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Drug Metabolism & Disposition

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  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
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Index by author

October 01, 2020; Volume 48,Issue 10
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Alam, Novera

    1. You have access
      Application of Cryopreserved Human Intestinal Mucosa and Cryopreserved Human Enterocytes in the Evaluation of Herb-Drug Interactions: Evaluation of CYP3A Inhibitory Potential of Grapefruit Juice and Commercial Formulations of Twenty-Nine Herbal Supplements
      Carol Loretz, Ming-Chih David Ho, Novera Alam, Walter Mitchell and Albert P. Li
      Drug Metabolism and Disposition October 2020, 48 (10) 1084-1091; DOI: https://doi.org/10.1124/dmd.120.000033
  2. Alilio, Marijanel

    1. Open Access
      A New Data Repository for Pharmacokinetic Natural Product-Drug Interactions: From Chemical Characterization to Clinical Studies
      Caroline Birer-Williams, Brandon T. Gufford, Eric Chou, Marijanel Alilio, Sidney VanAlstine, Rachael E. Morley, Jeannine S. McCune, Mary F. Paine and Richard D. Boyce
      Drug Metabolism and Disposition October 2020, 48 (10) 1104-1112; DOI: https://doi.org/10.1124/dmd.120.000054
  3. Ayyar, Vivaswath S.

    1. You have access
      Seeking Nonspecific Binding: Assessing the Reliability of Tissue Dilutions for Calculating Fraction Unbound
      William J. Jusko, Emilie A.G. Molins and Vivaswath S. Ayyar
      Drug Metabolism and Disposition October 2020, 48 (10) 894-902; DOI: https://doi.org/10.1124/dmd.120.000118

B

  1. Badrinarayanan, Akshay

    1. You have access
      Comparison of In Vitro to In Vivo Extrapolation Approaches for Predicting Transporter-Mediated Hepatic Uptake Clearance Using Suspended Rat Hepatocytes
      Na Li, Akshay Badrinarayanan, Xingwen Li, John Roberts, Mike Hayashi, Manpreet Virk and Anshul Gupta
      Drug Metabolism and Disposition October 2020, 48 (10) 861-872; DOI: https://doi.org/10.1124/dmd.120.000064
  2. Bakos, Éva

    1. You have access
      Effects of Chrysin and Its Major Conjugated Metabolites Chrysin-7-Sulfate and Chrysin-7-Glucuronide on Cytochrome P450 Enzymes and on OATP, P-gp, BCRP, and MRP2 Transporters
      Violetta Mohos, Eszter Fliszár-Nyúl, Orsolya Ungvári, Éva Bakos, Katalin Kuffa, Tímea Bencsik, Balázs Zoltán Zsidó, Csaba Hetényi, Ágnes Telbisz, Csilla Özvegy-Laczka and Miklós Poór
      Drug Metabolism and Disposition October 2020, 48 (10) 1064-1073; DOI: https://doi.org/10.1124/dmd.120.000085
  3. Banks, Troy T.

    1. You have access
      Centella asiatica Water Extract Shows Low Potential for Cytochrome P450–Mediated Drug Interactions
      Kirsten M. Wright, Armando Alcazar Magana, Ronald M. Laethem, Caroline L. Moseley, Troy T. Banks, Claudia S. Maier, Jan F. Stevens, Joseph F. Quinn and Amala Soumyanath
      Drug Metabolism and Disposition October 2020, 48 (10) 1053-1063; DOI: https://doi.org/10.1124/dmd.120.090860
  4. Bansal, Sumit

    1. You have access
      Predicting the Potential for Cannabinoids to Precipitate Pharmacokinetic Drug Interactions via Reversible Inhibition or Inactivation of Major Cytochromes P450
      Sumit Bansal, Neha Maharao, Mary F. Paine and Jashvant D. Unadkat
      Drug Metabolism and Disposition October 2020, 48 (10) 1008-1017; DOI: https://doi.org/10.1124/dmd.120.000073
  5. Bencsik, Tímea

    1. You have access
      Effects of Chrysin and Its Major Conjugated Metabolites Chrysin-7-Sulfate and Chrysin-7-Glucuronide on Cytochrome P450 Enzymes and on OATP, P-gp, BCRP, and MRP2 Transporters
      Violetta Mohos, Eszter Fliszár-Nyúl, Orsolya Ungvári, Éva Bakos, Katalin Kuffa, Tímea Bencsik, Balázs Zoltán Zsidó, Csaba Hetényi, Ágnes Telbisz, Csilla Özvegy-Laczka and Miklós Poór
      Drug Metabolism and Disposition October 2020, 48 (10) 1064-1073; DOI: https://doi.org/10.1124/dmd.120.000085
  6. Birer-Williams, Caroline

    1. Open Access
      A New Data Repository for Pharmacokinetic Natural Product-Drug Interactions: From Chemical Characterization to Clinical Studies
      Caroline Birer-Williams, Brandon T. Gufford, Eric Chou, Marijanel Alilio, Sidney VanAlstine, Rachael E. Morley, Jeannine S. McCune, Mary F. Paine and Richard D. Boyce
      Drug Metabolism and Disposition October 2020, 48 (10) 1104-1112; DOI: https://doi.org/10.1124/dmd.120.000054
  7. Bolleddula, Jayaprakasam

    1. You have access
      Prediction of Human Disproportionate and Biliary Excreted Metabolites Using Chimeric Mice with Humanized Liver
      Suguru Kato, Abhi Shah, Mihaela Plesescu, Yoshinari Miyata, Jayaprakasam Bolleddula, Swapan Chowdhury and Xiaochun Zhu
      Drug Metabolism and Disposition October 2020, 48 (10) 934-943; DOI: https://doi.org/10.1124/dmd.120.000128
  8. Borell, Hubert

    1. Open Access
      Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite
      Ulrike Glaenzel, Yi Jin, Regine Hansen, Kirsten Schroer, Gholamreza Rahmanzadeh, Ulrike Pfaar, Jan Jaap van Lier, Hubert Borell, Axel Meissner, Gian Camenisch and Sylvia Zhao
      Drug Metabolism and Disposition October 2020, 48 (10) 873-885; DOI: https://doi.org/10.1124/dmd.119.090324
  9. Boyce, Richard D.

    1. Open Access
      A New Data Repository for Pharmacokinetic Natural Product-Drug Interactions: From Chemical Characterization to Clinical Studies
      Caroline Birer-Williams, Brandon T. Gufford, Eric Chou, Marijanel Alilio, Sidney VanAlstine, Rachael E. Morley, Jeannine S. McCune, Mary F. Paine and Richard D. Boyce
      Drug Metabolism and Disposition October 2020, 48 (10) 1104-1112; DOI: https://doi.org/10.1124/dmd.120.000054

C

  1. Cai, Ying

    1. The Effects of Traditional Chinese Medicine on P-Glycoprotein–Mediated Multidrug Resistance and Approaches for Studying the Herb–P-Glycoprotein Interactions
      You have access
      The Effects of Traditional Chinese Medicine on P-Glycoprotein–Mediated Multidrug Resistance and Approaches for Studying the Herb–P-Glycoprotein Interactions
      Yuhong Cao, Yiwei Shi, Ying Cai, Zhanying Hong and Yifeng Chai
      Drug Metabolism and Disposition October 2020, 48 (10) 972-979; DOI: https://doi.org/10.1124/dmd.120.000050
  2. Cain, Meredith

    1. You have access
      A Study of the Effect of Cyclosporine on Fevipiprant Pharmacokinetics and its Absolute Bioavailability Using an Intravenous Microdose Approach
      H. Markus Weiss, Ken-Ichi Umehara, Veit J. Erpenbeck, Meredith Cain, Janardhana Vemula, Walid Elbast and Markus Zollinger
      Drug Metabolism and Disposition October 2020, 48 (10) 917-924; DOI: https://doi.org/10.1124/dmd.120.090852
  3. Camenisch, Gian

    1. Open Access
      Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite
      Ulrike Glaenzel, Yi Jin, Regine Hansen, Kirsten Schroer, Gholamreza Rahmanzadeh, Ulrike Pfaar, Jan Jaap van Lier, Hubert Borell, Axel Meissner, Gian Camenisch and Sylvia Zhao
      Drug Metabolism and Disposition October 2020, 48 (10) 873-885; DOI: https://doi.org/10.1124/dmd.119.090324
  4. Cantrill, Carina

    1. You have access
      Application of the Extended Clearance Classification System (ECCS) in Drug Discovery and Development: Selection of Appropriate In Vitro Tools and Clearance Prediction
      Kenichi Umehara, Carina Cantrill, Matthias Beat Wittwer, Elisa Di Lenarda, Florian Klammers, Aynur Ekiciler, Neil Parrott, Stephen Fowler and Mohammed Ullah
      Drug Metabolism and Disposition October 2020, 48 (10) 849-860; DOI: https://doi.org/10.1124/dmd.120.000133
  5. Cao, Yuhong

    1. The Effects of Traditional Chinese Medicine on P-Glycoprotein–Mediated Multidrug Resistance and Approaches for Studying the Herb–P-Glycoprotein Interactions
      You have access
      The Effects of Traditional Chinese Medicine on P-Glycoprotein–Mediated Multidrug Resistance and Approaches for Studying the Herb–P-Glycoprotein Interactions
      Yuhong Cao, Yiwei Shi, Ying Cai, Zhanying Hong and Yifeng Chai
      Drug Metabolism and Disposition October 2020, 48 (10) 972-979; DOI: https://doi.org/10.1124/dmd.120.000050
  6. Chai, Yifeng

    1. The Effects of Traditional Chinese Medicine on P-Glycoprotein–Mediated Multidrug Resistance and Approaches for Studying the Herb–P-Glycoprotein Interactions
      You have access
      The Effects of Traditional Chinese Medicine on P-Glycoprotein–Mediated Multidrug Resistance and Approaches for Studying the Herb–P-Glycoprotein Interactions
      Yuhong Cao, Yiwei Shi, Ying Cai, Zhanying Hong and Yifeng Chai
      Drug Metabolism and Disposition October 2020, 48 (10) 972-979; DOI: https://doi.org/10.1124/dmd.120.000050
  7. Chan, Jeannine M.

