access
      Plasma Protein and Lipoprotein Binding of Cis- and Trans-Permethrin and Deltamethrin in Adult Humans and Rats
      Pankaj Sethi, James V. Bruckner, Tanzir B. Mortuza, Brian S. Cummings, Srinivasa Muralidhara and Catherine A. White
      Drug Metabolism and Disposition September 2019, 47 (9) 941-948; DOI: https://doi.org/10.1124/dmd.118.085464
  3. Si, D.

    1. Open Access
      Structure-Guided In Vitro to In Vivo Pharmacokinetic Optimization of Propargyl-Linked Antifolates
      M.N. Lombardo, N. G-Dayanandan, S. Keshipeddy, W. Zhou, D. Si, S.M. Reeve, J. Alverson, P. Barney, L. Walker, J. Hoody, N.D. Priestley, R.S. Obach and D.L. Wright
      Drug Metabolism and Disposition September 2019, 47 (9) 995-1003; DOI: https://doi.org/10.1124/dmd.119.086504
  4. Sorf, Ales

    1. You have access
      Interactions between Maraviroc and the ABCB1, ABCG2, and ABCC2 Transporters: An Important Role in Transplacental Pharmacokinetics
      Lenka Tupova, Martina Ceckova, Csilla Ambrus, Ales Sorf, Zuzana Ptackova, Zsuzsanna Gaborik and Frantisek Staud
      Drug Metabolism and Disposition September 2019, 47 (9) 954-960; DOI: https://doi.org/10.1124/dmd.119.087684
  5. Staud, Frantisek

    1. You have access
      Interactions between Maraviroc and the ABCB1, ABCG2, and ABCC2 Transporters: An Important Role in Transplacental Pharmacokinetics
      Lenka Tupova, Martina Ceckova, Csilla Ambrus, Ales Sorf, Zuzana Ptackova, Zsuzsanna Gaborik and Frantisek Staud
      Drug Metabolism and Disposition September 2019, 47 (9) 954-960; DOI: https://doi.org/10.1124/dmd.119.087684

T

  1. Tagawa, Yoshihiko

    1. You have access
      The Enhancement of Subcutaneous First-Pass Metabolism Causes Nonlinear Pharmacokinetics of TAK-448 after a Single Subcutaneous Administration to Rats
      Yuu Moriya, Akifumi Kogame, Yoshihiko Tagawa, Akio Morohashi, Takahiro Kondo, Satoru Asahi and Leslie Z. Benet
      Drug Metabolism and Disposition September 2019, 47 (9) 1004-1012; DOI: https://doi.org/10.1124/dmd.119.087148
  2. Tupova, Lenka

    1. You have access
      Interactions between Maraviroc and the ABCB1, ABCG2, and ABCC2 Transporters: An Important Role in Transplacental Pharmacokinetics
      Lenka Tupova, Martina Ceckova, Csilla Ambrus, Ales Sorf, Zuzana Ptackova, Zsuzsanna Gaborik and Frantisek Staud
      Drug Metabolism and Disposition September 2019, 47 (9) 954-960; DOI: https://doi.org/10.1124/dmd.119.087684

W

  1. Walker, L.

    1. Open Access
      Structure-Guided In Vitro to In Vivo Pharmacokinetic Optimization of Propargyl-Linked Antifolates
      M.N. Lombardo, N. G-Dayanandan, S. Keshipeddy, W. Zhou, D. Si, S.M. Reeve, J. Alverson, P. Barney, L. Walker, J. Hoody, N.D. Priestley, R.S. Obach and D.L. Wright
      Drug Metabolism and Disposition September 2019, 47 (9) 995-1003; DOI: https://doi.org/10.1124/dmd.119.086504
  2. Wang, Liewei

    1. Open Access
      Single Nucleotide Polymorphisms at a Distance from Aryl Hydrocarbon Receptor (AHR) Binding Sites Influence AHR Ligand–Dependent Gene Expression
      Drew R. Neavin, Jeong-Heon Lee, Duan Liu, Zhenqing Ye, Hu Li, Liewei Wang, Tamas Ordog and Richard M. Weinshilboum
      Drug Metabolism and Disposition September 2019, 47 (9) 983-994; DOI: https://doi.org/10.1124/dmd.119.087312
  3. Weinshilboum, Richard M.