    1. You have access
      Mechanisms of Herb-Drug Interactions Involving Cinnamon and CYP2A6: Focus on Time-Dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde
      Michael J. Espiritu, Justin Chen, Jaydeep Yadav, Michael Larkin, Robert D. Pelletier, Jeannine M. Chan, Jeevan B. GC, Senthil Natesan and John P. Harrelson
      Drug Metabolism and Disposition October 2020, 48 (10) 1028-1043; DOI: https://doi.org/10.1124/dmd.120.000087
  8. Chang, Ya-Ning

    1. Preclinical Transplacental Transfer and Pharmacokinetics of Fipronil in Rats
      You have access
      Preclinical Transplacental Transfer and Pharmacokinetics of Fipronil in Rats
      Ya-Ning Chang and Tung-Hu Tsai
      Drug Metabolism and Disposition October 2020, 48 (10) 886-893; DOI: https://doi.org/10.1124/dmd.120.000088
  9. Chen, Justin

    1. You have access
      Mechanisms of Herb-Drug Interactions Involving Cinnamon and CYP2A6: Focus on Time-Dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde
      Michael J. Espiritu, Justin Chen, Jaydeep Yadav, Michael Larkin, Robert D. Pelletier, Jeannine M. Chan, Jeevan B. GC, Senthil Natesan and John P. Harrelson
      Drug Metabolism and Disposition October 2020, 48 (10) 1028-1043; DOI: https://doi.org/10.1124/dmd.120.000087
  10. Chen, Yingchun

    1. You have access
      Organic Cation Transporter 1 and 3 Contribute to the High Accumulation of Dehydrocorydaline in the Heart
      Yingchun Chen, Cui Li, Yaodong Yi, Weijuan Du, Huidi Jiang, Su Zeng and Hui Zhou
      Drug Metabolism and Disposition October 2020, 48 (10) 1074-1083; DOI: https://doi.org/10.1124/dmd.120.000025
  11. Chou, Eric

    1. Open Access
      A New Data Repository for Pharmacokinetic Natural Product-Drug Interactions: From Chemical Characterization to Clinical Studies
      Caroline Birer-Williams, Brandon T. Gufford, Eric Chou, Marijanel Alilio, Sidney VanAlstine, Rachael E. Morley, Jeannine S. McCune, Mary F. Paine and Richard D. Boyce
      Drug Metabolism and Disposition October 2020, 48 (10) 1104-1112; DOI: https://doi.org/10.1124/dmd.120.000054
  12. Chowdhury, Swapan

    1. You have access
      Prediction of Human Disproportionate and Biliary Excreted Metabolites Using Chimeric Mice with Humanized Liver
      Suguru Kato, Abhi Shah, Mihaela Plesescu, Yoshinari Miyata, Jayaprakasam Bolleddula, Swapan Chowdhury and Xiaochun Zhu
      Drug Metabolism and Disposition October 2020, 48 (10) 934-943; DOI: https://doi.org/10.1124/dmd.120.000128

D

  1. de Lannoy, Inés A.M.

    1. You have access
      Human Amyloid-β40 Kinetics after Intravenous and Intracerebroventricular Injections and Calcitriol Treatment in Rats In Vivo
      H. Benson Peng, Keumhan Noh, Sophie R. Pan, Victor Saldivia, Sylvia Serson, Anja Toscan, Inés A.M. de Lannoy and K. Sandy Pang
      Drug Metabolism and Disposition October 2020, 48 (10) 944-955; DOI: https://doi.org/10.1124/dmd.120.090886
  2. Di Lenarda, Elisa

    1. You have access
      Application of the Extended Clearance Classification System (ECCS) in Drug Discovery and Development: Selection of Appropriate In Vitro Tools and Clearance Prediction
      Kenichi Umehara, Carina Cantrill, Matthias Beat Wittwer, Elisa Di Lenarda, Florian Klammers, Aynur Ekiciler, Neil Parrott, Stephen Fowler and Mohammed Ullah
      Drug Metabolism and Disposition October 2020, 48 (10) 849-860; DOI: https://doi.org/10.1124/dmd.120.000133
  3. Ding, Qingqing

    1. Multiomics Profiling Reveals Protective Function of <em>Schisandra</em> Lignans against Acetaminophen-Induced Hepatotoxicity
      You have access
      Multiomics Profiling Reveals Protective Function of Schisandra Lignans against Acetaminophen-Induced Hepatotoxicity
      Caixia Yan, Huimin Guo, Qingqing Ding, Yuhao Shao, Dian Kang, Tengjie Yu, Changjian Li, Haoran Huang, Yisha Du, He Wang, Kangrui Hu, Lin Xie, Guangji Wang and Yan Liang
      Drug Metabolism and Disposition October 2020, 48 (10) 1092-1103; DOI: https://doi.org/10.1124/dmd.120.000083
  4. Du, Weijuan

    1. You have access
      Organic Cation Transporter 1 and 3 Contribute to the High Accumulation of Dehydrocorydaline in the Heart
      Yingchun Chen, Cui Li, Yaodong Yi, Weijuan Du, Huidi Jiang, Su Zeng and Hui Zhou
      Drug Metabolism and Disposition October 2020, 48 (10) 1074-1083; DOI: https://doi.org/10.1124/dmd.120.000025
  5. Du, Yisha

    1. Multiomics Profiling Reveals Protective Function of <em>Schisandra</em> Lignans against Acetaminophen-Induced Hepatotoxicity
      You have access
      Multiomics Profiling Reveals Protective Function of Schisandra Lignans against Acetaminophen-Induced Hepatotoxicity
      Caixia Yan, Huimin Guo, Qingqing Ding, Yuhao Shao, Dian Kang, Tengjie Yu, Changjian Li, Haoran Huang, Yisha Du, He Wang, Kangrui Hu, Lin Xie, Guangji Wang and Yan Liang
      Drug Metabolism and Disposition October 2020, 48 (10) 1092-1103; DOI: https://doi.org/10.1124/dmd.120.000083

E

  1. Ekiciler, Aynur

    1. You have access
      Application of the Extended Clearance Classification System (ECCS) in Drug Discovery and Development: Selection of Appropriate In Vitro Tools and Clearance Prediction
      Kenichi Umehara, Carina Cantrill, Matthias Beat Wittwer, Elisa Di Lenarda, Florian Klammers, Aynur Ekiciler, Neil Parrott, Stephen Fowler and Mohammed Ullah
      Drug Metabolism and Disposition October 2020, 48 (10) 849-860; DOI: https://doi.org/10.1124/dmd.120.000133
  2. Elbast, Walid

    1. You have access
      A Study of the Effect of Cyclosporine on Fevipiprant Pharmacokinetics and its Absolute Bioavailability Using an Intravenous Microdose Approach
      H. Markus Weiss, Ken-Ichi Umehara, Veit J. Erpenbeck, Meredith Cain, Janardhana Vemula, Walid Elbast and Markus Zollinger
      Drug Metabolism and Disposition October 2020, 48 (10) 917-924; DOI: https://doi.org/10.1124/dmd.120.090852
  3. Elmokadem, Ahmed

    1. Open Access
      Quantification of the Impact of Partition Coefficient Prediction Methods on Physiologically Based Pharmacokinetic Model Output Using a Standardized Tissue Composition
      Kiersten Utsey, Madeleine S. Gastonguay, Sean Russell, Reed Freling, Matthew M. Riggs and Ahmed Elmokadem
      Drug Metabolism and Disposition October 2020, 48 (10) 903-916; DOI: https://doi.org/10.1124/dmd.120.090498
  4. Erpenbeck, Veit J.

    1. You have access
      A Study of the Effect of Cyclosporine on Fevipiprant Pharmacokinetics and its Absolute Bioavailability Using an Intravenous Microdose Approach
      H. Markus Weiss, Ken-Ichi Umehara, Veit J. Erpenbeck, Meredith Cain, Janardhana Vemula, Walid Elbast and Markus Zollinger
      Drug Metabolism and Disposition October 2020, 48 (10) 917-924; DOI: https://doi.org/10.1124/dmd.120.090852
  5. Espiritu, Michael J.

    1. You have access
      Mechanisms of Herb-Drug Interactions Involving Cinnamon and CYP2A6: Focus on Time-Dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde
      Michael J. Espiritu, Justin Chen, Jaydeep Yadav, Michael Larkin, Robert D. Pelletier, Jeannine M. Chan, Jeevan B. GC, Senthil Natesan and John P. Harrelson
      Drug Metabolism and Disposition October 2020, 48 (10) 1028-1043; DOI: https://doi.org/10.1124/dmd.120.000087

F

  1. Fliszár-Nyúl, Eszter

    1. You have access
      Effects of Chrysin and Its Major Conjugated Metabolites Chrysin-7-Sulfate and Chrysin-7-Glucuronide on Cytochrome P450 Enzymes and on OATP, P-gp, BCRP, and MRP2 Transporters
      Violetta Mohos, Eszter Fliszár-Nyúl, Orsolya Ungvári, Éva Bakos, Katalin Kuffa, Tímea Bencsik, Balázs Zoltán Zsidó, Csaba Hetényi, Ágnes Telbisz, Csilla Özvegy-Laczka and Miklós Poór
      Drug Metabolism and Disposition October 2020, 48 (10) 1064-1073; DOI: https://doi.org/10.1124/dmd.120.000085
  2. Fowler, Stephen

    1. You have access
      Application of the Extended Clearance Classification System (ECCS) in Drug Discovery and Development: Selection of Appropriate In Vitro Tools and Clearance Prediction
      Kenichi Umehara, Carina Cantrill, Matthias Beat Wittwer, Elisa Di Lenarda, Florian Klammers, Aynur Ekiciler, Neil Parrott, Stephen Fowler and Mohammed Ullah
      Drug Metabolism and Disposition October 2020, 48 (10) 849-860; DOI: https://doi.org/10.1124/dmd.120.000133
  3. Freling, Reed

    1. Open Access
      Quantification of the Impact of Partition Coefficient Prediction Methods on Physiologically Based Pharmacokinetic Model Output Using a Standardized Tissue Composition
      Kiersten Utsey, Madeleine S. Gastonguay, Sean Russell, Reed Freling, Matthew M. Riggs and Ahmed Elmokadem
      Drug Metabolism and Disposition October 2020, 48 (10) 903-916; DOI: https://doi.org/10.1124/dmd.120.090498

G

  1. Gastonguay, Madeleine S.

    1. Open Access
      Quantification of the Impact of Partition Coefficient Prediction Methods on Physiologically Based Pharmacokinetic Model Output Using a Standardized Tissue Composition
      Kiersten Utsey, Madeleine S. Gastonguay, Sean Russell, Reed Freling, Matthew M. Riggs and Ahmed Elmokadem
      Drug Metabolism and Disposition October 2020, 48 (10) 903-916; DOI: https://doi.org/10.1124/dmd.120.090498
  2. GC, Jeevan B.

    1. You have access
      Mechanisms of Herb-Drug Interactions Involving Cinnamon and CYP2A6: Focus on Time-Dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde
      Michael J. Espiritu, Justin Chen, Jaydeep Yadav, Michael Larkin, Robert D. Pelletier, Jeannine M. Chan, Jeevan B. GC, Senthil Natesan and John P. Harrelson
      Drug Metabolism and Disposition October 2020, 48 (10) 1028-1043; DOI: https://doi.org/10.1124/dmd.120.000087
  3. Glaenzel, Ulrike

    1. Open Access
      Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite
      Ulrike Glaenzel, Yi Jin, Regine Hansen, Kirsten Schroer, Gholamreza Rahmanzadeh, Ulrike Pfaar, Jan Jaap van Lier, Hubert Borell, Axel Meissner, Gian Camenisch and Sylvia Zhao
      Drug Metabolism and Disposition October 2020, 48 (10) 873-885; DOI: https://doi.org/10.1124/dmd.119.090324
  4. Gufford, Brandon T.

    1. Open Access
      A New Data Repository for Pharmacokinetic Natural Product-Drug Interactions: From Chemical Characterization to Clinical Studies
      Caroline Birer-Williams, Brandon T. Gufford, Eric Chou, Marijanel Alilio, Sidney VanAlstine, Rachael E. Morley, Jeannine S. McCune, Mary F. Paine and Richard D. Boyce
      Drug Metabolism and Disposition October 2020, 48 (10) 1104-1112; DOI: https://doi.org/10.1124/dmd.120.000054
  5. Guo, Huimin

    1. Multiomics Profiling Reveals Protective Function of <em>Schisandra</em> Lignans against Acetaminophen-Induced Hepatotoxicity
      You have access
      Multiomics Profiling Reveals Protective Function of Schisandra Lignans against Acetaminophen-Induced Hepatotoxicity
      Caixia Yan, Huimin Guo, Qingqing Ding, Yuhao Shao, Dian Kang, Tengjie Yu, Changjian Li, Haoran Huang, Yisha Du, He Wang, Kangrui Hu, Lin Xie, Guangji Wang and Yan Liang
      Drug Metabolism and Disposition October 2020, 48 (10) 1092-1103; DOI: https://doi.org/10.1124/dmd.120.000083
  6. Gupta, Anshul

    1. You have access
      Comparison of In Vitro to In Vivo Extrapolation Approaches for Predicting Transporter-Mediated Hepatic Uptake Clearance Using Suspended Rat Hepatocytes
      Na Li, Akshay Badrinarayanan, Xingwen Li, John Roberts, Mike Hayashi, Manpreet Virk and Anshul Gupta
      Drug Metabolism and Disposition October 2020, 48 (10) 861-872; DOI: https://doi.org/10.1124/dmd.120.000064

H

  1. Hansen, Regine

    1. Open Access
      Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite
      Ulrike Glaenzel, Yi Jin, Regine Hansen, Kirsten Schroer, Gholamreza Rahmanzadeh, Ulrike Pfaar, Jan Jaap van Lier, Hubert Borell, Axel Meissner, Gian Camenisch and Sylvia Zhao
      Drug Metabolism and Disposition October 2020, 48 (10) 873-885; DOI: https://doi.org/10.1124/dmd.119.090324
  2. Harrelson, John P.

    1. You have access
      Mechanisms of Herb-Drug Interactions Involving Cinnamon and CYP2A6: Focus on Time-Dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde
      Michael J. Espiritu, Justin Chen, Jaydeep Yadav, Michael Larkin, Robert D. Pelletier, Jeannine M. Chan, Jeevan B. GC, Senthil Natesan and John P. Harrelson
      Drug Metabolism and Disposition October 2020, 48 (10) 1028-1043; DOI: https://doi.org/10.1124/dmd.120.000087
  3. Hayashi, Mike

    1. You have access
      Comparison of In Vitro to In Vivo Extrapolation Approaches for Predicting Transporter-Mediated Hepatic Uptake Clearance Using Suspended Rat Hepatocytes
      Na Li, Akshay Badrinarayanan, Xingwen Li, John Roberts, Mike Hayashi, Manpreet Virk and Anshul Gupta
      Drug Metabolism and Disposition October 2020, 48 (10) 861-872; DOI: https://doi.org/10.1124/dmd.120.000064
  4. Hetényi, Csaba

    1. You have access
      Effects of Chrysin and Its Major Conjugated Metabolites Chrysin-7-Sulfate and Chrysin-7-Glucuronide on Cytochrome P450 Enzymes and on OATP, P-gp, BCRP, and MRP2 Transporters
      Violetta Mohos, Eszter Fliszár-Nyúl, Orsolya Ungvári, Éva Bakos, Katalin Kuffa, Tímea Bencsik, Balázs Zoltán Zsidó, Csaba Hetényi, Ágnes Telbisz, Csilla Özvegy-Laczka and Miklós Poór
      Drug Metabolism and Disposition October 2020, 48 (10) 1064-1073; DOI: https://doi.org/10.1124/dmd.120.000085
  5. Ho, Ming-Chih David

    1. You have access
      Application of Cryopreserved Human Intestinal Mucosa and Cryopreserved Human Enterocytes in the Evaluation of Herb-Drug Interactions: Evaluation of CYP3A Inhibitory Potential of Grapefruit Juice and Commercial Formulations of Twenty-Nine Herbal Supplements
      Carol Loretz, Ming-Chih David Ho, Novera Alam, Walter Mitchell and Albert P. Li
      Drug Metabolism and Disposition October 2020, 48 (10) 1084-1091; DOI: https://doi.org/10.1124/dmd.120.000033
  6. Holenarsipur, Vinay K.

    1. You have access
      Detection of Weak Organic Anion–Transporting Polypeptide 1B Inhibition by Probenecid with Plasma-Based Coproporphyrin in Humans
      Yueping Zhang, Vinay K. Holenarsipur, Hamza Kandoussi, Jianing Zeng, T. Thanga Mariappan, Michael Sinz and Hong Shen
      Drug Metabolism and Disposition October 2020, 48 (10) 841-848; DOI: https://doi.org/10.1124/dmd.120.000076
  7. Hong, Zhanying

    1. The Effects of Traditional Chinese Medicine on P-Glycoprotein–Mediated Multidrug Resistance and Approaches for Studying the Herb–P-Glycoprotein Interactions
      You have access
      The Effects of Traditional Chinese Medicine on P-Glycoprotein–Mediated Multidrug Resistance and Approaches for Studying the Herb–P-Glycoprotein Interactions
      Yuhong Cao, Yiwei Shi, Ying Cai, Zhanying Hong and Yifeng Chai
      Drug Metabolism and Disposition October 2020, 48 (10) 972-979; DOI: https://doi.org/10.1124/dmd.120.000050
  8. Hopp, D. Craig

    1. You have access
      National Center for Complementary and Integrative Health Perspectives on Clinical Research Involving Natural Products
      Wendy J. Weber and D. Craig Hopp
      Drug Metabolism and Disposition October 2020, 48 (10) 963-965; DOI: https://doi.org/10.1124/dmd.120.000071
  9. Hu, Kangrui

    1. Multiomics Profiling Reveals Protective Function of <em>Schisandra</em> Lignans against Acetaminophen-Induced Hepatotoxicity
      You have access
      Multiomics Profiling Reveals Protective Function of Schisandra Lignans against Acetaminophen-Induced Hepatotoxicity
      Caixia Yan, Huimin Guo, Qingqing Ding, Yuhao Shao, Dian Kang, Tengjie Yu, Changjian Li, Haoran Huang, Yisha Du, He Wang, Kangrui Hu, Lin Xie, Guangji Wang and Yan Liang
      Drug Metabolism and Disposition October 2020, 48 (10) 1092-1103; DOI: https://doi.org/10.1124/dmd.120.000083
  10. Huang, Haoran

    1. Multiomics Profiling Reveals Protective Function of <em>Schisandra</em> Lignans against Acetaminophen-Induced Hepatotoxicity
      You have access
      Multiomics Profiling Reveals Protective Function of Schisandra Lignans against Acetaminophen-Induced Hepatotoxicity
      Caixia Yan, Huimin Guo, Qingqing Ding, Yuhao Shao, Dian Kang, Tengjie Yu, Changjian Li, Haoran Huang, Yisha Du, He Wang, Kangrui Hu, Lin Xie, Guangji Wang and Yan Liang
      Drug Metabolism and Disposition October 2020, 48 (10) 1092-1103; DOI: https://doi.org/10.1124/dmd.120.000083

J

  1. Jaap van Lier, Jan

    1. Open Access
      Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite
      Ulrike Glaenzel, Yi Jin, Regine Hansen, Kirsten Schroer, Gholamreza Rahmanzadeh, Ulrike Pfaar, Jan Jaap van Lier, Hubert Borell, Axel Meissner, Gian Camenisch and Sylvia Zhao
      Drug Metabolism and Disposition October 2020, 48 (10) 873-885; DOI: https://doi.org/10.1124/dmd.119.090324
  2. Ji, Jin-Zi

    1. Multidrug Resistance–Associated Protein 3 Is Responsible for the Efflux Transport of Curcumin Glucuronide from Hepatocytes to the Blood
      You have access
      Multidrug Resistance–Associated Protein 3 Is Responsible for the Efflux Transport of Curcumin Glucuronide from Hepatocytes to the Blood
      Yu-Meng Jia, Ting Zhu, Huan Zhou, Jin-Zi Ji, Ting Tai and Hong-Guang Xie
      Drug Metabolism and Disposition October 2020, 48 (10) 966-971; DOI: https://doi.org/10.1124/dmd.119.089193
  3. Jia, Yu-Meng

    1. Multidrug Resistance–Associated Protein 3 Is Responsible for the Efflux Transport of Curcumin Glucuronide from Hepatocytes to the Blood
      You have access
      Multidrug Resistance–Associated Protein 3 Is Responsible for the Efflux Transport of Curcumin Glucuronide from Hepatocytes to the Blood
      Yu-Meng Jia, Ting Zhu, Huan Zhou, Jin-Zi Ji, Ting Tai and Hong-Guang Xie
      Drug Metabolism and Disposition October 2020, 48 (10) 966-971; DOI: https://doi.org/10.1124/dmd.119.089193
  4. Jiang, Huidi

    1. You have access
      Organic Cation Transporter 1 and 3 Contribute to the High Accumulation of Dehydrocorydaline in the Heart
      Yingchun Chen, Cui Li, Yaodong Yi, Weijuan Du, Huidi Jiang, Su Zeng and Hui Zhou
      Drug Metabolism and Disposition October 2020, 48 (10) 1074-1083; DOI: https://doi.org/10.1124/dmd.120.000025
  5. Jin, Jingyi

    1. You have access
      Influence of Zuojin Pill on the Metabolism of Venlafaxine in Vitro and in Rats and Associated Herb-Drug Interaction
      Yue Li, Juan Li, Dongmin Yan, Qian Wang, Jingyi Jin, Bo Tan and Furong Qiu
      Drug Metabolism and Disposition October 2020, 48 (10) 1044-1052; DOI: https://doi.org/10.1124/dmd.120.000048
  6. Jin, Yi

    1. Open Access
      Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite
      Ulrike Glaenzel, Yi Jin, Regine Hansen, Kirsten Schroer, Gholamreza Rahmanzadeh, Ulrike Pfaar, Jan Jaap van Lier, Hubert Borell, Axel Meissner, Gian Camenisch and Sylvia Zhao
      Drug Metabolism and Disposition October 2020, 48 (10) 873-885; DOI: https://doi.org/10.1124/dmd.119.090324
  7. Jusko, William J.