    1. Open Access
      Single Nucleotide Polymorphisms at a Distance from Aryl Hydrocarbon Receptor (AHR) Binding Sites Influence AHR Ligand–Dependent Gene Expression
      Drew R. Neavin, Jeong-Heon Lee, Duan Liu, Zhenqing Ye, Hu Li, Liewei Wang, Tamas Ordog and Richard M. Weinshilboum
      Drug Metabolism and Disposition September 2019, 47 (9) 983-994; DOI: https://doi.org/10.1124/dmd.119.087312
  4. White, Catherine A.

    1. You have access
      Plasma Protein and Lipoprotein Binding of Cis- and Trans-Permethrin and Deltamethrin in Adult Humans and Rats
      Pankaj Sethi, James V. Bruckner, Tanzir B. Mortuza, Brian S. Cummings, Srinivasa Muralidhara and Catherine A. White
      Drug Metabolism and Disposition September 2019, 47 (9) 941-948; DOI: https://doi.org/10.1124/dmd.118.085464
  5. Wright, D.L.

    1. Open Access
      Structure-Guided In Vitro to In Vivo Pharmacokinetic Optimization of Propargyl-Linked Antifolates
      M.N. Lombardo, N. G-Dayanandan, S. Keshipeddy, W. Zhou, D. Si, S.M. Reeve, J. Alverson, P. Barney, L. Walker, J. Hoody, N.D. Priestley, R.S. Obach and D.L. Wright
      Drug Metabolism and Disposition September 2019, 47 (9) 995-1003; DOI: https://doi.org/10.1124/dmd.119.086504

Y

  1. Ye, Zhenqing

    1. Open Access
      Single Nucleotide Polymorphisms at a Distance from Aryl Hydrocarbon Receptor (AHR) Binding Sites Influence AHR Ligand–Dependent Gene Expression
      Drew R. Neavin, Jeong-Heon Lee, Duan Liu, Zhenqing Ye, Hu Li, Liewei Wang, Tamas Ordog and Richard M. Weinshilboum
      Drug Metabolism and Disposition September 2019, 47 (9) 983-994; DOI: https://doi.org/10.1124/dmd.119.087312
  2. Yoshida, Kenta

    1. You have access
      GDC-0810 Pharmacokinetics and Transporter-Mediated Drug Interaction Evaluation with an Endogenous Biomarker in the First-in-Human, Dose Escalation Study
      Kit Wun Kathy Cheung, Kenta Yoshida, Sravanthi Cheeti, Buyun Chen, Roland Morley, Iris T. Chan, Srikumar Sahasranaman and Lichuan Liu
      Drug Metabolism and Disposition September 2019, 47 (9) 966-973; DOI: https://doi.org/10.1124/dmd.119.087924

Z

  1. Zhou, W.

    1. Open Access
      Structure-Guided In Vitro to In Vivo Pharmacokinetic Optimization of Propargyl-Linked Antifolates
      M.N. Lombardo, N. G-Dayanandan, S. Keshipeddy, W. Zhou, D. Si, S.M. Reeve, J. Alverson, P. Barney, L. Walker, J. Hoody, N.D. Priestley, R.S. Obach and D.L. Wright
      Drug Metabolism and Disposition September 2019, 47 (9) 995-1003; DOI: https://doi.org/10.1124/dmd.119.086504
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Drug Metabolism and Disposition: 47 (9)
Drug Metabolism and Disposition
Vol. 47, Issue 9
1 Sep 2019
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
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