    1. You have access
      Seeking Nonspecific Binding: Assessing the Reliability of Tissue Dilutions for Calculating Fraction Unbound
      William J. Jusko, Emilie A.G. Molins and Vivaswath S. Ayyar
      Drug Metabolism and Disposition October 2020, 48 (10) 894-902; DOI: https://doi.org/10.1124/dmd.120.000118

K

  1. Kandoussi, Hamza

    1. You have access
      Detection of Weak Organic Anion–Transporting Polypeptide 1B Inhibition by Probenecid with Plasma-Based Coproporphyrin in Humans
      Yueping Zhang, Vinay K. Holenarsipur, Hamza Kandoussi, Jianing Zeng, T. Thanga Mariappan, Michael Sinz and Hong Shen
      Drug Metabolism and Disposition October 2020, 48 (10) 841-848; DOI: https://doi.org/10.1124/dmd.120.000076
  2. Kang, Dian

    1. Multiomics Profiling Reveals Protective Function of <em>Schisandra</em> Lignans against Acetaminophen-Induced Hepatotoxicity
      You have access
      Multiomics Profiling Reveals Protective Function of Schisandra Lignans against Acetaminophen-Induced Hepatotoxicity
      Caixia Yan, Huimin Guo, Qingqing Ding, Yuhao Shao, Dian Kang, Tengjie Yu, Changjian Li, Haoran Huang, Yisha Du, He Wang, Kangrui Hu, Lin Xie, Guangji Wang and Yan Liang
      Drug Metabolism and Disposition October 2020, 48 (10) 1092-1103; DOI: https://doi.org/10.1124/dmd.120.000083
  3. Kato, Suguru

    1. You have access
      Prediction of Human Disproportionate and Biliary Excreted Metabolites Using Chimeric Mice with Humanized Liver
      Suguru Kato, Abhi Shah, Mihaela Plesescu, Yoshinari Miyata, Jayaprakasam Bolleddula, Swapan Chowdhury and Xiaochun Zhu
      Drug Metabolism and Disposition October 2020, 48 (10) 934-943; DOI: https://doi.org/10.1124/dmd.120.000128
  4. Klammers, Florian

    1. You have access
      Application of the Extended Clearance Classification System (ECCS) in Drug Discovery and Development: Selection of Appropriate In Vitro Tools and Clearance Prediction
      Kenichi Umehara, Carina Cantrill, Matthias Beat Wittwer, Elisa Di Lenarda, Florian Klammers, Aynur Ekiciler, Neil Parrott, Stephen Fowler and Mohammed Ullah
      Drug Metabolism and Disposition October 2020, 48 (10) 849-860; DOI: https://doi.org/10.1124/dmd.120.000133
  5. Kuffa, Katalin

    1. You have access
      Effects of Chrysin and Its Major Conjugated Metabolites Chrysin-7-Sulfate and Chrysin-7-Glucuronide on Cytochrome P450 Enzymes and on OATP, P-gp, BCRP, and MRP2 Transporters
      Violetta Mohos, Eszter Fliszár-Nyúl, Orsolya Ungvári, Éva Bakos, Katalin Kuffa, Tímea Bencsik, Balázs Zoltán Zsidó, Csaba Hetényi, Ágnes Telbisz, Csilla Özvegy-Laczka and Miklós Poór
      Drug Metabolism and Disposition October 2020, 48 (10) 1064-1073; DOI: https://doi.org/10.1124/dmd.120.000085

L

  1. Laethem, Ronald M.

    1. You have access
      Centella asiatica Water Extract Shows Low Potential for Cytochrome P450–Mediated Drug Interactions
      Kirsten M. Wright, Armando Alcazar Magana, Ronald M. Laethem, Caroline L. Moseley, Troy T. Banks, Claudia S. Maier, Jan F. Stevens, Joseph F. Quinn and Amala Soumyanath
      Drug Metabolism and Disposition October 2020, 48 (10) 1053-1063; DOI: https://doi.org/10.1124/dmd.120.090860
  2. Larkin, Michael

    1. You have access
      Mechanisms of Herb-Drug Interactions Involving Cinnamon and CYP2A6: Focus on Time-Dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde
      Michael J. Espiritu, Justin Chen, Jaydeep Yadav, Michael Larkin, Robert D. Pelletier, Jeannine M. Chan, Jeevan B. GC, Senthil Natesan and John P. Harrelson
      Drug Metabolism and Disposition October 2020, 48 (10) 1028-1043; DOI: https://doi.org/10.1124/dmd.120.000087
  3. Li, Albert P.

    1. You have access
      Application of Cryopreserved Human Intestinal Mucosa and Cryopreserved Human Enterocytes in the Evaluation of Herb-Drug Interactions: Evaluation of CYP3A Inhibitory Potential of Grapefruit Juice and Commercial Formulations of Twenty-Nine Herbal Supplements
      Carol Loretz, Ming-Chih David Ho, Novera Alam, Walter Mitchell and Albert P. Li
      Drug Metabolism and Disposition October 2020, 48 (10) 1084-1091; DOI: https://doi.org/10.1124/dmd.120.000033
    2. You have access
      In Vitro Human Cell–Based Experimental Models for the Evaluation of Enteric Metabolism and Drug Interaction Potential of Drugs and Natural Products
      Albert P. Li
      Drug Metabolism and Disposition October 2020, 48 (10) 980-992; DOI: https://doi.org/10.1124/dmd.120.000053
  4. Li, Changjian

    1. Multiomics Profiling Reveals Protective Function of <em>Schisandra</em> Lignans against Acetaminophen-Induced Hepatotoxicity
      You have access
      Multiomics Profiling Reveals Protective Function of Schisandra Lignans against Acetaminophen-Induced Hepatotoxicity
      Caixia Yan, Huimin Guo, Qingqing Ding, Yuhao Shao, Dian Kang, Tengjie Yu, Changjian Li, Haoran Huang, Yisha Du, He Wang, Kangrui Hu, Lin Xie, Guangji Wang and Yan Liang
      Drug Metabolism and Disposition October 2020, 48 (10) 1092-1103; DOI: https://doi.org/10.1124/dmd.120.000083
  5. Li, Cui

    1. You have access
      Organic Cation Transporter 1 and 3 Contribute to the High Accumulation of Dehydrocorydaline in the Heart
      Yingchun Chen, Cui Li, Yaodong Yi, Weijuan Du, Huidi Jiang, Su Zeng and Hui Zhou
      Drug Metabolism and Disposition October 2020, 48 (10) 1074-1083; DOI: https://doi.org/10.1124/dmd.120.000025
  6. Li, Juan

    1. You have access
      Influence of Zuojin Pill on the Metabolism of Venlafaxine in Vitro and in Rats and Associated Herb-Drug Interaction
      Yue Li, Juan Li, Dongmin Yan, Qian Wang, Jingyi Jin, Bo Tan and Furong Qiu
      Drug Metabolism and Disposition October 2020, 48 (10) 1044-1052; DOI: https://doi.org/10.1124/dmd.120.000048
  7. Li, Na

    1. You have access
      Comparison of In Vitro to In Vivo Extrapolation Approaches for Predicting Transporter-Mediated Hepatic Uptake Clearance Using Suspended Rat Hepatocytes
      Na Li, Akshay Badrinarayanan, Xingwen Li, John Roberts, Mike Hayashi, Manpreet Virk and Anshul Gupta
      Drug Metabolism and Disposition October 2020, 48 (10) 861-872; DOI: https://doi.org/10.1124/dmd.120.000064
  8. Li, Xingwen

    1. You have access
      Comparison of In Vitro to In Vivo Extrapolation Approaches for Predicting Transporter-Mediated Hepatic Uptake Clearance Using Suspended Rat Hepatocytes
      Na Li, Akshay Badrinarayanan, Xingwen Li, John Roberts, Mike Hayashi, Manpreet Virk and Anshul Gupta
      Drug Metabolism and Disposition October 2020, 48 (10) 861-872; DOI: https://doi.org/10.1124/dmd.120.000064
  9. Li, Yue

    1. You have access
      Influence of Zuojin Pill on the Metabolism of Venlafaxine in Vitro and in Rats and Associated Herb-Drug Interaction
      Yue Li, Juan Li, Dongmin Yan, Qian Wang, Jingyi Jin, Bo Tan and Furong Qiu
      Drug Metabolism and Disposition October 2020, 48 (10) 1044-1052; DOI: https://doi.org/10.1124/dmd.120.000048
  10. Liang, Yan

    1. Multiomics Profiling Reveals Protective Function of <em>Schisandra</em> Lignans against Acetaminophen-Induced Hepatotoxicity
      You have access
      Multiomics Profiling Reveals Protective Function of Schisandra Lignans against Acetaminophen-Induced Hepatotoxicity
      Caixia Yan, Huimin Guo, Qingqing Ding, Yuhao Shao, Dian Kang, Tengjie Yu, Changjian Li, Haoran Huang, Yisha Du, He Wang, Kangrui Hu, Lin Xie, Guangji Wang and Yan Liang
      Drug Metabolism and Disposition October 2020, 48 (10) 1092-1103; DOI: https://doi.org/10.1124/dmd.120.000083
  11. Loretz, Carol

    1. You have access
      Application of Cryopreserved Human Intestinal Mucosa and Cryopreserved Human Enterocytes in the Evaluation of Herb-Drug Interactions: Evaluation of CYP3A Inhibitory Potential of Grapefruit Juice and Commercial Formulations of Twenty-Nine Herbal Supplements
      Carol Loretz, Ming-Chih David Ho, Novera Alam, Walter Mitchell and Albert P. Li
      Drug Metabolism and Disposition October 2020, 48 (10) 1084-1091; DOI: https://doi.org/10.1124/dmd.120.000033

M

  1. Magana, Armando Alcazar

    1. You have access
      Centella asiatica Water Extract Shows Low Potential for Cytochrome P450–Mediated Drug Interactions
      Kirsten M. Wright, Armando Alcazar Magana, Ronald M. Laethem, Caroline L. Moseley, Troy T. Banks, Claudia S. Maier, Jan F. Stevens, Joseph F. Quinn and Amala Soumyanath
      Drug Metabolism and Disposition October 2020, 48 (10) 1053-1063; DOI: https://doi.org/10.1124/dmd.120.090860
  2. Maharao, Neha

    1. You have access
      Predicting the Potential for Cannabinoids to Precipitate Pharmacokinetic Drug Interactions via Reversible Inhibition or Inactivation of Major Cytochromes P450
      Sumit Bansal, Neha Maharao, Mary F. Paine and Jashvant D. Unadkat
      Drug Metabolism and Disposition October 2020, 48 (10) 1008-1017; DOI: https://doi.org/10.1124/dmd.120.000073
  3. Maier, Claudia S.

    1. You have access
      Centella asiatica Water Extract Shows Low Potential for Cytochrome P450–Mediated Drug Interactions
      Kirsten M. Wright, Armando Alcazar Magana, Ronald M. Laethem, Caroline L. Moseley, Troy T. Banks, Claudia S. Maier, Jan F. Stevens, Joseph F. Quinn and Amala Soumyanath
      Drug Metabolism and Disposition October 2020, 48 (10) 1053-1063; DOI: https://doi.org/10.1124/dmd.120.090860
  4. Mariappan, T. Thanga

    1. You have access
      Detection of Weak Organic Anion–Transporting Polypeptide 1B Inhibition by Probenecid with Plasma-Based Coproporphyrin in Humans
      Yueping Zhang, Vinay K. Holenarsipur, Hamza Kandoussi, Jianing Zeng, T. Thanga Mariappan, Michael Sinz and Hong Shen
      Drug Metabolism and Disposition October 2020, 48 (10) 841-848; DOI: https://doi.org/10.1124/dmd.120.000076
  5. Markowitz, John S.

    1. You have access
      Natural Products as Modulators of CES1 Activity
      Yuli Qian and John S. Markowitz
      Drug Metabolism and Disposition October 2020, 48 (10) 993-1007; DOI: https://doi.org/10.1124/dmd.120.000065
  6. McCune, Jeannine S.

    1. Open Access
      A New Data Repository for Pharmacokinetic Natural Product-Drug Interactions: From Chemical Characterization to Clinical Studies
      Caroline Birer-Williams, Brandon T. Gufford, Eric Chou, Marijanel Alilio, Sidney VanAlstine, Rachael E. Morley, Jeannine S. McCune, Mary F. Paine and Richard D. Boyce
      Drug Metabolism and Disposition October 2020, 48 (10) 1104-1112; DOI: https://doi.org/10.1124/dmd.120.000054
  7. McDonald, Matthew G.

    1. You have access
      Modulation of Major Human Liver Microsomal Cytochromes P450 by Component Alkaloids of Goldenseal: Time-Dependent Inhibition and Allosteric Effects
      Matthew G. McDonald, Dan-Dan Tian, Kenneth E. Thummel, Mary F. Paine and Allan E. Rettie
      Drug Metabolism and Disposition October 2020, 48 (10) 1018-1027; DOI: https://doi.org/10.1124/dmd.120.091041
  8. Meissner, Axel

    1. Open Access
      Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite
      Ulrike Glaenzel, Yi Jin, Regine Hansen, Kirsten Schroer, Gholamreza Rahmanzadeh, Ulrike Pfaar, Jan Jaap van Lier, Hubert Borell, Axel Meissner, Gian Camenisch and Sylvia Zhao
      Drug Metabolism and Disposition October 2020, 48 (10) 873-885; DOI: https://doi.org/10.1124/dmd.119.090324
  9. Mitchell, Walter

    1. You have access
      Application of Cryopreserved Human Intestinal Mucosa and Cryopreserved Human Enterocytes in the Evaluation of Herb-Drug Interactions: Evaluation of CYP3A Inhibitory Potential of Grapefruit Juice and Commercial Formulations of Twenty-Nine Herbal Supplements
      Carol Loretz, Ming-Chih David Ho, Novera Alam, Walter Mitchell and Albert P. Li
      Drug Metabolism and Disposition October 2020, 48 (10) 1084-1091; DOI: https://doi.org/10.1124/dmd.120.000033
  10. Miyata, Yoshinari

    1. You have access
      Prediction of Human Disproportionate and Biliary Excreted Metabolites Using Chimeric Mice with Humanized Liver
      Suguru Kato, Abhi Shah, Mihaela Plesescu, Yoshinari Miyata, Jayaprakasam Bolleddula, Swapan Chowdhury and Xiaochun Zhu
      Drug Metabolism and Disposition October 2020, 48 (10) 934-943; DOI: https://doi.org/10.1124/dmd.120.000128
  11. Mohos, Violetta

    1. You have access
      Effects of Chrysin and Its Major Conjugated Metabolites Chrysin-7-Sulfate and Chrysin-7-Glucuronide on Cytochrome P450 Enzymes and on OATP, P-gp, BCRP, and MRP2 Transporters
      Violetta Mohos, Eszter Fliszár-Nyúl, Orsolya Ungvári, Éva Bakos, Katalin Kuffa, Tímea Bencsik, Balázs Zoltán Zsidó, Csaba Hetényi, Ágnes Telbisz, Csilla Özvegy-Laczka and Miklós Poór
      Drug Metabolism and Disposition October 2020, 48 (10) 1064-1073; DOI: https://doi.org/10.1124/dmd.120.000085
  12. Molins, Emilie A.G.

    1. You have access
      Seeking Nonspecific Binding: Assessing the Reliability of Tissue Dilutions for Calculating Fraction Unbound
      William J. Jusko, Emilie A.G. Molins and Vivaswath S. Ayyar
      Drug Metabolism and Disposition October 2020, 48 (10) 894-902; DOI: https://doi.org/10.1124/dmd.120.000118
  13. Morley, Rachael E.

    1. Open Access
      A New Data Repository for Pharmacokinetic Natural Product-Drug Interactions: From Chemical Characterization to Clinical Studies
      Caroline Birer-Williams, Brandon T. Gufford, Eric Chou, Marijanel Alilio, Sidney VanAlstine, Rachael E. Morley, Jeannine S. McCune, Mary F. Paine and Richard D. Boyce
      Drug Metabolism and Disposition October 2020, 48 (10) 1104-1112; DOI: https://doi.org/10.1124/dmd.120.000054
  14. Moseley, Caroline L.

    1. You have access
      Centella asiatica Water Extract Shows Low Potential for Cytochrome P450–Mediated Drug Interactions
      Kirsten M. Wright, Armando Alcazar Magana, Ronald M. Laethem, Caroline L. Moseley, Troy T. Banks, Claudia S. Maier, Jan F. Stevens, Joseph F. Quinn and Amala Soumyanath
      Drug Metabolism and Disposition October 2020, 48 (10) 1053-1063; DOI: https://doi.org/10.1124/dmd.120.090860

N

  1. Natesan, Senthil

    1. You have access
      Mechanisms of Herb-Drug Interactions Involving Cinnamon and CYP2A6: Focus on Time-Dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde
      Michael J. Espiritu, Justin Chen, Jaydeep Yadav, Michael Larkin, Robert D. Pelletier, Jeannine M. Chan, Jeevan B. GC, Senthil Natesan and John P. Harrelson
      Drug Metabolism and Disposition October 2020, 48 (10) 1028-1043; DOI: https://doi.org/10.1124/dmd.120.000087
  2. Noh, Keumhan

    1. You have access
      Human Amyloid-β40 Kinetics after Intravenous and Intracerebroventricular Injections and Calcitriol Treatment in Rats In Vivo
      H. Benson Peng, Keumhan Noh, Sophie R. Pan, Victor Saldivia, Sylvia Serson, Anja Toscan, Inés A.M. de Lannoy and K. Sandy Pang
      Drug Metabolism and Disposition October 2020, 48 (10) 944-955; DOI: https://doi.org/10.1124/dmd.120.090886

O

  1. Özvegy-Laczka, Csilla

    1. You have access
      Effects of Chrysin and Its Major Conjugated Metabolites Chrysin-7-Sulfate and Chrysin-7-Glucuronide on Cytochrome P450 Enzymes and on OATP, P-gp, BCRP, and MRP2 Transporters
      Violetta Mohos, Eszter Fliszár-Nyúl, Orsolya Ungvári, Éva Bakos, Katalin Kuffa, Tímea Bencsik, Balázs Zoltán Zsidó, Csaba Hetényi, Ágnes Telbisz, Csilla Özvegy-Laczka and Miklós Poór
      Drug Metabolism and Disposition October 2020, 48 (10) 1064-1073; DOI: https://doi.org/10.1124/dmd.120.000085

P

  1. Paine, Mary F.

    1. You have access
      Predicting the Potential for Cannabinoids to Precipitate Pharmacokinetic Drug Interactions via Reversible Inhibition or Inactivation of Major Cytochromes P450
      Sumit Bansal, Neha Maharao, Mary F. Paine and Jashvant D. Unadkat
      Drug Metabolism and Disposition October 2020, 48 (10) 1008-1017; DOI: https://doi.org/10.1124/dmd.120.000073
    2. Open Access
      A New Data Repository for Pharmacokinetic Natural Product-Drug Interactions: From Chemical Characterization to Clinical Studies
      Caroline Birer-Williams, Brandon T. Gufford, Eric Chou, Marijanel Alilio, Sidney VanAlstine, Rachael E. Morley, Jeannine S. McCune, Mary F. Paine and Richard D. Boyce
      Drug Metabolism and Disposition October 2020, 48 (10) 1104-1112; DOI: https://doi.org/10.1124/dmd.120.000054
    3. You have access
      Natural Products: Experimental Approaches to Elucidate Disposition Mechanisms and Predict Pharmacokinetic Drug Interactions
      Mary F. Paine
      Drug Metabolism and Disposition October 2020, 48 (10) 956-962; DOI: https://doi.org/10.1124/dmd.120.000182
    4. You have access
      Modulation of Major Human Liver Microsomal Cytochromes P450 by Component Alkaloids of Goldenseal: Time-Dependent Inhibition and Allosteric Effects
      Matthew G. McDonald, Dan-Dan Tian, Kenneth E. Thummel, Mary F. Paine and Allan E. Rettie
      Drug Metabolism and Disposition October 2020, 48 (10) 1018-1027; DOI: https://doi.org/10.1124/dmd.120.091041
  2. Pan, Sophie R.

    1. You have access
      Human Amyloid-β40 Kinetics after Intravenous and Intracerebroventricular Injections and Calcitriol Treatment in Rats In Vivo
      H. Benson Peng, Keumhan Noh, Sophie R. Pan, Victor Saldivia, Sylvia Serson, Anja Toscan, Inés A.M. de Lannoy and K. Sandy Pang
      Drug Metabolism and Disposition October 2020, 48 (10) 944-955; DOI: https://doi.org/10.1124/dmd.120.090886
  3. Pang, K. Sandy

    1. You have access
      Human Amyloid-β40 Kinetics after Intravenous and Intracerebroventricular Injections and Calcitriol Treatment in Rats In Vivo
      H. Benson Peng, Keumhan Noh, Sophie R. Pan, Victor Saldivia, Sylvia Serson, Anja Toscan, Inés A.M. de Lannoy and K. Sandy Pang
      Drug Metabolism and Disposition October 2020, 48 (10) 944-955; DOI: https://doi.org/10.1124/dmd.120.090886
  4. Parrott, Neil

    1. You have access
      Application of the Extended Clearance Classification System (ECCS) in Drug Discovery and Development: Selection of Appropriate In Vitro Tools and Clearance Prediction
      Kenichi Umehara, Carina Cantrill, Matthias Beat Wittwer, Elisa Di Lenarda, Florian Klammers, Aynur Ekiciler, Neil Parrott, Stephen Fowler and Mohammed Ullah
      Drug Metabolism and Disposition October 2020, 48 (10) 849-860; DOI: https://doi.org/10.1124/dmd.120.000133
  5. Pelletier, Robert D.

    1. You have access
      Mechanisms of Herb-Drug Interactions Involving Cinnamon and CYP2A6: Focus on Time-Dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde
      Michael J. Espiritu, Justin Chen, Jaydeep Yadav, Michael Larkin, Robert D. Pelletier, Jeannine M. Chan, Jeevan B. GC, Senthil Natesan and John P. Harrelson
      Drug Metabolism and Disposition October 2020, 48 (10) 1028-1043; DOI: https://doi.org/10.1124/dmd.120.000087
  6. Peng, H. Benson

    1. You have access
      Human Amyloid-β40 Kinetics after Intravenous and Intracerebroventricular Injections and Calcitriol Treatment in Rats In Vivo
      H. Benson Peng, Keumhan Noh, Sophie R. Pan, Victor Saldivia, Sylvia Serson, Anja Toscan, Inés A.M. de Lannoy and K. Sandy Pang
      Drug Metabolism and Disposition October 2020, 48 (10) 944-955; DOI: https://doi.org/10.1124/dmd.120.090886
  7. Pfaar, Ulrike

    1. Open Access
      Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite
      Ulrike Glaenzel, Yi Jin, Regine Hansen, Kirsten Schroer, Gholamreza Rahmanzadeh, Ulrike Pfaar, Jan Jaap van Lier, Hubert Borell, Axel Meissner, Gian Camenisch and Sylvia Zhao
      Drug Metabolism and Disposition October 2020, 48 (10) 873-885; DOI: https://doi.org/10.1124/dmd.119.090324
  8. Plesescu, Mihaela

    1. You have access
      Prediction of Human Disproportionate and Biliary Excreted Metabolites Using Chimeric Mice with Humanized Liver
      Suguru Kato, Abhi Shah, Mihaela Plesescu, Yoshinari Miyata, Jayaprakasam Bolleddula, Swapan Chowdhury and Xiaochun Zhu
      Drug Metabolism and Disposition October 2020, 48 (10) 934-943; DOI: https://doi.org/10.1124/dmd.120.000128
  9. Poór, Miklós

    1. You have access
      Effects of Chrysin and Its Major Conjugated Metabolites Chrysin-7-Sulfate and Chrysin-7-Glucuronide on Cytochrome P450 Enzymes and on OATP, P-gp, BCRP, and MRP2 Transporters
      Violetta Mohos, Eszter Fliszár-Nyúl, Orsolya Ungvári, Éva Bakos, Katalin Kuffa, Tímea Bencsik, Balázs Zoltán Zsidó, Csaba Hetényi, Ágnes Telbisz, Csilla Özvegy-Laczka and Miklós Poór
      Drug Metabolism and Disposition October 2020, 48 (10) 1064-1073; DOI: https://doi.org/10.1124/dmd.120.000085

Q

  1. Qian, Yuli

    1. You have access
      Natural Products as Modulators of CES1 Activity
      Yuli Qian and John S. Markowitz
      Drug Metabolism and Disposition October 2020, 48 (10) 993-1007; DOI: https://doi.org/10.1124/dmd.120.000065
  2. Qiu, Furong

    1. You have access
      Influence of Zuojin Pill on the Metabolism of Venlafaxine in Vitro and in Rats and Associated Herb-Drug Interaction
      Yue Li, Juan Li, Dongmin Yan, Qian Wang, Jingyi Jin, Bo Tan and Furong Qiu
      Drug Metabolism and Disposition October 2020, 48 (10) 1044-1052; DOI: https://doi.org/10.1124/dmd.120.000048
  3. Qiu, Xiazi

    1. You have access
      Quantification of Neonatal Fc Receptor and Beta-2 Microglobulin in Human Liver Tissues by Ultraperformance Liquid Chromatography–Multiple Reaction Monitoring–based Targeted Quantitative Proteomics for Applications in Biotherapeutic Physiologically-based Pharmacokinetic Models
      Xiazi Qiu and Michael Zhuo Wang
      Drug Metabolism and Disposition October 2020, 48 (10) 925-933; DOI: https://doi.org/10.1124/dmd.120.000075
  4. Quinn, Joseph F.

    1. You have access
      Centella asiatica Water Extract Shows Low Potential for Cytochrome P450–Mediated Drug Interactions
      Kirsten M. Wright, Armando Alcazar Magana, Ronald M. Laethem, Caroline L. Moseley, Troy T. Banks, Claudia S. Maier, Jan F. Stevens, Joseph F. Quinn and Amala Soumyanath
      Drug Metabolism and Disposition October 2020, 48 (10) 1053-1063; DOI: https://doi.org/10.1124/dmd.120.090860

R

  1. Rahmanzadeh, Gholamreza

    1. Open Access
      Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite
      Ulrike Glaenzel, Yi Jin, Regine Hansen, Kirsten Schroer, Gholamreza Rahmanzadeh, Ulrike Pfaar, Jan Jaap van Lier, Hubert Borell, Axel Meissner, Gian Camenisch and Sylvia Zhao
      Drug Metabolism and Disposition October 2020, 48 (10) 873-885; DOI: https://doi.org/10.1124/dmd.119.090324
  2. Rettie, Allan E.

    1. You have access
      Modulation of Major Human Liver Microsomal Cytochromes P450 by Component Alkaloids of Goldenseal: Time-Dependent Inhibition and Allosteric Effects
      Matthew G. McDonald, Dan-Dan Tian, Kenneth E. Thummel, Mary F. Paine and Allan E. Rettie
      Drug Metabolism and Disposition October 2020, 48 (10) 1018-1027; DOI: https://doi.org/10.1124/dmd.120.091041
  3. Riggs, Matthew M.

    1. Open Access
      Quantification of the Impact of Partition Coefficient Prediction Methods on Physiologically Based Pharmacokinetic Model Output Using a Standardized Tissue Composition
      Kiersten Utsey, Madeleine S. Gastonguay, Sean Russell, Reed Freling, Matthew M. Riggs and Ahmed Elmokadem
      Drug Metabolism and Disposition October 2020, 48 (10) 903-916; DOI: https://doi.org/10.1124/dmd.120.090498
  4. Roberts, John

    1. You have access
      Comparison of In Vitro to In Vivo Extrapolation Approaches for Predicting Transporter-Mediated Hepatic Uptake Clearance Using Suspended Rat Hepatocytes
      Na Li, Akshay Badrinarayanan, Xingwen Li, John Roberts, Mike Hayashi, Manpreet Virk and Anshul Gupta
      Drug Metabolism and Disposition October 2020, 48 (10) 861-872; DOI: https://doi.org/10.1124/dmd.120.000064
  5. Russell, Sean

    1. Open Access
      Quantification of the Impact of Partition Coefficient Prediction Methods on Physiologically Based Pharmacokinetic Model Output Using a Standardized Tissue Composition
      Kiersten Utsey, Madeleine S. Gastonguay, Sean Russell, Reed Freling, Matthew M. Riggs and Ahmed Elmokadem
      Drug Metabolism and Disposition October 2020, 48 (10) 903-916; DOI: https://doi.org/10.1124/dmd.120.090498

S

  1. Saldivia, Victor

    1. You have access
      Human Amyloid-β40 Kinetics after Intravenous and Intracerebroventricular Injections and Calcitriol Treatment in Rats In Vivo
      H. Benson Peng, Keumhan Noh, Sophie R. Pan, Victor Saldivia, Sylvia Serson, Anja Toscan, Inés A.M. de Lannoy and K. Sandy Pang
      Drug Metabolism and Disposition October 2020, 48 (10) 944-955; DOI: https://doi.org/10.1124/dmd.120.090886
  2. Schroer, Kirsten

    1. Open Access
      Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite
      Ulrike Glaenzel, Yi Jin, Regine Hansen, Kirsten Schroer, Gholamreza Rahmanzadeh, Ulrike Pfaar, Jan Jaap van Lier, Hubert Borell, Axel Meissner, Gian Camenisch and Sylvia Zhao
      Drug Metabolism and Disposition October 2020, 48 (10) 873-885; DOI: https://doi.org/10.1124/dmd.119.090324
  3. Serson, Sylvia

    1. You have access
      Human Amyloid-β40 Kinetics after Intravenous and Intracerebroventricular Injections and Calcitriol Treatment in Rats In Vivo
      H. Benson Peng, Keumhan Noh, Sophie R. Pan, Victor Saldivia, Sylvia Serson, Anja Toscan, Inés A.M. de Lannoy and K. Sandy Pang
      Drug Metabolism and Disposition October 2020, 48 (10) 944-955; DOI: https://doi.org/10.1124/dmd.120.090886
  4. Shah, Abhi

    1. You have access
      Prediction of Human Disproportionate and Biliary Excreted Metabolites Using Chimeric Mice with Humanized Liver
      Suguru Kato, Abhi Shah, Mihaela Plesescu, Yoshinari Miyata, Jayaprakasam Bolleddula, Swapan Chowdhury and Xiaochun Zhu
      Drug Metabolism and Disposition October 2020, 48 (10) 934-943; DOI: https://doi.org/10.1124/dmd.120.000128
  5. Shao, Yuhao

    1. Multiomics Profiling Reveals Protective Function of <em>Schisandra</em> Lignans against Acetaminophen-Induced Hepatotoxicity
      You have access
      Multiomics Profiling Reveals Protective Function of Schisandra Lignans against Acetaminophen-Induced Hepatotoxicity
      Caixia Yan, Huimin Guo, Qingqing Ding, Yuhao Shao, Dian Kang, Tengjie Yu, Changjian Li, Haoran Huang, Yisha Du, He Wang, Kangrui Hu, Lin Xie, Guangji Wang and Yan Liang
      Drug Metabolism and Disposition October 2020, 48 (10) 1092-1103; DOI: https://doi.org/10.1124/dmd.120.000083
  6. Shen, Hong

    1. You have access
      Detection of Weak Organic Anion–Transporting Polypeptide 1B Inhibition by Probenecid with Plasma-Based Coproporphyrin in Humans
      Yueping Zhang, Vinay K. Holenarsipur, Hamza Kandoussi, Jianing Zeng, T. Thanga Mariappan, Michael Sinz and Hong Shen
      Drug Metabolism and Disposition October 2020, 48 (10) 841-848; DOI: https://doi.org/10.1124/dmd.120.000076
  7. Shi, Yiwei

    1. The Effects of Traditional Chinese Medicine on P-Glycoprotein–Mediated Multidrug Resistance and Approaches for Studying the Herb–P-Glycoprotein Interactions
      You have access
      The Effects of Traditional Chinese Medicine on P-Glycoprotein–Mediated Multidrug Resistance and Approaches for Studying the Herb–P-Glycoprotein Interactions
      Yuhong Cao, Yiwei Shi, Ying Cai, Zhanying Hong and Yifeng Chai
      Drug Metabolism and Disposition October 2020, 48 (10) 972-979; DOI: https://doi.org/10.1124/dmd.120.000050
  8. Sinz, Michael

    1. You have access
      Detection of Weak Organic Anion–Transporting Polypeptide 1B Inhibition by Probenecid with Plasma-Based Coproporphyrin in Humans
      Yueping Zhang, Vinay K. Holenarsipur, Hamza Kandoussi, Jianing Zeng, T. Thanga Mariappan, Michael Sinz and Hong Shen
      Drug Metabolism and Disposition October 2020, 48 (10) 841-848; DOI: https://doi.org/10.1124/dmd.120.000076
  9. Soumyanath, Amala

    1. You have access
      Centella asiatica Water Extract Shows Low Potential for Cytochrome P450–Mediated Drug Interactions
      Kirsten M. Wright, Armando Alcazar Magana, Ronald M. Laethem, Caroline L. Moseley, Troy T. Banks, Claudia S. Maier, Jan F. Stevens, Joseph F. Quinn and Amala Soumyanath
      Drug Metabolism and Disposition October 2020, 48 (10) 1053-1063; DOI: https://doi.org/10.1124/dmd.120.090860
  10. Stevens, Jan F.

    1. You have access
      Centella asiatica Water Extract Shows Low Potential for Cytochrome P450–Mediated Drug Interactions
      Kirsten M. Wright, Armando Alcazar Magana, Ronald M. Laethem, Caroline L. Moseley, Troy T. Banks, Claudia S. Maier, Jan F. Stevens, Joseph F. Quinn and Amala Soumyanath
      Drug Metabolism and Disposition October 2020, 48 (10) 1053-1063; DOI: https://doi.org/10.1124/dmd.120.090860

T

  1. Tai, Ting

    1. Multidrug Resistance–Associated Protein 3 Is Responsible for the Efflux Transport of Curcumin Glucuronide from Hepatocytes to the Blood
      You have access
      Multidrug Resistance–Associated Protein 3 Is Responsible for the Efflux Transport of Curcumin Glucuronide from Hepatocytes to the Blood
      Yu-Meng Jia, Ting Zhu, Huan Zhou, Jin-Zi Ji, Ting Tai and Hong-Guang Xie
      Drug Metabolism and Disposition October 2020, 48 (10) 966-971; DOI: https://doi.org/10.1124/dmd.119.089193
  2. Tan, Bo

    1. You have access
      Influence of Zuojin Pill on the Metabolism of Venlafaxine in Vitro and in Rats and Associated Herb-Drug Interaction
      Yue Li, Juan Li, Dongmin Yan, Qian Wang, Jingyi Jin, Bo Tan and Furong Qiu
      Drug Metabolism and Disposition October 2020, 48 (10) 1044-1052; DOI: https://doi.org/10.1124/dmd.120.000048
  3. Telbisz, Ágnes

    1. You have access
      Effects of Chrysin and Its Major Conjugated Metabolites Chrysin-7-Sulfate and Chrysin-7-Glucuronide on Cytochrome P450 Enzymes and on OATP, P-gp, BCRP, and MRP2 Transporters
      Violetta Mohos, Eszter Fliszár-Nyúl, Orsolya Ungvári, Éva Bakos, Katalin Kuffa, Tímea Bencsik, Balázs Zoltán Zsidó, Csaba Hetényi, Ágnes Telbisz, Csilla Özvegy-Laczka and Miklós Poór
      Drug Metabolism and Disposition October 2020, 48 (10) 1064-1073; DOI: https://doi.org/10.1124/dmd.120.000085
  4. Thummel, Kenneth E.

    1. You have access
      Modulation of Major Human Liver Microsomal Cytochromes P450 by Component Alkaloids of Goldenseal: Time-Dependent Inhibition and Allosteric Effects
      Matthew G. McDonald, Dan-Dan Tian, Kenneth E. Thummel, Mary F. Paine and Allan E. Rettie
      Drug Metabolism and Disposition October 2020, 48 (10) 1018-1027; DOI: https://doi.org/10.1124/dmd.120.091041
  5. Tian, Dan-Dan

    1. You have access
      Modulation of Major Human Liver Microsomal Cytochromes P450 by Component Alkaloids of Goldenseal: Time-Dependent Inhibition and Allosteric Effects
      Matthew G. McDonald, Dan-Dan Tian, Kenneth E. Thummel, Mary F. Paine and Allan E. Rettie
      Drug Metabolism and Disposition October 2020, 48 (10) 1018-1027; DOI: https://doi.org/10.1124/dmd.120.091041
  6. Toscan, Anja

    1. You have access
      Human Amyloid-β40 Kinetics after Intravenous and Intracerebroventricular Injections and Calcitriol Treatment in Rats In Vivo
      H. Benson Peng, Keumhan Noh, Sophie R. Pan, Victor Saldivia, Sylvia Serson, Anja Toscan, Inés A.M. de Lannoy and K. Sandy Pang
      Drug Metabolism and Disposition October 2020, 48 (10) 944-955; DOI: https://doi.org/10.1124/dmd.120.090886
  7. Tsai, Tung-Hu

    1. Preclinical Transplacental Transfer and Pharmacokinetics of Fipronil in Rats
      You have access
      Preclinical Transplacental Transfer and Pharmacokinetics of Fipronil in Rats
      Ya-Ning Chang and Tung-Hu Tsai
      Drug Metabolism and Disposition October 2020, 48 (10) 886-893; DOI: https://doi.org/10.1124/dmd.120.000088

U

  1. Ullah, Mohammed

    1. You have access
      Application of the Extended Clearance Classification System (ECCS) in Drug Discovery and Development: Selection of Appropriate In Vitro Tools and Clearance Prediction
      Kenichi Umehara, Carina Cantrill, Matthias Beat Wittwer, Elisa Di Lenarda, Florian Klammers, Aynur Ekiciler, Neil Parrott, Stephen Fowler and Mohammed Ullah
      Drug Metabolism and Disposition October 2020, 48 (10) 849-860; DOI: https://doi.org/10.1124/dmd.120.000133
  2. Umehara, Ken-Ichi

    1. You have access
      A Study of the Effect of Cyclosporine on Fevipiprant Pharmacokinetics and its Absolute Bioavailability Using an Intravenous Microdose Approach
      H. Markus Weiss, Ken-Ichi Umehara, Veit J. Erpenbeck, Meredith Cain, Janardhana Vemula, Walid Elbast and Markus Zollinger
      Drug Metabolism and Disposition October 2020, 48 (10) 917-924; DOI: https://doi.org/10.1124/dmd.120.090852
  3. Umehara, Kenichi

    1. You have access
      Application of the Extended Clearance Classification System (ECCS) in Drug Discovery and Development: Selection of Appropriate In Vitro Tools and Clearance Prediction
      Kenichi Umehara, Carina Cantrill, Matthias Beat Wittwer, Elisa Di Lenarda, Florian Klammers, Aynur Ekiciler, Neil Parrott, Stephen Fowler and Mohammed Ullah
      Drug Metabolism and Disposition October 2020, 48 (10) 849-860; DOI: https://doi.org/10.1124/dmd.120.000133
  4. Unadkat, Jashvant D.

    1. You have access
      Predicting the Potential for Cannabinoids to Precipitate Pharmacokinetic Drug Interactions via Reversible Inhibition or Inactivation of Major Cytochromes P450
      Sumit Bansal, Neha Maharao, Mary F. Paine and Jashvant D. Unadkat
      Drug Metabolism and Disposition October 2020, 48 (10) 1008-1017; DOI: https://doi.org/10.1124/dmd.120.000073
  5. Ungvári, Orsolya

    1. You have access
      Effects of Chrysin and Its Major Conjugated Metabolites Chrysin-7-Sulfate and Chrysin-7-Glucuronide on Cytochrome P450 Enzymes and on OATP, P-gp, BCRP, and MRP2 Transporters
      Violetta Mohos, Eszter Fliszár-Nyúl, Orsolya Ungvári, Éva Bakos, Katalin Kuffa, Tímea Bencsik, Balázs Zoltán Zsidó, Csaba Hetényi, Ágnes Telbisz, Csilla Özvegy-Laczka and Miklós Poór
      Drug Metabolism and Disposition October 2020, 48 (10) 1064-1073; DOI: https://doi.org/10.1124/dmd.120.000085
  6. Utsey, Kiersten

    1. Open Access
      Quantification of the Impact of Partition Coefficient Prediction Methods on Physiologically Based Pharmacokinetic Model Output Using a Standardized Tissue Composition
      Kiersten Utsey, Madeleine S. Gastonguay, Sean Russell, Reed Freling, Matthew M. Riggs and Ahmed Elmokadem
      Drug Metabolism and Disposition October 2020, 48 (10) 903-916; DOI: https://doi.org/10.1124/dmd.120.090498

V

  1. VanAlstine, Sidney

    1. Open Access
      A New Data Repository for Pharmacokinetic Natural Product-Drug Interactions: From Chemical Characterization to Clinical Studies
      Caroline Birer-Williams, Brandon T. Gufford, Eric Chou, Marijanel Alilio, Sidney VanAlstine, Rachael E. Morley, Jeannine S. McCune, Mary F. Paine and Richard D. Boyce
      Drug Metabolism and Disposition October 2020, 48 (10) 1104-1112; DOI: https://doi.org/10.1124/dmd.120.000054
  2. Vemula, Janardhana

    1. You have access
      A Study of the Effect of Cyclosporine on Fevipiprant Pharmacokinetics and its Absolute Bioavailability Using an Intravenous Microdose Approach
      H. Markus Weiss, Ken-Ichi Umehara, Veit J. Erpenbeck, Meredith Cain, Janardhana Vemula, Walid Elbast and Markus Zollinger
      Drug Metabolism and Disposition October 2020, 48 (10) 917-924; DOI: https://doi.org/10.1124/dmd.120.090852
  3. Virk, Manpreet

    1. You have access
      Comparison of In Vitro to In Vivo Extrapolation Approaches for Predicting Transporter-Mediated Hepatic Uptake Clearance Using Suspended Rat Hepatocytes
      Na Li, Akshay Badrinarayanan, Xingwen Li, John Roberts, Mike Hayashi, Manpreet Virk and Anshul Gupta
      Drug Metabolism and Disposition October 2020, 48 (10) 861-872; DOI: https://doi.org/10.1124/dmd.120.000064

W

  1. Wang, Guangji

    1. Multiomics Profiling Reveals Protective Function of <em>Schisandra</em> Lignans against Acetaminophen-Induced Hepatotoxicity
      You have access
      Multiomics Profiling Reveals Protective Function of Schisandra Lignans against Acetaminophen-Induced Hepatotoxicity
      Caixia Yan, Huimin Guo, Qingqing Ding, Yuhao Shao, Dian Kang, Tengjie Yu, Changjian Li, Haoran Huang, Yisha Du, He Wang, Kangrui Hu, Lin Xie, Guangji Wang and Yan Liang
      Drug Metabolism and Disposition October 2020, 48 (10) 1092-1103; DOI: https://doi.org/10.1124/dmd.120.000083
  2. Wang, He

    1. Multiomics Profiling Reveals Protective Function of <em>Schisandra</em> Lignans against Acetaminophen-Induced Hepatotoxicity
      You have access
      Multiomics Profiling Reveals Protective Function of Schisandra Lignans against Acetaminophen-Induced Hepatotoxicity
      Caixia Yan, Huimin Guo, Qingqing Ding, Yuhao Shao, Dian Kang, Tengjie Yu, Changjian Li, Haoran Huang, Yisha Du, He Wang, Kangrui Hu, Lin Xie, Guangji Wang and Yan Liang
      Drug Metabolism and Disposition October 2020, 48 (10) 1092-1103; DOI: https://doi.org/10.1124/dmd.120.000083
  3. Wang, Michael Zhuo

    1. You have access
      Quantification of Neonatal Fc Receptor and Beta-2 Microglobulin in Human Liver Tissues by Ultraperformance Liquid Chromatography–Multiple Reaction Monitoring–based Targeted Quantitative Proteomics for Applications in Biotherapeutic Physiologically-based Pharmacokinetic Models
      Xiazi Qiu and Michael Zhuo Wang
      Drug Metabolism and Disposition October 2020, 48 (10) 925-933; DOI: https://doi.org/10.1124/dmd.120.000075
  4. Wang, Qian

    1. You have access
      Influence of Zuojin Pill on the Metabolism of Venlafaxine in Vitro and in Rats and Associated Herb-Drug Interaction
      Yue Li, Juan Li, Dongmin Yan, Qian Wang, Jingyi Jin, Bo Tan and Furong Qiu
      Drug Metabolism and Disposition October 2020, 48 (10) 1044-1052; DOI: https://doi.org/10.1124/dmd.120.000048
  5. Weber, Wendy J.

    1. You have access
      National Center for Complementary and Integrative Health Perspectives on Clinical Research Involving Natural Products
      Wendy J. Weber and D. Craig Hopp
      Drug Metabolism and Disposition October 2020, 48 (10) 963-965; DOI: https://doi.org/10.1124/dmd.120.000071
  6. Weiss, H. Markus

    1. You have access
      A Study of the Effect of Cyclosporine on Fevipiprant Pharmacokinetics and its Absolute Bioavailability Using an Intravenous Microdose Approach
      H. Markus Weiss, Ken-Ichi Umehara, Veit J. Erpenbeck, Meredith Cain, Janardhana Vemula, Walid Elbast and Markus Zollinger
      Drug Metabolism and Disposition October 2020, 48 (10) 917-924; DOI: https://doi.org/10.1124/dmd.120.090852
  7. Wittwer, Matthias Beat

    1. You have access
      Application of the Extended Clearance Classification System (ECCS) in Drug Discovery and Development: Selection of Appropriate In Vitro Tools and Clearance Prediction
      Kenichi Umehara, Carina Cantrill, Matthias Beat Wittwer, Elisa Di Lenarda, Florian Klammers, Aynur Ekiciler, Neil Parrott, Stephen Fowler and Mohammed Ullah
      Drug Metabolism and Disposition October 2020, 48 (10) 849-860; DOI: https://doi.org/10.1124/dmd.120.000133
  8. Wright, Kirsten M.

    1. You have access
      Centella asiatica Water Extract Shows Low Potential for Cytochrome P450–Mediated Drug Interactions
      Kirsten M. Wright, Armando Alcazar Magana, Ronald M. Laethem, Caroline L. Moseley, Troy T. Banks, Claudia S. Maier, Jan F. Stevens, Joseph F. Quinn and Amala Soumyanath
      Drug Metabolism and Disposition October 2020, 48 (10) 1053-1063; DOI: https://doi.org/10.1124/dmd.120.090860

X

  1. Xie, Hong-Guang

    1. Multidrug Resistance–Associated Protein 3 Is Responsible for the Efflux Transport of Curcumin Glucuronide from Hepatocytes to the Blood
      You have access
      Multidrug Resistance–Associated Protein 3 Is Responsible for the Efflux Transport of Curcumin Glucuronide from Hepatocytes to the Blood
      Yu-Meng Jia, Ting Zhu, Huan Zhou, Jin-Zi Ji, Ting Tai and Hong-Guang Xie
      Drug Metabolism and Disposition October 2020, 48 (10) 966-971; DOI: https://doi.org/10.1124/dmd.119.089193
  2. Xie, Lin

    1. Multiomics Profiling Reveals Protective Function of <em>Schisandra</em> Lignans against Acetaminophen-Induced Hepatotoxicity
      You have access
      Multiomics Profiling Reveals Protective Function of Schisandra Lignans against Acetaminophen-Induced Hepatotoxicity
      Caixia Yan, Huimin Guo, Qingqing Ding, Yuhao Shao, Dian Kang, Tengjie Yu, Changjian Li, Haoran Huang, Yisha Du, He Wang, Kangrui Hu, Lin Xie, Guangji Wang and Yan Liang
      Drug Metabolism and Disposition October 2020, 48 (10) 1092-1103; DOI: https://doi.org/10.1124/dmd.120.000083

Y

  1. Yadav, Jaydeep

    1. You have access
      Mechanisms of Herb-Drug Interactions Involving Cinnamon and CYP2A6: Focus on Time-Dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde
      Michael J. Espiritu, Justin Chen, Jaydeep Yadav, Michael Larkin, Robert D. Pelletier, Jeannine M. Chan, Jeevan B. GC, Senthil Natesan and John P. Harrelson
      Drug Metabolism and Disposition October 2020, 48 (10) 1028-1043; DOI: https://doi.org/10.1124/dmd.120.000087
  2. Yan, Caixia

    1. Multiomics Profiling Reveals Protective Function of <em>Schisandra</em> Lignans against Acetaminophen-Induced Hepatotoxicity
      You have access
      Multiomics Profiling Reveals Protective Function of Schisandra Lignans against Acetaminophen-Induced Hepatotoxicity
      Caixia Yan, Huimin Guo, Qingqing Ding, Yuhao Shao, Dian Kang, Tengjie Yu, Changjian Li, Haoran Huang, Yisha Du, He Wang, Kangrui Hu, Lin Xie, Guangji Wang and Yan Liang
      Drug Metabolism and Disposition October 2020, 48 (10) 1092-1103; DOI: https://doi.org/10.1124/dmd.120.000083
  3. Yan, Dongmin

    1. You have access
      Influence of Zuojin Pill on the Metabolism of Venlafaxine in Vitro and in Rats and Associated Herb-Drug Interaction
      Yue Li, Juan Li, Dongmin Yan, Qian Wang, Jingyi Jin, Bo Tan and Furong Qiu
      Drug Metabolism and Disposition October 2020, 48 (10) 1044-1052; DOI: https://doi.org/10.1124/dmd.120.000048
  4. Yi, Yaodong

    1. You have access
      Organic Cation Transporter 1 and 3 Contribute to the High Accumulation of Dehydrocorydaline in the Heart
      Yingchun Chen, Cui Li, Yaodong Yi, Weijuan Du, Huidi Jiang, Su Zeng and Hui Zhou
      Drug Metabolism and Disposition October 2020, 48 (10) 1074-1083; DOI: https://doi.org/10.1124/dmd.120.000025
  5. Yu, Tengjie

    1. Multiomics Profiling Reveals Protective Function of <em>Schisandra</em> Lignans against Acetaminophen-Induced Hepatotoxicity
      You have access
      Multiomics Profiling Reveals Protective Function of Schisandra Lignans against Acetaminophen-Induced Hepatotoxicity
      Caixia Yan, Huimin Guo, Qingqing Ding, Yuhao Shao, Dian Kang, Tengjie Yu, Changjian Li, Haoran Huang, Yisha Du, He Wang, Kangrui Hu, Lin Xie, Guangji Wang and Yan Liang
      Drug Metabolism and Disposition October 2020, 48 (10) 1092-1103; DOI: https://doi.org/10.1124/dmd.120.000083

Z

  1. Zeng, Jianing

    1. You have access
      Detection of Weak Organic Anion–Transporting Polypeptide 1B Inhibition by Probenecid with Plasma-Based Coproporphyrin in Humans
      Yueping Zhang, Vinay K. Holenarsipur, Hamza Kandoussi, Jianing Zeng, T. Thanga Mariappan, Michael Sinz and Hong Shen
      Drug Metabolism and Disposition October 2020, 48 (10) 841-848; DOI: https://doi.org/10.1124/dmd.120.000076
  2. Zeng, Su

    1. You have access
      Organic Cation Transporter 1 and 3 Contribute to the High Accumulation of Dehydrocorydaline in the Heart
      Yingchun Chen, Cui Li, Yaodong Yi, Weijuan Du, Huidi Jiang, Su Zeng and Hui Zhou
      Drug Metabolism and Disposition October 2020, 48 (10) 1074-1083; DOI: https://doi.org/10.1124/dmd.120.000025
  3. Zhang, Yueping

    1. You have access
      Detection of Weak Organic Anion–Transporting Polypeptide 1B Inhibition by Probenecid with Plasma-Based Coproporphyrin in Humans
      Yueping Zhang, Vinay K. Holenarsipur, Hamza Kandoussi, Jianing Zeng, T. Thanga Mariappan, Michael Sinz and Hong Shen
      Drug Metabolism and Disposition October 2020, 48 (10) 841-848; DOI: https://doi.org/10.1124/dmd.120.000076
  4. Zhao, Sylvia

    1. Open Access
      Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite
      Ulrike Glaenzel, Yi Jin, Regine Hansen, Kirsten Schroer, Gholamreza Rahmanzadeh, Ulrike Pfaar, Jan Jaap van Lier, Hubert Borell, Axel Meissner, Gian Camenisch and Sylvia Zhao
      Drug Metabolism and Disposition October 2020, 48 (10) 873-885; DOI: https://doi.org/10.1124/dmd.119.090324
  5. Zhou, Huan

    1. Multidrug Resistance–Associated Protein 3 Is Responsible for the Efflux Transport of Curcumin Glucuronide from Hepatocytes to the Blood
      You have access
      Multidrug Resistance–Associated Protein 3 Is Responsible for the Efflux Transport of Curcumin Glucuronide from Hepatocytes to the Blood
      Yu-Meng Jia, Ting Zhu, Huan Zhou, Jin-Zi Ji, Ting Tai and Hong-Guang Xie
      Drug Metabolism and Disposition October 2020, 48 (10) 966-971; DOI: https://doi.org/10.1124/dmd.119.089193
  6. Zhou, Hui

    1. You have access
      Organic Cation Transporter 1 and 3 Contribute to the High Accumulation of Dehydrocorydaline in the Heart
      Yingchun Chen, Cui Li, Yaodong Yi, Weijuan Du, Huidi Jiang, Su Zeng and Hui Zhou
      Drug Metabolism and Disposition October 2020, 48 (10) 1074-1083; DOI: https://doi.org/10.1124/dmd.120.000025
  7. Zhu, Ting

    1. Multidrug Resistance–Associated Protein 3 Is Responsible for the Efflux Transport of Curcumin Glucuronide from Hepatocytes to the Blood
      You have access
      Multidrug Resistance–Associated Protein 3 Is Responsible for the Efflux Transport of Curcumin Glucuronide from Hepatocytes to the Blood
      Yu-Meng Jia, Ting Zhu, Huan Zhou, Jin-Zi Ji, Ting Tai and Hong-Guang Xie
      Drug Metabolism and Disposition October 2020, 48 (10) 966-971; DOI: https://doi.org/10.1124/dmd.119.089193
  8. Zhu, Xiaochun

    1. You have access
      Prediction of Human Disproportionate and Biliary Excreted Metabolites Using Chimeric Mice with Humanized Liver
      Suguru Kato, Abhi Shah, Mihaela Plesescu, Yoshinari Miyata, Jayaprakasam Bolleddula, Swapan Chowdhury and Xiaochun Zhu
      Drug Metabolism and Disposition October 2020, 48 (10) 934-943; DOI: https://doi.org/10.1124/dmd.120.000128
  9. Zollinger, Markus

    1. You have access
      A Study of the Effect of Cyclosporine on Fevipiprant Pharmacokinetics and its Absolute Bioavailability Using an Intravenous Microdose Approach
      H. Markus Weiss, Ken-Ichi Umehara, Veit J. Erpenbeck, Meredith Cain, Janardhana Vemula, Walid Elbast and Markus Zollinger
      Drug Metabolism and Disposition October 2020, 48 (10) 917-924; DOI: https://doi.org/10.1124/dmd.120.090852
  10. Zsidó, Balázs Zoltán

    1. You have access
      Effects of Chrysin and Its Major Conjugated Metabolites Chrysin-7-Sulfate and Chrysin-7-Glucuronide on Cytochrome P450 Enzymes and on OATP, P-gp, BCRP, and MRP2 Transporters
      Violetta Mohos, Eszter Fliszár-Nyúl, Orsolya Ungvári, Éva Bakos, Katalin Kuffa, Tímea Bencsik, Balázs Zoltán Zsidó, Csaba Hetényi, Ágnes Telbisz, Csilla Özvegy-Laczka and Miklós Poór
      Drug Metabolism and Disposition October 2020, 48 (10) 1064-1073; DOI: https://doi.org/10.1124/dmd.120.000085
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Drug Metabolism and Disposition: 48 (10)
Drug Metabolism and Disposition
Vol. 48, Issue 10
1 Oct 2020
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